Granular medicine granulator
The inclined structure of the granular drug granulator uses a combination of filtering and extrusion components to solve the problem of powder increase during drug extrusion, and achieves stable separation of drug powder and efficient granulation.
Patent Information
- Application Number
- CN202422473040.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-14
- Publication Date
- 2025-10-28
- Estimated Expiration
- 2034-10-14
AI Technical Summary
In the process of drug extrusion granulation, the existing technology easily produces smaller dust, which makes the particles unstable and requires secondary separation. The secondary separation may cause the particles to collide and be squeezed again to form powder, increasing the amount of powder.
A granular drug granulator with an inclined structure is designed. The powder is directly separated into granules through filtering of the feed component, extrusion of the rotating component, and separation of the filtering component. The chamfered structure and the volute extrusion block of the rotating component are combined with the filter frame and the separation plate to ensure that the powder is stably extruded into granules and the powder is separated.
The stable extrusion of drug powder into granules is achieved, the generation of powder is reduced, the stability and efficiency of the granulation process are improved, and the separation effect of drug granules and powder is significantly improved.
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Figure CN223474119U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of pharmaceutical equipment technology, and in particular to a granulation machine for granulated drugs. Background Technology
[0002] With the continuous development of science and technology, people's medical level is also improving. For various intractable diseases, they can be directly treated with drugs. Modern drug manufacturing technology has the ability to extract some effective ingredients better, making the drugs more effective. In terms of drug absorption, the shape of the drug capsule can ensure better absorption. The capsule usually contains drug particles to facilitate absorption.
[0003] In the current process of extruding and granulating drugs, some smaller dust particles are inevitably present. A secondary process is required to separate the powder from the granules. The resulting granules are not stable enough, and the secondary separation can cause the granules to be collided and squeezed again, resulting in an increase in the amount of powder formed. Utility Model Content
[0004] This disclosure relates to a granulation machine for pharmaceuticals. The machine frame is designed with an inclined structure to facilitate the discharge of granules. The feed inlet of the feeding component is filtered, and then the feeding component rotates with the rotating component. The extrusion component extrudes the powder, allowing the powder to be squeezed out of the rotating component. The separation component separates the powder from the rotating component to form granules. After passing through the filtration component, the smaller powder particles are separated, achieving the direct separation of granules and powder.
[0005] In a first aspect, this disclosure provides a granulation machine for granulated drugs, specifically comprising: a machine frame; a rotating assembly rotatably mounted inside the machine frame, a feeding assembly mounted at the upper end of the rotating assembly, an extrusion assembly disposed inside the rotating assembly at the bottom of the feeding assembly, the bottom of the extrusion assembly being fixed to the bottom of the machine frame, a filtering assembly disposed on the upper outer side of the rotating assembly, the filter frame of the filtering assembly being disposed at the chamfered position at the upper end of the rotating assembly, the filter frame being configured as a mesh frame, a brush plate mounted at the bottom of the separation plate of the separation assembly at the position of the filter frame, an auxiliary assembly mounted at the machine frame position at the bottom of the filtering assembly, a discharge plate mounted on the right side of the machine frame corresponding to the filtering assembly, a separation assembly mounted at the discharge plate of the machine frame, the end of the separation assembly contacting the upper outer wall of the rotating assembly.
[0006] In at least some embodiments, the feed hopper of the feeding assembly is configured as a funnel-shaped structure, and a top filter frame is snapped into place inside the feed hopper. The top filter frame is configured as a mesh frame structure.
[0007] In at least some embodiments, the rotating frame of the rotating assembly is rotatably mounted on the machine frame, and a drive motor is installed on one side of the bottom of the rotating frame, with the drive motor meshing with the bottom of the rotating frame.
[0008] In at least some embodiments, the top corners of the rotating frame are chamfered, a connecting cylinder is provided at the top of the rotating frame, the bottom of the connecting cylinder is cylindrical, and a discharge hole is provided on the bottom outer wall of the connecting cylinder.
[0009] In at least some embodiments, the fixed shaft of the extrusion assembly is fixed at the bottom of the machine frame, and an extrusion block is provided at the top of the fixed shaft. The extrusion block is placed inside the connecting cylinder of the rotating assembly, and the extrusion block is configured as a volute block structure.
[0010] In at least some embodiments, the outer frame of the separation component is fixed to the outer wall of the machine frame near the unloading plate, a separation plate is hinged on the outer frame, the end of the separation plate contacts the conical outer wall of the connecting cylinder of the rotating component, and a connecting rod is installed between the separation plate and the outer frame.
[0011] In at least some embodiments, the auxiliary frame of the auxiliary component is disposed at the bottom of the filter component inside the machine frame, the auxiliary frame is inclined, and a discharge plate is disposed at the outer end of the bottom position of the auxiliary frame.
