Flow cytometry kit convenient to store and transport

Abstract

The utility model discloses a flow cytometry kit convenient to store and transport, and relates to the field of biological kits. The kit comprises a kit main body, a placing plate is arranged above the inner side of the kit main body, a bearing mechanism is arranged on the placing plate, a bottom plate begins to move upwards and longitudinally through the bearing mechanism and screwing of an adjusting bolt, and the bottom plate is connected with a plurality of movable columns, so that the bottom plate can move upwards and longitudinally; meanwhile, due to the fact that the movable columns and the fixed columns are arranged on the containing plate in a staggered mode, when the movable columns ascend, the height difference between the movable columns and the fixed columns is gradually increased, and the movable columns are moved to the fixed columns; the flow cytometry reagent placed on the inner side of the movable column and the inner side of the fixed column can be distinguished and taken more easily through the height staggered structural form, a user can take the reagent on the inner side of the jacked movable column firstly and then take the reagent in the fixed column, and the purpose of taking the reagent in batches is achieved.

Description

Technical Field

[0001] This invention relates to the field of biological reagent kits, specifically a flow cytometry detection kit that is easy to store and transport. Background Technology

[0002] A reagent kit is a box that holds chemical reagents such as drug residues. It is used to hold chemical reagents for detecting chemical components, drug residues, virus types, etc., and is generally used by hospitals and pharmaceutical companies.

[0003] Existing reagent kits for flow cytometry often need to consider the ease of handling the reagents during use. The traditional solution is to arrange the reagents loosely, but this reduces the amount of reagents that can be transported, thus decreasing the ease of use of the kit. Utility Model Content

[0004] Based on this, the purpose of this utility model is to provide a flow cytometry detection kit that is easy to store and transport, so as to solve the technical problem that the number of reagents per unit area of ​​traditional kits conflicts with the convenience of subsequent reagent retrieval.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a flow cytometry detection kit that is easy to store and transport, comprising a kit body, a placement plate disposed on the upper inner side of the kit body, a supporting mechanism disposed on the placement plate, the supporting mechanism comprising a plurality of fixed posts disposed on the surface of the placement plate, and a through groove being formed between adjacent fixed posts, a limiting sleeve disposed below the through groove, a movable post being sleeved on the inner side of the limiting sleeve, a base plate disposed at the bottom of the movable post, a plurality of through holes being formed on the surface of the base plate, an adjusting bolt being threadedly connected to the base plate, and empty grooves being formed on the inner sides of the fixed posts and the movable posts for placing reagent tubes.

[0006] By adopting the above technical solution, the rotating adjusting bolt is tightly connected to the base plate by the thread at its lower end. As the adjusting bolt is gradually tightened, the base plate is subjected to an upward force and begins to move along the longitudinal direction. Since the base plate is the supporting foundation of the movable column, this movement also drives the movable column to rise synchronously. At the same time, the movable column and the fixed column are arranged in an alternating manner on the placement plate.

[0007] Furthermore, the adjusting bolt is rotatably connected to the placement plate via a thrust bearing, and a handwheel is provided on the top of the adjusting bolt to provide the user with the point of force application for the adjusting bolt.

[0008] By adopting the above technical solutions, it is ensured that the adjusting bolt can rotate smoothly without obstruction, while avoiding wear caused by direct friction, which greatly extends the service life. The use of thrust bearings makes the rotation of the adjusting bolt more flexible, providing stable support for the subsequent movement of the base plate and movable column.

[0009] Furthermore, the limiting sleeve is used to restrict the position of the movable column, and the movable column engages and slides inside the limiting sleeve.

[0010] By adopting the above technical solution, the limiting sleeve serves as a fixed reference point during the process of the movable column rising or falling with the base plate, ensuring that the movable column can only move within a predetermined range. This avoids the movable column from shifting or becoming uncontrollable during movement, thereby ensuring the stability of the internal structure of the reagent kit and the safety of the reagents.

[0011] By adopting the above technical solution, the reagent tubes can be securely placed in the empty slot, avoiding damage to the reagent tubes or leakage of reagents due to bumps or collisions during transportation or operation. The presence of the empty slot effectively protects the reagent tubes and the reagents inside, ensuring the integrity and safety of the reagents.

[0012] Furthermore, the through hole is used to provide a through hole for the fixing column to penetrate the base plate, and a top cover is rotatably provided on one side of the top of the reagent kit body, and a handle is rotatably provided on the top of the top cover.

