Sterile cryopreservation bottle cell resuscitation water bath floating plate

Through the innovative design of silicone substrate and anti-overflow plate structure, the problem of floating plate material being unable to be effectively fixed is solved, and the stable fixation of sterile frozen bottles and sealing and anti-pollution are achieved, which improves the efficiency and safety of cell resuscitation.

CN223268664UActive Publication Date: 2025-08-26SHANGHAI HUIMMUTECH BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422958820.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-03
Publication Date
2025-08-26
Estimated Expiration
2034-12-03

AI Technical Summary

Technical Problem

The existing floating plate materials cannot effectively fix sterile frozen storage bottles of varying weights, which have low conductivity efficiency and are prone to sealing contamination and affect cell resuscitation effect.

Method used

The silicone substrate and upper anti-overflow plate structure are adopted, combined with the corrugated pipe and limit rod design, to achieve stable fixation and adaptive adjustment of the sterile frozen bottle to prevent sealing contamination.

Benefits of technology

The stable fixation of sterile frozen storage bottles is achieved, avoiding sealing contamination, improving conduction efficiency, and ensuring the effectiveness and safety of cell resuscitation.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a cell resuscitation water bath floating plate for a sterile cryopreservation bottle. A cell resuscitation water bath floating plate for a sterile cryopreservation bottle comprises a floating plate, the floating plate is a silica gel substrate made of silica gel materials, and cryopreservation bottle fixing holes for the sterile cryopreservation bottle to penetrate through are formed in the silica gel substrate; the device further comprises an upper-layer anti-overflow plate, through holes in one-to-one correspondence with the cryopreservation bottle fixing holes are formed in the upper-layer anti-overflow plate, the inner diameter of the through holes is larger than that of the cryopreservation bottle fixing holes, and the lower ends of the through holes are fixedly connected with the peripheral areas of the cryopreservation bottle fixing holes through corrugated pipes. By additionally arranging the upper-layer anti-overflow plate, the stretching degree of the corrugated pipe can be conveniently controlled through the distance between the upper-layer anti-overflow plate and the floating plate, and then water bath liquid is prevented from entering the sealing opening of the sterile cryopreservation bottle. After the upper-layer anti-overflow plate is fixed, the self-adaptive adjustment of the distance between the floating plate and the upper-layer anti-overflow plate can be conveniently realized by the floating plate according to the liquid level height of the water bath through the arrangement of the corrugated pipe.
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Description

Technical Field

[0001] The utility model relates to the technical field of machinery, in particular to a water bath floating plate. Background Art

[0002] During the clinical use of cell products, it is necessary to resuscitate the sterile cryopreservation bottles of frozen cells within a specified time. Most resuscitation operations are performed using a water bath. It is common to use a floating plate to fix the sterile cryopreservation bottle and then float it on the water bath liquid surface.

[0003] Existing float plates are made of foam or hard plastic materials. There are some defects in the float plates of this structure. First, the hard plastic float plate has a smooth inner diameter. When the sterile cryopreservation bottle is light in weight, it cannot be effectively fixed, and the sterile cryopreservation bottle is easy to float during use; second, the thickness of the foam float plate is usually more than 5 mm, and the float plate wraps a large part of the sterile cryopreservation bottle wall, so the sterile cryopreservation bottle cannot fully contact the water bath environment, the conduction efficiency is reduced, and there is a possibility of cell recovery timeout, which affects the activity of the cells after recovery; third, the float plate is a flat plate structure. During operation, the liquid can easily overflow the float plate, causing the sterile cryopreservation bottle seal to enter the water bath liquid, which can easily contaminate the product and affect its use. Utility Model Content

[0004] The utility model aims at solving the problems and shortcomings of the prior art and provides a water bath float for reviving cells in sterile cryopreservation bottles.

