Low-density lipoprotein subtype separation kit

Abstract

The utility model relates to the technical field of biological detection, and discloses a low-density lipoprotein subtype separation kit which comprises a first bottom plate, a first spring is arranged on the upper surface of the first bottom plate, a rotating block is fixedly connected to the outer wall of the first spring, a first connecting column is fixedly connected to the upper surface of the rotating block, and a second connecting column is fixedly connected to the lower surface of the first connecting column. A button is fixedly connected to the upper surface of the first connecting column, a supporting plate is rotatably connected to the outer wall of the rotating block, the lower surface of the supporting plate is fixedly connected to the upper surface of the first bottom plate, clamping teeth are fixedly connected to the upper surface of the rotating block, and the outer walls of the clamping teeth are arranged on the inner wall of the clamping column; the outer walls of the clamping columns are slidably connected to the inner walls of the spring blocks. According to the reagent box, the first rotating arm drives the sliding block to move, the sliding block is used for compressing the second spring, and the second bottom plate drives the sliding column to slide on the inner wall of the supporting frame, so that the effect that the first box body and the second box body can also be used for distinguishing different reagents while the reagents in the paper sleeve are buffered and protected is achieved.

Description

Technical Field

[0001] The utility model relates to the technical field of biological detection, in particular to a low-density lipoprotein subtype separation kit. Background Art

[0002] The detection and analysis of blood lipid subfractions, particularly low-density lipoprotein (LDL) subtypes, is gaining increasing attention. As a key indicator of blood lipid levels, LDL plays a crucial role in the prevention, diagnosis, monitoring, and pathogenesis of cardiovascular disease. Low-density lipoprotein (LDL) is divided into seven subtypes, LDL-1 to LDL-7, based on density and particle diameter. Levels of sdLDL (LDL subtypes 3-7), a subfraction of LDL, are closely associated with cardiovascular disease risk and play a significant role in disease progression. Consequently, LDL subtype separation kits are gaining increasing clinical attention.

[0003] Conventional low-density lipoprotein subtype separation kits do not have the function of fixing the kit, which may cause damage due to bumps, collisions, etc. during storage and transportation. In addition, general low-density lipoprotein subtype separation kits do not have the function of separate storage, which can easily cause confusion among experimental operators and affect monitoring data. Utility Model Content

[0004] In order to make up for the above shortcomings, the utility model provides a low-density lipoprotein subtype separation kit, which aims to improve the problem that traditional low-density lipoprotein subtype separation kits do not have the function of fixing the kit, resulting in the kit being extremely susceptible to damage during storage and transportation.

[0005] To achieve the above objectives, the present invention provides the following technical solutions:

[0006] A low-density lipoprotein subtype separation kit comprises a first base plate, an upper surface of the first base plate is provided with a first spring, an outer wall of the first spring is fixedly connected to a rotating block, an upper surface of the rotating block is fixedly connected to a first connecting column, an upper surface of the first connecting column is fixedly connected to a button, an outer wall of the rotating block is rotatably connected to a support plate, a lower surface of the support plate is fixedly connected to the upper surface of the first base plate, an upper surface of the rotating block is fixedly connected to a latch, an outer wall of the latch is provided on the inner wall of the latch column, an outer wall of the latch column is slidably connected to the inner wall of the spring block, a lower surface of the spring block is fixedly connected to the upper surface of the first base plate, a support assembly is provided on the lower surface of the first base plate, and the support assembly is used to support a paper sleeve.

[0007] Preferably, the support assembly includes a second bottom plate, the upper surface of the second bottom plate is fixedly connected to the lower surface of the first bottom plate, and the inner wall of the second bottom plate is fixedly connected to a second connecting column.

[0008] Preferably, the outer wall of the second connecting column is rotatably connected to a first rotating arm, and the outer wall of the first rotating arm is rotatably connected to a second rotating arm.

[0009] Preferably, a slider is fixedly connected to the outer wall of the first rotating arm, and a second spring is provided on the outer wall of the slider.

[0010] Preferably, the outer wall of the second spring is fixedly connected to a support frame, and the inner wall of the support frame is slidably connected to the outer wall of the slider.

