Inclined placing rack for reagent bottles for cell culture

By designing an inclined placement rack for reagent bottles for cell culture, the problem of inconvenience in tilting the reagent bottles is solved, a stable and flexible operation process is achieved, the risk of contamination is reduced, and it is suitable for cell culture operations.

CN223475078UActive Publication Date: 2025-10-28HENAN JINTAI BIOTECH
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Patent Information

Application Number
CN202422997765.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-05
Publication Date
2025-10-28
Estimated Expiration
2034-12-05

AI Technical Summary

Technical Problem

During the cell culture process, it is inconvenient to place the reagent bottles at an angle, which leads to inconvenient operation and increased risk of contamination. Especially when multiple bottles of reagents need to be operated, it is difficult for a single operator to keep the reagent bottles in an inclined state.

Method used

A tilted placement rack for reagent bottles for cell culture is designed. The rack is equipped with symmetrical placement slopes and placement grooves. Combined with the clamping assembly, the stable tilted placement of the reagent bottles is achieved. The cooperation of the transmission mechanism and the clamping plate ensures the stability and flexible operation of the reagent bottles in the placement groove.

Benefits of technology

It improves the flexibility and efficiency of reagent bottle operation, reduces the risk of contamination, simplifies the single-person operation process, is low-cost and reusable.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides an inclined placing rack for reagent bottles for cell culture. The inclined placement rack for the reagent bottles for cell culture comprises a rack body, wherein two placement inclined planes which are bilaterally symmetrical in the vertical direction are arranged on the rack body; a placing groove extending in the inclination direction of the placing inclined surface is formed in each placing inclined surface; the placing grooves are used for placing reagent bottles. The placement groove extends in the inclined direction of the placement inclined surface, so that the placement groove is also inclined, and when the reagent bottle is placed in the placement groove, the placement groove enables the reagent bottle to be in an inclined state. Therefore, during single-person operation, uncovered reagent bottles can be obliquely placed in the placing grooves of the frame body, other operations can be continuously carried out by free hands, the bottle caps do not need to be repeatedly opened, and the pollution risk is reduced. And the convenience and efficiency of related test operation are greatly improved.
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Description

Technical Field

[0001] This utility model relates to the field of cell culture equipment technology, and in particular to a tilting rack for cell culture reagent bottles. Background Technology

[0002] Cell culture procedures are performed in a clean bench, requiring strict aseptic techniques to prevent contamination. During cell resuscitation, culture, passage, medium change, and cryopreservation, reagents such as culture medium, trypsin, and physiological saline need to be added to the culture flasks. To prevent contamination, opened reagent bottles need to be tilted. Without a suitable rack, the bottles must be kept tilted by hand, making single-person operation inconvenient; the caps must be closed before proceeding. If the number of cultured cells is large, repeated opening and closing is not only cumbersome but also increases the risk of contamination, affecting the experiment. In summary, retrieving reagents from flasks during cell culture is inconvenient. Therefore, a suitable rack for tilting reagent bottles used in cell culture is needed to solve these problems. Utility Model Content

[0003] In view of the above problems, this utility model is proposed to provide a tilting rack for cell culture reagent bottles that overcomes or at least partially solves the above problems, which can solve the problem of inconvenient access to reagents in reagent bottles in current cell culture, and achieve the effect of improving the flexibility and efficiency of operating reagent bottles on the rack.

[0004] Specifically, this utility model provides a tilting rack for cell culture reagent bottles, which includes:

[0005] The frame has two symmetrical placement slopes along the vertical direction; each placement slope has a placement groove extending along the inclined direction of the placement slope; the placement groove is used to place the reagent bottle.

[0006] Optionally, the tilt rack for cell culture reagent bottles also includes:

[0007] Multiple clamping components are mounted on the frame, each clamping component corresponding to a placement slot, and the clamping components are used to clamp the reagent bottle when the reagent bottle is placed in the corresponding placement slot.

[0008] Optionally, the clamping assembly includes a first clamping plate, a second clamping plate, a tray, and a transmission mechanism;

[0009] The tray is disposed in the placement slot and can be slidably disposed along the length direction of the placement slot;

[0010] The first clamping plate and the second clamping plate are symmetrically arranged about the placement slot; the first clamping plate and the second clamping plate are slidably disposed on the frame in the left and right direction;

[0011] The pallet is connected to the first clamping plate and the second clamping plate via the transmission mechanism, so that the first clamping plate and the second clamping plate move closer or further apart when the pallet slides.

