Tablet press for producing sacubitril and valsartan sodium tablets

Abstract

The utility model discloses a tablet press for sacubitril valsartan sodium tablet production, and relates to the technical field of tablet presses, the tablet press comprises a box body and a mounting bin fixed at the top of the box body and communicated with the box body, two symmetrically arranged cranks are rotatably connected in the mounting bin, a movable rod located in the box body is rotatably connected between the two cranks, and the movable rod is located in the box body. An inclined rod is rotationally connected to the bottom of the movable rod, the two ends of the inclined rod are meshed with an adjusting rod and a stamping rod respectively, an upper die is fixed to the bottom of the stamping rod, a gear is meshed with the side, away from the inclined rod, of the stamping rod, and a fixed rack fixed in the box body is meshed with the other side of the gear; and the top of the adjusting rod is rotationally connected with a screw rod. The height of the adjusting rod in the vertical direction is adjusted by rotating the screw rod, the swing amplitude of the movable rod and the inclined rod is adjusted, the moving amplitude of the stamping rod and the upper die at the bottom of the stamping rod in the vertical direction is adjusted, and the tabletting thickness of sacubitril valsartan sodium tablets is adjusted.

Description

Technical Field

[0001] This utility model relates to the field of tablet press technology, specifically a tablet press for the production of sacubitril / valsartan sodium tablets. Background Technology

[0002] In pharmaceutical manufacturing, tablet compressors are one of the key pieces of equipment, especially in the production of tablet drugs such as sacubitril / valsartan sodium tablets. The performance of the tablet compressor directly affects the quality of the drug and production efficiency. As an important cardiovascular therapeutic drug, sacubitril / valsartan sodium tablets require strict control during the tablet compressing process. It is essential to ensure that each tablet has uniform thickness and consistent weight to meet the drug's efficacy and safety requirements.

[0003] These traditional tablet presses require different types of molds to adjust the tablet thickness, which makes it difficult to meet the high requirements of modern pharmaceutical industry for drug quality and production efficiency.

[0004] In view of the above, this application is hereby submitted. Utility Model Content

[0005] The purpose of this invention is to provide a tableting machine for the production of sacubitril / valsartan sodium tablets, so as to solve the problems mentioned in the background art.

[0006] To solve the above-mentioned technical problems, the present invention provides a tableting machine for producing sacubitril / valsartan sodium tablets, comprising: a housing, and an installation chamber fixed to the top of the housing and communicating with the housing. Two symmetrically arranged cranks are rotatably connected within the installation chamber. A movable rod located within the housing is rotatably connected between the two cranks. A diagonal rod is rotatably connected to the bottom of the movable rod. An adjusting rod and a punching rod are respectively engaged at both ends of the diagonal rod. An upper mold is fixed to the bottom of the punching rod. A gear is engaged on the side of the punching rod away from the diagonal rod, and a fixed rack fixed within the housing is engaged on the other side of the gear. A screw is rotatably connected to the top of the adjusting rod, and the screw is threaded to the top of the housing. By rotating the screw to adjust the vertical height of the adjusting rod, the swing amplitude of the movable rod and diagonal rod can be adjusted, as can the vertical movement amplitude of the punching rod and its bottom upper mold can be adjusted, thereby adjusting the tableting thickness of the sacubitril / valsartan sodium tablets.

[0007] Furthermore, the sidewalls of the inclined rod and the adjusting rod that are close to each other are fixed with protruding teeth, and the two protruding teeth mesh with each other with a clearance fit.

[0008] Furthermore, the sidewalls of the inclined rod and the stamping rod that are close to each other are fixed with two protruding teeth, which mesh with each other with a clearance fit. This ensures that the stamping rod moves smoothly in the vertical direction.

[0009] Furthermore, a slide block is slidably connected to the outer wall of the fixed rack, and a gear is rotatably connected to one end of the fixed rack. The slide block limits the gear, allowing the stamping rod to move vertically without jamming.

[0010] Furthermore, the top of the screw penetrates the housing and is threadedly connected to it. An adjusting handle is fixed to the top of the screw, and a triangular arrow is provided at the top of the adjusting handle. The vertical height of the adjusting rod is adjusted by the screw, and the arrow serves as an indicator for easy observation.

[0011] Furthermore, a positioning cylinder is fixed at the bottom of the box body, the upper mold is slidably connected inside the positioning cylinder, a conveyor belt is provided below the positioning cylinder, a lower mold is installed on the conveyor belt, and material is contained inside the lower mold.

