Resin extraction and separation device for urokinase preparation

Abstract

The utility model relates to the field of resin extraction and separation, and discloses a resin extraction and separation device for urokinase preparation, which comprises a separation box, the inner wall of the upper end of the separation box is fixedly connected with a partition plate, the outer wall of the bottom end of the partition plate is fixedly connected with a filter plate, and the inner wall of the upper end of the separation box is rotatably connected with a rotating pipe in a penetrating manner; a fixed pipe is rotationally connected to the inner wall of the upper end of the rotating pipe, and a stirring box is fixedly connected to the outer wall of the upper end of the fixed pipe. According to the urine and resin filtering device, fixing of the rotating pipe is relieved by moving the embedded block, after the rotating pipe is rotated by 180 degrees, the embedded block is released to be clamped on the inner wall of the fixed pipe to fix the position of the rotating pipe, and at the moment, a mixture of urine and resin flows to the other side to be continuously filtered; and then the collection box is removed by rotating the clamping block, the collection box is taken out, resin separation is completed, continuous resin extraction and separation can be achieved, and the separation efficiency is high.

Description

Technical Field

[0001] The utility model relates to the field of resin extraction and separation, in particular to a resin extraction and separation device for preparing urokinase. Background Art

[0002] Urokinase is an important drug. Urokinase is a serine protease that can specifically hydrolyze fibrin, thereby dissolving blood clots.

[0003] In the preparation of urokinase, the urine after precipitation treatment needs to be separated by a resin extraction and separation device. After the urine and resin are mixed in a stirring box, they flow into a separation box. Under the action of the filter plate, the resin adsorbs urokinase, and the urine flows out through the filter plate.

[0004] When separating resin and urine in an existing resin extraction and separation device for preparing urokinase, it is usually necessary to close the bottom valve of the stirring box after the collection box is full of resin to stop the resin and urine mixture from entering the separation box. After replacing the collection box, the valve is opened to continue the separation operation, resulting in low separation efficiency. Therefore, a resin extraction and separation device for preparing urokinase is proposed to solve the above problem. Utility Model Content

[0005] In order to make up for the above shortcomings, the utility model provides a resin extraction and separation device for the preparation of urokinase, which aims to improve the problem of low separation efficiency in the prior art in which after the collection box is full of resin, the bottom valve of the stirring box needs to be closed to stop the mixture of resin and urine from entering the separation box, and the valve needs to be opened after the collection box is replaced to continue the separation operation.

[0006] In order to achieve the above-mentioned purpose, the utility model adopts the following technical solution: a resin extraction and separation device for preparing urokinase.

[0007] As a further description of the above technical solution:

[0008] The collecting assembly includes a collecting box, the outer wall of which is slidably connected to the front inner wall of the separation box, a filter is detachably installed on the upper inner wall of the collecting box, a baffle is elastically connected to the rear inner wall of the collecting box through a spring, a fixing bar 1 is fixedly connected to the rear outer wall of the baffle, a fixing bar 2 is fixedly connected to the upper inner wall of the separation box, and a blocking block is provided on the front outer wall of the separation box.

[0009] As a further description of the above technical solution:

[0010] The limiting component includes an insert, and the rear outer wall of the insert is elastically connected to the front inner wall of the rotating tube through a second spring.

[0011] As a further description of the above technical solution:

[0012] One end of the spring 1 is fixedly connected to the rear end inner wall of the collection box, and the other end of the spring 1 is fixedly connected to the upper end outer wall of the baffle.

[0013] As a further description of the above technical solution:

[0014] The outer wall of the baffle is slidably connected to the rear end inner wall of the collection box.

[0015] As a further description of the above technical solution:

[0016] One end of the second spring is fixedly connected to the front end outer wall of the rotating tube, and the other end of the second spring is fixedly connected to the rear side outer wall of the insert.

[0017] As a further description of the above technical solution:

[0018] The rear outer wall of the insert penetrates and is slidably connected to the front inner wall of the rotating tube, and the rear outer wall of the insert is clamped on the front inner wall of the fixed tube.

[0019] As a further description of the above technical solution:

[0020] The front end outer wall of the second fixing bar is arranged in an inclined shape.

[0021] The utility model has the following beneficial effects:

[0022] 1. In the present invention, the fixing of the rotating tube is released by moving the insert, and after the rotating tube is rotated 180 degrees, the insert is released and connected to the inner wall of the fixed tube to fix the position of the rotating tube. At this time, the mixture of urine and resin flows to the other side for continued filtration. The collecting box is finally removed by rotating the card block to complete the separation of the resin, thereby realizing continuous resin extraction and separation with high separation efficiency.