[0012] Optionally, the transmission mechanism includes a transmission gear, a first rack, a second rack, a tray rack, and a return spring;

[0013] The transmission gear is rotatably mounted on the frame; the first rack and the second rack are symmetrically arranged around the center of the transmission gear and both mesh with the transmission gear; the first rack is fixedly connected to the first clamping plate; the second rack is fixedly connected to the second clamping plate.

[0014] The tray rack extends along the length of the placement groove and is slidably disposed; the tray rack is fixedly connected to the tray; the return spring is disposed below the tray rack and is used to compress and store force when the tray rack moves downward.

[0015] Optionally, an installation cavity is provided below the placement slope; the placement slope is also provided with a first transverse groove and a second transverse groove extending in the left-right direction and communicating with the installation cavity; the first transverse groove and the second transverse groove are respectively located on the left and right sides of the placement groove;

[0016] The first clamping plate extends a first connecting rod towards the mounting cavity; the first connecting rod is inserted into the first transverse groove and fixedly connected to the first rack; the second clamping plate extends a second connecting rod towards the mounting cavity; the second connecting rod is inserted into the second transverse groove and fixedly connected to the second rack.

[0017] The placement slot is provided with a sliding groove that communicates with the mounting cavity; the tray rack is slidably inserted into the sliding groove; the tray is fixedly connected to the tray rack through a connecting block; the return spring is disposed at the bottom of the sliding groove.

[0018] Optionally, the upper surface of the tray is an arc-shaped concave surface.

[0019] Optionally, both the first clamping plate and the second clamping plate are arc-shaped plates coaxial with the placement groove.

[0020] This invention relates to a tilting rack for cell culture reagent bottles. The rack has a frame with tilting surfaces. Each tilting surface has at least one placement slot. Each slot can hold one reagent bottle. The two tilting surfaces are symmetrically arranged in a "V" shape, allowing the reagent bottle to be positioned inside the two tilting surfaces, thus improving safety during placement. The placement slots extend along the tilting direction of the tilting surfaces, ensuring they are also tilted. When a reagent bottle is placed in a slot, the slot keeps the bottle tilted. Therefore, during single-person operation, an open reagent bottle can be tilted and placed in the slot, freeing the hand to perform other operations without repeatedly opening the cap, reducing the risk of contamination. This significantly improves the convenience and efficiency of related experimental operations. It is simple, versatile, low-cost, and reusable.

[0021] Furthermore, during the operation using the reagent bottle placement slot, the reagent bottle is opened, the cap is removed, the required reagent is taken with a pipette, and the bottle is tilted and placed on the support. This allows for continued reagent addition. After one bottle is added, the reagent is taken from the placement slot for the next bottle. The tilted reagent bottle placement support has advantages such as ease of use, cost savings, and reusability, making it suitable for widespread application in cell culture operations.

[0022] The above and other objects, advantages and features of this utility model will become more apparent to those skilled in the art from the following detailed description of specific embodiments of this utility model in conjunction with the accompanying drawings. Attached Figure Description

[0023] The following sections will describe some specific embodiments of the present invention in a detailed manner by way of example and not limitation, with reference to the accompanying drawings. The same reference numerals in the drawings denote the same or similar parts or components. Those skilled in the art should understand that these drawings are not necessarily drawn to scale. In the drawings:

[0024] Figure 1 This is a schematic structural diagram of a tilting rack for cell culture reagent bottles according to an embodiment of the present invention;

[0025] Figure 2 This is a schematic partial structural diagram of a tilting rack for cell culture reagent bottles according to an embodiment of the present invention;

[0026] Figure 3 This is a schematic internal structure diagram of a tilting rack for cell culture reagent bottles according to an embodiment of the present invention;

[0027] Figure 4 yes Figure 3 A partial enlarged view of point A in the middle;

[0028] Figure 5 This is a schematic structural diagram of the transmission mechanism in a tilting rack for cell culture reagent bottles according to an embodiment of the present invention;

[0029] Figure 6 This is a schematic partial structural diagram of a tilting rack for cell culture reagent bottles according to an embodiment of the present invention.

[0030] In the diagram: 100, frame; 110, placement ramp; 120, placement slot; 130, mounting cavity; 140, first transverse slot; 150, second transverse slot; 160, sliding slot; 200, clamping assembly; 210, first clamping plate; 211, first connecting rod; 220, second clamping plate; 221, second connecting rod; 230, tray; 231, connecting block; 300, transmission mechanism; 310, transmission gear; 320, first rack; 330, second rack; 340, tray rack; 350, return spring. Detailed Implementation

[0031] The following reference Figures 1 to 6 This invention describes a tilting rack for reagent bottles used in cell culture, according to embodiments of the present invention. In this description, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined with "first" or "second" may explicitly or implicitly include at least one of that feature, that is, include one or more of that feature. In the description of the present invention, "a plurality of" means at least two, such as two, three, etc., unless otherwise explicitly specified. When a feature "includes or contains" one or more of the features it encompasses, unless otherwise specifically described, this indicates that other features are not excluded and may be further included.

