Tissue crushing device for gene detection

The spiral cutter and shaft design solves the centrifugal problem caused by the rotation of the crushing blade, achieves full contact between the cutter and the tissue, and improves the crushing efficiency.

CN223405060UActive Publication Date: 2025-10-03WUHAN EIGHTH HOSPITAL (WUHAN ANORECTAL HOSPITAL)
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Patent Information

Application Number
CN202422561584.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-23
Publication Date
2025-10-03
Estimated Expiration
2034-10-23

AI Technical Summary

Technical Problem

In existing tissue pulverization devices, the rotation of the pulverization blade causes the solution to be centrifuged by inertia, and the tissue adheres to the inner wall of the test tube and cannot fully contact the blade, thus affecting the pulverization effect.

Method used

The spiral cutter design is adopted, combined with the rotating shaft to drive the cutter to move horizontally and the rotating plate to gather the tissue, preventing centrifugal effect and ensuring full contact between the cutter and the tissue.

Benefits of technology

It improves the effect of tissue pulverization, ensures full contact between the cutter and the tissue, avoids centrifugal phenomenon, and improves pulverization efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of tissue crushing, and discloses a tissue crushing device for gene detection, which comprises a bottom plate, an L-shaped frame mounted on the upper side of the bottom plate, a groove body arranged above the bottom plate, a threaded shaft mounted on the upper side of the L-shaped frame, a moving block sleeved on the outer side of the threaded shaft in a matching manner, a second motor connected to the lower side of the moving block, and a rotating shaft mounted at the shaft end of the second motor, a connecting sleeve is mounted on the outer side of the lower part of the rotating shaft; multiple groups of cutters are mounted on the outer side of the connecting sleeve; two connecting plates are installed on the outer side of the rotating shaft and located on the two opposite sides of the rotating shaft, rotating plates are rotationally installed on the lower side walls of the connecting plates, and limiting blocks are installed on the lower side walls of the connecting plates correspondingly. Compared with the prior art, the tissue cutting device has the advantages that the rotating shaft drives the multiple sets of cutters to rotate and transversely move at the same time, the situation that tissue is attached to the inner wall of a test tube due to the centrifugal effect generated by inertia is avoided, and when the cutters transversely move, the tissue is gathered towards the cutters through the rotating plate, so that the cutters make full contact with the tissue for cutting.
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Description

Technical Field

[0001] The utility model relates to the technical field of tissue crushing, in particular to a tissue crushing device for gene detection. Background Art

[0002] Genes are the basic units of heredity, DNA or RNA sequences that carry genetic information. Through replication, they transmit this information to the next generation, guiding protein synthesis to express the genetic information they carry, thereby controlling the expression of traits in individual organisms. Genetic testing is a DNA testing technique that uses specific equipment to examine DNA molecules in cells, analyzing the types of genes they contain, genetic defects, and whether their expression functions are normal. Laboratory testing of biological genes requires various preparatory procedures on biological tissues, such as tissue amplification and pulverization.

[0003] Most existing tissue crushing devices use crushing blades to stir and crush the tissue, so that the tissue is refined in the solution for observation and detection under a microscope. However, during crushing, due to the directional operation of the crushing blades, the solution rotates with the blades, which can easily produce a centrifugal effect due to inertia, causing the tissue to stick to the inner wall of the test tube and unable to fully contact the blades, affecting the crushing effect.

[0004] In response to the above technical problems, the present application proposes a tissue crushing device for genetic testing. Utility Model Content

[0005] 1. Technical Problems Solved

[0006] The technical problem to be solved by the present invention is the directional operation of the rotation of the crushing blade. As the blade rotates, the solution is easily centrifuged due to inertia, which causes the tissue to adhere to the inner wall of the test tube and cannot fully contact the blade.

