Analyzing apparatus
By designing the liquid inlet and outlet of the sample pool in the analysis equipment to achieve unidirectional liquid flow, the problem of cumbersome sample replacement in traditional nanoparticle analyzers is solved, the operation process is simplified, the sample pool position is kept fixed, and the analysis efficiency is improved.
Patent Information
- Application Number
- CN202422537908.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-18
- Publication Date
- 2025-09-05
- Estimated Expiration
- 2034-10-18
AI Technical Summary
Traditional nanoparticle analyzers are cumbersome to operate when changing different samples, and the sample pool needs to be removed from the analyzer for cleaning.
An analytical device is designed. The sample pool has a liquid inlet and a liquid outlet. The liquid flows in one direction. The cleaning liquid is injected through the liquid inlet and the waste liquid is discharged through the liquid outlet, which simplifies the sample replacement process.
The sample can be replaced without removing the sample cell, reducing tedious operations and keeping the sample cell in a fixed position, making it easier to compare analysis results.
Smart Images

Figure CN223308050U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of analysis equipment, in particular to an analysis equipment. Background Art
[0002] Traditional nanoparticle analyzers, such as laser particle size analyzers, primarily rely on light scattering to analyze particle size. Despite their high accuracy and stability, they still face numerous challenges in practical application. For example, the sample cell is designed with a single outlet, requiring the cell to be removed from the analyzer for cleaning when switching between different samples, a cumbersome operation. Utility Model Content
[0003] The main purpose of the utility model is to provide an analysis device, aiming to solve the problem of complicated operation when analyzing different samples.
[0004] To achieve the above-mentioned purpose, the analytical equipment proposed by the present invention includes:
[0005] a rack having a mounting surface;
[0006] a sample cell having a liquid inlet and a liquid outlet, wherein the liquid in the sample cell enters the sample cell through the liquid inlet and is discharged through the liquid outlet, and the sample cell is used to receive a laser beam, wherein the laser beam is arranged perpendicular to the mounting plane; and
[0007] An image acquisition module is installed on the installation plane and is used to collect image information of the sample in the sample pool.
[0008] In one embodiment, the sample pool is tilted relative to the installation plane.
[0009] In one embodiment, the analysis device further comprises an inclined seat, which is disposed on the mounting plane and has an inclined surface, which is disposed at a preset angle to the mounting plane, and the sample pool is mounted on the inclined surface.
[0010] In one embodiment, the angle between the inclined surface and the mounting plane is 10±5 degrees;
[0011] and / or, the tilting seat is detachably connected to the mounting plane;
[0012] And / or, the liquid inlet and the liquid outlet are arranged from low to high along the inclined direction of the sample pool.
[0013] In one embodiment, the analysis device further comprises a moving component, wherein the moving component is mounted on the mounting plane, the sample pool is mounted on the moving component, and the moving component is used to drive the sample pool.
[0014] In one embodiment, the moving assembly includes a guide rail fixed on the installation plane, a slide mounted on the guide rail, and a driving member for driving the slide to move, wherein the slide is used for mounting the sample cell.
[0015] In one embodiment, the analysis device further comprises a laser module and an optical path conducting structure mounted on the rack, wherein the laser module is used to emit a laser beam, and the optical path conducting structure is used to receive the laser beam emitted by the laser module and conduct it to the sample pool.
[0016] In one embodiment, the laser module is disposed above the sample cell;
[0017] The optical path transmission structure includes a reflector, a first lens, and a second lens. The reflector is used to reflect the laser beam emitted by the laser module so that the laser beam passes through the first lens and the second lens in sequence and reaches the sample cell.
[0018] The first lens is used to improve the quality of the light beam;
[0019] The second lens is used to compress the laser beam so that the laser beam forms a light sheet.
[0020] In one embodiment, the light path conducting structure further comprises an adjustment frame, the reflector is mounted on the adjustment frame, and the adjustment frame is used to adjust the angle of the reflector;
[0021] And / or, the reflector is configured as a plane mirror with a reflection angle of 45 degrees, the first lens is configured as a convex lens, and the second lens is configured as a concave lens.
