Freeze-drying device for improving freeze-drying effect of dry powder quality control product

Abstract

The utility model relates to the technical field of freeze-drying of freeze-dried powder, and discloses a freeze-drying device for improving the freeze-drying effect of a dry powder quality control product, which comprises a freeze-drying box, the left side and the right side of the freeze-drying box are communicated and are fixedly provided with airflow boxes, the two far sides of the two airflow boxes are communicated and are fixedly provided with circulating pipelines, and the circulating pipelines are connected with an external refrigerating system. And drying assemblies are arranged on the rear side and the interior of the freeze-drying box correspondingly, and each drying assembly comprises a warm air input box fixed to the rear side of the freeze-drying box. According to the medicine liquid freeze-drying device, the three storage trays are arranged for uniformly placing medicine liquid, so that the stacking height of the frozen medicine liquid is low, sublimation of water vapor of the frozen medicine liquid on the lower layer is reduced, the purity of medicine powder is improved, and the freeze-drying effect is improved; the three storage plates are arranged, so that the three storage plates can make uniform contact with warm air, liquid medicine in the storage plates is heated, the three storage plates are heated synchronously, and the drying speed of the liquid medicine is increased.

Description

Technical Field

[0001] The utility model relates to the technical field of freeze-drying of freeze-dried powder, in particular to a freeze-drying device for improving the freeze-drying effect of dry powder quality control products. Background Art

[0002] Lyophilized powder is made by pre-freezing the water in the drug solution using the vacuum freeze-drying method of a freeze dryer, and then sublimating the frozen water in the drug solution in a vacuum and sterile environment to achieve freeze-drying.

[0003] An existing freeze-dried powder production device (Announcement No.: CN117433254B) has at least the following disadvantages: when drying the liquid medicine on the placement box, the device can only dry the liquid medicine on a single placement box at a time, and cannot dry the liquid medicine on multiple groups of placement boxes at the same time, resulting in a slow drying speed of the liquid medicine. For this reason, the present utility model is proposed. Utility Model Content

[0004] The purpose of the utility model is to solve the shortcomings of the prior art and to propose a freeze-drying device that improves the freeze-drying effect of dry powder quality control products.

[0005] In order to achieve the above purpose, the present invention adopts the following technical solutions:

[0006] A freeze-drying device for improving the freeze-drying effect of dry powder quality control products includes a freeze-drying box, the left and right sides of the freeze-drying box are connected to and fixed with airflow boxes, the two sides away from the two airflow boxes are connected to and fixed with circulation pipes, the circulation pipes are connected to an external refrigeration system, the rear side and interior of the freeze-drying box are both provided with drying components, the drying component includes a heating input box fixed to the rear side of the freeze-drying box, the rear side of the heating input box is connected to and fixed with a heating input pipe, and three storage trays are provided inside the freeze-drying box.

[0007] As a further solution of the present invention, the internal front side of the heating input box is connected to and fixed with three solenoid valves, and the three solenoid valves are respectively located above the three storage trays. A first connecting pipe is provided on the top surface of the freeze drying box, and the two ends of the first connecting pipe are connected to and fixed with the two air flow boxes. The outer wall of the first connecting pipe is connected to and fixed with a second connecting pipe. A water vapor filter is provided on the right side of the freeze drying box, and a vacuum air pump is provided on the right side of the water vapor filter. One end of the second connecting pipe is connected to the input port of the water vapor filter, and the exhaust pipe of the vacuum air pump is connected to the output port of the water vapor filter.

[0008] As a further solution of the present invention, three fixing frames are fixed inside the freeze drying box, two clamping bars are arranged inside the fixing frames, the storage tray is clamped between the two clamping bars, and a telescopic rod and a telescopic cylinder are fixed on both sides of the clamping bars close to the fixing frames. The telescopic rod and the telescopic cylinder are slidably inserted inside, and a spring is fixed between one end of the telescopic rod and one side of the inner wall of the telescopic cylinder.

[0009] As a further solution of the present invention, air pressure sensors are fixed to the right side of the heating input box and the top surface of the freeze-drying box.

[0010] As a further solution of the present invention, three guide plates are fixed inside the freeze-drying box. The cross section of the guide plates is a triangular structure, and the three guide plates are respectively located below the three fixing frames.