[0007] 2. Technical Solution

[0008] To solve the above technical problems, the present invention provides a technical solution as follows: a tissue crushing device for genetic testing, comprising a base plate, an L-shaped frame installed on the upper side of the base plate, a trough body provided above the base plate, a trough cover installed on the upper side of the trough body, a threaded shaft installed on the upper side of the L-shaped frame, a moving block provided on the outer side of the threaded shaft in a threaded sleeve, a second motor connected to the lower side of the moving block, a rotating shaft installed at the end of the second motor shaft, a connecting sleeve installed on the outer side of the lower part of the rotating shaft, and multiple sets of cutters installed on the outer side of the connecting sleeve;

[0009] Two groups of connecting plates are installed on the outside of the rotating shaft and above the connecting sleeve. The two groups of connecting plates are located on opposite sides of the rotating shaft. A rotating plate is rotatably installed on the side of the lower side wall of the connecting plate away from the rotating shaft. Limiting blocks are respectively installed on the lower side wall of the connecting plate and on both sides of the rotating plate.

[0010] As an improvement, the trough body is a long strip structure with arc-shaped structures at both ends.

[0011] As an improvement, the plurality of groups of cutters are arranged in a spiral shape on the outside of the connecting sleeve, and the rotating plate does not contact the cutters.

[0012] As an improvement, a connecting block is installed on the lower side of the moving block, and the L-shaped frame is provided with a slideway 1 for the connecting block to slide through. The outer side of the connecting block is connected to a U-shaped connecting frame with matching bolts, and a horizontal plate is installed on the lower side of the U-shaped connecting frame, and the motor 2 is fixedly installed on the lower side of the horizontal plate.

[0013] As an improvement, support blocks are respectively installed at both ends of the threaded shaft, the lower side of the support block is fixedly installed on the upper side of the L-shaped frame, and a motor for driving the threaded shaft is installed on one group of the support blocks.

[0014] As an improvement, a controller is installed on the L-shaped frame, and the controller is connected to the motor 1 and the motor 2 respectively through wires.

[0015] As an improvement, the slot cover is provided with a second slideway for the rotating shaft to slide through.

[0016] As an improvement, a support frame is installed on the upper side of the bottom plate to fit into the trough body.

[0017] 3. Beneficial Effects

[0018] The advantages of the present invention over the prior art are that the rotating shaft drives the multiple groups of cutters to rotate and move laterally at the same time, thereby preventing the centrifugal effect caused by inertia from causing the tissue to adhere to the inner wall of the test tube. When the cutter moves laterally, the tissue is gathered toward the cutter by the rotating plate, which facilitates full contact between the cutter and the tissue for chopping. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 The utility model is a schematic diagram of the overall structure of a tissue crushing device for gene detection.

[0020] Figure 2 The utility model is a schematic diagram of the inner structure of an L-shaped frame of a tissue pulverizing device for gene detection.

[0021] Figure 3 The utility model is a schematic diagram of the shaft connection structure of a tissue pulverizing device for gene detection.

[0022] Figure 4The utility model is a schematic diagram of the tank structure of a tissue crushing device for gene detection.

[0023] Figure 5 The utility model is a schematic diagram of the slot cover structure of a tissue crushing device for gene detection.

[0024] As shown in the figure: 1. Base plate; 2. L-shaped frame; 3. Support frame; 4. Trough body; 5. Trough cover; 6. Threaded shaft; 7. Support block; 8. Motor 1; 9. Moving block; 10. Connecting block; 11. Slide 1; 12. U-shaped connecting frame; 13. Horizontal plate; 14. Motor 2; 15. Rotating shaft; 16. Connecting sleeve; 17. Cutter; 18. Controller; 19. Connecting plate; 20. Rotating plate; 21. Limit block; 22. Slide 2. DETAILED DESCRIPTION

[0025] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments; based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0026] As attached Figure 1 , Attachment Figure 4 and attached Figure 5 As shown, a tissue pulverizing device for genetic testing includes a base plate 1, a trough body 4 is provided above the base plate 1, and the trough body 4 is a long strip structure with arc-shaped structures at both ends. A trough cover 5 is installed on the upper side of the trough body 4 to prevent splashing from the trough body 4 during tissue pulverization. A support frame 3 is installed on the upper side of the base plate 1 to fit the trough body 4. The support frame 3 supports the trough body 4 and facilitates the positioning of the trough body 4.

