Embryo transplantation tube

Abstract

The embryo transplantation tube comprises an outer sleeve and an inner core tube arranged in the outer sleeve, the front end of the outer sleeve is connected with a bending part which can be conveniently inserted into a female genital tract, and a first volume prompting line and a second volume prompting line are arranged at the position, close to the front end, of the inner core tube from front to back at intervals; the embryo transfer tube disclosed by the utility model is convenient for clinical medical personnel to observe the position of the embryo transfer tube in the uterus in the process of transporting the embryo into the uterus, and meanwhile, the amount of liquid sucked when the embryo is transferred can be specified and standardized, so that the embryo is convenient to load, and the clinical medical personnel can transfer the embryo under ultrasound more conveniently.

Description

Technical Field

[0001] This utility model relates to the field of embryo transfer technology, and in particular to an embryo transfer tube. Background Technology

[0002] Embryo transfer, also known as embryo transfer, refers to the technique of transferring an early embryo from a female animal, or an embryo obtained through in vitro fertilization or other methods, into the female animal's body so that it can continue to develop into a new individual. In human assisted reproductive technology, embryologists generally load early embryos or blastocysts into embryo transfer catheters and then hand them over to clinicians. Under ultrasound guidance, the clinicians insert the embryo transfer catheter into the infertile patient's uterus, push the transfer fluid containing the embryo and an air column together into the appropriate position in the patient's uterus, and then withdraw the embryo transfer catheter.

[0003] Currently, the commonly used embryo transfer catheter consists of two parts: a guide tube (outer tube) and a transfer tube (inner core). The transfer tube (inner core) is usually transparent and unmarked or has an ultrasound guide line. Reproductive centers typically use a three-stage liquid loading method for embryo loading. First, a special syringe is connected to the transfer catheter. After checking for airtightness, a section of embryo transfer fluid is drawn, followed by a section of air. Then, the embryo to be transferred is drawn into the inner core of the transfer tube. The embryo-loaded transfer tube is carefully taken to the transfer room for transfer. The transfer tube containing the embryo is carefully handed to the transfer physician, who slowly inserts the embryo into the uterine cavity. When the tip of the embryo transfer tube is at least 0.5 mm from the fundus of the uterus, the syringe is gently pushed to inject the embryo-containing culture medium into the uterine cavity. However, in actual operation, clinical medical staff often find the ultrasound guide line blurry during ultrasound examination, rendering it ineffective. Clinical staff can only determine the position of the transfer tube in the uterus and whether the embryo has been transferred to the optimal implantation location based on the positional changes of the air column within the transfer tube (inner core).

[0004] Therefore, there is an urgent need to develop an embryo transfer tube that allows clinicians to easily observe the position of the embryo transfer tube within the uterus during embryo transport, while also specifying and standardizing the amount of fluid aspirated during embryo transfer, facilitating embryo loading and making ultrasound-guided embryo transfer more convenient for clinicians. Utility Model Content

[0005] In view of this, the purpose of this utility model is to provide an embryo transfer tube.

[0006] The embryo transfer tube of this utility model includes an outer tube and an inner core tube disposed inside the outer tube. The front end of the outer tube is connected to a curved part that facilitates insertion into the female reproductive tract. The inner core tube is provided with a first volume indicator line and a second volume indicator line at intervals from front to back near the front end.

[0007] Furthermore, the front section of the inner core tube is a transparent flexible tube adapted to the bend of the outer tube, and the body of the inner core tube is a hollow rigid tube.

[0008] Furthermore, a limiting ring is provided between the curved portion of the outer sheath and the outer sheath body to prevent displacement of the outer sheath at the cervix.

[0009] Furthermore, the limiting ring is made of transparent plastic or transparent silicone, and the outer diameter of the limiting ring is larger than the outer diameter of the outer sleeve.

[0010] Furthermore, the volume inside the inner core tube between the first volume indication line and the inner core tube opening is 2 microliters, and the volume inside the inner core tube between the second volume indication line and the inner core tube opening is 4 microliters.

[0011] Furthermore, the transparent flexible tube and the rigid tube are connected by a plug-in connection.

[0012] Furthermore, the outer tube has a guide head at the front end of the curved portion, the guide head being small at both ends and large in the middle, and having an opening for the inner core tube to extend out.

[0013] Furthermore, the handheld end of the outer tube is provided with an outer tube seat, and the handheld end of the inner core tube is provided with an inner core tube seat.

[0014] Furthermore, the interior of the outer tube seat is conformally matched to the exterior of the inner core tube seat.

[0015] Furthermore, the transparent flexible tube of the inner core tube is inserted into the outer tube from the outer tube seat. After being inserted into the outer tube, the transparent flexible tube extends out from the opening of the guide head and enters the uterus under the guidance of the bend.