[0023] 2. In the present invention, when the collection box is moved backward into the front inner wall of the separation box, the rear end inclined surface of the fixing strip 1 at the rear end of the baffle is squeezed by the fixing strip 2 and moves upward, squeezing the spring 1 to open the rear end opening of the collection box. A filter is provided in the collection box to separate the urine remaining on the resin falling into the collection box, thereby reducing the urine residue on the collected resin. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 This is a three-dimensional schematic diagram of a resin extraction and separation device for preparing urokinase proposed in the present invention;

[0025] Figure 2 This is a cross-sectional schematic diagram of a separation box of a resin extraction and separation device for preparing urokinase proposed in the present invention;

[0026] Figure 3 This is a cross-sectional diagram of a rotating tube of a resin extraction and separation device for preparing urokinase proposed in the present invention;

[0027] Figure 4 This is a schematic diagram of a collection box of a resin extraction and separation device for urokinase preparation proposed in the present invention;

[0028] Figure 5 The utility model proposes a resin extraction and separation device for urokinase preparation Figure 4 A magnified schematic diagram of .

[0029] Legend:

[0030] 1. Separation box; 2. Rotating tube; 3. Fixed tube; 4. Mixing box; 5. Collecting box; 6. Filter plate; 7. Filter screen; 8. Second fixing bar; 9. Insert; 10. Inclined plate; 11. Second spring; 12. First fixing bar; 13. Baffle; 14. First spring; 15. Partition; 16. Block. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0032] Reference Figure 1-Figure 3The utility model provides an embodiment: a resin extraction and separation device for preparing urokinase, comprising a separation box 1, the separation box 1 is used to separate resin and urine, a partition 15 is fixedly connected to the inner wall of the upper end of the separation box 1, the partition 15 plays a separating role, the setting of the partition 15 divides the separation box 1 into two parts, which can be continuously filtered, a filter plate 6 is fixedly connected to the outer wall of the bottom end of the partition 15, the filter plate 6 is arranged in an inclined shape, the filter plate 6 is used to separate resin and urine, a rotating tube 2 is passed through and rotatably connected to the inner wall of the upper end of the separation box 1, the rotation of the rotating tube 2 is used to change the flow direction of the urine and resin mixture, and a fixed filter is rotatably connected to the inner wall of the upper end of the rotating tube 2. Tube 3, the fixed tube 3 plays a connecting role, which is used to connect the bottom opening of the stirring box 4 with the rotating tube 2. The stirring box 4 is fixedly connected to the outer wall of the upper end of the fixed tube 3. The stirring box 4 is used for stirring urine and resin. The stirring box 4 is a prior art. A limiting component is provided on the front inner wall of the rotating tube 2. The limiting component is used to limit the rotating tube 2. An inclined plate 10 is fixedly connected to the inner wall of the bottom end of the rotating tube 2. The upper outer wall of the inclined plate 10 is inclined, which guides the mixture of urine and resin. The bottom outer wall of the inclined plate 10 is rotatably connected to the upper inner wall of the partition 15. A collecting component is provided on the front inner wall of the separation box 1, and the collecting component is used for collecting resin.

[0033] Reference Figure 2 、 Figure 4 and Figure 5 The collecting assembly includes a collecting box 5, which is provided with two collecting boxes 5. The collecting box 5 is configured to collect the filtered resin. The outer wall of the collecting box 5 is slidably connected to the front inner wall of the separation box 1. A filter screen 7 is detachably installed on the inner wall of the upper end of the collecting box 5. The filter screen 7 is configured to filter out the urine on the resin surface falling into the collecting box 5 again to reduce the urine residue on the resin surface. A baffle 13 is elastically connected to the inner wall of the rear end of the collecting box 5 through a spring 14. The baffle 13 is configured to close the rear end opening of the collecting box 5. When the collecting box 5 moves backward into the front inner wall of the separation box 1, the rear end inclined surface of the fixing bar 12 at the rear end of the baffle 13 is squeezed by the fixing bar 2 8 and moves upward, squeezing the spring 14 to open the rear end opening of the collecting box 5. To facilitate the discharge of urine in the collection box 5 into the separation box 1, the outer wall of the baffle 13 is slidably connected to the rear end inner wall of the collection box 5, one end of the spring 14 is fixedly connected to the rear end inner wall of the collection box 5, and the other end of the spring 14 is fixedly connected to the upper end outer wall of the baffle 13. A fixing bar 12 is fixedly connected to the rear end outer wall of the baffle 13, and the rear end outer wall of the fixing bar 12 is inclined. A fixing bar 2 8 is fixedly connected to the upper end inner wall of the separation box 1, and the front end outer wall of the fixing bar 2 8 is inclined. A card block 16 is provided on the front end outer wall of the separation box 1, and the card block 16 is rotatable. By rotating the card block 16 ninety degrees, the collection box 5 can be moved into the separation box 1, and releasing the card block 16 to return to its original position allows the collection box 5 to be fixed in the separation box 1.

