Positioning assembly

Abstract

The utility model relates to a positioning assembly which comprises a positioning optical filter, and criss-cross grid scale marks are arranged in the middle of the positioning optical filter. When the positioning optical filter is used, the positioning optical filter is installed on an interface base of a brain-computer interface device. According to the utility model, the positioning assembly is adopted to obtain a blood vessel distribution image, so that the blood vessel distribution under the dura mater is detected, and then the micro-needle assembly is adjusted, so that the multi-micro-needle one-time implantation is carried out by avoiding important blood vessel positions. Therefore, the position needing to avoid the blood vessel is accurately positioned by shooting the image and combining the grid scale marks on the positioning optical filter, so that the microneedle needing to be cut is judged. And then the microneedles at the corresponding positions are cut off, so that the aim of avoiding blood vessels under the dura mater when the microneedle array is integrally implanted is fulfilled, and the damage of the microneedles to brain tissues and the blood vessels is reduced as much as possible.

Description

Technical Field

[0001] This utility model relates to the field of human-computer interaction technology, and in particular to a positioning component. Background Technology

[0002] Brain-computer interface is a technology that enables human-computer interaction by directly reading brain signals and input signals through external devices. It can be applied to medical rehabilitation, neuroscience research, and intelligent control.

[0003] Existing brain-computer interfaces can be mainly divided into invasive brain-computer interfaces and non-invasive brain-computer interfaces.

[0004] Non-invasive brain-computer interfaces (BCIs) refer to technologies that acquire electrical signals from the brain through an electrode array placed on the surface of a biological tissue, such as the scalp, to achieve human-computer interaction without cutting into biological tissues such as the skull or implanting electrodes inside the brain. Compared to invasive BCIs, they are safer, simpler, and easier to operate. However, their signal quality is lower, and they are more susceptible to external interference, leading to more complex signal processing.

[0005] Invasive brain-computer interfaces (BCIs) are technologies that insert electrodes or probes into relevant tissues of a biological organism, such as the cerebral cortex, to obtain neural signals. Compared to non-invasive BCIs, invasive BCIs offer higher signal accuracy and stability, provide better control precision and response speed, and enable more complex motor and interactive tasks.

[0006] Existing invasive brain-computer interface technologies have some drawbacks.

[0007] For example, since blood vessels are distributed in biological tissues such as the subdural space, if they are not avoided during microneedle implantation and cause blood vessel rupture, it can lead to head injury. Currently, the main method is to implant microneedles one by one, which requires the doctor's experience to judge the location of blood vessels and avoid them. However, this method is not accurate in locating blood vessels and is prone to errors. In addition, it is difficult to implant large-scale microneedles at once, which reduces the implantation efficiency. Summary of the Invention

[0008] This utility model provides a positioning component to solve the problem that blood vessel positioning is not accurate in related technologies, and errors are easy to occur during microneedle implantation.

[0009] This utility model embodiment provides a positioning component, the positioning component comprising:

[0010] A positioning filter, wherein the center of the positioning filter is provided with crisscrossing grid lines;

[0011] In use, the positioning filter is installed on the interface base of the brain-computer interface device.

[0012] In some embodiments, the interface base is provided with a through channel, and an inner wall of the through channel is provided with a bottom support; and an inner wall of the interface base is provided with an interface guide part extending axially along the bottom support;

[0013] The side wall of the positioning filter is provided with a filter guide part matched with the interface guide part.

[0014] In some embodiments, the interface guide part is a groove formed by the inner wall of the interface base being recessed, and the filter guide part is a column formed by the side wall of the positioning filter being protruded;

[0015] Alternatively, the interface guide part is a column formed by the inner wall of the interface base being protruded, and the filter guide part is a groove formed by the side wall of the positioning filter being recessed.

[0016] In some embodiments, the positioning assembly further comprises a clamping clamp, and the positioning filter is provided with a first clamping hole matched with the clamping clamp.

[0017] In some embodiments, the first clamping hole is a half counterbore.

[0018] In some embodiments, the material of the positioning filter is polymethyl methacrylate (PMMA), polycarbonate (PC), a multilayer dielectric film, calcium fluoride or magnesium fluoride.

[0019] In some embodiments, the material of the grid scale line is chromium, indium tin oxide, gold or platinum.

[0020] In some embodiments, the etching depth of the grid scale line is 1-3 μm.

[0021] In some embodiments, the line width of the grid scale line is greater than the resolution of a near-infrared imaging system used for image shooting.

[0022] In some embodiments, the positioning assembly further comprises a near-infrared imaging system for image shooting.

[0023] The beneficial effects brought by the technical scheme of the utility model include:

[0024] The utility model adopts the positioning assembly, acquires the blood vessel distribution image, thereby ascertains the blood vessel distribution of the related tissue of organism such as dura mater, and then adjusts the microneedle assembly, thereby avoids important blood vessel position and carries out multiple microneedle disposable implantation.

[0025] It can be seen that by shooting an image, the position of the microneedle that needs to be cut is determined by combining the grid scale line on the positioning filter, so as to avoid blood vessels, and then the microneedle at the corresponding position is cut, so as to avoid blood vessels under the dura mater when the microneedle array is implanted as a whole, and to reduce the damage of the microneedle to the biological tissues such as brain tissue and blood vessels as much as possible. BRIEF DESCRIPTION OF DRAWINGS

[0026] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed in the embodiment description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.

[0027] Figure 1 An exploded view of the brain-computer interface device provided by the embodiments of the present application is shown in the figure.

[0028] Figure 2 An interface base schematic diagram provided by the embodiments of the present application is shown in the figure.

[0029] Figure 3 A sifter schematic diagram provided by the embodiments of the present application is shown in the figure.

[0030] Figure 4 A microneedle assembly schematic diagram provided by the embodiments of the present application is shown in the figure.

[0031] Figure 5 A microneedle base schematic diagram provided by the embodiments of the present application is shown in the figure.

[0032] Figure 6 A microneedle mounting plate schematic diagram provided by the embodiments of the present application is shown in the figure.

[0033] Figure 7 A microneedle mechanism schematic diagram provided by the embodiments of the present application is shown in the figure.

[0034] Figure 8 A microneedle base and microneedle mounting plate assembly schematic diagram provided by the embodiments of the present application is shown in the figure.

[0035] Figure 9 An implantation device schematic diagram provided by the embodiments of the present application is shown in the figure.

[0036] Figure 10 A microneedle array structure schematic diagram provided by the embodiments of the present application is shown in the figure (when torn).

