Dual-channel optical detection device based on micro-fluidic chip

Abstract

The utility model discloses a micro-fluidic chip-based dual-channel optical detection device, which comprises a shell assembly, a fixed frame, an optical detection module and a movement mechanism, the fixed frame is arranged in the shell assembly, the movement mechanism is arranged in the shell assembly and is arranged on the fixed frame, the optical detection module is arranged in the shell assembly, and the movement mechanism is arranged on the fixed frame. The fluorescence detection device is high in instrument integration level, can be matched with different optical detection modules for fluorescence detection according to actual requirements of fluorescent dyes, is convenient and rapid, is high in practicability, adopts a micro-fluidic chip technology, can realize rapid detection of a plurality of samples in a small size, and is high in practicability. The problems that in the background technology, a high-definition camera photographing mode or a PMT detection module is adopted for signal collection, a multi-channel single-channel integrated detection device is also adopted for signal detection, the size of a common film is large, power consumption is large, and use of a small rapid diagnosis instrument is not facilitated are solved.

Description

TECHNICAL FIELD

[0001] The utility model belongs to optical detection device technical field, especially relate to a double -channel optical detection device based on micro -fluidic chip. BACKGROUND

[0002] PCR (polymerase chain reaction) technology is a kind of molecular biology technology in vitro detection amplification specific nucleic acid fragment sequence, because it has the characteristics of specificity, high sensitivity, fast, and is widely used in molecular biology detection and analysis.

[0003] The PCR instrument (nucleic acid amplification detector) used at present mainly adopts high-definition camera photographing mode or PMT detection module to carry out signal acquisition, and there is also multi-channel single-channel detection device for signal detection, and the volume is relatively large, the power consumption is relatively large, which is not conducive to the use of small and rapid diagnostic instrument.

[0004] Based on this, our company specially develops a double-channel optical detection device based on micro-fluidic chip, adopts double-channel optical detection device and micro-fluidic chip technology, rapidly detects multiple points on micro-fluidic chip, obtains multiple detection results in turn, and improves detection efficiency. Utility model content

[0005] The utility model aims at overcoming the problems in the prior art that high-definition camera photographing mode or PMT detection module is used for signal acquisition, and there is also multi-channel single-channel detection device for signal detection, the volume is relatively large, the power consumption is relatively large, which is not conducive to the use of small and rapid diagnostic instrument, provides a double-channel optical detection device based on micro-fluidic chip, which adopts double-channel optical detection device and micro-fluidic chip technology, rapidly detects multiple points on micro-fluidic chip, obtains multiple detection results in turn, and improves detection efficiency.

[0006] In order to realize the above-mentioned purpose, the utility model provides a double-channel optical detection device based on micro-fluidic chip, which comprises a shell assembly, a fixing frame, an optical detection module and a motion mechanism, the fixing frame is arranged in the shell assembly, the motion mechanism is arranged in the shell assembly and on the fixing frame, the optical detection module is arranged in the shell assembly, and the optical detection module is arranged on the motion mechanism.

[0007] Preferably, the fixing frame is provided with a circuit board structure, and the fixing frame is symmetrically provided with a photoelectric switch structure on the side close to the motion mechanism.

[0008] Preferably, the motion mechanism comprises a chip, a heat insulation tray, a motor base, a first synchronous pulley, a photoelectric baffle, a code disc, a adapter ring, a synchronous belt strip, a second synchronous pulley, a stepping motor, a rotating shaft, a heating film and a heat conduction plate, the motor base is fixedly arranged in the middle of the fixed frame, the stepping motor is arranged on the motor base, the rotating rod is rotatably arranged through the motor base, the second synchronous pulley is fixedly connected below the stepping motor and arranged below the motor base, the first synchronous pulley is fixedly sleeved on the rotating rod and arranged below the motor base, the synchronous belt strip is sleeved on the first synchronous pulley and the second synchronous pulley, the adapter ring is fixedly sleeved on the lower end of the rotating shaft, the code disc is fixedly sleeved on the lower end of the rotating shaft and arranged below the adapter ring, the photoelectric baffle is fixedly arranged on the adapter ring, the heat insulation tray is arranged above the rotating shaft, the heating film is arranged on the heat insulation tray, the heat conduction plate is arranged on the heating film, and the chip is arranged on the heat conduction plate.

[0009] Preferably, screw structures are uniformly arranged on the chip, and copper stud structures corresponding to the screw structures are rotatably arranged on the heat insulation tray.

[0010] Preferably, a flange bearing is sleeved at the connection between the rotating rod and the motor base.

[0011] Preferably, the photoelectric baffle and the code disc are arranged corresponding to the photoelectric switch structure on the fixed frame.

[0012] Preferably, the shell assembly comprises an upper cover, a display screen, an upper shell, a lower shell and a button, the lower shell is arranged below the fixed frame, the upper cover is arranged on the lower shell, the upper cover is arranged at the top center of the upper shell and above the chip, the display screen is arranged through the side wall of the upper shell, and the button is arranged through the side wall of the upper shell and on one side of the display screen.

