Centrifugal platform and centrifugal equipment
By designing an automated centrifugal platform and equipment, and using manipulators and transposition components to achieve automatic transfer of samples and adapters, the problems of high labor costs and low efficiency of existing centrifugal equipment have been solved, and efficient and reliable large-scale sample centrifugation has been achieved.
Patent Information
- Application Number
- CN202422580219.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-24
- Publication Date
- 2025-09-30
- Estimated Expiration
- 2034-10-24
AI Technical Summary
Existing centrifugation equipment has high labor costs and low efficiency, and cannot meet the centrifugation needs of large quantities of samples.
A centrifugal platform is designed, which includes a sample injection part, a sample discharge part, a centrifuge position, an adapter management module and a sample transfer module. A manipulator and a transposition component are used to realize the automatic transfer of samples and adapters, including an adapter carrying component and a guide plate area, to automatically complete the transfer of samples from the injection part to the centrifuge adapter and the automatic transfer of the centrifuge adapter between different positions.
The sample transfer step is simple and efficient, which reduces labor costs, improves operational reliability, avoids biological contamination and manual operation errors, and meets the needs of large-scale sample centrifugation.
Smart Images

Figure CN223393611U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of centrifugation, in particular to a centrifugal platform and centrifugal equipment. Background Art
[0002] A centrifuge uses centrifugal force to separate components in a mixture of liquids and solid particles or liquids and liquids. It can be used to separate biological cells, tissues, bacteria, etc., and is widely used in chemistry, chemical engineering, medicine, food, pharmaceuticals and other fields. For example, in experiments in biology, medicine and other fields, it is often necessary to centrifuge blood samples, and a centrifuge is usually used to perform this part of the work. In related technologies, staff manually place the samples into the centrifuge tray in turn, then place the centrifuge tray into the centrifuge for centrifugal stratification, and then manually remove the separated centrifuge tray. This processing method is inefficient and has high labor costs, and cannot meet the centrifugation needs of large quantities of samples.
[0003] Therefore, it is necessary to provide a new solution to solve the above technical problems. Utility Model Content
[0004] In view of the above-mentioned shortcomings of the prior art, the purpose of the present invention is to provide a centrifugal platform and centrifugal equipment to solve the problems of high labor costs, low efficiency and inability to meet the centrifugation needs of large quantities of samples in the related art.
[0005] To achieve the above-mentioned and other related purposes, the present invention provides a centrifugal platform, comprising a platform body having a working surface, a sample inlet, a sample outlet, a centrifuge position, an adapter management module, and a sample transfer module arranged on the working surface;
[0006] The centrifuge position is provided for configuring a centrifuge;
[0007] The adapter management module includes an adapter carrying assembly and an adapter guide plate area. The adapter carrying assembly includes a transposition component, and a first carrying member and a second carrying member located at opposite ends of the transposition component. The first carrying member and the second carrying member are respectively configured to carry a centrifugal adapter, with the first carrying member being close to the sample inlet and the second carrying member being close to the sample outlet.
[0008] The sample transfer module is configured to transfer the sample to be centrifuged from the sample inlet to the first centrifuge adapter located on the first carrier; and perform the following guide plate operation after the centrifuge completes one centrifugation: transfer the second centrifuge adapter that has completed centrifugation in the centrifuge to the adapter guide plate area, transfer the first centrifuge adapter carrying the sample to be centrifuged into the centrifuge, and then transfer the second centrifuge adapter in the adapter guide plate area to the first carrier;
[0009] The switching component is configured to reverse the first and second carriers after the second centrifugal adapter is carried on the first carrier, so that after the reverse, the first carrier is close to the sample outlet as the second carrier, and the second carrier is close to the sample inlet as the first carrier;
[0010] The sample transfer module is further configured to transfer the centrifuged sample in the second centrifuge adapter to the sample outlet.
[0011] Optionally, the sample transfer module includes a first manipulator and a second manipulator, the first manipulator is configured to transfer the sample to be centrifuged from the sample inlet part to the first carrier, and the second manipulator is configured to transfer the sample after centrifugation in the second centrifuge adapter to the sample outlet; and the first manipulator is configured to perform the guide plate operation, and / or the second manipulator is configured to perform the guide plate operation, and / or the first manipulator and the second manipulator are configured to jointly perform the guide plate operation.
[0012] Optionally, the first manipulator is further configured to transfer the centrifuged sample in the second centrifuge adapter to the sample outlet, and / or the second manipulator is further configured to transfer the to-be-centrifuged sample from the sample inlet to the first carrier.
[0013] Optionally, the sample inlet and the sample outlet are arranged opposite to each other, and the adapter management module is arranged between the sample inlet and the sample outlet.