[0011] As a further solution of the present invention, the front side of the freeze drying box is connected to a sealed door via a hinge, the sealed door hasp is locked with the freeze drying box, and a sealing strip is provided on the sealed door.

[0012] Compared with the prior art, the present invention has the following beneficial effects:

[0013] By arranging three storage trays to evenly place the liquid medicine, the accumulation height of the liquid medicine after being frozen is low, reducing the sublimation of water vapor in the lower layer of frozen liquid medicine, which is beneficial to improving the purity of the powder medicine, thereby increasing the freeze-drying effect. After the liquid medicine is frozen, heat is continuously input to the three storage trays through the heating input box, so that the three storage trays can be evenly exposed to the heat, and the liquid medicine in the storage trays is heated. The three storage trays are heated synchronously, which increases the drying speed of the liquid medicine. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic diagram of the three-dimensional structure of a freeze-drying device proposed in the present invention for improving the freeze-drying effect of dry powder quality control products;

[0015] Figure 2 This is a schematic diagram of the three-dimensional disassembled structure of a freeze-drying device proposed in the present invention for improving the freeze-drying effect of dry powder quality control products;

[0016] Figure 3 This is a schematic diagram of the three-dimensional structure of the fixed frame of a freeze-drying device for improving the freeze-drying effect of dry powder quality control products proposed in the present invention;

[0017] Figure 4 This is a schematic diagram of the three-dimensional split structure of the heating input box of a freeze-drying device proposed by the present invention to improve the freeze-drying effect of dry powder quality control products.

[0018] In the figure: 1. Freeze drying box; 101. Air flow box; 102. Circulation pipe; 2. Heating input box; 201. Heating input pipe; 202. Storage tray; 203. First connecting pipe; 204. Second connecting pipe; 205. Water vapor filter; 206. Vacuum air pump; 207. Solenoid valve; 3. Fixed frame; 301. Clamping strip; 302. Telescopic rod; 303. Telescopic cylinder; 304. Spring; 4. Air pressure sensor; 5. Guide plate; 6. Sealing door. DETAILED DESCRIPTION

[0019] In order to make the technical means, creative features, objectives and effects achieved by the present invention easier to understand, the present invention is further described below in conjunction with specific implementation methods.

[0020] In the description of this utility model, it should be noted that the terms "upper," "lower," "inner," "outer," "front end," "rear end," "both ends," "one end," "the other end," and the like, indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings and are intended solely to facilitate the description of this utility model and simplify the description. They are not intended to indicate or imply that the devices or components referred to must have a specific orientation, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limitations on this utility model. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0021] In the description of this utility model, it should be noted that, unless otherwise expressly specified or limited, the terms "installed," "provided with," "connected," etc. should be understood in a broad sense. For example, "connected" can mean a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be internal communication between two components. Those skilled in the art will be able to understand the specific meanings of the above terms in this utility model based on the specific circumstances.

[0022] like Figure 1-Figure 4 As shown, a freeze-drying device for improving the freeze-drying effect of dry powder quality control products includes a freeze-drying box 1, the left and right sides of the freeze-drying box 1 are connected and fixed with airflow boxes 101, the two sides away from the two airflow boxes 101 are connected and fixed with circulation pipes 102, the circulation pipes 102 are connected to the external refrigeration system, the rear side and interior of the freeze-drying box 1 are provided with drying components, the drying components include a heating input box 2 fixed on the rear side of the freeze-drying box 1, the rear side of the heating input box 2 is connected and fixed with a heating input pipe 201, and three storage trays 202 are provided inside the freeze-drying box 1.

