Centrifugal machine device for nucleic acid extraction

Abstract

The utility model discloses a centrifugal machine device for nucleic acid extraction, which relates to the field of nucleic acid extraction, and comprises a device main body and a turntable, a circular truncated cone is mounted at the lower part in the device main body, a mounting groove is formed in the circular truncated cone, and a cooling component is arranged in the circular truncated cone; and the cooling assembly comprises a cooling cavity formed in the circular truncated cone and semiconductor chilling plates installed on the two sides of the device body, a heat conduction piece is installed on the inner wall of the cooling cavity, and a heat conduction piece extending into the installation groove is installed on the inner wall of the heat conduction piece. Through the arrangement of the cooling assembly, when the motor continuously works to generate a large amount of heat, the heat conducting fins can conduct heat so as to conduct the heat into the cooling cavity, and water in the cooling cavity can absorb heat, so that the purpose of cooling the motor is achieved, a large amount of heat is prevented from being accumulated around the motor, and the service life of the motor is prolonged. Therefore, the cooling effect on the motor is improved, and the service life of the motor is prolonged.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of nucleic acid extraction, in particular to a centrifuge device for nucleic acid extraction. BACKGROUND

[0002] In the process of nucleic acid extraction, a centrifuge is needed. The test tube containing nucleic acid is placed in the placement hole of the centrifuge, and then the centrifuge is started to centrifuge it.

[0003] According to the announcement number CN217663940U, a centrifuge device for nucleic acid extraction is disclosed. The centrifugal radius of the utility model can be freely adjusted, which can adapt to the centrifugation of different reagents. The utility model is firm and stable, and the centrifugation process is stable and safe, which can ensure the stable centrifugation of the reagent after nucleic acid extraction. The utility model is easy to operate and has high practicality.

[0004] According to the above-mentioned patent content, a motor and a turntable are provided to drive the turntable to rotate by the operation of the motor, and then drive the placement tube to rotate, and then drive the reagent tube to rotate, so as to achieve the purpose of centrifugation. However, the motor will generate heat after a long time of work. Since the centrifuge is in a sealed state during centrifugation, it is difficult to dissipate heat, which makes it difficult to dissipate heat for the motor, thereby accelerating the damage speed of the motor and reducing the service life of the motor. UTILITY MODEL CONTENT

[0005] Therefore, the utility model aims to provide a centrifuge device for nucleic acid extraction to solve the problem of poor heat dissipation effect of the motor.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical scheme: a centrifuge device for nucleic acid extraction, comprising a device main body and a turntable, a circular table is installed inside the lower part of the device main body, an installation groove is formed in the circular table, a cooling assembly is arranged in the circular table, and the cooling assembly comprises a cooling cavity formed in the inside of the circular table and a semiconductor refrigeration piece installed on both sides of the device main body, a heat conduction piece is installed on the inner wall of the cooling cavity, a heat conduction piece is installed on the inner wall of the heat conduction piece and extends into the installation groove, a plurality of disassembly and assembly assemblies are arranged on the top of the turntable, and the disassembly and assembly assemblies comprise a plurality of positioning grooves formed on the top of the turntable, a plurality of threaded rods screwed on the turntable and a plurality of grooves formed in the turntable, a positioning block is inserted into the inside of the positioning groove, a clamping groove is formed on one side of the positioning block, a spring is installed in the inside of the groove, one end of the spring is connected with a movable block, a connecting rod is installed on one side of the movable block, one end of the connecting rod is connected with a clamping block which extends into the clamping groove, and a pressing block is connected with the bottom end of the threaded rod through a bearing.

[0007] By adopting the above technical scheme, when the motor continuously works and generates a large amount of heat, the heat-conducting sheet and the heat-conducting sheet can conduct heat, so as to conduct the heat to the cooling cavity, and the water in the cooling cavity can absorb heat, so as to achieve the purpose of cooling the motor.

[0008] Further, the cooling assembly further comprises a protective cover mounted on the outer wall of the device body and a water inlet hole formed in the inner side of the circular table and the device body, and one side of the water inlet hole is clamped with a blocking plug.

[0009] By adopting the above technical scheme, when cold water needs to be added to the inside of the cooling cavity, the blocking plug can be taken out from the water inlet hole, and then water can be added to the cooling cavity through the water inlet hole.

[0010] Further, the blocking plug is matched with the water inlet hole, and the blocking plug is made of rubber material.

