Chromosome micronucleus dropping device

Abstract

The utility model belongs to the technical field of piece dropping devices, and particularly relates to a chromosome micronucleus piece dropping device which comprises a bottom plate, a support is fixedly installed on the bottom plate, a piece dropping assembly is arranged on the support, an annular groove is fixedly embedded in the bottom plate, a disc is arranged in the annular groove, a driving motor is fixedly installed in the annular groove, and the driving motor is connected with the disc. Grooves are formed in the disc in an array mode, grating plates are fixedly installed in the grooves, and jet heads are fixedly installed on the grating plates. According to the chromosome micronucleus dropping device, redundant liquid generated during dropping of the chromosome micronucleus dropping device can be conveniently collected through the installed groove, the redundant liquid can enter the groove in the dropping period and flow to the bottom of the groove through the grating plate to be stored, then the redundant liquid can be effectively prevented from flowing in the dropping period, and the dropping efficiency of the chromosome micronucleus dropping device is improved. In the later period, collection and removal are not easy, the liquid outlet head is not sealed any more, and then the liquid collected in the groove can flow to the outside to be removed.

Description

Technical Field

[0001] This utility model relates to the field of droplet device technology, specifically a chromosome micronucleus droplet device. Background Technology

[0002] The chromosome micronucleus drop device is a laboratory instrument specifically designed for the preparation and observation of chromosomes in cell samples, particularly for the study of micronuclei. Micronuclei are small, independent nuclei within cells, typically formed during cell division due to chromosome breakage or abnormal meiosis. The chromosome micronucleus drop device allows for the rapid and efficient preparation of cell drops from which the presence of chromosomes and micronuclei can be observed. It can also quickly fix cells to maintain their structure and morphology, facilitating subsequent staining and microscopic observation. By forming a thin, uniform cell layer, it facilitates microscopic observation, improving the accuracy and reproducibility of chromosome morphology and micronucleus analysis. It is highly adaptable and can be used for different types of cells, including cultured cells and other tissue samples.

[0003] Existing chromosome micronucleus drop devices are not convenient for collecting excess liquid generated during drop preparation. The excess liquid generated during the preparation process still needs to be manually cleaned by the operator, which causes additional workload and potential cross-contamination risks, affecting work efficiency and the cleanliness of the laboratory environment.

[0004] Patent document CN212674570U discloses an automated chromosome slicing device, "including a base, an electric push rod mounted on the base, a circular plate rotatably mounted on the electric push rod, a plurality of glass slides spaced around the circular plate, a carrier cylinder rotatably mounted on the base, and a loading plate integrally mounted on the upper end of the carrier cylinder, droppers detachably mounted on both sides of the loading plate, and a drive ring rotatably mounted on the loading plate coaxially with the carrier cylinder. Moreover, in this solution, when the cell fluid in one dropper is depleted, the other dropper in standby mode can be rotated to the working position, which can greatly improve the chromosome slicing efficiency when dealing with batches of chromosome slicing." However, the automated chromosome slicing device in the aforementioned published literature mainly considers improving chromosome slicing efficiency, but does not consider the problem of collecting excess liquid generated by the slicing. Therefore, it is necessary to develop a chromosome micronucleus slicing device. Utility Model Content

[0005] The purpose of this invention is to provide a chromosome micronucleus droplet device to solve the technical problem mentioned in the background art of the inconvenience of collecting excess liquid generated by the droplets.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a chromosome micronucleus dropper device, comprising a base plate, a support fixedly mounted on the base plate, a dropper assembly disposed on the support, an annular groove fixedly embedded inside the base plate, a disc disposed inside the annular groove, a drive motor fixedly mounted inside the annular groove, and the output end of the drive motor fixedly connected to the center position of the disc, grooves arrayed on the disc, a grid plate fixedly mounted inside the grooves, an air jet fixedly mounted on the grid plate, a liquid outlet head corresponding to the grooves mounted on the disc, and the liquid outlet head communicating with the grooves, and a wind power assembly installed inside the disc.

[0007] Preferably, a pad is fixedly installed at the bottom of the base plate.

[0008] Preferably, the dropper assembly includes a dropper head, a delivery pipe, a storage tank, and a pump. The dropper head is fixedly mounted on a bracket, the delivery pipe is connected to the top of the dropper head, the storage tank is fixedly mounted on the back of the bracket, the pump is fixedly mounted on the storage tank, and the pump input end is connected to the storage tank. The other end of the delivery pipe is connected to the pump output end. A battery assembly is fixedly mounted on the bottom of the base plate, and the battery assembly is electrically connected to the pump and the drive motor respectively.

