Sealed clamping structure and sterile liquid transfer system

The design of a sealed snap-in structure solves the problems of high interface cost and non-reusability in existing liquid sterile transportation, achieves the sealing and reusability of sterile liquid transmission, reduces costs and improves safety.

CN223331326UActive Publication Date: 2025-09-12BEIJING NEOCURNA BIOTECHNOLOGY CORP +2
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Patent Information

Application Number
CN202422657020.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-31
Publication Date
2025-09-12
Estimated Expiration
2034-10-31

AI Technical Summary

Technical Problem

Among the existing liquid aseptic transportation methods, RTP rapid transfer technology is inconvenient to install and has high consumable costs, and VHP sterilization transfer windows have a long sterilization time and pose a potential risk of contamination to the container, making it impossible to achieve a cost-effective and reusable sealing structure.

Method used

A sealed clamping structure is designed, including a joint assembly, a chuck, a clamp assembly and a sealing ring. The sealing ring realizes a sealed connection between the joint assembly and the chuck, allowing the joint assembly and the chuck to be isolated from the external environment, and can be sterilized after disassembly to achieve reuse.

Benefits of technology

It achieves the sealing and reusability of sterile liquid transmission, reduces the cost of the interface and the dependence on consumables, and improves the efficiency and safety of sterile transportation.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a sealed clamping structure and a sterile liquid transfer system, and belongs to the technical field of sterile liquid transportation, the sealed clamping structure comprises a connector assembly, a chuck, a hoop assembly and a sealing ring, the chuck is provided with a connector groove, a channel is arranged in the connector assembly, at least part of the connector assembly is arranged in the connector groove, and the channel is communicated with the connector groove; the sealing ring is arranged between the connector assembly and the chuck, the connector assembly and the chuck are sleeved with the hoop assembly, the outer wall of the sealing ring abuts against the connector assembly and the chuck, and the connector assembly is in flexible sealing connection with the chuck through the sealing ring. During disassembly, the hoop assembly is disassembled, and then the connector assembly and the chuck are disassembled; when the sealing type clamping structure needs to be used, the connector assembly and the chuck are sterilized, so that the sealing type clamping structure can be recycled and repeatedly used, and the problem that an existing connector for liquid sterile transportation cannot be repeatedly used after being sealed is solved.
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Description

Technical Field

[0001] The utility model relates to the technical field of liquid aseptic transportation, in particular to a sealed clamping structure and an aseptic liquid delivery system. Background Art

[0002] Currently, there are three main methods for aseptic transport of liquids: (1) RTP rapid transfer technology, which uses RTP to connect the isolator to the sterile environment, transfer the sterilization filter back end into the isolator, and connect the sterilization filter front end to the container containing the liquid under background conditions, and then transfer the liquid into the isolator after sterilization filtration. (2) SART aseptic transfer system, which uses SART components to connect the isolator to the sterile environment, transfer the sterilization filter back end into the isolator, and connect the sterilization filter front end to the container containing the liquid under background conditions, and then transfer the liquid into the isolator after sterilization filtration. (3) VHP sterilization transfer window, which performs surface decontamination on the container containing the liquid and then transfers it into the isolator operation area, and then performs sterilization filtration in the isolator.

[0003] In the aforementioned sterile transport of liquids, RTP rapid transfer technology requires a large amount of installation space, making it difficult to install in small isolators. The assembly cost of RTP itself is high, and the cost of the disposable consumables it requires is also relatively high and cannot be reused.

[0004] However, hydrogen peroxide sterilization of VHP sterilization transfer windows requires a longer sterilization time. Hydrogen peroxide vapor has a certain degree of penetration into some packaging container materials, and there is a potential risk of contamination when sterilizing containers containing liquids. VHP sterilization has certain limitations. It has a good decontamination effect on the surface of objects, but has poor decontamination ability on relatively complex surfaces. It has a potential sterility risk and cannot be used for some liquid materials that need to be transferred continuously.

