Tissue separating and cleaning integrated device

Abstract

The utility model discloses a tissue separation and cleaning integrated device, which belongs to the technical field of experimental equipment and comprises a control table, a tissue separation operation table and a tissue cleaning device. The control console comprises a first control console surface and a second control console surface which are respectively used for regulating and controlling the tissue separation console and the tissue cleaning device. The tissue separation operation table is provided with a separation platform and a transparent isolation cover with an ultraviolet disinfection lamp, the cover is provided with a separation window, the bottom is provided with a semiconductor cooler for temperature control, and the platform is further provided with an electronic scale. The tissue cleaning device comprises a tissue containing mesh strainer, a low-temperature tissue storage box, an elution plate with a sliding rail at the bottom and a support with a supporting column and a plate frame. The elution plate is provided with a plurality of groups of working grooves containing washing grooves, dewatering grooves and storage grooves, magnetic stirrers are arranged on the strainer and the groove bottoms, and cleaning and dewatering are achieved through a magnetic field. The dewatering pipe is of a three-layer structure, the disc frame can be lifted, and electromagnetic strips or electromagnetic blocks are arranged on the lower surface to suck the strainer. The device can efficiently complete tissue cleaning and separation, is convenient to operate and reduces pollution.

Description

Technical Field

[0001] This utility model belongs to the field of experimental equipment technology, specifically relating to an integrated device for tissue separation and cleaning. Background Technology

[0002] Animal experiments play a crucial role in life science research. Most animal experiments, such as Western blotting (WB), PCR, qPCR, and COIP, require cleaning animal tissues to remove solid contaminants and organic matter such as dust, fur, and blood, eliminating experimental interference. Furthermore, when animal tissues are sampled at room temperature, proteins, RNA, and dsDNA are easily degraded and denatured, and enzymes are easily inactivated; therefore, operations must be performed at low temperatures. Currently, most laboratory experiments involving low temperatures are conducted on ice. However, prolonged operation time causes the ice to melt into water, complicating the experiment and making it impossible to maintain a consistently low temperature environment. To maintain a low-temperature environment for an extended period, Chinese patent application number CN201821983737.X discloses a multifunctional low-temperature biological operating table. This device maintains the low temperature by setting up a low-temperature stage inside a transparent sterilization hood. It adopts a water-cooling heat dissipation mode, with a water-cooling head embedded in the bottom of the low-temperature stage. One end of the water-cooling head is embedded in the low-temperature stage, and the other end is connected to a water pipe. Cooling is achieved by attaching a semiconductor cooling chip above the water-cooling head at the end of the low-temperature stage, and a heat-conducting aluminum plate is placed on top of it, thus obtaining a biological operating table that can maintain a low temperature.

[0003] The aforementioned utility model patent solves the technical problem of low-temperature operation in the laboratory. However, animal experiments still involve solid contaminants such as dust, fur, and blood, as well as interfering factors such as organic matter. Therefore, the separated tissues need to be cleaned before subsequent experiments. Regarding tissue cleaning, commonly used methods in animal experiments include cardiac perfusion and superior vena cava incision and bloodletting. The specific procedure for cardiac perfusion involves washing away blood from the blood vessels with physiological saline or PBS before taking tissue samples for testing, thereby eliminating the influence of blood on subsequent immunofluorescence, Western blotting, and other experiments. Superior vena cava incision and bloodletting involves first anesthetizing the animal, fixing it on the operating table, injecting heparin for systemic heparinization, opening the chest, making small incisions in the left and right superior vena cava to release blood, and injecting pre-cooled heparinized physiological saline from the aortic arch until the blood in the heart is completely flushed out, thus eliminating the influence of blood on subsequent immunofluorescence, Western blotting, and other experiments. To address this, Chinese Patent Application No. CN201821652350.6 discloses a multifunctional cryogenic biological operating table. This operating table uses a temperature control device with a built-in temperature sensor to regulate the temperature, providing a continuous low-temperature environment for experiments. It also features tissue sample cleaning holes on the operating table body. This device cleans tissues by placing them into the cleaning holes for washing and then draining the waste liquid from the bottom. However, in animal experiments, which often require multiple sets of tissue washing, the above method necessitates cleaning and disinfecting the sample cleaning holes after each waste liquid discharge, significantly delaying the experimental process. Furthermore, the cleaned tissues often retain excessive cleaning liquid, requiring further water absorption before subsequent experiments.