[0009] Preferably, a storage battery is embedded inside the disc, and the storage battery is located on one side of the groove, with a controller fixedly installed on the storage battery.

[0010] Preferably, a storage tank is embedded inside the disc, an injection head is installed on the top of the storage tank, a mounting frame is fixedly connected to the bottom of the storage tank, a micro water pump is fixedly installed inside the mounting frame, and the input end of the micro water pump is connected to the inside of the storage tank. The controller and the battery are both electrically connected to the micro water pump.

[0011] Preferably, a spray head corresponding to the groove is fixedly installed on the disc, and the input end of the spray head is connected to the output end of the micro water pump through a pipe.

[0012] Preferably, the wind power component includes a wind duct, a filter screen, and a micro fan. The wind duct is fixedly installed inside the disc, the filter screen is fixedly installed at one end of the wind duct, and the micro fan is fixedly installed inside the wind duct. The micro fan is electrically connected to the controller and the battery, and the output end of the micro fan is connected to the jet head through a pipe.

[0013] Compared with the prior art, the beneficial effects of this utility model are:

[0014] 1. This utility model uses a groove to facilitate the collection of excess liquid generated during the dispensing of chromosome micronucleus smears. During the dispensing process, excess liquid enters the groove and flows through the grid plate to the bottom of the groove for storage. This effectively prevents excess liquid from flowing during the dispensing process and making it difficult to collect and remove later. The liquid outlet is no longer sealed, and the liquid collected inside the groove flows to the outside for removal.

[0015] 2. This utility model uses an installed jet head to facilitate the drying and cleaning of the bottom of the slide after the chromosome micronucleus dispensing device is applied. The operation of the micro fan draws air from inside the air duct, thereby generating wind. The wind flows through the pipe to the inside of the jet head, and through the jet head, the wind flows to the bottom of the slide, thereby drying the bottom of the slide and improving the drying efficiency of the slide.

[0016] 3. This utility model facilitates the coating of cell suspension onto glass slides by using a chromosome micronucleus dropper device through the installed storage tank and spray head. When coating the glass slide with cell suspension to promote cell adhesion, after the glass slide is placed inside the groove, the micro water pump operates to draw the cell suspension stored in the storage tank. The cell suspension flows into the spray head through the pipe, and the spray head sprays the cell suspension onto the surface of the glass slide, thereby facilitating the coating of the cell suspension onto the glass slide surface and improving the adhesion of the glass slide. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0018] Figure 2 This is a schematic diagram of the base plate structure of this utility model;

[0019] Figure 3 This is a schematic diagram of the storage tank structure of this utility model;

[0020] Figure 4 This is a schematic diagram of the ventilation duct structure of this utility model.

[0021] In the diagram: 1. Base plate; 2. Pad block; 3. Bracket; 4. Dropper head; 5. Delivery pipe; 6. Storage tank; 7. Pump; 8. Battery assembly; 9. Annular groove; 10. Drive motor; 11. Disc; 12. Groove; 13. Grating plate; 14. Dispensing head; 15. Battery; 16. Controller; 17. Storage tank; 18. Injection head; 19. Mounting bracket; 20. Miniature water pump; 21. Spray head; 22. Jet nozzle; 23. Air duct; 24. Filter screen; 25. Miniature fan. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0023] Please see Figures 1 to 4 A chromosome micronucleus dropper includes a base plate 1, a support 3 fixedly mounted on the base plate 1, a dropper assembly mounted on the support 3, an annular groove 9 fixedly embedded inside the base plate 1, a disc 11 disposed inside the annular groove 9, a drive motor 10 fixedly mounted inside the annular groove 9, and the output end of the drive motor 10 fixedly connected to the center of the disc 11. Grooves 12 are arrayed on the disc 11, a grid plate 13 is fixedly mounted inside the grooves 12, and a jet nozzle 22 is fixedly mounted on the grid plate 13. A liquid outlet 14 corresponding to the grooves 12 is mounted on the disc 11 and is connected to the grooves 12. A wind-powered assembly is installed inside the disc 11. When using the chromosome micronucleus dropper, after placing the slide inside the groove 12, the grid plate 13 supports the slide through the jet nozzle 22, and the drive motor... The operation of the machine 10 drives the disk 11 to rotate, thereby adjusting the position of the glass slide. After the glass slide is moved to the bottom of the dispensing assembly, the dispensing assembly delivers the chromosome micronuclei for dispensing, causing them to fall onto the glass slide. The drive motor 10 continues to work, moving the next set of glass slides to the dispensing location for dispensing, thus improving work efficiency and enabling batch dispensing of chromosome micronuclei. During the dispensing process, excess liquid enters the groove 12 and flows through the grid plate 13 to the bottom of the groove 12 for storage, effectively preventing excess liquid from flowing during the dispensing process and making it difficult to collect and remove later. At the same time, the operation of the wind power component generates wind that enters the air jet 22, which directs the wind to the bottom of the glass slide, drying the bottom of the glass slide and improving the drying efficiency of the glass slide.