[0014] Optionally, the injection portion includes a first injection channel and a second injection channel connected end to end, the first injection channel is configured to transmit a first type of sample, and the second injection channel is configured to transmit a second type of sample;
[0015] And / or, a first distribution module is provided at the inlet end of the sample injection part, and the first distribution module is configured to distribute the sample to be centrifuged to the sample injection part.
[0016] Optionally, the adapter guide tray area is provided with an adapter carrying area; the sample transfer module is configured to perform the following guide tray operations after the centrifuge completes one centrifugation: sequentially transfer a second centrifugal adapter that has completed centrifugation in the centrifuge to the adapter carrying area, transfer a first centrifugal adapter carrying the sample to be centrifuged into the centrifuge, and then transfer the second centrifugal adapter in the adapter carrying area to the first carrying member;
[0017] Alternatively, the adapter guide plate area is provided with n adapter carrying areas; the sample transfer module is configured to perform the following guide plate operations after the centrifuge completes one centrifugation: sequentially transferring the n second centrifugal adapters that have completed centrifugation in the centrifuge to the adapter carrying area, transferring the n first centrifugal adapters carrying the samples to be centrifuged into the centrifuge, and then transferring the n second centrifugal adapters in the adapter carrying area to the first carrying member; the n is greater than or equal to 2.
[0018] Optionally, a cache portion is further provided on the working surface, and the cache portion is located between the sample inlet portion and the sample outlet portion, and is configured to receive the sample carrier from the sample inlet portion and provide the sample carrier to the sample outlet portion.
[0019] Optionally, the transposition component includes a rotary driving member and a rotating member connected to the driving end of the rotary driving member, the first bearing member and the second bearing member are located at opposite ends of the rotating member, and the rotary driving member drives the rotating member to rotate to drive the first bearing member and the second bearing member to rotate and reverse.
[0020] Optionally, the first carrier is provided with greater than or equal to N first adapter areas for carrying the first centrifugal adapter, and the second carrier is provided with greater than or equal to N second adapter areas for carrying the second centrifugal adapter, where N is the number of centrifuge adapters supported by the centrifuge.
[0021] The present application also provides a centrifugal device, comprising a centrifuge and the centrifugal platform as described above, wherein the centrifuge is configured at the centrifuge position.
[0022] The utility model provides a centrifugal platform and centrifugal equipment, which have the following beneficial effects:
[0023] The centrifuge platform includes a sample inlet, a sample outlet and a centrifuge position for configuring a centrifuge, and also includes an adapter management module and a sample transfer module. The adapter management module includes an adapter carrying component and an adapter guide plate area. The adapter carrying component includes a transposition component, and a first carrier and a second carrier located at opposite ends of the transposition component; the sample transfer module can transfer the sample to be centrifuged from the sample inlet to the first centrifuge adapter located on the first carrier; and perform the following guide plate operations after the centrifuge completes one centrifugation: transfer the second centrifuge adapter that has completed centrifugation in the centrifuge to the adapter guide plate area, transfer the first centrifuge adapter carrying the sample to be centrifuged into the centrifuge, and then transfer the second centrifuge adapter in the adapter guide plate area Transfer to the first carrier; the switching component is used to reverse the first carrier and the second carrier when the first carrier is fully loaded with the second centrifugal adapter. After the reversal, the first carrier serves as the second carrier and the second carrier serves as the first carrier; the sample transfer module is also used to transfer the sample after centrifugation in the second centrifugal adapter to the sample outlet; it can be seen that the centrifugal platform and the centrifugal device can realize the automatic transfer of the sample from the sample inlet to the centrifugal adapter, and the automatic transfer of the centrifugal adapter between the first carrier, the centrifuge, the second carrier and the sample outlet. The sample transfer steps are simple, and compared with manual operation, the cost is lower and the efficiency is higher. It can also avoid biological contamination and manual errors caused by manual operation, and has higher reliability. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] Figure 1 Shown is a structural schematic diagram of an assembly line centrifugal system according to an embodiment of the present utility model.
[0025] Description of Reference Numerals
[0026] 1- Platform body;
[0027] 2-injection part; 21-first injection channel; 22-second injection channel; 23-first distribution module; 24-second distribution module;
[0028] 3-Sample production department;
[0029] 4- Centrifuge position;
[0030] 5-Adapter management module; 51-Adapter guide plate area; 52-Transposition component; 521-Rotating member; 53-First bearing member; 54-Second bearing member;
[0031] 6-sample transfer module; 61-first manipulator; 62-second manipulator; 63-slide; 64-crossbeam;
[0032] 7-trim seat;
[0033] 8-Cache unit. DETAILED DESCRIPTION
[0034] The following describes the embodiments of the present invention through specific examples. Those skilled in the art will readily understand the other advantages and benefits of the present invention from the disclosure herein. The present invention may also be implemented or applied through various other specific embodiments, and the details in this specification may be modified or altered based on different perspectives and applications without departing from the spirit of the present invention.