[0013] By adopting the above technical solution, the presence of through holes also allows for easy disassembly or adjustment of the movable column when needed, improving the flexibility and maintainability of the reagent kit.

[0014] Furthermore, a partition is fixedly installed on the lower inner side of the reagent kit body, and a cavity is formed between the lower part of the partition and the inner side of the reagent kit body for holding ice water.

[0015] By adopting the above technical solution, not only is the internal space of the reagent kit more rationally utilized, but a stable supporting platform is also provided for the cavity below. The cavity is specifically designed to hold ice water, which allows ice water to be easily added to maintain the appropriate storage temperature of the reagent kit when a low-temperature environment needs to be maintained, thereby ensuring the activity and stability of the reagent.

[0016] Furthermore, a water inlet is provided on one side of the surface of the placement plate, and a water outlet is provided on one side of the reagent kit body. The water inlet is connected to the interior of the cavity through a connecting pipe.

[0017] By adopting the above technical solution, the water inlet design allows users to easily inject ice water into the cavity. The direct connection between the water inlet and the connecting pipe ensures smooth and unobstructed water flow, reducing inconvenience and the risk of leakage during operation. This allows the reagent kit to be quickly and effectively cooled when needed, thus meeting the reagent's requirements for a low-temperature environment.

[0018] In summary, the present invention has the following main advantages:

[0019] 1. This utility model uses a support mechanism to adjust the bolts. The bolts are connected to the base plate via a threaded connection. As the adjusting bolts rotate, the base plate begins to move longitudinally upward. Since the base plate is connected to multiple movable columns, this movement simultaneously causes the position of the movable columns to change. At the same time, since the movable columns and fixed columns are arranged in an alternating pattern on the placement plate, the height difference between the movable columns and the fixed columns gradually increases as the movable columns rise. This staggered height structure makes it easier to distinguish and retrieve the flow cytometry reagents placed inside the movable and fixed columns. Users can first retrieve the reagents inside the lifted movable columns and then retrieve the reagents in the fixed columns, achieving the purpose of batch retrieval. This not only increases the number of flow cytometry reagents placed per unit area and improves the convenience and efficiency of transportation, but also takes into account the convenience of subsequent reagent retrieval.

[0020] 2. This utility model, by setting up an inlet, an outlet, and a cavity, allows users to easily inject ice water simply by pouring it in through the inlet. This process is simple and quick, requiring no complicated operating steps, greatly improving user efficiency. At the same time, the connecting pipe acts as a bridge between the inlet and the cavity, ensuring smooth flow of ice water. The connecting pipe allows ice water to enter the cavity without obstruction, avoiding problems caused by pipe blockage or poor water flow. In this way, the cavity can be quickly filled with ice water, providing a stable low-temperature environment for flow cytometry reagents and ensuring the activity and stability of the reagents during transportation. Attached Figure Description

[0021] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0022] Figure 2 This is a cross-sectional structural diagram of the present invention;

[0023] Figure 3 This is a three-dimensional structural diagram of the movable column of this utility model;

[0024] Figure 4 This is an exploded structural diagram showing the arrangement of the fixed and movable columns of this utility model;

[0025] Figure 5 This is a cross-sectional structural diagram of the main view of this utility model.

[0026] In the diagram: 1. Main body of the reagent kit; 2. Top cover; 3. Handle; 4. Placement plate; 5. Supporting mechanism; 501. Fixing column; 502. Through groove; 503. Movable column; 504. Limiting sleeve; 505. Base plate; 506. Adjusting bolt; 507. Through hole; 6. Partition plate; 7. Cavity; 801. Water inlet; 802. Water outlet; 803. Through tube. Detailed Implementation

[0027] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.

[0028] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. In addition, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0029] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation", "connection", "linking", and "setting" should be interpreted broadly. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections or electrical connections; they can refer to direct connections or indirect connections through an intermediate medium; and they can refer to the internal connection of two components. For those skilled in the art, the specific meaning of the above terms in this utility model can be understood according to the specific circumstances.

[0030] The embodiments of this utility model will be described below based on its overall structure.