[0024] Please see Figure 1 A pad 2 is fixedly installed at the bottom of the base plate 1, which can support the base plate 1.

[0025] Please see Figure 1 and Figure 2The slide-dispensing assembly includes a slide-dispensing head 4, a delivery tube 5, a liquid storage tank 6, and a pump 7. The slide-dispensing head 4 is fixedly mounted on a bracket 3. The delivery tube 5 is connected to the top of the slide-dispensing head 4. The liquid storage tank 6 is fixedly mounted on the back of the bracket 3. The pump 7 is fixedly mounted on the liquid storage tank 6, and the input end of the pump 7 is connected to the liquid storage tank 6. The other end of the delivery tube 5 is connected to the output end of the pump 7. A battery assembly 8 is fixedly mounted on the bottom of the base plate 1, and the battery assembly 8 is electrically connected to the pump 7 and the drive motor 10. After the slide is moved to the slide-dispensing location, the pump 7 is activated to extract the chromosome micronuclei inside the liquid storage tank 6. The liquid flows into the slide-dispensing head 4 through the delivery tube 5. Through the slide-dispensing head 4, the chromosome micronucleus liquid drips onto the surface of the slide, thus achieving the purpose of slide dispensing. A switch is provided on the pump 7 to control its operation.

[0026] Please see Figure 1 The disk 11 has a battery 15 embedded inside, and the battery 15 is located on one side of the groove 12. The controller 16 is fixedly installed on the battery 15. The disk 11 provides installation space for the battery 15, and the battery 15 provides installation space for the controller 16.

[0027] Please see Figure 1 and Figure 3 A storage tank 17 is embedded inside the disc 11. An injection head 18 is installed on the top of the storage tank 17. A mounting bracket 19 is fixedly connected to the bottom of the storage tank 17. A micro water pump 20 is fixedly installed inside the mounting bracket 19, and the input end of the micro water pump 20 is connected to the inside of the storage tank 17. The controller 16 and the battery 15 are both electrically connected to the micro water pump 20. A spray head 21 corresponding to the groove 12 is fixedly installed on the disc 11, and the input end of the spray head 21 is connected to the output end of the micro water pump 20 through a pipe. Storage tank 17 is used to store cell suspension. The cell type used has poor adhesion to the glass slide. To promote cell adhesion, the glass slide is coated with cell suspension. After the glass slide is placed inside the groove 12, the micro water pump 20 is activated to extract the cell suspension stored in storage tank 17. The cell suspension flows into the spray head 21 through the pipe. The spray head 21 sprays the cell suspension onto the surface of the glass slide, which facilitates the coating of the cell suspension onto the surface of the glass slide and improves the adhesion of the glass slide.

[0028] Please see Figure 4The wind power assembly includes a wind duct 23, a filter 24, and a miniature fan 25. The wind duct 23 is fixedly installed inside the disc 11, the filter 24 is fixedly installed at one end of the wind duct 23, and the miniature fan 25 is fixedly installed inside the wind duct 23. The miniature fan 25 is electrically connected to the controller 16 and the battery 15. The output end of the miniature fan 25 is connected to the jet head 22 through a pipe. When the wind power assembly is working, the miniature fan 25 will draw air from inside the wind duct 23, thereby generating wind. The wind flows through the pipe to the inside of the jet head 22, and through the jet head 22, the wind will flow to the bottom of the glass slide, thereby drying the bottom of the glass slide.

