Cryopreservation device

Abstract

The embodiment of the utility model relates to the technical field of low-temperature storage equipment, in particular to a cryopreservation device. According to the cryopreservation device provided by the embodiment of the invention, the storage part is arranged in the storage cavity to store the sample. Wherein the storage part comprises a plurality of storage mechanisms, the number of the storage mechanisms is increased, and the storage capacity of the cryopreservation device is improved; the storage mechanism is annular and sequentially sleeved inside and outside in the radial direction, and the structural compactness of the storage component is improved. And a transfer part is arranged on the inner side of the storage mechanism on the innermost ring, so that the sample box is transferred. The transfer part is configured to ascend and descend in the vertical direction and move in the first direction, and the driving mechanism drives the storage mechanism to rotate, so that the transfer part can output the sample boxes at any height on the storage mechanism or store the sample boxes at any height of the storage mechanism.

Description

TECHNICAL FIELD

[0001] Embodiments of the present application relate to the technical field of low-temperature storage devices, and in particular to a cryopreservation device. BACKGROUND

[0002] In order to keep biological tissues such as stem cells, blood, immune cells, etc. active for a long time, the samples are usually stored in sample tubes, and the sample box containing multiple sample tubes is stored in a cryopreservation device.

[0003] In the related art, the storage capacity of the cryopreservation device is small, and increasing the storage capacity of the cryopreservation device will inevitably increase the volume of the cryopreservation device, thereby increasing the occupied space of the cryopreservation device, and increasing the storage capacity of the cryopreservation device will make its structure more complex and increase the difficulty of taking and placing.

[0004] Therefore, there is a need for a new technical solution to solve the above technical problems. Practical new type content

[0005] Embodiments of the present application provide a cryopreservation device to improve storage capacity and reduce the difficulty of taking and placing.

[0006] In a first aspect, the embodiments of the present application provide a cryopreservation device, which comprises:

[0007] A box assembly is configured to:

[0008] A storage cavity is configured to store a sample box.

[0009] A storage component is installed in the storage cavity and configured to accommodate the sample box; the storage component comprises:

[0010] A plurality of storage mechanisms are configured to accommodate the sample box; the storage mechanisms are annular; the plurality of storage mechanisms are coaxially arranged, and the plurality of storage mechanisms are sequentially arranged inside and outside along the radial direction.

[0011] A driving mechanism is configured to drive each storage mechanism to rotate independently.

[0012] A transfer component is arranged inside the innermost circle of the storage mechanisms; the transfer component is configured to vertically ascend and descend and move along the first direction to transfer the sample box; wherein the vertical direction is perpendicular to the first direction.

[0013] The cryopreservation device provided by the embodiments of the present application stores samples by arranging a storage component in the storage cavity. The storage component includes a plurality of storage mechanisms, and the number of storage mechanisms is increased to improve the storage capacity of the cryopreservation device. The storage mechanisms are arranged in a ring shape and are sequentially arranged in the radial direction to improve the compactness of the storage component. A transfer component is arranged inside the innermost storage mechanism to transfer the sample box. The transfer component is configured to move along the vertical direction and move along the first direction. The driving mechanism drives the rotation of the storage mechanism, so that the transfer component can output the sample box at any height on the storage mechanism or store the sample box at any height on the storage mechanism.

[0014] In some embodiments of the present application, the driving mechanism drives the independent rotation of each storage mechanism to adjust the moving direction of the target position towards the transfer component. Then, the transfer component is configured to move along the vertical direction to make the transfer component opposite to the target position of the storage mechanism. The transfer component is also configured to move along the first direction to transport the sample box to the target position on the storage mechanism or take out the sample box at the target position. The transfer component is located inside the ring-shaped storage mechanism, and its position in the horizontal plane does not change. Through the rotation of the storage mechanism, the sample box is moved to the position corresponding to the transfer component. Then, the position of the sample box is determined by the lifting of the transfer component. Only the movement of the transfer component along the first direction is required to realize the taking and placing of the sample box, and the difficulty of taking and placing is low.

[0015] In some embodiments of the present application, the transfer component includes:

[0016] The fixed part is arranged inside the innermost storage mechanism.

[0017] The translation mechanism includes:

[0018] The first moving assembly is configured to move the sample box along the first direction. The first moving assembly is arranged on the fixed part.

[0019] The second moving assembly is connected to the first moving assembly and is configured to move the sample box along the first direction. The second moving assembly is provided with a shovel disc to accommodate the sample box.

[0020] The translation driving assembly is connected to the first moving assembly. The translation driving assembly is configured to drive the first moving assembly to move along the first direction, so that the first moving assembly drives the second moving assembly to move along the first direction.

[0021] In some embodiments of the present application, the translation mechanism is provided with a translation driving assembly, which drives the first and second moving assemblies to move in the first direction, so as to convey the sample box in the first direction. In addition, the translation mechanism of the embodiments of the present application is provided with two moving assemblies, so that the translation mechanism has two levels of movement, increases the moving distance of the translation mechanism in the first direction, and increases the storage capacity of the cryopreservation device even if a multi-turn storage mechanism is provided. The translation mechanism can transfer the sample box in the storage cavity to the buffer cavity.

[0022] In some embodiments of the present application, the first moving assembly comprises:

[0023] A first transmission wheel set is rotatably installed on the fixed member, and the first transmission wheel set is connected with the translation driving assembly;

[0024] A first flexible transmission member is arranged around the first transmission wheel set, and at least a part of the first flexible transmission member extends in the first direction;

[0025] The second moving assembly is connected with the part of the first flexible transmission member extending in the first direction.

[0026] In some embodiments of the present application, the first moving assembly is provided with a first transmission wheel set connected with the translation driving assembly, and at least a part of the first flexible transmission member extends in the first direction. Under the driving of the translation driving assembly, at least a part of the first flexible member moves in the first direction. The second moving assembly is connected with the part of the first flexible transmission member extending in the first direction. The translation driving assembly drives at least a part of the first flexible transmission member to move in the first direction through the first transmission wheel set, so as to drive the second moving assembly to move in the first direction, and realize the first level of movement of the translation mechanism.

[0027] In some embodiments of the present application, the second moving assembly comprises:

[0028] A moving table is slidably installed on the fixed member, and the moving table is connected with the part of the first flexible transmission member extending in the first direction;

[0029] A second transmission wheel set is rotatably installed on the moving table;

[0030] A second flexible transmission member is arranged around the second transmission wheel set, and at least a part of the second flexible transmission member extends in the first direction;

[0031] The part of the second flexible transmission member extending in the first direction is connected with the fixed member and the shovel disc, respectively.

[0032] In some embodiments of the present application, the first mobile assembly is connected with the mobile platform through the first flexible transmission member, so that the first mobile assembly can drive the second mobile assembly to move; the second transmission wheel set and the second flexible transmission member are arranged, so that at least part of the second flexible transmission member extends in the first direction; the part of the second flexible transmission member extending in the first direction is connected with the fixing member, and the second flexible transmission member is limited, so that the second flexible transmission member moves in the first direction relative to the mobile platform under the driving of the first mobile assembly; the part of the second flexible transmission member extending in the first direction is connected with the shovel disc, so that the shovel disc moves in the first direction relative to the mobile platform, and the second-level movement of the translation mechanism is realized.

[0033] Moreover, the translation mechanism of the embodiments of the present application realizes two-level movement through one translation driving assembly, the first mobile assembly and the second mobile assembly, has a large movement stroke, and has a simple structure.

[0034] In some embodiments of the present application, the translation mechanism further comprises a first connecting member connecting the first flexible transmission member and the mobile platform.

[0035] In some embodiments of the present application, the first flexible transmission member and the mobile platform are connected through the first connecting member, so that when the first flexible transmission member moves in the first direction, the mobile platform is driven to move in the first direction through the first connecting member.

[0036] In some embodiments of the present application, the translation mechanism further comprises a second connecting member fixed on the fixing member and connected with the second flexible transmission member.

[0037] In some embodiments of the present application, the second connecting member is fixed on the fixing member and connected with the second flexible transmission member. The second flexible transmission member is limited, so that the second flexible transmission member moves relative to the mobile platform, and the second-level movement of the translation mechanism is realized.

[0038] In some embodiments of the present application, the translation mechanism further comprises a third connecting member connecting the shovel disc and the second flexible transmission member.

[0039] In some embodiments of the present application, the third connecting member is arranged to connect the shovel disc and the second flexible transmission member. In this way, when the second flexible transmission member moves in the first direction relative to the mobile platform, the shovel disc is driven to move in the first direction relative to the mobile platform through the third connecting member, and the second-level movement of the translation mechanism is realized.

[0040] In some embodiments of the present application, a first guide rail is arranged on the fixing member, and the first guide rail extends in the first direction.

[0041] The bottom of the moving table is provided with a first pulley, which is slidable relative to the first guide rail.

[0042] Some embodiments of the present application can guide the movement of the moving table along the first direction through the cooperation of the first pulley and the first guide rail. Moreover, the contact area between the first pulley and the first guide rail is small, which can reduce the friction therebetween, so that the movement of the moving table relative to the fixed part is smoother.

[0043] In some embodiments of the present application, the top of the moving table is provided with a second guide rail extending along the first direction.

[0044] The second pulley is provided on the shovel disc and is slidable relative to the second guide rail.

[0045] Some embodiments of the present application can guide the movement of the shovel disc along the first direction through the cooperation of the second pulley and the second guide rail. Moreover, the contact area between the second pulley and the second guide rail is small, which can reduce the friction therebetween, so that the movement of the shovel disc relative to the moving table is smoother.

[0046] In some embodiments of the present application, the diameter of the second pulley is smaller than that of the first pulley.

[0047] The diameter of the second pulley is small, which can reduce the mass of the second moving assembly and save the driving force for driving the second moving assembly to move. The diameter of the first pulley is large, which can increase the carrying capacity of the moving table. In particular, when the shovel disc is extended relative to the moving table, the large first pulley can provide greater limiting force, which can reduce the possibility of the shovel disc sagging and help to ensure the reliability and stability of the movement of the sample box driven by the shovel disc.

[0048] In some embodiments of the present application, the first transmission wheel set includes a driving wheel located above the fixed part.

[0049] The translation driving assembly includes:

[0050] A translation transmission shaft extending in the vertical direction, and the translation transmission shaft is arranged in the shaft hole, so that the driving wheel can slide along the translation transmission shaft.

[0051] A translation driver mounted on the outside of the storage cavity, the translation driver is connected with the translation transmission shaft, and the translation driver is configured to drive the driving wheel to rotate through the translation transmission shaft.

[0052] In some embodiments of the present application, the translation driving assembly is arranged outside the storage cavity, so that the translation driver is located outside the low-temperature environment of the storage cavity, which is conducive to ensuring the service life of the translation driver, and the low-temperature resistant driver does not need to be selected, which is conducive to reducing the cost of the transfer component. The driving force outside the storage cavity is transmitted to the driving wheel through the translation transmission shaft, and the translation transmission shaft and the shaft hole of the driving wheel are matched, so that the translation transmission shaft drives the driving wheel to rotate, and the driving wheel can also move along the translation transmission shaft, so that the matching of the translation transmission shaft and the driving wheel does not affect the vertical movement of the fixing part.

[0053] In some embodiments of the present application, the transfer component comprises a lifting mechanism, and the lifting mechanism comprises:

[0054] A lifting transmission assembly is connected with the fixing part.

[0055] A lifting driver is installed outside the storage cavity, the lifting driver is connected with the lifting transmission assembly, and the lifting driver drives the fixing part to move vertically through the lifting transmission assembly.

