Reaction equipment

Abstract

The utility model provides reaction equipment, and relates to the technical field of reaction detection. The reaction equipment comprises a reaction assembly and a detection assembly, the reaction assembly comprises a reaction chamber, a gas inlet end and a gas outlet end; the reaction chamber is respectively connected with the gas inlet end and the gas outlet end; the reaction chamber is configured to provide a reaction place for physicochemical reaction; the gas inlet end and the gas outlet end are configured to provide a passage for gas flowing through the reaction chamber; the detection assembly comprises a first detection element, a second detection element and a third detection element; the first detection element is arranged at the air inlet end; the second detection element is arranged in the reaction chamber; the third detection element is arranged at the air outlet end; the first detection element, the second detection element, and the third detection element are configured to monitor material characteristics at their locations. The reaction equipment provided by the utility model can monitor the material characteristics inside and at the two ends of the reaction chamber in real time, and data provided by the reaction equipment can be used for adjusting reaction parameters in real time or used for subsequent data analysis and optimization.

Description

Technical Field

[0001] The present application provides a reaction device, which relates to the technical field of reaction detection. Background Art

[0002] Existing reaction equipment is typically equipped with only basic detection components, which can only monitor the properties of specific substances and fail to comprehensively monitor other key parameters in the reaction process. This incomplete parameter collection directly leads to an inability to accurately analyze and judge the physical and chemical reactions taking place. Furthermore, it may be impossible to fully and comprehensively capture changes during the reaction, resulting in an inability to respond and adjust reaction conditions in a timely manner, which can also affect reaction control accuracy and product quality.

[0003] Because the metabolism of plant and animal cells and microorganisms has two pathways, one is a healthy state with complete oxygen consumption, and the other is an unhealthy state with incomplete oxygen consumption. In the unhealthy state, the oxygen consumed and the carbon dioxide released are not one-to-one corresponding, resulting in the inability of existing bioreactors to accurately judge the need for feed based solely on oxygen changes. In order to control the stability of pH, real-time changing carbon dioxide needs to be introduced. As a result, the carbon dioxide concentration in the direct detection system cannot truly reflect the amount of carbon dioxide produced by the metabolism of plant and animal cells and microorganisms. This inaccuracy affects the control of the environment within the bioreactor, and thus affects the efficiency of the biological process and the quality of the product. Utility Model Content

[0004] In view of this, the purpose of the embodiments of the present application is to provide a reaction device to improve the problems of incomplete monitoring and inaccurate metabolic status judgment in existing bioreactor technology, while improving the control accuracy and culture efficiency of the biological reaction process.

[0005] An embodiment of the present application provides a reaction device, which includes: a reaction component and a detection component; the reaction component includes: a reaction chamber, an air inlet end and an air outlet end; the reaction chamber is connected to the air inlet end and the air outlet end respectively; the reaction chamber is configured to provide a reaction site for physical and chemical reactions; the air inlet end and the air outlet end are configured to provide a path for the gas flowing through the reaction chamber; the detection component includes: a first detection element, a second detection element and a third detection element; the first detection element is arranged at the air inlet end; the second detection element is arranged inside the reaction chamber; the third detection element is arranged at the air outlet end; the first detection element, the second detection element and the third detection element are configured to monitor the material properties at their locations.

[0006] In this implementation, the first detection element measures the properties of the substance at the inlet; the second detection element measures the properties of the substance within the reaction chamber; and the third detection element measures the properties of the substance at the outlet. Corresponding data is collected for each step of the reaction, including the initial phase, the reaction phase, and the final phase. This provides the prerequisite for accurate analysis and judgment of the physical and chemical reactions occurring within the reaction equipment. This comprehensive and continuous detection method allows the reaction equipment to accurately reflect the status of the ongoing physical and chemical reactions.

[0007] Optionally, the reaction equipment further includes: an air intake assembly; the air intake assembly is connected to the air intake end of the reaction assembly, and includes: a first pipeline and a flow controller; the first pipeline is configured to introduce gas into the reaction assembly; the flow controller is arranged at the end of the first pipeline close to the reaction assembly; the flow controller is configured to control the gas flow rate in the first pipeline; wherein, the gas includes a single gas and / or a mixed gas.

