High-frequency ultrasonic coining device for in-vivo cornea biomechanical measurement

By designing a high-frequency ultrasonic imprinting device, the gap in in vivo corneal biomechanical measurement was filled, enabling accurate measurement of corneal biomechanical properties and providing reference data for the diagnosis and treatment of ophthalmic diseases.

CN223453210UActive Publication Date: 2025-10-21BEIJING INST OF OPHTHALMOLOGY +1
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Patent Information

Application Number
CN202422362971.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-27
Publication Date
2025-10-21
Estimated Expiration
2034-09-27

AI Technical Summary

Technical Problem

Current technology lacks a measuring device that can accurately measure the biomechanical properties of the cornea in vivo, which affects the diagnosis and treatment of ophthalmic diseases.

Method used

Design a high-frequency ultrasonic imprinting device for in vivo corneal biomechanical measurement, including a base, a lifting platform, a cantilever, a drive mechanism, a mechanical sensor, an ultrasonic transducer, and an imprinting test head. The lifting platform and drive mechanism control the imprinting test head to approach or move away from the eyeball, the ultrasonic transducer transmits ultrasonic waves and pressure, and the mechanical sensor detects external pressure.

Benefits of technology

It enables accurate measurement of in vivo corneal biomechanical properties, providing reference data for the diagnosis and treatment of ophthalmic diseases.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to a high-frequency ultrasonic coining device for in-vivo cornea biomechanical measurement. The high-frequency ultrasonic coining device comprises a base, a lifting platform, a cantilever, a driving mechanism, a mechanical sensor, an ultrasonic transducer and a coining testing head, a lifting platform is arranged on the base, the output end of the lifting platform is connected with one end of a cantilever, a driving mechanism is mounted at the other end of the cantilever, a mechanical sensor is mounted on the driving mechanism, an ultrasonic transducer is mounted at the detection end of the mechanical sensor, and a coining test head is mounted at the output end of the ultrasonic transducer. According to the high-frequency ultrasonic coining device for in-vivo cornea biomechanical measurement, the coining testing head is aligned with the center of the cornea of a patient through the lifting table, the driving mechanism drives the coining testing head to coining the eyeball of the patient, and the ultrasonic transducer transmits ultrasonic waves and pressure to the cornea of the patient through the coining testing head and detects echo data; the mechanical sensor detects data of external pressure borne by eyeballs of a patient, and therefore reference data are provided for diagnosis and treatment of ophthalmic diseases.
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Description

TECHNICAL FIELD

[0001] The utility model relates to corneal biomechanics measuring device technical field, especially in the body corneal biomechanics measuring with high frequency ultrasonic printing pressure device. BACKGROUND

[0002] The human cornea refers to the transparent part of the outer layer of the eyeball wall, which is circular, occupies one sixth of the outer layer area, is about 1mm thick, is mainly composed of avascular connective tissue, is curved like a spherical surface, and has a refractive effect. This means that a small change in the shape of the cornea will lead to a significant change in the optical properties of the cornea. The biomechanical properties of the cornea play an important role in maintaining the shape and transparency of the cornea, designing refractive surgery, and developing artificial corneas, but there is still no measuring device on the market that can accurately measure the biomechanical indicators such as elasticity and strength of in vivo corneal tissue.

[0003] Therefore, there is an urgent need to provide a high-frequency ultrasonic printing pressure device for in vivo corneal biomechanics measurement. UTILITY MODEL CONTENT

[0004] (I) Technical problem to be solved

[0005] In view of the above-mentioned shortcomings and deficiencies of the prior art, the utility model provides a high-frequency ultrasonic printing pressure device for in vivo corneal biomechanics measurement to measure the biomechanical properties of in vivo cornea, thereby providing a reference for the diagnosis and treatment of ophthalmic diseases.

[0006] (II) Technical scheme

[0007] In order to achieve the above-mentioned purpose, the utility model adopts the main technical scheme including:

[0008] The utility model embodiment provides a high-frequency ultrasonic printing pressure device for in vivo corneal biomechanics measurement, which comprises a base, a lifting platform, a cantilever, a driving mechanism, a mechanical sensor, an ultrasonic transducer and a printing test head.

