Bottle cap assembly

Abstract

The utility model discloses a bottle cap assembly which is used for sealing a double-cavity clamping type bottle and comprises a top plug and a top cap. The top plug is pressed by the plug pressing assembly so as to be embedded with the double-cavity clamping type bottle, so that the double-cavity clamping type bottle is sealed; the top cover is used for fixing the top plug and sealing a bottle opening of the double-cavity clamping bottle; the plug pressing assembly comprises a press-in jig and a holding jig. According to the bottle cap assembly and the double-cavity clamping type bottle, high-precision self-plug-pressing sealing with good sealing performance can be conducted through the plug pressing assembly in a freeze dryer, meanwhile, the time cost and operation complexity needed by plug pressing and cover sealing of the double-cavity clamping type bottle in the whole freeze-drying technological process are reduced, and the freeze-drying efficiency and the freeze-drying product quality are improved.

Description

Technical Field

[0001] The present application relates to the fields of biopharmaceuticals, cosmetics, or medical aesthetics, and more specifically, to a bottle cap assembly. Background Art

[0002] Currently, the vast majority of lyophilized products on the market are packaged in vials. Prior to injection, the reconstitution solvent must be withdrawn from a separate container containing the reconstitution solvent using a sterile syringe. This reconstitution solvent is then injected into the drug container for reconstitution, withdrawal, and administration. This results in relatively poor dosing accuracy and user compliance. Dual-chamber cartridges offer a superior packaging option. Dual-chamber cartridges are divided into two chambers by a central stopper: the front chamber for the lyophilized drug and the rear chamber for the reconstitution solvent. During use, the reconstitution solvent is bypassed by pushing the bottom stopper into the front chamber to reconstitute the lyophilized drug. Once fully dissolved, the bottom stopper is pushed back to the top to complete the injection. Dual-chamber cartridges are an innovative pharmaceutical packaging solution used globally in biopharmaceuticals, cosmetics, and medical aesthetics. Compatible with a variety of delivery devices, they offer advantages such as ease of use, high patient safety, and high compliance, and hold a broad range of potential applications.

[0003] However, conventional dual-chamber cartridge packaging materials cannot achieve self-sealing and sealing within the freeze-drying machine. Therefore, it is necessary to design an innovative packaging material that can achieve self-sealing and sealing within the freeze-drying chamber to meet the airtightness requirements of the freeze-drying process and enable the packaging material to meet future drug delivery methods. For example, the closure device and sealing component for the container disclosed in CN102259723A have high sealing properties, but cannot meet the requirements of sublimation of product moisture (mainly gas) from the container during the freeze-drying process. Therefore, this type of packaging material cannot be directly used in the freeze-drying process. It may require an additional sealing step, which increases time and cost, and may affect the freeze-drying effect of the drug in the container during container transfer.

[0004] Therefore, there is an urgent need for a bottle cap assembly that can solve the above problems and is compatible with the double-chamber cartridge bottle packaging material, which can stably complete self-pressing and sealing in the freeze dryer cavity to improve the freeze-drying efficiency and quality of the freeze-dried product, fill the current gap in the domestic double-chamber cartridge bottle packaging material field, and enhance the core competitiveness of the product. Utility Model Content

[0005] The present application aims to provide a solution that can overcome at least one of the above-mentioned defects of the prior art.

[0006] The present application provides a bottle cap assembly, which may include a top plug and a top cover for sealing a dual-chamber cartridge. The top plug seals the mouth of the dual-chamber cartridge; the top plug is pressed into engagement with the dual-chamber cartridge by a pressing plug assembly to seal the dual-chamber cartridge; the top cover is used to secure the top plug and hermetically seal the mouth of the dual-chamber cartridge; the pressing plug assembly may include a pressing jig and a retaining jig.

[0007] In one embodiment of the present application, a dual-chamber cartridge may include an inner cavity, a body, a neck, and a mouth. A mouth opening connected to the inner cavity may be provided at the center of the mouth, and the inner diameter of the mouth opening may be smaller than the inner diameters of the mouth and neck. A bypass may be provided on one outer wall of the body. When the dual-chamber cartridge is placed on a lyophilization rack, the upper opening of the rack is larger than the lower opening. Therefore, the upper opening facilitates insertion of the bypass, while the lower opening securely secures the dual-chamber cartridge, preventing it from falling out of the mounting module and thereby preventing the cartridge from tilting or falling during the lyophilization process.