[0008] In the above implementation, gas enters through the first pipeline, and a flow controller is provided to control the gas flow in the first pipeline, thereby achieving control over the reactant (here, gas) at the inlet end. This not only ensures a stable supply of reactants but also helps maintain the pressure and temperature within the reaction system. Furthermore, the flow controller maintains a defined flow ratio to ensure smooth reaction progress. Flow control also allows for adjustments to the reaction process based on real-time data.

[0009] Optionally, the air inlet component also includes: a second pipe; the end of the second pipe close to the reaction component is connected to the air inlet end of the reaction device; the second pipe is used to input the gas into the reaction component; the first pipe is connected to the side wall of the second pipe along the tangential direction of the second pipe.

[0010] In the above implementation process, when the first pipe is connected to the side wall of the second pipe along the tangential direction of the second pipe, the gas entering the second pipe will be in the tangential direction, which helps to break the static gas layer in the second pipe, form a rotating airflow in the second pipe to promote the uniform distribution of the gas, so that the contact between the gas is more sufficient and the mixing efficiency is improved.

[0011] Optionally, the first detection element is connected to the inside of the second pipe; the first detection element includes: a first oxygen sensor and a first carbon dioxide sensor; the first oxygen sensor is configured to detect the oxygen content in the gas passed into the air intake end; the first carbon dioxide sensor is configured to detect the carbon dioxide content in the gas passed into the air intake end.

[0012] In the above implementation, the first oxygen sensor detects the oxygen content of the gas introduced into the inlet, and the first carbon dioxide sensor detects the carbon dioxide content of the gas introduced into the inlet. By monitoring the oxygen and carbon dioxide content at the inlet in real time, the gas composition during the reaction can be controlled, thereby providing a suitable environment for the reaction. Furthermore, gas monitoring helps optimize reaction conditions. For example, by adjusting the ratio of oxygen to carbon dioxide, a specific chemical reaction or biological process can be promoted.

[0013] Optionally, the second detection element includes: at least one of: a weight sensor, a temperature sensor, a pH sensor, and a second oxygen sensor; wherein the weight sensor is configured to detect the weight of the reactant undergoing a physical and chemical reaction inside the reaction chamber; the temperature sensor is configured to detect the temperature of the reactant undergoing a physical and chemical reaction inside the reaction chamber; the pH sensor is configured to detect the pH value of the reactant undergoing a physical and chemical reaction inside the reaction chamber; and the second oxygen sensor is configured to detect the dissolved oxygen content of the reactant undergoing a physical and chemical reaction inside the reaction chamber.

[0014] In the above implementation process, the weight sensor detects the weight of the reactants undergoing physical and chemical reactions inside the reaction chamber. By monitoring the weight changes of the reactants, the feeding strategy can be adjusted in time to ensure the continuity and uniformity of the reaction. The temperature sensor detects the temperature of the reactants undergoing physical and chemical reactions inside the reaction chamber. Temperature is a key factor affecting the chemical reaction rate and product quality. Temperature control helps to optimize reaction conditions and improve reaction efficiency and selectivity. The pH sensor detects the pH value of the reactants undergoing physical and chemical reactions inside the reaction chamber. Changes in pH directly affect the activity and reaction path of the reactants. By real-time monitoring and controlling the pH value, the optimal biochemical environment can be maintained, especially in biological fermentation and acid-base sensitive reaction processes. The second oxygen sensor detects the dissolved oxygen content of the reactants undergoing physical and chemical reactions inside the reaction chamber. Dissolved oxygen is a key indicator for measuring the self-purification capacity of water bodies and the health of the ecological environment. In the biological reaction process, the control of dissolved oxygen is crucial for cell growth and metabolic activity. Through this diversified monitoring configuration, the reaction equipment provided in the embodiment of the present application can fully grasp the physical and chemical state inside the reaction chamber, providing strong data support for controlling reaction conditions.

[0015] Optionally, the reaction equipment further includes: a third pipe and a heater; the third pipe is connected to the gas outlet end of the reaction component; the third pipe is configured to transmit the processed gas to an external device; the heater is arranged near the third pipe; the heater is configured to heat the third pipe based on heat transfer.

