Sample adding gun for phosphorylated antibody

By designing the limiting mechanism and scale marks with the sample loading gun, the problem of low sample loading accuracy of the sample loading gun is solved, and a more stable sample loading process is achieved.

CN223288098UActive Publication Date: 2025-09-02NANJING CHUANGENG INVESTMENT CO LTD
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Patent Information

Application Number
CN202422480805.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-14
Publication Date
2025-09-02
Estimated Expiration
2034-10-14

AI Technical Summary

Technical Problem

During the phosphorylated antibody experiment, the sample addition accuracy of the sample loading gun is easily affected by mistake, resulting in poor use.

Method used

A sample loading gun for phosphorylated antibodies including a sample loading cylinder, a fixing plate, a sealing plug, a push rod, a limiting mechanism, etc. is designed. Through the coordination of the limiting mechanism and the scale mark, the stability and accuracy of the sample loading process are ensured.

Benefits of technology

The sample addition accuracy of the sample loading gun is improved to prevent the impact of accidentally touching, and the sample loading process is more stable and reliable.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of sample adding guns, and discloses a sample adding gun for a phosphorylated antibody. Comprising a sample adding cylinder, a fixing plate and a sample adding needle, the fixing plate is fixedly connected to the top end of the sample adding cylinder, a sealing plug is slidably arranged on the inner wall of the sample adding cylinder, a push rod is fixedly connected to the top end of the sealing plug, an anti-skid base plate is fixedly connected to the side wall of the sample adding cylinder, and a fixing ring is fixedly connected to the top end of the fixing plate. The top end rod wall of the push rod penetrates through the fixing plate and the fixing ring and is fixedly connected with a gland. The push gland enables the push rod to move downwards, the sealing plug can move downwards to conduct sample adding treatment on a sample, the strip-shaped transparent plate and the scale marks can be observed more stably, the spring can push the sliding plate and the limiting block to extend into the push rod when the sample is not added, the limiting block is arranged on the side wall of the tooth in a pressing mode, and the sample adding effect is better. The push rod can be stably arranged in the sample adding cylinder, so that the influence of mistaken touch on the sample adding precision is prevented.
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Description

Technical Field

[0001] The utility model relates to the technical field of sample adding guns, in particular to a sample adding gun for phosphorylated antibodies. Background Art

[0002] Phosphoantibodies are a class of antibodies that target specific phosphorylation sites. They can recognize and bind to phosphorylated proteins. These antibodies have important applications in biomedical research, especially in the study of signal transduction, cell cycle regulation, and other biological processes. A pipette is a laboratory instrument primarily used to accurately aspirate and dispense liquid samples. It is widely used in biochemistry, molecular biology, medicine, and chemistry.

[0003] In the prior art, during the phosphorylated antibody experiment, a sample pipetting gun is required to pipette samples. However, high precision is required during pipetting. Accidental contact of the push rod can affect the pipetting accuracy and the effectiveness of the pipetting gun. Therefore, the present invention designs a sample pipetting gun for phosphorylated antibodies. Utility Model Content

[0004] The purpose of the utility model is to solve the problem in the prior art that, during the experiment process of phosphorylated antibodies, a sample adding gun needs to be used to add samples, and high precision is required during the addition of samples. If the push rod is accidentally touched, the addition precision of the sample adding gun will be affected, affecting the use effect of the sample adding gun. A sample adding gun for phosphorylated antibodies is proposed.

[0005] In order to achieve the above purpose, the present invention adopts the following technical solutions:

[0006] A sample loading gun for phosphorylated antibodies comprises a sample loading barrel, a fixing plate and a sample loading needle, wherein the fixing plate is fixedly connected to the top end of the sample loading barrel, a sealing plug is slidably provided on the inner wall of the sample loading barrel, a push rod is fixedly connected to the top end of the sealing plug, a non-slip pad is fixedly connected to the side wall of the sample loading barrel, a fixing ring is fixedly connected to the top end of the fixing plate, the top end rod wall of the push rod passes through the fixing plate and the fixing ring and is fixedly connected to a pressure cover, and a limiting mechanism is provided inside the fixing ring.

[0007] Preferably, a strip opening is opened on the wall of the sample adding cylinder, a strip transparent plate is fixedly connected to the inner wall of the sample adding cylinder located at the strip opening, and scale lines are provided on the inner wall of the sample adding cylinder located at the strip opening.

[0008] Preferably, a non-slip rubber pad is fixedly connected to the interior of the fixing plate, and a plurality of protrusions are provided on the bottom of the non-slip rubber pad.

[0009] Preferably, the limiting mechanism includes a slide plate, a limiting block, a spring and a plurality of teeth. A cavity is provided inside the fixing ring, a strip-shaped opening is provided on the inner wall of the push rod, and the plurality of teeth are respectively fixedly connected to the push rod on the inner wall of the strip opening. The slide plate is slidingly arranged inside the cavity, the limiting block is fixedly connected to the side wall of the slide plate, a plurality of tooth grooves are provided on the side wall of the limiting block and are pressed against the side wall of the teeth, the spring is fixedly connected to the fixing ring inside the cavity, and the side wall of the slide plate is pressed against the end of the spring.

