Cell DNA ploidy analysis scanning platform

By designing a cell DNA ploidy analysis scanning platform, using horizontal and vertical adjustment components and image acquisition cameras to automatically adjust the focus, the problem of repeated focus modulation in the existing technology is solved, the scanning efficiency is improved, the structure is simplified, and the maintenance cost is reduced.

CN223377550UActive Publication Date: 2025-09-23SHANDONG YIZE TIANTAI MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202422806789.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-18
Publication Date
2025-09-23
Estimated Expiration
2034-11-18

AI Technical Summary

Technical Problem

Existing cell DNA image scanning microscopes need to repeatedly adjust the focal length when performing cell ploidy analysis, resulting in heavy workload, low efficiency and high maintenance costs. The existing microscope scanning platform has a complex structure.

Method used

A cell DNA ploidy analysis scanning platform was designed, which uses lateral and longitudinal adjustment components, combined with an image acquisition camera and an analysis computer. The support rod abuts against the slide to automatically adjust the focus, avoiding repeated focus modulation.

Benefits of technology

This eliminates the need to repeatedly adjust the focal length, improves scanning efficiency, simplifies the structure, and reduces maintenance costs.

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Abstract

The utility model belongs to the technical field of cell analysis, in particular to a cell DNA ploidy analysis scanning platform, which comprises an acquisition system and an analysis system, the acquisition system comprises a fixed seat arranged on the platform, the fixed seat is provided with a transverse adjusting assembly and a longitudinal adjusting assembly, the transverse adjusting assembly is provided with an elastic pressing sheet, and the longitudinal adjusting assembly is provided with a longitudinal pressing sheet. An observation assembly is inserted into the top of the fixed seat; the analysis system comprises an image acquisition camera arranged at the bottom of the observation assembly and an analysis computer electrically connected with the image acquisition camera, and the observation assembly abuts against the top of the transverse adjusting assembly through a supporting rod. According to the utility model, the observation assembly and the image acquisition camera are abutted against the transverse adjusting assembly provided with a plurality of groups of glass slides through the supporting rods, and the acquisition height can be appropriately adjusted according to different glass slides in actual use, so that the focal length is prevented from being repeatedly modulated; meanwhile, the transverse adjusting assembly and the longitudinal adjusting assembly are simple in structure and convenient to operate and maintain.
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Description

Technical Field

[0001] The utility model belongs to the technical field of cell analysis, and in particular relates to a cell DNA ploidy analysis scanning platform. Background Art

[0002] In the field of cell DNA image scanning technology, when a scanning microscope scans DNA images, cell ploidy analysis requires focusing and scanning cell images at different positions each time. Each imaging process requires modulating the focal length. For a large number of image acquisition needs, a large workload and repetitive processes are required, which greatly prolongs the working time and reduces efficiency. In addition, the existing microscopic scanning platform has a complex driving mechanism structure and high maintenance and repair costs, which needs to be improved to meet the needs of cell DNA image scanning technology.

[0003] To solve the above problems, this application proposes a cell DNA ploidy analysis scanning platform. Utility Model Content

[0004] In order to solve the problems raised in the above background technology, the utility model provides a cell DNA ploidy analysis scanning platform, which has the characteristics of simple structure and no need to repeatedly adjust the focal length.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a cell DNA ploidy analysis scanning platform, comprising an acquisition system and an analysis system, the acquisition system comprising a fixed seat arranged on the platform, the fixed seat being provided with a lateral adjustment component and a longitudinal adjustment component that cooperate with each other, the lateral adjustment component being provided with an elastic pressing sheet, and an observation component being inserted into the top of the fixed seat; the analysis system comprising an image acquisition camera arranged at the bottom of the observation component and an analysis computer electrically connected to the image acquisition camera, and the observation component is abutted against the top of the lateral adjustment component through a support rod.

[0006] As a preferred cell DNA ploidy analysis scanning platform of the present invention, the analysis computer is internally provided with a scanning imaging module and a database electrically connected to the image acquisition camera.

[0007] As a preferred cell DNA ploidy analysis scanning platform of the present invention, the lateral adjustment component includes a lateral support plate, one end of the lateral support plate is rotatably provided with a lateral adjustment screw, and the top of the lateral support plate is provided with the elastic pressing plate.

[0008] As a preferred cell DNA ploidy analysis scanning platform of the present invention, the longitudinal adjustment component includes a longitudinal support plate that is laterally slidably arranged at the bottom of the transverse support plate and a mounting seat fixed on the fixed seat, one side of the longitudinal support plate is screwed with the transverse adjustment screw, and the fixed seat is screwed with a longitudinal adjustment screw that is rotatably connected to the front of the longitudinal support plate, and the longitudinal support plate is longitudinally slidably connected to the fixed seat.