[0004] In summary, based on the traditional operating methods and the two utility model devices mentioned above, this application aims to provide a biological operating table that can provide a sterile and low-temperature environment, as well as enable tissue cleaning and easy replacement. It needs to have multiple functions such as sterilization, low temperature, washing and dehydration, effectively improving the experimental efficiency of the experimenter and efficiently eliminating experimental interference factors. Summary of the Invention

[0005] To achieve the above objectives, this utility model provides an integrated tissue separation and cleaning device. This device is divided into a tissue separation zone, a low-temperature waiting zone, and a tissue cleaning zone. A dehydration structure is added to the tissue cleaning zone to achieve automatic elution. The specific technical solution is as follows:

[0006] An integrated tissue separation and cleaning device, comprising a control console, a tissue separation operating table, and a tissue cleaning device;

[0007] The control console includes a first control surface for adjusting the tissue separation operating table and a second control surface for controlling the tissue cleaning device for cleaning and transfer. The control console is connected to the tissue separation operating table and the tissue cleaning device via electrical signals.

[0008] The tissue separation operating table includes a separation platform and a transparent isolation cover. The transparent isolation cover is fixedly installed on the separation platform as a base to form an independent operating space. An ultraviolet disinfection lamp is installed on the top of the transparent isolation cover, and a window is opened at the bottom of the side wall to facilitate tissue separation. The temperature inside the operating space is controlled by a semiconductor cooler installed at the bottom of the separation platform.

[0009] The base of the tissue cleaning device is equipped with a multi-linked magnetic stirrer. The upper end of the base is provided with a tissue container, a low-temperature tissue storage box, an elution plate, and a support. The tissue container is a tubular mesh strainer with a stir bar at the bottom. The elution plate is a horizontally movable elution plate with a slide rail 20 at the bottom and a working groove for elution. The low-temperature tissue storage box is a cavity fixedly installed in the shell of the second control panel, with the same height as the elution plate. The support includes a support column and a tray. The tray is installed above the elution plate by the support column and the tissue is picked up and put in by the adsorption mesh strainer in the guide groove of the support column.

[0010] Furthermore, the separation platform is also equipped with an electronic scale for weighing tissue blocks, and the function buttons of the electronic scale are located on the first control panel.

[0011] Furthermore, the window is located at the bottom of the side wall facing the first control panel, and the window cover is connected to the side wall of the transparent isolation cover by a snap-fit.

[0012] Furthermore, the washing and dehydrating plate is provided with multiple sets of working tanks, each set of working tanks including a row of washing tanks, a row of dehydrating tanks and a row of storage tanks, with the washing tanks, dehydrating tanks and storage tanks of each set of working tanks arranged alternately in the horizontal direction.

[0013] Furthermore, the top of the mesh is provided with a suction port that attracts the sampling electromagnetic block when it is energized.

[0014] Furthermore, the washing tank is equipped with a washing pipe, the dehydration tank is equipped with a dehydration pipe, and the storage tank is equipped with a covered EP pipe.

[0015] Furthermore, the dehydration tube has a three-layer structure, with the outer layer being a PVC material that can be autoclaved, the middle layer being a hollow structure, and a replaceable absorbent paper being placed inside the cavity. The inner layer of the tube wall is made of absorbent fiber material that prevents tissue adhesion.

[0016] Furthermore, the plate frame is raised and lowered by a cylinder, and an electromagnetic strip / block adapted to the working groove is installed on the lower surface of the plate frame.

[0017] Furthermore, the top cover of the low-temperature tissue storage box is provided with multiple round holes for placing EP tubes to temporarily store tissue blocks.

[0018] Furthermore, the bottom of the washing plate is provided with a slide rail, and the washing plate moves horizontally on the slide rail by pushing and pulling the telescopic rod.