[0056] In some embodiments of the present application, the transfer component comprises a lifting mechanism to drive the sample plate box to move vertically. The lifting mechanism provides lifting driving force for the fixing part through the lifting driver, and the lifting driver is located outside the storage cavity, so that the lifting driver is located outside the low-temperature environment of the storage cavity, which is conducive to ensuring the service life of the lifting driver, and the low-temperature resistant driver does not need to be selected, which is conducive to reducing the cost of the transfer component. And the lifting transmission assembly is arranged to transmit the driving force outside the storage cavity to the inside of the storage cavity.

[0057] In some embodiments of the present application, the lifting transmission assembly comprises:

[0058] A lead screw extends vertically, and the lead screw is connected with the lifting driver.

[0059] A nut is formed on the fixing part, and the nut is threadedly connected with the lead screw.

[0060] Therefore, the lifting transmission assembly of some embodiments of the present application converts the rotation of the lifting driver into the linear movement of the fixing part along the vertical direction through the lead screw and the nut, transmits the driving force outside the storage cavity to the inside of the storage cavity, and also makes the structure of the lifting mechanism compact.

[0061] In some embodiments of the present application, the storage mechanism comprises:

[0062] An upper turntable component is annular.

[0063] A lower turntable component is annular, and the lower turntable component is arranged below the upper turntable component vertically and at intervals.

[0064] a plurality of storage shelves, the storage shelves being fixed between the upper turntable member and the lower turntable member, and the plurality of storage shelves being arranged along a circumference of the upper turntable member.

[0065] In some embodiments of the present application, the storage mechanism increases the storage capacity of the cryopreservation device by arranging a plurality of storage shelves between the upper turntable member and the lower turntable member, and increasing the number of storage shelves. The upper turntable member and the lower turntable member are arranged to provide a fixed position for the storage shelves.

[0066] In some embodiments of the present application, the storage component further comprises a support disc.

[0067] The support disc is fixed in the storage cavity, and the support disc is located below the lower turntable member.

[0068] The support disc is provided with a roller member, and the roller member is configured to support the lower turntable member and limit the rotation of the lower turntable member around the center thereof.

[0069] In some embodiments of the present application, the support disc is arranged, and the roller member is arranged on the support disc to limit the rotation direction of the lower turntable member and provide support for the lower turntable member. In addition, the rotation resistance of the lower turntable member can be reduced, so that the storage mechanism can rotate smoothly.

[0070] In some embodiments of the present application, a plurality of driving mechanisms are arranged, and each driving mechanism is connected with one of the storage mechanisms to drive the rotation of the storage mechanism.

[0071] In some embodiments of the present application, a plurality of driving mechanisms are arranged to drive the rotation of one storage mechanism, so that the structure of each driving mechanism is relatively simple, and the rotation efficiency of the storage mechanism and the transfer rate of the sample box can be improved.

[0072] In some embodiments of the present application, the driving mechanism comprises:

[0073] a rotation driver mounted on the outside of the storage cavity, and the rotation driver being configured to drive the rotation of the storage mechanism;

[0074] a rotation transmission assembly connected with the output end of the rotation driver and the storage mechanism, respectively, to transmit the driving force of the rotation driver to the storage mechanism.

[0075] In some embodiments of the present application, the driving mechanism provides a rotating driving force for the rotation of the storage mechanism by arranging a rotating driver. The rotating driver is installed outside the storage cavity, so that the rotating driver is located outside the low-temperature environment of the storage cavity, which is conducive to ensuring the service life of the rotating driver, and does not need to select a low-temperature resistant driver, which is conducive to reducing the cost of the driving mechanism. The driving force outside the storage cavity is transmitted to the inside of the storage cavity through the rotating transmission assembly, and the rotation of the storage mechanism is realized.

[0076] In a second aspect, the embodiments of the present application provide a cryopreservation device, which comprises:

[0077] The box assembly is configured to:

[0078] The storage cavity is configured to store sample boxes.

[0079] The buffer cavity is configured to be selectively in communication with the buffer cavity. The temperature of the buffer cavity is lower than that of the storage cavity. The buffer cavity and the storage cavity are arranged side by side along a first direction.

[0080] The storage component is installed in the storage cavity and is configured to accommodate the sample boxes. The storage component comprises:

[0081] The first storage mechanism is annular. The first storage mechanism is configured to store the sample boxes.

[0082] The second storage mechanism is annular. The first storage mechanism is configured to store the sample boxes. The second storage mechanism is arranged coaxially with the first storage mechanism.

[0083] The driving mechanism is configured to drive the first storage mechanism and the second storage mechanism to rotate independently.

[0084] The transfer component is arranged inside the first storage mechanism. The transfer component is configured to vertically ascend and descend and move along the first direction, so as to transfer the sample boxes between the buffer cavity and the storage mechanism.

[0085] The cryopreservation device of the embodiments of the present application stores samples by arranging a storage component in the storage cavity. The storage component comprises a first storage mechanism and a second storage mechanism, which increases the number of storage mechanisms and improves the storage capacity of the cryopreservation device. The storage mechanisms are annular, and the second storage mechanism is arranged outside the first storage mechanism, which improves the compactness of the storage component. A transfer component is arranged inside the first storage mechanism to transfer the sample boxes. The transfer component is configured to vertically ascend and descend and move along the first direction. The driving mechanism drives the storage mechanisms to rotate, so that the transfer component can output the sample boxes at any height of the storage mechanisms or store the sample boxes at any height of the storage mechanisms.

[0086] And, the moving direction of the transfer component is same as the arrangement direction of the buffer cavity and the storage cavity, which ensures the transfer component to realize the transfer of the sample box between the buffer cavity and the storage cavity. BRIEF DESCRIPTION OF DRAWINGS

[0087] In order to more clearly illustrate the embodiments of the present application or the implementation manners in the related art, the drawings needed to be used in the embodiments or the related art description will be briefly introduced. Obviously, the drawings in the following description are some embodiments of the present application, and other drawings can also be obtained by those skilled in the art according to these drawings.

[0088] Figure 1 The structural schematic diagram of the cryopreservation device provided by some embodiments of the present application is shown in the figure.

[0089] Figure 2 The internal structural schematic diagram of the cryopreservation device provided by some embodiments of the present application is shown in the figure.

[0090] Figure 3 The internal structural schematic diagram of the cryopreservation device provided by some embodiments of the present application is shown in the figure.

[0091] Figure 4 The position schematic diagram of the internal structure of the buffer cavity and the position of the sample taking and placing mechanism provided by some embodiments of the present application is shown in the figure.

[0092] Figure 5 The structural schematic diagram of the cryopreservation device provided by some embodiments of the present application is shown in the figure.

[0093] Figure 6 The structural schematic diagram of the cryopreservation device provided by some embodiments of the present application is shown in the figure.

[0094] Figure 7 The structural schematic diagram of the storage mechanism provided by some embodiments of the present application is shown in the figure.

[0095] Figure 8 The partial structural schematic diagram below the lower turntable component provided by some embodiments of the present application is shown in the figure.

[0096] Figure 9 The partial structural schematic diagram below the lower turntable component provided by some embodiments of the present application is shown in the figure.

[0097] Figure 10 The partial structural schematic diagram of the lifting mechanism provided by some embodiments of the present application is shown in the figure.

[0098] Figure 11 The structural schematic diagram of the translation mechanism provided by some embodiments of the present application is shown in the figure.

[0099] Figure 12An exploded view of the translation mechanism provided for some embodiments of the present application;

[0100] Figure 13 A structural schematic view of the translation mechanism provided for some embodiments of the present application.

[0101] Legend of reference signs:

[0102] 10: sample box; 20: storage component; 30: sample taking and placing mechanism; 40: tube picking mechanism; 50: scanning mechanism; 60: transfer table; 70: transfer component; 71: fixing member; 711: guide hole; 712: first guide rail;

[0103] 100: box assembly; 101: storage cavity; 102: buffer cavity; 103: first taking and placing opening; 104: second taking and placing opening; 110: first box; 111: first tank; 120: second box; 121: second tank; 122: display component; 130: first heat preservation door; 140: second heat preservation door;

[0104] 200: storage mechanism; 210: upper turntable component; 220: lower turntable component; 230: storage rack; 240: support disc; 250: roller component; 251: load roller; 252: first guide roller; 260: intermediate turntable component; 270: connecting rod; 281: second guide roller; 282: third guide roller;

[0105] 300: driving mechanism; 310: rotary driver; 321: first gear; 322: first transmission shaft; 323: first transmission wheel; 324: first transmission belt; 330: gear ring;

[0106] 400: translation mechanism; 410: first moving assembly; 411: first transmission wheel set; 4111: driving wheel; 4112: shaft hole; 4113: driven wheel; 4114: limiting wheel; 412: first flexible transmission member;

[0107] 420: second moving assembly; 421: moving table; 4211: first pulley; 4212: second guide rail; 4213: main body part; 4214: connecting arm; 4215: end arm; 422: second transmission wheel set; 4221: third transmission wheel; 423: second flexible transmission member;

[0108] 430: translation driving assembly; 431: translation driver; 432: translation transmission shaft; 433: third transmission shaft;

[0109] 440: shovel disc; 441: second pulley; 450: first connecting member; 460: second connecting member; 470: third connecting member;

[0110] 500: lifting mechanism; 510: lifting transmission assembly; 511: screw rod; 512: nut; 520: lifting driver; 530: guide rod; 540: second transmission shaft. DETAILED DESCRIPTION

[0111] For the purpose of clarity, the present application will be described in detail with reference to the attached drawings, which are presented for the purpose of illustration and are not intended to limit the application. Obviously, the examples described hereinbelow are only a part of the embodiments of the present application, but not all of them.

[0112] It should be noted that the brief description of the terms in the present application is only for the convenience of understanding the embodiments described next, and is not intended to limit the embodiments of the present application. Unless otherwise specified, these terms should be understood according to their ordinary and general meanings.

[0113] In addition, the terms "comprise" and "have" and any variations thereof are intended to cover but not exclusively include, for example, a product or device that contains a series of components does not have to be limited to those components clearly listed, but can include other components that are not clearly listed or inherent to these products or devices.

[0114] In the description of the present application, it should be understood that the terms "center", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer" and the like indicate the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the present application.

[0115] The terms "first", "second" are only for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the technical features indicated. Therefore, the features defined with "first", "second" can explicitly or implicitly include one or more of the features. In the description of the present application, unless otherwise specified, the meaning of "a plurality of" is two or more.

[0116] In the description of the present application, it should be noted that unless otherwise specified and limited, the terms "mounting", "connection", "connection" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium, or it can be the communication between the two elements inside. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0117] In the related art, the storage capacity of the cryopreservation device is small, and increasing the storage capacity of the cryopreservation device will inevitably increase the volume of the cryopreservation device, thereby increasing the space occupied by the cryopreservation device, and increasing the storage capacity of the cryopreservation device will make the structure more complex and increase the difficulty of taking and placing.

[0118] For the ring-shaped storage mechanism, from the edge of the storage mechanism towards the center, the storage space of the storage mechanism becomes smaller and smaller, and in order to adapt to the size of the sample box, the central region of the storage mechanism is not effectively utilized, resulting in waste of space.

[0119] Therefore, the embodiments of the present application provide a cryopreservation device, the storage component of which comprises a plurality of ring-shaped storage mechanisms, the plurality of storage mechanisms are coaxially arranged and sequentially sleeved in the radial direction, thereby increasing the storage capacity while making the structure of the storage component compact.

[0120] For the ring-shaped storage mechanism, from the edge of the storage mechanism towards the center, the storage space of the storage mechanism becomes smaller and smaller, and in order to adapt to the size of the sample box, the central region of the storage mechanism is not effectively utilized, resulting in waste of space.