[0037] Figure 11 A microneedle array structure schematic diagram provided by the embodiments of the present application is shown in the figure (when attached).

[0038] Figure 12The barb schematic view is provided for the embodiment of the utility model;

[0039] Figure 13 The schematic view when installing integrated circuit chip is provided for the embodiment of the utility model;

[0040] Figure 14 The fixed structural member schematic view is provided for the embodiment of the utility model;

[0041] Figure 15 The cutting soft needle body electrode schematic view is provided for the embodiment of the utility model;

[0042] Figure 16 The integrated circuit chip reverse welding schematic view is provided for the embodiment of the utility model;

[0043] Figure 17 The installation positioning assembly schematic view is provided for the embodiment of the utility model;

[0044] Figure 18 The positioning assembly schematic view is provided for the embodiment of the utility model;

[0045] Figure 19 The installation screen schematic view is provided for the embodiment of the utility model;

[0046] Figure 20 The installation pre-punching kit schematic view is provided for the embodiment of the utility model;

[0047] Figure 21 The pre-punching kit schematic view is provided for the embodiment of the utility model;

[0048] Figure 22 For Figure 21 Another perspective schematic view;

[0049] Figure 23 Another pre-punching kit schematic view is provided for the embodiment of the utility model;

[0050] Figure 24 The pressing assembly schematic view is provided for the embodiment of the utility model.

[0051] In the drawing:

[0052] 1, interface base; 10, bottom support; 11, interface guide portion; 12, ear seat; 13, top support; 14, top cover; 15, pad high block;

[0053] 2, screen; 20, screen hole; 21, screen guide portion;

[0054] 3, microneedle assembly; 30, microneedle base; 300, microneedle guide hole; 301, microneedle guide part; 302, first installation auxiliary hole; 31, microneedle mechanism; 310, microneedle; 311, microneedle installation plate; 3110, clamping groove; 3111, installation plate guide part; 3112, second installation auxiliary hole; 312, microneedle array structure; 3120, hard needle; 31200, hard needle tail; 31201, hard needle body electrode; 3121, soft needle; 31210, soft needle tail; 31211, soft needle body electrode; 31212, barb; 3122, fixing structure; 313, integrated circuit chip; 314, microstrip line; 315, installation auxiliary assembly; 3150, guide rod; 3151, clamping sleeve; 31510, sleeve; 31511, operation part;

[0055] 4, communication assembly; 40, communication module; 400, communication module guide part; 401, temporary fixing groove; 41, battery;

[0056] 5, implant device; 50, implant plate; 500, second elastic claw; 51, implant rod; 510, first elastic claw; 52, main rod; 53, limiting sleeve; 54, multi-joint arm;

[0057] 6, positioning assembly; 60, positioning filter; 601, filter guide part; 602, first clamping hole; 61, clamping clamp;

[0058] 7, pre-punching kit; 70, needle plate; 700, needle hole; 701, needle plate guide part; 702, second clamping hole; 71, punching needle; 72, pressing plate; 720, punching needle installation hole; 721, pressing plate guide part; 73, pressing rod; 730, connecting rod; 731, connecting plate; 732, pressing part; 74, shell. DETAILED DESCRIPTION

[0059] In order to make the purpose, technical scheme and advantages of the embodiments of the present application more clear, the technical scheme in the embodiments of the present application will be described clearly and completely below in combination with the drawings in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without making creative efforts fall within the scope of protection of the present application.

[0060] Referring to Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 , the embodiments of the present application provide a brain-computer interface device, which comprises an interface base 1, a strainer 2 and a microneedle assembly 3.

[0061] The interface base 1 is provided with a through channel to form a hollow cylinder structure, and the inner wall of the through channel is provided with a bottom support 10 for supporting the subsequent installed parts.

[0062] The comb 2 is installed on the interface base 1 and supported on the bottom support 10, and the middle part of the comb 2 is provided with comb holes 20 arranged in an array as the channel for micro-needle implantation.

[0063] The micro-needle assembly 3 comprises a micro-needle base 30 and a micro-needle mechanism 31, the micro-needle base 30 is installed on the comb 2, and the middle part of the micro-needle base 30 is provided with micro-needle guide holes 300 arranged in an array, and the micro-needle mechanism 31 is installed on the micro-needle base 30, and the micro-needles 310 of the micro-needle mechanism 31 pass through the micro-needle guide holes 300, the comb holes 20 and the through channel of the interface base 1 in sequence.

[0064] The centers of the micro-needle guide holes 300 correspond to the centers of the comb holes 20 one by one, and the hole diameter of the comb holes 20 is larger than the hole diameter of the micro-needle guide holes 300.

[0065] In the brain-computer interface device, the micro-needles 310 pass through the micro-needle guide holes 300, the comb holes 20 and the through channel of the interface base 1 in sequence from top to bottom and then enter the biological tissue such as brain tissue, and since the hole diameter of the comb holes 20 is larger than the hole diameter of the micro-needle guide holes 300, the hole diameters of the layers from bottom to top are gradually reduced. The size of the micro-needles 310 is close to that of the uppermost micro-needle guide hole 300 in design, so that the micro-needle guide hole 300 plays a positioning and guiding role during micro-needle implantation, and the high precision of the implantation position is ensured. Since a certain inclination may be generated during the micro-needle processing, assembly and implantation process, the design scheme of the enlarged lower comb holes 20 is to ensure that the micro-needles generate a small inclination when passing through the implantation channel from top to bottom, and since the hole diameter of the lower layer is larger than that of the upper layer, the extra hole space of the lower layer becomes a buffer area, which plays a buffering role when the micro-needles are inclined, so that the micro-needles are difficult to deform or break due to touching the side wall of the comb holes 20, and the mechanical stability of the micro-needles is improved.

[0066] It can be seen that the design of the gradually enlarged multi-layer hole size from top to bottom ensures the reliability of the micro-needle implantation, and can reduce the implantation position deviation caused by the error in the micro-needle assembly process or implantation angle.

[0067] It can be understood that the material of the interface base 1 can be selected from medical metals or plastics such as stainless steel, titanium, titanium-aluminum-vanadium alloy, nickel-titanium alloy, cobalt-chromium alloy, and polyether ether ketone (PEEK).

[0068] It can be understood that the shape of the interface base 1 can be selected according to actual needs, including but not limited to a circular shape, and preferably a circular shape. Adaptively, the grating 2 and the microneedle base 30 also preferably adopt a circular shape. Adaptively, the bottom support 10 and the top support 13 can form a ring shape.