[0005] Therefore, how to achieve a cost-effective and reusable sealing structure in the aseptic liquid transfer of the aseptic liquid transfer system is particularly important. Summary of the Invention

[0006] The purpose of the utility model is to improve the problem that the existing interface for aseptic liquid transportation cannot be reused after being sealed, and to provide a sealed clamping structure and an aseptic liquid transfer system.

[0007] The technical solutions to achieve the above objectives include the following:

[0008] Sealed snap-fit ​​structure, including:

[0009] A joint assembly, a chuck, a clamp assembly, and a sealing ring, wherein the chuck is provided with a joint groove, the joint assembly has a channel therein, at least a portion of the joint assembly is disposed in the joint groove, and the channel is in communication with the joint groove;

[0010] The sealing ring is arranged between the joint assembly and the chuck, the clamp assembly is sleeved on the outside of the joint assembly and the chuck, the outer wall of the sealing ring is respectively against the joint assembly and the chuck, and the joint assembly is sealed and connected to the chuck through the sealing ring.

[0011] In one embodiment, the joint assembly includes a main body and at least a first joint member and a second joint member, wherein the first joint member and the second joint member are respectively installed on both sides of the main body so that the joint assembly forms a cross structure;

[0012] The inner cavity of the first connector is connected to the inner cavity of the second connector to form the channel;

[0013] The sealing ring is arranged between the main body and the chuck.

[0014] In one embodiment, a groove is formed on a side of the main body close to the chuck, and / or a groove is formed on a side of the chuck close to the main body;

[0015] The groove is extended along the circumference of the main body or the chuck, and the sealing ring is at least partially accommodated in the groove.

[0016] In one embodiment, the clamp assembly includes a first clamping member and a second clamping member, wherein the first end of the first clamping member is rotatably connected to the first end of the second clamping member, and the second end of the first clamping member is detachably engaged with the second end of the second clamping member;

[0017] A locking position is formed between the inner side of the first locking member and the inner side of the second locking member, and the connector assembly and the chuck are arranged in the locking position.

[0018] In one embodiment, the clamp assembly further includes a connecting plate, a screw, and an adjusting bolt. The first ends of the first engaging member and the second engaging member are both rotatably connected to the connecting plate. The first end of the screw is mounted on the second end of the second engaging member. The second end of the first engaging member is for the second end of the screw to pass through. The adjusting bolt is sleeved on the outside of the screw and cooperates with the screw thread. The adjusting bolt is used to abut against the first engaging member.

[0019] In one embodiment, the first engaging member and the second engaging member have inner sides with a slot, and the connector assembly and the chuck are at least partially accommodated in the slot and abut against the bottom wall of the slot.

[0020] In one embodiment, the clamping structure further includes an isolation hatch, the isolation hatch is provided with an opening, the first end of the chuck is provided at the opening, and the joint groove of the chuck is communicated with the opening;

[0021] The first end of the chuck is sealed to the isolation cabin door, and the second end of the chuck is sealed to the joint assembly.

[0022] The present invention further provides a sterile liquid transfer system, comprising a housing, a first container, a second container, a sterilizing filter assembly, and the sealed snap-fit ​​structure described above, wherein an isolation door of the sealed snap-fit ​​structure is installed in the housing and separates the housing into a first compartment and a second compartment, wherein the first container is disposed in the first compartment, and the second container is disposed in the second compartment;

[0023] The first container, the sterilizing filter assembly, and the first end of the sealed clamping structure are connected in series in sequence;

[0024] The second end of the sealed clamping structure is connected to the second container.

[0025] In one embodiment, the sterile liquid transfer system includes a first connecting tube and a second connecting tube. The first container and the sterilization filtration assembly are connected in series through the first connecting tube. The first connecting tube is connected to the first end of the connector assembly. The second end of the connector assembly is connected to the first end of the second connecting tube. The second end of the second connecting tube is connected to the second container.