[0031] Example 1:

[0032] A flow cytometry assay kit that is easy to store and transport, such as Figures 1-5As shown, the kit includes a main body 1, a placement plate 4 is provided on the upper inner side of the main body 1, and a supporting mechanism 5 is provided on the placement plate 4. The supporting mechanism 5 includes multiple fixed posts 501. A through groove 502 is formed on the surface of the placement plate 4 and between adjacent fixed posts 501. A limiting sleeve 504 is provided below the through groove 502. A movable post 503 is sleeved on the inner side of the limiting sleeve 504. A base plate 505 is provided at the bottom of the movable post 503. Multiple through holes 507 are formed on the surface of the base plate 505. An adjusting bolt 506 is threadedly connected to the base plate 505. By rotating the adjusting bolt 506, the bolt is tightened with the base plate 505 by the thread at its lower end. Closely connected, as the adjusting bolts 506 are gradually tightened, the base plate 505 is subjected to an upward force and begins to move along the longitudinal direction. Since the base plate 505 is the supporting foundation for the movable column 503, this movement also causes the movable column 503 to rise synchronously. At the same time, since the movable column 503 and the fixed column 501 are arranged in an alternating manner on the placement plate 4, a significant height difference is formed between them and the fixed column 501 when the movable column 503 rises. This staggered layout allows users to easily distinguish the flow cytometry reagents inside the movable column 503 and the fixed column 501, and to take them out in batches as needed.

[0033] See Figure 2 , Figure 3 The adjusting bolt 506 is rotatably connected to the placement plate 4 via a thrust bearing. A handwheel is provided on the top of the adjusting bolt 506 to provide the user with a point of force application for the adjusting bolt 506, ensuring smooth and unobstructed rotation of the adjusting bolt 506 and avoiding wear caused by direct friction, thus greatly extending its service life. The use of a thrust bearing makes the rotation of the adjusting bolt 506 more flexible, providing stable support for the subsequent movement of the base plate 505 and the movable column 503. At the same time, a handwheel is specially provided on the top of the adjusting bolt 506. This handwheel not only provides the user with a clear point of force application, making it easier and less strenuous to rotate the adjusting bolt 506, but also improves the convenience of operation.

[0034] See Figure 4The limiting sleeve 504 is used to restrict the position of the movable column 503, and the movable column 503 engages and slides inside the limiting sleeve 504. During the process of the movable column 503 rising or falling with the base plate 505, the limiting sleeve 504 serves as a fixed reference point, ensuring that the movable column 503 can only move within a predetermined range, avoiding deviation or loss of control during movement, thereby ensuring the stability of the internal structure of the reagent kit and the safety of the reagent. At the same time, the movable column 503 engages and slides inside the limiting sleeve 504. This sliding method not only makes the movement of the movable column 503 smoother, but also reduces the friction and wear that may occur during movement, and ensures that the movable column 503 can maintain a stable posture during movement, and will not tilt or collapse due to external force or vibration.

[0035] See Figure 3 , Figure 4 The through hole 507 is used to provide a through hole for the fixed column 501 to pass through the base plate 505. The top cover 2 is rotatably provided on one side of the top of the reagent kit body 1, and the top of the top cover 2 is rotatably provided with a handle 3. The presence of the through hole 507 also makes it easy to disassemble or adjust the movable column 503 when needed, which improves the flexibility and maintainability of the reagent kit. At the same time, the top cover 2 is rotatably provided on one side of the top of the reagent kit body 1, which not only protects the reagents and components inside the reagent kit from interference and contamination from the external environment, but also makes it convenient for users to quickly open and close the reagent kit during use.

[0036] See Figure 5 A partition 6 is fixedly installed on the lower inner side of the reagent kit body 1. A cavity 7 is formed between the lower part of the partition 6 and the inner side of the reagent kit body 1 for holding ice water. This not only makes more rational use of the internal space of the reagent kit, but also provides a stable support platform for the cavity 7 below. The cavity 7 is specifically designed to hold ice water, so that when the reagent kit needs to maintain a low temperature environment, ice water can be easily added to maintain the appropriate storage temperature of the reagent, thereby ensuring the activity and stability of the reagent. At the same time, the combination of the cavity 7 and the partition 6 also improves the heat preservation performance of the reagent kit. Since the cavity 7 is located at the bottom of the reagent kit and is surrounded by the partition 6 and the inner side of the reagent kit body 1, a relatively closed heat preservation space is formed.

