Sampling device for biopharmaceutical detection

Abstract

The utility model relates to the technical field of biopharmacy detection, and discloses a sampling device for biopharmacy detection, which comprises a material pumping mechanism and a storage mechanism, and adopts a split structure arrangement, a sampling bottle is arranged as an independent structural component, and the two ends of the sampling bottle are communicated and controlled by using a sealing plug column; material taking and discharging communication can be achieved by switching the connecting direction of the end, the sampling bottle is connected and installed with the sampling suction pipe through a threaded structure during installation, pumping and sucking of liquid medicine can be achieved through the drawing suction force of the sampling plug column, and after sampling operation is completed, sampling operation of the next time can be conducted only by disassembling and replacing the sampling bottle. According to the quantitative material taking device, the steps of liquid medicine transferring and filling and suction pipe cleaning are omitted, the use convenience of the device is greatly improved, the displacement stroke of the sampling plug column can be controlled and adjusted by abutting against the limiting rod, quantitative material taking is achieved, meanwhile, the device can be matched with sampling bottles with different volumes for use, and the use flexibility of the device is greatly improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of biological pharmacy detection, specifically to a sampling device for biological pharmacy detection. BACKGROUND

[0002] In the biological pharmacy process, sampling detection is an indispensable procedure, and a special sampling device is needed to extract the liquid medicine sample for detection analysis.

[0003] The existing sampling device adopts a barrel tube type extraction structure, which uses a piston structure to extract the liquid medicine and store it in the inside of the tube, and the sample is placed in a special sampling container for storage through transfer. The operation is complicated, and when sampling different types of liquid medicine, the sampling barrel tube needs to be cleaned or replaced to avoid mixing of the liquid medicine affecting the detection. Therefore, a sampling device for biological pharmacy detection is proposed. UTILITY MODEL CONTENT

[0004] The utility model aims at providing a sampling device for biological pharmacy detection to solve the problems in the background art.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical scheme: a sampling device for biological pharmacy detection, comprising a material extraction mechanism and a storage mechanism, the material extraction mechanism comprising a sampling extraction pipe, a driving pull rod, a sampling plug column and an adjusting limiting rod, the sampling plug column being movably installed in the inside of the sampling extraction pipe under the driving of the driving pull rod, the driving pull rod penetrating and being bolted to the rear side of the sampling extraction pipe;

[0006] The storage mechanism comprises a sampling bottle, a sealing plug column, a mounting block and a spring, the sampling bottle being detachably installed at the end of the sampling extraction pipe, the sealing plug column being installed at the end of the sampling bottle under the cooperation of the mounting block and the spring.

[0007] As a preferred, the inside of the sampling extraction pipe is provided with a plug column sliding cavity, the sampling plug column is slidingly embedded and installed in the inside of the plug column sliding cavity, the driving pull rod is fixedly installed at the rear of the sampling plug column, the rear of the adjusting limiting rod movably penetrates the rear of the sampling extraction pipe, and the rear end of the driving pull rod is fixed with a buckle block.

[0008] As a preferred, the rear of the sampling extraction pipe is provided with an adjusting screw hole penetratingly, the end of the adjusting limiting rod penetrates and is screw-connected to the inside of the adjusting screw hole, and the upper part of the driving pull rod is uniformly provided with a scale line.

[0009] As preferred, the front end of the sampling tube is provided with a connecting screw mouth, both ends of the sampling bottle are provided with connecting screw heads, the connecting screw mouth is matched with the connecting screw head, the end of the sampling bottle is threadedly installed to the inner side of the connecting screw mouth through the connecting screw head, and the rear part of the connecting screw mouth is provided with a limiting ring seat.

[0010] As preferred, both ends of the sampling bottle are provided with communicating studs, the inner part of the communicating stud is provided with a mounting screw hole, the mounting plug is threadedly installed to the inner side of the mounting screw hole, the mounting plug is located at the opening side of the mounting screw hole, the end side of the sampling bottle and the middle part of the mounting plug are both provided with a material taking through hole, two sealing plug studs are provided, one of the sealing plug studs is abutted to the opening side of the material taking through hole of the mounting plug under the pushing of the spring, the other sealing plug stud is abutted to the opening side of the material taking through hole of the end of the sampling bottle under the pushing of the spring, and the outer circumferential side of the sampling bottle is provided with a pointing arrow and a sampling observation window.