[0008] In one embodiment of the present application, the top plug may include a plug cap and a plug rod. The diameter of the plug rod is slightly larger than the inner diameter of the bottle mouth opening. After the plug rod is inserted into the bottle mouth opening, the lower surface of the plug cap completely fits the upper surface of the bottle mouth. Because the diameter of the plug rod is slightly larger than the inner diameter of the bottle mouth opening, when the top plug is pressed by the pressing plug assembly, the pressure provided by the pressing plug assembly must be greater than the pressure between the outer wall of the plug rod and the inner wall of the bottle mouth opening. After the top plug is engaged with the bottle mouth of the dual-chamber cartridge, the friction between the plug rod and the bottle mouth opening prevents the top plug from slipping out of the bottle mouth due to external forces such as gravity and centrifugal force, thereby ensuring the safe sealing of the lyophilized drug in the dual-chamber cartridge.

[0009] In one embodiment of the present application, the pressing jig may be a cylinder with an opening at the bottom and a depression in the center of the upper surface; when the top plug moves toward the bottle mouth, the lower surface of the pressing jig presses the top plug toward the bottle mouth, causing the top plug to be embedded in the bottle mouth.

[0010] In one embodiment of the present application, the retaining jig is configured such that its inner wall fits against the bottle mouth and bottle body, with its upper end protruding from the bottle mouth; and as the top plug moves toward the bottle mouth, the inner wall of the pressing jig fits against and slides against at least a portion of the outer wall of the retaining jig. The fitting and sliding contact between the pressing jig and the retaining jig during the plugging process allows the pressing jig to press the top plug in a direction perpendicular to the outer wall of the retaining jig, ensuring the movement stability of the pressing jig itself and ensuring that the pressure column consistently applies vertical pressure to the plug cap, further improving the accuracy of plugging.

[0011] In one embodiment of the present application, the retaining jig may also be provided with a raised portion. The raised portion supports and secures the top plug before it is inserted into the bottle mouth, aligning the plug rod with the bottle mouth opening; and the raised portion secures the top plug after it is inserted into the bottle mouth. The raised portion secures the top plug after it is inserted into the bottle mouth, thereby preventing the top plug from being inserted into the bottle mouth in an abnormal state, such as the outer edge of the top plug cap partially tilting up and partially sinking into the bottle mouth opening, or the plug rod of the top plug not being fully inserted into the bottle mouth opening. Therefore, the retaining jig also facilitates fine-tuning the insertion of the top plug, further improving the accuracy of the plugging process.

[0012] In one embodiment of the present application, the number of raised portions is two, three, or more. The raised portions extend radially along the retaining jig and are evenly spaced circumferentially on the inner wall of the retaining jig. When the top plug is forced to move toward the bottle mouth, the entire plug cap can move horizontally and evenly toward the bottle mouth, and is less likely to tilt. In this way, the occurrence of plugging failure can be significantly reduced.

[0013] In one embodiment of the present application, the top cover may include a main body and a bottom plate. The main body may include a top plate and an annular thread. The inner wall of the top cover is in contact with the bottle mouth and neck; and the bottom plate of the top cover is completely in contact with the upper surface of the bottle body. The main body of the top cover may be fixedly secured to a top plug embedded in the bottle mouth by the top plate. After the bottom plate is in contact with the upper surface of the bottle body, the top cover seals the bottle mouth, neck, and the connection between the neck and the bottle body, thereby providing a complete seal for the bottle mouth with the top plug embedded therein, and enhancing the sealing effect of the bottle mouth. The annular thread is configured to threadably engage with a sterile injection needle.

[0014] The present application also provides a dual-chamber cartridge bottle packaging material for injection, which includes a bottle cap assembly and a dual-chamber cartridge bottle provided in the present application.

[0015] Compared with the prior art, this application has at least one of the following technical effects:

[0016] 1. The present application provides a bottle cap assembly and a dual-chamber cartridge bottle, as well as a plugging assembly, which can assist the bottle cap assembly in plugging and capping the dual-chamber cartridge bottle.