[0035] It should be noted that the diagrams provided in the present embodiment are only for the purpose of illustrating the basic concept of the present invention. Therefore, the diagrams only show the components related to the present invention and are not drawn according to the number, shape and size of the components in actual implementation. The form, quantity and proportion of each component can be changed at will during actual implementation, and the component layout form may also be more complex. The structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the content disclosed in the specification for people familiar with this technology to understand and read. They are not used to limit the limiting conditions for the implementation of the present invention. Therefore, they have no technical significance. Any modification of the structure, change of the proportional relationship or adjustment of the size should still fall within the scope of the technical content disclosed in the present invention without affecting the effect and purpose of the present invention. At the same time, the terms such as "upper", "lower", "left", "right", "middle" and "one" quoted in this specification are only for the convenience of description and are not used to limit the scope of the implementation of the present invention. Changes or adjustments in their relative relationships should also be considered as the scope of the implementation of the present invention without substantially changing the technical content.
[0036] like Figure 1 As shown, some embodiments of the present application provide a centrifugal platform, which can be used in the fields of chemistry, chemical industry, medicine, food, and pharmaceuticals, and includes a platform body 1 with a working surface, on which are provided a sample inlet part 2, a sample outlet part 3, a centrifuge position 4, an adapter management module 5, and a sample transfer module 6.
[0037] The centrifuge position 4 is equipped with a centrifuge, which centrifuges the sample to be centrifuged.
[0038] The adapter management module 5 includes an adapter carrying assembly and an adapter guide plate area 51. The adapter carrying assembly includes a transposition component 52, and a first carrier 53 and a second carrier 54 located at opposite ends of the transposition component 52. The first carrier 53 and the second carrier 54 are both used to carry the centrifuge adapter, and the first carrier 53 is close to the sample inlet part 2, and the second carrier 54 is close to the sample outlet part 3.
[0039] The sample transfer module 6 transfers the sample to be centrifuged from the sample inlet 2 to the first centrifuge adapter located on the first carrier 53. After the centrifuge completes one centrifugation, it performs the following guide plate operation: it transfers the second centrifuge adapter that has completed centrifugation in the centrifuge to the adapter guide plate area 51, then transfers the first centrifuge adapter carrying the sample to be centrifuged into the centrifuge, and finally transfers the second centrifuge adapter in the adapter guide plate area 51 to the first carrier 53. At this point, the sample transfer module 6 completes the transfer of the sample to be centrifuged from the sample inlet 2 to the centrifuge for centrifugation, and transfers the sample that has completed centrifugation in the centrifuge to the first carrier 53, thus achieving automatic transfer of the sample from the sample inlet to the centrifuge adapter, and automatic transfer of the centrifuge adapter between the first carrier 53, the centrifuge, and the second carrier 54.
[0040] The repositioning component 52 is used to reverse the orientation of the first and second carriers 53 and 54 after the second centrifuge adapter is loaded onto the first carrier 53. After the repositioning, the first carrier 53 is positioned closer to the sample outlet 3 as the second carrier 54, while the second carrier 54 is positioned closer to the sample inlet 2 as the first carrier 53. At this point, the empty centrifuge adapter on the first carrier 53 serves as the first centrifuge adapter, used to load the sample to be centrifuged; the centrifuge adapter on the second carrier 54 serves as the second centrifuge adapter, loaded with the centrifuged sample.
[0041] Subsequently, the sample transfer module 6 transfers the centrifuged sample in the second centrifuge adapter to the sample outlet 3. Thus, the centrifuge platform and centrifuge apparatus provided in this embodiment can automatically transfer the sample from the sample inlet 2 to the centrifuge adapter, and automatically transfer the centrifuge adapter between the first carrier 53, the centrifuge, the second carrier 54, and the sample outlet 3. The sample transfer process is simple, and compared to manual operation, it is less costly and more efficient. Furthermore, it can avoid biological contamination and manual errors caused by manual operation, and has higher reliability.
