Device for decoloring valaciclovir hydrochloride

Abstract

The utility model relates to the technical field of medicine manufacturing, and discloses a device for decoloring valaciclovir hydrochloride, which comprises a fixed seat and a decoloring tank, an outer heat insulation shell is arranged on the inner side wall of the fixed seat, and the top end of the outer heat insulation shell is fixedly connected with a tank cover. According to the valaciclovir hydrochloride decoloring device, activated carbon powder is fed into the decoloring tank through the carbon powder feeding pipe, and the stirring blades are driven by the stirring motor to fully stir a valaciclovir hydrochloride solution in the decoloring tank, so that the valaciclovir hydrochloride solution is in full contact with the activated carbon powder, impurities are promoted to be adsorbed by the activated carbon powder, and the decoloring effect is improved; meanwhile, the scraping plate mounted on the rotating rod can be used for scraping the solution on the tank wall, so that the completeness of the decoloring of the valaciclovir hydrochloride solution is guaranteed, and meanwhile, the decolored solution can be subjected to carbon-liquid separation through the plurality of filter plates mounted in the filter tank, so that the clear valaciclovir hydrochloride solution can be obtained.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of medicine manufacturing, especially relates to a device for valaciclovir hydrochloride decolorization. BACKGROUND

[0002] Valaciclovir hydrochloride is an antiviral drug, which is widely used in clinical treatment. In the production process, the valaciclovir hydrochloride solution may contain impurities, which affects the quality and efficacy of the drug. Therefore, the valaciclovir hydrochloride solution needs to be decolorized to remove the impurities.

[0003] After searching, the Chinese patent publication No. CN204848709U discloses a device for valaciclovir hydrochloride decolorization, which is composed of a reaction kettle and an activated carbon decolorization column connected with the reaction kettle. The reaction kettle and the activated carbon decolorization column are connected through pipelines, pumps and valves to form a circulating loop. The device solves the problem of valaciclovir hydrochloride decolorization in the production of valaciclovir hydrochloride, and is suitable for valaciclovir hydrochloride decolorization operation. The device has the characteristics of simple operation, high decolorization efficiency, good decolorization effect and easy popularization.

[0004] The above device connects the reaction kettle and the activated carbon decolorization column through pipelines, pumps and valves to form a circulating loop, thereby solving the problem of valaciclovir hydrochloride decolorization in the production of valaciclovir hydrochloride. However, the activated carbon decolorization column used in the device cannot fully filter and decolorize the valaciclovir hydrochloride solution during operation, and the filtered impurities will accumulate on the surface of the activated carbon decolorization column, causing the decolorization performance of the activated carbon decolorization column to decrease. Therefore, a device for valaciclovir hydrochloride decolorization is proposed to solve the above problems. UTILITY MODEL CONTENTS

[0005] To make up for the above shortcomings, the utility model provides a device for valaciclovir hydrochloride decolorization, which aims to improve the problem that the activated carbon decolorization column used in the device cannot fully filter and decolorize the valaciclovir hydrochloride solution during operation, and the filtered impurities will accumulate on the surface of the activated carbon decolorization column, causing the decolorization performance of the activated carbon decolorization column to decrease.

[0006] In order to achieve the above object, the utility model discloses the following technical scheme: a device for the discoloration of valaciclovir hydrochloride, including fixed seat and decoloring jar, the inner side wall of fixed seat is provided with the outer thermal -insulated shell, the top of outer thermal -insulated shell is fixedly connected with jar cover, the top middle part of jar cover is fixedly connected with stirring motor, the output of stirring motor is fixedly connected with the rotating rod, the middle part of rotating rod is fixedly connected with a plurality of evenly distributed stirring vane, the middle part upper end of rotating rod is fixedly connected with scraper, the middle right -hand member of jar cover is fixedly connected with carbon powder feeding pipe, the right side bottom of decoloring jar is communicated with the flow guide pipe, the other end of flow guide pipe is fixedly connected with filter jar, the inner side wall of filter jar is fixedly connected with a plurality of evenly distributed fixed clamping plate, the adjacent side of a plurality of fixed clamping plate is slidably connected with filter plate, and the bottom of decoloring jar is provided with heating assembly.