[0012] This utility model provides a granulation machine for granulated drugs, which has the following beneficial effects:
[0013] In this invention, the entire frame is tilted to allow the granules to be discharged more easily from the feed plate. The powder is poured in from the feeding component, which filters the powder and then contacts the extrusion component inside the rotating component. The extrusion component extrudes the powder from the discharge hole. At this time, the separation component peels the extruded powder from the discharge hole, and the resulting granules fall onto the filtering component. The filtering component separates the granules from some powder, allowing the powder to be discharged from the auxiliary component, while the granules are discharged directly through the feed plate, thus achieving the separation and discharge of granules and powder.
[0014] In addition, the rotating component is set as the main moving part of the device, while the extrusion component is fixed. The rotating frame is set to be rotated, so that when the drive motor drives the rotating frame, the rotating component rotates as a whole. This facilitates the subsequent extrusion and granulation of the medicine powder within the rotating component. First, the top edge of the rotating frame is set as a chamfered structure, allowing the medicine granules to slide outward better through the chamfered structure. The bottom of the connecting cylinder is set as a cone shape, which provides greater stability when the medicine powder is granulated through the discharge hole.
[0015] In addition, after the powder enters the extrusion block position inside the connecting cylinder, the extrusion assembly is fixed to the machine frame by a fixed shaft, while the rotating assembly rotates. At this time, the powder is squeezed against the inner wall of the connecting cylinder by the volute structure of the extrusion block, so that the powder is discharged from the discharge hole, thus achieving the granulation effect of the powder.
[0016] In addition, the end of the separator plate is set to be tightly attached to the outer wall of the connecting cylinder, so that the rotating connecting cylinder contacts the end of the separator plate, so that the drug particles extending from the discharge hole are separated by the separator plate, thus completing the granulation of the drug powder. A connecting rod is added between the outer frame and the separator plate to allow the separator plate to fit more tightly to the outer wall of the connecting cylinder for use.
[0017] In addition, after the granules pass through the beveled corner of the rotating component and face the filter frame, the mesh structure of the filter frame will filter them, allowing the filter frame to separate the granules from some of the powder. The brush plate set at the separation component allows the granules in the filter frame to be better discharged from the feed plate. An auxiliary frame is set at the bottom of the filter component. The inclined auxiliary frame can guide the powder to be discharged. The discharge plate at the bottom of the auxiliary frame is convenient for external tools to collect. Attached Figure Description
[0018] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings of the embodiments will be briefly described below.
[0019] The accompanying drawings described below are only related to some embodiments of the present invention and are not intended to limit the scope of the present invention.
[0020] In the attached diagram:
[0021] Figure 1 A schematic diagram of the overall structure of this application is shown;
[0022] Figure 2 A schematic diagram of the auxiliary component structure of this application is shown;
[0023] Figure 3 A schematic diagram of the rotating component structure of this application is shown;
[0024] Figure 4 A schematic diagram of the extrusion assembly structure of this application is shown;
[0025] Figure 5 A schematic diagram of the separate component structure of this application is shown;
[0026] Figure 6 This application shows Figure 3 A schematic diagram of the enlarged portion of the structure at point A in the middle;
[0027] List of reference numerals
[0028] 1. Airframe;
[0029] 2. Feeding assembly; 201. Feed hopper; 202. Top filter frame;
[0030] 3. Rotating assembly; 301. Rotating frame; 302. Connecting cylinder; 303. Drive motor; 304. Discharge hole;
[0031] 4. Extrusion assembly; 401. Fixed shaft; 402. Extrusion block;
[0032] 5. Separation assembly; 501. External frame; 502. Separation plate; 503. Connecting rod;
[0033] 6. Filter assembly; 601. Filter frame; 602. Brush plate;
[0034] 7. Auxiliary components; 701. Auxiliary frame; 702. Discharge plate;
[0035] 8. Material cutting plate. Detailed Implementation
[0036] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the described embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.
