Multifunctional perfusion needle for animal experiments

Abstract

The utility model relates to a multifunctional perfusion needle for animal experiments. The multifunctional perfusion needle comprises a needle head, a needle head tube body and a connector which are connected in sequence, the needle head tube body buckle is sleeved on one side, close to the needle head, of the needle head tube body; the wrapping pipe is arranged on the needle head pipe body in a sleeving mode and comprises a first wrapping pipe section, an expansion pipe section and a second wrapping pipe section which are sequentially connected, the second wrapping pipe section abuts against the connector, and a buckle area matched with a buckle of the needle head pipe body is arranged on the inner side of the first wrapping pipe section. A fixing part used for fixing the relative position of the wrapping tube and the needle tube body is arranged on the side wall of the second wrapping tube section. Compared with the prior art, the needle can retract and keep the position fixed after puncturing into ventricles and veins, has the function of preventing tissues and organs from being punctured, and is not easy to fall off; the fixing part with the wrapping tube is adopted, so that fixation of the perfusion needle in the needle inserting process of the perfusion needle is further improved; the failure rate of an animal perfusion experiment is greatly reduced, and the experiment efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of perfusion needles, in particular to a multifunctional perfusion needle for animal experiments. Background Art

[0002] Animal experiments are the foundation and important supporting conditions for life science research. Almost all scientific research, teaching, production, testing, safety evaluation and achievement assessment in the field of life sciences cannot be separated from animal experiments. The exploration and understanding of animal experiments have formed basic life science theories such as zoology, anatomy, and physiology. And thanks to animal experiments, the theoretical systems of modern medicine such as immunology, microbiology, infectious diseases, and virology have gradually been formed. In basic life science theories, anatomy is of vital importance. During the dissection process of animal experiments, different fluids are usually used to perfuse the organs of animal models to maintain the integrity of various organs and to isolate various primary cells.

[0003] Taking the mouse model as an example, perfusion experiments commonly performed in mice include cardiac perfusion and vena portal vein perfusion. In cardiac perfusion experiments, the mouse is first anesthetized, the rib cage is opened, and the heart is exposed. Next, a perfusion needle is inserted into the left ventricle of the heart, and the right atrial appendage is ruptured. Physiological saline and tissue fixative are then perfused using a syringe or peristaltic pump. Accurate insertion of the perfusion needle into the heart is crucial during this experiment. Shallow insertion can easily cause the needle to slip out, while deeper insertion can result in the needle perforating the heart. Furthermore, proper needle fixation is crucial for a successful perfusion experiment. Firm fixation can easily cause the needle to puncture the heart during perfusion convulsions, while loose fixation can easily cause the needle to slip out. In vena portal vein perfusion experiments, the mouse is anesthetized, the abdominal cavity is opened, and the intestinal tissue is pushed aside to expose the inferior vena cava. The perfusion needle is then inserted, and the portal vein is ruptured. Physiological saline and collagenase are then perfused and digested using a syringe or peristaltic pump. During this experiment, inserting the perfusion needle into the inferior vena cava and maintaining its stability are also key to the success of the experiment. This type of experiment requires practice on a large number of animals, which is time-consuming and costly.

[0004] Currently, in perfusion experiments on mice, researchers often use injection needles, infusion needles, or conventional indwelling cannulas. This leads to numerous drawbacks during the experiment, including the following common issues: 1. The sharp tips of perfusion needles for the heart or blood vessels can easily pierce the blood vessels or heart during fixation or during perfusion. 2. During cardiac perfusion, assistance with needle fixation or tape is often required, but this can often lead to the needle slipping due to unstable grip or the mouse's trembling during perfusion. 3. During liver perfusion, indwelling cannulas in the inferior vena cava or portal vein often require surgical suture ligation, which can easily cause the cannula to fall off. Utility Model Content