[0026] In one embodiment, the sterile liquid transfer system further includes a pressure relief valve and a liquid pump, wherein the pressure relief valve is communicated with the first container, and the liquid pump is connected to the first connecting pipe.

[0027] The technical solution provided by the utility model has the following advantages and effects:

[0028] A sealing ring seals the connector assembly and the chuck, isolating them from the external environment and effectively isolating the first and second compartments. Furthermore, the connector assembly's channel communicates with the connector slot of the chuck, enabling the transfer of sterile liquids. During disassembly, the clamp assembly is removed, followed by the connector assembly and chuck. When needed, the connector assembly and chuck are sterilized. This sealed clamping structure is reusable, improving existing issues with the high cost of interfaces for sterile liquid transport and the high dependency of associated consumables on these interfaces. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] The accompanying drawings herein illustrate specific examples of the technical solutions described in the present invention, and together with the specific implementation methods constitute a part of the specification, and are used to explain the technical solutions, principles and effects of the present invention.

[0030] Unless otherwise specified or defined, the same reference numerals in different drawings represent the same or similar technical features, and the same or similar technical features may also be represented by different reference numerals.

[0031] Figure 1 This is a schematic diagram of a sealed clamping structure in one embodiment of the present invention;

[0032] Figure 2 In one embodiment of the present utility model Figure 1 A local enlarged view of point A;

[0033] Figure 3 It is a schematic diagram of a clamp assembly in one embodiment of the present utility model;

[0034] Figure 4 is a schematic diagram of a sterile liquid delivery system in one embodiment of the present invention;

[0035] Description of reference numerals:

[0036] 100. Sealed clamping structure;

[0037] 1. Isolation hatch; 11. Opening; 2. Connector assembly; 21. Main body; 22. First connector; 23. Second connector; 24. Passageway; 25. Groove; 3. Chuck; 31. Connector slot; 4. Clamp assembly; 40. Engagement position; 41. First engaging member; 42. Second engaging member; 43. Connecting plate; 44. Slot; 45. Screw; 46. Adjustment bolt; 5. Sealing ring;

[0038] 200. Sterile liquid delivery system;

[0039] 6. Box body; 61. First cabin; 62. Second cabin; 7. First container; 71. First connecting pipe; 8. Second container; 81. Second connecting pipe; 9. Sterile filtration assembly; 10. Pressure relief valve. DETAILED DESCRIPTION

[0040] In order to facilitate the understanding of the present invention, specific embodiments of the present invention will be described in more detail below with reference to the accompanying drawings.

[0041] Unless otherwise specified or defined, the "first, second..." used in this article is only used to distinguish names and does not represent a specific quantity or order.

[0042] Unless stated otherwise or defined otherwise, the term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0043] It should be noted that when an element is considered to be "fixed to" another element, it can be directly fixed to the other element or there can be an intermediate element; when an element is considered to be "connected to" another element, it can be directly connected to the other element or there can be an intermediate element; when an element is considered to be "mounted on" another element, it can be directly mounted on the other element or there can be an intermediate element. When an element is considered to be "located on" another element, it can be directly located on the other element or there can be an intermediate element.

[0044] The present invention proposes a sealed clamping structure 100, such as Figure 1 and Figure 2 As shown, it includes: a joint assembly 2, a chuck 3, a clamp assembly 4, and a sealing ring 5. The chuck 3 is provided with a joint groove 31, and the joint assembly 2 has a channel 24. At least part of the joint assembly 2 is arranged in the joint groove 31, and the channel 24 is connected to the joint groove 31; the sealing ring 5 is arranged between the joint assembly 2 and the chuck 3, and the clamp assembly 4 is sleeved on the outside of the joint assembly 2 and the chuck 3. The outer walls of the sealing ring 5 are respectively against the joint assembly 2 and the chuck 3, and the joint assembly 2 is flexibly sealed and connected to the chuck 3 through the sealing ring 5.