[0019] The working principle of this utility model is as follows: A tissue separation and cleaning integrated device includes a control console (1), a tissue separation operating table (2), and a tissue cleaning device (4). First, the tissue is cut into pieces in the tissue separation operating table (2) which has a cooling effect after being irradiated by ultraviolet lamp (32). Multiple tissue pieces are placed into multiple tissue holding containers (41) composed of mesh strainers and placed in a washing tank (51) for synchronous washing by a multi-linked magnetic stirrer. Then, the washed mesh strainers are transferred to the dehydration tube (6) of the dehydration tank (52) and dehydrated by rotation under centrifugal action (this process is achieved by rotating the mesh strainers. The bottom of the mesh strainers and the bottom of the washing tank (51) and the dehydration tank (52) are equipped with mutually repulsive magnetic stirrers (91). When energized, the magnetic field is used to drive the mesh strainers placed in the tank to rotate in a circular motion for cleaning and dehydration. The specific operation is as follows:

[0020] Step 1: Before starting the experiment, turn on the main switch of the device. Adjust the temperature of the tissue separation worktable (2) to the required temperature by adjusting the temperature control key, then press the ultraviolet light switch to turn on the ultraviolet lamp (32), wait for 30 minutes for disinfection, press the ultraviolet light switch again to turn off the ultraviolet light, and turn on the lighting switch to start tissue separation.

[0021] Step 2: Observe the temperature display screen to see if the temperature reaches the required temperature for the experiment, and place the EP tube of the tissue to be separated into a low temperature tissue storage box (42) for storage.

[0022] Step 3: Turn on the electronic scale switch, push open the manual door, take out the EP tube of the tissue to be separated from the low-temperature tissue storage box (42), take out the tissue, and quickly place it on the separation platform (21) to perform the tissue separation operation. Before the separation process, you can press the zero button to make the scale reading zero. After placing the EP tube on the electronic scale, press the tare button to tare the weight of the EP tube. The experimenter takes the tissue to be separated, puts it into the tare EP tube, and weighs the tissue to the target weight. After the tissue separation is completed, put the separated target tissue into the corresponding EP tube and put it back into the low-temperature tissue storage box (42) for storage. After all tissue separation operations are completed, clean the separation platform (21), close the manual door, and press the electronic scale (22) switch to turn off the scale.

[0023] Step 4: Rotate the slide rail (20) knob of the washing plate (43) to the 'full out' position. The washing plate (43) will be completely dislodged to the right. Place the washing tube (7) and the dehydration tube (6) into the column with the word 'wash' and the column with the word 'dehydrate' on the washing plate (43) respectively. Place the capped EP tube into the column with the word 'EP'. Add an appropriate amount of physiological saline to the washing tube (7). Then, place the target tissue into multiple tissue strainers one by one. Then, place the multiple tissue strainers into the washing tube (7) containing physiological saline one by one. After the operation is completed, rotate the slide rail (20) knob of the washing plate (43). The washing plate (43) will return to its original position along the slide rail (20) under the pulling force of the telescopic rod (101).

[0024] Step 5: Select the washing time on the timer panel. Start the timer by rotating the base plate magnetic knob. Control the rotation speed of the tissue mesh strainer by rotating the base plate magnetic knob. When the preset time is reached, the timer button on the timer panel will flash. At this time, turn the base plate magnetic knob back to the initial position to stop tissue washing.

[0025] Step 6: Press the down button on the electromagnetic strip to move it down an appropriate distance. Then press the electromagnetic strip switch to turn it on, attracting the tissue mesh to the electromagnetic strip. Press the up button on the electromagnetic strip to return it to its original position. Rotate the slide rail (20) knob of the washing plate (43) to the 'wash' position. Move the washing plate (43) to the right a corresponding distance so that the column with the word 'wash' on the washing plate (43) is directly below the electromagnetic strip. Press the down button on the electromagnetic strip to move it down an appropriate distance. Press the electromagnetic strip switch again to remove the magnetic force of the electromagnetic strip, allowing the tissue mesh to enter the column with the word 'wash' on the washing plate (43). Select the dehydration time on the timer panel and start timing by rotating the bottom magnetic knob. When the preset time is reached, the timer button on the timer panel will flash. At this time, rotate the bottom magnetic knob back to the initial position to stop the tissue dehydration.