[0016] In this implementation, the third pipe is directly connected to the gas outlet of the reaction assembly, transmitting the gas processed within the reaction chamber to external equipment. A heater heats the gas within the third pipe, accelerating the evaporation of moisture from the gas, ensuring that the discharged gas meets dryness requirements. By heating the evaporated moisture, condensation can prevent clogging or corrosion of the pipe's inner wall, extending its service life and reducing maintenance costs.

[0017] Optionally, the third detection element is arranged inside the third pipe; the third detection element includes: a third oxygen sensor and a third carbon dioxide sensor; the third detection element is configured to detect the content of each gas component in the gas passed into the gas outlet; wherein the content of each gas component includes oxygen content and carbon dioxide content; the third oxygen sensor is configured to detect the oxygen content in the gas passed into the gas outlet; the third carbon dioxide sensor is configured to detect the carbon dioxide content in the gas passed into the gas outlet.

[0018] In the above implementation, a third oxygen sensor detects the oxygen content in the gas introduced into the outlet, and a third carbon dioxide sensor detects the carbon dioxide content in the gas introduced into the outlet. Real-time monitoring of gas composition at the outlet, such as oxygen and carbon dioxide content, provides direct feedback on the reaction progress, facilitating timely adjustment of reaction conditions, such as temperature, pH, and stirring speed, to optimize reaction rate and product quality. Monitoring the oxygen and carbon dioxide content in the outlet gas can help assess the operating status of the bioreactor, and the collected outlet gas composition data can be used for subsequent data analysis to improve the bioreactor process.

[0019] Optionally, the reaction device further comprises: a feeding component; the feeding component is used to compensate the reaction chamber based on substances detected by the first detection element, the second detection element and the third detection element.

[0020] In this implementation, the feeding component dynamically adjusts the type and amount of feed based on data provided by the detection element to optimize the bioreaction process. Through precise control of the feeding component, the nutritional needs of microbial growth can be met, promoting rapid cell proliferation and efficient product synthesis, thereby improving the efficiency of the bioreaction and product quality.

[0021] Optionally, the feeding assembly includes: a feeding container and a feeding controller; the feeding container is connected to the reaction chamber, and the feeding container is configured to place reactants related to the physicochemical reaction in the reaction chamber; wherein the reactants include biological culture medium for the relevant physicochemical reaction; the feeding controller is configured to adjust the rate at which the reactants in the feeding container are transported to the reaction chamber.

[0022] In this implementation, the feed controller automatically adjusts the rate at which reactants are delivered from the feed container to the reaction chamber based on detected material properties, such as oxygen and carbon dioxide levels. This not only improves the accuracy of bioreaction monitoring but also enhances the ability to control reaction conditions. This improves the quality and safety of gas processing and the adaptability of the equipment, providing more reliable and flexible operating conditions for a variety of complex bioreactions.

[0023] Optionally, the reaction component further includes: a stirrer; the stirrer extends into the interior of the reaction chamber; the stirrer is configured to stir the substance in the reaction chamber through its stirring end.

[0024] In the above implementation, the agitator's stirring action ensures uniform mixing of the contents within the reaction chamber, ensuring adequate contact between nutrients, gases, and microorganisms. By increasing the turbulence of the liquid, the agitator improves the efficiency of gas exchange and material transfer, particularly the transfer of dissolved oxygen and carbon dioxide, which helps meet the needs of cell growth and metabolic activity. In some biological reactions, reactants may precipitate or agglomerate. The agitation of the agitator prevents this phenomenon. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following is a brief introduction to the drawings required for use in the embodiments of the present application. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without creative work.

[0026] Figure 1 A simple schematic diagram of the reaction equipment provided in the embodiment of the present application;

[0027] Figure 2 Schematic diagram of the reaction equipment provided in the embodiment of the present application;

[0028] Figure 3 A schematic diagram of a tangential air intake cross section provided in an embodiment of the present application.

