Thermotank for decellularized culture

By designing support components and moving wheels at the bottom of the constant temperature box, the problem of external vibration interfering with cell culture is solved, the stability and convenience of the constant temperature box are achieved, and the culture effect is improved.

CN223409647UActive Publication Date: 2025-10-03JIANGSU YOUCHUANG BIOMEDICAL TECH CO LTD
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Patent Information

Application Number
CN202422752971.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-12
Publication Date
2025-10-03
Estimated Expiration
2034-11-12

AI Technical Summary

Technical Problem

Existing incubators may interfere with cell culture due to external vibrations, leading to experimental failure or inaccurate data.

Method used

A constant temperature incubator for decellularization culture was designed. The bottom support assembly included a fixed plate, a sleeve column, a moving wheel, a bottom block and a damper. The damper and the bottom block cooperated to reduce vibration transmission, and the stability was improved by the design of the support frame and the placement table.

Benefits of technology

It reduces the shaking of the incubator, improves the installation stability, facilitates movement and transportation, enhances the culture effect, and protects cell samples from external vibration interference.

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Abstract

The utility model discloses a constant-temperature box for decellularized culture, and belongs to the field of constant-temperature boxes. The device mainly comprises a constant-temperature assembly, a plurality of supporting assemblies used for moving and supporting are fixedly installed at the bottom of the constant-temperature assembly, the constant-temperature assembly comprises a box body, each supporting assembly comprises a fixing piece, the fixing pieces are fixedly installed on the box body, the bottoms of the fixing pieces are rotationally connected with sleeve columns, and the sleeve columns are sleeved with the fixing pieces. The constant-temperature box for decellularization culture comprises a box body, the box body is provided with a sleeve column, the outer side of the sleeve column is fixedly provided with moving wheels for moving and a bottom block, the bottom block is arranged at the bottom of the sleeve column, the top of the bottom block is fixedly provided with a damper, and the bottom block can make contact with the ground. According to the constant-temperature box, the constant-temperature box can play a damping role through the bottom blocks, and the distance between the bottom blocks can be adjusted up and down through cooperative use of the rotating disc and the threaded rod, so that the constant-temperature box can be suitable for various conditions, and the mounting stability of the constant-temperature box can be further improved.
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Description

Technical Field

[0001] The present application relates to the technical field of constant temperature chambers, and in particular to a constant temperature chamber for decellularization culture. Background Art

[0002] Decellularized culture incubators are commonly referred to as cell culture incubators or cell culture incubators. These devices are designed specifically for cell culture and can provide stable temperature, humidity, and carbon dioxide concentration to simulate the environmental conditions of cells in the body to support cell growth and reproduction. In some special applications, decellularized culture may involve more environmental control requirements, such as regulating oxygen concentration to meet these needs;

[0003] However, in the incubator equipment we currently use, external vibrations may interfere with cell culture, especially for certain sensitive cell types or specific experimental conditions, which may lead to experimental failure or inaccurate data.

[0004] Therefore, it is necessary to provide a thermostat for decellularization culture to solve the above problems. Utility Model Content

[0005] Based on the above problems existing in the prior art, the problem to be solved by this application is: to provide a constant temperature box for decellularization culture, which can achieve the effect of supporting the bottom of the constant temperature box, thereby reducing the problem of large-scale shaking that may be caused by the constant temperature box during operation.

[0006] The technical solution adopted by the present application to solve the technical problem is: a thermostatic box for decellularization culture, including a thermostatic component, wherein a plurality of support components for movement and support are fixedly installed at the bottom of the thermostatic component, the thermostatic component includes a box body, and the support components include:

[0007] A fixing plate, the fixing plate is fixedly mounted on the box body, the bottom of the fixing plate is rotatably connected to a sleeve column, and a moving wheel for movement is fixedly mounted on the outer side of the sleeve column;

[0008] The bottom block is arranged at the bottom of the sleeve column, a damper is fixed on the top of the bottom block, the damper is located at the inner bottom of the sleeve column, and the bottom block can contact the ground.

[0009] Furthermore, a notch is provided on the sleeve column, a turntable is provided inside the sleeve column near the notch, a threaded rod is connected to the inner thread of the turntable, and the bottom of the threaded rod is fixedly connected to the damper.

[0010] Furthermore, a limiting groove is provided on the turntable, a fixing ring is fixedly installed on the inner wall of the sleeve, and several groups of limiting rods are fixedly installed on the bottom of the fixing ring. The bottom of the limiting rod can rotate inside the limiting groove, and the turntable can be rotated by the limiting rod, and the limiting rod is used to limit the turntable.

[0011] Furthermore, a plurality of relatively mounted support frames are fixedly mounted on the inner wall of the box, and a placement table is plugged into the support frame. The support frame is used to support the placement table, and the placement table can be used to place cell dishes that need to be cultured.