[0045] Specifically, when using the sealed clamping structure 100, the chuck 3 is fixed to the isolation hatch 1, and the sealing ring 5 is then positioned between the joint assembly 2 and the chuck 3. The joint assembly 2 and the chuck 3 are then fastened together by the clamp assembly 4. The sealing ring 5 is elastic and is squeezed by the joint assembly 2 and the chuck 3, achieving a sealed connection between the joint assembly 2 and the chuck 3 via the sealing ring 5, isolating the joint assembly 2 and the chuck 3 from the external environment. Furthermore, the channel 24 of the joint assembly 2 communicates with the joint groove 31 of the chuck 3. The two ends of the joint assembly 2 are used to connect to the first connecting tube 71 and the second connecting tube 81 to achieve the transmission of sterile liquid.

[0046] During disassembly, the clamp assembly 4 is removed, and then the connector assembly 2 and the chuck 3 are disassembled; when needed, the connector assembly 2 and the chuck 3 are sterilized. Therefore, this sealed clamping structure 100 can be recycled and reused, improving the problem that the existing liquid sterile transportation interface cannot be reused after sealing.

[0047] In some embodiments, as Figure 1As shown, the connector assembly 2 includes a first connector 22, a second connector 23, and a main body 21. The first connector 22 and the second connector 23 are respectively installed on both sides of the main body 21, so that the connector assembly 2 forms a cross structure. The inner cavity of the first connector 22 is connected to the inner cavity of the second connector 23, and a channel 24 is formed. The sealing ring 5 is arranged between the main body 21 and the chuck 3. Specifically, when the connector assembly 2 and the chuck 3 are sealed and connected by the clamp assembly 4, the first connector 22 of the connector assembly 2 is used to connect to the connecting pipe of the sterile environment. The liquid in the connecting pipe of the sterile environment can be aseptically treated and then flow into the first connector 22. The second connector 23 is used to connect to the connecting pipe of the sterile environment. Therefore, through the cooperation between the connector assembly 2, the chuck 3, the sealing ring 5, and the clamp 4, the liquid can be further transmitted in the sterile channel 24.

[0048] In order to improve the stability of the sealing ring 5 between the joint assembly 2 and the chuck 3. Figure 2 As shown, a groove 25 is defined on the side of the main body 21 proximal to the chuck 3, and / or a groove 25 is defined on the side of the chuck 3 proximal to the main body 21; the groove 25 extends circumferentially along the main body 21 or the chuck 3, and the sealing ring 5 is at least partially accommodated within the groove 25. In this embodiment, grooves 25 are defined on both the side of the main body 21 proximal to the chuck 3 and the side of the chuck 3 proximal to the main body 21. The sealing ring 5 is positioned within the grooves 25, so that the main body 21 and the chuck 3 respectively restrict the movement of the sealing ring 5, thereby improving the stability of the sealing ring 5 between the connector assembly 2 and the chuck 3. When the sealed snap-fit ​​structure 100 is disassembled, the sealing ring 5 can be accommodated within the grooves 25, preventing the sealing ring 5 from being lost if it falls off, thereby improving the reusability of the sealed snap-fit ​​structure 100.

[0049] In some embodiments, as Figure 3 As shown, the clamp assembly 4 includes a first engaging member 41 and a second engaging member 42. The first end of the first engaging member 41 is rotatably connected to the first end of the second engaging member 42, and the second end of the first engaging member 41 is detachably engaged with the second end of the second engaging member 42. The inner sides of the first engaging member 41 and the inner sides of the second engaging member 42 form an engaging position 40, and the connector assembly 2 and the chuck 3 are disposed in the engaging position 40. Specifically, the first engaging member 41 is rotatably connected to the first end of the second engaging member 42 to open or close the engaging position 40. When in use, open the locking position 40, place the connector assembly 2 and the chuck 3 in the locking position 40, and then fix the second ends of the first locking member 41 and the second locking member 42, so that the first locking member 41 and the second locking member 42 squeeze the outer walls of the connector assembly 2 and the chuck 3 in the locking position 40, and the connector assembly 2 and the chuck 3 are close to each other, and squeeze the sealing ring 5 to eliminate the gap between the connector assembly 2 and the chuck 3, thereby realizing the isolation of the connector groove 31 and the channel 24 from the external environment, and further realizing the sterile transportation of the liquid.

