Cosmetic eye irritation detection and analysis device

Abstract

The utility model discloses a cosmetic eye irritation detection and analysis device which comprises a base, and the right side of the top of the base is fixedly connected with an analysis device main body. Through the arrangement of the groove, the analysis device is started, the start button is pressed down to start the automatic sample dropping pipettor, after the automatic sample dropping pipettor drips a sample to a chick embryo chorioallantoic membrane in the groove under the automatic sample dropping pipettor, the stepping motor is automatically started and drives the rotating base plate to rotate by 36 degrees, and the chick embryo chorioallantoic membrane is automatically dropped into the chick embryo chorioallantoic membrane in the groove under the automatic sample dropping pipettor. The chick embryo chorioallantoic membrane in the next groove is moved to the position under the automatic sample dropwise adding pipettor for dropwise adding the sample, and a pause button is controllably pressed until the ten chick embryo chorioallantoic membranes are dropwise added completely, so that the stepping motor and the automatic sample dropwise adding pipettor stop working, and then the chick embryo chorioallantoic membranes can be covered with a preservative film for constant-temperature culture; the dripping process is automatically and quickly completed, so that the analysis efficiency is improved, the use of a user is facilitated, and the practicability of the analysis device is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of cosmetic analysis, in particular to a device for detecting and analyzing the eye irritation of cosmetics. Background Art

[0002] Eye irritation testing is a key indicator in the safety assessment of local toxicity of cosmetics. Among these, alternative eye irritation methods are currently the most developed toxicology project. The chick embryo chorioallantoic membrane, with its rich surface vascularity, can be considered a complete organism. Unlike tests conducted solely on cells, this method offers significant potential as an alternative to eye irritation testing. The chick embryo chorioallantoic membrane (CAM) test is one of the most widely used models for alternative eye irritation testing. The chorioallantoic membrane is a respiratory membrane surrounding the chick embryo. Its vascular system is intact, clear, and transparent, effectively mimicking the structure of the conjunctiva and facilitating observation. A certain amount of the test substance is directly exposed to the chick embryo chorioallantoic membrane. After a specified exposure time, changes in toxic effect indicators such as bleeding, vascular lysis, and coagulation are observed. Scoring is performed and the mathematical mean is calculated to assess the eye irritation potential of the test substance. The chick embryo chorioallantoic membrane (CAM) test involves opening the shell, tearing the membrane, placing the ring, photographing, adding the sample, incubating at a constant temperature, photographing and recording the results, and analyzing the results. Consequently, the test process is complex and complex.

[0003] The existing analysis device requires the experimenter to manually add the sample to the chicken embryo chorioallantoic membrane detection area, cover it with plastic wrap, and then place it in a constant temperature box to keep it warm. Then, the sample is added to the next chicken embryo chorioallantoic membrane detection area. A set of tests requires 10 repeated addition processes, resulting in low analysis efficiency, inconvenience for users, and reduced practicality of the analysis device. Utility Model Content

[0004] In order to solve the problems raised in the above-mentioned background technology, the purpose of the present utility model is to provide a cosmetic eye irritation detection and analysis device, which has the advantage of high analysis efficiency and solves the problem that the existing analysis device requires the experimenter to manually add the sample to the chicken embryo chorioallantoic membrane detection area, cover it with plastic wrap, and then place it in a constant temperature box for insulation, and then add the sample to the next chicken embryo chorioallantoic membrane detection area. A set of tests requires 10 repeated addition processes, resulting in low analysis efficiency.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solution: a cosmetic eye irritation detection and analysis device, comprising a base, an analysis device body is fixedly connected to the right side of the top of the base, a motor slot is provided on the surface of the base, a stepper motor is fixedly connected to the bottom wall of the motor slot, the output end of the stepper motor is fixedly connected to a rotating chassis, the rotating chassis is located at the top of the base, and ten grooves are provided on the surface of the rotating chassis, and the grooves are in a circular array; an automatic dripping sample pipette is provided on the right side of the top of the base, a small compression pump is provided on the right side of the top of the base, the small compression pump is located on the rear side of the automatic dripping sample pipette, the output end of the small compression pump is connected to the automatic dripping sample pipette, a switch button is provided on the left side of the base, a start button and a pause button are respectively provided on the right side of the base, and the right side of the base is electrically connected to a power cord.