[0029] Icons: 100-reaction chamber; 110-air inlet end; 120-air outlet end; 130-first pipeline; 140-flow controller; 150-second pipeline; 160-third pipeline; 170-feeding assembly; 171-feeding container; 172-feeding controller; 180-agitator; 210-first detection element; 211-first oxygen sensor; 212-first carbon dioxide sensor; 220-second detection element; 221-weight sensor; 222-temperature sensor; 223-pH sensor; 224-second oxygen sensor; 230-third detection element; 231-third oxygen sensor; 232-third carbon dioxide sensor. DETAILED DESCRIPTION

[0030] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the embodiments described are only part of the embodiments of the present application, not all of them. Based on the embodiments of the present application, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the embodiments of the present application.

[0031] This application embodiment provides a reaction device, see Figure 1 , Figure 1 This is a simple schematic diagram of the reaction equipment provided in the embodiments of the present application.

[0032] The reaction equipment includes: a reaction component and a detection component; the reaction component includes: a reaction chamber 100, an air inlet end 110 and an air outlet end 120; the reaction chamber 100 is respectively connected to the air inlet end 110 and the air outlet end 120; the reaction chamber 100 is configured to provide a reaction site for physical and chemical reactions; the air inlet end 110 and the air outlet end 120 are configured to provide a path for the gas flowing through the reaction chamber 100; the detection component includes: a first detection element 210, a second detection element 220 and a third detection element 230; the first detection element 210 is arranged at the air inlet end 110; the second detection element 220 is arranged inside the reaction chamber 100; the third detection element 230 is arranged at the air outlet end 120; the first detection element 210, the second detection element 220 and the third detection element 230 are configured to monitor the material properties at their locations.

[0033] In the above implementation, the first detection element 210 detects the properties of the material at the air inlet 110; the second detection element 220 detects the properties of the material within the reaction chamber 100; and the third detection element 230 detects the properties of the material at the air outlet 120. Corresponding data is detected for each step of the reaction, including the initial phase, the reaction phase, and the final phase. This provides the prerequisite for accurate analysis and judgment of the physical and chemical reactions occurring within the reaction equipment. Through this comprehensive and continuous detection method, the reaction equipment can accurately reflect the status of the ongoing physical and chemical reactions.

[0034] Optionally, the detection element may be a weight sensor 221 , a temperature sensor 222 , a pH sensor 223 , an oxygen sensor, or a carbon dioxide sensor, and different elements may be configured for detection based on corresponding reaction measurement requirements.

[0035] For details, please see Figure 2 , Figure 2 Schematic diagram of the reaction equipment provided in the examples of the present application.

[0036] The reaction equipment also includes: an air intake assembly; the air intake assembly is connected to the air intake end 110 of the reaction assembly, and includes: a first pipe 130 and a flow controller 140; the first pipe 130 is configured to introduce gas into the reaction assembly; a flow controller 140 is set at the end of the first pipe 130 close to the reaction assembly; the flow controller 140 is configured to control the gas flow rate in the first pipe 130; wherein the gas includes a single gas and / or a mixed gas.

[0037] In the above implementation, gas enters through the first conduit 130, and a flow controller 140 is provided to control the gas flow rate in the first conduit 130, thereby controlling the reactant (here, gas) at the inlet end 110. This not only ensures a stable supply of reactants, but also helps maintain the pressure and temperature within the reaction system. Furthermore, the provision of the flow controller 140 maintains a defined flow ratio, allowing the reaction to proceed smoothly. The flow control also allows the reaction process to be adjusted based on real-time data.

[0038] Alternatively, the gas may be a single gas such as oxygen or carbon dioxide, or a mixed gas such as ammonia or air. In one embodiment, when the reactor is used for biological reactions, the effects of oxygen and carbon dioxide, or a mixture of the two gases, on the biological culture medium or plant and animal cells within the reaction chamber 100 must be considered.

[0039] The first detection element 210 is connected to the interior of the second pipe 150; the first detection element 210 includes: a first oxygen sensor 211 and a first carbon dioxide sensor 212; the first oxygen sensor 211 is configured to detect the oxygen content in the gas entering the air inlet end 110; the first carbon dioxide sensor 212 is configured to detect the carbon dioxide content in the gas entering the air inlet end 110.