[0009] The lifting platform is arranged on the base, the output end of the lifting platform is connected with one end of the cantilever, the other end of the cantilever is installed with the driving mechanism, the mechanical sensor is installed on the driving mechanism, the detection end of the mechanical sensor is installed with the ultrasonic transducer, the working frequency of the ultrasonic transducer is 1-50MHz, and the output end of the ultrasonic transducer is installed with the printing test head.

[0010] The lifting platform can drive the cantilever, the driving mechanism, the ultrasonic transducer and the indentation testing head to ascend or descend, the driving mechanism can drive the ultrasonic transducer and the indentation testing head to move to approach or move away from the eyeball of the patient, so that the indentation testing head indents the eyeball of the patient, the ultrasonic transducer can transmit ultrasonic waves and pressure to the cornea of the patient through the indentation testing head, and detect echo data, and the mechanical sensor can detect external pressure received by the eyeball of the patient.

[0011] Optionally, the computer is further connected with the lifting platform, the driving mechanism, the mechanical sensor and the ultrasonic transducer.

[0012] Optionally, the computer is further connected with the lifting platform, the driving mechanism, the mechanical sensor and the ultrasonic transducer.

[0013] Optionally, the driving mechanism comprises a displacement platform, a sliding groove guide rail assembly and a linear stepping motor connected with the computer.

[0014] The body of the linear stepping motor is mounted on the cantilever, the output end of the linear stepping motor is in driving connection with the displacement platform, the bottom of the displacement platform is slidably arranged on the cantilever through the sliding groove guide rail assembly, and the upper part of the displacement platform is mounted with the mechanical sensor, the ultrasonic transducer and the indentation testing head.

[0015] Optionally, the computer is further connected with the lifting platform, the driving mechanism, the mechanical sensor and the ultrasonic transducer.

[0016] The bottom of the end of the cantilever away from the lifting platform is provided with the camera mounting plate, the CCD camera and the optical lens are mounted on the camera mounting plate, and the CCD camera and the optical lens are directed to the area where the indentation testing head is located.

[0017] Optionally, the periphery of the cantilever, the driving mechanism, the ultrasonic transducer and the camera mounting plate is provided with an outer shell, the outer shell is provided with a through hole corresponding to the area of the indentation testing head, the through hole is provided with a video acquisition window below the through hole.

[0018] Optionally, the diameter of the indentation testing head is 1-3mm, and different sizes of indentation testing heads can be replaced according to the test requirements.

[0019] (Three) beneficial effects

[0020] The utility model discloses an advantageous effect is: the utility model discloses in vivo corneal biomechanics measurement uses high frequency ultrasonic imprinting device, because in vivo corneal biomechanics measurement uses high frequency ultrasonic imprinting device, including base, lifting platform, cantilever, drive mechanism, mechanics sensor, ultrasonic transducer and imprinting test head, lifting platform is set up on the base, and the output of lifting platform is connected with one end of cantilever, and the other end of cantilever installs drive mechanism, and drive mechanism installs mechanics sensor, and the detection end of mechanics sensor installs ultrasonic transducer, and the output of ultrasonic transducer installs imprinting test head, lifting platform can drive cantilever, drive mechanism, ultrasonic transducer and imprinting test head and rise or drop, and drive mechanism can drive ultrasonic transducer and imprinting test head and move to approach or away from patient's eyeball, so that imprinting test head imprints the eyeball of patient, and ultrasonic transducer can pass through imprinting test head and transmit ultrasonic wave and pressure to the cornea of patient, and detect echo data, and mechanics sensor can detect the external pressure that the eyeball of patient has received, relative to prior art, it can drive imprinting test head to rise or drop through lifting platform, and is aligned with the patient's eye corneal center, and drive mechanism drives imprinting test head and imprints the eyeball of patient, and ultrasonic transducer transmits ultrasonic wave and pressure to the cornea of patient through imprinting test head, and detects echo data, and mechanics sensor detects the external pressure data that the eyeball of patient has received, to provide reference data for the diagnosis and treatment of ophthalmic disease. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 It is the stereogram schematic drawing of in vivo corneal biomechanics measurement use high frequency ultrasonic imprinting device of the utility model;

[0022] Figure 2 It is the internal structure schematic drawing of in vivo corneal biomechanics measurement use high frequency ultrasonic imprinting device of the utility model;

[0023] Figure 3 It is the stereogram schematic drawing of in vivo corneal biomechanics measurement use high frequency ultrasonic imprinting device at cantilever of the utility model.