[0005] The utility model solves the above technical problems through the following technical solutions:

[0006] The utility model provides a sterile cryopreservation bottle cell recovery water bath float, comprising a float plate, characterized in that the float plate is a silicone base plate made of silicone material, and a cryopreservation bottle fixing hole for passing the sterile cryopreservation bottle is opened on the silicone base plate;

[0007] It also includes an upper anti-overflow plate, on which a through hole is provided that corresponds one-to-one with the cryopreservation bottle fixing hole. The inner diameter of the through hole is larger than the inner diameter of the cryopreservation bottle fixing hole, and the lower end of the through hole is fixedly connected to the outer area of ​​the cryopreservation bottle fixing hole through a bellows.

[0008] The utility model adds an upper anti-overflow plate, which facilitates controlling the stretching degree of the bellows through the distance between the upper anti-overflow plate and the floating plate, thereby preventing the water bath liquid from entering the sealing part of the sterile cryopreservation bottle.

[0009] After the upper anti-overflow plate is fixed, the bellows are provided to facilitate the adaptive adjustment of the distance between the floating plate and the upper overflow plate according to the liquid level of the water bath.

[0010] The inner diameter of the through hole is larger than the inner diameter of the fixing hole of the freezing bottle, which facilitates the operation of taking out the sterile freezing bottle after the bellows is compressed.

[0011] Further preferably, the outer edge of the upper anti-overflow plate is connected to a hook for hanging on the side wall of the water bath.

[0012] Further preferably, the upper anti-overflow plate is a plastic plate.

[0013] Further preferably, a limit rod is threadedly connected to the upper anti-overflow plate.

[0014] It is convenient to limit the minimum value of the relative position distance between the upper anti-overflow plate and the silicone base plate by adjusting the upper and lower positions of the limit rod.

[0015] Further preferably, the outer edge of the upper anti-overflow plate is provided with an annular protrusion extending upward.

[0016] Further preferably, a protrusion for detachably connecting to a counterweight ring is provided on the outer edge of the silicone substrate, and a snap-in hole for snapping the protrusion is provided on the counterweight ring.

[0017] By adding a counterweight ring, the deadweight is increased, and the silicone substrate is pulled downward, making it easier to immerse the sterile cryopreservation bottle in the water bath and speeding up the water bath processing time.

[0018] Further preferably, the thickness of the silicone substrate is 1-3 mm.

[0019] On the basis of conforming to the common sense in this field, the above-mentioned preferred conditions can be arbitrarily combined to obtain the preferred embodiments of the present utility model.

[0020] The positive progressive effect of the utility model is that the utility model fixes the sterile cryopreservation bottle through the silica gel substrate and avoids the sealing portion of the sterile cryopreservation bottle from being immersed in the water bath liquid. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a structural diagram of a specific embodiment 1 of the present utility model;

[0022] Figure 2 This is a structural diagram of a specific embodiment 2 of the present utility model;

[0023] Figure 3 This is a structural diagram of a specific embodiment 3 of the present utility model;

[0024] Figure 4 This is a structural diagram of specific embodiment 4 of the present utility model. DETAILED DESCRIPTION

[0025] To make the purpose, technical solutions, and advantages of the embodiments of the present invention more clear, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts shall fall within the scope of protection of the present invention.

[0026] like Figure 1 As shown in specific embodiment 1, a sterile cryopreservation bottle cell recovery water bath float comprises a float plate, which is a silicone substrate 1 made of silicone material, and the silicone substrate 1 is provided with a cryopreservation bottle fixing hole 11 for passing the sterile cryopreservation bottle; and further comprises an upper anti-overflow plate 2, which is provided with a through hole 21 arranged one-to-one with the cryopreservation bottle fixing hole 11, the inner diameter of the through hole 21 being larger than the inner diameter of the cryopreservation bottle fixing hole 11, and the lower end of the through hole 21 is fixedly connected to the peripheral area of ​​the cryopreservation bottle fixing hole 11 through a bellows 3. By adding the upper anti-overflow plate 2, the utility model facilitates the control of the stretching degree of the bellows 3 by the spacing between the upper anti-overflow plate 2 and the float plate, thereby preventing the sterile cryopreservation bottle seal from entering the water bath liquid. When the upper anti-overflow plate 2 is fixed, the bellows 3 are provided to facilitate the adaptive adjustment of the spacing between the float plate and the upper overflow plate according to the liquid level of the water bath. The inner diameter of the through hole 21 is larger than the inner diameter of the freezing bottle fixing hole 11 , so that the operation of taking out the sterile freezing bottle is facilitated after the bellows 3 is compressed.

