Dropping, dyeing and sealing integrated equipment for HE dyeing liquid

The temperature of the HE dyeing solution is controlled by a temperature control component and a liquid level sensor, which solves the problem of uncontrollable temperature in the drip dyeing and sealing equipment, realizes efficient dyeing and sealing operations, and improves the dyeing effect and processing efficiency.

CN223400697UActive Publication Date: 2025-09-30JINRUIBO (XIAMEN) BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421939728.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-12
Publication Date
2025-09-30
Estimated Expiration
2034-08-12

AI Technical Summary

Technical Problem

Existing drip-staining and sealing equipment cannot control the temperature of the HE staining solution, resulting in unstable staining effects and low efficiency in processing tissue sections.

Method used

The temperature of the HE staining solution is controlled by a temperature control component and a temperature sensor, and a heater and a refrigerator are used to maintain the appropriate temperature. The automated operation of dripping and sealing is achieved through a liquid level sensor and a control valve.

Benefits of technology

Ensuring that the staining solution works at an appropriate temperature improves the stability and repeatability of the staining effect, while also increasing the efficiency of tissue section processing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the field of drip dyeing and sealing equipment, and discloses drip dyeing and sealing integrated equipment for HE dyeing liquid, which comprises a base, support frames are fixedly connected to the left side and the right side of the lower part of the base, a mounting frame is fixedly connected to the upper part of the base, and a conveying belt is fixedly connected to the upper middle part of the base. A liquid storage tank is fixedly connected to the upper portion of the mounting frame, a liquid inlet pipe is rotatably connected to the inner side of the upper portion of the liquid storage tank, a first control valve is fixedly connected to the outer side of the liquid inlet pipe, a temperature control assembly is fixedly connected to the outer side of the lower portion of the liquid inlet pipe, and a driving assembly is fixedly connected to the left side of the upper portion of the liquid storage tank. And the right side in the mounting frame is fixedly connected with a sealing module. According to the utility model, through the cooperation of the temperature sensor, the driving motor, the heater, the refrigerator and other structures, the dripping, dyeing and sealing integrated equipment can control the temperature of the HE dyeing liquid, and the dyeing liquid is ensured to work at a proper temperature, so that the stability and repeatability of the dyeing effect are improved.
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Description

Technical Field

[0001] The utility model relates to the field of drip dyeing and sealing equipment, in particular to an integrated drip dyeing and sealing equipment for HE dyeing liquid. Background Art

[0002] HE staining solution is a dye commonly used for staining histological sections. The purpose of drip staining is to make the tissue form a colored morphology. The purpose of sealing is to seal the tissue section between the slide and the cover slip to prevent it from contacting with the air, preventing it from oxidation and fading, and facilitating microscopic observation and preservation. The integrated drip staining and sealing equipment for HE staining solution is usually used in the field of histological staining, especially in medical and biological research, to process tissue sections for staining.

[0003] In the prior art, the integrated drip-dyeing and sealing equipment is often unable to control the temperature of the HE staining solution, unable to ensure that the staining solution works at an appropriate temperature, and has a low efficiency in processing tissue sections. Utility Model Content

[0004] In order to make up for the above shortcomings, the utility model provides an integrated drip-dyeing and sealing device for HE staining liquid, aiming to improve the problems in the existing technology that the integrated drip-dyeing and sealing device often cannot control the temperature of HE staining liquid, cannot ensure that the staining liquid works at an appropriate temperature, and has low processing efficiency for tissue sections.