[0017] 2. The bottle cap assembly of the present application can improve the fit tightness between the top plug, the top cap and the double-chamber cartridge.

[0018] 3. The bottle cap assembly of the present application can be used for high-precision self-pressing and capping of double-chamber cartridge bottles in the overall freeze-drying process, which helps to improve the freeze-drying efficiency and the quality of the freeze-dried product. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The above and other purposes, features, and advantages of the present application will become more apparent through a more detailed description of the embodiments of the present application in conjunction with the accompanying drawings. The accompanying drawings are intended to provide a further understanding of the embodiments of the present application and constitute a part of the specification. Together with the embodiments of the present application, they are used to explain the present application and do not constitute a limitation of the present application. In the drawings, the same reference numerals generally represent the same components or steps.

[0020] Figure 1 The figure shows a schematic structural diagram of the double-chamber cartridge 1 of the present application.

[0021] Figure 2 The figure shows a schematic structural diagram of the plug assembly of the present application.

[0022] Figure 3 The figure shows a schematic structural diagram of the top cover 4 of the present application.

[0023] Description of Reference Numerals

[0024] 1-Dual-chamber cartridge 3-Top stopper 4-Top cover 10-Bottle mouth

[0025] 11- Bottle neck 12- Bottle body 13- Inner cavity 20- Holding fixture

[0026] 21- press-in fixture 30- plug cap 31- plug plunger 41- chassis

[0027] 100-bottle opening 120-bypass 200-protrusion 210-pressure column

[0028] 400-top plate 401-annular thread DETAILED DESCRIPTION

[0029] The present application discloses a bottle cap assembly, wherein the bottle cap assembly includes a top plug 3 and a top cover 4, which are used to seal a double-chamber cartridge 1. In particular, the double-chamber cartridge 1 can be placed in a freeze-drying rack used in existing freeze-drying processes, and when the double-chamber cartridge 1 is fixed with the bottle cap assembly and placed in the freeze-drying rack, the bottle cap assembly can also be adapted to be placed in a freeze-drying rack used in existing freeze-drying processes; the bottle cap assembly can be made of any material that is adapted to achieve the bottle cap sealing function. The top plug 3 is used to seal the bottle mouth 10 of the double-chamber cartridge 1. The top plug 3 is pressed by the pressing plug assembly to engage with the double-chamber cartridge 1 to achieve sealing of the double-chamber cartridge 1; when the pressing plug assembly presses the top plug 3, the pressing plug assembly can be driven by mechanical compression, air pressure drive, pneumatic clamp drive, or spring pressure.

[0030] The top cap 4 disclosed in the present application is used to fix the top plug 3 and seal the bottle mouth 10 of the dual-chamber cartridge 1; wherein, the plug pressing assembly includes a pressing jig 21 and a retaining jig 20. When the top plug 3 is pressed by the plug pressing assembly and thus engaged with the dual-chamber cartridge 1, the sealing of the dual-chamber cartridge 1 can be achieved by the mutual cooperation of the retaining jig 20 and the pressing jig 21 of the plug pressing assembly. The specific cooperation method can be:

[0031] The top plug 3 is positioned relative to the mouth 10 of the dual-chamber cartridge 1 by placing the retaining jig 20 in contact with the outer wall of the mouth 10 of the dual-chamber cartridge 1; the top plug 3 is pressed into place by the pressing jig 21 to engage the top plug 3 within the mouth 10 of the dual-chamber cartridge 1; and the pressing jig 21 and retaining jig 20 are removed. It should be noted that if the dimensions of part or all of the structure of the dual-chamber cartridge 1 change, the dimensions of the top plug 3, the pressing jig 21, and the retaining jig 20 can also be adjusted accordingly to adapt to the dimensions of the dual-chamber cartridge 1 and complete the sealing of the mouth.