[0013] The utility model discloses the beneficial effects are:

[0014] The utility model discloses instrument integration degree is high, can according to actual fluorescent dye's demand, and the different optical detection module of collocation is in fluorescent detection, convenient and fast and practicality is high, and adopt micro -fluidic chip technology, can realize multiple sample's rapid detection in small volume, solved the background technology in the mode of adoption high -definition camera photographing or PMT detection module and signal acquisition, also have multichannel single -channel set -up detection device and signal detection, the volume of general sheet is big, and power consumption is big, and it is not favorable for small -size rapid diagnostic instrument use's problem. BRIEF DESCRIPTION OF DRAWINGS

[0015] Figure 1 It is whole structure schematic diagram of the utility model discloses a kind of dual-channel optical detection device based on micro -fluidic chip.

[0016] Figure 2 This is a diagram of the internal structure of a dual-channel optical detection device based on a microfluidic chip in the utility model.

[0017] Figure 3 This is a structural diagram of a fixing mechanism in a dual-channel optical detection device based on a microfluidic chip in the utility model.

[0018] Figure 4 It is an exploded view of a fixing mechanism in a dual-channel optical detection device based on a microfluidic chip according to the present invention.

[0019] In the figure: 1. Shell assembly; 2. Fixing frame; 3. Optical detection module; 4. Motion mechanism; 5. Chip; 6. Heat insulation tray; 7. Motor seat; 8. First synchronous pulley; 9. Photoelectric baffle; 10. Code disk; 11. Adapter ring; 12. Synchronous belt; 13. Second synchronous pulley; 14. Stepper motor; 15. Rotating shaft; 16. Heating film; 17. Heat conduction plate; 18. Flange bearing; 19. Upper cover; 20. Display screen; 21. Upper shell; 22. Lower shell; 23. Button. DETAILED DESCRIPTION

[0020] The following is combined with Figures 1-4 The technical solutions in the embodiments of the present invention are clearly and completely described. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. All other embodiments derived by persons of ordinary skill in the art based on the embodiments of the present invention without creative effort shall fall within the scope of protection of the present invention.

[0021] In the description of the present invention, it should be understood that the terms "longitudinal", "transverse", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention, and do not indicate or imply that the device or element referred to must have a specific orientation, specific orientation structure and operation, and therefore cannot be understood as a limitation on the present invention.

[0022] This embodiment provides a dual-channel optical detection device based on a microfluidic chip, including a shell assembly 1, a fixing frame 2, an optical detection module 3 and a motion mechanism 4. The fixing frame 2 is arranged in the shell assembly 1, the motion mechanism 4 is arranged in the shell assembly 1 and on the fixing frame 2, the optical detection module 3 is arranged in the shell assembly 1, the optical detection module 3 is arranged on the motion mechanism 4, a circuit board structure is provided on the fixing frame 2, and a photoelectric switch structure is symmetrically provided on one side of the fixing frame 2 close to the motion mechanism 4.

[0023] In one embodiment, specifically, the motion mechanism 4 includes the chip 5, the heat insulation tray 6, the motor base 7, the first synchronous pulley 8, the photoelectric flag 9, the code disc 10, the adapter ring 11, the synchronous belt strip 12, the second synchronous pulley 13, the stepping motor 14, the rotating shaft 15, the heating film 16 and the heat conduction plate 17. The motor base 7 is fixedly arranged in the middle of the fixed frame 2. The stepping motor 14 is arranged on the motor base 7. The rotating rod is rotatably arranged through the motor base 7. The second synchronous pulley 13 is fixedly connected below the stepping motor 14 and arranged below the motor base 7. The first synchronous pulley 8 is fixedly sleeved on the rotating rod and arranged below the motor base 7. The synchronous belt strip 12 is sleeved on the first synchronous pulley 8 and the second synchronous pulley 13. The adapter ring 11 is fixedly sleeved on the lower end of the rotating shaft 15. The code disc 10 is fixedly sleeved on the lower end of the rotating shaft 15 and arranged below the adapter ring 11. The photoelectric flag 9 is fixedly arranged on the adapter ring 11. The heat insulation tray 6 is arranged above the rotating shaft 15. The heating film 16 is arranged on the heat insulation tray 6. The heat conduction plate is arranged on the heating film 16. The chip 5 is arranged on the heat conduction plate 17. The chip 5 is uniformly provided with screw structures. The heat insulation tray 6 is rotatably provided with copper stud structures corresponding to the screw structures. The chip 5, the heat conduction plate 17 and the heat insulation tray 6 are sequentially fixedly arranged through the screw structures and the copper stud structures. The flange bearing 18 is sleeved on the connection between the rotating rod and the motor base 7.

[0024] In one embodiment, specifically, the photoelectric flag 9 and the code disc 10 are arranged corresponding to the photoelectric switch structure on the fixed frame 2. The photoelectric flag 9 and the code disc 10 are rotated to sweep the photoelectric switch under the driving of the stepping motor 14. The photoelectric switch is matched to realize the reset and displacement of the motion mechanism 4.