[0011] By adopting the above technical scheme, the blocking plug can block the water inlet hole, improving the sealing performance of the cooling cavity.

[0012] Further, the inside of the mounting groove is mounted with a motor, and the output end of the motor is connected with a rotating disc through a drive shaft.

[0013] By adopting the above technical scheme, when the nucleic acid extraction reagent needs to be centrifuged, the motor can be started, and the motor can drive the rotating disc to rotate, and then drive the placement tube to rotate, so as to centrifuge the nucleic acid extraction reagent.

[0014] Further, the top of the circular table is provided with a sliding groove, and a plurality of sliding blocks are arranged in the sliding groove, and the top of the sliding block is connected with the bottom of the rotating disc.

[0015] By adopting the above technical scheme, when the rotating disc rotates, the sliding block will slide in the sliding groove, thereby improving the stability of the rotating disc when rotating.

[0016] Further, the top of the positioning block is mounted with a placement tube, and the top end of the placement tube is rotatably connected with a safety plug.

[0017] By adopting the above technical scheme, the safety plug can block the top end of the placement tube to prevent the reagent from falling out.

[0018] Further, the placement tube is detachably connected with the rotating disc through the positioning block, and the top of the device body is rotatably connected with a cover plate.

[0019] By adopting the above technical scheme, the cover plate can be easily opened by the staff to put the nucleic acid extraction reagent into the placement tube.

[0020] Further, the positioning block is matched with the positioning groove, and the clamping block is matched with the clamping groove.

[0021] By adopting the technical scheme, the positioning block can be positioned when being inserted into the positioning groove, and the clamping block can be clamped and positioned when being inserted into the clamping groove.

[0022] Further, one side of the movable block and one side of the pressing block are both provided as inclined surfaces, and the one side of the movable block is in contact with the one side of the pressing block.

[0023] By adopting the technical scheme, when the pressing block moves downward, it pushes the movable block to move, the movable block drives the connecting rod to move, and the clamping block moves.

[0024] Further, a control panel is mounted on the outer surface of the device body, and the control panel is electrically connected with the motor and the semiconductor refrigeration sheet respectively.

[0025] By adopting the technical scheme, the motor and the semiconductor refrigeration sheet can be started or stopped through the control panel.

[0026] In summary, the utility model mainly has the following beneficial effects:

[0027] 1. The cooling assembly is arranged, when the motor continuously works to generate a large amount of heat, the heat-conducting sheet and the heat-conducting sheet can conduct heat, so as to conduct the heat to the cooling cavity, and the water in the cooling cavity can absorb heat, so as to cool the motor, prevent a large amount of heat from accumulating around the motor, and thus improve the cooling effect of the motor and prolong the service life of the motor.

[0028] 2. The semiconductor refrigeration sheet and the protective cover are arranged, after the water continuously absorbs heat, the water temperature rises, the semiconductor refrigeration sheet is started after the water temperature rises, the semiconductor refrigeration sheet can cool the water, so that the water in the cooling cavity can continuously absorb heat, and the protective cover can protect the semiconductor refrigeration sheet from being collided by external objects.

[0029] 3. The dismounting assembly is arranged, when it is necessary to replace the damaged or different-diameter placing pipe, the user can rotate the threaded rod, so that the threaded rod drives the pressing block to move upward, at this time, the pressing block no longer presses the movable block, the spring is stretched to push the movable block to reset and move, and then drive the clamping block to move, so that the clamping block moves out of the clamping groove and no longer clamps and positions the positioning block, at this time, the placing pipe can be taken out for replacement, when the placing pipe is installed, only need to insert the positioning block into the positioning groove and align the clamping block with the clamping groove, then rotate the threaded rod, so that the threaded rod drives the pressing block to move downward, the pressing block pushes the movable block to move in the direction of the positioning block and presses the spring, at the same time, drives the clamping block to be inserted into the clamping groove, and then clamps and positions the positioning block, so that the installation of the placing pipe is completed, and the placing pipe can be quickly dismounted and replaced through the mode, and the replacement efficiency is improved. BRIEF DESCRIPTION OF DRAWINGS

[0030] Figure 1 It is the whole three-dimensional structure schematic diagram of the utility model;

[0031] Figure 2 It is the whole positive section structure schematic diagram of the utility model;

[0032] Figure 3 It is the circular table structure schematic diagram of the utility model;

[0033] Figure 4 It is the placement cylinder structure schematic diagram of the utility model;

[0034] Figure 5 It is the positioning block side surface structure schematic diagram of the utility model;

[0035] Figure 6 It is the heat conduction ring structure schematic diagram of the utility model;

[0036] Figure 7 It is the Figure 2 The enlarged structure schematic diagram of A place in the utility model.