[0040] In the above implementation, the first oxygen sensor 211 detects the oxygen content in the gas entering the air inlet 110, and the first carbon dioxide sensor 212 detects the carbon dioxide content in the gas entering the air inlet 110. By monitoring the oxygen and carbon dioxide content at the air inlet 110 in real time, the gas composition during the reaction can be controlled, thereby providing a suitable environment for the reaction. Furthermore, gas monitoring helps optimize reaction conditions. For example, by adjusting the ratio of oxygen to carbon dioxide, a specific chemical reaction or biological process can be promoted.

[0041] Optionally, the oxygen sensor may be a paramagnetic oxygen sensor, an electrochemical oxygen sensor, an optical oxygen sensor, a solid electrolyte oxygen sensor, etc.; the carbon dioxide sensor may be an infrared carbon dioxide sensor, an electrochemical carbon dioxide sensor, a capacitive carbon dioxide sensor, etc. In one embodiment, the high precision, fast response, and immunity to interference from other gases of the paramagnetic oxygen sensor are utilized to detect oxygen; while the simplicity, cost-effectiveness, and fast response of the non-dispersive infrared carbon dioxide sensor are utilized to measure carbon dioxide.

[0042] The second detection element 220 includes: at least one of: a weight sensor 221, a temperature sensor 222, a pH sensor 223, and a second oxygen sensor 224; wherein the weight sensor 221 is configured to detect the weight of the reactants undergoing the physical and chemical reaction within the reaction chamber 100; the temperature sensor 222 is configured to detect the temperature of the reactants undergoing the physical and chemical reaction within the reaction chamber 100; the pH sensor 223 is configured to detect the pH value of the reactants undergoing the physical and chemical reaction within the reaction chamber 100; and the second oxygen sensor 224 is configured to detect the dissolved oxygen content of the reactants undergoing the physical and chemical reaction within the reaction chamber 100.

[0043] In the above implementation process, the weight sensor 221 detects the weight of the reactants undergoing the physicochemical reaction inside the reaction chamber 100. By monitoring the weight changes of the reactants, the feeding strategy can be adjusted in time to ensure continuous reaction. The temperature sensor 222 detects the temperature of the reactants undergoing the physicochemical reaction inside the reaction chamber 100. Temperature is a key factor affecting the chemical reaction rate and product quality. Temperature control helps optimize reaction conditions and improve reaction efficiency and selectivity. The pH sensor 223 detects the pH value of the reactants undergoing the physicochemical reaction inside the reaction chamber 100. Changes in pH directly affect the activity of the reactants and the reaction path. By real-time monitoring and controlling the pH value, an optimal biochemical environment can be maintained, especially during biological fermentation and acid-base sensitive reactions. The second oxygen sensor 224 detects the dissolved oxygen content of the reactants undergoing the physicochemical reaction inside the reaction chamber 100. Dissolved oxygen is a key indicator for measuring the self-purification capacity of water bodies and the health of the ecological environment. In biological reaction processes, the control of dissolved oxygen is crucial for cell growth and metabolic activity. Through this diversified monitoring configuration, the reaction equipment provided by the embodiment of the present application can fully grasp the physicochemical state inside the reaction chamber 100, providing strong data support for controlling reaction conditions.

[0044] Optionally, you can choose: weight sensors based on load cells or piezoelectric sensors; thermocouples, thermistors, or fiber optic temperature sensors; glass electrodes or solid electrolyte pH sensors. Furthermore, all sensor components that come into contact with the reactants should be made of biocompatible materials to avoid adverse effects on the biological reaction process. The sensor should also be equipped with wireless data transmission capabilities to facilitate real-time monitoring and data recording while minimizing interference with the reaction chamber.

[0045] The reaction equipment also includes: a third pipe 160 and a heater (not shown); the third pipe 160 is connected to the gas outlet end 120 of the reaction component; the third pipe 160 is configured to transmit the treated gas to an external device; the heater (not shown) is arranged near the third pipe 160; the heater (not shown) is configured to heat the third pipe 160 based on heat transfer.

[0046] Optionally, a heater (not shown) is provided near the third pipe 160 and may be arranged around the pipe to provide uniform heat distribution; in cases where space is limited or specific heating requirements are required, the heater may only contact one side of the pipe; or the pipe may be provided with a PID-controlled electric heating function.