[0034] Reference Figure 3 The limiting assembly includes an insert 9, and the rear outer wall of the insert 9 is clamped on the front inner wall of the fixed tube 3 to fix the position of the rotating tube 2. When the rear outer wall of the insert 9 leaves the front inner wall of the fixed tube 3, the fixation of the rotating tube 2 can be released. The rear outer wall of the insert 9 passes through and is slidably connected to the front inner wall of the rotating tube 2. The rear outer wall of the insert 9 is clamped on the front inner wall of the fixed tube 3. The rear outer wall of the insert 9 is elastically connected to the front inner wall of the rotating tube 2 through a spring 2 11. One end of the spring 2 11 is fixedly connected to the front outer wall of the rotating tube 2, and the other end of the spring 2 11 is fixedly connected to the rear outer wall of the insert 9.

[0035] Working principle: By rotating the block 16 and rotating the block 16 ninety degrees, the collection box 5 can be moved into the separation box 1. When the collection box 5 moves backward to the front inner wall of the separation box 1, the rear end inclined surface of the fixing bar 12 at the rear end of the baffle 13 is squeezed by the fixing bar 2 8 and moves upward, squeezing the spring 14 to open the rear end opening of the collection box 5, releasing the block 16 to return to its original position so that the collection box 5 is fixed in the separation box 1. The stirring box 4 is used to fully stir the resin and urine. The stirred mixture of resin and urine enters the separation box 1 through the fixed tube 3 and the rotating tube 2. The mixture of resin and urine entering the separation box 1 is filtered by the filter plate 6. , so that urine passes through the filter plate 6 and enters the bottom end of the separation box 1 for discharge, and the resin passes through the inclined filter plate 6 and enters the collection box 5. The urine remaining on the resin falling into the collection box 5 passes through the filter screen 7 and the rear end opening in the collection box 5 and enters the bottom end of the separation box 1 for discharge. When the collection box 5 on one side completes the collection, the fixing of the rotating tube 2 is released by moving the insert 9, and the rotating tube 2 is rotated 180 degrees and then the insert 9 is released to fix the rotating tube 2 on the inner wall of the fixed tube 3. At this time, the mixture of urine and resin flows to the other side for continued filtration, and then the collection box 5 is removed by rotating the clamping block 16 to complete the separation of the resin.

[0036] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A resin extraction and separation device for preparing urokinase, comprising a separation box (1), characterized in that: A partition (15) is fixedly connected to the inner wall of the upper end of the separation box (1), and a filter plate (6) is fixedly connected to the outer wall of the bottom end of the partition (15). A rotating tube (2) is passed through and rotatably connected to the inner wall of the upper end of the separation box (1). A fixed tube (3) is rotatably connected to the inner wall of the upper end of the rotating tube (2). A stirring box (4) is fixedly connected to the outer wall of the upper end of the fixed tube (3). A limiting component is provided on the inner wall of the front end of the rotating tube (2), and the limiting component is used to limit the rotating tube (2). An inclined plate (10) is fixedly connected to the inner wall of the bottom end of the rotating tube (2). A collecting component is provided on the inner wall of the front end of the separation box (1), and the collecting component is used to collect resin.

2. The resin extraction and separation device for preparing urokinase according to claim 1, characterized in that: The collecting assembly comprises a collecting box (5), the outer wall of the collecting box (5) is slidably connected to the front inner wall of the separation box (1), a filter (7) is detachably mounted on the upper inner wall of the collecting box (5), a baffle (13) is elastically connected to the rear inner wall of the collecting box (5) via a spring (14), a fixing bar (12) is fixedly connected to the rear outer wall of the baffle (13), a fixing bar (8) is fixedly connected to the upper inner wall of the separation box (1), and a clamping block (16) is provided on the front outer wall of the separation box (1).

3. The resin extraction and separation device for preparing urokinase according to claim 1, characterized in that: The limiting assembly comprises an insert (9), the rear outer wall of the insert (9) being elastically connected to the front inner wall of the rotating tube (2) via a second spring (11).

4. The resin extraction and separation device for preparing urokinase according to claim 2, characterized in that: One end of the spring (14) is fixedly connected to the rear end inner wall of the collection box (5), and the other end of the spring (14) is fixedly connected to the upper end outer wall of the baffle (13).

5. The resin extraction and separation device for preparing urokinase according to claim 2, characterized in that: The outer wall of the baffle (13) is slidably connected to the rear end inner wall of the collection box (5).

6. The resin extraction and separation device for preparing urokinase according to claim 3, characterized in that: One end of the second spring (11) is fixedly connected to the front end outer wall of the rotating tube (2), and the other end of the second spring (11) is fixedly connected to the rear side outer wall of the insert (9).

7. The resin extraction and separation device for preparing urokinase according to claim 3, characterized in that: The rear outer wall of the insert (9) penetrates and is slidably connected to the front inner wall of the rotating tube (2), and the rear outer wall of the insert (9) is clamped on the front inner wall of the fixed tube (3).

8. The resin extraction and separation device for preparing urokinase according to claim 2, characterized in that: The front end outer wall of the second fixing strip (8) is arranged in an inclined shape.

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