[0024]

Explanation of Mark

[0025] 1: base;2: lifting platform;3: cantilever;4: drive mechanism;5: mechanics sensor;6, ultrasonic transducer;7: imprinting test head;9: displacement platform;10: sliding slot guide rail assembly;11: linear stepper motor;12: camera mounting plate;13: CCD camera;14: optical lens;15: shell;16: video acquisition window. DETAILED DESCRIPTION

[0026] In order to better explain the utility model, in order to facilitate understanding, the utility model is described in detail below in combination with the drawings through specific embodiments.

[0027] With reference to Figure 1 , Figure 2 and Figure 3 , the embodiment provides a high-frequency ultrasonic indentation device for in vivo corneal biomechanical measurement, comprising a base 1, a lifting platform 2, a cantilever 3, a driving mechanism 4, a mechanical sensor 5, an ultrasonic transducer 6 and an indentation test head 7.

[0028] The lifting platform 2 is arranged on the base 1, the output end of the lifting platform 2 is connected with one end of the cantilever 3, the other end of the cantilever 3 is installed with the driving mechanism 4, the driving mechanism 4 is installed with the mechanical sensor 5, the detection end of the mechanical sensor 5 is installed with the ultrasonic transducer 6, the working frequency of the ultrasonic transducer is 1-50 MHz, and the output end of the ultrasonic transducer 6 is installed with the indentation test head 7.

[0029] The lifting platform 2 can drive the cantilever 3, the driving mechanism 4, the ultrasonic transducer 6 and the indentation test head 7 to ascend or descend, the driving mechanism 4 can drive the ultrasonic transducer 6 and the indentation test head 7 to move to approach or move away from the eyeball of the patient, so that the indentation test head 7 indents the eyeball of the patient, the ultrasonic transducer 6 can transmit ultrasonic waves and pressure to the cornea of the patient through the indentation test head 7 and detect echo data, and the mechanical sensor 5 can detect the external pressure received by the eyeball of the patient.

[0030] It should be noted that the indentation refers to that the front end of the indentation test head 7 contacts the eyeball of the patient and exerts pressure on the cornea on the eyeball of the patient, so that the cornea on the eyeball of the patient is slightly deformed. In addition, since the force is mutual, when the indentation test head 7 indents the cornea on the eyeball of the patient, the external pressure received by the eyeball of the patient is equal in size and opposite in direction to the resistance of the cornea on the eyeball of the patient to the indentation test head 7, and the resistance of the cornea on the eyeball of the patient to the indentation test head 7 is transmitted to the detection end of the mechanical sensor 5 through the ultrasonic transducer 6, so that the mechanical sensor 5 can indirectly measure the external pressure received by the eyeball of the patient.

[0031] Further, the diameter of the indentation test head 7 is 1-3 mm, the indentation depth is 1-3 mm, and the indentation speed is 20-150 mm / min. Different sizes of the indentation test head can be replaced according to the test needs. It should be noted that the driving mechanism 4 drives the ultrasonic transducer 6, thereby realizing control of the indentation depth, the indentation speed and the indentation measurement time of the indentation test head 7.

[0032] In the embodiment, the frequency of the ultrasonic transducer 6 generating ultrasonic waves is 10 Mhz, the pulse repetition frequency is 1K, the pulse amplitude is 400V, the gain is 60dB, and the bandwidth is 1K-30Mhz.

[0033] In the embodiment, the mechanical range of the mechanical sensor 5 is less than 10N.

[0034] In the embodiment, the high-frequency ultrasonic indentation device for in vivo corneal biomechanical measurement further comprises a computer, which is electrically connected with the lifting table 2, the driving mechanism 4, the mechanical sensor 5 and the ultrasonic transducer 6 respectively, so as to control the cooperation of the components.

[0035] Further, the computer is provided with a data collector which is electrically connected with the mechanical sensor 5 and the ultrasonic transducer 6 respectively, and the sampling rate of the data collector is 80-120 MS / s and the sampling accuracy is 8-12 bit. The purpose of setting the data collector is to synchronously collect the echo data detected by the ultrasonic transducer 6 and the mechanical data detected by the mechanical sensor 5.