[0037] Example 1: Please refer to Figures 1 to 6 :
[0038] This utility model discloses a granulation machine for pharmaceutical granulation, comprising: a machine frame 1; a rotating assembly 3 rotatably mounted inside the machine frame 1; a feeding assembly 2 mounted at the upper end of the rotating assembly 3; an extrusion assembly 4 disposed inside the rotating assembly 3 at the bottom of the feeding assembly 2; the bottom of the extrusion assembly 4 fixed to the bottom of the machine frame 1; a filter assembly 6 disposed on the upper outer side of the rotating assembly 3; a filter frame 601 disposed at the upper chamfer of the rotating assembly 3; the filter frame 601 is configured as a mesh frame; and a brush plate is mounted at the bottom of the separation plate 502 of the separation assembly 5 at the position of the filter frame 601. 602. After the drug particles pass through the beveled corner of the rotating component 3 and are directed toward the filter frame 601, the mesh structure of the filter frame 601 will filter them, allowing the filter frame 601 to separate the drug particles from some of the powder. The brush plate 602 provided at the separation component 5 allows the drug particles in the filter frame 601 to be better discharged from the feed plate 8. An auxiliary component 7 is installed at the bottom of the machine frame 1. The feed plate 8 is installed on the right side of the machine frame 1 corresponding to the filter component 6. The separation component 5 is installed at the feed plate 8 of the machine frame 1. The end of the separation component 5 contacts the upper outer wall of the rotating component 3.
[0039] In this embodiment of the disclosure, such as Figure 3 Figure 4 As shown, the feed hopper 201 of the feeding assembly 2 is configured as a funnel-shaped structure. A top filter frame 202 is snapped into the inside of the feed hopper 201. The top filter frame 202 is configured as a mesh frame structure. The funnel shape of the feed hopper 201 allows the feed hopper 201 to better consolidate the powder when it is poured in. The top filter frame 202 installed inside the feed hopper 201 allows the mesh frame structure of the top filter frame 202 to filter out some impurities, which facilitates better granulation of the powder in the subsequent process.
[0040] In this embodiment of the disclosure, such as Figure 3 As shown, the rotating frame 301 of the rotating assembly 3 is rotatably mounted on the machine frame 1. A drive motor 303 is installed on one side of the bottom of the rotating frame 301. The drive motor 303 meshes with the bottom of the rotating frame 301. The rotating assembly 3 is set as the main moving part of the device, while the extrusion assembly 4 is fixed. The rotating frame 301 is set to be rotatably mounted so that when the drive motor 303 drives the rotating frame 301, the rotating assembly 3 rotates as a whole, which facilitates the subsequent extrusion and granulation of the medicine powder in the rotating assembly 3 through the extrusion assembly 4.
[0041] In this embodiment of the disclosure, such as Figure 6As shown, the top corners of the rotating frame 301 are chamfered, and a connecting cylinder 302 is provided at the top of the rotating frame 301. The bottom of the connecting cylinder 302 is cylindrical, and a discharge hole 304 is provided on the outer wall of the bottom of the connecting cylinder 302. First, the top edge of the rotating frame 301 is chamfered so that the top of the rotating frame 301 can slide the granules outward better through the chamfered structure. The bottom of the connecting cylinder 302 is conical so that the bottom of the connecting cylinder 302 has a more stable effect when granulating the powder through the discharge hole 304.
[0042] In this embodiment of the disclosure, such as Figure 4 As shown, the fixed shaft 401 of the extrusion assembly 4 is fixed at the bottom of the machine frame 1. An extrusion block 402 is provided on the top of the fixed shaft 401. The extrusion block 402 is placed inside the connecting cylinder 302 of the rotating assembly 3. The extrusion block 402 is set as a volute block structure. After the powder enters the position of the extrusion block 402 inside the connecting cylinder 302, the extrusion assembly 4 is fixed on the machine frame 1 by the fixed shaft 401. The rotating assembly 3 will rotate. At this time, the powder will be extruded by the volute structure of the extrusion block 402 onto the inner wall of the connecting cylinder 302, so that the powder can be discharged from the discharge hole 304, thus achieving the granulation effect of the powder.
[0043] In this embodiment of the disclosure, such as Figure 5 As shown, the outer frame 501 of the separation component 5 is fixed to the outer wall of the machine frame 1 near the feeding plate 8. A separation plate 502 is hinged on the outer frame 501. The end of the separation plate 502 contacts the conical outer wall of the connecting cylinder 302 of the rotating component 3. A connecting rod 503 is installed between the separation plate 502 and the outer frame 501. The end of the separation plate 502 is set to be tightly attached to the outer wall of the connecting cylinder 302, so that the rotating connecting cylinder 302 contacts the end of the separation plate 502. This allows the drug particles extending from the discharge hole 304 to be separated by the separation plate 502, thus completing the granulation of the drug powder. The connecting rod 503 installed between the outer frame 501 and the separation plate 502 allows the separation plate 502 to better fit the outer wall of the connecting cylinder 302 for use.
[0044] In this embodiment of the disclosure, such as Figure 2 As shown, the auxiliary frame 701 of the auxiliary component 7 is set at the bottom of the filter component 6 inside the machine frame 1. The auxiliary frame 701 is set in an inclined position, and a discharge plate 702 is set at the outer end of the bottom position of the auxiliary frame 701. The auxiliary frame 701 is set at the bottom of the filter component 6. The inclined auxiliary frame 701 can guide the powder to be discharged. The discharge plate 702 at the bottom of the auxiliary frame 701 is convenient for external tools to collect.
