High-speed mixing granulator for producing paracetamol and chlorphenamine maleate preparation

Abstract

The utility model discloses a high-speed mixing granulator for producing a paracetamol and chlorphenamine maleate preparation. The high-speed mixing granulator comprises a granulator body and a feed hopper arranged at the right side of the upper end of the granulator body, during use, an air cylinder is started firstly, the air cylinder works to enable a protective baffle to move downwards, so that a clamping groove is clamped into a clamping block, extrusion pads on the two sides of the clamping groove extrude the clamping block, then a powder material and an adhesive are added into a granulator body through a feeding hopper, and the powder material and the adhesive can be fully mixed in the granulator body through stirring; then the air cylinder is started again, the air cylinder works to pull the protective baffle upwards, at the moment, the high-speed air injection device is started, the high-speed air injection device works to blow strong airflow into the granulator body, and when the wet soft material passes through the through holes, small particles are formed; and through the arrangement of the air cylinder, the telescopic rod, the protective baffle, the clamping block, the clamping groove and the extrusion pad, the sealing performance of the granulator body is enhanced.

Description

Technical Field

[0001] The utility model belongs to the technical field related to pharmaceutical engineering, and particularly relates to a high-speed mixing granulator for the production of acetaminophen preparations. Background Art

[0002] Paracetamol and xanthine preparation is a commonly used over-the-counter drug, mainly used to relieve symptoms caused by colds, such as headache, fever, nasal congestion and cough. In the process of producing this preparation, a high-speed mixing granulator plays a key role. This equipment can convert raw drug powder and excipients into granules with a certain hardness and strength through a wet granulation process to facilitate subsequent tableting or filling into capsules. The existing high-speed mixing granulator for the production of paracetamol and xanthine preparation is mainly composed of a feed hopper, a through chute, a motor body, a through net, a granulator body, a support column, a support pad, a reinforcing plate, a rotating shaft, a connector, a nozzle, a connecting ring, a stirring rod and other components. The existing high-speed mixing granulator for the production of paracetamol and xanthine preparation will affect the normal use of the equipment if leakage occurs when the powder material and the adhesive are stirred. Therefore, a high-speed mixing granulator for the production of paracetamol and xanthine preparation is indispensable. Utility Model Content

[0003] The purpose of the utility model is to provide a high-speed mixing granulator for the production of acetaminophen and xanthine preparations, so as to solve the problem in the above background technology that leakage of powder materials and adhesives during stirring in the existing high-speed mixing granulator for the production of acetaminophen and xanthine preparations may affect the normal use of the equipment.

[0004] To achieve the above object, the present invention provides the following technical solution: a high-speed mixing granulator for the production of paracetamol and chlorpheniramine preparations, comprising

[0005] A granulator body and a feed hopper arranged at the right side of the upper end of the granulator body;

[0006] A motor body is installed at the upper end of the granulator body and at the left side of the feed hopper, and a rotating shaft is connected to the interior of the granulator body and at the lower end of the motor body;

[0007] A connecting ring is installed at an external position of the rotating shaft, and stirring rods are connected to the inside of the granulator body and at positions on the left and right sides of the connecting ring;

[0008] A through slot is provided at a lower left side of the granulator body, and a through net is installed at an inner position of the through slot;

[0009] A nozzle is provided at the lower right side of the granulator body, a connector is installed at the outer position of the nozzle, and a connecting pipe is connected to the right side of the connector.

[0010] The motor body is electrically connected to an external power source, and the connecting pipe is connected to an external high-speed jet device;

[0011] A protective shell is installed at the upper end of the granulator body and at the left side of the motor body, the upper end of the protective shell is connected with an air pipe, a cylinder is installed at the internal position of the protective shell, a telescopic rod is provided at the lower end of the cylinder, a protective baffle is connected at the lower end of the telescopic rod and at the internal position of the granulator body, a card slot is provided at the internal position of the lower end of the protective baffle, and extrusion pads are provided on the left and right sides of the card slot, a card block is installed at the internal bottom end of the granulator body and at the inner position of the card slot, the cylinder is connected to an external pneumatic device through an air pipe, and the sealing of the granulator body is enhanced by the arrangement of the cylinder, telescopic rod, protective baffle, card block, card slot and extrusion pad.

