Mouse experimental behavior box

Abstract

The utility model discloses a mouse experimental behavior box, including insulation box, water supply subassembly and smell transmission subassembly, the upper surface of insulation box is provided with storage battery, one side outer wall of insulation box is sealed and inserted with two insulation tube, the one end of insulation tube inner surface is sealed and clamped with trapezoidal block, and the one end of insulation tube is sealed and sleeved with sealing cover, and the sealing cover is sealed and sleeved with the sealing cover. Outer connecting wires are inserted into the upper surfaces of the two insulating pipes in a sealed and penetrating mode, two lamp beads are fixedly connected to the outer wall of one side of the insulating box, and the outer connecting wires and the lamp beads are connected in series. Through the design of combining the external connecting line, the double-strand telescopic line and the lamp bead, a closed circuit is formed when a mouse licks water, the voltage of the lamp bead is measured by the electronic multimeter, and the lighting times of the lamp bead are recorded, so that whether the mouse licks water or not can be monitored, and the accuracy of a water licking experiment in a behavior box of the mouse can be ensured through the mode.

Description

Technical Field

[0001] The utility model relates to the technical field of mouse experimental behavior boxes, in particular to a mouse experimental behavior box. Background Art

[0002] Currently, experimenters will automatically control and record the training of mice's olfactory conditioned reflex learning and make behavioral analysis. The entire model will place mice in a behavioral box and train them to detect or distinguish odor stimulation through licking experiments to form conditioned reflexes, thereby analyzing their perception and identification ability of odors. This model can provide behavioral data for studying the neural mechanisms of mice's detection, discrimination, learning and memory of odors, and is also a powerful tool for evaluating new drugs for the treatment of neurological diseases.

[0003] However, during the use of existing behavior boxes, since it can only determine whether the mouse licks water by infrared or position prediction, there is doubt as to whether the mouse's tongue licks water, resulting in inaccurate experimental data. Therefore, in order to advance the industry's technology, better ensure the accuracy of the mouse licking water experiment in the behavior box, and improve the competitiveness of core technologies, this application proposes a new implementation plan that is different from the existing behavior box experimental structure and usage method. Utility Model Content

[0004] The utility model aims to solve the problem that when using the existing behavior box, it is doubtful whether the mouse licks water with its tongue, which leads to inaccurate experimental data, and proposes a mouse experimental behavior box.

[0005] In order to achieve the above purpose, the present invention adopts the following technical solutions:

[0006] A mouse experimental behavior box comprises an insulating box, a water supply component and an odor transmission component. A battery is provided on the upper surface of the insulating box. Two insulating tubes are sealed and plugged into the outer wall of one side of the insulating box. A trapezoidal block is sealed and clamped at one end of the inner surface of the insulating tube, and a sealing cover is provided on one end of the insulating tube. External connecting wires are respectively sealed and plugged through the upper surfaces of the two insulating tubes. Two lamp beads are fixedly connected to the outer wall of one side of the insulating box. The external connecting wires and the lamp beads are connected in series. One end of the external connecting wire is connected to one electrode of the battery. A double-strand telescopic wire is fixedly plugged into the top inner wall of the insulating box. One end of the double-strand telescopic wire is connected to the other electrode of the battery. An electronic multimeter is provided on the upper surface of the insulating box. The electronic multimeter is electrically connected to the lamp beads. A connecting belt is provided on the bottom end of the outer surface of the double-strand telescopic wire.

[0007] Furthermore, the water supply assembly includes a water tank, an insulating box fixedly connected to the top of the water tank, a base fixedly connected to the bottom of the water tank, two pump bodies fixedly connected to the upper surface of the base, the water inlet ends of the two pump bodies are connected to the water tank through water pipes, and the water outlet ends of the two pump bodies are respectively connected to the water inlet ends of the corresponding insulating pipes through water pipes.

[0008] Furthermore, the odor delivery component includes a gas tank, which is placed on the upper surface of the base. The two output ends of the gas tank are respectively fixed with solenoid valves, and the other ends of the two solenoid valves are respectively sealed and plugged with connecting pipes, and the other ends of the two connecting pipes are respectively sealed and plugged into the air inlets of the corresponding insulating tubes.

[0009] Furthermore, the outer surfaces of the two insulating tubes are respectively sealed and clamped with curved transparent covers.