[0047] In the above implementation, third conduit 160 is directly connected to the gas outlet 120 of the reaction assembly, transmitting the gas processed within reaction chamber 100 to external equipment. A heater (not shown) heats the gas within third conduit 160, accelerating the evaporation of moisture from the gas, ensuring that the exhausted gas meets dryness requirements. By heating the evaporated moisture, clogging or corrosion of the conduit wall caused by condensation can be prevented, extending the conduit's service life and reducing maintenance costs.

[0048] The third detection element 230 is arranged inside the third pipeline 160; the third detection element 230 includes: a third oxygen sensor 231 and a third carbon dioxide sensor 232; the third detection element 230 is configured to detect the content of each gas component in the gas passed into the gas outlet 120; wherein the content of each gas component includes oxygen content and carbon dioxide content; the third oxygen sensor 231 is configured to detect the oxygen content in the gas passed into the gas outlet 120; the third carbon dioxide sensor 232 is configured to detect the carbon dioxide content in the gas passed into the gas outlet 120.

[0049] In the above implementation, third oxygen sensor 231 detects the oxygen content in the gas entering outlet 120, and third carbon dioxide sensor 232 detects the carbon dioxide content in the gas entering outlet 120. Real-time monitoring of gas composition at outlet 120, such as oxygen and carbon dioxide content, provides direct feedback on the reaction progress, facilitating timely adjustment of reaction conditions, such as temperature, pH, and stirring speed, to optimize reaction rate and product quality. Monitoring the oxygen and carbon dioxide content in the outlet gas helps assess the operating status of the bioreactor, and the collected outlet gas composition data can be used for subsequent data analysis to improve the bioreactor process.

[0050] Optionally, compensation is applied to the reaction chamber 100 based on the substances detected by the first detection element 210, the second detection element 220, and the third detection element 230. In calculating the specific amount of compensation or the compensation substance, existing calculation methods may be used or external computing equipment may be used.

[0051] In one embodiment, the difference between the inlet oxygen volume fraction A1 and the outlet oxygen volume fraction A2 can be calculated, while simultaneously communicating with the reactor controller to obtain the total inlet volume Q and the reactor culture medium volume V. The program collects data and performs calculations in real time, while also outputting the calculated result OUR in real time. The formula is: OUR = (A1 - A2) * Q / V.

[0052] The inlet carbon dioxide volume fraction B1 and the outlet carbon dioxide volume fraction B2 are differentially calculated, and the total inlet volume Q and the reactor culture medium volume V are obtained by communicating with the reaction equipment controller. Data is collected and calculated in real time within the program, and the calculation result CER is output in real time.

[0053] The formula is: CER = (B1-B2)*Q / V.

[0054] where A / B is the molar fraction (mmol / L), Q is the aeration rate (L / h), and V is the reactor volume (L). CER is the carbon dioxide evolution rate (mmol / L·h).

[0055] Based on the above calculations of online OUR and CER, the online respiratory quotient RQ can be calculated using the formula: RQ = CER / OUR.

[0056] where CER is the carbon dioxide evolution rate (mmol / L·H) and OUR is the oxygen consumption rate (mmol / L·H).

[0057] The reaction device further includes a feeding component 170 ; the feeding component 170 is used to provide compensation to the reaction chamber 100 based on substances detected by the first detection element 210 , the second detection element 220 , and the third detection element 230 .

[0058] In this implementation, feeding assembly 170 dynamically adjusts the type and amount of feed based on the data provided by the detection element and the compensation amount calculated based on this data to optimize the bioreaction process. Precise control by feeding assembly 170 can meet the nutritional needs of microbial growth, promote rapid cell proliferation and efficient product synthesis, and improve bioreaction efficiency and product quality.

[0059] The feeding assembly 170 includes: a feeding container 171 and a feeding controller 172; the feeding container 171 is connected to the reaction chamber 100, and the feeding container 171 is configured to place reactants related to the physical and chemical reactions in the reaction chamber; wherein the reactants include biological culture media for the relevant physical and chemical reactions; the feeding controller 172 is configured to adjust the rate at which the reactants in the feeding container 171 are transported to the reaction chamber.