[0036] It should be noted that the ultrasonic transducer 6 is used to detect the echo data on the eyeball of the patient, the mechanical sensor 5 is used to detect the external pressure on the eyeball of the patient, and the echo data and the external pressure data are transmitted to the computer, which all belong to the inherent performance of the ultrasonic transducer 6 and the mechanical sensor 5 as conventional existing devices, and the inherent performance of the ultrasonic transducer 6 and the mechanical sensor 5 is only used to detect and return data in the utility model, and the data is not analyzed and processed.

[0037] In the embodiment, the driving mechanism 4 comprises a displacement platform 9, a sliding groove guide rail assembly 10 and a linear stepping motor 11 which is electrically connected with the computer. The body of the linear stepping motor 11 is installed on the cantilever 3, the output end of the linear stepping motor 11 is in driving connection with the displacement platform 9, the bottom of the displacement platform 9 is slidably arranged on the cantilever 3 through the sliding groove guide rail assembly 10, and the upper part of the displacement platform 9 is installed with the mechanical sensor 5, the ultrasonic transducer 6 and the indentation test head 7.

[0038] In use, the linear stepping motor 11 can drive the displacement platform 9 to move, and the displacement platform 9 drives the mechanical sensor 5, the ultrasonic transducer 6 and the indentation test head 7 to do linear reciprocating motion, so as to approach or move away from the eyeball of the patient.

[0039] In the embodiment, the high-frequency ultrasonic indentation device for in vivo corneal biomechanical measurement further comprises a camera mounting plate 12, an optical lens 14 and a CCD camera 13 which is electrically connected with the computer.

[0040] The camera mounting plate 12 is arranged at the bottom of the end of the cantilever 3 away from the lifting table 2, the CCD camera 13 and the optical lens 14 are installed on the camera mounting plate 12, and the CCD camera 13 and the optical lens 14 are directed to the area where the indentation test head 7 is located. It should be noted that the CCD camera 1 is the abbreviation of Charge Coupled Device (charge coupled device), which is a kind of semiconductor imaging device, so it has the advantages of high sensitivity, strong light resistance, small distortion, small size, long service life, shock resistance and the like.

[0041] In use, the impression testing head 7 and the image of the eyeball of the patient pass through the optical lens 14 to the CCD camera 13, the CCD camera 13 collects the eyeball position data of the patient and sends the data to the computer, the computer controls the lifting platform 2 according to the eyeball position data of the patient, the lifting platform 2 drives the cantilever 3, the ultrasonic transducer 6 and the impression testing head 7 to ascend or descend, so that the impression testing head 7 is opposite to the center of the cornea of the eyeball of the patient.

[0042] In the embodiment, a shell 15 is arranged on the periphery of the cantilever 3, the driving mechanism 4, the mechanical sensor 5, the ultrasonic transducer 6, the impression testing head 7 and the camera mounting plate 12, the shell 15 is provided with a through hole corresponding to the area of the impression testing head 7, the impression testing head 7 passes through the through hole, and a video acquisition window 16 is further arranged on the shell 15 below the through hole. The shell 15 is arranged to protect the driving mechanism 4, the mechanical sensor 5, the ultrasonic transducer 6 and the impression testing head 7.

[0043] In the description of the utility model, it is to be understood that the terms "first", "second" are only for the purpose of description, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features limited by "first", "second" can be explicitly or implicitly included one or more of the features. In the description of the utility model, the meaning of "multiple" is two or more than two, unless otherwise specifically limited.

[0044] In the utility model, unless otherwise specifically defined and limited, the terms "installation", "connection", "connection", "fixing" and the like should be understood in a broad sense, for example, it can be fixed connection, or detachable connection, or integrated; it can be mechanical connection, or electrical connection; it can be directly connected, or indirectly connected through intermediate medium; it can be the communication between two elements or the interaction relationship between two elements. For ordinary skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific situation.

[0045] In the utility model, unless otherwise specifically defined and limited, the first feature is "on" or "under" the second feature, which can be direct contact between the first and second features, or indirect contact between the first and second features through intermediate medium. Moreover, the first feature is "above", "above" and "above" the second feature, which can be directly above or obliquely above the first feature, or only indicates that the height of the first feature is higher than that of the second feature. The first feature is "below", "below" and "below" the second feature, which can be directly below or obliquely below the first feature, or only indicates that the horizontal height of the first feature is lower than that of the second feature.