[0012] Preferably, a plurality of circular through holes are provided at the inner position of the through net, the plurality of circular through holes pass through the through net, and the diameters of the plurality of circular through holes are consistent.

[0013] Preferably, the card block is a solid rectangular parallelepiped structure, the card slot is a hollow rectangular parallelepiped structure, and the card slot and the card block are connected by plugging.

[0014] Preferably, the card slot and the extrusion pad are connected by gluing, and the extrusion pad is made of rubber material.

[0015] Preferably, a socket is provided inside the upper end of the granulator body and at an outer position of the telescopic rod, the rotating shaft and the feed hopper, and a mounting plate is connected to the upper end of the granulator body and at an outer position of the protective shell, the lower end of the motor body and the feed hopper.

[0016] Preferably, a mounting hole is provided at an internal position of the mounting plate, a fastening nut is installed inside the mounting hole and at the upper end of the mounting plate, and the mounting plate is fixedly connected to the pelletizer body by the fastening nut, so that the protective shell, the motor body and the feed hopper are installed at the upper end of the pelletizer body.

[0017] Preferably, support columns are welded at the four corners of the lower end of the granulator body, support pads are installed at the lower ends of the support columns, and reinforcing plates are welded at the inner sides of the support columns.

[0018] Preferably, the granulator body, support column and extrusion plate are all made of stainless steel, and the support pad is made of rubber. The arrangement of the support column, support pad and reinforcement plate enhances the stability of the granulator body.

[0019] Compared with the prior art, the present invention provides a high-speed mixing granulator for the production of paracetamol and chlorpheniramine preparations, which has the following beneficial effects:

[0020] The utility model improves a high-speed mixing granulator for the production of acetaminophen and pheniramine preparations. When the high-speed mixing granulator for the production of acetaminophen and pheniramine preparations is used, first the motor body is connected to the external power supply, the cylinder is connected to the external pneumatic device through the air pipe, the connecting pipe is connected to the external high-speed jet device, and then the cylinder is started. The operation of the cylinder will cause the protective baffle to move downward, so that the inner groove of the lower end of the protective baffle is stuck in the inside of the blocking block. When the blocking block is stuck in the inside of the groove, the extrusion pads on the left and right sides of the groove will squeeze the blocking block, so that the protective baffle will cover the through groove, and then the powder material and the adhesive are added to the inside of the granulator body through the feed hopper, and then the motor body is started and the electric The operation of the machine body will drive the rotating shaft to rotate and thus drive the stirring rod to rotate. The powder material and the adhesive will be fully mixed inside the granulator body through the stirring rod to form a moist soft material. Then the motor is turned off and the cylinder is started again. The operation of the cylinder will pull the protective baffle upwards. At this time, the high-speed jet device is started. The operation of the high-speed jet device will blow a strong airflow into the granulator body through the connecting pipe and the nozzle, so that the moist soft material collides with the through-net. When the moist soft material passes through the through-hole, small particles are formed. The setting of the cylinder, telescopic rod, protective baffle, card block, card slot and extrusion pad strengthens the sealing of the granulator body to avoid leakage of powder material and adhesive during stirring, which affects the normal use of the equipment. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 The utility model is a schematic diagram of the overall structure of a high-speed mixing granulator for the production of acetaminophen and xanthine preparations.

[0022] Figure 2 This is a structural schematic diagram of the protective baffle of the high-speed mixing granulator used in the production of acetaminophen and xanthine preparations of the utility model moving up.

[0023] Figure 3 The utility model is a schematic diagram of the structure of the high-speed mixing granulator for the production of acetaminophen and chlorpheniramine preparations with enlarged blocks and slots.