[0050] In order to facilitate the disassembly of the clamp assembly 4 and improve the sealing between the joint assembly 2 and the chuck 3, the clamp assembly 4 further includes a connecting plate 43, a screw 45, and an adjusting bolt 46. The first ends of the first engaging member 41 and the second engaging member 42 are both rotatably connected to the connecting plate 43. The first end of the screw 45 is mounted on the second end of the second engaging member 42. The second end of the first engaging member 41 is for the second end of the screw 45 to pass through. The adjusting bolt 46 is sleeved on the outside of the screw 45 and is threadedly engaged with the screw 45. The adjusting bolt 46 is used to abut against the first engaging member 41. Specifically, a connecting plate 43 is rotatably connected to the first engaging member 41 and the second engaging member 42. When the joint assembly 2 and the chuck 3 need to be placed, the second ends of the first engaging member 41 and the second engaging member 42 are opened; when the joint assembly 2 and the chuck 3 need to be closed and sealed, the adjusting bolt 46 is rotated clockwise, and the adjusting bolt 46 is threadedly engaged with the screw 45, so that the adjusting bolt 46 squeezes the second end of the first engaging member 41, and the second ends of the first engaging member 41 and the second engaging member 42 approach each other, reducing the size of the engaging position 40, thereby squeezing the joint assembly 2 and the chuck 3, and further improving the sealing between the joint assembly 2 and the chuck 3.

[0051] When the joint assembly 2 and the chuck 3 need to be disassembled, the adjusting bolt 46 is rotated counterclockwise to move the adjusting bolt 46 away from the first engaging member 41. Therefore, by rotating the adjusting bolt 46 clockwise or counterclockwise, the clamp assembly 4 can be easily disassembled and the sealing between the joint assembly 2 and the chuck 3 can be improved.

[0052] To further enhance the stability of the connector assembly 2 and the chuck 3 at the engaging position 40, the first engaging member 41 and the second engaging member 42 are provided with a slot 44 on their inner sides. The connector assembly 2 and the chuck 3 are at least partially accommodated within the slot 44 and abut against the bottom wall of the slot 44. When the clamp assembly 4 is used to secure the connector assembly 2 and the chuck 3, the connector assembly 2 and the chuck 3 are at least partially located within the slot 44, and the bottom wall of the slot 44 abuts against the connector assembly 2 and the chuck 3, thereby enhancing the stability of the connector assembly 2 and the chuck 3 at the engaging position 40.

[0053] Preferably, the sealed clamping structure 100 also includes an isolation cabin door 1, which is provided with an opening 11. The first end of the chuck 3 is provided at the opening 11, and the joint groove 31 of the chuck 3 is in communication with the opening 11. The first end of the chuck 3 is sealedly connected to the isolation cabin door 1, and the second end of the chuck 3 is sealedly connected to the joint assembly 2. Specifically, the opening 11 is provided on the isolation cabin door 1, and the chuck 3 is installed at the isolation cabin door 1. The connection method includes welding or a sealed connection. Preferably, a sealing ring is placed on the chuck to provide a flexible seal between the chuck and the isolation cabin door, thereby achieving a sealed connection between the chuck 3 and the isolation cabin door 1. Then, the joint assembly 2 is used to detachably seal the chuck 3 to achieve sterile liquid transportation between a sterile environment and a sterile environment.