[0042] In some embodiments, the first carrier 53 is provided with N or more first adapter areas, each of which is used to carry a first centrifugal adapter. The second carrier 54 is provided with N or more second adapter areas, each of which is used to carry a second centrifugal adapter. N here is the number of centrifugal adapters supported by the centrifuge. For example, in one application scenario, the centrifuge supports but is not limited to 4 centrifugal adapters, that is, the centrifuge can perform centrifugal operations on samples fixed on up to 4 centrifugal adapters at a time. In this application scenario, the first carrier 53 is provided with 4 or more first adapter areas, and the second carrier 54 is provided with 4 or more second adapter areas. The specific number of the first adapter areas and the second adapters is set according to actual needs, and can be 4, 5, 6, etc. Optionally, in some examples, in order to ensure the stability of the transposition component 52 when reversing the first carrier 53 and the second carrier 54, the number of the first adapter areas and the second adapter areas is set in a one-to-one correspondence.
[0043] In an application example of this embodiment, N first adapter areas are provided on the first carrier 53, and N second adapter areas are provided on the second carrier 54. For example, in an application scenario, a centrifuge supports, but is not limited to, four centrifuge adapters. The first carrier 53 is provided with four first adapter areas, and the second carrier 54 is provided with four second adapter areas.
[0044] It should be noted that, when there are multiple first adapter zones, in some examples, when each first adapter zone is switched by the sample transfer module 6 to carry a second centrifugal adapter with a centrifuged sample (i.e., the first adapter zone was originally empty, or originally carried a first centrifugal adapter to be centrifuged, and later the first adapter zone is replaced by a second centrifugal adapter), the switching component 52 switches the orientation of the first carrier 53 and the second carrier 54, i.e., switches the orientation of the empty second centrifugal adapter carried by the second adapter zone on the second carrier 54 with the second centrifugal adapter fully loaded with a centrifuged sample carried by the first adapter zone on the first carrier 53. In other examples, the switching component 52 may also switch the orientation of the first carrier and the second carrier 54 when at least a portion of the first adapter zones are switched by the sample transfer module 6 to carry a second centrifugal adapter with a centrifuged sample.
[0045] In some embodiments, the adapter guide plate area 51 is provided with an adapter carrying area, and the sample transfer module is configured to perform the following guide plate operations after the centrifuge completes one centrifugation: sequentially transfer a second centrifugal adapter that has completed centrifugation in the centrifuge to the adapter carrying area, transfer a first centrifugal adapter carrying a sample to be centrifuged into the centrifuge, and then transfer the second centrifugal adapter in the adapter carrying area to the first carrier 53; that is, complete the transfer of the second centrifugal adapters in the centrifuge between the adapter guide plate area 51 and the first carrier 53 one by one, and transfer the next second centrifugal adapter after transferring one second centrifugal adapter.
[0046] In other embodiments, the adapter guide tray area 51 is provided with n adapter loading areas, and the sample transfer module is configured to perform the following guide tray operations after the centrifuge completes a single centrifugation: sequentially transferring n second centrifuge adapters that have completed centrifugation within the centrifuge to the adapter loading areas, transferring n first centrifuge adapters carrying samples to be centrifuged into the centrifuge, and finally transferring n second centrifuge adapters from the adapter loading areas to the first loading member 53. In other words, the transfer of the second centrifuge adapters within the centrifuge between the adapter guide tray area 51 and the first loading member 53 is completed in groups of n, and after completing the transfer of one group of second centrifuge adapters, the next group of second centrifuge adapters is transferred (the number of second centrifuge adapters in the next group of second centrifuge adapters can be equal to or less than n). Of course, in this embodiment, the transfer of the second centrifuge adapters within the centrifuge between the adapter guide tray area 51 and the first loading member 53 can also be completed one by one, and after completing the transfer of one second centrifuge adapter, the next second centrifuge adapter is transferred. In some embodiments of this embodiment, the value of n can be equal to or less than N.
[0047] For example, in one application example, assume that there are four first adapter areas and the adapter guide area 51 has two adapter carrying areas. After the four first adapter areas are fully loaded with four first centrifuge adapters, the sample transfer module 6 removes two centrifuged second centrifuge adapters from the centrifuge and transfers them to the two adapter carrying areas. The two first centrifuge adapters loaded with samples to be centrifuged are then transferred to the centrifuge. The two second centrifuge adapters located in the two adapter carrying areas are then transferred to the first adapter area where the two first centrifuge adapters placed in the centrifuge were originally located. The two first centrifuge adapters carried by the remaining two first adapter areas are then transferred to the centrifuge in the same manner as described above. If the number of first adapter areas exceeds the number of adapter guide areas 51, the first centrifuge adapters carried by the first adapter areas are exchanged with the second centrifuged centrifuge adapters in the centrifuge in accordance with the number of adapter guide areas 51, as described above.