[0010] Furthermore, a transparent plate is sealed and clamped on one side outer wall of the insulation box.

[0011] Furthermore, a top cover is rotatably connected to the top of the insulation box.

[0012] Furthermore, an air filter assembly is provided at the bottom of the top cover, and the air filter assembly includes a connecting tube, which is fixedly inserted into the bottom of the top cover, an activated carbon air permeable plate is provided on the inner surface of the connecting tube, and a dustproof net is clamped on the top of the connecting tube.

[0013] Furthermore, a hollow plate and a limiting ring are clamped on the inner surface of the connecting tube, and the hollow plate and the limiting ring are respectively located at the bottom and top of the activated carbon breathable plate.

[0014] The beneficial effects of the utility model are:

[0015] 1. Through the design of combining external connecting wires, double-strand telescopic wires and lamp beads, electricity can be supplied to the water in the insulating tube through the external connecting wires. After the mouse licks the water, the current in the water connects the circuit of the lamp bead. The voltage of the lamp bead is measured by the electronic multimeter, and the lighting status and number of times the lamp bead is on are recorded. In this way, whether the mouse licks the water can be monitored. This method is different from the infrared or position prediction method in the existing technology to detect the mouse licking status, and can ensure the accuracy of the mouse licking experiment in the behavior box.

[0016] 2. The curved transparent cover allows operators to observe the water level of the water supply assembly when injecting water into the insulating tube to prevent water from overflowing. The transparent panel on the side of the insulating box allows operators to directly observe the behavior of mice licking water in the insulating box. It also facilitates cleaning of the interior of the insulating box.

[0017] 3. Through the design of the air filtration component, operators can filter the air entering the insulation box from the laboratory, thereby reducing the impact of external factors on the mouse water licking experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the left side three-dimensional structure of a mouse experimental behavior box proposed in the present invention;

[0019] Figure 2 This is a partial cross-sectional structural diagram of a mouse experimental behavior box proposed in the present invention;

[0020] Figure 3 This is a side cross-sectional structural diagram of a mouse experimental behavior box proposed in the present invention;

[0021] Figure 4 This is a schematic diagram of the right side three-dimensional structure of a mouse experimental behavior box proposed in the present invention.

[0022] In the figure: 1. Insulation box; 2. Water supply assembly; 201. Water tank; 203. Pump body; 3. Insulation tube; 4. Trapezoidal block; 5. Sealing cover; 6. External connecting wire; 7. Battery; 8. Lamp bead; 9. Electronic multimeter; 10. Double-strand telescopic wire; 11. Connecting belt; 12. Odor transmission assembly; 1201. Gas tank; 1202. Solenoid valve; 1203. Connecting pipe; 13. Base; 14. Curved transparent cover; 15. Transparent plate; 16. Top cover; 17. Air filter assembly; 1701. Connecting tube; 1702. Activated carbon breathable plate; 1703. Dustproof net; 1704. Hollow plate. DETAILED DESCRIPTION

[0023] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0024] Reference Figure 1-Figure 4 A mouse experimental behavior box includes an insulating box 1, a water supply component 2, and an odor delivery component 12. A battery 7 is provided on the upper surface of the insulating box 1. In this solution, the voltage of the battery 7 is controlled below 5V, and the current generated by the power supply is controlled below 0.1mA to prevent danger to the mice;

[0025] Two insulating tubes 3 are sealed and inserted into the outer wall of one side of the insulating box 1. A sealing cover 5 is sealed on the outward end of the insulating tube 3. A trapezoidal block 4 is sealed and clamped on one end of the inner surface of the inward end of the insulating tube 3. External connecting wires 6 are sealed and inserted through the upper surfaces of the two insulating tubes 3. The conductive ends of the external connecting wires 6 are located vertically downward in the insulating tube 3 and touch the inner wall of the insulating tube 3.

[0026] Two lamp beads 8 are bonded to the outer wall of one side of the insulating box 1. The external connecting wire 6 and the lamp beads 8 are connected in series. The lamp beads 8 are low-power lamp beads with a power between 0.06 watts and 0.2 watts, and are used as indicator lights. One end of the external connecting wire 6 is connected to one electrode of the battery 7. A double-strand telescopic wire 10 is fixedly plugged into the top inner wall of the insulating box 1. One end of the double-strand telescopic wire 10 is connected to the other electrode of the battery 7. The other end of the double-strand telescopic wire 10 is provided with a connecting belt 11 on the outer surface. The connecting belt 11 can be tied to the mouse so that the core of the bottom end of the double-strand telescopic wire 10 contacts the mouse skin.

