Temperature control device and reactor
By designing a temperature control device in the bioreactor, utilizing refrigeration and heating components to control the temperature, and installing a silencer on the inlet pipe, the problems of temperature overshoot and excessively high pressure of the heat transfer medium were solved, thus achieving stable operation of the equipment and protection of the products.
Patent Information
- Application Number
- CN202422780738.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-14
- Publication Date
- 2025-10-21
- Estimated Expiration
- 2034-11-14
AI Technical Summary
Existing bioreactor temperature control devices suffer from problems such as temperature overshoot leading to product deactivation and excessively high pressure of the heat transfer medium causing damage to electrical components.
A temperature control device was designed, including a shell, a water tank, a refrigeration component, a heating component, and a heat transfer medium circulation component. The temperature range is controlled by reasonably adjusting the working state of the refrigeration and heating components, and a porous silencer is installed on the inlet pipe to reduce the circulation pressure.
It effectively avoids temperature overshoot, protects the product from deactivation, and prevents the overflow of heat transfer medium from damaging electrical components, ensuring stable equipment operation.
Smart Images

Figure CN223458329U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to a kind of temperature control device and reactor. BACKGROUND
[0002] Biological medicine exists biological fermentation stage in the production process;In the stage, raw materials are placed in biological reactor, the outside of reactor is jacket, and biological stock solution precision temperature control is realized by circulating temperature control medium in the jacket. Currently, temperature control unit is used to precisely control the temperature of harvested stock solution, but the current temperature control unit has use problems.
[0003] 1. Temperature overshoot problem, when the temperature control system heats the product inside the biological reactor, over-temperature situation is prone to occur, and high temperature can easily lead to product inactivation;
[0004] 2. After the heat transfer medium is circulated from the reaction vessel and returned to the water tank, sometimes due to the height difference, the heat transfer medium returned to the water tank has high pressure and is prone to be pumped out of the water tank, causing damage to electrical components.
[0005] Therefore, a temperature control device and reactor are proposed to solve the above problems. INVENTION CONTENTS
[0006] The utility model aims at overcoming the defects of the prior art and providing a temperature control device and reactor, which can well control over-temperature situation and avoid damage to electrical components caused by heat transfer medium overflow.
[0007] The technical scheme for achieving the above-mentioned object is: a temperature control device, comprising a shell, a water tank, a refrigeration assembly, a heating assembly and a heat transfer medium circulation assembly.
[0008] The water tank is arranged inside the shell, the refrigeration assembly is connected to the inner side of the water tank for cooling the heat transfer medium in the water tank, the heating assembly is connected to the inner side of the water tank for heating the heat transfer medium in the water tank, and the heat transfer medium circulation assembly is connected to the inner side of the water tank for transporting and recycling the heat transfer medium in the water tank.
[0009] Preferably, the refrigeration assembly comprises an evaporator, a compressor, a condenser and an expansion valve, the evaporator is arranged in the water tank, the evaporator is connected to the compressor, the compressor is connected to the condenser, the condenser is connected to the expansion valve, and the expansion valve is connected to the evaporator.
[0010] An oil separator is connected to the connecting pipeline between the compressor and the condenser;The condenser is also connected to a liquid injection valve, and the other end of the liquid injection valve is communicated with the connecting pipeline between the evaporator and the compressor.
[0011] Preferably, the heating assembly comprises an electric heater, which is arranged inside the water tank.
[0012] Preferably, the heat-conducting medium circulating assembly comprises a circulating pump, which is arranged inside the water tank, and the outlet end of the circulating pump is connected with an outlet pipe, and the inlet end is connected with an inlet pipe, and a pressure relief valve is arranged on the outlet pipe and the inlet pipe.
[0013] Preferably, the water tank is connected with a drain pipe.
[0014] Preferably, a pressure gauge and a temperature probe are arranged on the outlet pipe.
[0015] Preferably, a porous silencer is connected with the inlet pipe.
[0016] Preferably, a liquid level meter is further connected with the water tank.