[0027] As attached Figure 3 As shown, an L-shaped frame 2 is installed on the upper side of the base plate 1, and a threaded shaft 6 is installed on the upper side of the L-shaped frame 2. A moving block 9 is provided on the outer side of the threaded shaft 6 in cooperation with the threaded sleeve. A second motor 14 is connected to the lower side of the moving block 9. A rotating shaft 15 is installed on the shaft end of the second motor 14. A second slideway 22 for sliding through the rotating shaft 15 is provided on the slot cover 5. A connecting sleeve 16 is installed on the outer side of the lower part of the rotating shaft 15. Multiple groups of cutters 17 are installed on the outer side of the connecting sleeve 16. The multiple groups of cutters 17 are spirally arranged on the outer side of the connecting sleeve 16, so that the cut surfaces of the multiple groups of cutters 17 when rotated horizontally are closer, and the tissue chopping effect is better.

[0028] Two groups of connecting plates 19 are installed on the outside of the rotating shaft 15 and above the connecting sleeve 16. The two groups of connecting plates 19 are located on opposite sides of the rotating shaft 15. A rotating plate 20 is rotatably installed on the side of the lower side wall of the connecting plate 19 away from the rotating shaft 15. The rotating plate 20 does not contact the cutter 17, and the rotation of the rotating plate 20 will not affect the rotation of the cutter 17. Limit blocks 21 are respectively installed on the lower side wall of the connecting plate 19 and on both sides of the rotating plate 20.

[0029] With the above structure, the tissue and solution are placed inside the tank body 4, which is placed inside the L-shaped frame 2. The rotating shaft 15 passes through the second slide 22 on the tank cover 5 and is fixedly mounted on the shaft end of the second motor 14. The cutter 17 is placed inside the tank body 4. The second motor 14 is started, and the rotating shaft 15 is driven by the second motor 14 to rotate, which in turn drives the multiple sets of cutters 17 to rotate.

[0030] The threaded shaft 6 rotates to drive the moving block 9 to move horizontally, and the moving block 9 drives the motor 2 14, the rotating shaft 15 and the multiple groups of cutters 17 to move horizontally. The connecting plate 19 installed on the outside of the rotating shaft 15 drives the rotating plate 20 and the cutter 17 to move simultaneously. The two groups of rotating plates 20 are in contact with the opposite side walls of the tank body 4 respectively. When the rotating plate 20 moves, it is pushed by the solution and tissue to rotate. The rotating plate 20 is supported by the limit block 21 so that the rotating plate 20 is in an inclined state. The solution and tissue move between the two groups of rotating plates 20, so that the tissue is fully in contact with the cutter 17 for shredding. The specific structure is as follows:

[0031] Combined with attachment Figure 2 and attached Figure 3 As shown, a connecting block 10 is installed on the lower side of the moving block 9, and a slideway 11 is provided on the L-shaped frame 2 for the connecting block 10 to slide through. A U-shaped connecting frame 12 is connected to the outer side of the connecting block 10 by bolts, and a horizontal plate 13 is installed on the lower side of the U-shaped connecting frame 12. The motor 2 14 is fixedly installed on the lower side of the horizontal plate 13.

[0032] Through the above structure, motor 2 14 is fixedly installed on the lower side of the horizontal plate 13, and is sleeved on the outside of the connecting block 10 through the U-shaped connecting frame 12. Multiple groups of bolts are passed through the U-shaped connecting frame 12 and the connecting block 10 to connect them, thereby achieving a fixed connection between motor 2 14 and the connecting block 10.