[0026] Step 7: Rotate the wash plate (43) slide rail (20) knob to the 'All Out' position, use sterile forceps to clamp the tissue from the 'Escape' tissue strainer into the 'EP' tube, and finally sort the EP tubes containing the tissue into the freezer box and put them in the refrigerator or conduct the corresponding experiments.

[0027] Compared with the prior art, the beneficial effects of this utility model are:

[0028] (1) The tissue separation device of this utility model is equipped with a constant low temperature base to ensure that the tissue is in a low temperature environment during tissue sampling, elution and storage, and to ensure that the tissue remains intact during operation and prevent the denaturation and degradation of substances in the tissue.

[0029] (2) The tissue separation workbench is also equipped with ultraviolet light to create a sterile environment;

[0030] (3) An electronic scale is provided in the upper left corner of the tissue processing platform to help the experimenter cut tissue of the desired weight;

[0031] (4) The tissue washing operation device of this utility model incorporates a magnetic rotation design in the tissue washing part. The elution leak rotates under the action of magnetic force, so that the tissue is completely washed away.

[0032] (5) This utility model incorporates an electromagnet design. When energized, the magnetic force generated causes the washout leak to be attracted upward and leave the tray. When the power is turned off, the magnetic force disappears and causes it to fall back into the tray, thus cleverly achieving the transfer of the washout leak.

[0033] (6) The tissue dehydration section incorporates a magnetic rotation and dehydration tube design, which is beneficial for tissue dehydration while ensuring tissue integrity.

[0034] (7) The mesh is equipped with many small-diameter holes, which is conducive to the penetration of washing liquid into the washing process and to the separation of tissue from washing liquid during dehydration; the dehydration tube is equipped with three layers: outer material, middle absorbent paper, and dehydration by capillary action; the inner layer of the tube wall is a PVC material layer that can be sterilized by high pressure, and has absorbent fiber material to prevent tissue adhesion during dehydration.

[0035] (8) The integrated tissue separation and cleaning device of this utility model creates a constant low temperature environment, ensures tissue integrity, reduces manpower consumption, prevents tissue contamination, and facilitates sample classification and temporary storage. Attached Figure Description

[0036] Figure 1 This is a schematic diagram of the structure of an integrated tissue separation and cleaning device according to the present invention;

[0037] Figure 2 This is a front view of an integrated tissue separation and cleaning device according to the present invention;

[0038] Figure 3 This is a schematic diagram of the tissue separation operating table of the integrated tissue separation and cleaning device of this utility model.

[0039] Figure 4 This is a schematic diagram illustrating the usage and operation of this utility model;

[0040] Figure 5 This is a schematic diagram of the washing plate of this utility model;

[0041] Figure 6 This is a schematic diagram of the support structure of this utility model;

[0042] Figure 7 This is a top view of the tissue cleaning device of this utility model;

[0043] Figure 8 This is the first usage state of the tissue cleaning device of this utility model;

[0044] Figure 9 This is the second usage state of the tissue cleaning device of this utility model;

[0045] Figure 10 This is the third usage state of the tissue cleaning device of this utility model;

[0046] Figure 11 This is an enlarged view of the working groove portion of this utility model;

[0047] Figure 12 This is a schematic diagram of the base structure of the tissue cleaning device of this utility model;

[0048] In the diagram, 1-control console; 11-first control console surface; 12-second control console surface; 2-tissue separation operating table; 21-tabletop; 22-electronic scale; 221-weight display screen ( Figure 1 (No markings in the text); 222-Temperature display screen; 3-First transparent isolation cover; 31-Window; 32-UV lamp; 4-Tissue washing device; 41-Tissue holding vessel; 42-Low temperature tissue storage box; 43-Eluting plate; 44-Support; 441-Support column; 4411-Guide groove; 4412-Connector; 442-Panel rack; 443-Hydraulic cylinder; 45-Second transparent isolation cover; 5-Working tank; 51-Washing tank; 52-Dehydration tank; 53-Placement tank; 6-Dehydration pipe; 7-Washing pipe; 8-EP pipe; 9-Multi-unit magnetic stirrer; 91-Stirring bar; 92-Magnet; 93-Motor; 94-Gear; 101-Telescopic rod; 102-Sampling electromagnetic block; 20-Slide rail. Detailed Implementation

[0049] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to specific embodiments and accompanying drawings. It should be understood that these descriptions are merely exemplary and not intended to limit the scope of this utility model. Furthermore, descriptions of well-known structures and technologies are omitted in the following description to avoid unnecessarily obscuring the concept of this utility model.

