Solid tumor immune microenvironment detection and analysis equipment

Abstract

The utility model relates to the technical field of detection and analysis equipment, and discloses solid tumor immune microenvironment detection and analysis equipment which comprises an equipment main machine, a cavity is formed in the upper surface of the equipment main machine, and a sealing cover is rotationally connected to an opening of the cavity through a rotating shaft. A transparent detection groove is fixedly installed in the cavity through an installation frame, a detection light source is arranged in the cavity and located under the transparent detection groove, a spectrum receiving assembly is installed on the sealing cover, and an electric guide rail is installed on the sealing cover. The electric guide rail can drive the detection groove sealing cover to move to the position below the spectrum receiving assembly, at the moment, the sealing cover covers the opening portion of the cavity, the detection groove sealing cover covers the opening portion of the upper end of the transparent detection groove at the same time, and residual samples in the transparent detection groove are cleaned through the cleaning assembly. The influence of sample residues on the accuracy of subsequent detection data is avoided.

Description

Technical Field

[0001] This utility model relates to the field of detection and analysis equipment technology, and in particular to a detection and analysis device for the immune microenvironment of solid tumors. Background Technology

[0002] When diagnosing cancer patients, it is necessary to extract samples and perform immune tests. Immunoassay analyzers are various detection and analysis devices based on the principle of immune response specificity. They are widely used in the life sciences field and are used to analyze specific molecules in samples such as body fluids, serum, plasma, and whole blood.

[0003] During the detection and analysis process of immunoassay analyzers, fluid samples need to be placed in the detection tank, and the samples are then analyzed by spectroscopy.

[0004] In existing technologies, samples remain inside the detection tank after the detection is completed. If the inside of the detection tank is not cleaned, bacteria can easily grow inside the detection tank, and the residual samples will affect the accuracy of subsequent detection data. To address this, we propose a solid tumor immune microenvironment detection and analysis device. Utility Model Content

[0005] This invention provides a device for detecting and analyzing the immune microenvironment of solid tumors, which solves the technical problem that after the detection is completed, there will be residual samples inside the detection tank. If the inside of the detection tank is not cleaned, bacteria will easily grow inside the detection tank, and the residual samples will affect the accuracy of subsequent detection data.

[0006] To solve the above-mentioned technical problems, this utility model provides a solid tumor immune microenvironment detection and analysis device, including a main unit. The upper surface of the main unit is provided with a cavity. A sealing cover is rotatably connected to the opening of the cavity via a rotating shaft. A transparent detection slot is fixedly installed inside the cavity via a mounting bracket. A detection light source is provided inside the cavity and is located directly below the transparent detection slot. A spectral receiving component is installed on the sealing cover. An electric guide rail is installed on the sealing cover. The moving end of the electric guide rail is fixedly installed with the detection slot sealing cover via a bracket. A cleaning component is installed on the detection slot sealing cover.

[0007] Preferably, the cleaning component includes an atomizing nozzle fixedly installed on the lower surface of the test tank sealing cover, the upper end of the atomizing nozzle extending to the outside of the upper surface of the test tank sealing cover and connected to a water supply system via a water delivery hose.

[0008] Preferably, the cleaning assembly further includes a negative pressure suction tube fixedly installed on the lower surface of the detection tank sealing cover, the upper end of the negative pressure suction tube extending to the outside of the upper surface of the detection tank sealing cover and connected to a negative pressure pump through a negative pressure pipe.

[0009] Preferably, the lower end of the negative pressure straw has a sliding sleeve, the lower end of the sleeve has a suction port, and the upper end of the sleeve is fixedly connected to a support spring. The support spring is movably sleeved on the outside of the negative pressure straw, and the upper end of the support spring is fixed to the outer wall of the negative pressure straw by a fixing bracket.

[0010] Preferably, the inner surface of the transparent detection groove is inclined, and the suction port is oriented towards the low-lying area inside the transparent detection groove.