[0054] The present invention also provides a sterile liquid transfer system 200, such as Figure 4 As shown, the apparatus comprises a housing 6, a first container 7, a second container 8, a sterilizing filter assembly 9, and a sealed snap-fit ​​structure 100 as described above. The isolation door 1 of the sealed snap-fit ​​structure 100 is installed within the housing 6, dividing the housing 6 into a first compartment 61 and a second compartment 62. The first container 7 is disposed within the first compartment 61, and the second container 8 is disposed within the second compartment 62. The first container 7, the sterilizing filter assembly 9, and the first end of the sealed snap-fit ​​structure 100 are sequentially connected in series; the second end of the sealed snap-fit ​​structure 100 is connected to the second container 8. Specifically, the first container 7 is used to hold a sterile liquid. After sterilization and filtration by the sterilizing filter assembly 9, the liquid flows into the sterile connector assembly 2 and then flows through the isolation door 1 into the second container 8, achieving sterilization and filtration from the potentially sterile environment of the first compartment 61 to the sterile environment of the second compartment 62. Preferably, the sterilizing filter assembly 9 can be sterilized by irradiation, steam sterilization, or other methods, without particular limitation.

[0055] Preferably, the sterile liquid transfer system 200 includes a first connecting tube 71 and a second connecting tube 81. The first container 7 and the sterilizing filter assembly 9 are connected in series via the first connecting tube 71. The first connecting tube 71 is in communication with the first end of the connector assembly 2, the second end of the connector assembly 2 is in communication with the first end of the second connecting tube 81, and the second end of the second connecting tube 81 is in communication with the second container 8. Specifically, the first connector 22 of the connector assembly 2 is used to communicate with the first connecting tube 71, and the second connector 23 of the connector assembly 2 is used to communicate with the second connecting tube 81, further enabling the liquid in the first container 7 to be transported to the second container 8 in the sterile second compartment 62 after sterilization.

[0056] Preferably, the sterile liquid delivery system 200 further includes a pressure relief valve 10 and a liquid pump. The pressure relief valve 10 is in communication with the first container 7, and the liquid pump is connected to the first connecting pipe 71. When the liquid in the first container 7 is delivered to the sterilizing filter assembly 9 through the first connecting pipe 71, a negative pressure is formed in the first container 7. Therefore, the pressure relief valve 10 is required to relieve the pressure in the first container 7 to avoid a pressure difference between the inside and outside of the first container 7. In addition, the liquid pump provides power for the flow of the liquid.

[0057] When using the sterile liquid transfer system 200, the following operating steps are involved:

[0058] Step 1: sterilize the second container 8 and the sealed clamping structure 100, and place the second container 8 in the second compartment 62;

[0059] Step 2: Sterilize the first compartment 61 and the second compartment 62 of the box body 6 to ensure that the first compartment 61 and the second compartment 62 meet the Class A cleanliness requirements of GMP;

[0060] Step 3: Wear isolation gloves and assemble the first connecting pipe 71, the sealed clamping structure 100, the second connecting pipe 81, and the second container 8;

[0061] Step 4: Open the box 6, place the first container 7 containing the liquid to be filtered and the liquid pump in the first cabin 61, connect the first container 7, the sterilizing filter assembly 9, and the first connecting pipe 71 in series, and connect the first connecting pipe 71 to the second container 8 through the sealed sealing structure 100;

[0062] Step 5: Start the liquid pump to transport the liquid from the first container 7 to the second container 8 after passing through the sterilization filter component 9.

[0063] The purpose of the above embodiments is to exemplify and deduce the technical solution of the utility model, and to fully describe the technical solution, purpose and effect of the utility model. Its purpose is to enable the public to have a more thorough and comprehensive understanding of the disclosed content of the utility model, and it does not limit the scope of protection of the utility model.

[0064] The above embodiments are not exhaustive of the present invention, and there may be many other embodiments not listed. Any replacements and improvements made without violating the concept of the present invention are within the scope of protection of the present invention.