[0012] Furthermore, the ends of the support frame and the placement table are each provided with a fixing hole, and a pin is inserted into the fixing hole.

[0013] Furthermore, a sealing door is provided on the box body, and the sealing door is used to seal the box body.

[0014] Furthermore, the moving wheels can move synchronously through the sleeves, and the moving wheels can contact the ground.

[0015] The beneficial effects of this application are:

[0016] The present application provides a constant temperature incubator for decellularized culture, which is provided with a bottom block, so that the constant temperature incubator can play a shock-absorbing role through the bottom block, and through the cooperation between the turntable and the threaded rod, the distance of the bottom block can be adjusted up and down, so that the constant temperature incubator can be suitable for a variety of situations, thereby further improving the installation stability of the constant temperature incubator.

[0017] The present application provides a constant temperature incubator for decellularization culture, which is provided with movable wheels so that the entire constant temperature incubator is easy to move, thereby facilitating transportation. At the same time, several groups of support frames are provided inside the box, so that multiple groups of placement tables can be placed inside the box at the same time, thereby improving the culture effect of the constant temperature incubator. In addition, by providing pins, the placement tables can be fixed on the support frames, thereby preventing the placement tables from being unstable. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The drawings that constitute part of this application are used to provide a further understanding of this application. The illustrative embodiments of this application and their descriptions are used to explain this application and do not constitute an improper limitation on this application. In the drawings:

[0019] Figure 1 This is an overall schematic diagram of a constant temperature box for decellularization culture in this application;

[0020] Figure 2 This is a schematic diagram of the constant temperature component in 1;

[0021] Figure 3 This is a schematic diagram of the support assembly in 1;

[0022] Figure 4 Schematic diagram of the turntable of the three support components;

[0023] Figure 5 Schematic diagram of the limit slots of the three support components;

[0024] Among them, the reference numerals in the figures are:

[0025] 10. Constant temperature assembly; 11. Box body; 12. Sealed door; 13. Support frame; 14. Placement table; 15. Fixing hole; 16. Latch;

[0026] 20. Support assembly; 21. Fixed plate; 22. Moving wheel; 23. Sleeve column; 24. Notch; 25. Turntable; 26. Limiting groove; 27. Limiting rod; 28. Fixing ring; 29. ​​Threaded rod; 210. Damper; 211. Bottom block. DETAILED DESCRIPTION

[0027] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments in this application can be combined with each other. The present application will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0028] In order to enable those skilled in the art to better understand the present invention, the following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments in the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts should fall within the scope of protection of this application.

[0029] like Figure 1 As shown, the present application provides a constant temperature box for decellularization culture, including a constant temperature component 10, and a support component 20 fixedly installed at the bottom of the constant temperature component 10, wherein the constant temperature component 10 is used to culture cells in a controlled environment to ensure that the cells grow and differentiate under optimal conditions, wherein during the cell culture process, the constant temperature component 10 provides a stable temperature, humidity and CO2 concentration environment to simulate the growth conditions of cells in a living body, and the support component 20 is used to support the constant temperature component 10 as a whole, thereby ensuring the stability of the constant temperature component 10, and the support component 20 can also move the constant temperature component 10 as a whole, so that the constant temperature component 10 can be easily moved and repositioned.

[0030] like Figure 1 and Figure 2As shown, the constant temperature assembly 10 includes a box body 11, on the inner wall of which are fixedly mounted several groups of relatively mounted support frames 13, on which a placement table 14 is plugged, and the support frame 13 is used to support the placement table 14, and the placement table 14 can be used to place cell dishes, bottles or other culture containers that need to be cultured to ensure that they are fixed and placed during the culture process.

[0031] At the same time, fixing holes 15 are provided at the ends of the support frame 13 and the placement table 14, and pins 16 are inserted into the fixing holes 15. Therefore, after the placement table 14 is installed on the support frame 13, the two groups of fixing holes 15 will be aligned with each other, and the pins 16 pass through the two groups of fixing holes 15 respectively, so that the placement table 14 can be fixed on the support frame 13, thereby improving the stability of the placement table 14.

[0032] The box body 11 is provided with a sealed door 12, which is used to seal the box body 11, thereby ensuring that the cultured samples will not be affected by sudden changes in the outside world or adverse environmental conditions during the experiment. The sealed door 12 is provided with a perspective window, which is made of glass. The perspective window allows staff to check the samples without opening the sealed door 12, thereby reducing the chance of outside air or pollutants entering the constant temperature box and protecting the culture environment.