[0033] Combined with attachment Figure 1 As shown, support blocks 7 are respectively installed at both ends of the threaded shaft 6, and the lower side of the support block 7 is fixedly installed on the upper side of the L-shaped frame 2. A motor 8 for driving the threaded shaft 6 is installed on one group of the support blocks 7, and a controller 18 is installed on the L-shaped frame 2. The controller 18 is connected to the motor 1 8 and the motor 2 14 respectively with wires.

[0034] Through the above structure, the controller 18 controls the start, stop and direction of motor 1 8 and motor 2 14, and the motor 1 8 drives the threaded shaft 6 to rotate in different directions, thereby realizing the horizontal reciprocating movement of the moving block 9.

[0035] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that includes a list of elements includes not only those elements but also other elements not explicitly listed, or elements inherent to such process, method, article, or apparatus.

[0036] Although the embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

[0037] The above description of the present invention and its embodiments is non-limiting. The drawings show only one embodiment of the present invention, and the actual structure is not limited thereto. In short, if a person skilled in the art is inspired by the above, and does not deviate from the purpose of the present invention, without creatively designing a structure and embodiment similar to the technical solution, they shall fall within the scope of protection of the present invention.

Claims

1. A tissue pulverizing device for genetic testing, comprising a base plate (1), an L-shaped frame (2) being mounted on the upper side of the base plate (1), characterized in that: A trough body (4) is provided above the bottom plate (1), a trough cover (5) is installed on the upper side of the trough body (4), a threaded shaft (6) is installed on the upper side of the L-shaped frame (2), a moving block (9) is provided on the outer side of the threaded shaft (6) in conjunction with a threaded sleeve, a second motor (14) is connected to the lower side of the moving block (9), a rotating shaft (15) is installed on the shaft end of the second motor (14), a connecting sleeve (16) is installed on the outer side of the lower part of the rotating shaft (15), and a plurality of cutting knives (17) are installed on the outer side of the connecting sleeve (16); Two groups of connecting plates (19) are installed outside the rotating shaft (15) and above the connecting sleeve (16). The two groups of connecting plates (19) are located on opposite sides of the rotating shaft (15). A rotating plate (20) is rotatably installed on the side of the lower side wall of the connecting plate (19) away from the rotating shaft (15). Limiting blocks (21) are respectively installed on the lower side wall of the connecting plate (19) and on both sides of the rotating plate (20).

2. The tissue pulverizing device for genetic testing according to claim 1, characterized in that: The trough body (4) is a long strip structure, and both ends are arc-shaped structures.

3. The tissue pulverizing device for genetic testing according to claim 1, characterized in that: The plurality of groups of cutters (17) are arranged in a spiral shape outside the connecting sleeve (16), and the rotating plate (20) does not contact the cutters (17).

4. The tissue pulverizing device for genetic testing according to claim 1, characterized in that: A connecting block (10) is installed on the lower side of the moving block (9), a slideway (11) is provided on the L-shaped frame (2) for the connecting block (10) to slide through, a U-shaped connecting frame (12) is connected to the outer side of the connecting block (10) by means of bolts, a transverse plate (13) is installed on the lower side of the U-shaped connecting frame (12), and the motor (14) is fixedly installed on the lower side of the transverse plate (13).

5. The tissue pulverizing device for genetic testing according to claim 1, characterized in that: Support blocks (7) are respectively installed at both ends of the threaded shaft (6), and the lower side of the support block (7) is fixedly installed on the upper side of the L-shaped frame (2). A motor (8) for driving the threaded shaft (6) is installed on one group of the support blocks (7).

6. The tissue pulverizing device for genetic testing according to claim 1, characterized in that: A controller (18) is installed on the L-shaped frame (2), and the controller (18) is connected to the motor 1 (8) and the motor 2 (14) respectively through a wire.

7. The tissue pulverizing device for genetic testing according to claim 1, characterized in that: The slot cover (5) is provided with a second slideway (22) for the rotating shaft (15) to slide through.

8. The tissue pulverizing device for genetic testing according to claim 1, characterized in that: A support frame (3) is installed on the upper side of the base plate (1) and is adapted to fit into the trough body (4).