Brain tissue slicing tool suitable for brain groove
By designing a brain tissue slicing tool suitable for the cerebral sulcus, and using guide grooves and guide blocks to stabilize the blade position, the problems of inaccurate slicing and low efficiency in the existing technology are solved, and efficient and accurate brain tissue slicing is achieved.
Patent Information
- Application Number
- CN202422896080.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-27
- Publication Date
- 2025-11-14
- Estimated Expiration
- 2034-11-27
AI Technical Summary
In existing technologies, when using double-edged blades to cut rat brains, brain tissue is prone to adhesion and displacement, resulting in inaccurate slicing and low efficiency. Furthermore, manual operation can easily damage tissue activity.
A brain tissue slicing tool was designed, comprising a main frame and an adjustable blade assembly. The blade is stably positioned using guide grooves and guide blocks, and a single-slice forming is achieved by adjusting the blade spacing. An anti-slip layer and a scale are used to improve operational accuracy.
This improved the accuracy and efficiency of brain tissue slicing, reduced tissue damage, and ensured the integrity and consistency of the slices.
Smart Images

Figure CN223545353U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of medical experimental instruments, specifically to a brain tissue slicing tool suitable for the cerebral groove. Background Technology
[0002] Brain molds, also called brain grooves, are essential equipment for obtaining slides of mouse brains. Currently, when using brain grooves to slice brain tissue, double-edged blades are used. However, using double-edged blades to cut mouse brains slice by slice has several drawbacks: First, because ordinary double-edged blades are made of stainless steel, they have tissue adhesion properties. After each slice, the brain tissue sticks to the blade and is carried away by the blade, making it impossible to make a second slice. Second, even if the tissue is not carried away by the first slice, it is still easy for it to shift or slip due to the force of the first slice, resulting in inaccurate brain slice extraction. Third, single-slice cutting is not conducive to maintaining the viability of fresh brain tissue and is inefficient. Fourth, single-slice cutting, due to manual operation, has a certain angle, which can easily damage the brain tissue and cause the slices to break. Utility Model Content
[0003] In view of the shortcomings of the existing technology, the purpose of this utility model is to provide a brain tissue slicing tool suitable for the cerebral groove.
[0004] To achieve the above objectives, the present invention provides the following technical solution:
[0005] A brain tissue slicing tool suitable for the cerebral sulcus, comprising:
[0006] The main frame includes a horizontal section and two vertical sections with two vertical horizontal sections, and a slicing space that can accommodate a cutter is formed between the two vertical sections. The two vertical sections are provided with guide grooves along the length of the vertical sections. The other end of the vertical section is provided with a detachable closed section. The closed section, the horizontal section and the two vertical sections form a rectangular frame. The two sides of the rectangular frame are provided with operating parts for hand holding.
[0007] At least two blade assemblies are slidably disposed within the slicing space, and the distance between adjacent blade assemblies is adjustable. Each blade assembly includes a blade support frame and a blade inserted into the blade support frame. The blade support frame is provided with a guide block that slides into the guide groove.
[0008] The guide groove is a T-shaped groove, and the guide block is a T-shaped slider that is adapted to the T-shaped groove.
[0009] The blade support frame has a U-shaped structure, and the guide blocks are located on both sides of the open end of the U-shaped structure.
[0010] The blade support frame has slots for holding the blade.
[0011] The blade has lugs on both sides, and when the blade support frame is engaged with the main frame, the lugs are located above the vertical section.
[0012] The operating part is covered with an anti-slip layer.
[0013] The two ends of the closed section are interference-fitted with the guide groove.
[0014] The vertical section is equipped with a scale that runs along the guide groove.
[0015] The beneficial effects of this utility model are as follows: by setting at least two blade assemblies with adjustable relative positions, and by adjusting the distance between them, brain tissue slices can be formed in one slice. At the same time, the two blade assemblies can be used to directly extract the sliced brain tissue without easily damaging the brain tissue slices. Attached Figure Description
[0016] Figure 1 This is a schematic diagram of the structure of this utility model.
[0017] Figure 2 This is the front view of the present invention.
[0018] Figure 3 This is a cross-sectional schematic diagram of the present invention.
[0019] Figure 4 This is a schematic diagram of the main frame of this utility model.
[0020] Figure 5 This is a schematic diagram of the blade holder of this utility model. Detailed Implementation
[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0022] It should be noted that all directional indicators (such as up, down, left, right, front, back, etc.) in this utility model embodiment are only used to explain the relative positional relationship and movement of each component in a certain specific posture (as shown in the figure). If the specific posture changes, the directional indicator will also change accordingly.
[0023] This invention provides a brain tissue slicing tool suitable for the brain groove. The brain tissue slicing tool can be used in conjunction with the brain groove. It includes a main frame and at least two blade assemblies that are adjustablely arranged on the main frame. This embodiment takes two blade assemblies as an example.
[0024] The main frame 100 includes a horizontal section 110 and two vertical sections 120 arranged vertically. A slicing space 130 for accommodating a cutter is formed between the two vertical sections 120. The whole frame is U-shaped and the three components are integrated into one design. The blade assembly is used for slicing between the two vertical sections. Guide grooves 121 are provided on the two vertical sections 120 along the length of the vertical section 120. A detachable closed section 300 is provided at the other end of the vertical section 120. The closed section 300, the horizontal section 110 and the two vertical sections 120 form a rectangular frame. Hand-held operating parts 200 are provided on both sides of the rectangular frame.