[0011] As preferred, the end of the sampling bottle is provided with a material taking head seat, and the material taking head seat is threadedly installed to the front end of the sampling bottle.

[0012] As preferred, the end of the sampling bottle is provided with an end head cover, the number of the end head cover is two, and the two end head covers are threadedly installed to the front and rear ends of the sampling bottle respectively.

[0013] Compared with the prior art, the above technical scheme has the following technical effects:

[0014] The sampling device adopts a split structure, the sampling bottle is arranged as an independent structural component, the two ends of the sampling bottle are communicated and controlled by the sealing plug stud, the material taking and discharging communication can be realized by switching the end head connection direction, the sampling bottle is connected and installed with the sampling tube through the threaded structure during installation, the liquid medicine can be pumped and sucked through the pulling and sucking force of the sampling plug stud, the sampling bottle is communicated with the sampling tube through the pressure difference, the liquid medicine will not enter the inside of the sampling tube during the process, only the sampling bottle needs to be disassembled and replaced after the sampling operation is completed, the next sampling operation can be performed, the steps of liquid medicine moving and the tube cleaning are saved, the use convenience of the device is greatly improved, the displacement stroke of the sampling plug stud can be controlled and adjusted by abutting and limiting the limiting rod arranged at the rear part of the sampling tube, the device can be used with sampling bottles of different volumes while realizing the quantitative material taking, and the use flexibility of the device is greatly improved. BRIEF DESCRIPTION OF DRAWINGS

[0015] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the accompanying drawings needed to be used in the description of the embodiments or the prior art will be briefly introduced. Obviously, the accompanying drawings described below only represent some of the embodiments of the present application, and not all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative labor fall within the scope of the present application.

[0016] Figure 1 It is a schematic diagram of the overall installation structure of the present application.

[0017] Figure 2 It is a schematic diagram of the overall split structure of the present application.

[0018] Figure 3 It is a schematic diagram of the cross-sectional structure of the material drawing mechanism of the present application.

[0019] Figure 4 It is a schematic diagram of the cross-sectional structure of the storage mechanism of the present application.

[0020] Figure 5 It is a schematic diagram of the cross-sectional structure of the storage mechanism of the present application. Figure 4 It is a schematic diagram of the structure of area A.

[0021] Figure 6 It is a schematic diagram of the installation structure of the sampling bottle and the end cap of the present application.

[0022] Reference signs: 1, sampling drawing pipe; 2, driving pull rod; 3, sampling plug column; 4, adjusting limiting rod; 5, sampling bottle; 6, sealing plug column; 7, installation sealing block; 8, spring; 9, buckling block; 10, scale mark line; 11, connecting screw port; 12, limiting ring seat; 13, connecting screw head; 14, communication column head; 15, material drawing through hole; 16, material drawing head seat; 17, end cap; 18, pointing arrow; 19, sampling observation window. DETAILED DESCRIPTION

[0023] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments only represent some of the embodiments of the present application, and not all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative labor fall within the scope of the present application.

[0024] It is to be understood that the structure, proportion, size and the like shown in the drawings of the present specification are only used to cooperate with the disclosed content, to be understood and read by those skilled in the art, and are not used to limit the implementation conditions of the present application, so they do not have technical significance. Any modification of structure, change of proportion relationship or adjustment of size, without affecting the effect and purpose of the present application, should still fall within the scope of the disclosed technology.