[0032] In the present application, a dual-chamber cartridge 1 comprises an inner chamber 13, a body 12, a neck 11, and a mouth 10. A mouth opening 100 is centrally located at the mouth 10, connected to the inner chamber 13. The inner diameter of the mouth opening 100 is smaller than the inner diameters of the mouth 10 and the neck 11. A bypass 120 is provided on one outer wall of the body 12. Those skilled in the art will appreciate that the dimensions of the inner chamber 13, body 12, neck 11, and mouth 10 of the dual-chamber cartridge 1 can be adjusted within a dimensional range suitable for placement in a freeze-drying rack without altering its intended function. For example, increasing the vertical length of one or more portions of the dual-chamber cartridge 1 or increasing the radial length of one or more portions of the dual-chamber cartridge 1 does not deviate from the scope of protection of the present application.

[0033] When the dual-chamber cartridge 1 is placed on the freeze-drying rack, the upper opening of the freeze-drying rack is larger than the bottom opening. Therefore, the upper opening facilitates the insertion of the bypass 120, while the lower opening can properly secure the dual-chamber cartridge 1, preventing it from falling out of the fixing module, thereby preventing the dual-chamber cartridge 1 from tipping over during the freeze-drying process.

[0034] In the present application, the top plug 3 includes a plug cap 30 and a plug 31. The diameter of the plug 31 is slightly larger than the inner diameter of the bottle opening 100 of the bottle mouth 10. After the plug 31 is inserted into the bottle opening 100, the lower surface of the plug cap 30 completely conforms to the upper surface of the bottle mouth 10. In particular, the diameter of the plug 31 can be adjusted within the diameter range of the bottle opening 100 within which the plug 31 is pressed and inserted, and the diameter of the plug 31 cannot be less than or equal to the diameter of the bottle opening 100.

[0035] In the present application, the pressing jig 21 is a cylinder having an opening at the bottom and a depression at the center of the upper surface; further, a protruding pressing column 210 may be provided on the lower inner wall of the depression at the center of the upper surface of the pressing jig 21, facing the lower opening. When the top plug 3 moves toward the bottle mouth 10, the upper surface of the pressing jig 21 presses the top plug 3 toward the bottle mouth 10. Specifically, the depression at the center of the upper surface of the pressing jig 21 presses the top plug 3 toward the bottle mouth 10 so that the top plug 3 is embedded in the bottle mouth 10; when a pressing column 210 is provided on the lower inner wall of the upper surface of the pressing jig 21, the pressing column 210 presses the top plug 3 toward the bottle mouth 10 so that the top plug 3 is embedded in the bottle mouth 10. The pressing jig 21 may be a cylinder or a prism, and the shape of the pressing column 210 may be a cylinder, a prism, or an ellipsoid. The contact surface between the pressing column 210 and the plug cap 30 of the top plug 3 may be a plane or a curved surface.

[0036] The number of pressure pins 210 is two, three, or more. Specifically, all pressure pins 210 are arranged centrally, axially, or evenly spaced along the center of the lower inner wall of the pressing jig 21, thereby ensuring a uniform distribution of the pressure pins 210 on the lower inner wall of the pressing jig 21. This ensures that as the top plug 3 moves toward the bottle mouth 10, the pressure pins 210 provide uniform downward pressure on the stopper cap 30, ensuring that the top plug 3, positioned by the holding jig 20, fits horizontally into the bottle mouth 10. This prevents the edge of the top plug 3 from warping or indenting during the insertion process, thereby helping to maintain the accuracy of the pressing.

[0037] In the present application, the holding jig 20 is configured such that its inner wall fits against the bottle mouth 10 and the bottle body 11, and its upper end protrudes from the bottle mouth 10; and when the top plug 3 moves toward the bottle mouth 10, the inner wall of the pressing jig 21 fits against and slides against at least a portion of the outer wall of the holding jig 20. The length of the upper end of the holding jig 20 protruding from the bottle mouth 10 can be no less than the length of the top plug 3 restrained by the protrusion 200, or it can be less than the length of the top plug 3 restrained by the protrusion 200. When the length of the upper end of the holding jig 20 protruding from the bottle mouth 10 can be greater than the length of the top plug 3 restrained by the protrusion 200, the holding jig 20 can protect the top plug 3, preventing the top plug 3 from slipping off or popping out of the holding jig 20 during the plugging process, thereby improving the plugging stability.