[0017] A reactor based on a temperature control device comprises a reactor body and a circulating medium storage container, a jacket is arranged outside the reactor body, the inlet of the jacket is connected with the outlet pipe through a first liquid conveying pipe; the outlet of the jacket is connected with the inlet pipe through a second liquid conveying pipe; and the circulating medium storage container is connected with the liquid supplementing opening of the water tank through a third liquid conveying pipe.
[0018] The temperature control device can control the over-temperature condition by reasonable adjustment. The porous silencer connected with the inlet pipe can reduce the circulating pressure and avoid damage of electric components caused by overflow of the heat-conducting medium. BRIEF DESCRIPTION OF DRAWINGS
[0019] Figure 1 is the perspective view of the temperature control device of the utility model;
[0020] Figure 2 is the side view of the temperature control device of the utility model;
[0021] Figure 3 is the sectional view of the temperature control device of the utility model;
[0022] Figure 4 is the component connection frame diagram of the temperature control device of the utility model;
[0023] Figure 5 is the logic diagram of the temperature control device of the utility model;
[0024] Figure 6 is the detail view of the porous silencer of the utility model;
[0025] Figure 7 Figure 1 is a schematic diagram of the reactor of the present application.
[0026] Figure 1 is a schematic diagram of the reactor of the present application. DETAILED DESCRIPTION
[0027] The technical solutions of the present application will be described clearly and completely below in conjunction with the drawings. In the description of the present application, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" and the like indicate the orientation or positional relationship shown in the drawings, and are only used for the purpose of facilitating the description of the present application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be understood as limiting the present application. In addition, the terms "first", "second", "third" are only used for the purpose of description, and should not be understood as indicating or implying the importance of the opposite.
[0028] The present application will be further described below in conjunction with the drawings.
[0029] As shown in Figures 1-6 A temperature control device includes a housing 1, a water tank 2, a refrigeration assembly, a heating assembly, and a heat-conducting medium circulation assembly. The water tank 2 is arranged inside the housing 1, the refrigeration assembly is connected to the inner side of the water tank 2 for cooling the heat-conducting medium inside the water tank 2, the heating assembly is connected to the inner side of the water tank 2 for heating the heat-conducting medium inside the water tank 2, and the heat-conducting medium circulation assembly is connected to the inner side of the water tank 2 for transporting and recycling the heat-conducting medium inside the water tank 2.
[0030] As shown in Figure 3 The water tank 2 is connected with a drain pipe 14. The highest position of the drain pipe 14 defines the maximum amount of heat-conducting medium in the water tank 2.
[0031] As shown in Figure 3As shown, the water tank 2 is also connected with a liquid level gauge 24. The liquid level gauge sets four limit alarms: high-high liquid level alarm (to prevent too much heat conducting medium in the water tank 2 from overflowing, the vertical internal heat conducting medium reaches this position, the circulating pump 10 needs to stop running), high liquid level alarm (the heat conducting medium in the water tank 2 is enough, adding heat conducting medium can cause water to overflow, at this stage the circulating pump 10 can continue to run); low liquid level alarm (the heat conducting medium is higher than the heating end of the electric heater 9, the electric heater 9 will not be empty burning; at this time the circulating pump 10 can run normally); low-low liquid level alarm (the heat conducting medium is lower than the heating end of the electric heater 9, the electric heater 9 is empty burning, the electric heater 9 and the circulating pump 10 stop running).
[0032] As shown in Figure 3 , 4 , the refrigeration assembly includes an evaporator 3, a compressor 4, a condenser 5 and an expansion valve 6, the evaporator 3 is arranged in the water tank 2, the evaporator 3 is connected with the compressor 4, the compressor 4 is connected with the condenser 5, the condenser 5 is connected with the expansion valve 6, and the expansion valve 6 is connected with the evaporator 3; the compressor 4 is connected with an oil separator 7 on the connecting pipeline of the compressor 4 and the condenser 5; the condenser 5 is also connected with a liquid injection valve 8, and the other end of the liquid injection valve 8 communicates with the connecting pipeline of the evaporator 3 and the compressor 4.