[0025] Embodiment one

[0026] Please refer to Figures 1-5 The utility model provides a technical scheme: a sampling device for biopharmaceutical detection, including material pumping mechanism and storage mechanism, material pumping mechanism is used for the extraction drive of liquid medicine, and material pumping mechanism includes sampling pump 1, drive pull rod 2, sampling plug column 3 and adjusting limit rod 4, in order to facilitate the connection installation of sampling plug column 3, as shown in the inside of sampling pump 1 is provided with plug column sliding cavity, sampling plug column 3 is slidably embedded in the inside of plug column sliding cavity, drive pull rod 2 is fixedly installed at the rear of sampling plug column 3, the rear of adjusting limit rod 4 is movably penetrated through the rear of sampling pump 1, sampling plug column 3 is movably installed in the inside of sampling pump 1 under the drive of drive pull rod 2, and vacuum suction force can be generated by changing the internal cavity volume of plug column sliding cavity, in order to facilitate the sliding drive of sampling plug column 3, the rear end of drive pull rod 2 is fixed with buckle pull block 9. Figure 3 In order to facilitate the stroke adjustment of sampling plug column 3, as shown in the rear side of sampling pump 1 is installed with drive pull rod 2, in order to facilitate the connection installation of sampling plug column 3, adjusting screw hole is provided in the rear of sampling pump 1, the end of adjusting limit rod 4 is penetrated and screw-connected to the inside of adjusting screw hole, the displacement stroke of sampling plug column 3 can be controlled and adjusted by abutting and limiting adjusting limit rod 4, while realizing quantitative material taking, the device can be used with different volume sampling bottles 5, greatly improving the use flexibility of the device, in order to facilitate the adjustment reference of adjusting limit rod 4, the upper part of drive pull rod 2 is uniformly provided with scale mark 10.

[0027] Figure 3 In order to facilitate the stroke adjustment of sampling plug column 3, as shown in the rear side of sampling pump 1 is installed with drive pull rod 2, in order to facilitate the connection installation of sampling plug column 3, adjusting screw hole is provided in the rear of sampling pump 1, the end of adjusting limit rod 4 is penetrated and screw-connected to the inside of adjusting screw hole, the displacement stroke of sampling plug column 3 can be controlled and adjusted by abutting and limiting adjusting limit rod 4, while realizing quantitative material taking, the device can be used with different volume sampling bottles 5, greatly improving the use flexibility of the device, in order to facilitate the adjustment reference of adjusting limit rod 4, the upper part of drive pull rod 2 is uniformly provided with scale mark 10.

[0028] Storage mechanism is used for the collection and storage of liquid medicine samples, and the storage mechanism includes sampling bottle 5, sealing plug 6, mounting block 7 and spring 8, as shown in Figure 3 ​As shown, in order to facilitate the installation of the sampling bottle 5, a connecting screw port 11 is arranged at the front end of the sampling pipe 1, both ends of the sampling bottle 5 are provided with a connecting screw head 13, the connecting screw port 11 is matched with the connecting screw head 13, the end of the sampling bottle 5 is screwed to the inside of the connecting screw port 11 through the connecting screw head 13, the sampling bottle 5 is arranged as an independent structural component, and is connected and installed with the sampling pipe 1 through the threaded structure during installation. The liquid medicine can be pumped and sucked through the pulling force of the sampling plug column 3. The sampling bottle 5 and the sampling pipe 1 are communicated through the pressure difference, and the liquid medicine will not enter the inside of the sampling pipe 1 during the process. After the sampling operation is completed, the next sampling operation can be performed by only disassembling and replacing the sampling bottle 5, thereby saving the steps of liquid medicine transfer and pipe cleaning. In order to limit the sliding of the sampling plug column 3 and provide resistance support for the installation of the sampling bottle 5, a limiting ring seat 12 is arranged at the rear of the connecting screw port 11.

[0029] In order to facilitate component installation, as shown in the attached Figure 4 As shown, a communication column head 14 is arranged at both ends of the sampling bottle 5, an installation screw hole is arranged in the inside of the communication column head 14, the sealing plug column 6, the installation sealing block 7 and the spring 8 are all installed in the inside of the installation screw hole, a screw thread is arranged at the front of the installation screw hole, the installation sealing block 7 is screwed to the inside of the installation screw hole, and the installation sealing block 7 is located at the opening side of the installation screw hole. As a sealing and closing structure of the sealing plug column 6 and the spring 8, in order to facilitate the flow of liquid medicine, a material taking through hole 15 is provided at the end side of the sampling bottle 5 and the middle part of the installation sealing block 7, as shown in the attached Figure 4 As shown, two sealing plug columns 6 are arranged, one sealing plug column 6 is in contact with the opening side of the material taking through hole 15 of the installation sealing block 7 under the pushing of the spring 8, and the other sealing plug column 6 is in contact with the opening side of the material taking through hole 15 of the end of the sampling bottle 5 under the pushing of the spring 8, thereby forming a one-way communication control structure. The material taking and discharging communication can be realized by switching the end head connection direction. In order to facilitate the confirmation of the installation direction, a pointing arrow 18 is arranged at the outer circumferential side of the sampling bottle 5. In order to facilitate the observation of the liquid medicine sample, a sampling observation window 19 is arranged at the outer circumferential side of the sampling bottle 5.