[0037] In the figure: 1, device main body;2, cover plate;3, placement pipe;4, safety plug;5, carousel;6, circular table;7, motor;8, control panel;9, cooling assembly;901, heat conduction ring;902, heat conduction sheet;903, cooling cavity;904, semiconductor refrigeration sheet;905, protective cover;906, water inlet hole;907, plugging plug;10, sliding block;11, sliding slot;12, dismounting assembly;1201, positioning block;1202, positioning groove;1203, clamping groove;1204, clamping block;1205, recess;1206, threaded rod;1207, movable block;1208, spring;1209, connecting rod;1210, pressing block;13, mounting groove. Specific implementation

[0038] The technical scheme in the utility model embodiment will be described clearly and completely below in conjunction with the drawings in the utility model embodiment. The embodiment described below with reference to the drawings is exemplary and is only used to explain the utility model, and cannot be understood as limiting the utility model.

[0039] The embodiment will be described below according to the overall structure of the utility model.

[0040] Embodiment one:

[0041] A kind of centrifuge device for nucleic acid extraction, such as Figures 1-7As shown, including device body 1 and turntable 5, the inside of device body 1 is mounted with a circular table 6, the circular table 6 is provided with a mounting groove 13, the circular table 6 is provided with a cooling assembly 9, the inside of the mounting groove 13 is provided with a motor 7, the output end of the motor 7 is connected with the turntable 5 through the driving shaft, when the nucleic acid extraction reagent needs to be centrifuged, the motor 7 can be started, the motor 7 can drive the turntable 5 to rotate, and then drive the placement tube 3 to rotate, so as to centrifuge the nucleic acid extraction reagent, the top of the positioning block 1201 is provided with the placement tube 3, the top end of the placement tube 3 is rotatably connected with the safety plug 4, the safety plug 4 can block the top end of the placement tube 3, avoiding the reagent tube from falling out.

[0042] Referring to Figures 2-5 , the cooling assembly 9 includes a cooling cavity 903 opened in the inside of the circular table 6 and a semiconductor refrigerating fin 904 mounted on both sides of the device body 1, the inner wall of the cooling cavity 903 is provided with a heat conducting ring 901, the inner wall of the heat conducting ring 901 is provided with a heat conducting fin 902 extending into the mounting groove 13, when the motor 7 continuously works and generates a large amount of heat, the heat conducting ring 901 and the heat conducting fin 902 can conduct heat, so as to conduct the heat to the inside of the cooling cavity 903, and the water in the cooling cavity 903 can absorb heat, so as to cool the motor 7, the outer surface of the device body 1 is provided with a control panel 8, the control panel 8 is electrically connected with the motor 7 and the semiconductor refrigerating fin 904, so as to start or stop the motor 7 and the semiconductor refrigerating fin 904 through the control panel 8, the top of the turntable 5 is provided with a plurality of disassembly assemblies 12.

[0043] Specifically, the disassembly assembly 12 includes a plurality of positioning grooves 1202 opened in the top of the turntable 5, a plurality of threaded rods 1206 screwed on the turntable 5 and a plurality of grooves 1205 opened in the turntable 5, the inside of the positioning groove 1202 is inserted with the positioning block 1201, one side of the positioning block 1201 is provided with a clamping groove 1203, the inside of the groove 1205 is provided with a spring 1208, one end of the spring 1208 is connected with a movable block 1207, one side of the movable block 1207 is provided with a connecting rod 1209, one end of the connecting rod 1209 is connected with a clamping block 1204 extending into the clamping groove 1203, the bottom end of the threaded rod 1206 is connected with a pressing block 1210 through a bearing, the placement tube 3 is detachably connected with the turntable 5 through the positioning block 1201.