[0010] Preferably, a stabilizing block is fixedly connected to the side wall of the slide, a rectangular groove is opened on the inner wall of the cavity of the fixing ring, the stabilizing block is slidably arranged on the inner wall of the rectangular groove, and an anti-slip pad is fixedly connected to the side wall of the limit block.

[0011] Preferably, a pull rod is rotatably connected to the side wall of the slide, the rod wall of the pull rod extends to the outside of the fixed ring and is fixedly connected to the pull ring, a stop block is provided on the rod wall of the pull rod, an opening is provided on the side wall of the fixed ring, and the stop block is slidably set on the inner wall of the opening.

[0012] Compared with the prior art, the present invention provides a phosphorylated antibody sample gun, which has the following beneficial effects:

[0013] 1. The phosphorylated antibody sample gun can push the cover to move the push rod downward, and the sealing plug can be moved downward to add the sample. The strip transparent plate and scale lines can be observed more stably. When no sample is added, the spring can push the slide and the limit block to extend into the inside of the push rod, so that the limit block is pressed tightly against the side wall of the teeth, so that the push rod can be stably set in the inside of the sample tube to prevent accidental touch from affecting the accuracy of the sample addition.

[0014] 2. The phosphorylated antibody sample gun can improve the stability of the slider movement by sliding the stabilizing block along the inner wall of the rectangular groove. Pulling the pull ring can pull the pull rod to move, so that the limit block is retracted to the inside of the cavity, which is convenient for subsequent pushing and pulling of the push rod. After the block moves out along the opening to the outside of the fixed ring, the pull ring is rotated to press the block against the side wall of the fixed ring, so that the limit block can be stably set inside the cavity without affecting the push rod. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 This is a schematic structural diagram of a phosphorylated antibody pipetting gun proposed in the present invention;

[0016] Figure 2 for Figure 1 A schematic diagram of the structure of the partial A in the middle part;

[0017] Figure 3 for Figure 1 Top view of the structure of the middle putter.

[0018] In the figure: 1 sample tube, 2 fixed plate, 3 sample needle, 4 sealing plug, 5 push rod, 6 pressure cover, 7 anti-slip pad, 8 strip transparent plate, 9 scale line, 10 fixed ring, 11 anti-slip rubber pad, 12 slide plate, 13 limit block, 14 spring, 15 teeth, 16 anti-slip pad, 17 stabilizing block, 18 pull rod, 19 pull ring, 20 stop block. DETAILED DESCRIPTION

[0019] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0020] Example 1

[0021] Reference Figure 1-3 A sample loading gun for phosphorylated antibodies includes a sample loading barrel 1, a fixed plate 2 and a sample loading needle 3. The fixed plate 2 is fixedly connected to the top of the sample loading barrel 1. A sealing plug 4 is slidingly provided on the inner wall of the sample loading barrel 1. The top of the sealing plug 4 is fixedly connected to a push rod 5. An anti-slip pad 7 is fixedly connected to the side wall of the sample loading barrel 1. A fixing ring 10 is fixedly connected to the top of the fixed plate 2. The top rod wall of the push rod 5 passes through the fixing plate 2 and the fixing ring 10 and is fixedly connected to a pressure cover 6.

[0022] A strip opening is opened on the wall of the sample adding cylinder 1, and a strip transparent plate 8 is fixedly connected to the inner wall of the sample adding cylinder 1 located at the strip opening. A scale line 9 is provided on the inner wall of the sample adding cylinder 1 located at the strip opening. A non-slip rubber pad 11 is fixedly connected to the inside of the fixed plate 2, and a plurality of protrusions are provided on the bottom of the non-slip rubber pad 11.

[0023] A limiting mechanism is provided inside the fixed ring 10, which includes a slide plate 12, a limiting block 13, a spring 14 and a plurality of teeth 15. A cavity is provided inside the fixed ring 10, and a strip-shaped opening is provided on the inner wall of the push rod 5. The plurality of teeth 15 are respectively fixedly connected to the inner wall of the push rod 5 located at the strip-shaped opening. The slide plate 12 is slidably arranged inside the cavity, and the limiting block 13 is fixedly connected to the side wall of the slide plate 12. The side wall of the limiting block 13 is provided with a plurality of tooth grooves and is pressed against the side wall of the teeth 15. The spring 14 is fixedly connected to the fixed ring 10 inside the cavity, and the side wall of the slide plate 12 is pressed against the end of the spring 14.

