Stem cell storage equipment with high sealing performance

Abstract

The utility model relates to the field of storage equipment, in particular to high-sealing stem cell storage equipment which comprises a storage barrel, a storage mechanism, a moving rod, a first annular sealing pipe and a vertical lifting mechanism. Sliding blocks are arranged at the bottoms of the moving rods, fixing frames are slidably arranged on the outer sides of the sliding blocks, the bottoms of the fixing frames are fixedly connected with the bottoms of the inner sides of the storage barrels, and connecting rings are arranged at the tops of the moving rods. A second annular sealing pipe is slidably arranged on the outer side of the first annular sealing pipe, and the top of the first annular sealing pipe is connected with the top of the inner side of the storage barrel; the vertical lifting mechanism is arranged on the inner side of the storage barrel. Through the arrangement of the vertical lifting mechanism, the holding rod is rotated to drive the moving rod to ascend, and the moving rod drives the storage table to vertically ascend and descend, so that the whole equipment does not need to be opened, the sealing state of the equipment can be always kept, and the heat preservation effect is enhanced.

Description

Technical Field

[0001] This utility model relates to the field of storage devices, and more particularly to a highly airtight stem cell storage device. Background Technology

[0002] Stem cells possess the potential for self-renewal and differentiation into various cell types, thus holding broad application prospects in regenerative medicine and disease treatment. With the development of biotechnology and increased public awareness of health, the stem cell storage industry has experienced rapid growth globally. Stem cell storage services typically involve the collection, separation, and cryopreservation of stem cell-rich tissues such as umbilical cord blood and placenta from newborns for future use in treating certain diseases.

[0003] Chinese Patent No. CN221776530U discloses a design including an inner tank with an outer shell. A vacuum cavity exists between the inner and outer tanks. A sealing cap is threaded onto the top of the inner tank, and an annular airbag is installed on the inner top of the sealing cap, positioned directly above the side wall of the inner tank. A fixing sleeve is fixed to the bottom of the sealing cap. This invention improves the sealing effect during use by installing an upper sealing plate at the bottom of the sealing cap and a hollow sealing ring on the outer side of the upper sealing plate. The hollow sealing ring is connected to the annular airbag on the inner top of the sealing cap via a conduit. During the installation of the sealing cap, gas from the annular airbag is injected into the hollow sealing ring, causing it to expand and adhere to the inside of the inner tank, forming a double-layer seal. Furthermore, a lower sealing plate inside the inner tank covers the top of the liquid nitrogen, forming a triple-layer seal, thus enhancing the sealing effect during use.

[0004] However, the aforementioned publicly available solutions have the following shortcomings: existing stem cell storage devices require the device to be opened during storage and retrieval, at which time liquid nitrogen is easily evaporated, resulting in a waste of resources. At the same time, the overall sealing of the device is not good enough, and the heat preservation effect on stem cells is poor, which can easily affect the activity of stem cells. Utility Model Content

[0005] The purpose of this invention is to address the problem in the prior art where the equipment has poor sealing and liquid nitrogen easily evaporates when the equipment is opened, and to propose a highly airtight stem cell storage device.

[0006] The technical solution of this utility model is as follows: a highly airtight stem cell storage device, including a storage cylinder; and further comprising:

[0007] The storage mechanism is slidably mounted on top of the storage tank and is used to store stem cells by filling it with liquid nitrogen.

[0008] The movable rod has a slider at its bottom, and a fixed frame is slidably mounted on the outside of the slider. The bottom of the fixed frame is fixedly connected to the bottom of the inner side of the storage cylinder. A connecting ring is mounted on the top of the movable rod, and the top of the connecting ring is fixedly connected to the bottom of the storage mechanism. The movable rod moves within the fixed frame via the slider, and when it reaches the top, it causes the storage mechanism to extend out of the storage cylinder.

[0009] An annular sealing tube 1 is provided, and an annular sealing tube 2 is slidably arranged on the outside of the annular sealing tube 1. The top of the annular sealing tube 1 is connected to the top of the inner side of the storage cylinder, and the annular sealing tube 1 is located on the outside of the storage mechanism. The bottom of the annular sealing tube 2 is connected to the bottom of the storage mechanism. Both the annular sealing tube 1 and the annular sealing tube 2 are made of heat-conducting materials.

[0010] And a vertical lifting mechanism, which is located inside the storage tank and is used to control the lifting of the storage mechanism inside the storage tank by rotating it from the outside.