[0121] Therefore, some embodiments of the present application are provided with a transfer component on the inner side of the innermost ring-shaped storage mechanism to transfer the sample box on the storage component, so that the transfer of the sample box on the plurality of storage components can be realized; the transfer component occupies the inner side space of the innermost ring-shaped storage mechanism, without occupying additional space, which is beneficial to further improve the compactness of the structure of the cryopreservation device.

[0122] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0123] In combination with Figure 1 and Figure 2 , some embodiments of the present application provide a cryopreservation device for cryopreservation of biological samples and other medical materials.

[0124] The cryopreservation device can include a box assembly 100, which is an appearance component of the cryopreservation device, and is configured to form a storage chamber for storing biological samples, an installation chamber for driving components of the cryopreservation device, an operation chamber for biological samples, and the like.

[0125] In some embodiments, the box assembly 100 is configured to form a storage cavity 101 configured to store the sample box 10. The sample box 10 is a container for storing biological samples, and is illustrated as a cuboid box in the drawings of the embodiments of the present application, but is not limited to the shape and structure of the sample box 10.

[0126] Generally, the temperature in the storage cavity 101 is low, for example, -80°C. If the sample box 10 is directly transferred between the storage cavity 101 and the external environment, the sample box 10 is prone to frost; and the large temperature difference is not conducive to the storage quality of the sample, and also causes the temperature fluctuation of the storage cavity 101.

[0127] Therefore, in some embodiments, the box assembly 100 is further configured to form a buffer cavity 102, and the storage temperature of the buffer cavity 102 is higher than that of the storage cavity 101. Of course, the storage temperature of the buffer cavity 102 is lower than zero degrees Celsius. For example, the storage temperature of the buffer cavity 102 is -30°C, -40°C, etc.

[0128] In some embodiments, the cryogenic device includes two refrigeration systems, one of which is used to refrigerate the storage cavity 101, and the other of which is used to refrigerate the buffer cavity 102. In this way, the temperature of the storage cavity 101 and the buffer cavity 102 can be accurately controlled.

[0129] The buffer cavity 102 is located on the side of the storage cavity 101, which facilitates the taking and placing of samples. For example, the buffer cavity 102 is arranged on one side of the storage cavity 101 along a first direction (corresponding to the Y-axis direction in Figure 2

[0130] The buffer cavity 102 is configured to be selectively communicated with the storage cavity 101, so that the sample box 10 is transferred between the buffer cavity 102 and the storage cavity 101. In this way, the sample can be operated in the low-temperature environment of the buffer cavity 102, avoiding the frost of the sample box 10 affecting the sample operation. Moreover, the sample box 10 enters and exits the storage cavity 101 via the buffer cavity 102, which can not only reduce the influence of temperature shock on the storage quality of the sample, but also reduce the influence on the temperature in the storage cavity 101.

[0131] In some embodiments, in combination with Figure 3 and Figure 4 , the box assembly 100 is further configured to form a first taking and placing opening 103 configured to communicate the buffer cavity 102 with the external atmosphere, so that the sample box 10 can enter and exit the buffer cavity 102 via the first taking and placing opening 103.

[0132] For example, the first taking and placing opening 103 is located on the side of the buffer cavity 102 away from the storage cavity 101, so that there is sufficient space for taking and placing the sample box 10 through the first taking and placing opening 103. ​

[0133] In combination Figure 2 and Figure 3 , the cryogenic device can comprise a first insulation door 130 configured to open or close the first access opening 103. The first insulation door 130 can be opened under the operation of an operator; the first insulation door 130 can also be an electric door, which can be opened or closed under the control of the control device of the cryogenic device.

[0134] In combination Figure 2 , the first insulation door 130 closes the first access opening 103; in Figure 3 , the first insulation door 130 is driven to open the first access opening 103.

[0135] In some examples, the cryogenic device can comprise a sample taking and placing mechanism 30 configured to input or output the sample box 10 to the buffer cavity 102 through the first access opening 103. The sample taking and placing mechanism 30 is located outside the buffer cavity 102, facilitating the input of the sample box 10 into the buffer cavity 102 or the output of the sample box 10 in the buffer cavity 102 through the first access opening 103.

[0136] Exemplarily, the sample taking and placing mechanism 30 is configured to vertically lift the sample box 10 to input or output the sample box 10 to the buffer cavity 102 through the first access opening 103.

[0137] In some examples, the sample taking and placing mechanism 30 is configured to seal the first access opening 103 first, and then open the first access opening 103 by the first insulation door 130 to input or output the sample box 10 to the buffer cavity 102. Such an arrangement ensures the closure of the buffer cavity 102 and reduces the possibility of cold air leakage from the buffer cavity 102, thereby improving the stability of the temperature in the buffer cavity 102. It also reduces the possibility of condensation of water droplets or icing at the edge of the first access opening 103, thereby ensuring the reliability of the opening and closing of the first access opening 103.

[0138] In combination Figure 4 , the box assembly 100 is further configured to form a second access opening 104, which communicates the buffer cavity 102 and the storage cavity 101, and the sample box 10 is transferred between the storage cavity 101 and the buffer cavity 102 through the second access opening 104.

[0139] In combination Figure 2 , the cryogenic device can comprise a second insulation door 140 configured to open or close the second access opening 104. The second insulation door 140 is an electric door, which can be opened or closed under the control of the control device.

[0140] In some embodiments, the second insulation door 140 can include a door mounting fixed in the cabinet assembly 100.

[0141] The second insulation door 140 can include an insulation door body slidably mounted on the door mounting, and the insulation door body is vertically slidable.

[0142] The second insulation door 140 can include a door driving mechanism connected with the insulation door body, and the door driving mechanism is configured to drive the door body to slide relative to the door mounting, so as to align the insulation door body with the second access opening 104 to close the second access opening 104, or to misalign the insulation door body with the second access opening 104 to open the second access opening 104.

[0143] The door driving mechanism can include a motor and a transmission assembly, the motor is connected with the insulation door body through the transmission assembly, and the transmission assembly converts the rotation of the motor into the linear motion of the insulation door body. The transmission assembly can include a lead screw and a nut, and the transmission assembly can include a gear and a rack, etc.

[0144] In some embodiments, a guide sliding groove is arranged on the door mounting, and the insulation door body is provided with a guide matching part which is slidably mounted in the guide sliding groove to guide the movement of the insulation door body.

[0145] The guide sliding groove includes a vertical sliding groove and an inclined sliding groove connected with each other, and the inclined sliding groove is located at one end of the vertical sliding groove. When the insulation door body slides along the inclined sliding groove, the insulation door body is pressed against the cabinet wall forming the second access opening 104 to improve the sealing performance of the insulation door body.

[0146] Continuing to refer to Figure 1 In some embodiments, the cabinet assembly 100 includes a first cabinet 110 configured to form the storage cavity 101.

[0147] The first cabinet 110 can include a first cabinet shell which is an appearance part of the first cabinet 110.

[0148] The first cabinet 110 can include a first cabinet liner 111 configured to form the storage cavity 101. The first cabinet liner 111 is fixed inside the first cabinet shell. An installation cavity is formed between the first cabinet liner 111 and the first cabinet shell to install some functional components of the cryopreservation device, such as a refrigeration system, a driving device, etc.

[0149] The first cabinet 110 can include a first insulation part arranged between the first cabinet shell and the first cabinet liner 111 to serve as an insulation part for the storage cavity 101. The first insulation part includes a foaming structure, an insulation board, etc.

[0150] In some embodiments, the box assembly 100 comprises a second box 120 configured to form the buffer cavity 102 and the first access opening 103. The second box 120 is located at a side of the first box 110. As shown in Figure 1 the longitudinal direction of the first box 110, wherein the longitudinal direction can correspond to Figure 1 the Y-axis direction in the coordinate system shown in FIG. 1.

[0151] The second box 120 can comprise a second box shell as an appearance member of the second box 120.

[0152] The second box 120 can comprise a second box body 121 configured to form the buffer cavity 102. The second box body 121 is fixed inside the second box shell. An installation cavity is formed between the second box body 121 and the second box shell to install some functional components of the cryopreservation device, such as the sample taking and placing mechanism 30.

[0153] The second box 120 can comprise a second heat preservation member arranged between the second box shell and the second box body 121 to serve as a heat preservation function for the storage cavity 101. The second heat preservation member can comprise a foamed structure, a heat preservation plate, or the like.

[0154] In combination with Figure 1 , in some embodiments, a display member 122 is installed on the second box shell to display storage information of the samples. Currently, the display member 122 can also have a touch function to facilitate the operation of the operator.

[0155] In some embodiments, the second box 120 can be detachably connected with the first box 110, so that in the event of a power failure or the like, the first box 110 and the second box 120 can be detached, and the samples in the first box 110 can be transferred in an emergency, thereby improving the safety of the cryopreservation device.

[0156] In some embodiments, the first box 110 is also configured to form a first opening in communication with the storage cavity 101. The second cavity is also configured to form at least one second opening configured to communicate with the buffer cavity 102. When the second box 120 is connected with the first box 110, the first opening and the second opening are opposite to each other and jointly form the second access opening 104.

[0157] Continuing to refer to Figure 2 and Figure 3 , the buffer cavity 102 serves as an operation chamber of the sample box 10, and a pipetting mechanism 40 can be arranged in the buffer cavity 102. The pipetting mechanism 40 is configured to take out a set of sample tubes from the sample box 10 or place a set of sample tubes in the sample box 10.

[0158] A scanning mechanism 50 may be installed inside the buffer cavity 102. The scanning mechanism 50 is configured to scan the information of the sample tubes inside the sample box 10.

[0159] A transfer station 60 may be installed inside the buffer cavity 102, and the transfer station 60 is configured to transfer the sample box 10.

[0160] In some embodiments, the transfer table 60 is located below the pipe-picking mechanism 40, which is configured to move vertically (corresponding to...). Figure 3 The sample tube is raised and lowered (in the Z-axis direction) to select a set sample tube from the sample box 10 on the transfer table 60.

[0161] The scanning mechanism 50, the sample loading and unloading mechanism 30, and the second loading and unloading port 104 are all located on the side of the transfer table 60, facilitating the transfer table 60 to transfer samples between the scanning station, the first loading and unloading port 103, and the second loading and unloading port 104. For example, the scanning mechanism 50 and the sample loading and unloading mechanism 30 are located on opposite sides of the transfer table 60 along the second direction, and the second loading and unloading port 104 is located on one side of the transfer table 60 along the first direction.

[0162] The second direction is perpendicular to the first direction. The second direction corresponds to... Figure 3 In the X-axis direction, the first direction corresponds to Figure 3 In the Y-axis direction.

[0163] exist Figure 4 In the orientation shown, the scanning mechanism 50 and the sampling mechanism 30 are located on both sides of the transfer table 60 along the X-axis, and the second sampling port 104 is located on one side of the transfer table 60 along the Y-axis.

[0164] In some embodiments, the transfer table 60 is configured to move the sample box 10 in a horizontal plane to transfer the sample box 10 between the sample taking and placing mechanism 30, the second taking and placing port 104, the scanning mechanism 50, and the tube picking mechanism 40.

[0165] The horizontal plane is perpendicular to the vertical direction. The horizontal plane is the plane defined by the first and second directions. Figure 4 In the directions shown, the horizontal plane is the XY plane.

[0166] The transfer table 60 moves the sample box 10 in the horizontal plane, including moving the sample box 10 in a certain direction in the horizontal plane and rotating the sample box 10 in the horizontal plane, that is, rotating around a rotation axis perpendicular to the horizontal plane.