[0027] The outer edge of the upper anti-overflow plate 2 is connected to a hook 4 for hanging on the side wall of the water bath.

[0028] The thickness of the silicone substrate 1 is 1-3 mm.

[0029] The inner diameter of the freezing bottle fixing hole 11 is interference-fitted with the tube wall of the sterile freezing bottle. The aperture of the freezing bottle fixing hole can be 12-15 mm.

[0030] The floating plate can be made of a polyurethane elastomer with a hardness of A50, which can meet the requirements of a water bath environment during cell recovery operations. The material has moderate tensile elasticity and can secure the sterile cryopreservation bottles.

[0031] See also Figure 2 In a second embodiment, based on the first embodiment, the upper anti-overflow plate 2 is a plastic plate. A limit rod 5 is threadedly connected to the upper anti-overflow plate 2. By adjusting the limit rod 5 up and down, the minimum relative distance between the upper anti-overflow plate 2 and the silicone substrate 1 can be controlled.

[0032] See also Figure 3Specific embodiment 3, based on specific embodiment 1, the outer edge of the upper anti-overflow plate 2 is provided with an annular protrusion 22 extending upward.

[0033] See also Figure 4 Specific Example 4, based on Specific Example 1, features a protrusion on the outer edge of the silicone base plate 1 for removable connection to a weight ring 6. The weight ring 6 has a snap-on hole for the protrusion. The addition of the weight ring 6 increases the weight, pulling the silicone base plate 1 downward, facilitating immersion of sterile cryopreservation bottles in the water bath and accelerating water bath processing time. The bottom of the hook is threadedly connected to the upper overflow plate, facilitating disassembly.

[0034] Specific embodiment 5, based on specific embodiment 1, a horizontally arranged nylon bolt is threadedly connected to the hook, and the nylon bolt abuts against the side wall of the water bath to facilitate fixing.

[0035] Although specific embodiments of the present invention have been described above, those skilled in the art will appreciate that these are merely illustrative and that the scope of protection of the present invention is defined by the appended claims. Those skilled in the art may make various changes or modifications to these embodiments without departing from the principles and essence of the present invention, and such changes and modifications are intended to fall within the scope of protection of the present invention.

Claims

1. A sterile frozen bottle cell recovery water bath float, comprising a floating plate, characterized in that: The floating plate is a silicone substrate made of silicone material, and a cryostat fixing hole for passing a sterile cryostat is opened on the silicone substrate; It also includes an upper anti-overflow plate, on which a through hole is provided that corresponds one-to-one with the cryopreservation bottle fixing hole. The inner diameter of the through hole is larger than the inner diameter of the cryopreservation bottle fixing hole, and the lower end of the through hole is fixedly connected to the outer area of ​​the cryopreservation bottle fixing hole through a bellows.

2. A sterile cryopreservation bottle cell recovery water bath float as claimed in claim 1, characterized in that: The outer edge of the upper anti-overflow plate is connected to a hook for hanging on the side wall of the water bath.

3. The sterile cryopreservation bottle cell recovery water bath float according to claim 1, characterized in that: The upper anti-overflow plate is a plastic plate.

4. A sterile cryopreservation bottle cell recovery water bath float as claimed in claim 1, characterized in that: The upper anti-overflow plate is threadedly connected to a limit rod.

5. The sterile cryopreservation bottle cell recovery water bath float as claimed in claim 1, characterized in that: The outer edge of the upper anti-overflow plate is provided with an annular protrusion extending upward.

6. A sterile cryopreservation bottle cell recovery water bath float as claimed in claim 1, characterized in that: The outer edge of the silicone base plate is provided with a protrusion for detachably connecting to the counterweight ring, and the counterweight ring is provided with a clamping hole for clamping the protrusion.

7. The sterile cryopreservation bottle cell recovery water bath float according to claim 1, characterized in that: The thickness of the silica gel substrate is 1-3 mm.