[0038] In the present application, the retaining fixture 20 is further provided with a raised portion 200. The raised portion 200 supports and secures the top plug 3 before the top plug 3 is inserted into the bottle mouth 10, so that the plug 31 is aligned with the bottle mouth opening 100 of the bottle mouth 10; and the raised portion 200 secures the top plug 3 after the top plug 3 is inserted into the bottle mouth 10. It will be understood by those skilled in the art that the raised portion 200 will not significantly hinder the movement of the top plug 3 during the insertion of the top plug 3 into the bottle mouth 10. Since the raised portions 200 are evenly distributed on the inner wall of the retaining fixture 20, and the pressure column 210 uniformly applies pressure to the plug cap 30, the top plug 3 will be horizontally inserted into the bottle mouth 10 without being subjected to a larger or smaller force component in any direction. The shape of the raised portion 200 can be trapezoidal, semicircular, semi-elliptical, or rectangular, and its contact surface with the side of the plug cap 30 of the top plug 3 can be flat or curved.

[0039] In the present application, the number of raised portions 200 is two or three or more. It should be noted that the raised portions 200 extend radially along the retaining jig 20 and are evenly spaced circumferentially on the inner wall of the retaining jig 20. The number of raised portions 200 and the length / radian of the intervals between the multiple raised portions 200 can be adjusted to maintain optimal positioning and securing of the top plug 3.

[0040] In this application, the top cap 4 comprises a main body and a bottom plate 41. The main body has a top plate 400 and an annular thread 401. The inner wall of the top cap 4 mates with the bottle mouth 10 and the neck 11; the bottom plate 41 of the top cap 4 completely mates with the upper surface of the bottle body 12. After the top cap 4 has sealed the bottle mouth 10 of the dual-chamber cartridge 1, the top plate 400 is positioned to mate with the stopper cap 30 to press the stopper 3 in place. The annular thread 401 is designed to threadably engage with a sterile injection needle.

[0041] The present application also discloses a dual-chamber cartridge packaging material for injection, comprising the aforementioned bottle cap assembly and a dual-chamber cartridge 1. It should be noted that the dual-chamber cartridge packaging material for injection may include any combination of the bottle cap assembly and the dual-chamber cartridge 1 formed and / or retained by any combination disclosed in the present application.

[0042] Currently, the vast majority of freeze-dried products on the market use vials as drug containers. Before injection, a sterile syringe must be used to extract the reconstitution solvent from another container containing the reconstitution solvent. The reconstitution solvent must then be injected into the drug container for reconstitution, extraction, and administration. This results in relatively poor dosing accuracy and compliance. However, the bottle cap assembly and dual-chamber cartridge packaging material of the present application can effectively utilize the front chamber to hold the freeze-dried drug and the rear chamber to hold the reconstitution solvent. Furthermore, during use, the reconstitution solvent can be bypassed by pushing the bottom plug into the front chamber to reconstitute the freeze-dried drug, eliminating the need for multiple extractions. This greatly improves the ease of use for subjects or patients, enabling self-injection by the subject or patient.

[0043] On the other hand, the bottle cap assembly of the present application can also complete the plug sealing of the dual-chamber cartridge in the freeze dryer, maintaining the low moisture content of the freeze-dried product, thereby maintaining the quality stability of the product. Therefore, the bottle cap assembly and the dual-chamber cartridge of the present application can be used to prepare and store a variety of pharmaceutical preparations, medical beauty products, and cosmetics such as insulin, growth factors, vaccines, chemotherapy drugs, hormone drugs, facial fillers, hyaluronic acid injections, facial essences, and customized perfumes, thereby improving the application prospects and application scope of the above-mentioned products prepared by the freeze-drying process.

[0044] Example

[0045] This utility model provides a general and / or specific description of the materials and test methods used in the experiment. The reagents or instruments used without indicating the manufacturer are all conventional reagent products that can be purchased from the market.