[0167] Thus, the cryopreservation device of this application embodiment, by setting up a transfer platform 60, enables the sample box 10 to be transferred between four stations: scanning, tube picking, sample taking and placing mechanism 30 and second taking and placing port 104. This not only simplifies the structural arrangement within the buffer cavity 102, but also improves the transfer efficiency of the sample box 10.

[0168] In Figures 1 to 4 The structure shown in the example of the first cabinet 110 comprising the cabinet assembly 100. The cabinet assembly 100 is configured to form a second access opening 104.

[0169] In some embodiments, in combination Figure 3 and Figure 4 The first access opening 103 and the scanning mechanism 50 are respectively located on both sides of the transfer table 60 along the second direction, and the second access opening 104 is located on one side of the transfer table 60 along the first direction.

[0170] In the embodiments of the present application, the position of the first access opening 103 is lower than the position of the transfer table 60, so the sample taking mechanism 30 is configured to move vertically to transfer the sample box 10 from the sample taking mechanism 30 to the transfer table 60. In this way, the sample taking mechanism 30 and the pipette mechanism 40 are configured to move vertically, and the transfer table 60 only needs to move in the horizontal plane to realize the transfer between the two sample taking positions, the pipette position and the scanning position, a total of four positions. This is conducive to simplifying the sample transfer structure in the buffer cavity.

[0171] Of course, in some embodiments, the position of the first access opening 103 can be at the same level as the platform of the transfer table 60 for accommodating the sample box 10, so that the sample taking mechanism 30 can push the sample box 10 from the side of the transfer table 60 away from the first access opening 103, at this time the sample taking mechanism 30 can move in the horizontal plane.

[0172] In some other embodiments of the present application, a plurality of first cabinets 110 can be provided, and the plurality of first cabinets 110 are arranged at intervals around the circumference of the second cabinet 120.

[0173] The cabinet assembly 100 is configured to form a plurality of second access openings 104, and each second access opening 104 communicates with one of the storage cavities 101 and the buffer cavity 102. In this way, the second cabinet 120 is configured to form a plurality of second openings, and each second opening is opposite to one of the first openings to form a second access opening 104.

[0174] In combination Figure 5 In some possible embodiments of the present application, two first cabinets 110 are provided, and the two first cabinets 110 are respectively arranged on both sides of the second cabinet 120 along a certain direction. The two first cabinets 110 are respectively arranged on both sides of the second cabinet 120 along the X-axis direction. At this time, the first access opening 103 and the scanning mechanism 50 can be arranged on both sides of the transfer table 60 along the Y-axis direction. In this way, the two sample taking positions, the pipette position and the scanning position are respectively arranged on the four sides of the transfer table 60, and the transfer space of the sample box 10 is sufficient.

[0175] In combinationFigure 6 In some possible embodiments of the present application, three first boxes 110 are arranged on three sides of the second box 120, and the first access opening 103 is arranged on the fourth side of the second box 120, facilitating the sample taking and placing operation. The scanning mechanism 50 can be arranged between any two of the four access openings. The four access openings include the three second access openings 104 and the first access opening 103.

[0176] In this embodiment, the transfer manipulator in the two first boxes 110 arranged along the X-axis direction moves along the X-axis direction to transfer the sample box 10 between the storage mechanism 200 and the transfer table 60; the transfer manipulator in the first box 110 arranged on one side of the transfer table 60 along the Y-axis direction moves along the Y-axis direction to transfer the sample box 10 between the storage mechanism 200 and the transfer table 60.

[0177] Through the above arrangement, the transfer table 60 of the embodiment of the present application is configured to rotate in the horizontal plane and move along a straight line to transfer the sample box 10 between the sample taking and placing mechanism 30, the second access opening 104, the scanning mechanism 50 and the tube picking mechanism 40, which not only makes the arrangement positions of the sample taking and placing mechanism 30, the second access opening 104 and the scanning mechanism 50 more flexible, but also allows multiple storage cavities 101 to be arranged to increase the storage space. In this way, one buffer cavity 102 can be matched with multiple storage cavities 101, and the transfer table 60 can be used to realize the transfer of the sample box 10 between the buffer cavity 102 and the multiple storage cavities 101, thereby expanding the storage space.

[0178] In some embodiments, the transfer table 60 can include a first moving mechanism configured to drive the sample box 10 to move in a direction in the horizontal plane.

[0179] In some embodiments, the transfer table 60 can include a rotating mechanism, an output end of the rotating mechanism being connected with the first moving mechanism; the rotating mechanism is configured to drive the first moving mechanism to rotate about a rotating axis.

[0180] The rotating axis is perpendicular to the horizontal plane (corresponding to the XY plane in the coordinate system shown in FIG. 1). Figure 4 The rotating axis is parallel to the vertical direction, and the vertical direction corresponds to the Z-axis direction in the coordinate system shown in FIG. 1. Figure 4

[0181] Under the action of the rotating mechanism, the first moving mechanism is configured to drive the sample box 10 to move along the X-axis. The rotating mechanism can also drive the first moving mechanism to rotate, so that the first moving mechanism is configured to drive the sample box 10 to move along the Y-axis. Under the action of the rotating mechanism, the first moving mechanism can drive the sample box 10 to move in any straight line direction in the XY plane.

[0182] ​In the embodiments of the present application, the rotating mechanism is configured to drive the first moving mechanism to rotate 360° around the rotating shaft, so that the first moving mechanism can drive the sample box 10 to move in any direction in the horizontal plane, improving the flexibility of the sample box 10 transfer.

[0183] In some embodiments, the transfer table 60 can include a second moving mechanism, the output end of the second moving mechanism is connected with the rotating mechanism, and the second moving mechanism is configured to drive the rotating mechanism and the first moving mechanism to move along the sample taking and placing direction, so as to drive the sample box 10 to move along the sample taking and placing direction.

[0184] In this way, the moving direction of the second moving mechanism is consistent with the arrangement direction of the buffer cavity 102 and the storage cavity 101, which facilitates the transfer table 60 to transfer the sample box 10 towards the storage cavity 101; and the second moving mechanism can also provide sufficient space for the rotation of the rotating mechanism, avoiding interference between the transfer table 60 and other components in the buffer cavity 102 when the transfer table 60 rotates.

[0185] Continuing to refer to Figure 2 and Figure 3 In some embodiments, the storage cavity 101 is provided with a storage component 20 for accommodating the sample box 10. The storage component 20 provides support for the space placement of the sample box 10 in the storage cavity 101.

[0186] The storage component 20 includes a plurality of storage mechanisms 200, for example, two, three, etc. The storage mechanism 200 is annular, and exemplarily, the storage mechanism 200 is circular, facilitating installation and rotation driving.

[0187] The storage mechanism 200 is configured to accommodate the sample box 10. Since the storage mechanism 200 is annular, the sample boxes 10 can be arranged in a circumferential direction of the storage mechanism 200, and a plurality of storage positions of the sample boxes 10 can be arranged in a height direction of the storage mechanism 200, so as to increase the storage capacity of the sample boxes 10.

[0188] The plurality of storage mechanisms 200 are coaxially arranged, and the plurality of storage mechanisms 200 are sequentially arranged inside and outside in a radial direction, so that the structure of the storage mechanism 200 is compact, facilitating to improve the storage capacity of the storage cavity 101.

[0189] In some specific implementations, the storage component 20 includes:

[0190] The first storage mechanism is annular, and the first storage mechanism is configured to store the sample box 10;

[0191] The second storage mechanism is annular, and the first storage mechanism is configured to store the sample box 10; the second storage mechanism is arranged on the outside of the first storage mechanism, and the second storage mechanism is coaxially arranged with the first storage mechanism.

[0192] Some embodiments of the present application set two storage mechanisms 200, which can increase the storage capacity of the storage cavity 101, and avoid the radial size of the storage component 20 being too large, resulting in the structure of the transfer component 70 in the storage cavity 101 being complex.

[0193] With reference to the above description Figure 2 and Figure 3 , the storage component 20 can further include a driving mechanism 300 configured to drive each storage mechanism 200 to rotate independently. For example, the driving mechanism 300 drives the first storage mechanism and the second storage mechanism to rotate.

[0194] Illustratively, the driving mechanism 300 is provided with one, and the driving mechanism 300 drives each storage mechanism 200 to rotate independently by setting a clutch, a transmission mechanism, etc., so that each driving mechanism 300 drives the storage mechanism 200 connected thereto to rotate without driving other storage mechanisms 200 to rotate, so that each storage mechanism 200 can rotate relative to other storage mechanisms 200. Such a setting can realize the rotation of multiple storage mechanisms 200 with fewer driving mechanisms 300.

[0195] Illustratively, the driving mechanism 300 is provided with multiple, and each driving mechanism 300 is connected to one storage mechanism 200; the driving mechanism 300 is configured to drive the storage mechanism 200 to rotate. Such a setting makes the structure of each driving mechanism 300 relatively simple, and is conducive to improving the rotation rate of the storage mechanism 200, thereby improving the transfer rate of the sample box 10.

[0196] The storage mechanism 200 is provided with a transfer channel, so that the transfer component 70 can realize the transfer of the sample box 10 between the buffer cavity 102 and the storage cavity 101 via the transfer channel.

[0197] Taking the storage cavity 101 provided with the first storage mechanism and the second storage mechanism sleeved on the outer side of the first storage mechanism as an example. When the target sample box on the second storage mechanism needs to be taken out, the driving mechanism of the second storage mechanism drives it to rotate, so that the target sample box rotates to the first direction; at the same time, the driving mechanism of the first storage mechanism drives it to rotate, so that the transfer channel of the first storage mechanism rotates to the first direction. Then, the transfer component 70 moves vertically to make the transfer component 70 opposite to the transfer channel; the transfer component 70 passes through the transfer channel of the first storage mechanism and receives the target sample box on the second storage mechanism.

[0198] In the above process, the driving mechanisms of the first storage mechanism and the second storage mechanism drive the storage mechanisms connected thereto to rotate independently, which can quickly make the target sample box correspond to the transfer component 70, improve the transfer rate of the sample box, and is also conducive to improving the rotation accuracy of the storage mechanism 200.

[0199] With reference to the foregoing Figure 2 and Figure 3 In some embodiments, the storage cavity 101 is further provided with a transfer component 70, which is configured to transfer the sample box 10 between the storage mechanism 200 and the buffer cavity 102.

[0200] The cryogenic storage device of the embodiments of the present application achieves the transfer of the sample box 10 between the storage cavity 101 and the buffer cavity 102 by providing the transfer component 70 in the storage cavity 101 and the transfer table 60 in the buffer cavity 102, and utilizing the transfer component 70 and the transfer table 60.

[0201] In some embodiments, the transfer component 70 is arranged inside the innermost circle of the storage mechanism 200. For example, when the storage component 20 includes a first storage mechanism and a second storage mechanism arranged outside the first storage mechanism, the transfer component 70 is arranged inside the first storage mechanism.

[0202] Here, the innermost circle of the storage mechanism 200 refers to the storage mechanism 200 closest to the vertical center line of the storage mechanism 200. The extension direction of the vertical center line is parallel to the Z-axis direction.

[0203] Through the above arrangement, the plurality of annular storage mechanisms 200 are sequentially arranged outside the transfer component 70 in the radial direction, and the storage mechanism 200 closest to the transfer component 70 is the innermost circle of the storage mechanism 200.

[0204] Since the annular storage mechanism 200 has a smaller and smaller storage space from the edge of the storage mechanism 200 to the center thereof, the central region of the storage mechanism 200 is usually provided with a guide structure and the like and is not effectively utilized, resulting in a waste of space.