[0045] The working principle of this embodiment is as follows: When in use, the medicine powder is poured directly into the feeding component 2, and then the medicine powder falls into the rotating component 3 at the bottom of the feeding component 2, so that the medicine powder comes into contact with the extrusion component 4. The rotating component 3 will cause the medicine powder to be squeezed out from the discharge hole 304 through the extrusion component 4. At this time, the separation component 5 is closely attached to the outer end of the discharge hole 304. The rotating component 3 will cause the separation component 5 to peel off the protruding medicine powder, so that the medicine powder forms medicine particles. The medicine particles will slide to the filter component 6. The filter component 6 will filter the medicine particles and separate the medicine particles from some of the powder. The powder will be discharged from the auxiliary component 7, while the medicine particles will be discharged through the feed plate 8.
[0046] The following points should be noted in this article:
[0047] 1. The accompanying drawings of the embodiments disclosed herein only relate to the structures involved in the embodiments disclosed herein; other structures can be referred to in general design.
[0048] 2. Where there is no conflict, the embodiments of this disclosure and the features in the embodiments can be combined with each other to obtain new embodiments.
[0049] The above are merely specific embodiments of this disclosure, but the scope of protection of this disclosure is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the scope of the technology disclosed in this disclosure should be included within the scope of protection of this disclosure. Therefore, the scope of protection of this disclosure should be determined by the scope of the claims.
Claims
1. A granulation machine for pharmaceutical granulation, comprising: A frame (1) is provided; a rotating assembly (3) is rotatably installed inside the frame (1). The rotating assembly (3) has a feeding assembly (2) installed at its upper end, and a pressing assembly (4) is provided inside the rotating assembly (3) at the bottom of the feeding assembly (2). The bottom of the pressing assembly (4) is fixed to the bottom of the frame (1). A filtering assembly (6) is provided on the outer side of the upper end of the rotating assembly (3), and the filter frame (601) of the filtering assembly (6) is located at the chamfered edge of the upper end of the rotating assembly (3). The filter frame (601) is set in a mesh frame shape. The bottom of the separation plate (502) of the separation component (5) is equipped with a brush plate (602) at the position of the filter frame (601). An auxiliary component (7) is installed at the position of the body frame (1) at the bottom of the filter component (6). A feeding plate (8) is installed on the right side of the body frame (1) corresponding to the filter component (6). The separation component (5) is installed at the feeding plate (8) of the body frame (1). The end of the separation component (5) contacts the upper outer wall of the rotating component (3).
2. The granulation machine for pharmaceutical granulation according to claim 1, characterized in that, The feeding hopper (201) of the feeding assembly (2) is configured as a funnel-shaped structure, and a top filter frame (202) is snapped into the internal position of the feeding hopper (201). The top filter frame (202) is configured as a mesh frame structure.
3. The granulation machine for pharmaceutical granulation according to claim 1, characterized in that, The rotating frame (301) of the rotating assembly (3) is rotatably mounted on the machine frame (1). A drive motor (303) is installed on one side of the bottom of the rotating frame (301), and the drive motor (303) meshes with the bottom of the rotating frame (301).
4. A granulation machine for pharmaceuticals according to claim 3, characterized in that, The top corners of the rotating frame (301) are chamfered, and a connecting cylinder (302) is provided at the top of the rotating frame (301). The bottom of the connecting cylinder (302) is cylindrical, and a discharge hole (304) is provided on the bottom outer wall of the connecting cylinder (302).
5. A granulation machine for pharmaceutical granulation according to claim 1, characterized in that, The fixed shaft (401) of the extrusion assembly (4) is fixed at the bottom of the machine frame (1). An extrusion block (402) is provided on the top of the fixed shaft (401). The extrusion block (402) is placed inside the connecting cylinder (302) of the rotating assembly (3). The extrusion block (402) is configured as a volute block structure.
6. A granulation machine for pharmaceutical granulation according to claim 1, characterized in that, The outer frame (501) of the separation component (5) is fixed on the outer wall of the machine frame (1) near the unloading plate (8). A separation plate (502) is hinged on the outer frame (501). The end of the separation plate (502) contacts the conical outer wall of the connecting cylinder (302) of the rotating component (3). A connecting rod (503) is installed between the separation plate (502) and the outer frame (501).
7. A granulation machine for pharmaceuticals according to claim 1, characterized in that, The auxiliary frame (701) of the auxiliary component (7) is located at the bottom of the filter component (6) inside the machine frame (1). The auxiliary frame (701) is inclined, and a discharge plate (702) is provided at the outer end of the bottom position of the auxiliary frame (701).