[0022] In one embodiment, the analysis device further comprises a microscope objective module, and the image acquisition module collects image information of the sample in the sample pool through the microscope objective module;
[0023] And / or, the liquid inlet and the liquid outlet of the sample cell are connected to a liquid inlet pipe and a liquid outlet pipe respectively.
[0024] The technical solution of the present invention adopts a sample pool with a liquid inlet and a liquid outlet. The liquid in the sample pool enters through the liquid inlet and is discharged through the liquid outlet. At this time, the sample in the sample pool flows in one direction, and the flow direction is from the liquid inlet toward the liquid outlet. When the analysis equipment of the present application analyzes different samples and needs to replace the sample, there is no need to remove the sample pool from the rack. It is only necessary to flush the sample pool and then inject the new sample into the sample pool, thereby solving the technical problems existing in the prior art. BRIEF DESCRIPTION OF THE DRAWINGS
[0025] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying any creative work.
[0026] Figure 1 A schematic structural diagram of an embodiment of an analysis device provided by the present utility model;
[0027] Figure 2 for Figure 1 Schematic diagram of the structure inside the rack of the analytical equipment;
[0028] Figure 3 for Figure 2 A magnified view of part of the structure of the analytical equipment;
[0029] Figure 4 for Figure 2 A schematic side view of the analytical equipment;
[0030] Figure 5 for Figure 1 Schematic diagram of the structure of the sample pool in the analysis equipment.
[0031] Description of Figure Numbers:
[0032] 100, rack; 110, mounting surface;
[0033] 200, sample cell; 210, liquid inlet pipe; 220, liquid outlet pipe;
[0034] 300. Image acquisition module;
[0035] 400, inclined seat; 410, inclined surface;
[0036] 500, moving assembly; 510, guide rail; 520, slide; 530, driving member;
[0037] 600, laser module;
[0038] 700, optical path transmission structure; 710, reflector; 720, first lens; 730, second lens; 740, adjustment frame;
[0039] 800. Microscope objective lens module.
[0040] The realization of the purpose, functional features and advantages of the present invention will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION
[0041] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts shall fall within the scope of protection of the present invention.
[0042] It should be noted that if the embodiments of the present invention involve directional indications (such as up, down, left, right, front, back, etc.), the directional indications are only used to explain the relative position relationship, movement status, etc. between the components in a certain specific posture. If the specific posture changes, the directional indications will also change accordingly.
[0043] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present invention, the descriptions of "first", "second", etc. are only for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features limited to "first" and "second" may explicitly or implicitly include at least one of such features. In addition, if "and / or" or "and / or" appears in the full text, its meaning includes three parallel schemes. Taking "A and / or B" as an example, it includes scheme A, or scheme B, or a scheme in which A and B are satisfied at the same time. In addition, the technical solutions between the various embodiments can be combined with each other, but it must be based on the ability of ordinary technicians in this field to implement. When the combination of technical solutions is mutually contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.
[0044] Traditional nanoparticle analyzers, such as laser particle size analyzers, primarily rely on light scattering to analyze particle size. Despite their high accuracy and stability, they still face numerous challenges in practical application. For example, the sample cell is designed with a single outlet, requiring the cell to be removed from the analyzer for cleaning when switching between different samples, a cumbersome operation.
[0045] The utility model provides an analysis device that can solve the problem of complicated operations when analyzing different samples.
[0046] See also Figure 1 、 Figure 2 In one embodiment of the present invention, the analysis device comprises:
[0047] The rack 100 has a mounting surface 110 .