[0069] It can be understood that, in order to facilitate assembly, prevent the microneedles from being difficult to penetrate due to misalignment, and prevent adverse effects caused by misalignment between parts during subsequent long-term use, as shown in Figure 2 , an interface guide portion 11 extending axially along the bottom support 10 is arranged on the inner wall of the interface base 1; as shown in Figure 3 , a grating guide portion 21 adapted to the interface guide portion 11 is arranged on the side wall of the grating 2; as shown in Figure 5 , a microneedle guide portion 301 adapted to the grating guide portion 21 is arranged on the side wall of the microneedle base 30.

[0070] Specifically, as shown in Figure 2 , the interface guide portion 11 can be a column on the inner wall formed by the inner wall of the interface base 1 protruding; correspondingly, in order to facilitate assembly of subsequent components, as shown in Figure 3 , the grating guide portion 21 is recessed from the side wall of the grating 2 towards the side where the grating hole 20 is located, so that the outer wall of the grating guide portion 21 forms a groove, and the groove is adapted to the interface guide portion 11, and the inner wall of the grating guide portion 21 forms a column; correspondingly, as shown in Figure 5 , the microneedle guide portion 301 is recessed from the side wall of the microneedle base 30 towards the side where the microneedle guide hole 300 is located, so that the outer wall of the microneedle guide portion 301 forms a groove, and the groove is adapted to the column of the grating guide portion 21, and the inner wall of the microneedle guide portion 301 forms a column.

[0071] The interface guide portion 11 can also be a groove formed by the inner wall of the interface base 1 being recessed, at which time the grating guide portion 21 and the microneedle guide portion 301 can be adaptively adjusted.

[0072] As shown in Figure 2As shown, the interface guide portions 11 are at least two, at least one of the interface guide portions 11 is an equal-diameter guide portion along the axial direction of the base 10; at least another of the interface guide portions 11 is a variable-diameter guide portion along the axial direction of the base 10, and the bottom diameter of the interface guide portion 11 is greater than the top diameter. The combination of the two types of interface guide portions takes into account the requirements of high-precision guidance and stable installation, facilitating the alignment and fixation of subsequent component installation.

[0073] The axial direction of each interface guide portion 11 is consistent with the axial direction of the base 10 (or the axial direction of the interface base 1), some of the interface guide portions 11 have consistent outer diameters at each cross section along the axial direction from top to bottom, and some of the interface guide portions 11 have different outer diameters at each cross section from top to bottom, and the outer diameter decreases as it goes up.

[0074] The equal-diameter interface guide portion 11 helps to provide higher guidance accuracy, while the variable-diameter interface guide portion 11 has the following benefits: first, it helps to fix the bottom of the interface guide portion 11, the lower part can provide a larger contact area, making the fixation of the interface guide portion 11 at the bottom more stable and less likely to loosen or displace. A larger diameter also means greater resistance to torsion, which is particularly important when the interface guide portion 11 is subjected to lateral force or torsional force. Second, the lower design can optimize stress distribution and avoid material fatigue or rupture due to excessive local stress, which helps to extend the service life of the interface guide portion 11 during long-term use. Third, it can reduce the overall weight of the interface guide portion 11 while maintaining structural strength. Fourth, it is easy to install and fasten, reducing installation errors and ensuring that the interface guide portion 11 maintains good positioning accuracy during use.

[0075] It can be understood that the equal-diameter interface guide portion 11 described above can be two groups, symmetrically arranged, and similarly, the variable-diameter interface guide portion 11 described above can be two groups, symmetrically arranged.

[0076] Referring to Figure 2 As shown, the interface base 1 is also provided with an ear seat 12, which can appear in pairs. The ear seat 12 is used to provide a fixed point for a bolt to fix the brain-computer interface device on the biological tissue such as the skull.

[0077] Referring to Figure 1 As shown, the interface base 1 is also provided with a top cover 14, which is installed on the interface base 1 after all components are installed, to protect the internal components.

[0078] Referring to Figure 1 and Figure 4As shown, the brain-computer interface device further comprises a communication assembly 4, which comprises a communication module 40 and a battery 41, and the communication module 40 is connected with the battery 41 and the microneedle mechanism 31. By arranging the communication module 40, wireless transmission of the collected signal is realized, the battery 41 provides power to the communication module 40, and the installation position of the battery 41 can be selected as the brain-computer interface in situ implanted in the head, in front of the chest or behind the ear and the like.

[0079] Referring to Figure 6 and Figure 7 As shown, the microneedle mechanism 31 comprises a microneedle mounting plate 311 and a microneedle array structure 312, the microneedle mounting plate 311 can be mounted on the microneedle base 30, the periphery of the microneedle mounting plate 311 can adopt a circular shape matched with the microneedle base 30, or other shapes such as Figure 6 a square in the drawings, the middle part of the microneedle mounting plate 311 is hollow to form a ring shape, and a clamping groove 3110 is formed on the inner wall of the microneedle mounting plate 311; the microneedle array structure 312 is clamped on the clamping groove 3110 to realize the mounting and fixation of the microneedle array structure 312, the microneedle array structure 312 is electrically connected with the communication module 40, and the microneedle array structure 312 has a row of microneedles 310 distributed at intervals.

[0080] In the microneedle mechanism 31 provided by the utility model, a row of microneedles 310 are arranged on the microneedle array structure 312, which can be 4, 8, 16, 32 or more, and each microneedle 310 is arranged to pass through the microneedle guide hole 300 of the microneedle base 30 to enter the related tissue of the organism such as brain tissue, so that the utility model uses the microneedle array to realize the two-way neural signal acquisition and regulation of multiple channels and high throughput.

[0081] In addition, the utility model is implanted in an array, and a plurality of microneedles are implanted at one time, so that the implantation efficiency of the utility model is obviously improved compared with the implantation of one microneedle at a time.

[0082] In order to improve the fixing and mounting effect of the microneedle array structure 312, simplify the structure of parts and reduce the production cost, referring to Figure 6 As shown, the microneedle mounting plate 311 is provided with a plurality of clamping groove groups, each clamping groove group comprises clamping grooves 3110 respectively located on the opposite two inner walls of the microneedle mounting plate 311; and the two ends of the microneedle array structure 312 are clamped on the two clamping grooves 3110 of the clamping groove group. The two ends of the two microneedle array structures 312 are clamped on the two clamping grooves 3110, which can not only ensure the fixing and mounting effect, but also not affect the arrangement of the microneedles 310 in the middle position.