[0024] When in use, the anti-slip pad 7 and the fixed plate 2 can make the sample adding cylinder 1 more stable to take, and the sample adding gun 1 is more stable when in use, and the sample adding needle 3 is convenient for subsequent sample adding processing. Pushing the pressure cover 10 can make the push rod 5 move down, and the sealing plug 4 can be moved down to add the sample. The strip transparent plate 8 and the scale line 9 can be observed more stably. When no sample is added, the spring 14 can push the slide plate 12 and the limit block 13 to extend to the inside of the push rod 5, so that the limit block 13 is pressed tightly against the side wall of the tooth 15, so that the push rod 15 can be stably set inside the sample adding cylinder 1 to prevent accidental touch from affecting the accuracy of sample addition.

[0025] Example 2

[0026] Reference Figure 1-3 A stabilizing block 17 is fixedly connected to the side wall of the skateboard 12, a rectangular groove is opened on the inner wall of the cavity of the fixing ring 10, and the stabilizing block 17 is slidably set on the inner wall of the rectangular groove. An anti-slip pad 16 is fixedly connected to the side wall of the limit block 13, and a pull rod 18 is rotatably connected to the side wall of the skateboard 12. The rod wall of the pull rod 18 extends to the outside of the fixing ring 10 and is fixedly connected to a pull ring 19. A stopper 20 is provided on the rod wall of the pull rod 18, and an opening is opened on the side wall of the fixing ring 10. The stopper 20 is slidably set on the inner wall of the opening.

[0027] The stabilizing block 17 slides along the inner wall of the rectangular groove to improve the stability of the movement of the slider 12. Pulling the pull ring 19 can pull the pull rod 18 to move, so that the limit block 13 shrinks to the inside of the cavity, which is convenient for the subsequent pushing and pulling of the push rod 5. After the stop block 20 moves out along the opening to the outside of the fixing ring 10, the pull ring 19 is rotated to press the stop block 20 against the side wall of the fixing ring 10, so that the limit block 13 can be stably set inside the cavity without affecting the push rod 5.

[0028] The above is only a preferred specific implementation method of the present invention, but the protection scope of the present invention is not limited to this. Any technician familiar with the technical field within the technical scope disclosed by the present invention can make equivalent replacements or changes based on the technical solution and utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A sample loading gun for phosphorylated antibodies, comprising a sample loading barrel (1), a fixing plate (2) and a sample loading needle (3), characterized in that: The fixing plate (2) is fixedly connected to the top of the sample adding cylinder (1); a sealing plug (4) is slidably provided on the inner wall of the sample adding cylinder (1); a push rod (5) is fixedly connected to the top of the sealing plug (4); an anti-slip pad (7) is fixedly connected to the side wall of the sample adding cylinder (1); a fixing ring (10) is fixedly connected to the top of the fixing plate (2); the top rod wall of the push rod (5) passes through the fixing plate (2) and the fixing ring (10) and is fixedly connected to a pressure cover (6); a limiting mechanism is provided inside the fixing ring (10).

2. The phosphorylated antibody pipetting gun according to claim 1, characterized in that: The sample adding cylinder (1) has a strip opening on its wall, a strip transparent plate (8) is fixedly connected to the inner wall of the sample adding cylinder (1) located at the strip opening, and a scale line (9) is provided on the inner wall of the sample adding cylinder (1) located at the strip opening.

3. The phosphorylated antibody pipetting gun according to claim 1, characterized in that: An anti-skid rubber pad (11) is fixedly connected to the interior of the fixing plate (2), and a plurality of protrusions are provided on the bottom of the anti-skid rubber pad (11).

4. The phosphorylated antibody pipetting gun according to claim 1, characterized in that: The limiting mechanism includes a slide plate (12), a limiting block (13), a spring (14) and a plurality of teeth (15); a cavity is provided inside the fixing ring (10); a strip-shaped opening is provided on the inner wall of the push rod (5); the plurality of teeth (15) are respectively fixedly connected to the inner wall of the push rod (5) located at the strip-shaped opening; the slide plate (12) is slidably arranged inside the cavity; the limiting block (13) is fixedly connected to the side wall of the slide plate (12); a plurality of tooth grooves are provided on the side wall of the limiting block (13) and pressed against the side wall of the teeth (15); the spring (14) is fixedly connected to the fixing ring (10) inside the cavity; the side wall of the slide plate (12) is pressed against the end of the spring (14).

5. The phosphorylated antibody pipetting gun according to claim 4, characterized in that: A stabilizing block (17) is fixedly connected to the side wall of the slide plate (12); a rectangular groove is provided on the inner wall of the cavity of the fixing ring (10); the stabilizing block (17) is slidably arranged on the inner wall of the rectangular groove; and an anti-slip pad (16) is fixedly connected to the side wall of the limit block (13).

6. The phosphorylated antibody pipetting gun according to claim 4, characterized in that: A pull rod (18) is rotatably connected to the side wall of the slide plate (12), the rod wall of the pull rod (18) extends to the outside of the fixed ring (10) and is fixedly connected to a pull ring (19), a stopper (20) is provided on the rod wall of the pull rod (18), an opening is provided on the side wall of the fixed ring (10), and the stopper (20) is slidably arranged on the inner wall of the opening.