[0048] For example, in another application example, when there are four first adapter areas and four adapter carrying areas, after the four first adapter areas are fully loaded with the four first centrifuge adapters, the sample transfer module 6 removes four centrifuged second centrifuge adapters from the centrifuge and transfers them to the four adapter carrying areas. The four first centrifuge adapters loaded with samples to be centrifuged are then transferred back into the centrifuge. Finally, the four second centrifuge adapters in the four adapter carrying areas are transferred to the first adapter area where the first centrifuge adapters were originally located. When the number of first adapter areas and adapter guide plate area 51 matches, the first centrifuge adapters in the first adapter areas are exchanged with the second centrifuge adapters in the centrifuge as described above.
[0049] In some embodiments, the transposition component 52 includes a rotary drive member (not shown) and a rotating member 521. The rotating member 521 is connected to the driving end of the rotary drive member so that the rotary drive member can drive the rotating member to rotate. A first carrier 53 and a second carrier 54 are mounted on each end of the rotating member 521. When the rotary drive member drives the rotating member 521 to rotate, the first carrier 53 and the second carrier 54 rotate in opposite directions, thereby simplifying the guide tray operation of the sample transfer module 6.
[0050] For example, the rotary drive member may be mounted on the platform body 1. The rotary drive member provides driving force for the rotation of the rotary member, including but not limited to being configured as a rotary cylinder, a servo motor, and the like.
[0051] It should be noted that trim seats 7 are mounted on both sides of the rotating member 521, and trim tubes are placed inside the trim seats 7. When the sample to be centrifuged cannot fill the first centrifuge adapter, the sample transfer module 6 transfers the trim tubes to the first centrifuge adapter, completing the trimming operation of the first centrifuge adapter and ensuring normal centrifugal operation of the centrifuge.
[0052] Illustratively, both the first and second adapter regions are provided with limit structures to prevent the first and second centrifugal adapters from falling off the rotating member 521 during rotation. Furthermore, a weighing sensor mechanism is provided below the first and second bearing members 53 and 54 to weigh the first centrifugal adapter and thereby perform a balancing operation on the first centrifugal adapter.
[0053] In some embodiments, the sample transfer module 6 includes a first manipulator 61 and a second manipulator 62. The first manipulator 61 is used for the injection of samples to be centrifuged, that is, transferring the samples to be centrifuged from the injection portion 2 to the first carrier 53, and the second manipulator 62 is used for the discharge of samples after centrifugation, that is, transferring the samples after centrifugation in the second centrifugal adapter to the sample discharge portion 3. In some examples, at least part of the injection and discharge operations of the first manipulator 61 and the second manipulator 62 can be performed in parallel and simultaneously, which is conducive to maximizing the sample throughput. Of course, in other examples, all processes of the injection and discharge operations of the first manipulator 61 and the second manipulator 62 can also be non-overlapping in time.
[0054] In some embodiments, at least one of the first manipulator 61 and the second manipulator is further configured to perform the aforementioned tray guiding operation. For example, in some application scenarios, the first manipulator 61 performs the aforementioned tray guiding operation; in another application scenario, the second manipulator 62 performs the aforementioned tray guiding operation; and in yet another application scenario, the first manipulator 61 and the second manipulator 62 can jointly perform the tray guiding operation, thereby facilitating improved efficiency in the entry of samples to be centrifuged into the centrifuge, thereby facilitating improved centrifugal efficiency of the centrifuge configured in the centrifuge position 4.
[0055] For example, in one embodiment, the first manipulator 61 transfers a sample to be centrifuged from the sample inlet 2 to the first centrifuge adapter on the first carrier 53. After the centrifuge completes a centrifugation cycle, the first manipulator 61 transfers a second centrifuge adapter that has completed centrifugation in the centrifuge to the adapter guide area 51. A first centrifuge adapter carrying a sample to be centrifuged is then transferred into the centrifuge. Finally, the second centrifuge adapter in the adapter guide area 51 is transferred back to the original position of the first centrifuge adapter on the first carrier 53. After the repositioning component 52 reverses the orientation of the first carrier 53 and the second carrier 54, the second manipulator 62 transfers the centrifuged sample from the second centrifuge adapter to the sample outlet 3.
[0056] For example, in another embodiment, the first manipulator 61 transfers a sample to be centrifuged from the sample inlet 2 to the first centrifuge adapter located on the first carrier 53. After the centrifuge completes a centrifugation cycle, the second manipulator 62 transfers a second centrifuge adapter that has completed centrifugation in the centrifuge to the adapter guide area 51. It then transfers a first centrifuge adapter carrying a sample to be centrifuged into the centrifuge. Finally, the second centrifuge adapter in the adapter guide area 51 is transferred to the original position of the first centrifuge adapter on the first carrier 53. After the repositioning component 52 reverses the orientation of the first carrier 53 and the second carrier 54, the second manipulator 62 transfers the centrifuged sample from the second centrifuge adapter to the sample outlet 3.