[0083] Referring to Figure 4 and Figure 7As shown, a plurality of card slot groups can be provided, one card slot group corresponding to the installation of one microneedle array structure 312, and each microneedle array structure 312 having a column of microneedles 310, so that the microneedle mechanism 31 can contain multiple rows and columns of microneedles 310.

[0084] As shown in Figure 4 and Figure 7 As shown, the microneedle mechanism 31 further includes an integrated circuit chip 313 and a microstrip line 314; the microneedle array structure 312 is connected to the integrated circuit chip 313, and the microneedle array structure 312 is clamped on the card slot 3110 through the integrated circuit chip 313; the communication module 40 is electrically connected to the integrated circuit chip 313 through the microstrip line 314. Through the built-in digital signal processor, i.e. the integrated circuit chip 313, local digitization can be realized, which is conducive to reducing the transmission loss of neural signals and improving the signal-to-noise ratio.

[0085] In order to facilitate assembly, to prevent the microneedles from being difficult to penetrate due to misalignment, and to prevent misalignment between parts during subsequent long-term use and cause adverse effects, as shown in Figure 5 and Figure 6 As shown, the side wall of the microneedle base 30 is provided with a microneedle guide 301; the side wall of the microneedle mounting plate 311 is provided with a mounting plate guide 3111 matched with the microneedle guide 301.

[0086] The microneedle guide 301 can be recessed from the side wall of the microneedle base 30 towards the side where the microneedle guide hole 300 is located, so that the outer wall of the microneedle guide 301 forms a groove body matched with the column body of the comb guide 21, and the inner wall of the microneedle guide 301 forms a column body, which is matched with the comb guide 21.

[0087] Similarly, the microneedle guide 301 can also be protruded from the side wall of the microneedle base 30 away from the side where the microneedle guide hole 300 is located, so that the inner wall of the microneedle guide 301 forms a groove body, and the mounting plate guide 3111 is protruded from the side wall of the microneedle mounting plate 311 away from the middle, so that the side wall of the mounting plate guide 3111 forms a column body matched with the groove body of the microneedle guide 301.

[0088] In order to facilitate the installation of the microneedle mechanism 31 on the microneedle base 30, as shown in Figure 5As shown, the microneedle guide part 301 is recessed from the side wall of the microneedle base 30 towards the side where the microneedle guide hole 300 is located; the mounting plate guide part 3111 is recessed from the side wall of the microneedle mounting plate 311 towards the middle region of the microneedle mounting plate 311; the first installation auxiliary hole 302 is provided on the microneedle base 30 corresponding to the mounting plate guide part 3111, and the guide rod 3150 is inserted into the first installation auxiliary hole 302 from the mounting plate guide part 3111. Figure 5 As can be seen, the first installation auxiliary hole 302 can actually be provided on the microneedle guide part 301.

[0089] The first installation auxiliary hole 302 is used in cooperation with the installation auxiliary assembly 315.

[0090] Referring to Figure 4 , Figure 6 and Figure 8 As shown, the microneedle mechanism 31 further comprises an installation auxiliary assembly 315, which comprises a sleeve 3151 and a guide rod 3150, one end of which is inserted into the first installation auxiliary hole 302 and the other end is inserted into the mounting plate guide part 3111, the guide rod 3150 can be a screw rod or the like, and the sleeve 3151 is detachably sleeved on the guide rod 3150.

[0091] The first installation auxiliary hole 302 can be provided with multiple around, such as Figure 6 four in the middle.

[0092] During installation, the guide rod 3150 is inserted into the first installation auxiliary hole 302 on the lower microneedle base 30 from the mounting plate guide part 3111, the top of the sleeve 3151 on the guide rod 3150 is pressed against the microneedle mounting plate 311, and the bottom is supported on the microneedle guide part 301, and the microneedle mounting plate 311 and the lower microneedle base 30 can be temporarily connected together through the installation auxiliary assembly 315 around. The installation auxiliary assembly 315 here plays the role of supporting the microneedle mounting plate 311, and when the sleeve 3151 is installed, the microneedle array structure 312 maintains a certain distance from the microneedle base 30, so that the needle tip of the microneedle 310 can just penetrate the microneedle guide hole 300 of the microneedle base 30. When microneedle cutting and microneedle implantation are needed, the microneedle mounting plate 311 can be pulled by the implantation device after the sleeve 3151 is removed, and the microneedle mounting plate 311 is pushed down to move downward along the guide rod 3150 until the microneedle 310 completely penetrates the microneedle guide hole 300, and then the guide rod 3150 can be removed after the mounting plate guide part 3111 around the microneedle mounting plate 311 and the microneedle guide part 301 of the microneedle base 30 are matched and fixed.

[0093] Referring to Figure 4As shown, the sleeve 31510 is provided with an opening along the axial direction thereof, so that the sleeve 31510 is in a C shape. The diameter of the guide rod 3150 is greater than the opening of the sleeve 31510. The sleeve 3151 is pulled out by pulling the operation part 31511 outward, so that the guide rod 3150 props open the opening of the sleeve 31510, thereby pulling out the sleeve 3151.

[0094] In order to facilitate the implantation of the microneedles, as shown in Figure 1 , Figure 6 and Figure 9 , the microneedle mounting plate 311 is further provided with a second mounting auxiliary hole 3112 for connecting the implantation device 5.

[0095] The implantation device 5 comprises an implantation plate 50, the bottom of the implantation plate 50 is provided with a plurality of implantation rods 51 for being inserted into the second mounting auxiliary hole 3112, and the top of the implantation plate 50 is provided with a main rod 52, the main rod 52 is sleeved with a limiting sleeve 53, and the limiting sleeve 53 is provided with a multi-joint arm 54.

[0096] In use, the implantation rod 51 is inserted into the second mounting auxiliary hole 3112 on the microneedle mounting plate 311, the multi-joint arm 54 is fixed at a position such as a surgical bed, the limiting sleeve 53 is ensured to be fixed, the main rod 52 is limited in the horizontal direction by the limiting sleeve 53, and then the main rod 52 is driven to move downward, thereby pushing the microneedle mounting plate 311 to move downward, so as to realize the implantation of the microneedles.

[0097] As shown in Figure 9 , the bottom of the implantation rod 51 is provided with a plurality of first elastic claws 510, and the temporary fixation of the implantation rod 51 and the microneedle mounting plate 311 is realized through the cooperation of the first elastic claws 510.