[0048] The sample pool 200 has a liquid inlet (not shown) and a liquid outlet (not shown). The liquid (sample) in the sample pool 200 enters from the liquid inlet and is discharged from the liquid outlet. That is to say, in this embodiment, the sample in the sample pool 200 flows in one direction, and the flow direction is from the liquid inlet toward the liquid outlet. Furthermore, in this embodiment, a one-way flow valve body can be provided at the liquid inlet and the liquid outlet to achieve the above operation. When the analysis device of the present application is analyzing different samples and needs to replace the sample, it is not necessary to remove the sample pool 200 from the rack 100. It is only necessary to flush the sample pool 200 and then inject the new sample into the sample pool 200, thereby solving the existing The technical problems existing in the technology are as follows: after sample 1 is analyzed, cleaning liquid is injected into the sample pool 200 through the liquid inlet, and sample 1 is discharged outward through the liquid outlet. In order to facilitate the collection of waste liquid for analysis, a waste liquid collection device can be designed at the liquid outlet, and the discharged waste liquid, that is, sample 1, can directly enter the waste liquid collection device. After sample 1 is discharged from the sample pool 200, sample 2 to be analyzed can be injected into the sample pool 200 through the liquid inlet. Such operation can reduce the tedious operation of removing the sample pool 200 from the rack 100, and can also ensure that when multiple samples are analyzed, the position of the sample pool 200 remains fixed, which is convenient for subsequent comparison of analysis results.
[0049] The sample cell 200 is used to receive a laser beam, which is arranged perpendicular to the mounting plane 110. It goes without saying that the analysis device of this embodiment may be provided with a laser. In this case, the laser beam emitted by the laser is arranged perpendicular to the mounting plane 110 and irradiates the sample cell 200. In other embodiments, the analysis device may not be equipped with a laser, and the laser may be installed on other structures. In this case, the laser beam emitted by the laser is arranged perpendicular to the mounting plane 110 and irradiates the sample cell 200. Furthermore, in this embodiment, when the sample cell 200 is horizontally mounted on the mounting plane 110, the laser beam emitted by the laser will irradiate the sample in the sample cell 200 perpendicularly. When the sample cell 200 is tilted on the mounting plane 110, there is an acute angle between the laser beam emitted by the laser and the sample plane in the sample cell 200, and the angle between the laser beam and the sample plane in the sample cell 200 will change as the tilt of the sample cell 200 changes.
[0050] The image acquisition module 300 is mounted on the mounting plane 110 to collect image information of the sample in the sample pool 200. That is, the image acquisition module 300 is located on one side of the sample pool 200 and can obtain image information of the sample in the sample pool 200 through the side of the sample pool 200. Furthermore, in this embodiment, the mounting plane 110 in the rack 100 can be a single entire plane or a plurality of stepped planes. The image acquisition module 300 can be configured as a camera to obtain image information of the sample in the sample pool 200. After the image information of the sample is obtained, it can be transmitted to a display device (computer) for display. If the image information needs to be transmitted to a display device, the image acquisition module 300 in this embodiment also needs to be electrically connected to the display device.
[0051] In one embodiment, reference Figure 1 、 Figure 4 The sample cell 200 is tilted relative to the mounting plane 110. This means that an acute angle exists between the laser beam and the sample plane in the sample cell 200. As the tilt angle of the sample cell 200 changes, the angle between the sample plane in the sample cell 200 and the laser beam also changes. Because the sample cell 200 is tilted relative to the mounting plane 110, the laser beam irradiating the sample cell 200 at this time provides more accurate image information of the particle concentration and particle number density in the sample cell 200, resulting in better analytical and detection performance for the analytical device.
[0052] Furthermore, in one embodiment, referring to Figure 1 、 Figure 3 The analysis device further includes a tilting seat 400, which is disposed on the mounting plane 110. The tilting seat 400 has an inclined surface 410, which is arranged at a preset angle to the mounting plane 110. The sample pool 200 is mounted on the inclined surface 410. Furthermore, the sample pool 200 is mounted on the inclined surface 410 of the tilting seat 400 by screw locking. Thus, in this embodiment, different tilting seats 400 can be replaced to adjust the tilt angle of the sample pool 200. However, the present design is not limited to this. In other embodiments, the tilt angle of the sample pool 200 can also be adjusted by other means, such as by an automatically tilting inclined plate, on which the sample pool 200 is mounted, and the tilt angle of the sample pool 200 changes according to the change in the tilt angle of the inclined plate.