[0205] In some embodiments of the present application, the transfer component 70 is arranged inside the innermost circle of the storage mechanism 200, and the transfer component 70 can transfer all the sample boxes 10 by spanning the radius of the storage component 20, so that the transfer component 70 does not need to be provided with an excessively long conveying distance, which is beneficial to improve the stability of the transfer component 70; moreover, the transfer component 70 utilizes the space inside the storage mechanism 200 without occupying other spaces in the storage cavity 101, which is beneficial to improve the compactness of the components inside the storage cavity 101.

[0206] In some embodiments of the present application, the transfer component 70 is configured to move along the vertical direction and the first direction to transfer the sample box 10 between the buffer cavity 102 and the storage mechanism 200.

[0207] Here, the vertical direction is perpendicular to the first direction. The vertical direction can correspond to Figure 3The first direction corresponds to the Y-axis direction in the figure.

[0208] In some embodiments of the present application, the transfer component 70 is configured to move vertically, in combination with the rotation of the storage mechanism 200, so that the transfer component 70 can output or store the sample box 10 at any height of the storage mechanism 200.

[0209] In some embodiments of the present application, the transfer component 70 is configured to move along the first direction, which is parallel to a radial direction of the storage mechanism 200, so that the transfer component 70 can transfer the sample box 10 along the first direction on the storage mechanism 200. Since the storage cavities 101 and the buffer cavities 102 are arranged along the first direction, the transfer component 70 configured to move along the first direction can transfer the sample box 10 between the storage cavities 101 and the buffer cavities 102.

[0210] Thus, the cryogenic storage device of the embodiments of the present application improves the storage capacity in the storage cavities 101 by arranging multiple annular storage mechanisms 200, and improves the compactness of the structure of the cryogenic storage device by arranging the multiple storage mechanisms 200 coaxially and sequentially from the inside to the outside along the radial direction. By arranging the transfer component 70 inside the innermost storage mechanism 200, the sample box 10 can be transferred between the buffer cavities 102 and the storage cavities 101 by the transfer component 70, and the space inside the storage mechanism 200 can be utilized without occupying other space in the storage cavities 101, which is conducive to improving the compactness of the structure of the internal components of the storage cavities 101.

[0211] In some embodiments of the present application, the transfer component 70 is configured to move vertically, in combination with the rotation of the storage mechanism 200, so that the transfer component 70 can output or store the sample box 10 at any height of the storage mechanism 200.

[0212] In some embodiments of the present application, the cryogenic storage device divides the movement of the sample box 10 in the storage cavities 101 in the three-dimensional space into the storage mechanism 200 and the transfer component 70, utilizes the rotation of the storage mechanism 200 to move the sample box 10 horizontally, and utilizes the vertical movement and the movement along the first direction of the transfer component 70 to move the sample box 10 in the height direction and the first direction, thereby simplifying the structure of the transfer component 70 and the storage component 20.

[0213] In some embodiments of the present application, the driving mechanism 300 drives each storage mechanism 200 to rotate independently to adjust the moving direction of the target position towards the transfer component 70; then the transfer component 70 is configured to move vertically to make the transfer component 70 relative to the target position of the storage mechanism 200; the transfer component 70 is also configured to move in the first direction to transport the sample box 10 to the target position on the storage mechanism 200 or take out the sample box 10 on the target position. The transfer component 70 is located inside the annular storage mechanism 200, and its position in the horizontal plane is fixed. By rotating the storage mechanism 200, the sample box 10 is moved to the corresponding position of the transfer component 70; then combined with the lifting of the transfer component 70, the position of the sample box 10 is determined, and only the movement of the transfer component 70 in the first direction is needed to realize the taking and placing of the sample box 10, which reduces the difficulty of taking and placing.

[0214] In combination Figure 7 In some embodiments, the storage mechanism 200 can include an upper turntable member 210 in the form of a ring. Exemplarily, the upper turntable member 210 is in the form of a circular ring.

[0215] The storage mechanism 200 can include a lower turntable member 220 in the form of a ring, which is vertically spaced below the upper turntable member 210. Exemplarily, the lower turntable member 220 is in the form of a circular ring, and the lower turntable member 220 is parallel to the upper turntable member 210.

[0216] The storage mechanism 200 can include a plurality of storage racks 230 fixed between the upper turntable member 210 and the lower turntable member 220, and the plurality of storage racks 230 are spaced along the circumference of the upper turntable member 210.

[0217] In some embodiments of the present application, the storage mechanism 200 increases the storage capacity of the cryopreservation device by arranging a plurality of storage racks 230 between the upper turntable member 210 and the lower turntable member 220, and increasing the number of storage racks 230.

[0218] Exemplarily, the storage racks 230 arranged in the same layer as the transfer component 70 and in the first direction are default, thereby forming a transfer channel.

[0219] In some embodiments, in combination Figure 7The storage mechanism 200 can include at least one intermediate turntable member 260, which is annular and located between the upper turntable member 210 and the lower turntable member 220, so as to improve the structural stability of the storage mechanism 200. Moreover, the storage rack 230 can be arranged in two sections along the vertical direction, one of which is located between the upper turntable member 210 and the intermediate turntable member 260, and the other of which is located between the lower turntable member 220 and the intermediate turntable member 260, so as to shorten the height of the storage rack 230 and improve the stability of the storage rack 230.

[0220] Exemplarily, the intermediate turntable member 260 can be provided in plurality, and the plurality of intermediate turntable members 260 are arranged along the vertical direction at intervals, so as to further improve the structural stability of the storage mechanism.

[0221] With reference back to Figure 7 The storage mechanism 200 includes a plurality of connecting rods 270. The plurality of connecting rods 270 can be arranged at intervals along the circumferential direction of the turntable member.

[0222] The two ends of the connecting rod 270 are connected with the turntable member respectively. For example, the two ends of the connecting rod 270 are connected with the intermediate turntable member 260 and the upper turntable member 210 respectively, and for another example, the two ends of the connecting rod 270 are connected with the intermediate turntable member 260 and the lower turntable member 220 respectively.

[0223] The storage mechanism 200 of some embodiments improves the structural stability of the storage mechanism 200 by providing the plurality of connecting rods 270.

[0224] With reference back to Figure 7 In some embodiments, the storage mechanism further includes a support disc 240, which can be disc-shaped and used for supporting the lower turntable member 220 and the structure thereon.

[0225] With reference back to Figure 8 The support disc 240 is fixed in the storage cavity 101, and the support disc 240 is located below the lower turntable member 220, so as to support the lower turntable member 220 and the structure thereon.

[0226] In some embodiments, the support disc 240 is provided with a roller member 250, which is configured to support the lower turntable member 220 and limit the rotation of the lower turntable member 220 about the center thereof.

[0227] In this way, the support disc 240 can stably support the lower turntable member 220 and reduce the rotation resistance of the lower turntable member, so that the storage mechanism 200 can rotate smoothly.

[0228] In some embodiments, the roller member 250 comprises a plurality of load rollers 251 for supporting the lower turntable member 220 and the structure thereon. The plurality of load rollers 251 are rotatably mounted on the support disc 240 and are spaced along the circumference of the support disc 240. The rotation axis of the load rollers 251 extends along the radial direction of the support disc 240.

[0229] In some embodiments, the roller member 250 can comprise a plurality of first guide rollers 252 spaced along the circumference of the support disc 240. The first guide rollers 252 are rotatably mounted on the support disc 240. The rotation axis of the first guide rollers 252 extends along the vertical direction. The plurality of first guide rollers 252 are in contact with the lower turntable member 220 to restrict the rotation of the lower turntable member 220 about its center.

[0230] In some embodiments, the bottom surface of the lower turntable member 220 is fixed with a gear ring 330 for connecting with the output end of the driving mechanism 300 to drive the storage mechanism 200 to rotate.

[0231] In some embodiments, the tooth surface of the gear ring 330 of the first storage mechanism is located on the inner side of the gear ring 330, and the tooth surface of the gear ring 330 of the second storage mechanism is located on the outer side of the gear ring 330. In this way, the roller member 250 of the two storage mechanisms 200 is arranged between the two gear rings 330, which is beneficial to improve the compactness of the storage mechanism 200.

[0232] The first guide rollers 252 are in indirect contact with the lower turntable member 220 by contacting the gear ring 330, thereby restricting the rotation of the lower turntable member 220 about its center.

[0233] The first guide rollers 252 are located on the side of the gear ring 330 away from the tooth surface thereof, so that the stability of the contact between the first guide rollers 252 and the gear ring 330 is improved, thereby improving the guiding effect of the first guide rollers 252.

[0234] In combination Figure 7 In some embodiments, the storage cavity 101 is further provided with a plurality of second guide rollers 281 fixed to the cavity wall of the storage cavity 101 and spaced along the circumference of the upper turntable member 210. The rotation axis of the second guide rollers 281 extends along the vertical direction. The plurality of second guide rollers 281 are in contact with the upper turntable member 210 to restrict the rotation of the upper turntable member 210 about its center. Moreover, by providing the second guide rollers 281, the possibility of deformation of the storage mechanism 200 due to stress is reduced.

[0235] Referring again to Figure 7In some embodiments, a plurality of third guide rollers 282 are arranged in the storage cavity, and the plurality of third guide rollers 282 are fixed to the cavity wall of the storage cavity and are arranged along the circumference of the intermediate rotating disc member 260. The rotation axis of the third guide rollers 282 is arranged vertically. The plurality of third guide rollers 282 are in contact with the intermediate rotating disc member 260 to limit the rotation of the intermediate rotating disc member 260 along the center thereof. By arranging the third guide rollers 282, the possibility of deformation of the storage mechanism 200 due to stress is reduced.

[0236] The second guide rollers 281 and the third guide rollers 282 are arranged on the inner side of the rotating member of the first storage mechanism and on the outer side of the second storage mechanism. In this way, the radial distance between the first storage mechanism and the second storage mechanism can be reduced, and the radial dimension of the storage component 20 can be reduced, thereby reducing the moving distance of the transfer component 70 in the first direction.

[0237] In other embodiments, the roller member 250 can include a plurality of V-shaped rollers arranged along the circumference of the lower rotating disc member 220. The side of the ring gear 330 away from the tooth surface is provided with an annular slide rail, and at least part of the annular slide rail is accommodated in the V-shaped groove of the V-shaped roller. Through the cooperation of the annular slide rail of the ring gear 330 and the V-shaped roller, the V-shaped roller can not only support the lower rotating member and the structure thereon, but also limit the lower rotating member.

[0238] In combination with Figure 3 , Figure 7 and Figure 9 In some embodiments, the driving mechanism 300 can include a rotating driver 310 configured to drive the rotation of the storage mechanism 200. The rotating driver 310 provides a rotating driving force for the rotation of the storage mechanism 200.

[0239] Exemplarily, the driving mechanism 300 can be an electric motor.

[0240] The rotating driver 310 is mounted on the outside of the storage cavity 101, so that the rotating driver 310 is located outside the low-temperature environment of the storage cavity 101, which is beneficial to guarantee the service life of the rotating driver 310, and does not need to select a low-temperature resistant driver, which is beneficial to reduce the cost of the driving mechanism 300.

[0241] In some embodiments, the driving mechanism 300 can include a rotating transmission assembly connected to the output end of the rotating driver 310 and the storage mechanism 200, respectively, to transmit the driving force of the rotating driver 310 to the storage mechanism 200.

[0242] The rotation transmission assembly can include a first gear 321 located between the lower turntable member 220 and the support disc 240. The first gear 321 is engaged with the gear ring 330.