[0023] like Figure 2-Figure 4As shown, in this embodiment, the inner front side of the heating input box 2 is connected and fixed with three electromagnetic valves 207, and the three electromagnetic valves 207 are respectively located above the three storage trays 202. The top surface of the freeze drying box 1 is provided with a first connecting pipe 203, and the two ends of the first connecting pipe 203 are connected and fixed to the two air flow boxes 101. The outer wall of the first connecting pipe 203 is connected and fixed with a second connecting pipe 204. A water vapor filter 205 is provided on the right side of the freeze drying box 1, and a vacuum air pump 206 is provided on the right side of the water vapor filter 205. One end of the second connecting pipe 204 is connected to the input port of the water vapor filter 205, and the exhaust pipe of the vacuum air pump 206 is connected to the output port of the water vapor filter 205. By placing the medicinal liquid on the three storage trays 202 respectively, and then The storage tray 202 is placed inside the freeze drying chamber 1, and cold air is input into the freeze drying chamber 1 through the circulation pipe 102 to freeze the liquid medicine. Then, the vacuum air pump 206 is used to continuously extract the air inside the freeze drying chamber 1 so that the interior of the freeze drying chamber 1 is maintained in a negative pressure state. At this time, warm air is continuously input into the heating input box 2. Then, the three solenoid valves 207 are opened to continuously input warm air to the three storage trays 202 respectively, so that the three storage trays 202 can be evenly exposed to the warm air, and the liquid medicine in the storage trays 202 is heated. The three storage trays 202 are heated synchronously to increase the drying speed of the liquid medicine. Then, the ice in the liquid medicine sublimates into water vapor, and the water vapor is extracted by the vacuum air pump 206 and enters the water vapor filter 205 to be filtered and processed.

[0024] like Figure 2-Figure 4 As shown, in this embodiment, three fixing frames 3 are fixed inside the freeze drying box 1, and two clamping bars 301 are arranged inside the fixing frames 3. The storage tray 202 is clamped between the two clamping bars 301, and telescopic rods 302 and telescopic cylinders 303 are fixed on both sides of the clamping bars 301 close to the fixing frames 3. The telescopic rods 302 and the telescopic cylinders 303 are slidably inserted inside, and a spring 304 is fixed between one end of the telescopic rod 302 and one side of the inner wall of the telescopic cylinder 303. By placing the storage tray 202 between the two storage trays 202, and then through the elastic force of the spring 304, the clamping bars 301 clamp and fix the storage tray 202.

[0025] like Figure 2-Figure 4 As shown, in this embodiment, air pressure sensors 4 are fixed to the right side of the heating input box 2 and the top surface of the freeze drying box 1. The air pressure sensor 4 can detect the air pressure inside the heating input box 2 and the freeze drying box 1 in real time, thereby ensuring that there is sufficient air pressure inside the heating input box 2, ensuring that the heating is stably input into the freeze drying box 1, ensuring that the inside of the freeze drying box 1 maintains a low pressure state, and ensuring that the ice in the medicine solution can sublime into water vapor.

[0026] like Figure 2-Figure 4As shown, in this embodiment, three guide plates 5 are fixed inside the freeze drying box 1. The cross-section of the guide plates 5 is a triangular structure. The three guide plates 5 are respectively located under the three fixing frames 3. By setting the guide plates 5, the warm air input into the storage tray 202 can be guided, so that the warm air can better flow along the bottom slope of the guide plates 5 to the air flow box 101 and be discharged from the interior of the freeze drying box 1.

[0027] like Figure 2-Figure 4 As shown, in this embodiment, the front side of the freeze drying box 1 is connected to a sealed door 6 by a hinge, and the sealed door 6 is locked with the freeze drying box 1 by a buckle. A sealing strip is provided on the sealed door 6. By opening the sealed door 6, the liquid medicine to be freeze-dried is injected into the storage tray 202, and then the sealed door 6 is closed and locked with the freeze drying box 1 by a buckle. The airtightness inside the freeze drying box 1 is ensured by the sealing strip provided on the sealed door 6.