[0033] like Figure 1 As shown, the support assembly 20 includes a fixing plate 21, which is fixedly installed on the bottom of the box body 11. The bottom of the fixing plate 21 is rotatably connected to a sleeve column 23, and the outer side of the sleeve column 23 is fixedly installed with a moving wheel 22. The moving wheel 22 can contact the ground, so that when the box body 11 needs to be transported, it can be moved after the moving wheel 22 contacts the ground.

[0034] At the same time, a bottom block 211 is provided inside the sleeve column 23. The bottom block 211 can contact the ground, and the bottom block 211 can be a rubber elastic structure. After the bottom block 211 contacts the ground, the moving wheel 22 will be in the same position as the bottom block 211, so that the moving wheel 22 is blocked by the bottom block 211, and the moving wheel 22 will not move at will. Therefore, the bottom block 211 can support the box body 11 as a whole after contacting the ground, and can also play a certain shock-absorbing effect, thereby improving the stability of the box body 11.

[0035] A notch 24 is provided on the sleeve column 23, and a turntable 25 is provided inside the sleeve column 23 near the notch 24. A limiting groove 26 is provided on the turntable 25. At the same time, a fixing ring 28 is fixedly installed on the inner wall of the sleeve column 23, and several groups of limiting rods 27 are fixedly installed on the bottom of the fixing ring 28. The bottom of the limiting rod 27 can rotate inside the limiting groove 26, and the turntable 25 can be rotated by the limiting rod 27. The limiting rod 27 is used to limit the turntable 25.

[0036] The internal thread of the turntable 25 is connected to a threaded rod 29, and a damper 210 is fixedly installed at the bottom of the threaded rod 29, and the damper 210 is fixedly connected to the bottom block 211, so that the staff can contact the turntable 25 through the notch 24. When the turntable 25 is rotated, the threaded rod 29 can be adjusted up and down, so that the position of the bottom block 211 can be moved. By moving the position of the bottom block 211, the bottom block 211 can contact the uneven ground, and the movement of the bottom block 211 allows the box body 11 to be adapted to different environmental requirements. By providing the damper 210, the constant temperature component 10 can reduce the transmission of these vibrations to the constant temperature box, thereby protecting the cultured samples from interference from external vibrations.

[0037] The above description is merely a preferred embodiment of the present application and is not intended to limit the present application. Various modifications and variations are possible for those skilled in the art. Any modifications, equivalent substitutions, or improvements made within the spirit and principles of the present application shall be included within the scope of protection of the present application.

Claims

1. A thermostat for decellularized culture, comprising a thermostat component (10), characterized in that: Several groups of support assemblies (20) for movement and support are fixedly installed at the bottom of the thermostatic assembly (10). The thermostatic assembly (10) includes a box (11), and the support assembly (20) includes: A fixing plate (21), the fixing plate (21) is fixedly mounted on the box body (11), the bottom of the fixing plate (21) is rotatably connected to a sleeve column (23), and a moving wheel (22) for movement is fixedly mounted on the outer side of the sleeve column (23); A bottom block (211) is provided at the bottom of the sleeve column (23); a damper (210) is fixed on the top of the bottom block (211); the damper (210) is located at the inner bottom of the sleeve column (23); and the bottom block (211) is capable of contacting the ground.

2. The incubator for decellularization culture according to claim 1, characterized in that: A notch (24) is provided on the sleeve column (23), a turntable (25) is provided inside the sleeve column (23) near the notch (24), a threaded rod (29) is connected to the inner thread of the turntable (25), and the bottom of the threaded rod (29) is fixedly connected to the damper (210).

3. The incubator for decellularization culture according to claim 2, characterized in that: A limiting groove (26) is provided on the turntable (25); a fixing ring (28) is fixedly installed on the inner wall of the sleeve (23); a plurality of groups of limiting rods (27) are fixedly installed on the bottom of the fixing ring (28); the bottom of the limiting rod (27) can rotate inside the limiting groove (26); the turntable (25) can be rotated by the limiting rod (27); and the limiting rod (27) is used to limit the turntable (25).

4. The incubator for decellularization culture according to claim 3, characterized in that: Several groups of relatively mounted support frames (13) are fixedly mounted on the inner wall of the box (11), and a placement table (14) is plugged into the support frame (13). The support frame (13) is used to support the placement table (14), and the placement table (14) can be used to place cell dishes that need to be cultured.

5. The incubator for decellularization culture according to claim 4, characterized in that: The ends of the support frame (13) and the placement platform (14) are both provided with fixing holes (15), and the interiors of the fixing holes (15) are plugged with latches (16).

6. The incubator for decellularization culture according to claim 1, characterized in that: The box body (11) is provided with a sealing door (12), and the sealing door (12) is used to seal the box body (11).

7. The incubator for decellularization culture according to claim 1, characterized in that: The moving wheels (22) can move synchronously through the sleeves (23), and the moving wheels (22) can contact the ground.