[0011] Preferably, the cleaning assembly further includes a gas nozzle fixedly installed on the lower surface of the test tank sealing cover, the upper end of the gas nozzle extending to the outside of the upper surface of the test tank sealing cover and connected to an air pump via a gas hose.

[0012] Preferably, a control module is mounted on the outer surface of the device host.

[0013] Compared with related technologies, the solid tumor immune microenvironment detection and analysis device provided by this utility model has the following beneficial effects:

[0014] During use, the electric guide rail can drive the detection slot sealing cover to move below the spectral receiving component. At this time, the sealing cover is closed on the cavity opening, and the detection slot sealing cover is closed on the upper opening of the transparent detection slot. The cleaning component is used to clean the sample remaining inside the transparent detection slot to avoid the sample residue affecting the accuracy of subsequent detection data.

[0015] During the cleaning of the transparent testing tank, the inflow of air increases the turbulence and fluidity of the water flow, enhancing the flushing effect on the inner wall of the transparent testing tank and improving the cleaning effect. After the water and sample residue inside the transparent testing tank are discharged and the cleaning is completed, the airflow sprayed into the transparent testing tank can be discharged through the negative pressure suction tube and negative pressure tube. In this process, the airflow flowing into the transparent testing tank greatly improves the air circulation inside the transparent testing tank, which can quickly dry the residual water stains, allowing the equipment to quickly carry out subsequent testing work and avoid water stain residue. Attached Figure Description

[0016] Figure 1 A schematic diagram of the overall structure of a device for detecting and analyzing the immune microenvironment of solid tumors;

[0017] Figure 2 This is a schematic diagram of the internal structure of the main unit of a device for detecting and analyzing the immune microenvironment of solid tumors.

[0018] Figure 3 A schematic diagram of the structure of the sealing cover of the detection tank in a solid tumor immune microenvironment detection and analysis device;

[0019] Figure 4This is a schematic diagram of the structure of a transparent detection tank in a device for detecting and analyzing the immune microenvironment of solid tumors.

[0020] The diagram shows the following components: 1. Main unit; 2. Control module; 3. Cavity; 4. Sealing cover; 5. Transparent detection tank; 51. Mounting bracket; 6. Detection light source; 7. Spectrum receiving component; 8. Electric guide rail; 81. Detection tank sealing cover; 9. Cleaning component; 91. Atomizing nozzle; 911. Water delivery hose; 92. Negative pressure suction tube; 921. Negative pressure tube; 922. Tube sleeve; 923. Suction port; 924. Support spring; 93. Gas nozzle; 931. Gas hose. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] Example 1, by Figure 1-4 This invention discloses a device for detecting and analyzing the immune microenvironment of solid tumors, comprising a main unit 1, a cavity 3 on the upper surface of the main unit 1, a sealing cover 4 rotatably connected to the opening of the cavity 3 via a rotating shaft, a transparent detection groove 5 fixedly mounted inside the cavity 3 via a mounting bracket 51, a detection light source 6 disposed inside the cavity 3, located directly below the transparent detection groove 5, and a spectral receiving component 7 mounted on the sealing cover 4. When the sealing cover 4 is closed at the opening of the cavity 3, the spectral receiving component 7 is located directly above the transparent detection groove 5, and the detection light source 6 illuminates upwards from below the transparent detection groove 5, while the spectral receiving component 7 receives the spectrum transmitted through the sample. The information is transmitted to the analysis host for analysis and detection, thereby completing the immunoassay. An electric guide rail 8 is installed on the sealing cover 4. The moving end of the electric guide rail 8 is fixedly installed with the detection slot sealing cover 81 via a bracket. A cleaning component 9 is installed on the detection slot sealing cover 81. In use, the electric guide rail 8 can drive the detection slot sealing cover 81 to move below the spectral receiving component 7. At this time, the sealing cover 4 is closed at the opening of the cavity 3, and the detection slot sealing cover 81 is closed at the upper opening of the transparent detection slot 5. The cleaning component 9 cleans the sample remaining inside the transparent detection slot 5 to avoid the sample residue affecting the accuracy of subsequent detection data.