[0005] In order to achieve the above-mentioned purpose, the present invention adopts the following technical scheme: a drip-dyeing and sealing integrated device for HE dyeing liquid, comprising a base, wherein the left and right sides of the lower part of the base are fixedly connected to support frames, the upper part of the base is fixedly connected to a mounting frame, the middle part of the base is fixedly connected to a conveyor belt, the upper part of the mounting frame is fixedly connected to a liquid storage tank, the inner side of the upper part of the liquid storage tank is rotatably connected to a liquid inlet pipe, the outer side of the liquid inlet pipe is fixedly connected to a control valve 1, the outer side of the lower part of the liquid inlet pipe is fixedly connected to a temperature control component, the left side of the upper part of the liquid storage tank is fixedly connected to a driving component, the right side of the inside of the mounting frame is fixedly connected to a sealing module, the left side of the inside of the mounting frame is fixedly connected to a drip-dyeing component, the left side of the lower part of the liquid storage tank is fixedly connected to an infusion pipe, and the outer side of the infusion pipe is fixedly connected to a control valve 2.

[0006] As a further description of the above technical solution:

[0007] The temperature control assembly includes a mounting plate, which is fixedly connected to the outer side of the lower part of the liquid inlet pipe. A heater is fixedly connected to the right side of the lower part of the mounting plate, a refrigerator is fixedly connected to the left side of the lower part of the mounting plate, and a temperature sensor is fixedly connected to the bottom of the liquid storage tank.

[0008] As a further description of the above technical solution:

[0009] The driving assembly includes a motor frame, which is fixedly connected to the upper left side of the liquid storage tank. A driving motor is fixedly connected inside the motor frame. The output end of the driving motor is fixedly connected to a second gear, and the right side of the second gear is meshed with a first gear.

[0010] As a further description of the above technical solution:

[0011] The drip dye assembly includes a fixing frame, which is fixedly connected to the left side of the mounting frame. A drip dye tank is fixedly connected to the inside of the fixing frame. A liquid outlet pipe is fixedly connected to the lower part of the drip dye tank. A liquid level sensor is fixedly connected to the upper part of the inner wall of the drip dye tank. A liquid baffle is fixedly connected to the middle part of the inner wall of the drip dye tank. A liquid guide tube is fixedly connected to the lower middle part of the liquid baffle. A valve is fixedly connected to the outer side of the liquid guide tube.

[0012] As a further description of the above technical solution:

[0013] The refrigerator is electrically connected to the temperature sensor, and the temperature sensor is electrically connected to the heater.

[0014] As a further description of the above technical solution:

[0015] The first gear is fixedly connected to the outer side of the upper middle portion of the liquid inlet pipe.

[0016] As a further description of the above technical solution:

[0017] The valve is electrically connected to the liquid level sensor, and the liquid level sensor is electrically connected to the control valve.

[0018] The utility model has the following beneficial effects:

[0019] In the utility model, a threshold value is set for the temperature sensor, and the heater and the refrigerator are used to control the temperature of the HE dyeing liquid through the heater, and then the drive motor is started to drive the second gear and the first gear to rotate, the first gear drives the liquid inlet pipe to rotate, the liquid inlet pipe drives the mounting plate to rotate, and the mounting plate drives the heater and the refrigerator to rotate, thereby realizing that the drip dyeing and sealing integrated equipment can control the temperature of the HE dyeing liquid, ensuring that the dyeing liquid works at an appropriate temperature, so as to improve the stability and repeatability of the dyeing effect.

[0020] In the utility model, a preset value is set for the liquid level sensor, and the second control valve is controlled to be opened so that the dyeing liquid in the liquid storage tank flows into the drip dye tank through the infusion tube. The second control valve is closed by the liquid level sensor and the valve is controlled to be opened at the same time, so that the dyeing liquid on the upper part of the liquid baffle is discharged into the inner side of the lower part of the drip dye tank through the liquid guide tube, and the HE dyeing liquid is discharged through the liquid outlet pipe to drip-dye the tissue slices, and the tissue slices are transported by the conveyor belt, and finally the tissue slices are sealed by the sealing module, thereby realizing that the drip dyeing and sealing integrated equipment can perform integrated processing on the tissue slices, thereby improving the processing efficiency of the tissue slices. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a three-dimensional diagram of an integrated device for dripping, dyeing and sealing slides for HE dyeing solution proposed in the present invention;

[0022] Figure 2 This is a front view of an integrated device for dripping, dyeing and sealing slides for HE dyeing solution proposed in the present invention;

[0023] Figure 3 This is a front view of an integrated device for dripping, dyeing and sealing slides for HE dyeing solution proposed in the present invention;

[0024] Figure 4 This is a front view of an integrated device for dripping, dyeing and sealing slides for HE dyeing solution proposed in the present invention;

[0025] Figure 5 This is a schematic diagram of a slide rail for an integrated device for dripping, dyeing and sealing slides with HE dyeing solution proposed in the present invention.