[0011] Preferably, it also includes a capping assembly, which includes a sliding sealing plate, a fixing member, and a fixing block.

[0012] Fixed block three is set on the top of the storage cylinder, sliding sealing plate is slidably set on fixed block, fixing member is set on the top of sliding sealing plate, insert rod is slidably set on the inner side of fixing member, and spring three is set on the outer side of insert rod.

[0013] Preferably, the storage mechanism includes a storage platform, a fixed block, a rotating door, and a pull ring;

[0014] The storage platform is slidably mounted on the top of the connecting ring. The outer side of the storage platform is connected to the inner side of the annular sealing tube one. The second fixing block is mounted on the top of the storage platform. The rotating door is mounted on the inner side of the second fixing block. The pull ring is mounted on the top of the rotating door. The bottom of the annular sealing tube one is equipped with an installation block. The bottom of the installation block is equipped with a second spring. The inner side of the second spring is equipped with a telescopic tube.

[0015] Preferably, the vertical lifting mechanism includes a lifting component and a locking component;

[0016] The lifting assembly is mounted on the storage cylinder and is used to drive the storage mechanism to move up and down;

[0017] The locking component is located on the outside of the storage cylinder and is used to lock the lifting component in place after it has been moved to the appropriate position.

[0018] Preferably, the lifting assembly includes a rotating shaft, a rotating rod, a handle, and a circular gear.

[0019] A rotating shaft is rotatably mounted on the storage cylinder. A rotating rod is located at the end of the rotating shaft. A handle is located at the end of the rotating rod away from the rotating shaft. A spur gear is located on the outside of the rotating shaft. A spur gear is located at the bottom of the spur gear. A rotating shaft is located at the center of the spur gear. A spur gear is located at the end of the rotating shaft away from the spur gear. A connecting piece is rotatably mounted on the outside of the rotating shaft. A rack meshes with the side of the spur gear.

[0020] Preferably, the locking assembly includes a rotating wheel, a fixed shaft, a limiting rod, and a spring.

[0021] The rotating wheel is located on the outside of the rotating shaft, the fixed shaft is located on the outside of the storage cylinder, the limiting rod is rotatably located on the outside of the fixed shaft, the spring is located at the end of the limiting rod, there are two springs symmetrically arranged about the limiting rod, and the end of the spring away from the limiting rod is provided with a fixing block.

[0022] Compared with the prior art, the present invention has the following beneficial technical effects:

[0023] 1. By using a vertical lifting mechanism, rotating the handle drives the moving rod upward, which in turn moves the storage platform vertically. This eliminates the need to open the entire device; simply moving the storage platform to the top of the storage cylinder allows for the removal and use of the preserved stem cells. This maintains the device's airtight seal, effectively isolating it from external air, microorganisms, and other potential contaminants. It also prevents fluctuations in external temperature and humidity from negatively impacting the preservation of stem cells.

[0024] 2. By designing the storage mechanism and sealing assembly, the liquid nitrogen inside the storage platform and storage cylinder is separated, while ensuring that the temperature of the liquid nitrogen can be transferred to the stem cells inside the storage platform. This prevents the liquid nitrogen from adhering to the storage platform and evaporating when the storage platform is moved to the outside, thus avoiding waste. At the same time, it does not affect the heat preservation effect of the stem cells. The sliding sealing plate can slide on the storage cylinder to seal the top of the storage platform. Together with the piston on the rotating door, it provides a double seal for the stem cells in the empty slot of the storage platform, further enhancing the sealing effect and thus strengthening the heat preservation effect of the stem cells and maintaining their activity. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the structure of one embodiment of the present utility model;

[0026] Figure 2 for Figure 1 Internal structure diagram;

[0027] Figure 3 This is a schematic diagram of a vertical lifting structure;

[0028] Figure 4 for Figure 3 Enlarged diagram of A in the middle;

[0029] Figure 5 This is a schematic diagram of the storage mechanism;

[0030] Figure 6 This is a schematic diagram of the internal structure of the storage mechanism;

[0031] Figure 7 This is a schematic diagram of the capping assembly.