[0024] In the figure: 1. feed hopper; 2. through slot; 3. motor body; 4. air pipe; 5. protective shell; 6. cylinder; 7. telescopic rod; 8. protective baffle; 9. through net; 10. granulator body; 11. support column; 12. support pad; 13. reinforcement plate; 14. rotating shaft; 15. connector; 16. connecting pipe; 17. nozzle; 18. connecting ring; 19. stirring rod; 20. slot; 21. block; 22. extrusion pad. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0026] The utility model provides Figure 1-3 The high-speed mixing granulator for the production of acetaminophen and pheniramine preparations shown in the figure comprises a granulator body 10 and a feed hopper 1 arranged at the upper right side of the granulator body 10; a motor body 3 is installed at the upper end of the granulator body 10 and at the left side of the feed hopper 1, and a rotating shaft 14 is connected to the interior of the granulator body 10 and at the lower end of the motor body 3; a connecting ring 18 is installed at the outer position of the rotating shaft 14, and a stirring rod 19 is connected to the interior of the granulator body 10 and at the left and right sides of the connecting ring 18; a through groove 2 is provided at the lower left side of the granulator body 10, and a through net 9 is installed at the inner position of the through groove 2; a nozzle 17 is provided at the lower right side of the granulator body 10, a connector 15 is installed at the outer position of the nozzle 17, and a connecting pipe 1 is connected to the right side of the connector 15. 6, the motor body 3 is electrically connected to the external power supply, and the connecting pipe 16 is connected to the external high-speed jet device; a protective shell 5 is installed at the upper end of the granulator body 10 and at the left side of the motor body 3, and the upper end of the protective shell 5 is connected with the air pipe 4, and a cylinder 6 is installed at the inner position of the protective shell 5, and a telescopic rod 7 is provided at the lower end of the cylinder 6. The lower end of the telescopic rod 7 is connected with a protective baffle 8 at the inner position of the granulator body 10, and a slot 20 is provided at the lower end of the protective baffle 8. The left and right sides of the slot 20 are provided with an extrusion pad 22. The inner bottom end of the granulator body 10 and the inner side of the slot 20 are provided with a block 21. The cylinder 6 is connected to the external pneumatic device through the air pipe 4. The sealing of the granulator body 10 is strengthened by the arrangement of the cylinder 6, the telescopic rod 7, the protective baffle 8, the block 21, the slot 20 and the extrusion pad 22.

[0027] like Figure 1 、 Figure 2 and Figure 3As shown, in order to enhance the sealing performance of the granulator body 10, when using the high-speed mixing granulator for the production of acetaminophen and phenanthroline preparations, first connect the motor body 3 to the external power supply, connect the cylinder 6 to the external pneumatic device through the air pipe 4, connect the connecting pipe 16 to the external high-speed jet device, and then start the cylinder 6. The operation of the cylinder 6 will cause the protective baffle 8 to move downward, so that the internal groove 20 at the lower end of the protective baffle 8 is stuck in the inside of the block 21. When the block 21 is stuck in the inside of the groove 20, the extrusion pads 22 on the left and right sides of the groove 20 will squeeze the block 21, so that the protective baffle 8 will cover the through groove 2, and then the powder material and the adhesive are added to the interior of the granulator body 10 through the feed hopper 1, and then start the motor body 3. The operation of the motor body 3 will bring The rotating shaft 14 rotates to drive the stirring rod 19 to rotate. The powder material and the adhesive are fully mixed inside the granulator body 10 by the stirring of the stirring rod 19 to form a moist soft material. Then the motor body 3 is turned off and the cylinder 6 is started again. The cylinder 6 will pull the protective baffle 8 upward when it works. At this time, the high-speed jet device is started. The high-speed jet device will blow a strong airflow into the granulator body 10 through the connecting pipe 16 and the nozzle 17, so that the moist soft material collides with the through net 9. When the moist soft material passes through the through hole, small particles are formed. The arrangement of the cylinder 6, the telescopic rod 7, the protective baffle 8, the card block 21, the card slot 20 and the extrusion pad 22 strengthens the sealing of the granulator body 10 to prevent the powder material and the adhesive from leaking during stirring and affecting the normal use of the equipment.