[0033] Specifically, when the exhaust temperature of the compressor 4 is too high, the liquid injection valve 8 will control the opening degree according to the exhaust temperature. The opening and closing of the liquid injection valve 8 is controlled by two temperatures, and the opening temperature of the liquid injection valve 8 is slightly higher than the closing temperature of the liquid injection valve 8.
[0034] Specifically, the liquid injection valve 8 realizes opening and closing and adjustment according to the exhaust temperature of the compressor 4. When the exhaust temperature is higher than the opening temperature of the liquid injection valve 8, the liquid injection valve 8 is opened and the opening degree gradually increases with the temperature rising until the temperature is suppressed; when the outlet temperature reaches the closing temperature of the liquid injection valve 8, the liquid injection valve 8 is closed. In order to ensure the stability of the equipment and avoid the overheating of the compressor 4 leading to the stop of the compressor 4, the closing temperature of the liquid injection valve 8 is lower than the opening temperature of the liquid injection valve 8, and the temperature difference is about 10 degrees.
[0035] Specifically, the heating assembly includes an electric heater 9 arranged in the water tank 2. The electric heater 9 is used for heating the heat conducting medium in the water tank 2.
[0036] Specifically, the heat conducting medium circulating assembly includes a circulating pump 10 arranged in the water tank 2, the outlet end of the circulating pump 10 is connected with an outlet pipe 11, the inlet end is connected with an inlet pipe 12, and a pressure relief valve 13 is connected on the outlet pipe 11 and the inlet pipe 12. The pressure relief valve 13 is used for adjusting the circulating pressure. A pressure gauge 15 and a temperature probe 16 are arranged on the outlet pipe 11. The inlet pipe 12 is connected with a porous silencer 17. The porous silencer 17 is used for reducing the backwater pressure.
[0037] Specifically, after the target temperature setting is completed, the circulating pump 10 operates, the temperature probe 16 detects the heat conducting medium, the detected data is compared with the set temperature, when the actual temperature of the heat conducting medium is higher than the set temperature, the compressor 4 is started, and the expansion valve 6 is opened; when the temperature of the heat conducting medium is within a temperature difference range of 1 degree from the set temperature, the opening degree of the expansion valve 6 is gradually reduced, and the electric heater 9 is gradually started to avoid temperature overshoot.
[0038] Specifically, when the actual temperature of the heat conducting medium is lower than the set temperature, the electric heater 9 is started, and the heating amount is controlled according to the current pulse; when the temperature of the heat conducting medium is within a temperature difference range of 1 degree from the set temperature, the compressor 4 is started, and the expansion valve 6 is opened according to the minimum opening degree to avoid temperature overshoot.
[0039] Specifically, in the constant temperature stage, the compressor 4 and the expansion valve 6 are started, and the electric heater 9 is started according to the minimum pulse number; and the temperature is kept constant in the set range according to the adjustment of the external heat source parameters.
[0040] The temperature control device, by setting the refrigeration assembly connected to the inside of the water tank 2, is used for cooling the heat conducting medium in the water tank 2; the heating assembly is connected to the inside of the water tank 2, which is used for heating the heat conducting medium in the water tank 2; the heat conducting medium circulation assembly is connected to the inside of the water tank 2, which is used for transporting and recycling the heat conducting medium in the water tank 2. By reasonable adjustment, the over-temperature situation can be controlled. And connect the multi-hole silencer 17 on the inlet pipe 12, which can reduce the circulating pressure and avoid the damage of the electrical components caused by the overflow of the heat conducting medium.
[0041] As shown in Figure 7 A reactor based on a temperature control device, comprising a reactor body 18 and a circulating medium storage container 22, a jacket 19 is arranged outside the reactor body 18, the inlet of the jacket 19 is connected to the outlet pipe 11 through a first liquid conveying pipe 20; the outlet of the jacket 19 is connected to the inlet pipe 12 through a second liquid conveying pipe 21; the circulating medium storage container 22 is connected to the liquid supplementing port of the water tank 2 through a third liquid conveying pipe 23.