[0005] The purpose of the present invention is to provide a multifunctional perfusion needle for animal experiments, particularly suitable for animal vascular / cardiac perfusion experiments, in order to overcome at least one of the aforementioned drawbacks of the prior art. Specifically, the present invention addresses the drawbacks of perfusion technology in animal experiments, and aims to solve the problem of perfusion failure caused by needle disengagement or over-insertion. The multifunctional perfusion needle comprises a needle body, a covering tube, a snap-on area, an expansion area, and a fixing portion. During cardiac perfusion experiments, the needle tip is concealed by pulling the needle body, preventing cardiac damage caused by needle movement. The expansion area expands during the pulling process, preventing the needle from dislodging after insertion into the ventricle and preventing it from slipping or damaging the heart. During hepatic venous perfusion, the needle tip is concealed by pulling the needle body, preventing cardiac damage caused by needle movement. The fixing portion allows for flexible control of the size of the expansion area, thereby filling the venous vessels, preventing needle slippage, facilitating surgical suture ligation, and preventing bubbles from being generated during manual fluid changes during perfusion. The multifunctional perfusion needle can significantly reduce the failure rate of animal perfusion experiments, while significantly reducing personnel time, improving experimental efficiency, and effectively solving the defects brought about by existing technologies.

[0006] The purpose of the utility model can be achieved through the following technical solutions:

[0007] A multifunctional perfusion needle for animal experiments, comprising:

[0008] The needle, needle body and connector are connected in sequence;

[0009] a needle tube buckle sleeved on the needle tube side near the needle; and

[0010] The covering tube is sleeved on the needle tube body, and includes a first covering tube section, an expansion tube section and a second covering tube section connected in sequence. The second covering tube section is abutted against the connecting head. The inner side of the first covering tube section is provided with a snap-fit ​​area that cooperates with the snap-fit ​​of the needle tube body. The side wall of the second covering tube section is provided with a fixing part for fixing the relative position of the covering tube and the needle tube body.

[0011] Furthermore, the needle tube body buckle is an annular protrusion structure, and a first spiral structure is provided on its outer surface.

[0012] Furthermore, the snap-lock region is a second spiral structure disposed on the inner side of the first sheathing section and cooperating with the first spiral structure. When the needle tube body rotates back into the first sheathing section, the snap-lock region of the needle tube body locks. When the needle tube body rotates in the opposite direction and extends out of the first sheathing section, the snap-lock region of the needle tube body unlocks. When the needle tube body rotates back into the first sheathing section, the needle can be hidden within the first sheathing section.

[0013] Furthermore, the expansion pipe section is an elastic pipe section, which extends outward in the circumferential direction after compression to form a bulge. Preferably, the expansion pipe section is an elastic pipe section made of a weak elastic material.

[0014] Furthermore, the first cladding pipe section and the second cladding pipe section are rigid pipe sections, preferably rigid pipe sections made of hard plastic or stainless steel.

[0015] Furthermore, the fixing part is a bolt extrusion fixing part, which includes a screw threadedly connected to the side wall of the second covering tube segment, and a rotating head arranged at the outer end of the screw at the second covering tube segment. By rotating the rotating head, the screw is brought into contact with the needle tube body, thereby fixing the relative positions of the covering tube and the needle tube body.

[0016] Furthermore, the fixing part is a pressing and locking fixing part, which includes a pressing rod passing through the side wall of the second covering tube segment, and a pressing head arranged at the outer end of the pressing rod at the second covering tube segment. By pressing the pressing head, the pressing rod is brought into contact with the needle tube body, thereby fixing the relative positions of the covering tube and the needle tube body.

[0017] Furthermore, the needle tip of the needle is a beveled needle tip.

[0018] Furthermore, the outer diameter of the needle tube body is consistent with the inner diameter of the covering tube.

[0019] Furthermore, the connector is a standard Luer connector made of medical plastic or medical stainless steel, and is used to connect an ordinary syringe or infusion tube.