[0030] In order to facilitate the sucking of the liquid medicine sample, as shown in the attached Figure 1 As shown, a material taking head seat 16 is arranged at the end of the sampling bottle 5, the material taking head seat 16 is screwed to the front end of the sampling bottle 5, and a material taking suction pipe is arranged at the front of the material taking head seat 16, thereby facilitating the sucking operation of the liquid medicine.

[0031] Working principle or structural principle, when in use, select a sampling bottle 5 of appropriate capacity according to the sampling needs, then adjust the telescopic degree of the limit rod 4 by screwing, and match it with the scale mark 10 on the upper part of the driving rod 2 to complete the stroke adjustment of the sampling plug 3, ensure that the extraction volume of the sampling tube 1 is less than the rated volume of the sampling bottle 5, keep the sampling plug 3 in the initial position, and then make the material collection end of the sampling bottle 5 consistent with the pointing side of the pointing arrow 18, and install the sampling bottle 5 on the front of the sampling tube 1 by screwing. After completion, install the material collection head seat 16 on the front end of the sampling bottle 5 by screwing, and then move the device to the sampling position of the silo, insert the end of the material collection head seat 16 into the interior of the silo, and then pull the driving rod 2 backward through the buckle pull block 9, and use the vacuum suction generated by the pressure difference to move the sealing plug 6 at the rear end of the sampling bottle 5 backward. When the bottle 5 is in the open position, the sealing plug 6 at the front end of the bottle 5 moves backward to separate from the material taking hole 15 on the side of the mounting block 7, thereby realizing the communication between the bottle 5 and the hopper, and the medicine enters the bottle 5 through the material taking hole 15. When the sampling plug 3 contacts the end of the regulating limit rod 4, the material taking stops, and the sealing plugs 6 on both sides of the sampling bottle 5 are re-fitted and sealed by the thrust of the spring 8 after losing the suction effect, thereby realizing the sealing of the material taking hole 15 at the end of the sampling bottle 5. Thereafter, the sampling bottle 5 is disassembled and replaced to complete the sampling operation. When discharging the medicine liquid, it is only necessary to switch the mounting end of the sampling bottle 5. Similarly, the external air pressure thrust can complete the opening drive of the material taking hole 15 on both sides of the sampling bottle 5, thereby realizing the discharge operation of the medicine liquid sample in the sampling bottle 5.

[0032] Example 2

[0033] See also Figure 6 , which is different from the first embodiment: Figure 6 As shown, the end of the sampling bottle 5 is provided with an end cap 17 , and there are two end caps 17 . The two end caps 17 are respectively threadedly installed on the front and rear ends of the sampling bottle 5 .

[0034] Working principle or structural principle, the end cap 17 is used to seal the end of the sampling bottle 5 and is used for mobile transportation protection of the sampling bottle 5. During installation, the end cap 17 is screwed and installed on the two side end portions of the sampling bottle 5 in turn, which can prevent the end of the sampling bottle 5 from being damaged by collision during transportation.

[0035] In summary, the sampling device adopts a split structure, the sampling bottle 5 is arranged as an independent structural component, the two ends of the sampling bottle 5 are communicated and controlled by the sealing plug column 6, the sampling and discharging communication can be realized by switching the end connection direction, when installed, the sampling bottle 5 is connected and installed with the sampling pipe 1 through the threaded structure, the liquid medicine can be pumped and sucked through the pulling suction force of the sampling plug column 3, the sampling bottle 5 is communicated with the sampling pipe 1 through the pressure difference, the liquid medicine will not enter the inside of the sampling pipe 1 in the process, after the sampling operation is completed, the next sampling operation can be carried out only by disassembling and replacing the sampling bottle 5, the steps of liquid medicine moving and cleaning the pipe are saved, the use convenience of the device is greatly improved, and the adjusting limiting rod 4 is arranged at the rear part of the sampling pipe 1, the displacement stroke of the sampling plug column 3 can be controlled and adjusted by abutting and limiting the adjusting limiting rod 4, the device can be used with the sampling bottle 5 of different volumes while realizing quantitative sampling, the use flexibility of the device is greatly improved.

