Magnetic stirring device of bioreactor

Abstract

The utility model discloses a magnetic stirring device of a bioreactor, which belongs to the field of bioreactors and comprises a moving plate, universal wheels are arranged at angles of the bottom of the moving plate, a control box is arranged on the rear side of the upper surface of the moving plate, and a control panel is arranged on one side of the top of the control box. A stand column is vertically fixed to the upper surface of the movable plate, a lifting supporting arm is vertically and slidably installed at the top of the stand column and extends forwards, an extending supporting plate is arranged on the surface of the front side of the stand column, a reaction container is fixed to the front end of the extending supporting plate, and a driving motor is installed at the front end of the lifting supporting arm; the driving motor is arranged right above the reaction container, a plurality of sensor cables and sampling tubes penetrate through surface through holes of the stand columns and are connected to the control box, and the outer sides of the stand columns can control the extrusion bolts to extrude and fix the cables through the elastic plates, so that the cables are prevented from falling off, and the stability of cable connection is improved.

Description

Technical Field

[0001] The utility model relates to the field of bioreactors, and more particularly to a magnetic stirring device for a bioreactor. Background Art

[0002] A bioreactor is a device system that utilizes the biological functions of enzymes or organisms (such as microorganisms) to obtain target products through biochemical reactions or the metabolism of the organism itself in vitro or in vivo. The bioreactor provides suitable environmental conditions for the metabolic activities of organisms, such as suitable temperature, pH value, dissolved oxygen content, etc., so that the organisms can carry out normal physiological activities and biochemical reactions therein, thereby converting substrates into target products. In order to ensure sufficient reaction of substances inside the reactor, the medium inside the reactor will be stirred. Common bioreactors mostly use magnetic stirring and stirrers driven by magnetic couplers. During use, since the bioreactor is in a sealed state, various sensors are required to monitor the internal substances, and multiple sensors are connected to multiple cables, which leads to confusion in the internal circuit of the reactor and is prone to confusion during connection and installation. Utility Model Content

[0003] 1. Technical problems to be solved

[0004] In view of the problems existing in the prior art, the purpose of the present invention is to provide a magnetic stirring device for a bioreactor, which can comb the sensor wires to ensure the neatness of the circuits.

[0005] 2. Technical solution

[0006] In order to solve the above problems, the present invention adopts the following technical solutions.

[0007] The lifting mechanism is a lifting mechanism that lifts up and down of described lifting mechanism, and the lifting mechanism is lifted and lowered out of the lifting mechanism, and the lifting mechanism is lifted and lowered out of the lifting mechanism.

[0008] Furthermore, an elastic sheet is provided on one side of the column, a locking bolt passes through the rear end of the elastic sheet, the locking bolt is screwed onto the column, and the elastic sheet extends beyond the front surface of the column.

[0009] Furthermore, a track groove is provided on the surface of the elastic sheet, the extrusion bolt passes through the track groove, and a concave ring is provided on the end of the surface of the extrusion bolt away from the through hole, and the concave ring is adapted to the track groove.

[0010] Furthermore, a boss is provided on the front surface of the column, and a screw rod is passed through the inner side of the boss through horizontal screw thread engagement, and the screw rod is placed between two adjacent through holes.

[0011] Furthermore, a knob is provided at one end of the screw, and a push rod is installed at the other end of the screw through a bearing. The push rod is vertically arranged and vertically spans the inner sides of multiple elastic sheets, and the push rod corresponds to the protruding part of the elastic sheet.

[0012] Furthermore, the bottom of the reaction container is symmetrically connected to a floor drain pipe, and the surface of the reaction container is symmetrically provided with observation windows.

[0013] Furthermore, the four docking joints correspond to one sampling tube and three sensors respectively.

[0014] 3. Beneficial effects

[0015] Compared with the existing technology, the advantages of the present invention are: the present invention provides a magnetic stirring device for a bioreactor, multiple sensor cables and sampling tubes are inserted through the through holes of the column and connected to the control box, and the elastic plate on the outside of the column can control the squeezing bolt to squeeze and fix the cable to prevent the cable from falling off, improve the stability of the cable connection, and at the same time comb multiple cables to prevent the problem of connection misalignment caused by cable confusion. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a schematic diagram of the installation three-dimensional structure of the utility model;

[0017] Figure 2 For the utility model Figure 1 Schematic diagram of the enlarged structure of area A;

[0018] Figure 3 This is a schematic diagram of the three-dimensional structure of the elastic sheet and the extrusion bolt installation of the utility model.