[0027] An electronic multimeter 9 is fixed on the upper surface of the insulating box 1. The electronic multimeter 9 can be connected in parallel to both ends of the lamp bead 8 and used as a voltmeter to detect and record whether there is current passing and voltage generated;

[0028] By combining the external connecting wire 6, the lamp bead 8, the battery 7, the double-strand retractable wire 10 and the mouse itself, a closed circuit can be formed when the mouse licks water. At this time, the current in the water connects the circuit of the lamp bead 8. The electronic multimeter 9 measures the voltage of the lamp bead 8 and records whether the lamp bead 8 generates voltage and the number of times it lights up, thereby monitoring whether the mouse licks water.

[0029] This method is different from the infrared or position prediction method in the existing technology to detect the mouse licking water status, and can ensure the accuracy of the mouse licking water experiment in the behavior box.

[0030] Among them, the water supply component 2 includes a water tank 201, the insulating box 1 is bonded to the top of the water tank 201, the bottom of the insulating box 1 is bonded with a base 13, and the upper surface of the base 13 is fixed with two pump bodies 203 by bolts. The input ends of the two pump bodies 203 are connected to the water tank 201 through water pipes, and the output ends of the two pump bodies 203 are respectively connected to the water inlet ends of the corresponding insulating tubes 3 through water pipes. The water supply component 2 is used to inject water into the insulating tube 3.

[0031] The odor transmission component 12 includes a gas tank 1201, which is placed on the upper surface of the base 13. The two output ends of the gas tank 1201 are respectively fixed with solenoid valves 1202, and the other ends of the two solenoid valves 1202 are respectively sealed and plugged with connecting pipes 1203, and the other ends of the two connecting pipes 1203 are respectively sealed and plugged into the air inlets of the corresponding insulating tubes 3. The odor transmission component 12 is used to input and transmit odor into the insulating tube 3.

[0032] At the same time, the outer surfaces of the two insulating tubes 3 are respectively sealed and connected with arc-surface transparent covers 14. Through the design of the arc-surface transparent covers 14, the operator can timely observe the water level of water injected into the insulating tube 3 by the water supply component 2 to avoid overflow of water in the insulating tube 3. The outer wall of one side of the insulating box 1 is sealed and connected with a transparent plate 15. The design of the transparent plate 15 on the side of the insulating box 1 facilitates the operator to directly observe the experimental behavior of mice licking water in the insulating box 1, and at the same time, it also facilitates the operator to clean the inside of the insulating box 1.

[0033] The top of the insulating box 1 is also rotatably connected to a top cover 16, and an air filter assembly 17 is provided at the bottom of the top cover 16. The air filter assembly 17 includes a connecting tube 1701, which is fixedly inserted into the bottom of the top cover 16. The inner surface of the connecting tube 1701 is provided with an activated carbon air permeable plate 1702, and a dustproof net 1703 is clamped on the top of the connecting tube 1701. The inner surface of the connecting tube 1701 is clamped with a hollow plate 1704 and a limiting ring, and the hollow plate 1704 and the limiting ring are respectively located at the bottom and top of the activated carbon air permeable plate 1702. Through the design of the air filter assembly 17, the operator can filter the air entering the insulating box 1 from the laboratory, thereby reducing the impact of external factors on the mouse licking water experiment.

[0034] The working principle of this embodiment is as follows: when in use, the operator first opens the top cover 16, then ties the connecting belt 11 to the mouse, and makes the core of the bottom end of the double-strand telescopic wire 10 contact the mouse's skin, and then closes the top cover 16. At this time, the operator can observe the water level through the arc-surface transparent cover 14, operate the water supply component 2 to inject water into one of the insulating tubes 3, and the liquid level in the insulating tube 3 does not exceed the height of the trapezoidal block 4. At this time, the operator selects a suitable battery 7 to connect to the circuit, and the external connecting wire 6 and the double-strand telescopic wire 10 are both energized. The external connecting wire 6 transmits a weak current to the water in the insulating tube 3. Subsequently, the operator operates the solenoid valve 1202 on the corresponding insulating tube 3. At this time, the gas tank 12 The sweet gas in 01 enters the insulating tube 3 through the connecting tube 1203, and finally enters the insulating box 1. At this time, the mouse will reach the trapezoidal block 4 of the insulating tube 3 when it smells the odor. The trapezoidal block 4 can limit the mouse's head. In this way, the mouse can only extend its tongue into the insulating tube 3. If the tongue touches the water in the insulating tube 3, the current in the water will be transmitted to the mouse. At this time, the circuit of the lamp bead 8 is connected, the lamp bead 8 lights up, and the electronic multimeter 9 measures the voltage of the lamp bead 8, and records the voltage and the number of times the lamp bead 8 lights up, so as to monitor whether the mouse licks water; similarly, the operator can repeat the operation on another insulating tube 3, so that the mouse is licking water in the behavior box.