[0036] Those skilled in the art can understand that the features described in various embodiments and / or claims of the present application can be combined or / and combined, even if such combinations or combinations are not explicitly described in the present application. In particular, the features described in various embodiments and / or claims of the present application can be combined and / or combined without departing from the spirit and teachings of the present application. All these combinations and / or combinations fall within the scope of the present application.

Claims

1. A sampling device for biopharmaceutical testing comprising a draw mechanism and a storage mechanism, characterized by: The sampling mechanism comprises a sampling pipe (1), a driving pull rod (2), a sampling plug column (3) and an adjusting limiting rod (4), the sampling plug column (3) is movably installed in the sampling pipe (1) under the driving of the driving pull rod (2), and the driving pull rod (2) penetrates and is bolted to the rear side of the sampling pipe (1); The storage mechanism comprises a sampling bottle (5), a sealing plug column (6), an installation block (7) and a spring (8), the sampling bottle (5) is detachably installed at the end of the sampling pipe (1), and the sealing plug column (6) is blocked and installed at the end of the sampling bottle (5) under the cooperation of the installation block (7) and the spring (8).

2. The sampling device for biopharmaceutical detection according to claim 1, characterized in that: The inside of the sampling pipe (1) is provided with a plug column sliding cavity, the sampling plug column (3) is slidingly and fitly installed in the inside of the plug column sliding cavity, the driving pull rod (2) is fixedly installed at the rear of the sampling plug column (3), the rear of the adjusting limiting rod (4) movably penetrates the rear of the sampling pipe (1), and the rear end of the driving pull rod (2) is fixedly provided with a buckling block (9).

3. The sampling device for biopharmaceutical detection according to claim 2, characterized in that: The rear of the sampling pipe (1) is provided with an adjusting screw hole, the end of the adjusting limiting rod (4) penetrates and is screw-connected to the inside of the adjusting screw hole, and the upper part of the driving pull rod (2) is uniformly provided with a scale line (10).

4. The sampling device for biopharmaceutical detection according to claim 3, wherein: The front end of the sampling pipe (1) is provided with a connecting screw mouth (11), both ends of the sampling bottle (5) are provided with connecting screw heads (13), the connecting screw mouth (11) is matched with the connecting screw head (13), the end of the sampling bottle (5) is screw-installed to the inside of the connecting screw mouth (11) through the connecting screw head (13), and the rear of the connecting screw mouth (11) is provided with a limiting ring seat (12).

5. The sampling device for biopharmaceutical detection according to claim 4, characterized in that: Both ends of the sampling bottle (5) are provided with communicating column heads (14), the inside of the communicating column head (14) is provided with an installation screw hole, the installation block (7) is screw-installed to the inside of the installation screw hole, the installation block (7) is located at the opening side of the installation screw hole, the end side of the sampling bottle (5) and the middle part of the installation block (7) are both provided with a sampling material through hole (15), the sealing plug column (6) is provided with two, one of the sealing plug columns (6) is abutted to the opening side of the sampling material through hole (15) of the installation block (7) under the pushing of the spring (8), the other of the sealing plug columns (6) is abutted to the opening side of the sampling material through hole (15) of the end of the sampling bottle (5) under the pushing of the spring (8), and the outer circumferential side of the sampling bottle (5) is provided with a pointing arrow (18) and a sampling observation window (19).

6. The sampling device for biopharmaceutical detection according to claim 5, characterized in that: The end of the sampling bottle (5) is provided with a sampling head seat (16), and the sampling head seat (16) is screw-installed to the front end of the sampling bottle (5).

7. The sampling device for biopharmaceutical detection according to claim 5, wherein: The end of the sampling bottle (5) is provided with end head covers (17), the number of the end head covers (17) is two, and the two end head covers (17) are screw-installed to the front and rear ends of the sampling bottle (5) respectively.

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