[0053] In one embodiment, the angle between the inclined surface 410 and the mounting plane 110 is 10±5 degrees. Furthermore, in this embodiment, the angle is selected to be 5 degrees. However, the present design is not limited to this. Depending on different samples, the angle between the inclined surface 410 and the mounting plane 110 can also be other angles, such as 7 degrees, 10 degrees, 13 degrees, or 15 degrees. In one embodiment, the inclined seat 400 is detachably connected to the mounting plane 110. Furthermore, in this embodiment, the inclined seat 400 is detachably connected to the mounting plane 110 by screw locking. In one embodiment, the liquid inlet and the liquid outlet are arranged from low to high along the inclination direction of the sample pool 200, so that the analytical equipment can be conveniently connected to perform flow monitoring.
[0054] In one embodiment, reference Figure 1 The analysis device further includes a moving component 500, the moving component 500 is mounted on the mounting plane 110, the sample pool 200 is mounted on the moving component 500, and the moving component 500 is used to drive the sample pool 200. Further, the moving component 500 in this embodiment can drive the sample pool 200 along the first direction (see Figure 4 ) moves. Specifically, when the analysis device in this embodiment includes a tilting seat 400, the tilting seat 400 is installed on the moving component 500 by screw locking. That is to say, the moving component 500 drives the tilting seat 400 to move and then drives the sample pool 200 to move. The movement of the sample pool 200 can avoid impurities, liquid bubbles, and the best collection position can be taken according to the image quality to improve the analysis effect.
[0055] In one embodiment, reference Figure 3 The moving component 500 includes a guide rail 510 fixed to the installation plane 110, a slide 520 provided on the guide rail 510, and a driving member 530 for driving the slide 520 to move. The slide 520 is used for installing the sample pool 200. Furthermore, in this embodiment, the driving member 530 can be a linear driving structure of a cylinder or an electric telescopic cylinder. The slide 520 is driven by the driving member 530 to move along the guide rail 510 in a first direction, thereby driving the sample pool 200 to move.
[0056] In one embodiment, reference Figure 1 、 Figure 4The analysis device also includes a laser module 600 and an optical path conduction structure 700 installed on the rack 100. The laser module 600 is used to emit a laser beam. The optical path conduction structure 700 is used to receive the laser beam emitted by the laser module 600 and conduct it to the sample pool 200. Furthermore, the optical path conduction structure 700 is used to control the direction and position of the laser beam emitted by the laser module 600, so as to facilitate the installation of the laser module 600 on the rack 100. In other words, the installation position of the laser module 600 can be made more convenient and reasonable.
[0057] In one embodiment, reference Figure 4 , the laser module 600 is arranged above the sample pool 200; the optical path transmission structure 700 includes a reflector 710, a first lens 720, and a second lens 730, the reflector 710 is used to reflect the laser beam emitted by the laser module 600, so that the laser beam passes through the first lens 720 and the second lens 730 in sequence and reaches the sample pool 200, wherein the reflector 710 can be a prism or a plane mirror, wherein the reflection angle of the reflector 710 can be set according to actual needs; the first lens 720 is used to improve the quality of the light beam, thereby improving the accuracy of the analysis equipment; the second lens 730 is used to compress the laser beam, so that the laser beam forms a light sheet, so that high-quality laser light is provided to the sample pool 200.
[0058] In one embodiment, the optical path conduction structure 700 further includes an adjustment frame 740, and the reflector 710 is mounted on the adjustment frame 740. The adjustment frame 740 is used to adjust the angle of the reflector 710. Furthermore, according to different reflectors 710 (prisms or plane mirrors), their reflection angles can be adjusted through the adjustment frame 740.
[0059] In one embodiment, the reflector 710 is configured as a plane mirror with a reflection angle of 45 degrees. The reflector 710 is adjusted to 45 degrees by the adjustment frame 740 to control the direction of the laser beam emitted by the laser module 600, ensuring that the laser beam can accurately pass through the first lens 720 and the second lens 730 and then irradiate the liquid in the sample cell 200. The first lens 720 is configured as a convex lens, and the second lens 730 is configured as a concave lens. The convex lens can focus the incident parallel or nearly parallel laser beam to a point, or converge the divergent light from a distance, thereby improving the beam quality. Then, the concave lens can convert the light converged by the convex lens into parallel light, so that it forms a light sheet, and finally irradiates the sample cell 200. However, the present design is not limited to this. In other embodiments, the reflector 710 is configured as a prism.