[0028] A plurality of circular through holes are provided at the internal position of the through net 9, and the plurality of circular through holes pass through the through net 9. The diameters of the plurality of circular through holes are consistent. The card block 21 is a solid rectangular structure, and the card slot 20 is a hollow rectangular structure. The card slot 20 is connected to the card block 21 by plugging, and the card slot 20 is connected to the extrusion pad 22 by gluing. The extrusion pad 22 is made of rubber material.

[0029] like Figure 1 、 Figure 2 and Figure 3 As shown, in order to enhance the stability and sealing of the docking between the block 21 and the slot 10, when using the high-speed mixing granulator for the production of acetaminophen and xanthine preparations, the cylinder 6 is started first. The operation of the cylinder 6 will cause the protective baffle 8 to move downward, so that the slot 20 inside the lower end of the protective baffle 8 is stuck into the block 21. When the block 21 is stuck into the slot 20, the squeezing pads 22 on the left and right sides of the slot 20 will squeeze the block 21. By setting the squeezing pads 22, the stability and sealing of the docking between the block 21 and the slot 10 are enhanced.

[0030] A jack is provided inside the upper end of the granulator body 10 and at the outer side of the telescopic rod 7, the rotating shaft 14 and the feed hopper 1. A mounting plate is connected to the upper end of the granulator body 10 and at the lower end of the protective shell 5, the motor body 3 and the outer side of the feed hopper 1. A mounting hole is provided at the inner position of the mounting plate, and a fastening nut is installed inside the mounting hole and at the upper end position of the mounting plate. The mounting plate and the granulator body 10 are fixedly connected by the fastening nut, so that the protective shell 5, the motor body 3 and the feed hopper 1 are installed at the upper end of the granulator body 10.

[0031] like Figure 1 and Figure 2 As shown, in order to facilitate the installation and disassembly of the protective shell 5, the motor body 3 and the feed hopper 1, when using the high-speed mixing granulator for the production of acetaminophen preparations, first insert the telescopic rod 7, the rotating shaft 14 and the feed hopper 1 into the jack, so that the protective shell 5, the motor body 3 and the feed hopper 1 are placed on the upper end of the granulator body 10 through the mounting plate, and then the mounting plate is mounted on the upper end of the granulator body 10 through the fastening nut, so that the protective shell 5, the motor body 3 and the feed hopper 1 are fixed to the upper end of the granulator body 10. The arrangement of the mounting plate and the fastening nut facilitates the installation and disassembly of the protective shell 5, the motor body 3 and the feed hopper 1.

[0032] Support columns 11 are welded at the four corners of the lower end of the granulator body 10, a support pad 12 is installed at the lower end of the support column 11, and a reinforcement plate 13 is welded at the inner side of the support column 11. The granulator body 10, support columns 11 and extrusion plate are all made of stainless steel, and the support pad 12 is made of rubber material. The arrangement of the support columns 11, support pad 12 and reinforcement plate 13 enhances the stability of the granulator body 10.

[0033] like Figure 1 and Figure 2 As shown, in order to enhance the stability of the placement of the granulator body 10, when using the high-speed mixing granulator for the production of acetaminophen and pheniramine preparations, the support pad 12 is first sleeved on the lower end of the support column 11, and then the support column 11 is welded to the four corner positions of the lower end of the granulator body 10, and then the reinforcing plate 13 is welded at the inner position of the support column 10, and then the granulator body 10 is contacted with the ground through the support pad 12, so that the granulator body 10 is placed on the ground through the support column 11. Through the arrangement of the support column 11, the support pad 12 and the reinforcing plate 13, the stability of the placement of the granulator body 10 is enhanced, so that the high-speed mixing granulator for the production of acetaminophen and pheniramine preparations can be better used.