[0057] In some examples, the second manipulator 62 has already transferred the centrifuged sample in the second centrifuge adapter on the second carrier 54 to the sample outlet 3 before performing the plate guiding operation; or, the second manipulator 62 has not completely transferred the centrifuged sample in the second centrifuge adapter on the second carrier 54 to the sample outlet 3 before performing the plate guiding operation, and continues to transfer the remaining centrifuged sample in the second centrifuge adapter on the second carrier 54 to the sample outlet 3 after the plate guiding operation is completed.
[0058] Alternatively, in other examples, the first manipulator 61 transfers a sample to be centrifuged from the sample inlet 2 to the first centrifuge adapter located on the first carrier 53. After the first centrifuge adapter is fully balanced and the centrifuge completes a single centrifugation, the second manipulator 62 can transfer a second centrifuge adapter that has completed centrifugation within the centrifuge to the adapter guide area 51. The first manipulator 61 transfers a first centrifuge adapter carrying a sample to be centrifuged into the centrifuge, and then transfers the second centrifuge adapter within the adapter guide area 51 to the original position of the first centrifuge adapter on the first carrier 53. Alternatively, the first manipulator 61 and the second manipulator 62 can sequentially transfer a second centrifuge adapter that has completed centrifugation within the centrifuge to the adapter guide area 51, then transfer a first centrifuge adapter carrying a sample to be centrifuged into the centrifuge, and then transfer the second centrifuge adapter within the adapter guide area 51 to the original position of the first centrifuge adapter on the first carrier 53. Alternatively, the first manipulator 61 and the second manipulator 62 can jointly perform the guide operations in other ways. After the component to be replaced 52 changes the orientation of the first carrier 53 and the second carrier 54 , the second manipulator 62 is used to transfer the centrifuged sample on the second centrifuge adapter to the sample outlet 3 .
[0059] In some embodiments, the first manipulator 61 can also be used to remove samples after centrifugation, and the second manipulator 62 can also be used to inject samples to be centrifuged, that is, the first manipulator 61 and the second manipulator 62 can jointly perform injection and removal of samples, which is conducive to maximizing the sample throughput.
[0060] In some embodiments, in order to reduce the movement trajectory of the sample transfer module 6, the centrifuge position 4 and the adapter guide plate area 51 are both located between the first carrier 53 and the second carrier 54, and the two are arranged relative to each other, which is beneficial to improving the working efficiency of the sample transfer module 6.
[0061] In some embodiments, the sample transfer module 6 further includes two slideways 63 disposed opposite each other, with the adapter management module 5 located between the two slideways 63. The first manipulator 61 and the second manipulator 62 are both mounted on the two slideways 63 and are capable of sliding along the length of the slideways 63. The first manipulator 61 and the second manipulator 62 share the slideway 63, which helps shorten sample loading and unloading time and also helps reduce costs.
[0062] In some examples, in addition to being able to move along the length direction of the slide 63, the first manipulator 61 and the second manipulator 62 can also move in a direction perpendicular to the length direction of the slide 63. The first manipulator 61 and the second manipulator 62 are mounted on the beam 64 on the two slides 63 and are provided with slide rails, which is beneficial for the first manipulator 61 and the second manipulator 62 to cope with the situation where multiple first adapter areas and second adapter areas are provided at both ends of the rotating part 521, and is also beneficial for the first manipulator 61 and / or the second manipulator 62 to cope with the guide plate operation.
[0063] In some embodiments, the sample inlet 2 and the sample outlet 3 are disposed opposite each other, and an adapter management module 5 is disposed between the sample inlet 2 and the sample outlet 3. The first carrier 53 is located near the sample inlet 2, and the second carrier 54 is located near the sample outlet 3. This facilitates shortening the distance that the sample transfer module 6 must travel to transfer the sample to be centrifuged from the sample inlet 2 to the first carrier 53, and to transfer the centrifuged sample on the second carrier 54 to the sample outlet 3, thereby improving sample transfer efficiency.
[0064] In some embodiments, a first distribution module 23 is provided at the inlet of the sample inlet 2. When a sample is delivered to the first distribution module 23, the first distribution module 23 diverts the sample to be centrifuged to the sample inlet 2 and diverts the sample not to be centrifuged to the rear end of the sample outlet 3, thereby outputting the sample not to be centrifuged. The first distribution module 23 in this embodiment can be implemented by, but is not limited to, a paddle, a notched disc, or other structures.