[0243] The rotation transmission assembly can include a first transmission shaft 322 connected with the first gear 321 to drive the first gear 321 to rotate. The first transmission shaft 322 passes through a through hole on the support disc 240, a through hole on the cavity wall of the storage cavity 101 to the outside of the storage cavity 101. A sealing structure is arranged between the first transmission shaft 322 and the through hole on the cavity wall of the storage cavity 101 to improve the sealing performance of the storage cavity 101.

[0244] The first transmission shaft 322 can be directly connected with the rotation driver 310, so that the rotation driver 310 is located below the storage cavity 101. Alternatively, the first transmission shaft 322 is connected with the rotation driver 310 through a transmission assembly, so that the rotation driver 310 is located at the side of the storage cavity 101, to reduce the vertical dimension of the cryopreservation device.

[0245] In some embodiments, the part of the first transmission shaft 322 extending to the outside of the storage cavity 101 is provided with a first transmission wheel 323, and the output shaft of the rotation driver 310 is provided with a second transmission wheel. A first transmission belt 324 or a first transmission chain is wound between the first transmission wheel 323 and the second transmission wheel. In this way, the rotation driver 310 drives the second transmission wheel to rotate, and the second transmission wheel and the first transmission shaft 322 are driven to rotate through the first transmission belt 324, so that the gear ring 330 is driven to rotate through the first gear 321, and the rotation of the storage mechanism 200 is realized.

[0246] The structure and function of the transfer component 70 in some embodiments of the present application will be described in detail below with reference to the accompanying drawings.

[0247] Referring to Figure 10 , in some embodiments, the transfer component 70 includes a fixing member 71 mounted to the inner side of the innermost ring of the storage mechanism 200.

[0248] Exemplarily, the fixing member 71 is in the form of a plate, which can provide a larger mounting area and reduce the mounting space occupied by the fixing member 71.

[0249] In some embodiments, referring to Figure 3 , the transfer component 70 can include a lifting mechanism 500 configured to drive the sample box 10 to move vertically.

[0250] Referring to Figure 3 , Figure 10 and Figure 11 , the lifting mechanism 500 includes a lifting transmission assembly 510 connected with the fixing member 71.

[0251] The lifting driver 520 is installed outside the storage cavity 101, and the lifting driver 520 is connected with the lifting transmission assembly 510. The lifting driver 520 drives the fixed part 71 to move vertically through the lifting transmission assembly 510.

[0252] The lifting driver 520 provides lifting driving force for the fixed part 71. The lifting driver can be a motor.

[0253] The lifting driver 520 is located outside the storage cavity 101, so that the lifting driver 520 is located outside the low-temperature environment of the storage cavity 101, which is beneficial to guarantee the service life of the lifting driver 520, and does not need to select a low-temperature-resistant driver, which is beneficial to reduce the cost of the transfer part 70.

[0254] In some embodiments of the present application, the lifting transmission assembly 510 comprises:

[0255] The lead screw 511 extends vertically, and the lead screw 511 is connected with the lifting driver 520.

[0256] The nut 512 is formed on the fixed part 71, and the nut 512 is threadedly connected with the lead screw 511.

[0257] In combination with Figure 9 The lifting transmission assembly 510 can further comprise a second transmission shaft 540. The bottom end of the lead screw 511 is connected with the second transmission shaft 540. The second transmission shaft 540 passes through the through hole on the support disc 240 and the through hole on the cavity wall of the storage cavity 101 to the outside of the storage cavity 101. A sealing structure is arranged between the second transmission shaft 540 and the through hole on the cavity wall of the storage cavity 101 to improve the sealing performance of the storage cavity 101.

[0258] The connection mode of the second transmission shaft 540 and the output end of the lifting driver 520 can refer to the connection mode of the first transmission shaft 322 and the output end of the rotating driver 310. In this way, the lifting driver 520 and the rotating driver 310 can be arranged at similar positions, which is beneficial to assembly and maintenance.

[0259] Therefore, the lifting transmission assembly 510 of some embodiments of the present application converts the rotation of the lifting driver 520 into the linear movement of the fixed part 71 along the vertical direction through the arrangement of the lead screw 511 and the nut 512, transmits the driving force outside the storage cavity 101 to the inside of the storage cavity 101, and makes the structure of the lifting mechanism 500 compact.

[0260] The lifting mechanism 500 of some embodiments of the present application provides lifting driving force for the fixed part 71 through the lifting driver 520, and transmits the driving force outside the storage cavity 101 to the inside of the storage cavity 101 through the lifting transmission assembly 510.

[0261] With reference to the foregoing Figure 10 And Figure 11 In some embodiments, the transfer component 70 can further include a guide structure configured to guide the lifting of the fixing member 71.

[0262] The guide structure includes a guide rod 530 extending in the vertical direction, and a guide hole 711 provided on the fixing member 71, the guide rod 530 being disposed in the guide hole 711, and the guide hole 711 and the guide rod 530 cooperating to improve the straightness of the vertical movement of the fixing member 71.

[0263] The bottom end of the guide rod 530 can be fixed to the support disc 240, and the top end of the guide rod 530 can be fixed to the top wall of the storage cavity 101.

[0264] In some embodiments, the guide hole 711 can be provided with a plurality of guide rods 530 disposed therein. The plurality of guide holes 711 are arranged at the edges of the fixing member 71 to avoid interference of the guide rod 530 with the movement of the transfer component 70.

[0265] For example, the plurality of guide holes 711 can be symmetrically arranged on both sides of the second direction, which is perpendicular to the first direction, i.e., the second direction is perpendicular to the movement direction of the transfer component 70. This can not only avoid interference of the guide rod 530 with the movement of the transfer component 70, but also balance the force acting on the fixing member 71.

[0266] For example, the first direction corresponds to the Y-axis direction, and the second direction corresponds to the X-axis direction. Figure 11

[0267] For example, the guide hole 711 is provided with four guide holes, two of which are arranged on each side of the second direction. The nut 512 is arranged between the two guide holes on one side.

[0268] With reference to the foregoing Figure 10 And Figure 11 The transfer component 70 of some embodiments of the present application can further include a translation mechanism 400 configured to move in the first direction to transfer the sample box 10 in the first direction.

[0269] In some embodiments, the translation mechanism 400 can include a first moving assembly 410 mounted to the fixing member 71. The first moving assembly 410 is configured to move in the first direction to transport the sample box 10 in the first direction.

[0270] In some embodiments, in combination with Figure 12 ​The translation mechanism 400 can comprise a second moving assembly 420 connected to the first moving assembly 410. The second moving assembly 420 is configured to move along the first direction.

[0271] The second moving assembly 420 can be arranged above the first moving assembly 410, which facilitates the arrangement of the guide and connection between the second moving assembly 420 and the first moving assembly 410.

[0272] The second moving assembly 420 is provided with a shovel 440 to accommodate the sample box 10.

[0273] In the vertical direction, the second moving assembly 420 is higher than the first moving assembly 410. Such arrangement can reduce the installation space of the translation mechanism 400 in the plane of the fixing member 71, so that the translation mechanism 400 is arranged more compactly.

[0274] In some embodiments, referring to Figure 3 The translation mechanism 400 can comprise a translation driving assembly 430 connected to the first moving assembly 410. The translation driving assembly 430 is configured to drive the first moving assembly 410 and the second moving assembly 420 to move along the first direction.

[0275] In some embodiments of the present application, the translation mechanism 400 is provided with the translation driving assembly 430 to drive the first moving assembly 410 and the second moving assembly 420 to move along the first direction, so as to convey the sample box 10 along the first direction. Moreover, the translation mechanism 400 of the present embodiment is provided with two moving assemblies, so that the translation mechanism 400 has two levels of movement, which increases the moving distance of the translation mechanism 400 along the first direction, so that the storage device is provided with the multi-turn storage mechanism 200, which increases the storage capacity. The translation mechanism 400 can transfer the sample box 10 in the storage cavity 101 to the buffer cavity 102.

[0276] Since the transfer station 60 is provided with the second moving mechanism configured to drive the rotating mechanism and the first moving mechanism to move along the first direction, the transfer station 60 can drive the sample box 10 to move along the first direction through the second moving mechanism. Moreover, under the driving of the rotating mechanism, the first moving mechanism can drive the sample box 10 to move along the first direction, so as to increase the moving distance of the sample box 10 along the first direction.

[0277] The transport table 60 is configured to increase the moving distance of the sample box 10 along the first direction by the second moving mechanism and the first moving mechanism. In some possible implementations, the transport table 60 is configured to deliver the sample box 10 into the storage cavity 101 and onto the storage mechanism 200 at the outermost circle of the storage cavity 101. In this way, the moving stroke of the translation mechanism 400 can be shortened, and the structure of the translation mechanism 400 is more simple and stable, and the delivery of the sample box 10 is more stable.

[0278] Therefore, the translation mechanism 400 of the transport component 70 of the cryopreservation device provided in the embodiments of the present application is configured to move in two stages along the first direction by the two moving assemblies, and the sample box 10 is driven along the first direction by the second moving mechanism of the transport table 60 and the first moving mechanism, so that the sample box 10 has sufficient moving distance along the first direction, and the storage mechanism 200 can be arranged in multiple circles.

[0279] In some embodiments, the first moving assembly 410 can include a first transmission wheel set 411 rotatably mounted to the fixed member 71, and the first transmission wheel set 411 is connected to the translation driving assembly 430. Figure 11

[0280] The first moving assembly 410 can include a first flexible transmission member 412 arranged around the first transmission wheel set 411, and at least part of the first flexible transmission member 412 extends along the first direction. The first flexible transmission member 412 can be a transmission chain, a transmission belt, or the like.

[0281] The translation driving assembly 430 drives at least part of the first flexible transmission member 412 to move along the first direction by the first transmission wheel set 411.

[0282] The second moving assembly 420 is connected to the part of the first flexible transmission member 412 extending along the first direction. In this way, the translation driving assembly 430 drives at least part of the first flexible transmission member 412 to move along the first direction by the first transmission wheel set 411, thereby driving the second moving assembly 420 to move along the first direction, and achieving one-stage movement of the translation mechanism 400.

[0283] In some embodiments, the first transmission wheel set 411 can include a driving wheel 4111 provided with an axle hole 4112. The driving wheel 4111 is located above the fixed member 71, and the fixed member 71 is provided with a through hole at a position corresponding to the axle hole 4112, so that an axle passing through the axle hole 4112 can pass through the through hole.

[0284] ​The driving wheel 4111 can be mounted on the side of the fixing member 71 away from the nut 512 and between the two guide holes 711. In this way, the driving structure of the driving wheel 4111 can be prevented from interfering with the lead screw 511, and the structure on the fixing member 71 can be more symmetrical, thereby improving the stability of the fixing member 71 under stress.

[0285] The first transmission wheel set 411 can include two driven wheels 4113, which are arranged in the first direction and at intervals, so that at least part of the first flexible transmission member 412 extends in the first direction. In the first direction, the two driven wheels 4113 are respectively located on the two sides of the driving wheel 4111.

[0286] The two driven wheels 4113 are rotatably mounted on the fixing member 71, and the rotation axes of the two driven wheels 4113 extend in the vertical direction.

[0287] The driving wheel 4111 is located on the side of the center line of the two driven wheels 4113 away from the nut 512, so that the driving of the translation mechanism 400 and the driving of the lifting mechanism 500 are kept away from each other and interference is avoided.

[0288] The first transmission wheel set 411 can further include two limiting wheels 4114, which are rotatably mounted on the fixing member 71 and have rotation axes extending in the vertical direction.

[0289] The two limiting wheels 4114 are arranged in the first direction and at intervals; and in the first direction, the two limiting wheels 4114 are located on the two sides of the driving wheel 4111. The interval of the centers of the two limiting wheels 4114 in the first direction is smaller than the interval of the centers of the two driven wheels 4113 in the first direction. In the second direction, the two limiting wheels 4114 are located between the center line of the driving wheel 4111 and the two driven wheels 4113.