[0019] Explanation of the numbers in the figure: 1. Moving plate; 2. Control box; 201. Control panel; 3. Column; 301. Through hole; 302. Boss; 4. Extended support plate; 5. Lifting support arm; 6. Drive motor; 7. Reaction vessel; 701. Observation window; 702. Groove; 703. Butt joint; 8. Floor drain pipe; 9. Extrusion bolt; 901. Arc surface; 902. Concave ring; 10. Elastic sheet; 101. Track groove; 11. Locking bolt; 12. Screw; 121. Knob; 13. Push rod. DETAILED DESCRIPTION

[0020] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention; it is obvious that the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0021] Example:

[0022] See also Figure 1-Figure 3 As shown, a magnetic stirring device for a bioreactor includes a movable plate 1. Universal wheels are provided at the bottom angles of the movable plate 1 to facilitate the movement of the device and improve the flexibility of the device. A control box 2 is provided on the rear side of the upper surface of the movable plate 1. The control box 2 can control the speed of the stirring paddle, the internal temperature of the reaction vessel 7, and monitor various internal data. A control panel 201 is provided on one side of the top of the control box 2 for easy operation. A column 3 is vertically fixed to the upper surface of the movable plate 1. The column 3 is placed in front of the control box 2. A lifting support arm 5 is vertically slidably installed on the top of the column 3. A lifting mechanism is provided inside the column 3, and the lifting mechanism is used to control the height of the lifting support arm 5. The lifting support arm 5 extends forward. An extended support plate 4 is provided on the front surface of the column 3, a reaction container 7 is fixed at the front end of the extended support plate 4, a drive motor 6 is installed at the front end of the lifting support arm 5, the drive motor 6 is placed directly above the reaction container 7, a stirring paddle is installed at the output end of the drive motor 6, the drive motor 6 and the stirring shaft are connected by a magnetic coupler to realize transmission, and the stirring paddle is placed inside the reaction container 7, a groove 702 is provided at the lower side of the reaction container 7, four docking joints 703 are evenly arranged inside the groove 702, and the four docking joints 703 correspond to a sampling tube and three sensors respectively. The three sensors are a pH sensor, a temperature sensor, and a Do sensor, and all transmit data to the control box 2 through cables.

[0023] Please refer to Figure 2 and Figure 3As shown, a plurality of through holes 301 are evenly opened on the front surface of the column 3, and the sensor cable sampling hoses pass through the through holes 301 one by one. A squeezing bolt 9 is evenly and slidably installed on one side of the column 3, and the squeezing bolt 9 corresponds to the through hole 301 one by one. The end of the squeezing bolt 9 is provided with an arc surface 901, and the arc surface 901 is placed on the inner side of the column 3 to squeeze and fix the cable passing through the through hole 301, and to organize and guide the cable to prevent tangling and confusion. The through hole 301 supports the center of the suspended cable, which can reduce the installation force of the cable end and prevent it from falling off.

[0024] Please refer to Figure 3 As shown, an elastic sheet 10 is provided on one side of the column 3, and a locking bolt 11 is passed through the rear end of the elastic sheet 10. The locking bolt 11 is screwed on the column 3, and the elastic sheet 10 extends beyond the front surface of the column 3. The elastic sheet 10 is fixed by the locking bolt 11 and keeps it in a horizontal state and close to one side of the column 3. A track groove 101 is provided on the surface of the elastic sheet 10, and the extrusion bolt 9 passes through the track groove 101. A concave ring 902 is provided on the end of the surface of the extrusion bolt 9 away from the through hole 301, and the concave ring 902 is adapted to the track groove 101. When the end of the elastic sheet 10 is deformed outward, the extrusion bolt 9 can be pulled to move outward to keep the corresponding through hole 301 unobstructed, thereby facilitating the installation of the cable.

[0025] Please refer to Figure 2 As shown, the front surface of the column 3 is provided with a boss 302, and the inner side of the boss 302 is screwed with a screw 12 through the horizontal screw thread. The screw 12 is placed between two adjacent through holes 301. There are four through holes 301, and the screw 12 is placed in the center position, so that the connection position of the screw 12 and the push rod 13 is placed in the center.

[0026] Among them, a knob 121 is provided at one end of the screw 12, and a push rod 13 is installed at the other end of the screw 12 through a bearing. The push rod 13 is vertically arranged and vertically spans the inner side of multiple elastic sheets 10. The push rod 13 corresponds to the protruding part of the elastic sheet 10, so that during installation or debugging, the push rod 13 can be moved outward to squeeze the multiple elastic sheets 10, so that the multiple elastic sheets 10 are deformed outward at the same time.