[0011] Preferably, a sliding column is fixedly connected to the lower surface of the second bottom plate, and an outer wall of the sliding column is slidably connected to the inner wall of the support frame.

[0012] Preferably, a third base plate is fixedly connected to the lower surface of the support frame, and an outer wall of the third base plate is rotatably connected to the outer wall of the second rotating arm.

[0013] Preferably, the outer wall of the clamping column is fixedly connected with a paper sleeve, the inner wall of the paper sleeve is provided with a first box body, the inner wall of the paper sleeve is provided with a second box body, the outer wall of the first box body is attached to the outer wall of the second box body, the inner wall of the first box body is provided with a gel column bottle, the inner wall of the gel column bottle is provided with a round pearl cotton pad, the inner wall of the gel column bottle is provided with a square pearl cotton pad, the outer wall of the round pearl cotton pad is attached to the outer wall of the square pearl cotton pad, the outer wall of the gel column bottle is provided with a plastic bottle cap, and the inner wall of the plastic bottle cap is fixedly connected with a round pearl cotton pad.

[0014] The utility model has the following beneficial effects:

[0015] 1. In the present invention, the plastic bottle cap is used to seal the gel column bottle, the first box body is used to place the gel column bottle that needs to be refrigerated, the second box body is used to place the electrophoresis buffer powder and lipoprotein staining solution stored at room temperature, the second bottom plate drives the second connecting column to move, the second connecting column drives the first rotating arm to rotate, the first rotating arm drives the second rotating arm to rotate, the first rotating arm drives the slider to move, the slider is used to compress the second spring, and the second bottom plate drives the sliding column to slide on the inner wall of the support frame, thereby achieving the effect of buffering and protecting the reagents inside the paper cover. At the same time, the first box body and the second box body can also be used to distinguish different reagents.

[0016] 2. In the present invention, the button drives the first connecting column to move, the first connecting column drives the rotating block to rotate, the rotating block is used to compress the first spring, the rotating block drives the latch to rotate, the latch is used to lock or release the latch, thereby achieving the effect of fixing the paper sleeve to prevent it from being damaged by collision during transportation. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1This is a stereoscopic diagram of a low-density lipoprotein subtype separation kit proposed in the present invention;

[0018] Figure 2 This is a schematic diagram of the local structure of the teeth of a low-density lipoprotein subtype separation kit proposed in the present invention;

[0019] Figure 3 This is a schematic diagram of the partial structure of a slider of a low-density lipoprotein subtype separation kit proposed in the present invention;

[0020] Figure 4 This is a schematic diagram of the partial structure of a paper box of a low-density lipoprotein subtype separation kit proposed in the present invention;

[0021] Figure 5 This is a schematic cross-sectional view of a gel column bottle of a low-density lipoprotein subtype separation kit proposed in the utility model.

[0022] Legend:

[0023] 1. First base plate; 2. First spring; 3. Rotating block; 4. First connecting column; 5. Button; 6. Support plate; 7. Clamping tooth; 8. Spring block; 9. Clamping column; 10. Second base plate; 11. Second connecting column; 12. First rotating arm; 13. Second rotating arm; 14. Slider; 15. Second spring; 16. Third base plate; 17. Sliding column; 18. Support frame; 19. Paper sleeve; 20. First box body; 21. Second box body; 22. Gel column bottle; 23. Round pearl cotton pad; 24. Square pearl cotton pad; 25. Plastic bottle cap. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings of the specification of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0025] Reference Figure 1-Figure 3, the utility model provides an embodiment: a low-density lipoprotein subtype separation kit, comprising a first base plate 1, an upper surface of the first base plate 1 is provided with a first spring 2, an outer wall of the first spring 2 is fixedly connected to a rotating block 3, an upper surface of the rotating block 3 is fixedly connected to a first connecting column 4, an upper surface of the first connecting column 4 is fixedly connected to a button 5, an outer wall of the rotating block 3 is rotatably connected to a support plate 6, a lower surface of the support plate 6 is fixedly connected to the upper surface of the first base plate 1, an upper surface of the rotating block 3 is fixedly connected to a latch 7, an outer wall of the latch 7 is provided on the inner wall of a latch column 9, an outer wall of the latch column 9 is slidably connected to the inner wall of a spring block 8, a lower surface of the spring block 8 is fixedly connected to the upper surface of the first base plate 1, a supporting assembly is provided on the lower surface of the first base plate 1, and the supporting assembly is used to support a paper sleeve 19;