[0032] Unless otherwise expressly specified and limited, the terms "set," "install," "connect," "link," "fix," and "couple" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art should be able to understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0033] Furthermore, in the description of this embodiment, "above" or "below" the second feature can include direct contact between the first and second features, or it can include contact between the first and second features through another feature between them. That is, in the description of this embodiment, "above," "over," and "on top" of the second feature includes the first feature being directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," or "below" of the second feature can mean the first feature is directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0034] In the description of this embodiment, the terms "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of this utility model. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0035] Figure 1 This is a schematic diagram of a tilting rack for cell culture reagent bottles, such as... Figure 1 As shown, and refer to Figures 2 to 6 This utility model provides a tilting rack for cell culture reagent bottles. The tilting rack for cell culture reagent bottles includes a frame 100, on which two tilting surfaces 110 are provided symmetrically in the vertical direction. Each tilting surface 110 is provided with a placement groove 120 extending in the tilting direction of the tilting surface 110. The placement groove 120 is used to place reagent bottles.

[0036] Specifically, at least one placement slot 120 is provided on a placement ramp 110. Each placement slot 120 can be used to place a reagent bottle. To accommodate the structure of the reagent bottle, the cross-section of the placement slot 120 is generally semi-circular. Furthermore, the two placement ramps 110 are symmetrically arranged in a "V"-shaped ramp structure. This structure allows the reagent bottle to be located inside the two placement ramps 110, thereby improving the safety of the reagent bottle during placement. Furthermore, the placement slots 120 extend along the inclined direction of the placement ramps 110, ensuring that the placement slots 120 are also inclined, so that when the reagent bottle is placed in the placement slot 120, the placement slot 120 keeps the reagent bottle in an inclined state. Therefore, during single-person operation, the opened reagent bottle can be placed at an angle in the placement slot 120 of the frame 100, freeing up the hand to continue other operations without repeatedly opening the bottle cap, reducing the risk of contamination. This greatly improves the convenience and efficiency of related experimental operations. It is simple, versatile, low-cost, and reusable.

[0037] When using the reagent bottle placement slot 120, open the reagent bottle, remove the cap, use a pipette to take the required reagent, and then tilt the bottle onto the support. This allows for continued reagent addition. After adding one bottle, retrieve the reagent from the placement slot 120 for the next bottle. The tilting reagent bottle placement support offers advantages such as ease of use, cost-effectiveness, and reusability, making it suitable for widespread application in cell culture procedures.

[0038] In this embodiment, one inclined plane 110 has an angle of 40 degrees with the horizontal plane, and the other inclined plane 110 has an angle of 50 degrees with the horizontal plane. The height of one inclined plane 110 is 6.5 cm, and the height of the other inclined plane 110 is 5.5 cm.

[0039] In this embodiment, the bottom of the frame 100 is flat, which improves the stability of the frame 100 during placement. Furthermore, the placement slots 120 of the two placement ramps 110 are staggered.

[0040] In some embodiments of this utility model, such as Figure 2 and Figure 3 As shown, the tilting rack for cell culture reagent bottles also includes multiple clamping components 200, which are mounted on the rack body 100. Each clamping component 200 corresponds to a placement slot 120. The clamping components 200 are used to clamp the reagent bottles when they are placed in their corresponding placement slots 120.

[0041] Specifically, each clamping assembly 200 is used to clamp a reagent bottle within a placement slot 120, thereby further increasing the stability of the reagent bottle placed within the placement slot 120.

[0042] In some embodiments of this utility model, such as Figure 3 and Figure 4 As shown, the clamping assembly 200 includes a first clamping plate 210, a second clamping plate 220, a tray 230, and a transmission mechanism 300. The tray 230 is disposed within the placement groove 120 and is slidably disposed along the length of the placement groove 120. The first clamping plate 210 and the second clamping plate 220 are symmetrically arranged about the left and right sides of the placement groove 120, and are slidably disposed on the frame 100 in the left and right directions. The tray 230 is connected to the first clamping plate 210 and the second clamping plate 220 through the transmission mechanism 300, so that when the tray 230 slides, the first clamping plate 210 and the second clamping plate 220 move closer or further apart.