[0012] Furthermore, a drive motor is fixed inside the installation chamber, and the output end of the drive motor is connected to a power shaft via a belt. The power shaft is fixed to the side wall of the crank.

[0013] Compared with the prior art, the beneficial effects of this utility model are:

[0014] 1. By rotating the screw to adjust the vertical height of the adjusting rod, the swing amplitude of the movable rod and the inclined rod can be precisely adjusted, ultimately allowing for adjustment of the vertical movement of the stamping rod and the die at its bottom. This design enables the tablet press to easily adapt to the production needs of sacubitril / valsartan sodium tablets of different thicknesses, greatly improving production flexibility and applicability.

[0015] 2. The meshing of the fixed rack and gear, along with the limiting action of the slide block on the gear, together constitute a reliable guiding and limiting mechanism for the movement of the punch rod. This not only ensures the precise vertical movement of the punch rod but also prevents potential jamming during movement, thus improving the reliability and stability of the tablet press.

[0016] 3. The adjustment handle and triangular arrow on the top of the screw allow the operator to easily adjust the height of the adjusting rod and visually observe the current height setting through the arrow. This design simplifies the operation process, improves work efficiency, and also facilitates real-time observation and adjustment by the operator. Attached Figure Description

[0017] Figure 1 A schematic diagram of the internal structure of the box in a tablet press used for the production of sacubitril / valsartan sodium tablets;

[0018] Figure 2 A schematic diagram of a tablet press used for the production of sacubitril / valsartan sodium tablets;

[0019] Figure 3This is a schematic diagram of the connection between the positioning cylinder and the upper mold in a tablet press used for the production of sacubitril / valsartan sodium tablets.

[0020] In the picture:

[0021] 10. Container body; 11. Installation compartment;

[0022] 20. Crank; 21. Sliding rod; 22. Diagonal rod;

[0023] 30. Adjusting rod; 31. Screw;

[0024] 40. Stamping rod; 41. Upper die; 42. Positioning cylinder; 43. Conveyor belt;

[0025] 50. Gear; 51. Fixed rack; 52. Slide. Detailed Implementation

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0027] Please see Figure 1-3 This utility model provides a technical solution: a tablet press for producing sacubitril / valsartan sodium tablets, including a housing 10 and an installation chamber 11 fixed to the top of the housing 10 and communicating with the housing 10. Two symmetrically arranged cranks 20 are rotatably connected inside the installation chamber 11. A drive motor is fixed inside the installation chamber 11. The output end of the drive motor is connected to a power shaft via a belt. The power shaft is fixed to the side wall of the cranks 20. A movable rod 21 located inside the housing 10 is rotatably connected between the two cranks 20. A diagonal rod 22 is rotatably connected to the bottom of the movable rod 21. An adjusting rod 30 and a punching rod 40 are respectively engaged at both ends of the diagonal rod 22. An upper mold 41 is fixed to the bottom of the punching rod 40. A gear 50 is engaged on the side of the punching rod 40 away from the diagonal rod 22. A fixed rack 51 fixed inside the housing 10 is engaged on the other side of the gear 50. A screw 31 is rotatably connected to the top of the adjusting rod 30. The screw 31 is threadedly connected to the top of the housing 10. By rotating the screw 31 to adjust the height of the adjusting rod 30 in the vertical direction, the swing amplitude of the movable rod 21 and the inclined rod 22 can be adjusted, thereby adjusting the vertical movement amplitude of the stamping rod 40 and the mold 41 at its bottom, and thus adjusting the tablet thickness of sacubitril / valsartan sodium tablets.

[0028] The tablet press used for producing sacubitril / valsartan sodium tablets has two teeth fixed to its adjacent sidewalls: the inclined rod 22 and the adjusting rod 30. Two teeth mesh with each other, with a clearance fit between them. Similarly, two teeth are fixed to the adjacent sidewalls of the inclined rod 22 and the punch rod 40. Two teeth mesh with each other, also with a clearance fit between them. This ensures smooth vertical movement of the punch rod 40. A slide block 52 is slidably connected to the outer wall of the fixed rack 51, and a gear 50 is rotatably connected to one end of the fixed rack 51. The slide block 52 limits the movement of the gear 50, preventing the punch rod 40 from jamming during vertical movement.