[0042] Specifically, first, the outlet pipe 11 and the inlet pipe 12 of the water tank 2 are connected to the inlet and outlet of the jacket 19 through the first liquid conveying pipe 20 and the second liquid conveying pipe 21, and the drain pipe 14 of the water tank 2 is connected to the drain port; the liquid supplementing port of the water tank 2 is connected to the circulating medium storage container 22 through the third liquid conveying pipe 23 to supplement the heat conducting medium in the water tank 2; set the target temperature, start circulating the heat conducting medium in the jacket 19; when the added heat conducting medium inside is sufficient, the external circulating medium storage container 22 stops supplementing liquid. The temperature control and the reactor body 18 realize product heat exchange. After the reaction is completed, the product in the reactor is discharged, and the inside is cleaned, sterilized and waited for the next use.
[0043] The above embodiments are only used to illustrate the technical solutions of the present application, and are not limited thereto; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that the technical solutions recorded in the foregoing embodiments can still be modified, or some or all of the technical features can be replaced equivalently; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application.
Claims
1. A temperature control device, characterized by, The application relates to a water tank with a heat exchange function, which comprises a shell (1), a water tank (2), a refrigeration assembly, a heating assembly and a heat medium circulation assembly. The water tank (2) is arranged inside the shell (1), the refrigeration assembly is connected to the inner side of the water tank (2) and is used for cooling the heat medium in the water tank (2), the heating assembly is connected to the inner side of the water tank (2) and is used for heating the heat medium in the water tank (2), and the heat medium circulation assembly is connected to the inner side of the water tank (2) and is used for conveying and recycling the heat medium in the water tank (2).
2. The temperature control device of claim 1, wherein The refrigeration assembly comprises an evaporator (3), a compressor (4), a condenser (5) and an expansion valve (6), the evaporator (3) is arranged in the water tank (2), the evaporator (3) is connected to the compressor (4), the compressor (4) is connected to the condenser (5), the condenser (5) is connected to the expansion valve (6), and the expansion valve (6) is connected to the evaporator (3). An oil separator (7) is arranged on the connecting pipeline between the compressor (4) and the condenser (5), and a liquid injection valve (8) is further arranged on the condenser (5), and the other end of the liquid injection valve (8) is communicated with the connecting pipeline between the evaporator (3) and the compressor (4).
3. The temperature control device of claim 1, wherein, The heating assembly comprises an electric heater (9) arranged in the water tank (2).
4. The temperature control device of claim 1, wherein, The heat medium circulation assembly comprises a circulating pump (10) arranged in the water tank (2), the outlet end of the circulating pump (10) is connected to an outlet pipeline (11), the inlet end is connected to an inlet pipeline (12), and a pressure relief valve (13) is arranged on the outlet pipeline (11) and the inlet pipeline (12).
5. The temperature control device of claim 2, wherein, The water tank (2) is connected to a drain pipeline (14).
6. The temperature control device of claim 4, wherein, A pressure gauge (15) and a temperature probe (16) are arranged on the outlet pipeline (11).
7. The temperature control device of claim 4, wherein, A porous silencer (17) is arranged on the inlet pipeline (12).
8. The temperature control device of claim 2, wherein, A liquid level meter (24) is further arranged on the water tank (2).
9. A reactor based on the temperature control device according to any one of claims 1 to 8, characterized in that The application further relates to a reactor body (18) and a circulating medium storage container (22), a jacket (19) is arranged on the outer side of the reactor body (18), the inlet of the jacket (19) is connected to the outlet pipeline (11) through a first liquid conveying pipeline (20), the outlet of the jacket (19) is connected to the inlet pipeline (12) through a second liquid conveying pipeline (21), and the circulating medium storage container (22) is communicated with the liquid supplementing opening of the water tank (2) through a third liquid conveying pipeline (23).