[0020] Compared with the existing technology, the multifunctional perfusion needle provided by the utility model adopts an anti-dropout fixed perfusion needle equipped with a needle head and a tube body, a covering tube, an expansion area, a fixing part, and a connecting seat. After piercing the ventricle and vein, the needle head retracts and maintains a fixed position, has the function of preventing tissues and organs from being punctured and is not easy to fall out; the use of a fixing part with a covering tube further improves the fixation of the perfusion needle during the insertion process of the perfusion needle; greatly reduces the failure rate of animal perfusion experiments and improves the experimental efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a front view of the multifunctional perfusion needle for animal experiments in the embodiment;

[0022] Figure 2 This is a side view of the multifunctional perfusion needle for animal experiments in the embodiment;

[0023] The numbers in the figure are as follows: 1-needle tube body; 2-covering tube; 21-first covering tube section; 22-expansion tube section; 23-second covering tube section; 3-needle tube body buckle; 4-buckle area; 5-fixing part; 6-connector. DETAILED DESCRIPTION

[0024] The present invention is described in detail below with reference to the accompanying drawings and specific embodiments. This embodiment is implemented based on the technical solution of the present invention, and provides a detailed implementation method and specific operation process, but the protection scope of the present invention is not limited to the following embodiments.

[0025] Example

[0026] See also Figure 1-2 A multifunctional perfusion needle for animal experiments comprises: a needle, a needle body 1 and a connector 6 connected in sequence; a needle body buckle 3 sleeved on the needle body 1 near the needle tip; and a covering tube 2 sleeved on the needle body 1, which comprises a first covering tube segment 21, an expansion tube segment 22 and a second covering tube segment 23 connected in sequence, the second covering tube segment 23 abuts against the connector 6, a buckle area 4 cooperating with the needle body buckle 3 is provided on the inner side of the first covering tube segment 21, and a fixing part 5 for fixing the relative position of the covering tube 2 and the needle body 1 is provided on the side wall of the second covering tube segment 23.

[0027] In this embodiment, the outer diameter of the needle body 1 is consistent with the inner diameter of the covering tube 2; the needle tip is a beveled needle tip; the connector 6 is a standard Luer connector made of medical plastic or medical stainless steel, which is used to connect an ordinary syringe or infusion tube.

[0028] Please refer to Figure 1 The needle body buckle 3 is an annular protrusion with a first spiral pattern on its outer surface. The buckle area 4 is a second spiral pattern located inside the first sheathing section 21 and cooperating with the first spiral pattern. When the needle body 1 rotates back into the first sheathing section 21, the needle body buckle 3 and the buckle area 4 lock. When the needle body 1 rotates back and extends out of the first sheathing section 21, the needle body buckle 3 and the buckle area 4 unlock. Specifically, the needle body 1 can be pulled back and rotated to conceal the needle tip, preventing it from puncturing or damaging tissue or blood vessels.

[0029] Please refer to Figure 1 The expansion tube segment 22 is an elastic tube segment, preferably made of a weakly elastic material. After compression, the elastic tube segment extends outward along the circumference to form a protrusion. The first and second covering tube segments 21, 23 are rigid tube segments made of hard plastic or stainless steel. When the needle body buckle 3 is locked with the buckle area 4, the second covering tube segment 23 is squeezed, and the expansion tube segment 22 is compressed and expands in the heart or blood vessels, preventing the perfusion needle from falling out.

[0030] Please refer to Figure 1 The fixing portion 5 is a bolt-extrusion fixing portion or a press-engage fixing portion.

[0031] When the fixing part 5 is a bolt extrusion fixing part, it includes a screw threadedly connected to the side wall of the second covering tube section 23, and a rotating head arranged at the outer end of the screw at the second covering tube section 23. By rotating the rotating head, the screw is brought into contact with the needle tube body 1, thereby fixing the relative position of the covering tube 2 and the needle tube body 1 to resist the restoring force of the expansion zone 5.

[0032] When the fixing part 5 is a pressing and locking fixing part, it includes a pressing rod passing through the side wall of the second covering tube section 23, and a pressing head arranged at the outer end of the pressing rod at the second covering tube section 23. By pressing the pressing head, the pressing rod is brought into contact with the needle tube body 1, thereby fixing the relative position of the covering tube 2 and the needle tube body 1 to resist the restoring force of the expansion area 5.

[0033] After the perfusion of the heart is completed, the fixing portion 5 is relaxed to allow the expansion area 5 to recover and be withdrawn from the heart to minimize damage to the heart. After the venous perfusion is completed, the expansion area 5 can also provide a reference position for surgical suture bandaging.