[0026] Legend:

[0027] 1. Base; 2. Support frame; 3. Mounting frame; 4. Conveyor belt; 5. Liquid storage tank; 6. Liquid inlet pipe; 7. Mounting plate; 8. Heater; 9. Refrigerator; 10. Temperature sensor; 11. Control valve 1; 12. First gear; 13. Motor frame; 14. Drive motor; 15. Second gear; 16. Fixed frame; 17. Drip tank; 18. Infusion tube; 19. Control valve 2; 20. Liquid level sensor; 21. Liquid baffle; 22. Liquid guide tube; 23. Valve; 24. Liquid outlet pipe; 25. Sealing module. DETAILED DESCRIPTION

[0028] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0029] Reference Figure 1-3 The utility model provides an embodiment: an integrated device for dripping and sealing HE dyeing liquid, comprising a base 1, a support frame 2 is fixedly connected to the left and right sides of the lower part of the base 1, a mounting frame 3 is fixedly connected to the upper part of the base 1, a liquid storage tank 5 is fixedly connected to the upper inner side of the liquid storage tank 5, a liquid inlet pipe 6 is rotatably connected to the outer side of the liquid inlet pipe 6, a control valve 11 is fixedly connected to the outer side of the liquid inlet pipe 6, a sealing module 25 is fixedly connected to the right side of the mounting frame 3, a liquid infusion pipe 18 is fixedly connected to the left side of the lower part of the liquid storage tank 5, a control valve 2 19 is fixedly connected to the outer side of the infusion pipe 18, a temperature control component is fixedly connected to the outer side of the lower part of the liquid inlet pipe 6, and the temperature control component includes a mounting plate 7, which is fixedly connected to the liquid inlet pipe. On the outside of the lower part of the tube 6, a heater 8 is fixedly connected to the right side of the lower part of the mounting plate 7, a refrigerator 9 is fixedly connected to the left side of the lower part of the mounting plate 7, a temperature sensor 10 is fixedly connected to the bottom of the liquid storage tank 5, the refrigerator 9 is electrically connected to the temperature sensor 10, the temperature sensor 10 is electrically connected to the heater 8, and a drive assembly is fixedly connected to the left side of the upper part of the liquid storage tank 5. The drive assembly includes a motor frame 13, the motor frame 13 is fixedly connected to the left side of the upper part of the liquid storage tank 5, and a drive motor 14 is fixedly connected to the inside of the motor frame 13. The output end of the drive motor 14 is fixedly connected to a second gear 15, and the first gear 12 is meshed with the right side of the second gear 15. The first gear 12 is fixedly connected to the outside of the upper middle part of the liquid inlet pipe 6.

[0030] The equipment is supported by the support frame 2, the HE dyeing liquid inside the liquid storage tank 5 is replenished through the liquid inlet pipe 6, the liquid inlet pipe 6 is controlled by the control valve 11, and a threshold is set for the temperature sensor 10. When the temperature sensor 10 detects that the temperature of the HE dyeing liquid is lower than the threshold, the temperature sensor 10 controls the start of the heater 8 to heat the HE dyeing liquid. When the temperature sensor 10 detects that the temperature of the HE dyeing liquid is higher than the threshold, the temperature sensor 10 controls the start of the refrigerator 9 to cool the HE dyeing liquid. Then the start of the drive motor 14 is controlled to drive the second gear 15 to rotate, the second gear 15 drives the first gear 12 to rotate, the first gear 12 drives the liquid inlet pipe 6 to rotate, the liquid inlet pipe 6 drives the mounting plate 7 to rotate, and the mounting plate 7 drives the heater 8 and the refrigerator 9 to rotate, thereby realizing that the drip dyeing and sealing integrated equipment can control the temperature of the HE dyeing liquid, ensure that the dyeing liquid works at an appropriate temperature, and improve the stability and repeatability of the dyeing effect.