[0060] In the above implementation, feeding controller 172 automatically adjusts the rate at which reactants in feeding container 171 are delivered to the reaction chamber based on detected material properties, such as oxygen and carbon dioxide content. This not only improves the accuracy of monitoring the bioreaction process but also enhances the ability to control reaction conditions, thereby improving the quality and safety of gas processing and the adaptability of the equipment, providing more reliable and flexible operating conditions for a variety of complex bioreactions.

[0061] In one embodiment, the online OUR obtained by the above calculation can be analyzed to set the OUR range {OUR1-OUR2} to correspond to the output feed rate range {BU1-BU2}.

[0062] When the online OUR changes within the range, the output BU of the feeding system also automatically changes within the corresponding range. The formula is: Output BU = (Online OUR - OUR1) * (BU2 - BU1) / (OUR2 - OUR1) + BU1.

[0063] The reaction assembly further includes: a stirrer 180; the stirrer 180 extends into the interior of the reaction chamber 100; the stirrer 180 is configured to stir the substance in the reaction chamber through its stirring end.

[0064] During the above-described implementation, the stirring action of agitator 180 ensures uniform mixing of the contents within reaction chamber 100, ensuring adequate contact between nutrients, gases, and microorganisms. By increasing the turbulence of the liquid, agitator 180 improves the efficiency of gas exchange and material transfer, particularly the transfer of dissolved oxygen and carbon dioxide, which helps meet the needs of cell growth and metabolic activity. During certain biological reactions, reactants may precipitate or agglomerate. The stirring action of agitator 180 prevents this phenomenon.

[0065] For details, please see Figure 3 , Figure 3 A schematic diagram of a tangential air intake cross section provided in an embodiment of the present application.

[0066] The air inlet assembly also includes: a second pipe 150; the end of the second pipe 150 close to the reaction assembly is connected to the air inlet end 110 of the reaction device; the second pipe 150 is used to input gas into the reaction assembly; the first pipe 130 is connected to the side wall of the second pipe 150 along the tangential direction of the second pipe 150.

[0067] In the above implementation process, when the first pipe 130 is connected to the side wall of the second pipe 150 along the tangential direction of the second pipe 150, the gas entering the second pipe 150 will be in the tangential direction, which helps to break the static gas layer in the second pipe 150, and form a rotating airflow in the second pipe 150 to promote the uniform distribution of the gas, so that the contact between the gases is more sufficient and the mixing efficiency is improved.

[0068] In summary, in the several embodiments provided in this application, it should be understood that the disclosed devices can also be implemented in other ways. The device embodiments described above are merely schematic. For example, the block diagrams in the accompanying drawings show the possible architecture, functions and operations of the devices according to the multiple embodiments of the present application. In this regard, each box in the block diagram can represent a module, a program segment or a part of a code, and the module, program segment or a part of the code contains one or more executable instructions for implementing the specified logical function. It should also be noted that in some alternative implementations, the functions marked in the box can also occur in an order different from that marked in the accompanying drawings. For example, two consecutive boxes can actually be executed substantially in parallel, and they can sometimes be executed in the opposite order, depending on the functions involved. It should also be noted that each box in the block diagram, and the combination of the block diagrams, can be implemented with a dedicated hardware-based system that performs the specified function or action, or can be implemented with a combination of dedicated hardware and computer instructions.

[0069] The foregoing is merely an embodiment of the present application and is not intended to limit the scope of protection of the present application. Various modifications and variations are possible for those skilled in the art. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present application shall be included within the scope of protection of the present application. It should be noted that similar reference numerals and letters represent similar items in the following figures. Therefore, once an item is defined in one figure, it does not need to be further defined or explained in subsequent figures.

[0070] The above is only a specific implementation method of the present application, but the scope of protection of the present application is not limited thereto. Any technician familiar with this technical field can easily think of changes or replacements within the technical scope disclosed in this application, which should be covered by the scope of protection of the present application.

[0071] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article, or device comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or elements inherent to such process, method, article, or device. In the absence of further limitations, the elements defined by the phrase "comprising..." do not exclude the presence of other identical elements in the process, method, article, or device comprising the elements.