[0029] The tablet press for producing sacubitril / valsartan sodium tablets has a screw 31 that passes through and is threadedly connected to the housing 10. An adjusting handle is fixed to the top of the screw 31, and a triangular arrow is positioned on the top of the handle. The screw 31 is used to adjust the vertical position of the adjusting rod 30, and the arrow serves as an indicator for easy observation. A positioning cylinder 42 is fixed to the bottom of the housing 10, and an upper mold 41 is slidably connected within the positioning cylinder 42. A conveyor belt 43 is located below the positioning cylinder 42, and a lower mold is mounted on the conveyor belt 43, containing the material.

[0030] Working principle:

[0031] Rotate the adjusting handle located at the top of the screw 31, using the triangular arrow as an indicator, to adjust the vertical position of the screw 31 at the top of the housing 10.

[0032] The output of the drive motor drives the power shaft to rotate via a belt. The power shaft is fixed to the side wall of the crank 20, thereby driving the crank 20 to rotate. The rotation of the crank 20, through the linkage of the movable rod 21 and the inclined rod 22, causes the stamping rod 40 to reciprocate in the vertical direction.

[0033] During this process: due to the meshing of the first tooth of the adjusting rod 30 and the inclined rod 22, the inclined rod 22 will swing accordingly. The swing of the inclined rod 22 changes the vertical movement amplitude of the stamping rod 40 through the interaction of the second tooth and the stamping rod 40, thereby adjusting the stamping depth of the upper die 41, and thus realizing the adjustment of the tablet thickness of sacubitril / valsartan sodium tablets.

[0034] When the stamping rod 40 descends, the upper die 41 contacts the lower die on the conveyor belt 43, stamping the material. The gear 50 slides on the fixed rack 51 and is simultaneously limited by the slide block 52, ensuring that the stamping rod 40 moves smoothly and does not jam. After tableting is completed, the stamping rod 40 rises, the upper die 41 leaves the lower die, and the conveyor belt 43 transports the pressed tablets to the next process.

Claims

1. A tablet press for producing sacubitril / valsartan sodium tablets, comprising a housing (10) and an installation chamber (11) fixed to the top of the housing (10) and communicating with the housing (10), characterized in that: The installation chamber (11) is rotatably connected to two symmetrically arranged cranks (20). A movable rod (21) located inside the housing (10) is rotatably connected between the two cranks (20). A diagonal rod (22) is rotatably connected to the bottom of the movable rod (21). An adjusting rod (30) and a stamping rod (40) are respectively engaged at both ends of the diagonal rod (22). An upper mold (41) is fixed at the bottom of the stamping rod (40). A gear (50) is engaged on the side of the stamping rod (40) away from the diagonal rod (22). A fixed rack (51) fixed inside the housing (10) is engaged on the other side of the gear (50). A screw (31) is rotatably connected to the top of the adjusting rod (30). The screw (31) is threadedly connected to the top of the housing (10).

2. The tableting machine for producing sacubitril / valsartan sodium tablets as described in claim 1, characterized in that: The inclined rod (22) and the adjusting rod (30) are both fixed with protruding teeth on their sidewalls that are close to each other. The two protruding teeth mesh with each other and are in clearance fit.

3. The tableting machine for producing sacubitril / valsartan sodium tablets as described in claim 1, characterized in that: The inclined rod (22) and the stamping rod (40) are both fixed with two protruding teeth on their sidewalls that are close to each other. The two protruding teeth mesh with each other and are in clearance fit.

4. The tableting machine for producing sacubitril / valsartan sodium tablets as described in claim 1, characterized in that: The outer wall of the fixed rack (51) is slidably connected to a slide block (52), and the gear (50) is rotatably connected to one end of the fixed rack (51).

5. The tableting machine for producing sacubitril / valsartan sodium tablets as described in claim 1, characterized in that: The top of the screw (31) passes through the housing (10) and is threadedly connected to it. An adjustment handle is fixed to the top of the screw (31), and a triangular arrow is provided on the top of the adjustment handle.

6. The tableting machine for producing sacubitril / valsartan sodium tablets as described in claim 1, characterized in that: The bottom of the box (10) is fixed with a positioning cylinder (42), the upper mold (41) is slidably connected to the positioning cylinder (42), a conveyor belt (43) is provided below the positioning cylinder (42), a lower mold is installed on the conveyor belt (43), and the lower mold contains materials.

7. The tableting machine for producing sacubitril / valsartan sodium tablets as described in claim 1, characterized in that: The installation chamber (11) is equipped with a drive motor. The output end of the drive motor is connected to a power shaft via a belt. The power shaft is fixed to the side wall of the crank (20).

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