[0031] Reference Figure 4-5A conveyor belt 4 is fixedly connected to the middle part of the base 1, and a drip dye assembly is fixedly connected to the left side of the inside of the mounting frame 3. The drip dye assembly includes a fixed frame 16, which is fixedly connected to the left side of the inside of the mounting frame 3. A drip dye tank 17 is fixedly connected to the inside of the fixed frame 16, and a liquid outlet pipe 24 is fixedly connected to the lower part of the drip dye tank 17. A liquid level sensor 20 is fixedly connected to the upper part of the inner wall of the drip dye tank 17, a liquid baffle plate 21 is fixedly connected to the middle part of the inner wall of the drip dye tank 17, and a liquid guide tube 22 is fixedly connected to the lower middle part of the liquid baffle plate 21. A valve 23 is fixedly connected to the outside of the liquid guide tube 22, and the valve 23 is electrically connected to the liquid level sensor 20, and the liquid level sensor 20 is electrically connected to the control valve 2 19.

[0032] The tissue sections are conveyed by the conveyor belt 4. By setting a preset value for the liquid level sensor 20, the control valve 2 19 is controlled to be opened so that the dyeing liquid in the liquid storage tank 5 flows into the dripping tank 17 through the infusion tube 18. When the dyeing liquid on the upper part of the liquid baffle 21 reaches the preset value, the liquid level sensor 20 controls the closing of the control valve 2 19 and the opening of the valve 23 so that the dyeing liquid on the upper part of the liquid baffle 21 is discharged into the lower inner side of the dripping tank 17 through the liquid guide tube 22. The HE dyeing liquid is discharged through the liquid outlet pipe 24 to drip-dye the tissue sections. The tissue sections are conveyed by the conveyor belt 4 and finally sealed by the sealing module 25.

[0033] Working principle: When the temperature of the HE dyeing liquid needs to be controlled, first set a threshold value for the temperature sensor 10. When the temperature sensor 10 detects that the temperature of the HE dyeing liquid is lower than the threshold value, the temperature sensor 10 controls the start of the heater 8 to heat the HE dyeing liquid. When the temperature sensor 10 detects that the temperature of the HE dyeing liquid is higher than the threshold value, the temperature sensor 10 controls the start of the refrigerator 9 to cool the HE dyeing liquid. Then, the start of the drive motor 14 is controlled to drive the second gear 15 to rotate, the second gear 15 drives the first gear 12 to rotate, the first gear 12 drives the liquid inlet pipe 6 to rotate, the liquid inlet pipe 6 drives the mounting plate 7 to rotate, and the mounting plate 7 drives the heater 8 and the refrigerator 9 to rotate. In this way, the drop dyeing and sealing integrated equipment can control the temperature of the HE dyeing liquid to ensure the dyeing. The color liquid works at an appropriate temperature to improve the stability and repeatability of the dyeing effect. The tissue slices are placed on the upper part of the conveyor belt 4. When the tissue slices need to be dyed, the preset value is first set for the liquid level sensor 20, and the control valve 2 19 is controlled to open so that the dyeing liquid in the liquid storage tank 5 flows into the dripping tank 17 through the infusion tube 18. When the dyeing liquid on the upper part of the liquid baffle 21 reaches the preset value, the liquid level sensor 20 controls the closing of the control valve 2 19 and controls the opening of the valve 23 at the same time, so that the dyeing liquid on the upper part of the liquid baffle 21 is discharged into the lower inner side of the dripping tank 17 through the liquid guide tube 22, and the HE dyeing liquid is discharged through the liquid outlet pipe 24 to drip-dye the tissue slices. The tissue slices are transported by the conveyor belt 4 and finally sealed by the sealing module 25. In this way, the drip-dyeing and sealing integrated equipment can perform integrated processing on the tissue slices, thereby improving the processing efficiency of the tissue slices.