[0006] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0007] 1. The utility model is provided with groove, turn on the switch button and open analyzing device, and press the start button and the automatic dripping sample pipette is started, after the automatic dripping sample pipette adds sample dropwise to the chicken embryo chorioallantoic membrane in the groove directly below, the stepping motor starts automatically, and drives the rotating chassis to rotate 36 °, the chicken embryo chorioallantoic membrane in next groove inside is moved to the dripping sample directly below the automatic dripping sample pipette, until ten chicken embryo chorioallantoic membranes are all completed and dripping is controlled to press the pause button, stepping motor and the automatic dripping sample pipette are suspended, just can carry out covering preservative film constant temperature cultivation, the dropping process is automatically completed quickly, and then improved analysis efficiency, facilitated the use of user, improved the practicality of analyzing device. BRIEF DESCRIPTION OF THE DRAWINGS

[0008] Figure 1 This is a schematic diagram of the main structure of the utility model;

[0009] Figure 2 This is a schematic front view cross-sectional diagram of the structure of the utility model;

[0010] Figure 3 This is a rear view schematic diagram of the structure of the utility model;

[0011] Figure 4 It is a schematic top view cross-sectional diagram of the structure of the utility model.

[0012] In the figure: 1. Base; 2. Analyzer body; 3. Motor slot; 4. Stepper motor; 5. Rotating chassis; 6. Groove; 7. Automatic sample addition pipette; 8. Small compression pump; 9. Switch button; 10. Start button; 11. Pause button; 12. Power cord. DETAILED DESCRIPTION

[0013] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0014] like Figures 1 to 4 As shown, a cosmetic eye irritation detection and analysis device includes a base 1, an analysis device body 2 is fixedly connected to the right side of the top of the base 1, a motor slot 3 is provided on the surface of the base 1, a stepping motor 4 is fixedly connected to the bottom wall of the motor slot 3, and the output end of the stepping motor 4 is fixedly connected to a rotating chassis 5, which is located at the top of the base 1, and ten grooves 6 are provided on the surface of the rotating chassis 5, and the grooves 6 are in a circular array. An automatic dripping sample pipette 7 is provided on the right side of the top of the base 1, a small compression pump 8 is provided on the right side of the top of the base 1, the small compression pump 8 is located on the rear side of the automatic dripping sample pipette 7, and the output end of the small compression pump 8 is connected to the automatic dripping sample pipette 7, a switch button 9 is provided on the left side of the base 1, and a start button 10 and a pause button 11 are respectively provided on the right side of the base 1, and a power cord 12 is electrically connected to the right side of the base 1.

[0015] The working principle and use process of the utility model are as follows: when using, the user electrically connects the power cord 12 to the external 200V standard power supply, then injects the configured sample to be tested into the automatic dripping sample pipette 7, and sequentially places a group of ten chicken embryo chorioallantoic sacs that have been opened and membrane-removed in the groove 6 for fixing, turns on the switch button 9 to start the analysis device, and makes the small compression pump 8 provide power for the automatic dripping sample pipette 7, and controls the power to be consistent each time so that the dripping sample volume is consistent, and presses the start button 10 to start the automatic dripping sample pipette 7. Dynamically drip sample pipette 7 starts, after automatic drip sample pipette 7 adds sample dropwise to the chicken embryo chorioallantoic membrane of groove 6 inside directly below, stepping motor 4 starts automatically, and drives rotating chassis 5 to rotate 36 °, the chicken embryo chorioallantoic membrane of next groove 6 inside is moved to and drips sample directly below automatic drip sample pipette 7, until ten chicken embryo chorioallantoic membranes all finish dripping and just controllable pause button 11 is pressed, stepping motor 4 and automatic drip sample pipette 7 are suspended, just can cover preservative film constant temperature cultivation.

[0016] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0017] Although the embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A cosmetic eye irritation detection and analysis device, comprising a base (1), characterized in that: The right side of the top of the base (1) is fixedly connected to the analysis device body (2), the surface of the base (1) is provided with a motor slot (3), the bottom wall of the motor slot (3) is fixedly connected to a stepping motor (4), the output end of the stepping motor (4) is fixedly connected to a rotating chassis (5), the rotating chassis (5) is located at the top of the base (1), the surface of the rotating chassis (5) is provided with ten grooves (6), the grooves (6) are in a circular array, an automatic drop sample pipette (7) is provided on the right side of the top of the base (1), a small compression pump (8) is provided on the right side of the top of the base (1), the small compression pump (8) is located at the rear side of the automatic drop sample pipette (7), the output end of the small compression pump (8) is connected to the automatic drop sample pipette (7), a switch button (9) is provided on the left side of the base (1), a start button (10) and a pause button (11) are respectively provided on the right side of the base (1), and a power line (12) is electrically connected to the right side of the base (1).

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