[0028] From the above description, it can be seen that the above-mentioned embodiment of the present invention achieves the following technical effects: in use, by injecting the liquid medicine to be freeze-dried into the storage tray 202, then opening the sealing door 6, placing the storage tray 202 between the two storage trays 202, and then through the elastic force of the spring 304, the clamping strip 301 clamps and fixes the storage tray 202, and then closes the sealing door 6 and locks it with the freeze drying box 1 with a buckle, and the air tightness inside the freeze drying box 1 is ensured by the sealing strip provided on the sealing door 6, and cold air is input into the freeze drying box 1 through the circulation pipe 102 to freeze the liquid medicine, and then the vacuum air pump 206 is used to continuously extract the air inside the freeze drying box 1, and the pressure sensor 4 is used to determine the air pressure inside the freeze drying box. 1 maintains a negative pressure state, and at this time, warm air is continuously input into the heating input box 2. When the air pressure sensor 4 detects that the air pressure inside the heating input box 2 is maintained at a predetermined value, the three solenoid valves 207 are opened to continuously input warm air to the three storage trays 202 respectively, so that the three storage trays 202 can be evenly exposed to the warm air, and the medicine liquid in the storage trays 202 is heated. The three storage trays 202 are heated synchronously to increase the drying speed of the medicine liquid. Subsequently, the ice in the medicine liquid sublimates into water vapor, and the warm air flows along the bottom inclined surface of the guide plate 5 to the air flow box 101 and is discharged from the interior of the freeze drying box 1. The water vapor is extracted by the vacuum air pump 206 and enters the water vapor filter 205 to be filtered and processed, thereby completing the preparation of the freeze-dried powder.

[0029] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are merely illustrative of the principles of the present invention. Various changes and improvements may be made to the present invention without departing from the spirit and scope of the present invention, and such changes and improvements shall fall within the scope of the present invention as claimed.

Claims

1. A freeze-drying device for improving the freeze-drying effect of dry powder quality control products, comprising a freeze-drying chamber (1), characterized in that: The left and right sides of the freeze drying box (1) are both connected and fixed with air flow boxes (101), and the two sides away from the two air flow boxes (101) are both connected and fixed with circulation pipes (102), and the circulation pipes (102) are connected to the external refrigeration system. The rear side and the interior of the freeze drying box (1) are both provided with drying components, and the drying components include a heating input box (2) fixed on the rear side of the freeze drying box (1), and the rear side of the heating input box (2) is connected and fixed with a heating input pipe (201), and three storage trays (202) are provided inside the freeze drying box (1).

2. A freeze-drying device for improving the freeze-drying effect of dry powder quality control products according to claim 1, characterized in that: The front inner side of the heating input box (2) is connected to and fixed with three electromagnetic valves (207), which are respectively located above the three storage trays (202). A first connecting pipe (203) is provided on the top surface of the freeze drying box (1), and both ends of the first connecting pipe (203) are connected to and fixed with the two air flow boxes (101). A second connecting pipe (204) is connected to and fixed on the outer wall of the first connecting pipe (203). A water vapor filter (205) is provided on the right side of the freeze drying box (1), and a vacuum air pump (206) is provided on the right side of the water vapor filter (205). One end of the second connecting pipe (204) is connected to the input port of the water vapor filter (205), and the exhaust pipe of the vacuum air pump (206) is connected to the output port of the water vapor filter (205).

3. A freeze-drying device for improving the freeze-drying effect of dry powder quality control products according to claim 2, characterized in that: Three fixing frames (3) are fixed inside the freeze drying box (1), two clamping bars (301) are arranged inside the fixing frames (3), and the storage tray (202) is clamped between the two clamping bars (301). A telescopic rod (302) and a telescopic cylinder (303) are fixed on both sides of the clamping bars (301) close to the fixing frames (3), respectively. The telescopic rod (302) and the telescopic cylinder (303) are slidably inserted inside, and a spring (304) is fixed between one end of the telescopic rod (302) and one side of the inner wall of the telescopic cylinder (303).

4. A freeze-drying device for improving the freeze-drying effect of dry powder quality control products according to claim 3, characterized in that: Air pressure sensors (4) are fixed on the right side of the heating input box (2) and the top surface of the freeze drying box (1).

5. A freeze-drying device for improving the freeze-drying effect of dry powder quality control products according to claim 4, characterized in that: Three guide plates (5) are fixed inside the freeze drying box (1), and the cross section of the guide plates (5) is a triangular structure. The three guide plates (5) are respectively located below the three fixing frames (3).

6. A freeze-drying device for improving the freeze-drying effect of dry powder quality control products according to claim 5, characterized in that: The front side of the freeze drying box (1) is connected to a sealing door (6) via a hinge. The sealing door (6) is locked to the freeze drying box (1) by a buckle, and a sealing strip is provided on the sealing door (6).

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