[0034] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A high-speed mixing granulator for the production of paracetamol and chlorpheniramine preparations, comprising A granulator body (10) and a feed hopper (1) arranged at a position slightly to the right of the upper end of the granulator body (10); A motor body (3) is installed at the upper end of the pelletizer body (10) and at the left side of the feed hopper (1), and a rotating shaft (14) is connected to the interior of the pelletizer body (10) and at the lower end of the motor body (3); A connecting ring (18) is installed at an external position of the rotating shaft (14), and stirring rods (19) are connected to the inside of the granulator body (10) and at positions on the left and right sides of the connecting ring (18); A through slot (2) is provided at a lower left side of the granulator body (10), and a through net (9) is installed at an inner position of the through slot (2); A nozzle (17) is provided at the lower right side of the granulator body (10), a connector (15) is installed at the outer position of the nozzle (17), and a connecting pipe (16) is connected to the right side of the connector (15). The motor body (3) is electrically connected to an external power source, and the connecting pipe (16) is connected to an external high-speed jet device; Its characteristics are: A protective housing (5) is installed at the upper end of the pelletizer body (10) and at the left side of the motor body (3); an air pipe (4) is connected to the upper end of the protective housing (5); a cylinder (6) is installed at the inner position of the protective housing (5); a telescopic rod (7) is provided at the lower end of the cylinder (6); a protective baffle (8) is connected to the lower end of the telescopic rod (7) and at the inner position of the pelletizer body (10); a protective baffle (8) is provided at the inner position of the lower end of the protective baffle (8). A card slot (20) is provided, and compression pads (22) are provided at the left and right sides of the card slot (20). A card block (21) is installed at the inner bottom of the granulator body (10) and located inside the card slot (20). The cylinder (6) is connected to an external pneumatic device through an air pipe (4). The arrangement of the cylinder (6), telescopic rod (7), protective baffle (8), card block (21), card slot (20) and compression pad (22) strengthens the sealing performance of the granulator body (10).

2. A high-speed mixing granulator for the production of paracetamol and chlorpheniramine preparations according to claim 1, characterized in that: A plurality of circular through holes are provided at the inner position of the through net (9), the plurality of circular through holes pass through the through net (9), and the diameters of the plurality of circular through holes are consistent.

3. A high-speed mixing granulator for the production of paracetamol and chlorpheniramine preparations according to claim 1, characterized in that: The card block (21) is a solid rectangular parallelepiped structure, the card slot (20) is a hollow rectangular parallelepiped structure, and the card slot (20) and the card block (21) are connected by plugging.

4. A high-speed mixing granulator for the production of paracetamol and chlorpheniramine preparations according to claim 3, characterized in that: The clamping slot (20) and the extrusion pad (22) are connected by gluing, and the extrusion pad (22) is made of rubber material.

5. A high-speed mixing granulator for the production of paracetamol and chlorpheniramine preparations according to claim 1, characterized in that: A socket is provided inside the upper end of the pelletizer body (10) and located outside the telescopic rod (7), the rotating shaft (14) and the feed hopper (1); and a mounting plate is connected to the upper end of the pelletizer body (10) and located outside the protective housing (5), the lower end of the motor body (3) and the feed hopper (1).

6. A high-speed mixing granulator for the production of paracetamol and chlorpheniramine preparations according to claim 5, characterized in that: A mounting hole is provided at an inner position of the mounting plate, and a fastening nut is installed inside the mounting hole and at an upper end position of the mounting plate. The mounting plate and the pelletizer body (10) are fixedly connected via the fastening nut, so that the protective housing (5), the motor body (3) and the feed hopper (1) are mounted on the upper end of the pelletizer body (10).

7. A high-speed mixing granulator for the production of paracetamol and chlorpheniramine preparations according to claim 6, characterized in that: Support columns (11) are welded at the four corner positions of the lower end of the granulator body (10), a support pad (12) is installed at the lower end position of the support column (11), and a reinforcing plate (13) is welded at the inner side position of the support column (11).

8. A high-speed mixing granulator for the production of paracetamol and chlorpheniramine preparations according to claim 7, characterized in that: The granulator body (10), the support column (11) and the extrusion plate are all made of stainless steel, and the support pad (12) is made of rubber. The arrangement of the support column (11), the support pad (12) and the reinforcing plate (13) enhances the stability of the placement of the granulator body (10).

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