[0035] The above is only a preferred specific implementation method of the present invention, but the protection scope of the present invention is not limited to this. Any technician familiar with the technical field within the technical scope disclosed by the present invention can make equivalent replacements or changes based on the technical solution and utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A mouse experimental behavior box, comprising an insulating box (1), a water supply component (2) and an odor transmission component (12), wherein a battery (7) is provided on the upper surface of the insulating box (1), characterized in that: Two insulating tubes (3) are sealed and plugged into the outer wall of one side of the insulating box (1), one end of the inner surface of the insulating tube (3) is sealed and clamped with a trapezoidal block (4), and one end of the insulating tube (3) is sealed and sleeved with a sealing cover (5). External connecting wires (6) are respectively sealed and inserted through the upper surfaces of the two insulating tubes (3). Two lamp beads (8) are fixedly connected to the outer wall of one side of the insulating box (1), the external connecting wires (6) and the lamp beads (8) are connected in series, and one end of the external connecting wire (6) is connected to one electrode of the battery (7). A double-strand telescopic wire (10) is fixedly plugged into the top inner wall of the insulating box (1), and one end of the double-strand telescopic wire (10) is connected to the other electrode of the battery (7). An electronic multimeter (9) is provided on the upper surface of the insulating box (1), and the electronic multimeter (9) is electrically connected to the lamp beads (8). A connecting belt (11) is sleeved on the bottom end of the outer surface of the double-strand telescopic wire (10).

2. A mouse experimental behavior box according to claim 1, characterized in that The water supply assembly (2) comprises a water tank (201), an insulating box (1) fixedly connected above the water tank (201), a base (13) fixedly connected to the bottom of the water tank (201), two pump bodies (203) fixedly connected to the upper surface of the base (13), the water inlet ends of the two pump bodies (203) being connected to the water tank (201) via water pipes, and the water outlet ends of the two pump bodies (203) being connected to the water inlet ends of corresponding insulating pipes (3) via water pipes.

3. A mouse experimental behavior box according to claim 1, characterized in that The odor delivery component (12) includes a gas tank (1201), which is placed on the upper surface of the base (13). The two output ends of the gas tank (1201) are respectively fixedly provided with solenoid valves (1202), and the other ends of the two solenoid valves (1202) are respectively sealed and plugged with connecting pipes (1203), and the other ends of the two connecting pipes (1203) are respectively sealed and plugged into the air inlets of the corresponding insulating tubes (3).

4. A mouse experimental behavior box according to claim 1, characterized in that, The outer surfaces of the two insulating tubes (3) are respectively sealed and clamped with curved transparent covers (14).

5. A mouse experimental behavior box according to claim 1, characterized in that, A transparent plate (15) is sealed and clamped on one side outer wall of the insulation box (1).

6. A mouse experimental behavior box according to claim 5, characterized in that, The top of the insulation box (1) is rotatably connected to a top cover (16).

7. A mouse experimental behavior box according to claim 6, characterized in that: An air filter assembly (17) is provided at the bottom of the top cover (16), and the air filter assembly (17) includes a connecting tube (1701). The connecting tube (1701) is fixedly inserted into the bottom of the top cover (16), and an activated carbon air permeable plate (1702) is provided on the inner surface of the connecting tube (1701), and a dustproof net (1703) is clamped on the top of the connecting tube (1701).

8. A mouse experimental behavior box according to claim 7, characterized in that: The inner surface of the connecting tube (1701) is clamped with a hollow plate (1704) and a limiting ring, and the hollow plate (1704) and the limiting ring are respectively located at the bottom and top of the activated carbon breathable plate (1702).

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