[0043] Specifically, the left and right directions of the placement slot 120 are as follows: Figure 3 The left-right direction is shown in the diagram. Further, the tray 230 contacts the bottom of the reagent bottle. Further, when the tray 230 moves downwards, the transmission mechanism 300 causes the first clamping plate 210 and the second clamping plate 220 to move closer together, and vice versa. When a medicine bottle is placed on the tray 230, the tray 230 moves downwards under the weight of the medicine bottle, thereby causing the first clamping plate 210 and the second clamping plate 220 to move closer together to clamp the medicine bottle.

[0044] In some embodiments of this utility model, such as Figure 4 and Figure 5 As shown, the transmission mechanism 300 includes a transmission gear 310, a first rack 320, a second rack 330, a tray rack 340, and a return spring 350. The transmission gear 310 is rotatably mounted on the frame 100. The first rack 320 and the second rack 330 are symmetrically arranged around the center of the transmission gear 310 and both mesh with the transmission gear 310. The first rack 320 is fixedly connected to the first clamping plate 210, and the second rack 330 is fixedly connected to the second clamping plate 220. The tray rack 340 extends along the length of the placement groove 120 and is slidably mounted. The tray rack 340 is fixedly connected to the tray 230, and the return spring 350 is located below the tray rack 340 for compressing and storing force when the tray rack 340 moves downward.

[0045] Specifically, both the first rack 320 and the second rack 330 extend in the left-right direction and are parallel to each other. Since both the first rack 320 and the second rack 330 mesh with the transmission gear 310 and are symmetrically arranged about the center of the transmission gear 310, when the transmission gear 310 rotates, it always drives the first rack 320 and the second rack 330 to move relative to each other. That is, when the transmission gear 310 rotates in the first direction, it drives the first rack 320 and the second rack 330 to move relative to each other, causing the first clamping plate 210 and the second clamping plate 220 to move closer together; when the transmission gear 310 rotates in the second direction, it drives the first rack 320 and the second rack 330 to move relative to each other, causing the first clamping plate 210 and the second clamping plate 220 to move away from each other. Therefore, when the tray 230 moves downward, it drives the transmission gear 310 to rotate in the first direction via the tray rack 340; when the tray 230 moves upward, it drives the transmission gear 310 to rotate in the second direction via the tray rack 340.

[0046] Furthermore, in the initial state, the tray 230 and the bottom of the placement slot 120 are spaced apart. Furthermore, the return spring 350 allows the tray 230 to be in a preset position when not under pressure, with the tray rack 340 positioned at this preset position. This preset position maximizes the distance between the first clamping plate 210 and the second clamping plate 220, and in this state, the distance between the first clamping plate 210 and the second clamping plate 220 is greater than the width of the placement slot 120, thus facilitating the placement of reagent bottles within the placement slot 120. Furthermore, when the reagent bottle is removed from the placement slot 120, the return spring 350 releases its elastic force and pushes the tray 230 upwards, thereby distancing the first clamping plate 210 and the second clamping plate 220 from each other, facilitating the removal of the reagent bottle from the placement slot 120.

[0047] Furthermore, the transmission arrangement of the transmission gear 310, the first rack 320, the second rack 330, and the tray rack 340 ensures that the clamping force of the first clamping plate 210 and the second clamping plate 220 is positively correlated with the downward movement distance of the tray 230. Since the downward movement distance of the tray 230 is positively correlated with the weight of the reagent bottle, the greater the weight of the reagent bottle, the greater the clamping force exerted by the first clamping plate 210 and the second clamping plate 220 on the reagent bottle within the placement slot 120.

[0048] In some embodiments of this utility model, such as Figures 4 to 6 As shown, a mounting cavity 130 is provided below the placement slope 110. The placement slope 110 is also provided with a first horizontal groove 140 and a second horizontal groove 150 extending in the left and right direction and communicating with the mounting cavity 130. The first horizontal groove 140 and the second horizontal groove 150 are located on the left and right sides of the placement groove 120, respectively.

[0049] A first connecting rod 211 extends from the first clamping plate 210 toward the mounting cavity 130; the first connecting rod 211 is inserted into the first transverse groove 140 and fixedly connected to the first rack 320. A second connecting rod 221 extends from the second clamping plate 220 toward the mounting cavity 130. The second connecting rod 221 is inserted into the second transverse groove 150 and fixedly connected to the second rack 330.

[0050] The placement groove 120 is provided with a sliding groove 160 that communicates with the mounting cavity 130. The tray rack 340 is slidably inserted into the sliding groove 160. The tray 230 is fixedly connected to the tray rack 340 through the connecting block 231. The return spring 350 is provided at the bottom of the sliding groove 160.