[0046] A bottle cap assembly includes a top plug 3 and a top cover 4 for sealing a double-chamber cartridge bottle 1. The structure of the double-chamber cartridge bottle 1 is as follows: Figure 1 As shown, the top plug 3 is used to seal the bottle mouth of the double-chamber cartridge bottle 1. The double-chamber cartridge bottle 1 uses a pressing plug assembly to achieve the sealing of the bottle mouth 10 by the top plug 3, wherein the pressing plug assembly includes a pressing fixture 21 and a holding fixture 20, and its structure is as shown in FIG. Figure 2 As shown, the double-chamber cartridge bottle 1 comprises a bottle mouth 10, a bottle neck 11, a bottle body 12, and an inner cavity 13 extending from the bottle mouth to the bottle body; the top plug comprises a plug cap 30 and a plug rod 31. The plug rod 31 needs to be completely embedded in the opening 100 at the center of the bottle mouth 10, and the lower surface of the plug cap 30 needs to be completely in contact with the upper surface of the bottle mouth 10 to achieve sealing of the bottle mouth 10.

[0047] Therefore, in this embodiment, the plugging assembly is used to seal the bottle mouth 10 using the top plug 3. Specifically,

[0048] (1) First, the plugging assembly includes a holding jig 20, the upper and lower ends of which are both open. The inner wall of the holding jig 20 is pressed against the outer surface of the bottle mouth 10 and the bottle body 12, and the holding jig 20 is pressed until it is completely in contact with the upper end of the bottle body 12. The holding jig 20 is tightly fitted with the bottle mouth 10 and the bottle body 12, and has a large friction force. Therefore, the holding jig 20 is not easy to fall off from the double-chamber cartridge bottle 1; in addition, the upper end of the holding jig 20 protrudes from the bottle mouth 10.

[0049] Next, the top plug 3 is placed in the holding jig 20. Specifically, the top plug is placed on a raised portion 200 protruding from the upper end of the holding jig 20. The raised portion 200 supports the cap 30 to secure the top plug 3 in place, aligning the plug 31 with the bottle opening 100. This facilitates the plug 31's insertion into the bottle opening 100 as it moves downward. Specifically, there are two raised portions 200, one on each side of the upper end of the holding jig 20.

[0050] Then, the inner wall of the pressing jig 21 of the plug assembly is fitted against the outer wall of the retaining jig 20 and slid downward. The lower end of the pressing jig 21 is open, the upper surface is closed and the center is concave downward. A pressing column 210 protruding along the axial direction of the pressing jig 21 is provided on one side of the inner wall of the concave part. During the downward sliding of the pressing jig 21, the pressing column 210 can contact and apply downward pressure to the plug cap 30 to press the top plug 3 as a whole to move toward the bottle mouth 10 until the plug column 31 is fully embedded in the bottle mouth 10; after the plug column 31 is fully embedded in the bottle mouth 10, the plug cap 30 can be just clamped at the lower end of the protrusion 200, so that the protrusion 200 can further clamp the top plug 3 to prevent it from falling off. It is important to note that before the plug 31 is fully embedded in the bottle mouth 10, the height of the retaining jig 20 protruding from the bottle mouth 10 is less than the height of the outer side of the upper surface of the pressing jig 21 protruding from the bottle mouth 10. Therefore, before the plug 31 is fully embedded in the bottle mouth 10, the pressing jig 21 is not hindered by the retaining jig 20 from moving downward, thus preventing the top plug 3 from being incompletely engaged with the bottle mouth 10. In particular, there are two pressing columns 210, one on each side of the inner wall of the recessed portion of the upper surface of the pressing jig 21, to apply uniform downward pressure to the top plug 3.

[0051] Finally, the pressing jig 21 and the holding jig 20 are removed. The plugging assembly is only used to seal the bottle mouth 10 using the top plug 3. Therefore, it needs to be removed after the sealing is completed to facilitate the subsequent capping and sealing.

[0052] (2) Use the top cover 4 to fix the top plug 3 and seal the bottle mouth 10 of the double-chamber cartridge 1 through the top plug 3. The structure of the top cover 4 is as follows: Figure 3 As shown, it includes a main body and a bottom plate 41. The main body has a top plate 400 located at the center of the upper end of the top cover 4 and an annular thread 401 located at the edge of the upper end of the top cover 4, which is arranged above the bottom plate 41, and the bottom of the bottom plate 41 is an opening. After the top plug 3 is completely embedded in the bottle mouth 10, the top cover 4 is pressed downward and put on the bottle mouth 10. During this process, the inner walls of the main body and the bottom plate 41 are in contact with the bottle mouth 10 and the neck 11. Therefore, after the top cover 4 is pressed until the bottom plate 41 is completely in contact with the upper surface of the bottle body 12, there is a large friction between the top cover 4 and the dual-chamber cartridge 1, which can prevent the top cover 4 from falling off, thereby improving the sealing performance of the dual-chamber cartridge 1.