[0025] The closing section directly seals the guide groove and the U-shaped opening, which is the inlet of the slicing space. In use, the assembled blade assembly must first be inserted along the opening end of the guide groove, and its position adjusted. Then, the closing section seals the entire guide groove, completing the assembly of the brain tissue slicing tool. The length of the guide groove is preferably matched to the length of the vertical section. On the opening side of the vertical section, one end of the guide groove has a notch 122 to facilitate the insertion of the closing section.
[0026] Two blade assemblies are slidably disposed within the slicing space 130, and the distance between adjacent blade assemblies is adjustable. Each blade assembly includes a blade support frame 400 and a blade 500 inserted into the blade support frame 400. The blade support frame 400 is provided with a guide block 410 that slides into the guide groove 121.
[0027] By adjusting the position of the guide block within the guide groove, the distance between the two blade assemblies can be changed, thereby enabling the acquisition of brain tissue slices of different thicknesses.
[0028] In this embodiment, the guide groove 121 is a T-shaped groove, and the guide block 410 is a T-shaped slider adapted to the T-shaped groove. In other embodiments, the guide groove can also be of other shapes, such as a dovetail groove.
[0029] The blade support frame 400 has a U-shaped structure, and the guide blocks 410 are located on both sides of the open end of the U-shaped structure. The blade support frame is set vertically to the main frame, and the guide groove opening of the main frame faces upward. The vertical section and the blade support frame are used to limit the blade and prevent the blade from shaking, which would affect the slicing effect.
[0030] The blade support frame 400 is provided with a slot 420 for clamping the blade 500. The thickness of the slot is adapted to the blade. Preferably, several oppositely arranged protrusions can be provided in the slot to make the clamping of the blade more secure and reliable.
[0031] The blade 500 has lugs 510 on both sides. When the blade support frame 400 is engaged with the main frame 100, the lugs 510 are located above the vertical section 120. Ordinary razor blades with lugs can be used. The lugs at both ends can be limited by the vertical section from the bottom, and the upper end of the blade is limited by the blade support frame, thereby ensuring that the installed blade is firmly fixed on the blade support frame.
[0032] The operating part 200 is covered with an anti-slip layer 210, which can be tape, nylon, or sponge.
[0033] The two ends of the closed section 300 form an interference fit with the guide groove 121. Alternatively, a snap-fit method can be used, such as setting an undercut on the upper and lower sides of the notch and setting an oblique opening at the corresponding closed section. The two work together to fix the parts, making the fixation more secure.
[0034] The vertical section 120 is provided with a scale along the guide groove 121. The scale is set on the surface of the vertical section by laser etching or drawing, and is used to precisely adjust the distance between the two blade assemblies.
[0035] The embodiments should not be regarded as limitations on the present invention, but any improvements made based on the spirit of the present invention should be within the protection scope of the present invention.
Claims
1. A brain tissue slicing tool suitable for the cerebral sulcus, characterized in that: It includes: The main frame (100) includes a horizontal section (110) and two vertical sections (120) arranged vertically. A slicing space (130) for accommodating a cutter is formed between the two vertical sections (120). Guide grooves (121) are provided on the two vertical sections (120) along the length of the vertical section (120). A detachable closed section (300) is provided at the other end of the vertical section (120). The closed section (300), the horizontal section (110) and the two vertical sections (120) form a rectangular frame. Hand-held operating parts (200) are provided on both sides of the rectangular frame. At least two blade assemblies are slidably disposed within the slicing space (130), and the distance between adjacent blade assemblies is adjustable. Each blade assembly includes a blade support frame (400) and a blade (500) inserted into the blade support frame (400). The blade support frame (400) is provided with a guide block (410) that slides into the guide groove (121).
2. The brain tissue slicing tool suitable for the cerebral sulcus according to claim 1, characterized in that: The guide groove (121) is a T-shaped groove, and the guide block (410) is a T-shaped slider that is adapted to the T-shaped groove.
3. The brain tissue slicing tool suitable for the cerebral sulcus according to claim 1, characterized in that: The blade support frame (400) has a U-shaped structure, and the guide block (410) is located on both sides of the opening end of the U-shaped structure.
4. The brain tissue slicing tool suitable for the cerebral sulcus according to claim 3, characterized in that: The blade support (400) is provided with a slot (420) for holding the blade (500).
5. The brain tissue slicing tool suitable for the cerebral sulcus according to claim 3 or 4, characterized in that: The blade (500) has lugs (510) on both sides, and when the blade support frame (400) is engaged with the main frame (100), the lugs (510) are located above the vertical section (120).
6. The brain tissue slicing tool suitable for the cerebral sulcus according to claim 1, characterized in that: The operating part (200) is covered with an anti-slip layer (210).
7. The brain tissue slicing tool suitable for the cerebral sulcus according to claim 1, characterized in that: The two ends of the closed section (300) are interference-fitted with the guide groove (121).
8. The brain tissue slicing tool suitable for the cerebral sulcus according to claim 1, characterized in that: The vertical section (120) is provided with a scale along the guide groove (121).