[0044] Specifically, the top of the device body 1 is rotatably connected with the cover plate 2, which is convenient for the staff to open the cover plate 2, so as to put the nucleic acid extraction reagent into the placement tube 3. The positioning block 1201 is matched with the positioning groove 1202, and the clamping block 1204 is matched with the clamping groove 1203. When the positioning block 1201 is inserted into the positioning groove 1202, the placement tube 3 can be positioned. When the clamping block 1204 is clamped into the clamping groove 1203, the positioning block 1201 can be clamped and limited. The side of the movable block 1207 and the side of the pressing block 1210 are both inclinedly arranged. The side of the movable block 1207 is in contact with the side of the pressing block 1210. When the pressing block 1210 moves downward, it will push the movable block 1207 to move. The movable block 1207 will drive the connecting rod 1209 to move, and then drive the clamping block 1204 to move. The movable block 1207 is slidably connected with the groove 1205. The top end of the threaded rod 1206 is connected with a handle, so that the movable block 1207 can move in the groove 1205. The staff can rotate the threaded rod 1206 through the handle. The inner wall of the groove 1205 is provided with a limiting groove, and the limiting groove is provided with a limiting block. The side of the limiting block is connected with the pressing block 1210, so that the pressing block 1210 can drive the limiting block to slide in the limiting groove when the pressing block 1210 moves, thereby improving the stability of the pressing block 1210 when moving, and preventing the pressing block 1210 from rotating.

[0045] Example two:

[0046] On the basis of the above-mentioned example one, in order to improve the stability of the rotating disc 5 when rotating, the following structure is arranged.

[0047] Referring to Figure 2 and Figure 4 , the top of the circular table 6 is provided with a sliding groove 11. A plurality of sliding blocks 10 are arranged in the sliding groove 11. The top of the sliding block 10 is connected with the bottom of the rotating disc 5. The sliding groove 11 is annular. The sliding block 10 is slidably connected with the sliding groove 11. When the rotating disc 5 rotates, it will drive the sliding block 10 to slide in the sliding groove 11, thereby improving the stability of the rotating disc 5 when rotating.

[0048] Example three;

[0049] On the basis of the above-mentioned example one, in order to facilitate the protection of the semiconductor refrigeration piece 904 and avoid external objects colliding with the semiconductor refrigeration piece 904, the following structure is arranged.

[0050] Specific, cooling assembly 9 further comprises a protective cover 905 installed on the outer wall of the device body 1 and a water inlet hole 906 opened in the inner side of the circular table 6 and the device body 1, one side of the water inlet hole 906 is clamped with a blocking plug 907, when the cold water needs to be added to the cooling cavity 903, the blocking plug 907 can be removed from the water inlet hole 906, then the water can be added to the cooling cavity 903 through the water inlet hole 906, the blocking plug 907 is matched with the water inlet hole 906, the blocking plug 907 is made of rubber material, the blocking plug 907 can block the water inlet hole 906, improve the sealing of the cooling cavity 903, and the protective cover 905 can protect the semiconductor refrigeration piece 904 from being collided by external objects.

[0051] The working principle of the utility model is: first, the staff can first connect the power supply when using the device, then open the cover plate 2, then place the reagent tube in the placing pipe 3, and then insert the safety plug 4 into the top end of the placing pipe 3 to block the placing opening at the top end of the placing pipe 3, then cover the cover plate 2, and start the motor 7, the motor 7 can drive the rotating disc 5 to rotate, and then drive the placing pipe 3 to rotate, so as to centrifuge the nucleic acid extraction reagent, when the motor 7 continuously works and generates a large amount of heat, the heat conducting ring 901 and the heat conducting sheet 902 can conduct heat, so as to conduct heat to the cooling cavity 903, and the water in the cooling cavity 903 can absorb heat, so as to cool the motor 7, prevent a large amount of heat from accumulating around the motor 7, and improve the cooling effect of the motor 7;

[0052] Because the water continuously absorbs heat, the water temperature will rise, and when the water temperature rises, the semiconductor refrigeration piece 904 can be started, so that the semiconductor refrigeration piece 904 can cool the water, so that the water in the cooling cavity 903 can continuously absorb heat, and the protective cover 905 can protect the semiconductor refrigeration piece 904;

[0053] When the placement tube 3 needs to be replaced due to damage or use of a different diameter, the user can rotate the threaded rod 1206 so that the threaded rod 1206 drives the pressing block 1210 to move upwards, at which time the pressing block 1210 no longer extrudes the movable block 1207, the spring 1208 is stretched to push the movable block 1207 to reset and move, in turn driving the clamping block 1204 to move, so that the clamping block 1204 moves out of the inside of the clamping slot 1203 and no longer clamps and limits the positioning block 1201, at which time the placement tube 3 can be removed for replacement. When installing the placement tube 3, only need to insert the positioning block 1201 into the positioning slot 1202 and align the clamping block 1204 with the clamping slot 1203, then reverse rotate the threaded rod 1206 so that the threaded rod 1206 drives the pressing block 1210 to move downwards, the pressing block 1210 pushes the movable block 1207 to move in the direction of the positioning block 1201 and extrudes the spring 1208, at the same time drives the clamping block 1204 to clamp into the clamping slot 1203, in turn clamps and limits the positioning block 1201, so that the installation of the placement tube 3 is completed.