[0025] In one embodiment, specifically, the shell assembly 1 includes the upper cover 19, the display screen 20, the upper shell 21, the lower shell 22 and the button 23. The lower shell 22 is arranged below the fixed frame 2. The upper cover 19 is arranged on the lower shell 22. The upper cover 19 is arranged at the top center of the upper shell 21 and above the chip 5. The display screen 20 is arranged through the sidewall of the upper shell 21. The button 23 is arranged through the sidewall of the upper shell 21 and on one side of the display screen 20.

[0026] In this embodiment, the working process of the double-channel optical detection device based on the microfluidic chip 5 is as follows: the stepping motor 14 is started. The stepping motor 14 drives the second synchronous pulley 13 and the rotating shaft 15 to rotate through the first synchronous pulley 8 and the synchronous belt strip 12, thereby driving the heat insulation tray, the chip 5, the photoelectric flag 9 and the code disc 10 to rotate, completing the detection. When the photoelectric flag 9 and the code disc 10 are rotated to sweep the photoelectric switch under the driving of the stepping motor 14, the photoelectric switch is matched to realize the reset and displacement of the motion mechanism 4.

[0027] The above is only an example and description of the structure of the utility model, and those skilled in the art can make various modifications or supplements to the described specific embodiments or replace them with similar ways, as long as they do not deviate from the structure of the utility model or exceed the scope defined by the present claims, which shall belong to the protection scope of the utility model.

Claims

1. A dual-channel optical detection device based on a microfluidic chip (5), characterized in that: The invention comprises a housing component (1), a fixing frame (2), an optical detection module (3) and a motion mechanism (4), wherein the fixing frame (2) is arranged in the housing component (1), the motion mechanism (4) is arranged in the housing component (1) and on the fixing frame (2), the optical detection module (3) is arranged in the housing component (1), and the optical detection module (3) is arranged on the motion mechanism (4).

2. The dual-channel optical detection device based on a microfluidic chip (5) according to claim 1 is characterized in that: A circuit board structure is provided on the fixing frame (2), and a photoelectric switch structure is symmetrically provided on one side of the fixing frame (2) close to the motion mechanism (4).

3. The dual-channel optical detection device based on a microfluidic chip (5) according to claim 1 is characterized in that: The motion mechanism (4) comprises a chip (5), a heat-insulating tray (6), a motor seat (7), a first synchronous pulley (8), a photoelectric baffle (9), a code disk (10), an adapter ring (11), a synchronous belt strip (12), a second synchronous pulley (13), a stepping motor (14), a rotating shaft (15), a heating film (16) and a heat-conducting plate (17); the motor seat (7) is fixedly arranged in the middle of the fixed frame (2); the stepping motor (14) is arranged on the motor seat (7); the rotating rod rotates through the motor seat (7); the second synchronous pulley (13) is fixedly connected to the bottom of the stepping motor (14) and is arranged under the motor seat (7); the first The synchronous pulley (8) is fixedly sleeved on the rotating rod and is arranged below the motor seat (7); the synchronous belt strip (12) is sleeved on the first synchronous pulley (8) and the second synchronous pulley (13); the adapter ring (11) is fixedly sleeved on the lower end of the rotating shaft (15); the code disk (10) is fixedly sleeved on the lower end of the rotating shaft (15) and is arranged below the adapter ring (11); the photoelectric baffle (9) is fixedly arranged on the adapter ring (11); the heat insulation tray (6) is arranged above the rotating shaft (15); the heating film (16) is arranged on the heat insulation tray (6); the heat conduction disk is arranged on the heating film (16); and the chip (5) is arranged on the heat conduction plate (17).

4. The dual-channel optical detection device based on a microfluidic chip (5) according to claim 3 is characterized in that: The chip (5) is evenly distributed with screw structures, and a copper stud structure corresponding to the screw structure is rotatably provided under the thermal insulation tray (6). The chip (5), the heat conducting plate (17) and the thermal insulation tray (6) are fixed in place in sequence by the screw structure and the copper stud structure.

5. The dual-channel optical detection device based on a microfluidic chip (5) according to claim 3 is characterized in that: A flange bearing (18) is sleeved at the connection between the rotating rod and the motor seat (7).

6. The dual-channel optical detection device based on a microfluidic chip (5) according to claim 3, characterized in that: The photoelectric baffle (9) and the code disk (10) are respectively arranged corresponding to the photoelectric switch structure on the fixing frame (2).

7. The dual-channel optical detection device based on a microfluidic chip (5) according to claim 3 is characterized in that: The housing assembly (1) comprises an upper cover (19), a display screen (20), an upper shell (21), a lower shell (22) and a button (23); the lower shell (22) is arranged under the fixing frame (2); the upper cover (19) is arranged on the lower shell (22); the upper cover (19) is arranged at the top center of the upper shell (21) and above the chip (5); the display screen (20) is provided through the side wall of the upper shell (21); the button (23) is provided through the side wall of the upper shell (21) and is provided on one side of the display screen (20).

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