[0027] Please refer to Figure 1 As shown, a floor drain pipe 8 is symmetrically connected to the bottom of the reaction container 7, and observation windows 701 are symmetrically opened on the surface of the reaction container 7 to facilitate observation of the interior.

[0028] Working principle: When in use, first keep the reaction container 7 sealed, then control the height of the drive motor 6 by lifting the support arm 5, and then control the position of the stirring paddle at the output end of the drive motor 6 for easy installation. The four docking joints 703 are respectively installed with sampling hoses and sensors, and the cables of the hoses and sensors will pass through the through-hole 301 and be connected to the control box 2. Due to the elastic force of the elastic sheet 10, the elastic sheet 10 is always attached to the side of the column 3, and then the extrusion bolt 9 is pushed to the innermost side through the cooperation of the track groove 101 and the concave ring 902. At this time, the arc surface 901 can squeeze and fix the cable passing through the through-hole 301. When multiple cables need to be adjusted during installation or debugging, the axial position of the screw 12 can be controlled by rotating the knob 121, and then the position of the push rod 13 can be controlled. The push rod 13 can push multiple elastic sheets 10 at the same time, so that the multiple extrusion bolts 9 move outward synchronously, so that the inside of the through-hole 301 remains unobstructed.

[0029] The above description is merely a preferred embodiment of the present invention; however, the scope of protection of the present invention is not limited thereto. Any person skilled in the art who, within the technical scope disclosed in the present invention, makes equivalent substitutions or modifications based on the technical solutions and improved concepts of the present invention shall be covered by the scope of protection of the present invention.

Claims

1. A magnetic stirring device for a bioreactor, comprising a movable plate (1), wherein universal wheels are provided at the bottom angles of the movable plate (1), and characterized in that: A control box (2) is provided on the rear side of the upper surface of the movable plate (1), and a control panel (201) is provided on one side of the top of the control box (2). A column (3) is vertically fixed on the upper surface of the movable plate (1), and a lifting support arm (5) is vertically slidably installed on the top of the column (3). The lifting support arm (5) extends forward, and an extension support plate (4) is provided on the front side surface of the column (3). A reaction container (7) is fixed at the front end of the extension support plate (4). A driving motor (6) is installed at the front end of the lifting support arm (5), and the driving motor (6) is placed just above the reaction container (7). The output end of the driving motor (6) is provided with a stirring paddle, and the stirring paddle is placed inside the reaction container (7). A groove (702) is provided below one side of the reaction container (7), and four docking joints (703) are evenly provided inside the groove (702). A plurality of through holes (301) are evenly provided on the front surface of the column (3). An extrusion bolt (9) is evenly slidably installed on one side of the column (3), and the extrusion bolt (9) corresponds to the through hole (301) one by one. An arc surface (901) is provided at the end of the extrusion bolt (9), and the arc surface (901) is placed inside the column (3).

2. The magnetic stirring device for a bioreactor according to claim 1, characterized in that: An elastic sheet (10) is provided on one side of the column (3), a locking bolt (11) passes through the rear end of the elastic sheet (10), the locking bolt (11) is screwed onto the column (3), and the elastic sheet (10) extends beyond the front surface of the column (3).

3. The magnetic stirring device for a bioreactor according to claim 2, characterized in that: A track groove (101) is provided on the surface of the elastic sheet (10), the extrusion bolt (9) passes through the track groove (101), and a concave ring (902) is provided on the end of the surface of the extrusion bolt (9) away from the through hole (301), and the concave ring (902) is adapted to the track groove (101).

4. The magnetic stirring device for a bioreactor according to claim 3, characterized in that: A boss (302) is provided on the front surface of the column (3), and a screw rod (12) is passed through the inner side of the boss (302) through a horizontal screw thread, and the screw rod (12) is placed between two adjacent through holes (301).

5. The magnetic stirring device for a bioreactor according to claim 4, characterized in that: A knob (121) is provided at one end of the screw rod (12), and a push rod (13) is installed at the other end of the screw rod (12) through a bearing. The push rod (13) is vertically arranged and vertically spans the inner sides of multiple elastic sheets (10), and the push rod (13) corresponds to the protruding portion of the elastic sheet (10).

6. The magnetic stirring device for a bioreactor according to claim 1, characterized in that: The bottom of the reaction container (7) is symmetrically connected to a floor drain pipe (8), and the surface of the reaction container (7) is symmetrically provided with an observation window (701).

7. The magnetic stirring device for a bioreactor according to claim 1, characterized in that: The four docking joints (703) correspond to one sampling tube and three sensors respectively.

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