[0029] Working principle: First, when using the chromosome micronucleus dispensing device, the slide is placed inside the groove 12. The grid plate 13 supports the slide through the jet head 22. The drive motor 10 rotates the disk 11, adjusting the position of the slide. After the slide is moved below the dispensing assembly, the pump 7 extracts the chromosome micronuclei from the storage tank 6. The liquid flows through the delivery pipe 5 into the dispensing head 4, where it drips onto the surface of the slide, thus achieving the dispensing purpose. The drive motor 10 continues to move the next set of slides to the dispensing location for processing, thereby improving work efficiency and allowing for batch processing of chromosome micronuclei. During dispensing, excess liquid enters the groove 12, flows through the grid plate 13, and is stored at the bottom of the groove 12. To effectively prevent excess liquid from flowing during slide application and making subsequent collection and removal difficult, the micro fan 25 operates to draw air from inside the air duct 23, generating airflow. This airflow travels through pipes to the nozzle 22, directing the airflow towards the bottom of the slide for drying, thus improving the drying efficiency. The storage container 17 stores cell suspensions. Since the cell type used has poor adhesion to the slide, to promote cell adhesion, the slide is placed inside the groove 12, and the micro water pump 20 operates to draw the cell suspension stored in the storage container 17. This suspension flows through pipes into the spray head 21, which sprays the cell suspension onto the slide surface, facilitating coating and improving adhesion.

[0030] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

Claims

1. A chromosome micronucleus droplet device, comprising a base plate (1), characterized in that: A bracket (3) is fixedly installed on the base plate (1). A dropper assembly is provided on the bracket (3). An annular groove (9) is fixedly embedded inside the base plate (1). A disc (11) is provided inside the annular groove (9). A drive motor (10) is fixedly installed inside the annular groove (9). The output end of the drive motor (10) is fixedly connected to the center position of the disc (11). Grooves (12) are arranged in an array on the disc (11). A grid plate (13) is fixedly installed inside the groove (12). A jet nozzle (22) is fixedly installed on the grid plate (13). A liquid outlet (14) corresponding to the groove (12) is installed on the disc (11). The liquid outlet (14) is connected to the groove (12). A wind power assembly is installed inside the disc (11).

2. The chromosome micronucleus droplet device according to claim 1, characterized in that: The bottom of the base plate (1) is fixedly installed with a pad (2).

3. The chromosome micronucleus droplet device according to claim 1, characterized in that: The dropper assembly includes a dropper head (4), a delivery pipe (5), a storage tank (6), and a pump (7). The dropper head (4) is fixedly mounted on the bracket (3). The delivery pipe (5) is connected to the top of the dropper head (4). The storage tank (6) is fixedly mounted on the back of the bracket (3). The pump (7) is fixedly mounted on the storage tank (6), and the input end of the pump (7) is connected to the storage tank (6). The other end of the delivery pipe (5) is connected to the output end of the pump (7). A battery assembly (8) is fixedly mounted on the bottom of the base plate (1), and the battery assembly (8) is electrically connected to the pump (7) and the drive motor (10) respectively.

4. The chromosome micronucleus droplet device according to claim 1, characterized in that: The disk (11) is inlaid with a storage battery (15), and the storage battery (15) is located on one side of the groove (12). A controller (16) is fixedly installed on the storage battery (15).

5. A chromosome micronucleus droplet device according to claim 4, characterized in that: The disc (11) is embedded with a storage tank (17), and an injection head (18) is installed on the top of the storage tank (17). A mounting frame (19) is fixedly connected to the bottom of the storage tank (17). A micro water pump (20) is fixedly installed inside the mounting frame (19), and the input end of the micro water pump (20) is connected to the inside of the storage tank (17). The controller (16) and the battery (15) are both electrically connected to the micro water pump (20).

6. A chromosome micronucleus droplet device according to claim 5, characterized in that: The disc (11) is fixedly mounted with a spray head (21) corresponding to the groove (12), and the input end of the spray head (21) is connected to the output end of the micro water pump (20) through a pipe.

7. The chromosome micronucleus droplet device according to claim 1, characterized in that: The wind power assembly includes a wind duct (23), a filter screen (24), and a miniature fan (25). The wind duct (23) is fixedly installed inside the disc (11). The filter screen (24) is fixedly installed at one end of the wind duct (23). The miniature fan (25) is fixedly installed inside the wind duct (23). The miniature fan (25) is electrically connected to the controller (16) and the battery (15). The output end of the miniature fan (25) is connected to the jet head (22) through a pipe.

Images