[0050] Example: This utility model discloses an integrated tissue separation and cleaning device, which includes a control console 1, a tissue separation operating table 2, and a tissue cleaning device 4.

[0051] The control console 1 includes a first control panel 11 and a second control panel 12. The first control panel 11 is used to regulate the operation of the tissue separation worktable 2. It is set on the base of the tissue separation worktable 2. The first control panel 1 is equipped with a main switch, a light switch (including an ultraviolet lamp 32 and a lighting lamp), a temperature control switch, and a switch for the electronic scale 22 (including a zeroing button and a tare button). The first control panel 1 is also equipped with a temperature display screen for displaying temperature and mass and a weight display screen 221 for the electronic scale 22. The second control panel 12 is used to control the tissue cleaning device 4 to perform cleaning and transfer operations. It is set on the base of the tissue cleaning device 4. It is equipped with a main switch for the tissue cleaning device 4, a knob for the slide rail 20 of the washing plate 43, a timer button, a magnetic knob, and control keys (up and down buttons) for the support 44. The control console 1 is connected to the tissue separation worktable 2 and the tissue cleaning device 4 via electrical signals.

[0052] The tissue separation workbench 2 includes a separation platform and a first transparent isolation cover 3. The separation platform includes a tabletop mounted on the base of the tissue separation workbench 2 and a cooling device mounted below the tabletop. The tabletop is made of a heat-conducting metal plate (preferably a heat-conducting aluminum plate). An electronic scale for measuring the weight of the separated tissue is embedded in the tabletop. The weight measured by the electronic scale is displayed on a weight display screen 221 on the first control tabletop 11 for easy recording by the experimental operator. The cooling device is a semiconductor cooler mounted at the bottom of the separation platform. The temperature sensor of the semiconductor cooler is located on the lower surface of the tabletop. The semiconductor cooler is connected to the signal output terminal of a temperature control switch. The temperature sensor converts the sensed temperature into an electrical signal and transmits it to the temperature display screen to display the temperature of the workbench surface, which is used to adjust the workbench surface temperature in real time. The first transparent isolation cover 3 is fixedly installed on the base of the tissue separation operating table 2 for fully enclosing the table surface of the tissue separation operating table 2. The top of the transparent isolation cover is equipped with an ultraviolet disinfection lamp and a lighting lamp, and the bottom of the side wall is provided with a window 31 to facilitate tissue separation. The window 31 is opened at the bottom of the side wall facing the first control table 11, and the window stop of the window 31 is connected to the side wall of the transparent isolation cover by a snap fastener.

[0053] like Figure 1-11 As shown, the tissue cleaning device 4 includes a tissue container 41, a low-temperature tissue storage box 42, an elution plate 43, and a support 44.

[0054] The low-temperature tissue storage box 42 is installed in the cavity of the second control panel 12 of the base of the tissue cleaning device 4. Ice is placed in the cavity to maintain the low temperature. After the ice melts, it is discharged through the drain port at the bottom of the box. The top cover of the low-temperature tissue storage box 42 is a detachable top cover. Several round holes for fitting EP tubes 8 are evenly opened on the top cover for placing EP tubes 8 containing tissue blocks.

[0055] like Figure 5 As shown, the washing plate 43 is a perforated plate with multiple sets of working grooves 5 evenly arranged on its upper surface. Each working groove 5 includes a washing groove 51, a dehydration groove 52, and a storage groove 53. Each set of working grooves 5 consists of alternating rows of washing grooves 51, dehydration grooves 52, and storage grooves 53. Each washing groove 51 includes several perforations, and the number of perforations in the dehydration grooves 52 and storage grooves 53 is the same as that in the washing grooves 51. The word "wash" is written on the front end of the washing groove 51, the word "dehydration" is written on the front end of the dehydration groove 52, and the letters "EP" are written on the front end of the storage groove 53. A slide rail 20 is provided at the bottom of the washing plate 43, which slides in conjunction with the bottom side wall of the washing plate 43. The side of the washing plate 43 near the tissue separation operating table 2 is connected to an electric telescopic rod 101, allowing the washing plate 43 to move horizontally within the slide rail 20 via the telescopic rod 101.