[0051] Specifically, the first transverse groove 140 and the second transverse groove 150 are used to install the first connecting rod 211 and the second connecting rod 221 respectively, thereby increasing the stability of the first clamping plate 210 and the second clamping plate 220 in sliding left and right. Further, the sliding groove 160 defines a sliding track for the tray rack 340, thereby constraining the sliding direction of the pusher rack. Further, the upper end of the return spring 350 is fixedly connected to the lower end of the tray rack 340, and the lower end is fixedly connected to the bottom of the sliding groove 160.

[0052] In some embodiments of this utility model, such as Figure 5 As shown, the upper surface of tray 230 is a concave arc. Specifically, since the bottom of reagent bottles is mostly circular, the concave arc of tray 230 can improve the stability of reagent bottles placed in the placement slot 120.

[0053] In some embodiments of this utility model, such as Figure 4 and Figure 5 As shown, both the first clamping plate 210 and the second clamping plate 220 are arc-shaped plates coaxial with the placement groove 120. Specifically, the first clamping plate 210 and the second clamping plate 220 have the same structure. Preferably, the diameters of the circles corresponding to the placement groove 120 and the first clamping plate 210 and the second clamping plate 220 are the same. Furthermore, the arc-shaped design of the first clamping plate 210 and the second clamping plate 220 increases the clamping area of ​​the reagent bottle, thereby further increasing the stability of the reagent bottle clamping.

[0054] Therefore, those skilled in the art should recognize that although many exemplary embodiments of the present invention have been shown and described in detail herein, many other variations or modifications conforming to the principles of the present invention can be directly determined or derived from the disclosure of the present invention without departing from the spirit and scope of the present invention. Therefore, the scope of the present invention should be understood and recognized as covering all such other variations or modifications.

Claims

1. A tilting rack for reagent bottles used in cell culture, characterized in that, include: The frame has two symmetrical placement slopes along the vertical direction; each placement slope has a placement groove extending along the inclined direction of the placement slope; the placement groove is used to place the reagent bottle.

2. The tilting rack for cell culture reagent bottles according to claim 1, characterized in that, Also includes: Multiple clamping components are mounted on the frame, each clamping component corresponding to a placement slot, and the clamping components are used to clamp the reagent bottle when the reagent bottle is placed in the corresponding placement slot.

3. The tilting rack for cell culture reagent bottles according to claim 2, characterized in that, The clamping assembly includes a first clamping plate, a second clamping plate, a tray, and a transmission mechanism; The tray is disposed in the placement slot and can be slidably disposed along the length direction of the placement slot; The first clamping plate and the second clamping plate are symmetrically arranged about the placement slot; the first clamping plate and the second clamping plate are slidably disposed on the frame in the left and right direction; The pallet is connected to the first clamping plate and the second clamping plate via the transmission mechanism, so that the first clamping plate and the second clamping plate move closer or further apart when the pallet slides.

4. The tilting rack for cell culture reagent bottles according to claim 3, characterized in that, The transmission mechanism includes a transmission gear, a first rack, a second rack, a tray rack, and a return spring; The transmission gear is rotatably mounted on the frame; the first rack and the second rack are symmetrically arranged around the center of the transmission gear and both mesh with the transmission gear; the first rack is fixedly connected to the first clamping plate; the second rack is fixedly connected to the second clamping plate. The tray rack extends along the length of the placement groove and is slidably disposed; the tray rack is fixedly connected to the tray; the return spring is disposed below the tray rack and is used to compress and store force when the tray rack moves downward.

5. The tilting rack for cell culture reagent bottles according to claim 4, characterized in that, A mounting cavity is provided below the placement slope; a first horizontal groove and a second horizontal groove are also provided on the placement slope, extending in the left and right direction and communicating with the mounting cavity; the first horizontal groove and the second horizontal groove are respectively located on the left and right sides of the placement groove; The first clamping plate extends a first connecting rod towards the mounting cavity; the first connecting rod is inserted into the first transverse groove and fixedly connected to the first rack; the second clamping plate extends a second connecting rod towards the mounting cavity; the second connecting rod is inserted into the second transverse groove and fixedly connected to the second rack. The placement slot is provided with a sliding groove that communicates with the mounting cavity; the tray rack is slidably inserted into the sliding groove; the tray is fixedly connected to the tray rack through a connecting block; the return spring is disposed at the bottom of the sliding groove.

6. The tilting rack for cell culture reagent bottles according to claim 3, characterized in that, The upper surface of the tray is an arc-shaped concave surface.

7. The tilting rack for cell culture reagent bottles according to claim 3, characterized in that, Both the first clamping plate and the second clamping plate are arc-shaped plates coaxial with the placement groove.