[0037] Example 2:

[0038] See Figure 1 , Figure 2A water inlet 801 is provided on one side of the surface of the placement plate 4, and a water outlet 802 is provided on one side of the reagent kit body 1. The water inlet 801 is connected to the inside of the cavity 7 through a connecting tube 803. The design of the water inlet 801 allows the user to easily inject ice water into the cavity 7. The direct connection between the water inlet 801 and the connecting tube 803 ensures smooth and unobstructed water flow, reducing inconvenience and leakage risks during operation. This allows the reagent kit to quickly and effectively add ice water when cooling is required to meet the reagent's low-temperature environment requirements. At the same time, the design of the water outlet 802 facilitates the user to drain the water from the cavity 7. When the reagent kit no longer needs to maintain a low-temperature environment or when the ice water needs to be replaced, the user can easily drain the water through the water outlet 802, avoiding contamination or corrosion caused by water retention inside the reagent kit.

[0039] The implementation principle of this utility model is as follows: When it is necessary to transport flow cytometry reagents through the reagent kit, firstly, each flow cytometry reagent is placed in the groove formed inside the fixed column 501 and the movable column 503. Then, external ice water is injected into the cavity 7 through the water inlet 801 and the through pipe 803 to meet the temperature requirements in the subsequent flow cytometry reagent transportation process. After that, the top cover 2 is placed on the top of the reagent kit body 1, and then the reagent kit is transported.

[0040] When it is necessary to remove the flow cytometry reagents inside the kit, first open the top cover 2, then turn the adjusting bolt 506. The adjusting bolt 506 is threadedly connected to the base plate 505, causing the base plate 505 to move upwards longitudinally. Simultaneously, this moves multiple movable columns 503. Because the movable columns 503 and the fixed columns 501 are arranged in an alternating pattern, the flow cytometry reagents placed inside the movable columns 503 and fixed columns 501 can be gradually arranged in a highly staggered structure. The flow cytometry reagents inside the raised movable columns 503 can be removed first, followed by the flow cytometry reagents in the fixed columns 501. This allows for batch removal. In this invention, the number of flow cytometry reagents that can be placed per unit area can be increased, improving the convenience and efficiency of flow cytometry reagent transportation, while also ensuring the ease of subsequent removal of the flow cytometry reagents, thereby improving the ease of use and practicality of the kit.

[0041] All parts not covered in this utility model are the same as or can be implemented using existing technologies, and will not be described in detail here.

[0042] Although embodiments of the present invention have been shown and described, these specific embodiments are merely explanations of the present invention and are not intended to limit the invention. The specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. After reading this specification, those skilled in the art may make modifications, substitutions, and variations to the embodiments as needed without departing from the principles and spirit of the present invention, provided that such modifications, substitutions, and variations are within the scope of the claims of the present invention and are protected by patent law.

Claims

1. A flow cytometry assay kit that is easy to store and transport, characterized in that: The kit includes a main body, a placement plate on the upper inner side of the main body, a supporting mechanism on the placement plate, a plurality of fixed posts on the surface of the placement plate, and a through groove between adjacent fixed posts. A limiting sleeve is provided below the through groove, a movable post is sleeved on the inner side of the limiting sleeve, a base plate is provided at the bottom of the movable post, a plurality of through holes are provided on the surface of the base plate, and an adjusting bolt is threaded onto the base plate. Hollow grooves are provided on the inner sides of the fixed posts and the movable posts for placing reagent tubes.

2. The flow cytometry assay kit according to claim 1, characterized in that: The adjusting bolt is rotatably connected to the placement plate via a thrust bearing, and a handwheel is provided on the top of the adjusting bolt to provide the user with the point of force application for the adjusting bolt.

3. The flow cytometry assay kit according to claim 1, characterized in that: The limiting sleeve is used to restrict the position of the movable column, and the movable column engages and slides inside the limiting sleeve.

4. The flow cytometry assay kit according to claim 1, characterized in that: The through hole is used to provide a through hole for the fixing column to pass through the base plate. A top cover is rotatably provided on one side of the top of the reagent kit body, and a handle is rotatably provided on the top of the top cover.

5. The flow cytometry assay kit according to claim 1, characterized in that: A partition is fixedly installed on the lower inner side of the reagent kit body, and a cavity is formed between the lower part of the partition and the inner side of the reagent kit body for holding ice water.

6. The flow cytometry assay kit according to claim 1, characterized in that: A water inlet is provided on one side of the surface of the placement plate, and a water outlet is provided on one side of the main body of the reagent kit. The water inlet is connected to the interior of the cavity through a connecting pipe.

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