[0009] As a preferred cell DNA ploidy analysis scanning platform of the present invention, the observation component includes an imaging tube vertically inserted into the top of the fixing base, the top and bottom of the imaging tube are respectively provided with an eyepiece and an objective lens, and the image acquisition camera is screwed onto the imaging tube.

[0010] As a preferred embodiment of the cell DNA ploidy analysis scanning platform of the present invention, the support rod is fixed in the middle of the imaging tube, and a ball is rotatably provided at the bottom of the support rod to abut against the transverse support plate.

[0011] Compared with the prior art, the beneficial effects of the present invention are as follows: the observation assembly and the image acquisition camera in the present invention are connected to the transverse adjustment assembly equipped with multiple groups of slides through the support rod. In actual use, the acquisition height can be adjusted according to the suitability of different slides, thereby avoiding repeated adjustment of the focal length; at the same time, the transverse and longitudinal adjustment assemblies of the present invention have a simple structure, are easy to operate and easy to maintain. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0013] Figure 1 This is an axonometric drawing of the present utility model;

[0014] Figure 2 It is a top view of the utility model;

[0015] Figure 3 It is a cross-sectional view of the utility model;

[0016] Figure 4 It is a structural schematic diagram of the transverse adjustment component and the longitudinal adjustment component in the present utility model.

[0017] In the figure: 1. Fixed seat; 2. Lateral adjustment assembly; 201. Lateral support plate; 202. Lateral adjustment screw; 3. Longitudinal adjustment assembly; 301. Longitudinal support plate; 302. Mounting seat; 303. Longitudinal adjustment screw; 4. Elastic pressure piece; 5. Observation assembly; 501. Imaging tube; 502. Eyepiece; 503. Objective lens; 6. Image acquisition camera; 7. Analysis computer; 8. Support rod; 9. Ball bearing. DETAILED DESCRIPTION

[0018] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0019] Example 1: Figure 1 and Figure 2 As shown;

[0020] A cell DNA ploidy analysis scanning platform includes an acquisition system and an analysis system. The acquisition system includes a fixed base 1 arranged on the platform, and the fixed base 1 is provided with a lateral adjustment component 2 and a longitudinal adjustment component 3 that cooperate with each other. The lateral adjustment component 2 is provided with an elastic pressing piece 4, and an observation component 5 is inserted into the top of the fixed base 1; the analysis system includes an image acquisition camera 6 arranged at the bottom of the observation component 5 and an analysis computer 7 electrically connected to the image acquisition camera 6, and the observation component 5 is abutted against the top of the lateral adjustment component 2 through a support rod 8. The analysis computer 7 is internally provided with a scanning imaging module and a database electrically connected to the image acquisition camera 6.

[0021] It should be noted that: in this embodiment, the slide is photographed and recorded by the image acquisition camera 6, and the data is stored in the database of the analysis computer 7. The analysis computer 7 completes the scanning of all images based on the acquired parameters and calculated data.

[0022] It should be noted that: in this embodiment, the elastic pressing pieces 4 are symmetrically arranged in multiple groups, and the glass slide spans the lateral adjustment component 2, and ensures that the glass slide can abut against the support rod 8.

[0023] In this embodiment: the observation component 5 and the image acquisition camera 6 are connected to the horizontal adjustment component 2 equipped with multiple groups of slides through the support rod 8. In actual use, the acquisition height can be adjusted according to the suitability of different slides, thereby avoiding repeated adjustment of the focal length; the horizontal and vertical adjustment components of this embodiment have simple structures, easy operation and convenient maintenance.

[0024] like Figure 3 and Figure 4As shown;

[0025] In an optional embodiment, the lateral adjustment component 2 includes a lateral support plate 201, one end of which is rotatably provided with a lateral adjustment screw 202, and the top of the lateral support plate 201 is provided with an elastic pressure plate 4, and the longitudinal adjustment component 3 includes a longitudinal support plate 301 that is laterally slidably provided at the bottom of the lateral support plate 201 and a mounting seat 302 fixed on the fixed seat 1, one side of the longitudinal support plate 301 is screwed with a lateral adjustment screw 202, and the fixed seat 1 is screwed with a longitudinal adjustment screw 303 that is rotatably connected to the front of the longitudinal support plate 301, and the longitudinal support plate 301 is longitudinally slidably connected to the fixed seat 1.

[0026] In this embodiment, rotating the transverse adjustment screw 202 can drive the transverse support plate 201 to move horizontally along the longitudinal support plate 301. Similarly, rotating the longitudinal adjustment screw 303 can drive the longitudinal support plate 301 and the transverse support plate 201 thereon to move longitudinally.