[0098] Since the microneedle array structure is connected with the communication module 40, in order to prevent the communication module 40 from moving during implantation and affecting implantation, as shown in Figure 4 , the communication module 40 is provided with a temporary fixing groove 401 for being temporarily fixed on the implantation device 5, and as shown in Figure 9 , the bottom of the implantation plate 50 is provided with two second elastic claws 500 arranged oppositely and at intervals, and when the microneedles are implanted, as shown in Figure 1 , the communication module 40 is arranged vertically, so that the two second elastic claws 500 are clamped in the two temporary fixing grooves 401 on the two sides of the communication module 40, thereby achieving the purpose of temporarily fixing the communication module 40.

[0099] After the implantation of the microneedles is completed, in order to prevent the communication module 40 from moving during the subsequent long-term use, as shown in Figure 4As shown, the communication module 40 side wall is provided with a communication module guide part 400 matched with the microneedle guide part 301.

[0100] Since the hard probe can cause a certain degree of mechanical damage in the body related tissue such as brain tissue, resulting in local tissue inflammation and glial cell proliferation and other problems, thereby affecting the signal quality and reducing the long-term stability.

[0101] In order to solve this problem, see Figure 10 And Figure 14 As shown, the microneedle array structure 312 provided by the utility model includes a hard needle 3120 and a soft needle 3121, the soft needle 3121 is fixed on the surface of the hard needle 3120 through a fixing structure 3122, and the fixing structure 3122 is made of biocompatible degradable material; the communication module 40 is connected to the soft needle 3121.

[0102] The utility model adopts the form of hard needle with soft needle, utilizes the characteristics of high hardness of hard needle, and conveniently implants the soft needle together, after the implantation of the soft needle, since the fixing structure 3122 is made of biocompatible degradable material, under the action of the body related tissue such as tissue fluid, the fixing structure 3122 is dissolved, then the hard needle is taken out, only the soft needle is left in the body related tissue such as brain tissue, since the soft needle has low hardness, it is friendly to the body related tissue such as brain tissue, so the utility model realizes minimally invasive implantation, and can effectively avoid the damage caused by the movement of the hard needle in the body related tissue such as brain tissue.

[0103] See Figure 10 As shown, the hard needle 3120 includes a hard needle tail 31200 and at least one hard needle body electrode 31201 formed on the hard needle tail 31200; the soft needle 3121 includes a soft needle tail 31210 and at least one soft needle body electrode 31211 formed on the soft needle tail 31210; the soft needle tail 31210 is fixed with the hard needle tail 31200, mainly temporary fixed by adhesion, and the soft needle body electrode 31211 is fixed with the hard needle body electrode 31201, mainly fixed by biocompatible degradable material; the microneedle 310 includes the soft needle body electrode 31211 and the hard needle body electrode 31201 fixed with each other.

[0104] The preparation method of the microneedle array structure 312 is as follows:

[0105] First step: see Figure 11 As shown, the soft needle 3121 is prepared on the hard needle 3120 by using conventional MEMS process, and at this time, the positional relationship is that the soft needle is attached to the hard needle.

[0106] See Figure 12As shown, the needle tip part of the soft needle body electrode 31211 is provided with a barb 31212, which facilitates the withdrawal of the hard needle and the long-term fixation of the soft needle after implantation.

[0107] Second step: see Figure 10 As shown, the soft needle 3121 is torn off from the soft needle tail 31210 at an angle, and a part of the needle tip part of the soft needle body electrode 31211 is reserved. The purpose is to make the needle tip of the soft needle body electrode 31211 have higher adhesion for temporarily fixing the soft needle and the hard needle, and the soft needle tail 31210 weakens the adhesion to facilitate the withdrawal of the hard needle after implantation.

[0108] Third step: reattach the soft needle 3121 to the hard needle 3120. If the part torn off before cannot be adhered, you can use glue or tape to fix it.

[0109] Fourth step: see Figure 13 As shown, the integrated circuit chip 313 and the soft needle tail 31210 of the soft needle 3121 are reversely welded together, and then the excess part of the soft needle tail 31210 is cut off. At this time, the positional relationship is that the integrated circuit chip 313 is reversely welded on the soft needle, and the hard needle is at the lowermost layer.

[0110] Fifth step: see Figure 14 As shown, the needle tip part of the microneedle array structure 312 is immersed in a degradable biocompatible material to form a fixed structure 3122 for fixation, which can also be realized by a mold coating method. The degradable biocompatible material includes one or more of silk fibroin, spider silk protein, gelatin and PEG.

[0111] Sixth step: see Figure 15 As shown, the part of the needle tip of the soft needle body electrode 31211 that is not torn off is cut off by laser or other methods. Only the part of the soft needle on the hard needle is cut off, and the hard needle is not cut off. The laser path can be set as a curved path to ensure that the cut part has a round corner.

[0112] Seventh step: see Figure 16 As shown, the reverse welding of the microstrip line 314 and the integrated circuit chip 313 is completed, and the excess soft needle at the top is cut off to facilitate the withdrawal of the hard needle later.

[0113] The clamping groove 3110 clamps the integrated circuit chip 313, the integrated circuit chip 313 is reversely welded with the soft needle 3121, and the soft needle 3121 is fixed with the hard needle 3120 by the adhesion of itself and the degradable biocompatible material such as silk fibroin. Therefore, the microneedle array structure 312 can be fixed by clamping the integrated circuit chip 313 through the clamping groove 3110.

[0114] The embodiment of the utility model further provides a kind of installation method of brain-computer interface device, it includes the following steps: interface base 1, sieve 2 and microneedle assembly 3 are sequentially installed.

[0115] Specifically, after the operation has been completed and the target brain region has been exposed at the opening of the organism-related tissue such as the skull, the implantation installation can be performed according to the following steps:

[0116] (1) Referring to FIG. 1, the interface base 1 is temporarily fixed on the organism-related tissue such as the skull using a bolt or a bone screw. Figure 17

[0117] (2) The positioning assembly 6 is installed in the interface base 1, and an image is taken to obtain a vascular distribution image of the organism-related tissue such as the subdural membrane; based on the vascular distribution image, the microneedle assembly 3 is trimmed to cut off the microneedles 310 corresponding to the positions of the blood vessels; and finally, the positioning assembly 6 is removed.