[0065] In some embodiments, the sample introduction section 2 includes a first sample introduction channel 21 and a second sample introduction channel 22 connected end to end. The first sample introduction channel 21 is used to transport a first type of sample, and the second sample introduction channel 22 is used to transport a second type of sample. The first type of sample includes, but is not limited to, ordinary samples to be centrifuged, and the second type of sample includes, but is not limited to, emergency samples to be centrifuged or other samples requiring priority testing. The provision of the second sample introduction channel 22 allows for the centrifugation of the second type of sample without affecting the testing of the first type of sample, and facilitates increasing the number of first type sample tubes cached on the first sample introduction channel 21.
[0066] Illustratively, a second distribution module 24 is provided at the head end of the first sample injection channel 21 and the second sample injection channel 22. When the sample to be centrifuged is delivered to the second distribution module 24, the second distribution module 24 diverts the normal sample to be centrifuged to the first sample injection channel 21 and diverts the emergency sample to be centrifuged to the second sample injection channel 22. The second distribution module 24 in this embodiment can be implemented by, but is not limited to, a paddle, a notched disc, or other structures.
[0067] In some embodiments, a buffer section 8 is further provided on the work surface between the sample inlet 2 and the sample outlet 3. The buffer section has two ends connected to the rear end of the sample inlet 2 and the front end of the sample outlet 3, respectively. Sample carriers (e.g., empty sample holders) for holding samples flowing out of the sample inlet 2 are buffered in the buffer section 8 for subsequent output to the sample outlet 3 to hold the centrifuged samples.
[0068] In summary, the present invention provides a centrifugal platform, which includes a sample inlet, a sample outlet and a centrifuge position for configuring a centrifuge, and also includes an adapter management module and a sample transfer module. The adapter management module includes an adapter carrying component and an adapter guide plate area. The adapter carrying component includes a transposition component, and a first carrier and a second carrier located at opposite ends of the transposition component; the sample transfer module can transfer the sample to be centrifuged from the sample inlet to the first centrifuge adapter located on the first carrier; and perform the following guide plate operations after the centrifuge completes one centrifugation: transfer the second centrifuge adapter that has completed centrifugation in the centrifuge to the adapter guide plate area, transfer the first centrifuge adapter carrying the sample to be centrifuged into the centrifuge, and then transfer the adapter guide plate The second centrifugal adapter in the area is transferred to the first carrier; the replacement component is used to reverse the first carrier and the second carrier when the first carrier is fully loaded with the second centrifugal adapter. After the reversal, the first carrier serves as the second carrier and the second carrier serves as the first carrier; the sample transfer module is also used to transfer the sample after centrifugation in the second centrifugal adapter to the sample outlet; it can be seen that the centrifugal platform and the centrifugal device can realize the automatic transfer of the sample from the sample inlet to the centrifugal adapter, and the automatic transfer of the centrifugal adapter between the first carrier, the centrifuge, the second carrier and the sample outlet. The sample transfer steps are simple, and compared with manual operation, the cost is lower and the efficiency is higher. It can also avoid biological contamination and manual errors caused by manual operation, and has higher reliability.
[0069] Some embodiments of the present application further provide a centrifugal device, comprising a centrifuge and the above-mentioned centrifugal platform, wherein the centrifuge is arranged at the centrifuge position 4 of the centrifugal platform for centrifuging a sample to be centrifuged.
[0070] It should be noted that the centrifuge can perform centrifugal operations alone.
[0071] In some embodiments, to facilitate the insertion and removal of centrifuge adapters by sample transfer module 6, a material removal port is provided on the working surface, corresponding to the centrifuge's inlet and outlet ports. A second centrifuge adapter, having completed centrifugation in the centrifuge, is rotated to the inlet and outlet ports, allowing sample transfer module 6 to transfer the second centrifuge adapter. Subsequently, sample transfer module 6 transfers the first centrifuge adapter to the second centrifuge adapter's original location in the centrifuge.
[0072] The above embodiments are merely illustrative of the principles and effects of the present invention and are not intended to limit the present invention. Anyone skilled in the art may modify or alter the above embodiments without departing from the spirit and scope of the present invention. Therefore, all equivalent modifications or alterations made by one of ordinary skill in the art without departing from the spirit and technical principles disclosed in the present invention are intended to be covered by the claims of the present invention.