[0056] The washing tank 51 contains a replaceable washing tube 7, the size of which is adapted to the size of the washing tank 51. The washing tube 7 is placed in the washing tank 51 to hold washing solution (physiological saline) for cleaning the tissue block. The dehydration tank 52 contains a replaceable dehydration tube 6, which has a three-layer structure: an outer layer of autoclaved PVC material, a hollow cavity containing replaceable absorbent paper, and an inner wall made of absorbent fiber material to prevent tissue adhesion. The storage tray 53 contains an EP tube 8 for temporarily storing cleaned tissue, with a sealing cap at the top.

[0057] like Figure 6 As shown, the support 44 includes a support column 441 and a tray frame 442. The tray frame 442 is mounted above the washing plate 43 via the support column 441, and tissue is placed and removed by the adsorption mesh on the support column 441. The opposite surface of the support column 441 is provided with a guide groove 4411 for guiding the lifting and lowering of the tray frame 442. A strip-shaped protrusion is provided at the waist of the guide groove 4411 in the depth direction to engage with the groove of the connector 4412 to prevent the tray frame 442 from shifting during lifting and lowering. The connector 4412 is a square piece with a connecting groove in the middle, and the connector 4412 is connected to the tray frame 442 via a fixing rod. A hydraulic cylinder 443 is also provided on the side of the tray frame 442. The body of the hydraulic cylinder 443 is fixed on the second transparent isolation cover 45. The piston rod head of the hydraulic cylinder 443 is connected to the tray frame 442. The lifting and lowering of the tray frame 442 is achieved by the hydraulic cylinder 443. The second transparent isolation cover 45 is fixedly installed on the base for sealing the washing plate 43 in the working state. A sampling electromagnetic block 102 is fixedly installed on the lower surface of the tray frame 442. When the tray frame 442 falls, the sampling electromagnetic block 102 is energized to suck up the tissue holding device. When the power is cut off, the tissue holding device is disconnected and placed into the corresponding device. The sampling electromagnetic block 102 shown is an electromagnetic strip or electromagnetic ring.

[0058] like Figure 7-11 As shown, the tissue holding device is a mesh strainer or a fine mesh sieve structure. A stir bar 91 is fixedly installed at the bottom of this device, repelling the magnet 92 located on the base of the tissue washing device 4. Figure 12 As shown, the magnet 92 is fixedly mounted on the upper surface of the gear 94 inside the base cavity. The gear 94 is driven by a motor. When energized, the motor drives the gear 94, causing the magnet 92 fixedly mounted on the gear 94 to rotate. Utilizing the principle of like poles repelling and unlike poles attracting, the magnetic field drives the stir bar 91 mounted at the bottom of the tissue holding device to rotate, causing the tissue holding device to perform circumferential rotation to complete the cleaning or dehydration work. The top of the tissue holding device is made of a material with magnetic attraction (the magnetic field strength around the magnet of a multi-connected magnetic stirrer is approximately 5-12 Gauss).

[0059] like Figure 12 The structure shown is the power mechanism of the tissue cleaning device 4 of the device. The device is a multi-link magnetic stirrer 9. The first gear is driven by a motor (motor 93) mounted on the base. The first gear rotates clockwise, which drives the adjacent second gear to rotate counterclockwise and drives the magnet 92 on it to rotate counterclockwise. The adjacent second gear meshes with the first gear. The subsequent gears 94 mesh with the previous gear in turn to move in the opposite direction and drive the magnet 92 on it to perform a circular motion.

[0060] It should be understood that the specific embodiments described above are merely illustrative or explanatory of the principles of this utility model and do not constitute a limitation thereof. Therefore, any modifications, equivalent substitutions, improvements, etc., made without departing from the spirit and scope of this utility model should be included within its protection scope. Furthermore, the appended claims are intended to cover all variations and modifications falling within the scope and boundaries of the appended claims, or equivalent forms of such scope and boundaries.