[0034] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent replacements for some of the technical features therein. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. An integrated device for dripping and sealing HE staining liquid, comprising a base (1), characterized in that: The left and right sides of the lower part of the base (1) are fixedly connected to support frames (2), the upper part of the base (1) is fixedly connected to a mounting frame (3), the upper middle part of the base (1) is fixedly connected to a conveyor belt (4), the upper part of the mounting frame (3) is fixedly connected to a liquid storage tank (5), the inner side of the upper part of the liquid storage tank (5) is rotatably connected to a liquid inlet pipe (6), the outer side of the liquid inlet pipe (6) is fixedly connected to a control valve 1 (11), the outer side of the lower part of the liquid inlet pipe (6) is fixedly connected to a temperature control component, the left side of the upper part of the liquid storage tank (5) is fixedly connected to a driving component, the right side of the inside of the mounting frame (3) is fixedly connected to a sealing module (25), the left side of the inside of the mounting frame (3) is fixedly connected to a dripping component, the left side of the lower part of the liquid storage tank (5) is fixedly connected to a liquid infusion pipe (18), and the outer side of the liquid infusion pipe (18) is fixedly connected to a control valve 2 (19).

2. The integrated device for dripping, dyeing and sealing of HE dyeing liquid according to claim 1, characterized in that: The temperature control assembly comprises a mounting plate (7), the mounting plate (7) being fixedly connected to the outer side of the lower portion of the liquid inlet pipe (6), a heater (8) being fixedly connected to the right side of the lower portion of the mounting plate (7), a refrigerator (9) being fixedly connected to the left side of the lower portion of the mounting plate (7), and a temperature sensor (10) being fixedly connected to the bottom of the liquid storage tank (5).

3. The integrated device for dripping, dyeing and sealing of HE dyeing liquid according to claim 1, characterized in that: The driving assembly comprises a motor frame (13), the motor frame (13) being fixedly connected to the upper left side of the liquid storage tank (5), a driving motor (14) being fixedly connected inside the motor frame (13), a second gear (15) being fixedly connected to the output end of the driving motor (14), and a first gear (12) being meshed on the right side of the second gear (15).

4. The integrated device for dripping, dyeing and sealing of HE dye according to claim 1, characterized in that: The drip dye assembly comprises a fixing frame (16), the fixing frame (16) is fixedly connected to the left side of the interior of the mounting frame (3), a drip dye tank (17) is fixedly connected to the interior of the fixing frame (16), a liquid outlet pipe (24) is fixedly connected to the lower portion of the drip dye tank (17), a liquid level sensor (20) is fixedly connected to the upper portion of the inner wall of the drip dye tank (17), a liquid baffle plate (21) is fixedly connected to the middle portion of the inner wall of the drip dye tank (17), a liquid guide pipe (22) is fixedly connected to the lower middle portion of the liquid baffle plate (21), and a valve (23) is fixedly connected to the outer side of the liquid guide pipe (22).

5. The integrated device for dripping, dyeing and sealing of HE dyeing liquid according to claim 2, characterized in that: The refrigerator (9) is electrically connected to the temperature sensor (10), and the temperature sensor (10) is electrically connected to the heater (8).

6. The integrated device for dripping, dyeing and sealing of HE dye according to claim 3, characterized in that: The first gear (12) is fixedly connected to the outer side of the upper middle portion of the liquid inlet pipe (6).

7. The integrated device for dripping, dyeing and sealing of HE dye according to claim 4, characterized in that: The valve (23) is electrically connected to the liquid level sensor (20), and the liquid level sensor (20) is electrically connected to the second control valve (19).

Citation Information

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