[0060] In one embodiment, reference Figure 2The analysis device also includes a microscope objective module 800. The image acquisition module 300 collects image information of the sample in the sample pool 200 through the microscope objective module 800. Under the action of the microscope objective module 800, the particle size information collected by the image acquisition module 300 can be made more detailed, thereby further improving the image quality.
[0061] In one embodiment, the liquid inlet and the liquid outlet of the sample pool 200 are respectively connected to a liquid inlet pipe 210 and a liquid outlet pipe 220, so as to facilitate the injection of liquid into the sample pool 200 and the discharge of liquid from the sample pool 200. Furthermore, in this embodiment, the liquid inlet pipe 210 and the liquid outlet pipe 220 are configured as silicone hoses.
[0062] The above description is merely an exemplary embodiment of the present invention and does not limit the patent scope of the present invention. All equivalent structural transformations made using the contents of the present invention specification and drawings under the technical concept of the present invention, or direct / indirect application in other related technical fields are included in the patent protection scope of the present invention.
Claims
1. An analytical device, characterized in that include: a rack having a mounting surface; A sample cell having a liquid inlet and a liquid outlet, wherein the liquid in the sample cell enters the sample cell through the liquid inlet and is discharged through the liquid outlet, and the sample cell is used to receive a laser beam, and the laser beam is arranged perpendicular to the mounting plane; as well as An image acquisition module is installed on the installation plane and is used to collect image information of the sample in the sample pool.
2. The analytical device according to claim 1, wherein The sample pool is arranged obliquely on the installation plane.
3. The analytical device according to claim 2, wherein The analysis device further comprises an inclined seat, which is arranged on the installation plane. The inclined seat has an inclined surface, which is arranged at a preset angle to the installation plane, and the sample pool is installed on the inclined surface.
4. The analysis device according to claim 3, wherein The angle between the inclined surface and the mounting plane is 10±5 degrees; and / or, the tilting seat is detachably connected to the mounting plane; And / or, the liquid inlet and the liquid outlet are arranged from low to high along the inclined direction of the sample pool.
5. The analysis device according to claim 1, wherein The analysis device further includes a moving component, which is installed on the installation plane. The sample pool is installed on the moving component, and the moving component is used to drive the sample pool.
6. The analysis device according to claim 5, characterized in that The moving assembly includes a guide rail fixed on the installation plane, a slide arranged on the guide rail, and a driving member for driving the slide to move. The slide is used for installing the sample pool.
7. The analysis device according to claim 1, wherein The analysis device further comprises a laser module and an optical path conducting structure installed on the frame, wherein the laser module is used to emit a laser beam, and the optical path conducting structure is used to receive the laser beam emitted by the laser module and conduct it to the sample pool.
8. The analysis device according to claim 7, wherein The laser module is arranged above the sample pool; The optical path transmission structure includes a reflector, a first lens, and a second lens. The reflector is used to reflect the laser beam emitted by the laser module so that the laser beam passes through the first lens and the second lens in sequence and reaches the sample cell. The first lens is used to improve the quality of the light beam; The second lens is used to compress the laser beam so that the laser beam forms a light sheet.
9. The analysis device according to claim 8, characterized in that The optical path conducting structure further comprises an adjusting frame, the reflector is mounted on the adjusting frame, and the adjusting frame is used to adjust the angle of the reflector; And / or, the reflector is configured as a plane mirror with a reflection angle of 45 degrees, the first lens is configured as a convex lens, and the second lens is configured as a concave lens.
10. The analysis device according to claim 1, wherein The analysis device further includes a microscope objective module, and the image acquisition module collects image information of the sample in the sample pool through the microscope objective module; And / or, the liquid inlet and the liquid outlet of the sample cell are connected to a liquid inlet pipe and a liquid outlet pipe respectively.