[0053] The top plate 400 has a double-layer structure, wherein the upper layer is a hollow cylinder and the lower layer is a cylinder having an inner diameter equal to the inner diameter of the hollow portion of the upper hollow cylinder. After the bottom plate 41 is completely in contact with the upper surface of the bottle body 12, the top plate 400 can support the top plug 3 embedded in the bottle mouth 10 through the lower cylinder to prevent the top plug 3 from falling out of the bottle mouth 10, thereby improving the airtightness of the double-chamber cartridge bottle 1.

Claims

1. A bottle cap assembly, characterized in that: The bottle cap assembly is used to seal a double-chamber cartridge bottle (1). The bottle cap assembly comprises a top plug (3) and a top cover (4); The top plug (3) seals the bottle mouth (10) of the double-chamber cartridge bottle (1); The top plug (3) is pressed by the plug pressing assembly to engage with the double-chamber cartridge bottle (1) to achieve sealing of the double-chamber cartridge bottle (1); The top cover (4) is used to fix the top plug (3) and seal the bottle mouth (10) of the double-chamber cartridge bottle (1); The plugging assembly comprises a pressing jig (21) and a retaining jig (20).

2. The bottle cap assembly according to claim 1, wherein: in, The double-chamber cartridge bottle (1) comprises: an inner cavity (13), a bottle body (12), a bottle neck (11) and a bottle mouth (10); a bottle mouth opening (100) connected to the inner cavity (13) is provided at the center of the bottle mouth (10); the inner diameter of the bottle mouth opening (100) is smaller than the inner diameters of the bottle mouth (10) and the bottle neck (11); One side outer wall of the bottle body (12) is provided with a bypass (120).

3. The bottle cap assembly according to claim 2, wherein: in, The top plug (3) comprises a plug cap (30) and a plug rod (31); the diameter of the plug rod (31) is slightly larger than the inner diameter of the bottle mouth opening (100) of the bottle mouth (10); after the plug rod (31) is embedded in the bottle mouth opening (100), the lower surface of the plug cap (30) is completely in contact with the upper surface of the bottle mouth (10).

4. The bottle cap assembly according to claim 3, wherein: in, The press-in jig (21) is a column with an opening at the bottom and a depression at the center of the upper surface; When the top plug (3) moves toward the bottle mouth (10), the lower surface of the pressing jig (21) presses the top plug (3) toward the bottle mouth (10), so that the top plug (3) is embedded in the bottle mouth (10).

5. The bottle cap assembly according to claim 4, characterized in that: in, The holding fixture (20) is configured such that its inner wall fits the bottle mouth (10) and the bottle body (12), and its upper end protrudes from the bottle mouth (10); and When the top plug (3) moves toward the bottle mouth (10), the inner wall of the pressing jig (21) adheres to and slides against the outer wall of at least a portion of the holding jig (20).

6. The bottle cap assembly according to claim 5, wherein: in, The holding fixture (20) is further provided with a protrusion (200), and the protrusion (200) supports and fixes the top plug (3) before the top plug (3) is inserted into the bottle mouth (10), so that the plug (31) is aligned with the bottle mouth opening (100) of the bottle mouth (10); and The raised portion (200) secures the top plug (3) after the top plug (3) is embedded in the bottle mouth (10).

7. The bottle cap assembly according to claim 6, wherein: in, The number of the protrusions (200) is two or three or more.

8. The bottle cap assembly according to claim 2, wherein: in, The top cover (4) comprises a main body and a bottom plate (41), the main body having a top plate (400) and an annular thread (401), and the inner wall of the top cover (4) is in contact with the bottle mouth (10) and the bottle neck (11); and The bottom plate (41) of the top cover (4) is completely in contact with the upper surface of the bottle body (12).

9. A double-chamber cartridge packaging material for injection, characterized in that: The double-chamber cartridge bottle packaging material for injection comprises a bottle cap assembly according to any one of claims 1 to 8 and a double-chamber cartridge bottle (1).

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