[0034] In summary, in animal perfusion experiments, this multifunctional perfusion needle maintains its position after effectively piercing the heart or blood vessels, offering a certain degree of resistance to pullout and preventing it from dislodging. The spiral structure of the covering tube conceals the needle tip while also securing its position. The fixing portion secures the covering tube and flexibly adjusts the size of the expansion zone, providing a controllable solution for perfusion conditions in different tissues. This multifunctional perfusion needle significantly reduces the failure rate of perfusion experiments and improves experimental efficiency.

[0035] The above description is merely a preferred embodiment of the present invention and does not constitute any limitation thereto. Any person skilled in the art may utilize the above disclosure to modify or remodel the present invention into equivalent embodiments. However, any simple modification, equivalent variation, or modification of the above embodiment that does not depart from the technical content of the present invention and is based on the technical essence of the present invention shall still fall within the scope of protection of the present invention.

Claims

1. A multifunctional perfusion needle for animal experiments, characterized in that: include: A needle, a needle tube (1) and a connector (6) connected in sequence; a needle tube buckle (3) sleeved on the needle tube (1) near the needle; and A covering tube (2) is sleeved on a needle tube body (1), comprising a first covering tube section (21), an expansion tube section (22) and a second covering tube section (23) connected in sequence, wherein the second covering tube section (23) abuts against a connector (6), a buckle area (4) is provided on the inner side of the first covering tube section (21) for cooperating with the buckle (3) of the needle tube body, and a fixing portion (5) is provided on the side wall of the second covering tube section (23) for fixing the relative position of the covering tube (2) and the needle tube body (1).

2. The multifunctional perfusion needle for animal experiments according to claim 1, characterized in that: The needle tube buckle (3) is an annular protruding structure, and a first spiral structure is provided on its outer surface.

3. The multifunctional perfusion needle for animal experiments according to claim 2, characterized in that: The buckle area (4) is a second spiral structure arranged on the inner side of the first covering tube section (21) and matched with the first spiral structure. When the needle tube body (1) rotates back into the first covering tube section (21), the needle tube body buckle (3) and the buckle area (4) are locked. When the needle tube body (1) rotates in the opposite direction and extends out of the first covering tube section (21), the needle tube body buckle (3) and the buckle area (4) are unlocked.

4. The multifunctional perfusion needle for animal experiments according to claim 1, characterized in that: The expansion pipe section (22) is an elastic pipe section, which, after being compressed, extends outward in the circumferential direction to form a bulge.

5. The multifunctional perfusion needle for animal experiments according to claim 1, characterized in that: The first cladding pipe section (21) and the second cladding pipe section (23) are rigid pipe sections.

6. The multifunctional perfusion needle for animal experiments according to claim 1, characterized in that: The fixing portion (5) is a bolt extrusion fixing portion, which includes a screw threadedly connected to the side wall of the second covering tube section (23), and a rotating head provided at the outer end of the screw at the second covering tube section (23). By rotating the rotating head, the screw is brought into contact with the needle tube body (1), thereby fixing the relative positions of the covering tube (2) and the needle tube body (1).

7. The multifunctional perfusion needle for animal experiments according to claim 1, characterized in that: The fixing portion (5) is a pressing and locking fixing portion, which includes a pressing rod penetrating the side wall of the second covering tube section (23), and a pressing head arranged at the outer end of the pressing rod at the second covering tube section (23). By pressing the pressing head, the pressing rod is brought into contact with the needle tube body (1), thereby fixing the relative positions of the covering tube (2) and the needle tube body (1).

8. The multifunctional perfusion needle for animal experiments according to claim 1, characterized in that: The needle tip of the needle is a beveled needle tip.

9. The multifunctional perfusion needle for animal experiments according to claim 1, characterized in that: The outer diameter of the needle tube (1) is consistent with the inner diameter of the covering tube (2).

10. The multifunctional perfusion needle for animal experiments according to claim 1, characterized in that: The connector (6) is a standard Luer connector made of medical plastic or medical stainless steel, and is used to connect an ordinary syringe or an infusion tube.

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