[0118] Since the organism-related tissue such as the subdural membrane is distributed with blood vessels, if the blood vessels are not avoided during the microneedle implantation, the blood vessels will be ruptured, which will cause head injury and the like. At present, the microneedles are implanted one by one, and the blood vessel positions are determined and avoided by combining the experience of doctors. However, this method is not accurate in positioning the blood vessels and is prone to errors, and on the other hand, it is difficult to perform large-scale microneedle implantation at one time, which reduces the implantation efficiency.

[0119] Therefore, the utility model first uses the positioning assembly 6 to obtain a vascular distribution image, so as to determine the vascular distribution of the organism-related tissue such as the subdural membrane, and then adjusts the microneedle assembly 3 to avoid important blood vessel positions for large-scale microneedle implantation at one time.

[0120] Specifically, in the utility model, referring to FIGS. 1, 2 and 3, the positioning assembly 6 comprises a positioning filter 60, and the positioning filter 60 is provided with longitudinal and transverse intersecting grid scale lines in the middle part. The intersection positions of the grids formed by the grid scale lines correspond to the centers of the comb holes 20 and the centers of the microneedle guide holes 300. Figure 17 Figure 18 By taking an image and combining the grid scale lines on the positioning filter 60, the positions of the blood vessels that need to be avoided are accurately positioned, so as to determine the microneedles that need to be trimmed. Then, the microneedles at the corresponding positions are cut off, so as to achieve the purpose of avoiding the blood vessels of the organism-related tissue such as the subdural membrane when the microneedle array is implanted as a whole, and to minimize the damage of the microneedles to the organism-related tissue such as the brain tissue and the blood vessels.

[0121] By taking an image and combining the grid scale lines on the positioning filter 60, the positions of the blood vessels that need to be avoided are accurately positioned, so as to determine the microneedles that need to be trimmed. Then, the microneedles at the corresponding positions are cut off, so as to achieve the purpose of avoiding the blood vessels of the organism-related tissue such as the subdural membrane when the microneedle array is implanted as a whole, and to minimize the damage of the microneedles to the organism-related tissue such as the brain tissue and the blood vessels.

[0122] ​​Near-infrared light (700–2500 nm, short-wave near-infrared 700–1100 nm, long-wave near-infrared 1100–2500 nm) typically falls within the wavelength range of 700–900 nm. Human tissues absorb this light relatively poorly, allowing near-infrared light to penetrate deep into the skin and tissues, forming clear images. This wavelength range is known as the "bio-optical window." Within this range, the spectral absorption characteristics of hemoglobin exhibit significant differences: near-infrared light around 760 nm is highly sensitive to deoxyhemoglobin, while near-infrared light around 850 nm is more sensitive to oxyhemoglobin. Utilizing these wavelength characteristics, near-infrared imaging systems can detect differences in the levels of oxygenated and deoxyhemoglobin in the blood. By using filters and multi-wavelength excitation sources to capture images at different wavelengths, and by analyzing the light absorption characteristics of these images using algorithms, high-contrast vascular images can be generated.

[0123] Understandably, this is for ease of assembly and precise positioning, see [reference needed]. Figure 17 and Figure 18 As shown, the inner wall of the interface base 1 is provided with an interface guide portion 11 extending along the axial direction of the base support 10, and the side wall of the positioning filter 60 is provided with a filter guide portion 601 that is adapted to the interface guide portion 11; by utilizing the cooperation between the filter guide portion 601 and the interface guide portion 11, precise installation and positioning can be achieved.

[0124] It is understood that if the interface guide portion 11 is a groove formed by the recess of the inner wall of the interface base 1, then the filter guide portion 601 is a column formed by the protrusion of the side wall of the positioning filter 60; if the interface guide portion 11 is a column formed by the protrusion of the inner wall of the interface base 1, then the filter guide portion 601 is a groove formed by the recess of the side wall of the positioning filter 60.

[0125] Because the interface base 1 is small, for easy insertion or removal of the positioning filter 60, see [reference needed]. Figure 18 As shown, the positioning component 6 further includes a clamping clip 61, and the positioning filter 60 has a first clamping hole 602 adapted to the clamping clip 61; further, the first clamping holes 602 are arranged in pairs and symmetrically distributed on the positioning filter 60.

[0126] The first gripping hole 602 can be either a through hole or a semi-recessed hole to prevent the legs of the gripper 61 from protruding through the first gripping hole 602 and affecting biological tissues such as brain tissue.

[0127] The material of the positioning filter 60 can be selected from polymethyl methacrylate (PMMA), polycarbonate (PC), multilayer dielectric film, calcium fluoride, magnesium fluoride, and other materials meeting the optical performance requirements.

[0128] The material of the grid scale line is black or dark, which has a high absorption rate in the near-infrared wave band and can form a clear contrast. The grid scale line can be relatively thin. The material can be selected from chromium, indium tin oxide, gold, or platinum.

[0129] The grid scale line on the positioning filter 60 is processed by photolithography or laser etching, thereby obtaining a high-resolution and high-contrast grid pattern.

[0130] If the grid scale line is drawn by etching, the etching depth will also affect the imaging effect. Specifically, the etching depth determines the optical contrast between the grid scale line and the surrounding area. A deeper grid scale line usually produces more obvious optical contrast, making the grid scale line clearer in near-infrared imaging. However, too deep grid scale line can increase optical scattering, weaken the mechanical strength of the filter, and increase the risk of surface damage and cracking, which can affect the quality of blood vessel imaging. The etching depth of the grid scale line is 1-3 μm, which can provide sufficient optical contrast without significantly affecting the overall performance of the filter.

[0131] In actual application, the width of the grid scale line is greater than the resolution of the near-infrared imaging system used for shooting images to ensure that the grid scale line can be clearly identified without affecting the imaging of blood vessels. For example, if the resolution of the imaging system is 50 μm, the width of the grid scale line should be about 75 μm. The specific selection should also be adjusted according to different application requirements.

[0132] The positioning assembly 6 also includes a near-infrared imaging system for shooting images.

[0133] (3) Referring to Figure 19 The grate 2 is installed.

[0134] (4) Due to the presence of the dura mater, the existing solution is to choose to uncover the biological tissue related to the site where the microneedle array needs to be implanted, such as the dura mater, for implantation. Although this method can successfully implant the microneedle, it is complex and inconvenient to operate because the biological tissue related to the site where the microneedle array needs to be implanted, such as the dura mater, needs to be uncovered. Since the entire biological tissue related to the site where the microneedle array needs to be implanted, such as the dura mater, is uncovered, it may affect blood vessels and other structures. At the same time, after all, a piece of biological tissue related to the site where the microneedle array needs to be implanted, such as the dura mater, is uncovered, there may be a lot of damage to the entire biological tissue related to the site where the microneedle array needs to be implanted, such as the dura mater.