[0290] The first flexible transmission member 412 is wound around the driving wheel 4111, the two limiting wheels 4114 and the two driven wheels 4113, wherein the driving wheel 4111 and the two driven wheels 4113 cooperate with the inner side of the first flexible transmission member 412, and the two limiting wheels 4114 cooperate with the outer side of the first flexible transmission member 412.

[0291] The first moving assembly 410 of the embodiment of the present application transmits the driving force of the translation driving assembly 430 by arranging the driving wheel 4111, extends at least part of the first flexible transmission member 412 in the first direction by arranging the two driven wheels 4113, and limits the extension direction of the first flexible transmission member 412 by arranging the two limiting wheels 4114, so that the first flexible transmission member 412 has greater contact with the driving wheel 4111 and the two driven wheels 4113, thereby ensuring the reliability of the transmission of the first moving assembly 410.

[0292] The centers of the two limiting wheels 4114 and the center of the driving wheel 4111 have a first interval in the first direction; the centers of the two driven wheels 4113 and the center of the driving wheel 4111 have a second interval in the first direction, the second interval is greater than the first interval, so that the two limiting wheels 4114 are closer to the driving wheel 4111 than the driven wheels 4113.

[0293] Some embodiments of the application set the interval of the two driven wheels 4113 in the first direction to be larger, so that the first flexible transmission member 412 has a larger first direction extension distance, thereby increasing the movement stroke of the first movement; by setting the interval of the two limiting wheels 4114 in the first direction to be smaller, the first flexible transmission member 412 can have a larger cooperation length with the driving wheel 4111, and also can have a larger cooperation length with the two driven wheels 4113, thereby improving the reliability of the first movement assembly 410 and reducing the possibility of the first flexible transmission member 412 being detached from the first transmission wheel set.

[0294] In combination Figure 3 , Figure 10 and Figure 11 , in some embodiments, the translation driving assembly 430 includes a translation transmission shaft 432 extending in the vertical direction, the translation transmission shaft 432 is arranged through the shaft hole 4112, so that the driving wheel 4111 can slide along the transmission shaft.

[0295] A translation driver 431 is mounted outside the storage cavity 101; the translation driver 431 is connected with the translation transmission shaft 432, and the translation driver 431 is configured to drive the driving wheel 4111 to rotate through the translation transmission shaft 432.

[0296] The translation driver 431 can be an electric motor.

[0297] In this way, when the lifting mechanism 500 drives the fixed part 71 to move vertically, the shaft hole 4112 moves along the translation transmission shaft 432, so that the cooperation between the translation transmission shaft 432 and the driving wheel 4111 does not affect the vertical movement of the fixed part 71.

[0298] Moreover, the translation transmission shaft 432 can also drive the driving wheel 4111 to rotate. That is, the cooperation between the translation transmission shaft 432 and the shaft hole 4112 can make the translation transmission shaft 432 drive the driving wheel 4111 to rotate, and the driving wheel 4111 can also move along the translation transmission shaft 432.

[0299] Exemplarily, the cross-sectional shape of the translation transmission shaft 432 is non-circular, and the cross-sectional shape of the shaft hole 4112 is the same as that of the translation transmission shaft 432, so that the translation transmission shaft 432 can drive the driving wheel 4111 to rotate, and the driving wheel 4111 can also move along the translation transmission.

[0300] As shown in Figure 10 and Figure 11 , the translation transmission shaft 432 is a square shaft, and the shaft hole 4112 is a square hole. This is only a schematic illustration of the cross-sectional shape of the translation transmission shaft 432 and the shape of the shaft hole 4112, and is not a limitation on the shapes of the two.

[0301] In some embodiments of the present application, the translation driver 431 is located outside the storage cavity 101, so that the translation driver 431 can be located outside the low-temperature environment of the storage cavity 101, which is conducive to ensuring the service life of the translation driver 431, and does not need to select a low-temperature-resistant driver, which is conducive to reducing the cost of the transfer component 70.

[0302] In some embodiments, in combination with Figure 9 , the translation driving assembly 430 can include a third transmission shaft 433, which is connected to the bottom end of the translation transmission shaft 432, and the third transmission shaft 433 passes through a through hole on the support disc 240 and a through hole on the cavity wall of the storage cavity 101 to the outside of the storage cavity 101. A sealing structure is provided between the third transmission shaft 433 and the through hole on the cavity wall of the storage cavity 101 to improve the sealing performance of the storage cavity 101.

[0303] The connection mode of the third transmission shaft 433 and the output end of the translation driver 431 can refer to the connection mode of the first transmission shaft 322 and the output end of the rotation driver 310, so that the translation driver 431 and the rotation driver 310 can be arranged at similar positions, which is convenient for assembly and maintenance.

[0304] Referring to Figure 11 and Figure 12 , in some embodiments, the second moving assembly 420 includes a moving table 421, which is slidably installed on the fixing member 71.

[0305] The moving table 421 is connected to the part of the first flexible transmission member 412 extending in the first direction, so that the first flexible transmission member 412 can drive the moving table 421 to move in the first direction.

[0306] In some embodiments, the translation mechanism 400 can further include a first connecting member 450 connecting the moving table 421 and the first flexible transmission member 412. In this way, when the first flexible transmission member 412 moves in the first direction, the moving table 421 is driven to move in the first direction by the first connecting member 450.

[0307] In some embodiments, the second moving assembly 420 includes a second transmission wheel set 422 rotatably installed on the moving table 421.

[0308] The second moving assembly 420 can include a second flexible transmission member 423, at least a portion of which extends along the first direction, and the second flexible transmission member 423 is arranged around the second transmission wheel set 422.

[0309] The second flexible transmission member 423 can be a transmission chain or a transmission belt, etc.

[0310] The second transmission wheel set 422 causes at least a portion of the second flexible transmission member 423 to extend along the first direction. In some embodiments, the second transmission wheel set 422 includes two third transmission wheels 4221 rotatably mounted on the moving platform 421, and the rotation axes of the two third transmission wheels 4221 extend along the vertical direction. The two third transmission wheels 4221 are arranged along the first direction, and the second flexible transmission member 423 is arranged around the two third transmission wheels 4221, so that at least a portion of the second flexible transmission member 423 extends along the first direction.

[0311] The portion of the second flexible transmission member 423 extending along the first direction is connected with the fixed member 71 and the shovel disc 440, respectively. In this way, when the first moving assembly 410 drives the moving platform 421 to move along the first direction, the second transmission wheel set 422, the second flexible transmission member 423 and the shovel disc 440 on the moving platform 421 all move along the first direction. Since the portion of the second flexible transmission member 423 extending along the second direction is connected with the fixed member 71, the second flexible transmission member 423 is driven to move along the first direction relative to the moving platform 421, thereby driving the shovel disc 440 to move relative to the moving platform 421, realizing the secondary movement of the translation mechanism 400.

[0312] In some embodiments of the present application, under the action of the two third transmission wheels 4221, the second flexible transmission member 423 has two straight line segments, both of which extend along the first direction and are spaced apart along the second direction. The straight line segment close to the first moving assembly 410 is fixedly connected with the fixed member 71, and the other straight line segment is fixedly connected with the shovel disc 440.

[0313] In some embodiments, the straight line segment of the second flexible transmission member 423 is close to the first flexible transmission member 412 along the second direction, and the straight line segment is located above the straight line segment of the first flexible transmission member 412, so that the first connecting member 450 has a relatively simple and compact structure to connect the first flexible transmission member 412 and the moving platform 421.

[0314] Through the above arrangement, the connection positions of the fixed member 71 and the second flexible transmission member 423, and the connection positions of the shovel disc 440 and the second flexible transmission member 423 are located on both sides of the first connecting line, where the first connecting line is the connecting line of the centers of the two third transmission wheels 4221. In this way, the shovel disc 440 has a larger moving distance along the first direction.

[0315] In some embodiments, the combination Figure 11 and Figure 12 The translation mechanism 400 can include a second connecting member 460 fixed to the fixed member 71 and connected with the second flexible transmission member 423. By limiting the second flexible transmission member 423, the second flexible transmission member 423 is moved relative to the moving platform 421, and the secondary movement of the translation mechanism 400 is realized.

[0316] The translation mechanism 400 can include a third connecting member 470 connecting the shovel disc 440 and the second flexible transmission member 423. In this way, when the second flexible transmission member 423 is moved relative to the moving platform 421 in the first direction, the third connecting member 470 drives the shovel disc 440 to move relative to the moving platform 421 in the first direction, and the secondary movement of the translation mechanism 400 is realized.

[0317] Referring to Figure 11 and Figure 12 In some embodiments, a first guide structure is arranged between the fixed member 71 and the moving platform 421, and the first guide structure is configured to guide the moving platform 421 to move in the first direction, and improve the straightness of the moving platform 421 moving in the first direction.

[0318] For example, the fixed member 71 is provided with a first guide rail 712 extending in the first direction. The bottom of the moving platform 421 is provided with a first sliding block slidably mounted on the first guide rail 712. The movement of the moving platform 421 in the first direction is guided by the cooperation of the first sliding block and the first guide rail 712.

[0319] For example, in combination Figure 13 The fixed member 71 is provided with a first guide rail 712 extending in the first direction. The bottom of the moving platform 421 is provided with a first pulley 4211 slidable relative to the first guide rail 712. In this way, the movement of the moving platform 421 in the first direction is guided by the cooperation of the first pulley 4211 and the first guide rail 712. Moreover, the contact area between the first pulley 4211 and the first guide rail 712 is small, which can reduce the friction between the first pulley 4211 and the first guide rail 712, and make the movement of the moving platform 421 relative to the fixed member 71 more smooth.

[0320] In some embodiments of the present application, by arranging the first guide rail 712 with a longer length and a larger mass on the fixed member 71, and arranging the first pulley 4211 with a smaller mass on the moving platform 421, the mass of the second moving assembly 420 can be reduced, which is beneficial to reduce the possibility of sagging of the second moving assembly 420.

[0321] In some embodiments, the first pulley 4211 is rotatably mounted on the bottom of the moving platform 421, such that the first pulley 4211 is in rolling contact with the first guide rail 712, so as to further reduce the friction between the first pulley 4211 and the first guide rail 712.

[0322] In some embodiments, the first pulley 4211 is arranged on both sides of the first guide rail 712, so as to improve the reliability and stability of the cooperation between the moving platform 421 and the fixed member 71.

[0323] In some embodiments, the first pulley 4211 can be a V-shaped pulley, and at least a portion of the first guide rail 712 is accommodated in the V-shaped groove of the first pulley 4211. Not only can the linear movement of the moving platform 421 be guided, but also the first pulley 4211 can serve as a carrier to support the moving platform 421 and the structure thereon, so as to make the movement of the second moving assembly 420 and the shovel disc 440 more stable.

[0324] Continuing to refer to Figure 11 and Figure 12 In some embodiments, a second guide structure is arranged between the moving platform 421 and the shovel disc 440, and the second guide structure is configured to guide the movement of the shovel disc 440 in the first direction, so as to improve the straightness of the movement of the shovel disc 440 in the first direction, and further improve the straightness of the movement of the sample box 10 in the first direction.

[0325] For example, the moving platform 421 is provided with a second guide rail 4212 extending in the first direction. The bottom of the shovel disc 440 is provided with a second sliding block slidably mounted on the second guide rail 4212, and the movement of the shovel disc 440 in the first direction is guided by the cooperation between the second sliding block and the second guide rail 4212.