[0046] In the description of the present specification, the description of the terms "one embodiment", "some embodiments", "embodiment", "example", "specific example" or "some examples" and the like means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present application. In the present specification, the illustrative description of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any appropriate manner in any one or more embodiments or examples. Furthermore, the person skilled in the art can combine and combine the different embodiments or examples described in the present specification and the features of the different embodiments or examples without contradiction.

[0047] Although the embodiments of the present application have been shown and described above, it is understood that the above embodiments are exemplary and cannot be understood as limiting the present application, and the person skilled in the art can modify, modify, replace and modify the above embodiments within the scope of the present application.

Claims

1. A high-frequency ultrasonic indentation device for in vivo corneal biomechanical measurement, characterized by: The base (1), the lifting platform (2), the cantilever (3), the driving mechanism (4), the mechanical sensor (5), the ultrasonic transducer (6) and the indentation testing head (7) are arranged in sequence. The base (1) is provided with the lifting platform (2), the output end of the lifting platform (2) is connected with one end of the cantilever (3), the other end of the cantilever (3) is provided with the driving mechanism (4), the driving mechanism (4) is provided with the mechanical sensor (5), the detection end of the mechanical sensor (5) is provided with the ultrasonic transducer (6), and the output end of the ultrasonic transducer (6) is provided with the indentation testing head (7). The lifting platform (2) can drive the cantilever (3), the driving mechanism (4), the ultrasonic transducer (6) and the indentation testing head (7) to ascend or descend, the driving mechanism (4) can drive the ultrasonic transducer (6) and the indentation testing head (7) to move to approach or move away from the eyeball of the patient, so that the indentation testing head (7) indents the eyeball of the patient, the ultrasonic transducer (6) can transmit ultrasonic waves and pressure to the cornea of the patient through the indentation testing head (7), and detect echo data, and the mechanical sensor (5) can detect the external pressure received by the eyeball of the patient.

2. The high-frequency ultrasonic indentation device for corneal biomechanical measurement in vivo according to claim 1, wherein: The computer is electrically connected with the lifting platform (2), the driving mechanism (4), the mechanical sensor (5) and the ultrasonic transducer (6) respectively.

3. The high-frequency ultrasonic indentation device for corneal biomechanical measurement in vivo according to claim 2, wherein: The computer is provided with a data collector electrically connected with the mechanical sensor (5) and the ultrasonic transducer (6) respectively.

4. The high-frequency ultrasonic indentation device for corneal biomechanical measurement in vivo according to claim 2, wherein: The driving mechanism (4) comprises a displacement platform (9), a sliding groove guide rail assembly (10) and a linear stepping motor (11) electrically connected with the computer. The body of the linear stepping motor (11) is arranged on the cantilever (3), the output end of the linear stepping motor (11) is in driving connection with the displacement platform (9), the bottom of the displacement platform (9) is slidably arranged on the cantilever (3) through the sliding groove guide rail assembly (10), and the upper part of the displacement platform (9) is provided with the mechanical sensor (5), the ultrasonic transducer (6) and the indentation testing head (7).

5. The high-frequency ultrasonic indentation device for corneal biomechanical measurement in vivo according to claim 2, wherein: The camera mounting plate (12), the optical lens (14) and the CCD camera (13) electrically connected with the computer are further arranged. The camera mounting plate (12) is arranged at the bottom of the end of the cantilever (3) away from the lifting platform (2), the CCD camera (13) and the optical lens (14) are arranged on the camera mounting plate (12), and the CCD camera (13) and the optical lens (14) are directed to the area where the indentation testing head (7) is located.

6. The high-frequency ultrasonic indentation device for corneal biomechanical measurement in vivo according to claim 5, wherein: The shell (15) is arranged on the periphery of the cantilever (3), the driving mechanism (4), the ultrasonic transducer (6) and the camera mounting plate (12), the shell (15) is provided with a through hole corresponding to the area of the indentation testing head (7), the indentation testing head (7) passes through the through hole, and a video acquisition window (16) is further arranged on the shell (15) below the through hole.

7. The high-frequency ultrasonic indentation device for biomechanical measurement of the cornea in vivo according to any one of claims 1 to 6, characterized in that: The diameter of the indentation testing head (7) is 1-3mm.