[0026] Specifically, press the button 5, which is used to drive the first connecting column 4 to move. The movement of the first connecting column 4 is used to drive the rotating block 3 to rotate. The rotation of the rotating block 3 is used to compress the first spring 2. The rotation of the rotating block 3 is used to drive the latch 7 to rotate. The rotation of the latch 7 is used to lock or release the latch column 9, thereby achieving the effect of fixing the paper sleeve 19.

[0027] Reference Figure 1 and Figure 3 The support assembly includes a second base plate 10, the upper surface of the second base plate 10 is fixedly connected to the lower surface of the first base plate 1, and the inner wall of the second base plate 10 is fixedly connected to the second connecting column 11; the outer wall of the second connecting column 11 is rotatably connected to the first rotating arm 12, and the outer wall of the first rotating arm 12 is rotatably connected to the second rotating arm 13; the outer wall of the first rotating arm 12 is fixedly connected to the slider 14, and the outer wall of the slider 14 is provided with a second spring 15; the outer wall of the second spring 15 is fixedly connected to the support frame 18, and the inner wall of the support frame 18 is slidably connected to the outer wall of the slider 14; the lower surface of the second base plate 10 is fixedly connected to the sliding column 17, and the outer wall of the sliding column 17 is slidably connected to the inner wall of the support frame 18;

[0028] Specifically, the movement of the second base plate 10 is used to drive the movement of the second connecting column 11, the movement of the second connecting column 11 is used to drive the first rotating arm 12 to rotate, the rotation of the first rotating arm 12 is used to drive the second rotating arm 13 to rotate, the rotation of the first rotating arm 12 is used to drive the slider 14 to move, the movement of the slider 14 is used to compress the second spring 15, and the movement of the second base plate 10 is used to drive the sliding column 17 to slide on the inner wall of the support frame 18, thereby achieving the effect of buffering and protecting the reagents inside the paper sleeve 19.

[0029] Reference Figure 4 and Figure 5, the lower surface of the support frame 18 is fixedly connected to the third base plate 16, and the outer wall of the third base plate 16 is rotatably connected to the outer wall of the second rotating arm 13; the outer wall of the card column 9 is fixedly connected to the paper cover 19, the inner wall of the paper cover 19 is provided with a first box body 20, the inner wall of the paper cover 19 is provided with a second box body 21, the outer wall of the first box body 20 is attached to the outer wall of the second box body 21, the inner wall of the first box body 20 is provided with a gel column bottle 22, the inner wall of the gel column bottle 22 is provided with a round pearl cotton pad 23, the inner wall of the gel column bottle 22 is provided with a square pearl cotton pad 24, the outer wall of the round pearl cotton pad 23 is attached to the outer wall of the square pearl cotton pad 24, the outer wall of the gel column bottle 22 is provided with a plastic bottle cap 25, and the inner wall of the plastic bottle cap 25 is fixedly connected with the round pearl cotton pad 23;

[0030] Specifically, the plastic bottle cap 25 is used to seal the gel column bottle 22, the first box body 20 is used to place the gel column bottle 22 that needs to be refrigerated, and the second box body 21 is used to place the electrophoresis buffer powder and lipoprotein staining solution stored at room temperature.