[0135] In order to simplify the operation, reduce the damage degree to the organism related tissue such as the dura mater, the utility model provides a pre-punching kit 7 to only perform the punching operation on the position of the organism related tissue such as the dura mater which needs to implant the microneedle, and does not need to perform the organism related tissue such as the dura mater uncovering treatment.

[0136] Specifically, referring to Figure 20 As shown in the drawings, the pre-punching kit 7 is installed on the grating 2, and based on the blood vessel distribution image, the pre-punching kit 7 is used to punch the organism related tissue such as the dura mater by avoiding the blood vessels; after the punching is completed, the pre-punching kit 7 is removed.

[0137] Among them, referring to Figure 21 、 Figure 22 、 Figure 23 、 Figure 24 As shown in the drawings, the pre-punching kit 7 comprises a needle plate 70, a needle assembly and a pressing assembly, the needle plate 70 is provided with a needle hole 700 corresponding to the center position of the grating hole 20 of the grating 2 in the middle; the needle assembly comprises a plurality of punching needles 71; the pressing assembly comprises a pressing plate 72 for pressing the punching needle 71 downward, and a pressing rod 73 connected to one end of the pressing plate 72.

[0138] The punching needle 71 is arranged according to the blood vessel distribution map, and then the pressing rod 73 is pressed to drive the pressing plate 72 to move downward, so that the plurality of punching needles 71 are punched into the organism related tissue such as the dura mater through the needle hole 700. After the punching is completed, the pre-punching kit 7 is taken out.

[0139] Since the depth of the punching needle 71 inserted into different organism related tissues such as the brain may be different, in order to adapt to different insertion depths, the utility model embodiment provides a plurality of schemes.

[0140] For example, as an example, referring to Figure 21 、 Figure 22 As shown in the drawings, the pressing assembly further comprises a sleeve 74, the pressing plate 72 is located in the sleeve 74, the diameter of the circumscribed circle of the pressing plate 72 is smaller than the diameter of the inscribed circle of the sleeve 74, the pressing rod 73 is screw connected with the sleeve 74 to adjust the position of the pressing plate 72 in the sleeve 74; the outer wall of the pressing rod 73 is further provided with a scale line.

[0141] All the punching needles 71 are inserted into the needle hole 700, the position of the pressing plate 72 in the sleeve 74 is adjusted by rotating the pressing rod 73, the position of the pressing plate 72 is identified by the scale line, so that the required insertion depth is adjusted, and after the adjustment, the pressing is performed to make the whole pressing assembly move downward until it abuts against the needle plate 70, and the punching is realized.

[0142] It can be understood that the above-mentioned pressing assembly can press all the microneedles at one time to punch, or can press in batches to punch. For example, referring toFigure 21 As shown in FIG. 1, the size of the pressing plate 72 is configured to cover a portion of the needle holes 700 on the needle plate 70, at which time the batched, arrayed multiple microneedles can be pressed down together to punch. For example, the size of the pressing plate 72 is configured to cover all the needle holes 700 on the needle plate 70, at which time the one-time pressing can be realized, and the shell guiding portion (not shown in the figure) that is adapted to the sieve guiding portion 21 can be arranged on the side wall of the shell 74. For example, if the sieve guiding portion 21 is recessed from the side wall of the sieve 2 towards the side where the sieve hole 20 is located, so that the outer wall of the sieve guiding portion 21 forms a groove that is adapted to the interface guiding portion 11, and the inner wall of the sieve guiding portion 21 forms a column, then the shell guiding portion is recessed from the side wall of the shell 74 to form a groove that is adapted to the column; similarly, if the sieve guiding portion 21 is protruded, the shell guiding portion is adjusted accordingly.

[0143] For example, as shown in FIG. 1, Figure 23 and Figure 24 As shown in FIG. 1, the bottom of the pressing plate 72 is provided with arrayed punching needle mounting holes 720, and the punching needle 71 is inserted into the punching needle mounting hole 720 during punching; the pressing rod 73 includes connecting rods 730, a connecting plate 731, and a pressing portion 732, one end of the plurality of connecting rods 730 is connected to the periphery of the pressing plate 72, and the other end is connected to the periphery of the connecting plate 731, and the pressing portion 732 is mounted on the connecting plate 731.

[0144] By pressing the pressing portion 732 downward, the pressing rod 73 as a whole drives the punching needle 71 to punch into the dura mater through the needle hole 700 until the pressing plate 72 abuts against the needle plate 70.

[0145] In order to adapt to different penetration depths, the needle assembly has multiple different specifications, which are distinguished by the length of the punching needle 71, and the lengths of the punching needles 71 of each needle assembly are different; according to the required punching depth, the punching needle 71 with the appropriate length is selected to be inserted into the punching needle mounting hole 720.

[0146] Alternatively, the connecting rods 730 and the pressing plate 72 are detachably connected, for example, by using commonly used insertion, clamping, etc., and the pressing plate 72 has multiple different specifications, which are distinguished by the hole depth of the punching needle mounting hole 720, and the hole depths of the punching needle mounting holes 720 of each pressing plate 72 are different; according to the required punching depth, the pressing plate 72 with the appropriate length is selected to be inserted into the punching needle 71.

[0147] It can be understood that the above pressing assembly can punch all the microneedles at one time or in batches. For example, the size of the pressing plate 72 is configured to cover a portion of the needle holes 700 on the needle plate 70, at which time the batched, arrayed multiple microneedles can be pressed down together to punch. For example, as shown in FIG. 1,Figure 23 As shown in the figure, the size of the pressing plate 72 is configured to cover all the needle holes 700 on the needle plate 70, so that one-time punching can be realized. Further, the side wall of the grating 2 is provided with a grating guide part 21, and the side wall of the pressing plate 72 is provided with a pressing plate guide part 721 matched with the grating guide part 21.

[0148] In order to facilitate installation and positioning, referring to Figure 21 As shown in the figure, the side wall of the needle plate 70 is provided with a needle plate guide part 701 matched with the grating guide part 21.