[0016] The beneficial effects of this invention are as follows: The embryo transfer tube of this invention allows clinical medical personnel to easily observe the position of the embryo transfer tube in the uterus during the process of transporting the embryo into the uterus. At the same time, it can also specify and standardize the amount of fluid absorbed during embryo transfer, which is convenient for embryo loading and makes it easier for clinical medical personnel to perform ultrasound-guided embryo transfer. Attached Figure Description

[0017] The present invention will be further described below with reference to the accompanying drawings and embodiments:

[0018] Figure 1 It is a structural diagram of the utility model; Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0020] In the description of this utility model, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0021] Figure 1 As shown in the figure, the embryo transfer tube of this embodiment includes an outer tube 1 and an inner core tube 2 disposed inside the outer tube 1. The front end of the outer tube 1 is connected to a curved portion 102 for easy insertion into the female reproductive tract. The inner core tube 2 has a first volume indicator line 202 and a second volume indicator line 203 spaced from front to back near the front end. The outer tube 1 is usually made of a relatively rigid material to provide structural support and help the inner core tube 2 pass smoothly through the cervix. The curved portion 102 is usually made of a soft material, such as medical silicone or polyethylene, to ensure minimal damage to the uterus and embryo during the embryo transfer procedure. The front end of 1 is connected to the curved part 102. The curved part 102 is more adaptable to the physiological structure of the female reproductive tract, so that it can more easily pass through the cervix into the uterine cavity for embryo transfer. The inner core tube 2 is a tubular structure used to directly transport the embryo into the uterus. The inner core tube 2 contains the embryo to be transferred, the transfer fluid, and the air column. The embryo transfer fluid has high biocompatibility and bioactivity, which can provide a suitable environment, increase the success rate of conception, and promote the implantation and development of the embryo. Under B-ultrasound observation, the position of the transfer tube in the uterus is determined by the relative positional change of the air column in the inner core tube 2 with the first volume indicator line 202 and the second volume indicator line 203.

[0022] In this embodiment, the front section of the inner core tube 2 is a transparent flexible tube 201 adapted to the bending part 102, and the body of the inner core tube 2 is a hollow rigid tube; the front section of the inner core tube 2 is made of a transparent flexible tube 201. The transparency of the tube ensures that the loaded embryo, transfer fluid and air column can be visualized during the embryo loading process, and the loading volume is more controllable. The characteristics of the flexible tube ensure that the inner core tube 2 can be effectively guided into the uterus through the bending part 102 after being inserted into the outer tube 1.

[0023] In this embodiment, a limiting ring 101 is provided between the curved portion 102 of the outer tube and the body of the outer tube 1 to prevent the outer tube 1 from shifting at the cervix. The limiting ring 101 is used to fix the embryo transfer tube at the cervix of the human body. On the one hand, it provides a support point for the embryo transfer tube, which is stable and conducive to implanting the embryo. On the other hand, it can effectively prevent the embryo transfer tube from shifting due to improper operation.

[0024] In this embodiment, the limiting ring 101 is made of transparent plastic or transparent silicone, and the outer diameter of the limiting ring 101 is larger than the outer diameter of the outer tube 1. The limiting ring 101 is made of transparent plastic or transparent silicone, which can reduce the pressure on the cervix during the embryo transfer procedure, reduce the feeling of foreign body and pain. The outer diameter of the limiting ring 101 is larger than the outer diameter of the outer tube 1, which can effectively support the limiting ring 101 and prevent the embryo transfer tube from shifting at the cervix.

[0025] In this embodiment, the volume of the inner core tube 2 between the first volume indicator line 202 and the inner core tube opening 205 is 2 μL, and the volume of the inner core tube 2 between the second volume indicator line 203 and the inner core tube opening 205 is 4 μL. When performing the three-stage embryo loading method, the embryologist observes the volume indicator lines under a microscope and loads both segments of embryo transfer fluid into 2 μL each. The loading sequence is as follows: first, 2 μL of embryo transfer fluid is drawn in through the inner core tube opening 205, then the first air column is drawn in. The volume of the first air column in the inner core tube 2 is 2 μL. After the first air column is drawn in, the embryo to be transferred is loaded. The embryo uses the embryo transfer fluid as a carrier, and the total volume of the embryo and embryo transfer fluid in the inner core tube 2 is 4 μL. After the embryo transfer fluid for loading the embryo is loaded in the inner core tube, the second air column is drawn in. The volume of the second air column in the inner core tube 2 is 2 μL. Finally, the embryo transfer fluid for loading the embryo is drawn in again. Two microliters of embryo transfer fluid are introduced. Because the inner tube 2 has a first volume indicator line 202 and a second volume indicator line 203 spaced apart from front to back near the front end, and the volume of the inner tube 2 between the first volume indicator line 202 and the inner tube opening 205 is 2 microliters, while the volume between the second volume indicator line 203 and the inner tube opening 205 is 4 microliters, the second air column is positioned precisely between the first volume indicator line 202 and the second volume indicator line 203. The final 2 microliters of embryo transfer fluid are positioned precisely between the first volume indicator line 202 and the inner tube opening 205. This process specifies and standardizes the amount of fluid to be loaded for each embryo transfer. During the transfer process, the relative displacement between the two air columns and the first and second volume indicator lines 202 and 203 can be observed under ultrasound to determine the embryo's position and whether it has been transferred to the uterus.