Claims
1. A centrifugal platform, characterized in that: It includes a platform body with a working surface, a sample inlet, a sample outlet, a centrifuge position, an adapter management module and a sample transfer module arranged on the working surface; The centrifuge position is provided for configuring a centrifuge; The adapter management module includes an adapter carrying assembly and an adapter guide plate area. The adapter carrying assembly includes a transposition component, and a first carrying member and a second carrying member located at opposite ends of the transposition component. The first carrying member and the second carrying member are respectively configured to carry a centrifugal adapter, with the first carrying member being close to the sample inlet and the second carrying member being close to the sample outlet. The sample transfer module is configured to transfer the sample to be centrifuged from the sample inlet portion to a first centrifuge adapter located on the first carrier; and performing the following guide plate operation after the centrifuge completes one centrifugation: transferring the second centrifuge adapter that has completed centrifugation in the centrifuge to the adapter guide plate area, transferring the first centrifuge adapter carrying the sample to be centrifuged into the centrifuge, and then transferring the second centrifuge adapter in the adapter guide plate area to the first carrier; The switching component is configured to reverse the first and second carriers after the second centrifugal adapter is carried on the first carrier, so that after the reverse, the first carrier is close to the sample outlet as the second carrier, and the second carrier is close to the sample inlet as the first carrier; The sample transfer module is further configured to transfer the centrifuged sample in the second centrifuge adapter to the sample outlet.
2. The centrifugal platform according to claim 1, characterized in that: The sample transfer module includes a first manipulator and a second manipulator, the first manipulator is configured to transfer the sample to be centrifuged from the sample inlet part to the first carrier, and the second manipulator is configured to transfer the sample after centrifugation in the second centrifuge adapter to the sample outlet; and the first manipulator is configured to perform the guide plate operation, and / or the second manipulator is configured to perform the guide plate operation, and / or the first manipulator and the second manipulator are configured to jointly perform the guide plate operation.
3. The centrifugal platform according to claim 2, characterized in that: The first manipulator is further configured to transfer the centrifuged sample in the second centrifuge adapter to the sample outlet, and / or the second manipulator is further configured to transfer the to-be-centrifuged sample from the sample inlet to the first carrier.
4. The centrifugal platform according to claim 1, characterized in that: The sample inlet and the sample outlet are arranged opposite to each other, and the adapter management module is arranged between the sample inlet and the sample outlet.
5. The centrifugal platform according to any one of claims 1 to 4, characterized in that: The injection portion includes a first injection channel and a second injection channel connected end to end, the first injection channel is configured to transmit a first type of sample, and the second injection channel is configured to transmit a second type of sample; And / or, a first distribution module is provided at the inlet end of the sample injection part, and the first distribution module is configured to distribute the sample to be centrifuged to the sample injection part.
6. The centrifugal platform according to any one of claims 1 to 4, characterized in that: The adapter guide plate area is provided with an adapter carrying area; the sample transfer module is configured to perform the following guide plate operations after the centrifuge completes one centrifugation: sequentially transferring a second centrifugal adapter that has completed centrifugation in the centrifuge to the adapter carrying area, transferring a first centrifugal adapter carrying the sample to be centrifuged into the centrifuge, and then transferring the second centrifugal adapter in the adapter carrying area to the first carrying member; Alternatively, the adapter guide plate area is provided with n adapter carrying areas; the sample transfer module is configured to perform the following guide plate operations after the centrifuge completes one centrifugation: sequentially transferring the n second centrifugal adapters that have completed centrifugation in the centrifuge to the adapter carrying area, transferring the n first centrifugal adapters carrying the samples to be centrifuged into the centrifuge, and then transferring the n second centrifugal adapters in the adapter carrying area to the first carrying member; the n is greater than or equal to 2.
7. The centrifugal platform according to any one of claims 1 to 4, characterized in that: A buffer portion is further provided on the working surface. The buffer portion is located between the sample inlet portion and the sample outlet portion and is configured to receive the sample carrier from the sample inlet portion and provide the sample carrier to the sample outlet portion.
8. The centrifugal platform according to any one of claims 1 to 4, characterized in that: The transposition component includes a rotary driving member and a rotating member connected to the driving end of the rotary driving member. The first bearing member and the second bearing member are located at opposite ends of the rotary member. The rotary driving member drives the rotating member to rotate to drive the first bearing member and the second bearing member to rotate and reverse.
9. The centrifugal platform according to any one of claims 1 to 4, characterized in that: The first carrier is provided with N or more first adapter areas for carrying the first centrifugal adapter, and the second carrier is provided with N or more second adapter areas for carrying the second centrifugal adapter, where N is the number of centrifuge adapters supported by the centrifuge.
10. A centrifugal device, characterized in that: It comprises a centrifuge and a centrifugal platform according to any one of claims 1 to 9, wherein the centrifuge is arranged at the centrifuge position.