Claims

1. An integrated device for tissue separation and cleaning, characterized in that, The device includes a control console (1), a tissue separation worktable (2), and a tissue cleaning device (4); The control console (1) includes a first control surface (11) for regulating the tissue separation operating table (2) and a second control surface (12) for controlling the tissue cleaning device (4) to perform cleaning and transfer. The control console (1) is electrically connected to the tissue separation operating table (2) and the tissue cleaning device (4). The tissue separation operating table (2) includes a separation platform (21) and a first transparent isolation cover (3). The first transparent isolation cover (3) is fixedly installed on the separation platform (21) with the separation platform (21) as the base to form an independent operating space. The top of the first transparent isolation cover (3) is equipped with an ultraviolet disinfection lamp, and the bottom of the side wall is provided with a window (31) to facilitate tissue separation. The temperature in the operating space is controlled by a semiconductor cooler set at the bottom of the separation platform (21). The base of the tissue cleaning device (4) is equipped with a multi-linked magnetic stirrer (9). The upper end of the base is provided with a tissue holding vessel (41), a low-temperature tissue storage box (42), an elution plate (43), and a support (44). The tissue holding vessel (41) is a tubular mesh strainer with a stir bar (91) at the bottom. The elution plate (43) is a horizontally movable elution plate (43) with a slide rail (20) at the bottom. The elution plate (43) is provided with a working groove (5) for elution. The low-temperature tissue storage box (42) is a cavity fixedly installed in the shell of the second control panel (12) at the same height as the elution plate (43). The support (44) includes a support column (441) and a tray (442). The tray (442) is installed above the elution plate (43) through the support column (441). The tissue is picked up and put in by the adsorption mesh strainer in the guide groove (4411) of the support column (441).

2. The integrated tissue separation and cleaning device according to claim 1, characterized in that, The separation platform (21) is also equipped with an electronic scale (22) for weighing tissue blocks, and the function buttons of the electronic scale (22) are located on the first control panel (11).

3. The integrated tissue separation and cleaning device according to claim 1, characterized in that, The window (31) is located at the bottom of the side wall facing the first control panel (11), and the window block is connected to the side wall of the transparent isolation cover by a snap fastener.

4. The integrated tissue separation and cleaning device according to claim 1, characterized in that, The washing plate (43) is provided with multiple sets of working tanks (5). Each set of working tanks (5) includes a row of washing tanks (51), a row of dehydration tanks (52) and a row of storage tanks (53). The washing tanks (51), dehydration tanks (52) and storage tanks (53) of each set of working tanks (5) are arranged alternately in the horizontal direction.

5. The integrated tissue separation and cleaning device according to claim 1, characterized in that, The top of the mesh is provided with a suction port that attracts the sampling electromagnetic block (102) when it is energized.

6. The integrated tissue separation and cleaning device according to claim 4, characterized in that, The washing tank (51) is equipped with a washing pipe (7), the dehydration tank (52) is equipped with a dehydration pipe (6), and the storage tank (53) is equipped with a covered EP pipe (8).

7. The integrated tissue separation and cleaning device according to claim 6, characterized in that, The dehydration tube (6) has a three-layer structure. Its outer layer is made of PVC material that can be sterilized by high pressure, the middle layer is a hollow structure, and the cavity is equipped with replaceable absorbent paper. The inner layer of the tube wall is made of absorbent fiber material that prevents tissue adhesion.

8. The integrated tissue separation and cleaning device according to claim 1, characterized in that, The plate frame (442) is raised and lowered by a cylinder, and an electromagnetic strip / block adapted to the working groove (5) is installed on the lower surface of the plate frame (442).

9. The integrated tissue separation and cleaning device according to claim 1, characterized in that, The top cover of the low-temperature tissue storage box (42) is provided with multiple round holes for placing EP tubes to temporarily store tissue blocks.

10. The integrated tissue separation and cleaning device according to claim 1, characterized in that, The bottom of the washing plate (43) is provided with a slide rail (20), and the washing plate (43) moves horizontally on the slide rail (20) by the pushing and pulling action of the telescopic rod (101) connected to its side wall.

Images