[0326] For example, in combination with Figure 13 The moving platform 421 is provided with a second guide rail 4212 extending in the first direction. The bottom of the shovel disc 440 is provided with a second pulley 441 slidably arranged relative to the second guide rail 4212. In this way, the movement of the shovel disc 440 in the first direction is guided by the cooperation between the second pulley 441 and the second guide rail 4212, and the contact area between the second pulley 441 and the second guide rail 4212 is small, so as to reduce the friction between the second pulley 441 and the second guide rail 4212, and make the movement of the shovel disc 440 relative to the moving platform 421 more smooth.

[0327] In some embodiments of the present application, by arranging the second guide rail 4212 with a relatively long length and a relatively large mass on the moving platform 421, and arranging the second pulley 441 with a relatively small mass on the shovel disc 440, the mass driven by the second moving assembly 420 can be reduced, so as to reduce the possibility of the shovel disc 440 sagging.

[0328] In some embodiments, the second pulley 441 is rotatably mounted at the bottom of the shovel disc 440, such that the second pulley 441 is in rolling contact with the second guide rail 4212, so as to further reduce the friction between the second pulley 441 and the second guide rail 4212.

[0329] In some embodiments, the second pulley 441 is arranged on both sides of the second guide rail 4212, so as to improve the reliability and stability of the cooperation between the shovel disc 440 and the moving platform 421.

[0330] In some embodiments, the second pulley 441 can be a V-shaped pulley, and at least a part of the second guide rail 4212 is accommodated in the V-shaped groove of the second pulley 441. Not only can the linear movement of the shovel disc 440 be guided, but also the V-shaped pulley can play a supporting role to support the shovel disc 440 and the structure thereon, so that the movement of the second moving assembly 420 and the shovel disc 440 is more stable.

[0331] Continuing to refer to Figure 13 In some embodiments, the diameter of the second pulley 441 is smaller than the diameter of the first pulley 4211. In this way, the diameter of the second pulley 441 is smaller, which can reduce the mass of the second moving assembly 420, and can save the driving force for driving the second moving assembly 420 to move; the diameter of the first pulley 4211 is larger, which can increase the carrying capacity of the moving platform 421. In particular, when the shovel disc 440 extends relative to the moving platform 421, the larger first pulley 4211 can provide greater limiting force, which reduces the possibility of the shovel disc 440 sagging, and helps to ensure the reliability and stability of the movement of the sample box 10 driven by the shovel disc 440.

[0332] Continuing to refer to Figure 12 In some embodiments, the moving platform 421 includes a main body portion 4213, a connecting arm 4214, and an end arm 4215, which are connected in sequence along a first direction, i.e., the connecting arm 4214 is connected to the main body portion 4213 and the end arm 4215, respectively.

[0333] Exemplarily, the main body portion 4213, the connecting arm 4214, and the end arm 4215 are integrally formed as an integral piece, which facilitates improving the structural strength and stability of the moving platform 421.

[0334] In some embodiments, the first pulley 4211 is mounted at the bottom of the main body portion 4213, and the main body portion 4213 can be connected to the first flexible transmission member 412 through the first connecting member 450. The second guide rail 4212 is mounted to the main body portion 4213 and the connecting arm 4214.

[0335] One of the third transmission wheels 4221 is installed on the main body part 4213. The other third transmission wheel 4221 is installed on the end arm 4215, which can be bent relative to the connecting arm 4214 so that the end arm 4215 and the part of the main body part 4213 are spaced apart in the first direction, which can not only install the third transmission wheel 4221, but also reduce the volume of the end arm 4215, thereby facilitating the reduction of the overall mass of the mobile station 421.

[0336] The connecting arm 4214 extends in the first direction, and the size of the connecting arm 4214 in the second direction is smaller than the size of the main body part 4213 in the second direction, which facilitates the reduction of the mass of the mobile station 421, thereby facilitating the reduction of the driving force for driving the mobile station 421 to move in the first direction.

[0337] Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present application, and not to limit them; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: it can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for part or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application.

[0338] In order to facilitate explanation, the above description has been made in combination with specific embodiments. However, the above exemplary discussion is not intended to exhaust or limit the embodiments to the specific forms disclosed above. Various modifications and variations can be derived according to the above teachings. The selection and description of the above embodiments are to better explain the principles and practical applications, so that those skilled in the art can better use the embodiments and various different modified embodiments suitable for specific use considerations.

Claims

1. A cryogenic storage device, characterized by, The application relates to a box assembly (100) comprising: a storage cavity (101) configured to store sample boxes (10); a storage component (20) mounted in the storage cavity (101) and configured to accommodate the sample boxes (10); the storage component (20) comprises: a plurality of storage mechanisms (200) configured to accommodate the sample boxes (10); the storage mechanisms (200) are annular; the plurality of storage mechanisms (200) are coaxially arranged, and the plurality of storage mechanisms (200) are sequentially arranged in the radial direction and are arranged in the radial direction; a driving mechanism (300) configured to drive each storage mechanism (200) to rotate independently; a transfer component (70) arranged on the inner side of the innermost ring of the storage mechanisms (200); the transfer component (70) is configured to move vertically and in a first direction to transfer the sample boxes (10); wherein the vertical direction is perpendicular to the first direction. the transfer component (70) comprises:

2. The cryoablation device of claim 1, wherein, a fixing member (71) mounted on the inner side of the innermost ring of the storage mechanisms (200); a translation mechanism (400) comprising: a first moving assembly (410) configured to move the sample boxes (10) in the first direction; the first moving assembly (410) is mounted on the fixing member (71); a second moving assembly (420) connected to the first moving assembly (410) and configured to move the sample boxes (10) in the first direction; the second moving assembly (420) is provided with a shovel disc (440) to accommodate the sample boxes (10); a translation driving assembly (430) connected with the first moving assembly (410); the translation driving assembly (430) is configured to drive the first moving assembly (410) to move in the first direction, so that the first moving assembly (410) drives the second moving assembly (420) to move in the first direction. the first moving assembly (410) comprises:

3. The cryoablation device of claim 2, wherein, a first transmission wheel set (411) rotatably mounted on the fixing member (71) and connected with the translation driving assembly (430); a first flexible transmission member (412) wound around the first transmission wheel set (411); at least part of the first flexible transmission member (412) extends in the first direction; wherein the second moving assembly (420) is connected with the part of the first flexible transmission member (412) extending in the first direction. the second moving assembly (420) comprises:

4. The cryoablation device of claim 3, wherein, a moving table (421) slidably mounted on the fixing member (71); the moving table (421) is connected with the part of the first flexible transmission member (412) extending in the first direction; a second transmission wheel set (422) rotatably mounted on the moving table (421); a second flexible transmission member (423) wound around the second transmission wheel set (422); at least part of the second flexible transmission member (423) extends in the first direction; wherein the part of the second flexible transmission member (423) extending in the first direction is respectively connected with the fixing member (71) and the shovel disc (440). the translation mechanism (400) further comprises:

5. The cryo device of claim 4, wherein, a first connecting member (450) connecting the first flexible transmission member (412) and the moving table (421). ​ A second connecting member (460) is fixed to the fixed member (71), and the second connecting member (460) is connected with the second flexible transmission member (423); A third connecting member (470) connects the bucket (440) and the second flexible transmission member (423).

6. The cryogenic storage device of claim 4, wherein: The fixed member (71) is provided with a first guide rail (712) extending along the first direction; The bottom of the moving table (421) is provided with a first pulley (4211) slidable relative to the first guide rail (712); The top of the moving table (421) is provided with a second guide rail (4212) extending along the first direction; The bucket (440) is provided with a second pulley (441) slidable relative to the second guide rail (4212); The diameter of the second pulley (441) is smaller than that of the first pulley (4211).

7. The cryo device according to any of claims 3-6, characterized in that, The first transmission wheel set (411) comprises a driving wheel (4111) located above the fixed member (71); the driving wheel (4111) is provided with a shaft hole (4112); The translation driving assembly (430) comprises: A translation transmission shaft (432) extending in the vertical direction, and the translation transmission shaft (432) penetrates the shaft hole (4112) so that the driving wheel (4111) can slide along the translation transmission shaft (432); A translation driver (431) installed outside the storage cavity (101); the translation driver (431) is connected with the translation transmission shaft (432), and the translation driver (431) is configured to drive the driving wheel (4111) to rotate through the translation transmission shaft (432).

8. The cryo device according to any of claims 2-6, characterized in that, The transfer component (70) comprises a lifting mechanism (500); the lifting mechanism (500) comprises: A lifting transmission assembly (510) connected with the fixed member (71); A lifting driver (520) installed outside the storage cavity (101); the lifting driver (520) is connected with the lifting transmission assembly (510), and the lifting driver (520) drives the fixed member (71) to move in the vertical direction through the lifting transmission assembly (510).

9. The cryoablation device of claim 8, wherein, The lifting transmission assembly (510) comprises: A lead screw (511) extending in the vertical direction; the lead screw (511) is connected with the lifting driver (520); A nut (512) formed on the fixed member (71); the nut (512) is threadedly connected with the lead screw (511).

10. The cryo device according to any of claims 1-6, characterized in that, The storage mechanism (200) comprises: An upper turntable member (210) in a ring shape; A lower turntable member (220) in a ring shape; the lower turntable member (220) is arranged below the upper turntable member (210) in the vertical direction; A plurality of storage racks (230) fixed between the upper turntable member (210) and the lower turntable member (220), and the plurality of storage racks (230) are arranged in the circumferential direction of the upper turntable member (210).

11. The cryogenic storage device of claim 10, wherein, The storage component (20) further comprises a support disc (240); The support disc (240) is fixed in the storage cavity (101), and the support disc (240) is located below the lower turntable member (220); The support disc (240) is provided with a roller member (250), and the roller member (250) is configured to support the lower turntable member (220) and limit the rotation of the lower turntable member (220) around the center thereof.

12. The cryogenic storage device of any one of claims 1-6, wherein, The driving mechanism (300) is provided with a plurality of driving mechanisms (300), each of which is connected with one of the storage mechanisms (200) to drive the rotation of the storage mechanism (200).

13. The cryogenic storage device of claim 12, wherein, The driving mechanism (300) comprises: The rotary driver (310) is installed outside the storage cavity (101), and the rotary driver (310) is configured to drive the rotation of the storage mechanism (200); The rotary transmission assembly is connected with the output end of the rotary driver (310) and the storage mechanism (200) respectively to transmit the driving force of the rotary driver (310) to the storage mechanism (200).

14. A device for cryopreservation, characterized in that, It comprises: The box assembly (100) is configured to: The storage cavity (101) is configured to store the sample box (10); The buffer cavity (102) is configured to be selectively communicated with the buffer cavity (102); the temperature of the buffer cavity (102) is lower than that of the storage cavity (101); the buffer cavity (102) and the storage cavity (101) are arranged side by side along the first direction; The storage component (20) is installed in the storage cavity (101) and is configured to accommodate the sample box (10); The storage component (20) comprises: The first storage mechanism (200) is annular; the first storage mechanism (200) is configured to store the sample box (10); The second storage mechanism (200) is annular; the first storage mechanism (200) is configured to store the sample box (10); the second storage mechanism (200) is arranged outside the first storage mechanism (200), and the second storage mechanism (200) is coaxially arranged with the first storage mechanism (200); The driving mechanism (300) is configured to drive the independent rotation of the first storage mechanism (200) and the second storage mechanism (200); The transfer component (70) is arranged inside the first storage mechanism (200); the transfer component (70) is configured to vertically lift and move along the first direction to transfer the sample box (10) between the buffer cavity (102) and the storage mechanism (200); wherein, the vertical direction is perpendicular to the first direction.

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