[0027] In an optional embodiment, the observation assembly 5 includes an imaging tube 501 vertically inserted into the top of the fixing base 1, an eyepiece 502 and an objective lens 503 are respectively provided at the top and bottom of the imaging tube 501, and an image acquisition camera 6 is screwed onto the imaging tube 501.

[0028] In an optional embodiment, the support rod 8 is fixed in the middle of the imaging tube 501 , and a ball 9 is rotatably provided at the bottom of the support rod 8 to abut against the transverse support plate 201 .

[0029] In this embodiment, the ball 9 at the bottom of the support rod 8 rolls on the glass slide while moving and synchronously raises and lowers the height of the objective lens 503 and the image acquisition camera 6 in real time according to different positions and the glass slide, thereby avoiding repeated adjustment of the focal length.

[0030] It should be noted that the support rod 8 is fixed to the imaging tube 501 by a top screw. In actual use, the height of the horizontal support plate 201 on the imaging tube 501 can be adaptively adjusted according to the magnification of the objective lens 503. The support rod 8 uses the gravity of the imaging tube 501 itself to achieve lifting and lowering. At the same time, whether to use the support rod 8 can be selected according to actual needs.

[0031] The working principle and usage process of the present invention are as follows: the image acquisition camera 6 is used to take pictures and record the glass slides, and the data is stored in the database. The analysis computer 7 completes the scanning of all images based on the acquired parameters and calculated data (the working principle of the analysis computer 7 and the image acquisition camera 6 is the existing technology and will not be explained in detail here); when it is necessary to adjust the horizontal position of the glass slide or observe other glass slides, it is only necessary to rotate the horizontal adjustment screw 202 to drive the horizontal support plate 201 to move horizontally along the longitudinal support plate 301. Similarly, rotating the longitudinal adjustment screw 303 can drive the longitudinal support plate 301 and the horizontal support plate 201 thereon to move longitudinally; while moving, the ball 9 at the bottom of the support rod 8 rolls on the glass slide and synchronously raises and lowers the height of the objective lens 503 and the image acquisition camera 6 according to different positions and glass slides in real time, thereby avoiding repeated adjustment of the focal length.

[0032] Finally, it should be noted that the above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art will be able to modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein with equivalents. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.

Claims

1. A cell DNA ploidy analysis scanning platform, comprising an acquisition system and an analysis system, characterized in that: The collection system comprises a fixed seat (1) arranged on the platform, the fixed seat (1) is provided with a lateral adjustment component (2) and a longitudinal adjustment component (3) that cooperate with each other, the lateral adjustment component (2) is provided with an elastic pressing piece (4), and an observation component (5) is inserted into the top of the fixed seat (1); The analysis system includes an image acquisition camera (6) arranged at the bottom of the observation component (5) and an analysis computer (7) electrically connected to the image acquisition camera (6), and the observation component (5) is abutted against the top of the lateral adjustment component (2) through a support rod (8).

2. The cell DNA ploidy analysis scanning platform according to claim 1, characterized in that: The analysis computer (7) is internally provided with a scanning imaging module and a database electrically connected to the image acquisition camera (6).

3. The cell DNA ploidy analysis scanning platform according to claim 2, characterized in that: The transverse adjustment assembly (2) comprises a transverse support plate (201), one end of the transverse support plate (201) is rotatably provided with a transverse adjustment screw (202), and the top of the transverse support plate (201) is provided with the elastic pressing piece (4).

4. The cell DNA ploidy analysis scanning platform according to claim 3, characterized in that: The longitudinal adjustment assembly (3) comprises a longitudinal support plate (301) which is laterally slidably arranged at the bottom of the transverse support plate (201) and a mounting seat (302) which is fixed on the fixing seat (1); the transverse adjustment screw (202) is screwed onto one side of the longitudinal support plate (301); a longitudinal adjustment screw (303) which is rotatably connected to the front of the longitudinal support plate (301) is screwed onto the fixing seat (1); and the longitudinal support plate (301) is longitudinally slidably connected to the fixing seat (1).

5. The cell DNA ploidy analysis scanning platform according to claim 4, characterized in that: The observation assembly (5) comprises an imaging tube (501) vertically inserted into the top of the fixing seat (1), an eyepiece (502) and an objective lens (503) are provided at the top and bottom of the imaging tube (501), respectively, and the image acquisition camera (6) is screwed onto the imaging tube (501).

6. The cell DNA ploidy analysis scanning platform according to claim 5, characterized in that: The support rod (8) is fixed in the middle of the imaging tube (501), and a ball (9) is rotatably provided at the bottom of the support rod (8) and abuts against the transverse support plate (201).