Claims

1. Sealed clamping structure, characterized in that: include: A joint assembly, a chuck, a clamp assembly, and a sealing ring, wherein the chuck is provided with a joint groove, the joint assembly has a channel therein, at least a portion of the joint assembly is disposed in the joint groove, and the channel is in communication with the joint groove; The sealing ring is arranged between the joint assembly and the chuck, the clamp assembly is sleeved on the outside of the joint assembly and the chuck, the outer wall of the sealing ring is respectively against the joint assembly and the chuck, and the joint assembly is sealed and connected to the chuck through the sealing ring.

2. The sealed clamping structure according to claim 1, wherein: The joint assembly includes a main body and at least a first joint member and a second joint member, wherein the first joint member and the second joint member are respectively installed on both sides of the main body so that the joint assembly forms a cross structure; The inner cavity of the first connector is connected to the inner cavity of the second connector to form the channel; The sealing ring is arranged between the main body and the chuck.

3. The sealed clamping structure according to claim 2, wherein: A groove is formed on a side of the main body close to the chuck, and / or a groove is formed on a side of the chuck close to the main body; The groove is extended along the circumference of the main body or the chuck, and the sealing ring is at least partially accommodated in the groove.

4. The sealed clamping structure according to claim 1, wherein: The clamp assembly includes a first clamping member and a second clamping member, wherein the first end of the first clamping member is rotatably connected to the first end of the second clamping member, and the second end of the first clamping member is detachably engaged with the second end of the second clamping member; A locking position is formed between the inner side of the first locking member and the inner side of the second locking member, and the connector assembly and the chuck are arranged in the locking position.

5. The sealed clamping structure according to claim 4, wherein: The clamp assembly also includes a connecting plate, a screw, and an adjusting bolt. The first ends of the first engaging member and the second engaging member are both rotatably connected to the connecting plate. The first end of the screw is installed on the second end of the second engaging member. The second end of the first engaging member is for the second end of the screw to pass through. The adjusting bolt is sleeved on the outside of the screw and cooperates with the screw thread. The adjusting bolt is used to resist the first engaging member.

6. The sealed clamping structure according to claim 4, wherein: The first engaging member and the second engaging member have a slot on their inner sides. The connector assembly and the chuck are at least partially accommodated in the slot and abut against the bottom wall of the slot.

7. The sealed clamping structure according to claim 1, wherein: The clamping structure further includes an isolation hatch, the isolation hatch is provided with an opening, the first end of the chuck is provided at the opening, and the joint groove of the chuck is communicated with the opening; The first end of the chuck is sealed to the isolation cabin door, and the second end of the chuck is sealed to the joint assembly.

8. A sterile liquid delivery system, characterized in that The invention comprises a box body, a first container, a second container, a sterilizing filter assembly, and a sealed snap-fit ​​structure according to any one of claims 1 to 7, wherein an isolation door of the sealed snap-fit ​​structure is installed in the box body and separates the box body into a first compartment and a second compartment, the first container is arranged in the first compartment, and the second container is arranged in the second compartment; The first container, the sterilizing filter assembly, and the first end of the sealed clamping structure are connected in series in sequence; The second end of the sealed clamping structure is connected to the second container.

9. The sterile liquid delivery system of claim 8, wherein: The sterile liquid transfer system includes a first connecting tube and a second connecting tube. The first container and the sterilization filtration assembly are connected in series through the first connecting tube. The first connecting tube is connected to the first end of the joint assembly, the second end of the joint assembly is connected to the first end of the second connecting tube, and the second end of the second connecting tube is connected to the second container.

10. The sterile liquid delivery system of claim 8, wherein: The sterile liquid transfer system further includes a pressure relief valve and a liquid pump. The pressure relief valve is communicated with the first container, and the liquid pump is connected to the first connecting pipe.