Claims

1. A reaction device, characterized in that: include: Reaction components and detection components; The reaction assembly includes: a reaction chamber, an air inlet end, and an air outlet end; the reaction chamber is connected to the air inlet end and the air outlet end respectively; the reaction chamber is configured to provide a reaction site for a physical and chemical reaction; the air inlet end and the air outlet end are configured to provide a passage for gas flowing through the reaction chamber; The detection assembly includes: a first detection element, a second detection element and a third detection element; the first detection element is arranged at the air inlet end; the second detection element is arranged inside the reaction chamber; the third detection element is arranged at the air outlet end; the first detection element, the second detection element and the third detection element are configured to monitor the material properties at their locations.

2. The reaction equipment according to claim 1, characterized in that The reaction equipment further comprises: an air intake assembly; The air inlet component is connected to the air inlet end of the reaction component, and includes: a first pipeline and a flow controller; The first pipeline is configured to pass gas into the reaction component; the flow controller is provided at an end of the first pipeline close to the reaction component; the flow controller is configured to control the flow rate of gas in the first pipeline; Wherein, the gas includes a single gas and / or a mixed gas.

3. The reaction equipment according to claim 2, characterized in that The air intake assembly further includes: a second pipe; The end of the second pipe close to the reaction component is connected to the gas inlet end of the reaction component; the second pipe is used to input the gas into the reaction component; The first pipe is connected to the side wall of the second pipe along a tangent direction of the second pipe.

4. The reaction equipment according to claim 3, characterized in that The first detection element is connected to the interior of the second pipe; The first detection element includes: a first oxygen sensor and a first carbon dioxide sensor; The first oxygen sensor is configured to detect the oxygen content in the gas passing into the intake end; the first carbon dioxide sensor is configured to detect the carbon dioxide content in the gas passing into the intake end.

5. The reaction equipment according to claim 1, characterized in that The second detection element includes at least one of a weight sensor, a temperature sensor, a pH sensor, and a second oxygen sensor; The weight sensor is configured to detect the weight of the reactants undergoing a physical and chemical reaction inside the reaction chamber; the temperature sensor is configured to detect the temperature of the reactants undergoing a physical and chemical reaction inside the reaction chamber; the pH sensor is configured to detect the pH value of the reactants undergoing a physical and chemical reaction inside the reaction chamber; and the second oxygen sensor is configured to detect the dissolved oxygen content of the reactants undergoing a physical and chemical reaction inside the reaction chamber.

6. The reaction equipment according to claim 1, characterized in that The reaction equipment further comprises: a third pipe and a heater; The third pipeline is connected to the gas outlet end of the reaction component; the third pipeline is configured to transmit the processed gas to an external device; The heater is disposed adjacent to the third pipe; the heater is configured to heat the third pipe based on heat transfer.

7. The reaction equipment according to claim 6, characterized in that The third detection element is arranged inside the third pipe; The third detection element includes: a third oxygen sensor and a third carbon dioxide sensor; The third detection element is configured to detect the content of each gas component in the gas entering the gas outlet; wherein the content of each gas component includes oxygen content and carbon dioxide content; The third oxygen sensor is configured to detect the oxygen content in the gas passing into the gas outlet; the third carbon dioxide sensor is configured to detect the carbon dioxide content in the gas passing into the gas outlet.

8. The reaction equipment according to claim 1, characterized in that The reaction equipment further comprises: a feeding component; The feeding component is used to make compensation to the reaction chamber based on substances detected by the first detection element, the second detection element, and the third detection element.

9. The reaction equipment according to claim 8, characterized in that The feeding component includes: a feeding container and a feeding controller; The feeding container is connected to the reaction chamber, and the feeding container is configured to place reactants related to the physical and chemical reactions in the reaction chamber; wherein the reactants include biological culture media of the related physical and chemical reactions; The feed controller is configured to adjust a rate at which the reactants in the feed container are delivered to the reaction chamber.

10. The reaction equipment according to claim 1, characterized in that The reaction assembly further comprises: a stirrer; The stirrer extends into the interior of the reaction chamber; the stirrer is configured to stir the material in the reaction chamber through its stirring end.

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