[0032] Reference numerals in the attached drawings: 1. Storage cylinder; 201. Sliding sealing plate; 202. Fixing component; 203. Fixing block three; 204. Insert rod; 205. Spring three; 301. Handle rod; 302. Rotating rod; 303. Rotating shaft one; 304. Fixing block one; 305. Spring one; 306. Fixing shaft; 307. Limiting rod; 308. Rotating wheel; 309. Circular gear one; 310. Circular gear two; 311. Rotating shaft two; 312. Circular gear three; 313. Rack; 314. Moving rod; 315. Sliding block; 316. Fixing frame; 317. Connecting ring; 318. Connecting component; 401. Storage platform; 402. Fixing block two; 403. Rotating door; 404. Pull ring; 405. Annular sealing tube one; 406. Annular sealing tube two; 407. Mounting block; 408. Spring two; 409. Telescopic tube. Detailed Implementation

[0033] Example 1

[0034] like Figures 1-7 As shown, the present invention proposes a highly airtight stem cell storage device, comprising a storage cylinder 1, a storage mechanism, a moving rod 314, an annular sealing tube 405, and a vertical lifting mechanism. The storage cylinder 1 is filled with liquid nitrogen.

[0035] The storage mechanism is slidably mounted on top of the storage tank and is used to store stem cells by filling it with liquid nitrogen.

[0036] The bottom of the moving rod 314 is provided with a slider 315, and a fixed frame 316 is slidably provided on the outside of the slider 315. The bottom of the fixed frame 316 is fixedly connected to the bottom of the inner side of the storage cylinder 1. The top of the moving rod 314 is provided with a connecting ring 317, and the top of the connecting ring 317 is fixedly connected to the bottom of the storage mechanism. The moving rod 314 moves within the fixed frame 316 through the slider 315, and when it moves to the top, it drives the storage mechanism to extend out of the storage cylinder 1.

[0037] An annular sealing tube 406 is slidably disposed on the outside of the annular sealing tube 405. The top of the annular sealing tube 405 is connected to the top of the inner side of the storage cylinder 1, and the annular sealing tube 405 is located on the outside of the storage mechanism. The bottom of the annular sealing tube 406 is connected to the bottom of the storage mechanism. Both the annular sealing tube 405 and the annular sealing tube 406 are thermally conductive materials. The annular sealing tube 406 can move with the storage platform 401, so the liquid nitrogen in the storage cylinder 1 can always be separated from the storage platform 401, avoiding the liquid nitrogen from adhering to the storage cylinder 1 and evaporating after being transported to the outside.

[0038] The vertical lifting mechanism is located inside the storage tank and is used to control the lifting of the storage mechanism inside the storage tank by rotating it from the outside.

[0039] The sealing assembly includes a sliding sealing plate 201, a fixing member 202, and a fixing block 203. The fixing block 203 is located on the top of the storage cylinder 1. The sliding sealing plate 201 is slidably mounted on the fixing block. The fixing member 202 is located on the top of the sliding sealing plate 201. An insert rod 204 is slidably mounted on the inner side of the fixing member 202. A spring 205 is mounted on the outer side of the insert rod 204. Holding the insert rod 204 can cause the sliding sealing plate 201 to slide on the fixing block 203, thereby sealing or opening the top of the storage cylinder 1. When sealing, the insert rod 204 can be pulled up, at which point the spring 205 is compressed. Then, the two sliding sealing plates 201 are pressed together. Then, the insert rod 204 is released. At this time, the insert rod 204 is inserted into the fixing block 203 under the action of the spring 205, thereby sealing the top of the storage cylinder 1 with the two sliding sealing plates 201.

[0040] The storage mechanism includes a storage platform 401, a second fixing block 402, a rotating door 403, and a pull ring 404. The storage platform 401 is slidably mounted on the top of the connecting ring 317. The outer side of the storage platform 401 is connected to the inner side of the annular sealing tube 405. The second fixing block 402 is located on the top of the storage platform 401. The rotating door 403 is located on the inner side of the second fixing block 402. The pull ring 404 is located on the top of the rotating door 403. Multiple rotating doors 403 are provided, and a rubber piston is provided at the bottom of each rotating door 403. Each rotating door 403 has a slot below it for placing a stem cell storage container. The rubber piston improves the sealing effect of the rotating door 403. The bottom of the annular sealing tube 405 is provided with... An installation block 407 is provided, and a second spring 408 is provided at the bottom of the installation block 407. A telescopic tube 409 is provided on the inner side of the second spring 408. The end of the telescopic tube 409 away from the first annular sealing tube 405 is connected to the inner side of the second annular sealing tube 406. When the connecting ring 317 drives the storage platform 401 to rise, the storage platform 401 drives the second annular sealing tube 406 to rise. At this time, the second spring 408 and the telescopic tube 409 are compressed. When the storage platform 401 descends, the second annular sealing tube 406 descends together, thereby stretching the second spring 408 and the telescopic tube 409. This ensures that the first annular sealing tube 405 and the second annular sealing tube 406 always block the outer wall of the storage platform 401.