[0149] For example, if the grating guide part 21 is recessed from the side wall of the grating 2 towards the grating hole 20, so that the outer wall of the grating guide part 21 forms a groove matched with the interface guide part 11, and the inner wall of the grating guide part 21 forms a column, the pressing plate guide part 721 is recessed from the side wall of the pressing plate 72 to form a groove matched with the column, and the needle plate guide part 701 is recessed from the side wall of the needle plate 70 to form a groove matched with the column. Similarly, if the grating guide part 21 is protruded, the pressing plate guide part 721 and the needle plate guide part 701 are adjusted adaptively.

[0150] In the utility model, the material of the punching needle 71 is selected from stainless steel, titanium alloy or tungsten; the material of the needle plate 70 is selected from stainless steel, titanium, titanium-aluminum-vanadium alloy, nickel-titanium alloy, cobalt-chromium alloy or polyether ether ketone PEEK.

[0151] Since the interface base 1 is small, in order to facilitate the insertion or removal of the needle plate 70, referring to Figure 21 As shown in the figure, the needle plate 70 is provided with a second clamping hole 702 matched with the clamping clamp 61 of the positioning assembly 6. Further, the above-mentioned second clamping holes 702 are two by two to form a pair, and are symmetrically distributed on the needle plate 70.

[0152] (5) After completing the punching, the microneedle assembly 3 is installed on the grating.

[0153] Specifically, referring to Figure 1 , Figure 4 , Figure 5 , Figure 6 , Figure 7 and Figure 9As shown, first install the microneedle base 30. In the use of the implant device 5 to pull and fix the microneedle array structure 312 and the communication module 40, the other end of the implant device 5 should be fixed on the second installation auxiliary hole 3112 of the microneedle installation plate 311, so that the microneedle tip is aligned with the grid hole 20 of the grid below. Then remove the sleeve 3151, and use the implant device 5 to slowly move the microneedle array structure 312 as a whole along the guide rod 3150 downward, and stop when the microneedle is implanted to the predetermined depth. Then release the temporary fixation of the interface base 1, and at this time, use the implant device 5 to keep the height position of the microneedle installation plate 311 unchanged, and simultaneously lift the interface base 1, the grid 2 and the microneedle base 30 upward until the microneedle installation plate 311 is stably nested in the microneedle base 30.

[0154] Remove the guide rod 3150, and use the cushion block 15 to temporarily support around the outer ring of the interface base 1, as shown. Figure 1

[0155] After waiting for the biorelated tissue such as tissue fluid to dissolve the biodegradable biocompatible material used for temporarily fixing the connection between the soft needle and the hard needle, the hard needle is removed, and at this time, the soft needle is left in the biorelated tissue such as the brain tissue under the dura mater, fixing the communication module 40 and the battery 41. Remove the cushion block 15, and install the lifted interface base 1, the grid 2, the microneedle base 30 and the microneedle installation plate 311 downward to the position, and at this time, the soft needle leaves a certain redundant part to avoid the displacement of the biorelated tissue such as the brain tissue movement to pull the soft needle and cause certain damage to the brain tissue or the soft needle. Then pour glue for packaging and protection of the circuit, and fix by using bolts or bone screws. Install the top cover 14, and then suture the scalp.

[0156] In summary, the utility model integrates multiple microneedles for one-time implantation, which greatly improves the implantation efficiency compared with the traditional method of sequentially implanting single electrodes.

[0157] The utility model realizes minimally invasive implantation and effectively avoids the damage caused by the hard microneedle electrode to the biorelated tissue such as the brain tissue of the patient during movement. The use of the flexible microneedle electrode can avoid the displacement and mutual shearing between the brain tissue and the electrode caused by the mechanical performance matching the brain tissue after intracranial implantation, so that the same neuron activity can be tracked for a long time.

[0158] The utility model has higher single device channel number, and multiple detection sites are distributed in the longitudinal direction of the electrode, which can simultaneously record single neuron signal Spike and local field potential LFP, can collect three-dimensional high-density brain electrical signals, and promotes precise and smooth thought-controlled movement, realizes high-throughput acquisition and regulation of bidirectional neural signals.

[0159] ​Built-in integrated circuit chips enable local digitization, which helps reduce the transmission loss of neural signals and improve the signal-to-noise ratio.

[0160] The high throughput, bidirectional communication, minimally invasive implantation, and low damage during use of the overall brain-computer interface device ensure long-term stability after implantation, making the brain-computer interface implantation process more efficient, safe, and controllable.

[0161] The above description is merely a specific embodiment of the present invention, enabling those skilled in the art to understand or implement the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features claimed herein.

Claims

1. A positioning assembly, characterized by The positioning assembly (6) comprises: a positioning filter (60) provided with longitudinal and transverse grid scale lines in the middle part; In use, the positioning filter (60) is installed on the interface base (1) of the brain-computer interface device.

2. The positioning assembly according to claim 1, wherein: the interface base (1) is provided with a through channel, and the inner wall of the through channel is provided with a bottom support (10); the inner wall of the interface base (1) is provided with an interface guide portion (11) extending axially along the bottom support (10); the side wall of the positioning filter (60) is provided with a filter guide portion (601) matched with the interface guide portion (11).

3. The positioning assembly according to claim 2, wherein: the interface guide portion (11) is a groove formed by the inner wall of the interface base (1) being recessed, and the filter guide portion (601) is a column formed by the side wall of the positioning filter (60) being protruded; or the interface guide portion (11) is a column formed by the inner wall of the interface base (1) being protruded, and the filter guide portion (601) is a groove formed by the side wall of the positioning filter (60) being recessed.

4. The positioning assembly according to claim 1, wherein: the positioning assembly (6) further comprises a clamping clip (61), and the positioning filter (60) is provided with a first clamping hole (602) matched with the clamping clip (61).

5. The positioning assembly according to claim 4, wherein: the first clamping hole (602) is a half counterbore.

6. The positioning assembly according to claim 1, wherein: the material of the positioning filter (60) is polymethyl methacrylate (PMMA), polycarbonate (PC), a multilayer dielectric film, calcium fluoride or magnesium fluoride.

7. The positioning assembly according to claim 1, wherein: the material of the grid scale lines is chromium, indium tin oxide, gold or platinum.

8. The positioning assembly according to claim 1, wherein: the etching depth of the grid scale lines is 1-3 μm.

9. The positioning assembly according to claim 1, wherein: the line width of the grid scale lines is greater than the resolution of a near-infrared imaging system used for image shooting.

10. The positioning assembly according to claim 1, wherein: the positioning assembly (6) further comprises a near-infrared imaging system for image shooting. ​

Images