[0026] In this embodiment, the transparent flexible tube 201 and the rigid tube are connected by a plug-in connection. Since the transparent flexible tube 201 and the rigid tube are made of different materials, the plug-in connection is simple and quick, requires no special tools, and is easy to install and disassemble. The plug-in connection can also provide good sealing to prevent liquid leakage.

[0027] In this embodiment, the front end of the curved portion 102 of the outer sheath 1 is provided with a guide head 103. The guide head 103 is small at both ends and large in the middle, and has an opening for extending the inner core tube 2. The design of the guide head 103, which is small at both ends and large in the middle, makes the outer sheath 1 pass through the cervix and enter the uterus more smoothly, reducing friction and damage to the endometrium, thereby reducing the risk of postoperative complications and reducing patient discomfort.

[0028] In this embodiment, the handheld end of the outer tube 1 is provided with an outer tube seat 104, and the handheld end of the inner core tube 2 is provided with an inner core tube seat 204. The interior of the outer tube seat 104 conforms to the exterior of the inner core tube seat 204. The transparent tube 201 of the inner core tube 2 is inserted into the outer tube 1 through the outer tube seat 104. After being inserted into the outer tube 1, the transparent tube 201 extends from the head opening into the uterus under the guidance of the bend 102. The outer tube seat 104 and the inner core tube seat 204 can provide a better grip during embryo transfer, allowing doctors to hold the transfer tube more stably and reduce hand tremors during embryo transfer. This design improves the precision of the procedure. The outer tube seat 104 can also be equipped with corresponding scales or markings, allowing doctors to more accurately control the insertion depth of the transfer tube and ensure the embryo is placed in the optimal position within the uterus. The design of the outer tube seat 104 also prevents doctors from accidentally pushing the transfer tube during the procedure, thus avoiding the embryo being placed in the wrong position. The interior of the outer tube seat 104 conforms to the exterior of the inner core tube seat 204. After the inner core tube 2 is fully inserted into the outer tube 1, the interior of the outer tube seat 104 conforms to the exterior of the inner core tube seat 204, preventing the inner core tube 2 from shaking within the outer tube 1 and affecting embryo transfer.

[0029] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model and are not intended to limit it. Although this utility model has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of this utility model without departing from the spirit and scope of the technical solutions of this utility model, and all such modifications or substitutions should be covered within the scope of the claims of this utility model.

Claims

1. An embryo transfer tube, characterized in that: include: The outer tube and the inner core tube disposed inside the outer tube, the front end of the outer tube is connected to a curved part that facilitates insertion into the female reproductive tract, and the inner core tube is provided with a first volume indicator line and a second volume indicator line at intervals from front to back near the front end.

2. The embryo transfer tube according to claim 1, characterized in that: The front section of the inner core tube is a transparent flexible tube adapted to the bend of the outer tube, and the body of the inner core tube is a hollow rigid tube.

3. The embryo transfer tube according to claim 1, characterized in that: A limiting ring is provided between the curved part of the outer tube and the body of the outer tube to prevent displacement of the outer tube at the cervix.

4. The embryo transfer tube according to claim 3, characterized in that: The limiting ring is made of transparent plastic or transparent silicone, and the outer diameter of the limiting ring is larger than the outer diameter of the outer sleeve.

5. The embryo transfer tube according to claim 1, characterized in that: The volume inside the inner core tube between the first volume indicator line and the inner core tube opening is 2 microliters, and the volume inside the inner core tube between the second volume indicator line and the inner core tube opening is 4 microliters.

6. The embryo transfer tube according to claim 2, characterized in that: The transparent flexible tube and the rigid tube are connected by a plug-in connection.

7. The embryo transfer tube according to claim 1, characterized in that: The outer tube has a guide head at the front end of the curved section. The guide head is small at both ends and large in the middle, and has an opening for the inner core tube to extend out.

8. The embryo transfer tube according to claim 7, characterized in that: The outer tube has a handheld end with an outer tube seat, and the inner tube has a handheld end with an inner tube seat.

9. The embryo transfer tube according to claim 8, characterized in that: The interior of the outer tube seat conforms to the exterior of the inner core tube seat.

10. The embryo transfer tube according to claim 8, characterized in that: The transparent flexible tube of the inner core tube is inserted into the outer tube from the outer tube seat. After being inserted into the outer tube, the transparent flexible tube extends out from the opening of the guide head and enters the uterus under the guidance of the bend.

Images