[0041] Example 2

[0042] like Figures 3-4 As shown, this utility model proposes a highly sealed stem cell storage device. Compared with Embodiment 1, this embodiment details the structure of the vertical lifting mechanism.

[0043] The vertical lifting mechanism includes a lifting assembly and a locking assembly. The lifting assembly is mounted on the storage cylinder 1 and is used to drive the storage mechanism to move up and down. The locking assembly is located on the outside of the storage cylinder 1 and is used to lock the lifting assembly in place after it has moved to the appropriate position. The lifting assembly includes a rotating shaft 303, a rotating rod 302, a handle 301, and a spur gear 309. The rotating shaft 303 is rotatably mounted on the storage cylinder 1. The rotating rod 302 is located at the end of the rotating shaft 303. The handle 301 is located at the end of the rotating rod 302 away from the rotating shaft 303. The spur gear 309 is located on the outside of the rotating shaft 303. A second spur gear 310 is located at the bottom of the first spur gear 309. A second rotating shaft 311 is located at the axis of the second spur gear 310. A third spur gear 312 is located at the end of the second rotating shaft 311 away from the second spur gear 310. A connecting piece 318 is provided for side rotation. A rack 313 meshes with the side of the third spur gear 312. Rotating the handle 301 drives the rotating rod 302 to rotate. The rotating rod 302 drives the first rotating shaft 303 to rotate. The first rotating shaft 303 drives the second spur gear 310 to rotate through the first spur gear 309. The second spur gear 310 drives the third spur gear 312 to rotate through the second rotating shaft 311. The third spur gear 312 drives the rack 313 to move. The rack 313 drives the moving rod 314 to move within the fixed frame 316 through the slider 315. The moving rod 314 drives the storage platform 401 to rise through the connecting ring 317. The locking assembly includes a rotating wheel 308, a fixed shaft 306, a limiting rod 307, and a spring 305. The rotating wheel 308 is located outside the rotating shaft 303, the fixed shaft 306 is located outside the storage cylinder 1, the limiting rod 307 is rotatably located outside the fixed shaft 306, and the spring 305 is located at the end of the limiting rod 307. There are two springs 305 symmetrically arranged about the limiting rod 307. A fixing block 304 is provided at the end of the spring 305 away from the limiting rod 307. When the moving rod 314 moves to any position, the limiting rod 307 is locked onto the rotating wheel 308, which restricts the position of the rotating wheel 308 and thus fixes the position of the moving rod 314.

[0044] In summary, when using this utility model, to remove stem cells, first pull up the insertion rod 204 to detach it from the fixing block 203, move the sliding sealing plate 201 to open the top of the storage cylinder 1, then press the limiting rod 307 to detach it from the rotating wheel 308, grasp the grip rod 301 and rotate it. The grip rod 301 drives the rotating rod 302 to rotate, the rotating rod 302 drives the rotating shaft 303 to rotate, the rotating shaft 303 drives the rotating gear 310 to rotate through the rotating gear 309, the rotating gear 310 drives the rotating gear 312 to rotate through the rotating shaft 311, the rotating gear 312 drives the rack 313 to move, the rack 313 drives the moving rod 314 to move within the fixing frame 316 through the slider 315, the moving rod 314 drives the storage platform 401 to rise through the connecting ring 317 until it extends out of the storage cylinder 1, at which point the limiting rod 307 is released. The limiting rod 307 returns to its original position under the elastic action of the spring 305, locking the rotating wheel 308. During the process of the storage platform 401 rising, the storage platform 401 drives the second annular sealing tube 406 to rise, thereby sliding inside the first annular sealing tube 405. At this time, the second spring 408 and the telescopic tube 409 are compressed. When the stem cells are in the preservation state, the storage platform 401 is completely located inside the storage cylinder 1. The first annular sealing tube 405 and the second annular sealing tube 406 block the outside of the storage platform 401 from the liquid nitrogen grid. The liquid nitrogen transfers temperature through the first annular sealing tube 405 and the second annular sealing tube 406 to keep the stem cells in the storage platform 401 warm. The two sliding sealing plates 201 move to the position where they fit together, and then the position is fixed by the insertion rod 204, achieving the double sealing effect of the rotating door 403 and the sliding sealing plate 201.