[0023] In this embodiment, the cleaning component 9 includes an atomizing nozzle 91 fixedly installed on the lower surface of the detection tank sealing cover 81. The upper end of the atomizing nozzle 91 extends to the outside of the upper surface of the detection tank sealing cover 81 and is connected to a water supply system through a water supply hose 911. In use, water is supplied to the water supply hose 911 and the interior of the atomizing nozzle 91 through the water supply system, and the water is atomized and sprayed onto the inner wall of the transparent detection tank 5 through the atomizing nozzle 91 to rinse the inner wall of the transparent detection tank 5.

[0024] In this embodiment, the cleaning assembly 9 further includes a negative pressure suction tube 92 fixedly installed on the lower surface of the detection tank sealing cover 81. The upper end of the negative pressure suction tube 92 extends to the outside of the upper surface of the detection tank sealing cover 81 and is connected to a negative pressure pump through a negative pressure pipe 921. A sleeve 922 slides on the outer wall of the lower end of the negative pressure suction tube 92. A suction port 923 is opened at the lower end of the sleeve 922. A support spring 924 is fixedly connected to the upper end of the sleeve 922. The support spring 924 is movably sleeved on the outside of the negative pressure suction tube 92. The end is fixed to the outer wall of the negative pressure suction tube 92 by a fixing bracket. When the detection tank sealing cover 81 is closed on the transparent detection tank 5, the support spring 924 will extend and retract to apply elastic force to press the tube sleeve 922 against the inner wall of the transparent detection tank 5, so that the suction port 923 is located on the inner surface of the transparent detection tank 5. At this time, the negative pressure pump starts, which generates negative pressure suction between the negative pressure suction tube 92 and the inside of the tube sleeve 922. The cleaned water and the test sample can be sucked in through the suction port 923 to avoid them remaining inside the transparent detection tank 5 and improve the cleaning effect.

[0025] In this embodiment, the inner surface of the transparent detection tank 5 is inclined, and the suction port 923 is set towards the low-lying area inside the transparent detection tank 5. This setting allows the water inside the transparent detection tank 5 to flow towards the low-lying area and easily enter the suction port 923.

[0026] In this embodiment, the cleaning component 9 also includes a gas nozzle 93 fixedly installed on the lower surface of the detection tank sealing cover 81. The upper end of the gas nozzle 93 extends to the outside of the upper surface of the detection tank sealing cover 81 and is connected to an air pump through a gas hose 931. In use, the air pump can input air into the gas hose 931 and the gas nozzle 93, and spray it into the transparent detection tank 5 through the gas nozzle 93. When cleaning the transparent detection tank 5, the air inflow can increase the turbulence and fluidity of the water flow, improve the flushing effect of the water flow on the inner wall of the transparent detection tank 5, and improve the cleaning effect. After the water flow and sample residue inside the transparent detection tank 5 are discharged and the cleaning is completed, the airflow sprayed into the transparent detection tank 5 can be discharged through the negative pressure suction tube 92 and the negative pressure tube 921. In this process, the airflow flowing into the transparent detection tank 5 greatly improves the airflow inside the transparent detection tank 5, which can quickly dry the residual water stains, so that the equipment can quickly carry out subsequent detection work and avoid water stain residue.

[0027] In this embodiment, a control module 2 is installed on the outer surface of the device host 1. The control module 2 is electrically connected to the electric guide rail 8 and can control the electric guide rail 8 to start and stop.

[0028] Working principle:

[0029] During use, the electric guide rail 8 can drive the detection slot sealing cover 81 to move below the spectral receiving component 7. At this time, the sealing cover 4 is closed on the opening of the cavity 3, and the detection slot sealing cover 81 is closed on the upper opening of the transparent detection slot 5. The cleaning component 9 cleans the sample remaining inside the transparent detection slot 5 to avoid the sample residue affecting the accuracy of subsequent detection data.