[0031] Working principle: When the device needs to be used, first press the button 5, which will drive the first connecting column 4 on its lower surface to move. When the first connecting column 4 moves, it will drive the rotating block 3 on its lower surface to rotate. When the rotating block 3 rotates, it will drive the latching teeth 7 on its upper surface to rotate. When the rotating block 3 rotates, it will compress the first spring 2 on its lower surface. When the latching teeth 7 rotate, it will lock or unlock the latching column 9, thereby achieving the effect of fixing or unlocking the paper sleeve 19; when the second bottom plate 10 moves, it will drive the second connecting column 11 on its inner wall to move, and the movement of the second connecting column 11 will drive its The first rotating arm 12 of the outer wall rotates, and when the first rotating arm 12 rotates, it will drive the second rotating arm 13 of the outer wall to rotate. When the first rotating arm 12 rotates, it will drive the outer wall slider 14 to slide on the inner wall of the support frame 18. The second bottom plate 10 moves to drive the sliding column 17 to slide on the inner wall of the support frame 18, thereby achieving the effect of buffering and protecting the reagents inside the paper sleeve 19. Finally, the device can not only fix the paper sleeve 19 by rotating the latch 7, but also achieve the effect of buffering and protecting the reagents inside the first box body 20 and the second box body 21 by sliding the slider 14.

[0032] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A low-density lipoprotein subtype separation kit, comprising a first bottom plate (1), characterized in that: The upper surface of the first base plate (1) is provided with a first spring (2), the outer wall of the first spring (2) is fixedly connected to a rotating block (3), the upper surface of the rotating block (3) is fixedly connected to a first connecting column (4), the upper surface of the first connecting column (4) is fixedly connected to a button (5), the outer wall of the rotating block (3) is rotatably connected to a support plate (6), the lower surface of the support plate (6) is fixedly connected to the upper surface of the first base plate (1), the upper surface of the rotating block (3) is fixedly connected to a latch (7), the outer wall of the latch (7) is provided on the inner wall of the latch column (9), the outer wall of the latch column (9) is slidably connected to the inner wall of the spring block (8), the lower surface of the spring block (8) is fixedly connected to the upper surface of the first base plate (1), and the lower surface of the first base plate (1) is provided with a support assembly, and the support assembly is used to support the paper sleeve (19).

2. A low-density lipoprotein subtype separation kit according to claim 1, characterized in that: The support assembly comprises a second base plate (10), the upper surface of the second base plate (10) is fixedly connected to the lower surface of the first base plate (1), and the inner wall of the second base plate (10) is fixedly connected to a second connecting column (11).

3. A low-density lipoprotein subtype separation kit according to claim 2, characterized in that: The outer wall of the second connecting column (11) is rotatably connected to a first rotating arm (12), and the outer wall of the first rotating arm (12) is rotatably connected to a second rotating arm (13).

4. A low-density lipoprotein subtype separation kit according to claim 3, characterized in that: The outer wall of the first rotating arm (12) is fixedly connected to a slider (14), and the outer wall of the slider (14) is provided with a second spring (15).

5. A low-density lipoprotein subtype separation kit according to claim 4, characterized in that: The outer wall of the second spring (15) is fixedly connected to a support frame (18), and the inner wall of the support frame (18) is slidably connected to the outer wall of the slider (14).

6. A low-density lipoprotein subtype separation kit according to claim 2, characterized in that: A sliding column (17) is fixedly connected to the lower surface of the second bottom plate (10), and the outer wall of the sliding column (17) is slidably connected to the inner wall of the support frame (18).

7. A low-density lipoprotein subtype separation kit according to claim 6, characterized in that: The lower surface of the support frame (18) is fixedly connected to a third base plate (16), and the outer wall of the third base plate (16) is rotatably connected to the outer wall of the second rotating arm (13).

8. The low-density lipoprotein subtype separation kit according to claim 1, characterized in that: The outer wall of the clamping column (9) is fixedly connected with a paper sleeve (19), the inner wall of the paper sleeve (19) is provided with a first box body (20), the inner wall of the paper sleeve (19) is provided with a second box body (21), the outer wall of the first box body (20) is attached to the outer wall of the second box body (21), the inner wall of the first box body (20) is provided with a gel column bottle (22), the inner wall of the gel column bottle (22) is provided with a circular pearl cotton pad (23), the inner wall of the gel column bottle (22) is provided with a square pearl cotton pad (24), the outer wall of the circular pearl cotton pad (23) is attached to the outer wall of the square pearl cotton pad (24), the outer wall of the gel column bottle (22) is provided with a plastic bottle cap (25), and the inner wall of the plastic bottle cap (25) is fixedly connected with the circular pearl cotton pad (23).

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