[0045] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited thereto. Various changes can be made within the scope of knowledge possessed by those skilled in the art without departing from the spirit of the present invention.

Claims

1. A highly airtight stem cell storage device, comprising a storage cylinder (1); characterized in that, Also includes: The storage mechanism is slidably mounted on top of the storage tank and is used to store stem cells by filling it with liquid nitrogen. A movable rod (314) is provided with a slider (315) at the bottom of the movable rod (314). A fixed frame (316) is slidably provided on the outside of the slider (315). The bottom of the fixed frame (316) is fixedly connected to the bottom of the inner side of the storage cylinder (1). A connecting ring (317) is provided on the top of the movable rod (314). The top of the connecting ring (317) is fixedly connected to the bottom of the storage mechanism. The movable rod (314) moves within the fixed frame (316) through the slider (315). When it moves to the top, it drives the storage mechanism to extend out of the storage cylinder (1). An annular sealing tube 1 (405) is provided, and an annular sealing tube 2 (406) is slidably provided on the outside of the annular sealing tube 1 (405). The top of the annular sealing tube 1 (405) is connected to the top of the inner side of the storage cylinder (1), and the annular sealing tube 1 (405) is located on the outside of the storage mechanism. The bottom of the annular sealing tube 2 (406) is connected to the bottom of the storage mechanism. Both the annular sealing tube 1 (405) and the annular sealing tube 2 (406) are made of heat-conducting materials. And a vertical lifting mechanism, which is located inside the storage tank and is used to control the lifting of the storage mechanism inside the storage tank by rotating it from the outside.

2. The highly sealed stem cell storage device according to claim 1, characterized in that, It also includes a capping assembly, which includes a sliding sealing plate (201), a fastener (202), and a fixing block three (203); Fixed block three (203) is set on the top of storage cylinder (1), sliding sealing plate (201) is slidably set on fixed block, fixing member (202) is set on the top of sliding sealing plate (201), insert rod (204) is slidably set on the inner side of fixing member (202), and spring three (205) is set on the outer side of insert rod (204).

3. The highly sealed stem cell storage device according to claim 1, characterized in that, The storage mechanism includes a storage platform (401), a fixed block (402), a rotating door (403), and a pull ring (404); The storage platform (401) is slidably mounted on the top of the connecting ring (317). The outer side of the storage platform (401) is connected to the inner side of the annular sealing tube (405). The second fixing block (402) is mounted on the top of the storage platform (401). The rotating door (403) is mounted on the inner side of the second fixing block (402). The pull ring (404) is mounted on the top of the rotating door (403). The bottom of the annular sealing tube (405) is provided with an installation block (407). The bottom of the installation block (407) is provided with a second spring (408). The inner side of the second spring (408) is provided with a telescopic tube (409).

4. The highly airtight stem cell storage device according to claim 1, characterized in that, The vertical lifting mechanism includes a lifting component and a locking component; The lifting assembly is mounted on the storage cylinder (1) and is used to drive the storage mechanism to move up and down; The locking component is located on the outside of the storage cylinder (1) and is used to lock the position of the lifting component after it has been moved to the appropriate position.

5. The highly sealed stem cell storage device according to claim 4, characterized in that, The lifting assembly includes a pivot (303), a rotating rod (302), a handle (301), and a spur gear (309); A rotating shaft (303) is rotatably mounted on a storage cylinder (1). A rotating rod (302) is mounted at the end of the rotating shaft (303). A handle (301) is mounted at the end of the rotating rod (302) away from the rotating shaft (303). A spur gear (309) is mounted on the outside of the rotating shaft (303). A spur gear (310) is mounted at the bottom of the spur gear (309). A rotating shaft (311) is mounted at the center of the spur gear (310). A spur gear (312) is mounted at the end of the rotating shaft (311) away from the spur gear (310). A connecting piece (318) is rotatably mounted on the outside of the rotating shaft (311). A rack (313) meshes with the side of the spur gear (312).

6. The highly sealed stem cell storage device according to claim 5, characterized in that, The locking assembly includes a rotating wheel (308), a fixed shaft (306), a limit rod (307), and a spring (305); The rotating wheel (308) is located on the outside of the rotating shaft (303), the fixed shaft (306) is located on the outside of the storage cylinder (1), the limiting rod (307) is rotatably located on the outside of the fixed shaft (306), the spring (305) is located at the end of the limiting rod (307), there are two springs (305) symmetrically arranged about the limiting rod (307), and the end of the spring (305) away from the limiting rod (307) is provided with a fixing block (304).

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