[0030] During use, water is supplied to the water supply hose 911 and the atomizing nozzle 91 through the water supply system, and the water is atomized and sprayed onto the inner wall of the transparent detection tank 5 through the atomizing nozzle 91 to rinse the inner wall of the transparent detection tank 5.

[0031] During the cleaning of the transparent detection tank 5, the inflow of air can increase the turbulence and fluidity of the water flow, enhance the flushing effect of the water flow on the inner wall of the transparent detection tank 5, and improve the cleaning effect. After the water and sample residue inside the transparent detection tank 5 are discharged and the cleaning is completed, the airflow sprayed into the transparent detection tank 5 can be discharged through the negative pressure suction tube 92 and the negative pressure tube 921. In this process, the airflow flowing into the transparent detection tank 5 greatly improves the air circulation inside the transparent detection tank 5, which can quickly dry the residual water stains, allowing the equipment to quickly carry out subsequent testing work and avoid water stain residue.

[0032] Activating the negative pressure pump creates negative pressure suction inside the negative pressure suction tube 92 and the sleeve 922. The cleaned water and the test sample can be sucked in through the suction port 923, preventing them from remaining inside the transparent test tank 5 and improving the cleaning effect.

[0033] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A device for detecting and analyzing the immune microenvironment of solid tumors, comprising a main unit (1), characterized in that: The upper surface of the main unit (1) of the device is provided with a cavity (3). A sealing cover (4) is rotatably connected to the opening of the cavity (3) through a rotating shaft. A transparent detection slot (5) is fixedly installed inside the cavity (3) through a mounting bracket (51). A detection light source (6) is provided inside the cavity (3). The detection light source (6) is located directly below the transparent detection slot (5). A spectrum receiving component (7) is installed on the sealing cover (4). An electric guide rail (8) is installed on the sealing cover (4). The moving end of the electric guide rail (8) is fixedly installed with a detection slot sealing cover (81) through a bracket. A cleaning component (9) is installed on the detection slot sealing cover (81).

2. The solid tumor immune microenvironment detection and analysis device according to claim 1, characterized in that, The cleaning component (9) includes an atomizing nozzle (91) fixedly installed on the lower surface of the detection tank sealing cover (81), the upper end of the atomizing nozzle (91) extending to the outside of the upper surface of the detection tank sealing cover (81) and connected to a water supply system via a water supply hose (911).

3. The solid tumor immune microenvironment detection and analysis device according to claim 2, characterized in that, The cleaning assembly (9) also includes a negative pressure suction tube (92) fixedly installed on the lower surface of the detection tank sealing cover (81). The upper end of the negative pressure suction tube (92) extends to the outside of the upper surface of the detection tank sealing cover (81) and is connected to a negative pressure pump through a negative pressure pipe (921).

4. The solid tumor immune microenvironment detection and analysis device according to claim 3, characterized in that, The lower end of the negative pressure straw (92) has a tube sleeve (922) that slides on its outer wall. The lower end of the tube sleeve (922) has a suction port (923). The upper end of the tube sleeve (922) is fixedly connected to a support spring (924). The support spring (924) is movably sleeved on the outside of the negative pressure straw (92). The upper end of the support spring (924) is fixed to the outer wall of the negative pressure straw (92) by a fixing bracket.

5. The solid tumor immune microenvironment detection and analysis device according to claim 4, characterized in that, The inner surface of the transparent detection groove (5) is inclined, and the suction port (923) is oriented towards the low-lying area inside the transparent detection groove (5).

6. The solid tumor immune microenvironment detection and analysis device according to claim 5, characterized in that, The cleaning assembly (9) also includes a gas nozzle (93) fixedly installed on the lower surface of the detection tank sealing cover (81), the upper end of the gas nozzle (93) extending to the outside of the upper surface of the detection tank sealing cover (81) and connected to an air pump via a gas hose (931).

7. The solid tumor immune microenvironment detection and analysis device according to claim 6, characterized in that, The device host (1) has a control module (2) mounted on its outer surface.

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