[0054] Although the embodiments of the utility model have been shown and described, the specific embodiments are only an explanation of the utility model, and are not a limitation of the utility model, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner, and the person skilled in the art can make modifications, replacements and variations of the embodiments without creative contribution after reading the specification without departing from the principles and purposes of the utility model, but as long as in the scope of the claims of the utility model, it is protected by the patent law.

Claims

1. A centrifuge device for nucleic acid extraction, comprising a device main body (1) and a turntable (5), characterized by: The inside of the device body (1) is provided with a circular table (6), the circular table (6) is provided with a mounting groove (13), the circular table (6) is provided with a cooling assembly (9), and the cooling assembly (9) comprises a cooling cavity (903) provided in the circular table (6) and a semiconductor refrigerating sheet (904) mounted on both sides of the device body (1), the inner wall of the cooling cavity (903) is provided with a heat conducting ring (901), the inner wall of the heat conducting ring (901) is provided with a heat conducting sheet (902) extending into the mounting groove (13), the top of the rotating disc (5) is provided with a plurality of dismounting assemblies (12), and the dismounting assembly (12) comprises a plurality of positioning grooves (1202) provided in the top of the rotating disc (5), a plurality of threaded rods (1206) screwed on the rotating disc (5) and a plurality of grooves (1205) provided in the rotating disc (5), the inside of the positioning groove (1202) is inserted with a positioning block (1201), one side of the positioning block (1201) is provided with a clamping groove (1203), the inside of the groove (1205) is provided with a spring (1208), one end of the spring (1208) is connected with a movable block (1207), one side of the movable block (1207) is provided with a connecting rod (1209), one end of the connecting rod (1209) is connected with a clamping block (1204) extending into the clamping groove (1203), and the bottom end of the threaded rod (1206) is connected with a pressing block (1210) through a bearing.

2. The centrifuge device for nucleic acid extraction according to claim 1, characterized by: The cooling assembly (9) further comprises a protective cover (905) mounted on the outer wall of the device body (1) and a water inlet hole (906) provided in the circular table (6) and one side of the device body (1).

3. The centrifuge apparatus for nucleic acid extraction according to claim 2, characterized by: The sealing plug (907) is matched with the water inlet hole (906), and the sealing plug (907) is made of rubber material.

4. The centrifuge apparatus for nucleic acid extraction according to claim 1, wherein: The inside of the mounting groove (13) is provided with a motor (7), and the output end of the motor (7) is connected with a rotating disc (5) through a driving shaft.

5. The centrifuge apparatus for nucleic acid extraction according to claim 4, wherein: The top of the circular table (6) is provided with a chute (11), and the inside of the chute (11) is provided with a plurality of sliding blocks (10), and the top of the sliding block (10) is connected with the bottom of the rotating disc (5).

6. The centrifuge apparatus for nucleic acid extraction according to claim 1, wherein: The top of the positioning block (1201) is provided with a placing pipe (3), and the top end of the placing pipe (3) is rotatably connected with a safety plug (4).

7. The centrifuge apparatus for nucleic acid extraction according to claim 6, wherein: The placing pipe (3) is detachably connected with the rotating disc (5) through the positioning block (1201), and the top of the device body (1) is rotatably connected with a cover plate (2).

8. The centrifuge apparatus for nucleic acid extraction according to claim 1, wherein: The positioning block (1201) is matched with the positioning groove (1202), and the clamping block (1204) is matched with the clamping groove (1203).

9. The centrifuge apparatus for nucleic acid extraction according to claim 1, wherein: One side of the movable block (1207) and one side of the pressing block (1210) are both provided with inclined surfaces, and one side of the movable block (1207) is in contact with one side of the pressing block (1210).

10. The centrifuge apparatus for nucleic acid extraction according to claim 4, characterized by: The outer surface of the device body (1) is provided with a control panel (8), and the control panel (8) is electrically connected with the motor (7) and the semiconductor refrigerating sheet (904).

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