[0007] As further description of the above technical solution:

[0008] The heating assembly includes a heating disc, which is arranged at the bottom end of the decoloring jar, and two ceramic fixing rings are arranged at the top end of the heating disc, a plurality of evenly distributed heat conducting rods are fixedly connected to the middle part of the two ceramic fixing rings, and the bottom ends of the plurality of heat conducting rods are fixedly connected to the top middle part outside of the heating disc.

[0009] As further description of the above technical solution:

[0010] The top end of the filter jar is hingedly connected with a sealing plate, and the right end of the filter jar is communicated with a discharge pipe.

[0011] As further description of the above technical solution:

[0012] The middle part of the flow guide pipe is fixedly connected with a flow limiting valve, and the middle left end of the jar cover is fixedly connected with a feed hopper.

[0013] As further description of the above technical solution:

[0014] The inner side wall of the feed hopper is fixedly connected with a support plate, and the top end of the support plate is provided with ion exchange resin.

[0015] As further description of the above technical solution:

[0016] The front end of the outer thermal -insulated shell is fixedly connected with a data display, and the front middle part of the outer thermal -insulated shell is fixedly connected with a control panel.

[0017] The utility model has the following beneficial effects:

[0018] 1. The utility model discloses a carbon powder feeding pipe is used for putting active carbon powder into the decoloring jar, and then the stirring motor drives the stirring blade to fully stir the valaciclovir hydrochloride solution in the decoloring jar, so that the valaciclovir hydrochloride solution fully contacts with the active carbon powder, thereby promoting the impurities to be adsorbed by the active carbon powder, improving the decoloring effect, and the scraper installed on the rotating rod can scrape the solution on the jar wall, guaranteeing the integrity of the valaciclovir hydrochloride solution participating in the decoloring, and the multiple filter plates installed in the filter jar can separate the carbon liquid after the decoloring is completed, so that the relatively clear valaciclovir hydrochloride solution can be obtained.

[0019] 2. The utility model discloses a heating disc is installed at the bottom end of the decoloring jar, and the heat rod is installed around the decoloring jar, so that the heat rod can uniformly heat the decoloring jar, thereby improving the speed of the valaciclovir hydrochloride solution decoloring and accelerating the production efficiency. DRAWINGS

[0020] Figure 1 A perspective view of a device for valaciclovir hydrochloride decoloring is provided for the utility model;

[0021] Figure 2 An internal structure display drawing of the external thermal insulation shell of the device for valaciclovir hydrochloride decoloring is provided for the utility model;

[0022] Figure 3 A sectional view of the decoloring jar of the device for valaciclovir hydrochloride decoloring is provided for the utility model;

[0023] Figure 4 A schematic view of the filter plate of the device for valaciclovir hydrochloride decoloring is provided for the utility model.

[0024] Legend:

[0025] 1, fixed seat, 2, external thermal insulation shell, 3, decoloring jar, 4, jar cover, 5, stirring motor, 6, rotating rod, 7, stirring blade, 8, scraper, 9, heating assembly, 901, heating disc, 902, heat rod, 903, ceramic fixed ring, 10, carbon powder feeding pipe, 11, flow guide pipe, 12, filter jar, 13, fixed clamping plate, 14, filter plate, 15, sealing plate, 16, discharge pipe, 17, flow limiting valve, 18, feeding hopper, 19, support plate, 20, ion exchange resin, 21, data display, 22, control panel. DETAILED DESCRIPTION

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0027] Reference Figure 1 , Figure 3 and Figure 4 This utility model provides an embodiment of an apparatus for decolorizing valacyclovir hydrochloride, comprising a fixed base 1 and a decolorizing tank 3. An outer insulation shell 2 is provided on the inner side wall of the fixed base 1. A tank cover 4 is fixedly connected to the top of the outer insulation shell 2. A stirring motor 5 is fixedly connected to the middle of the top of the tank cover 4. A rotating rod 6 is fixedly connected to the output end of the stirring motor 5. Multiple evenly distributed stirring blades 7 are fixedly connected to the middle of the rotating rod 6. A scraper 8 is fixedly connected to the upper middle part of the rotating rod 6. A carbon powder feeding pipe 10 is fixedly connected to the right middle part of the tank cover 4. The decolorizing tank 3... The bottom right side of the decolorizing tank 3 is connected to a guide pipe 11, and the other end of the guide pipe 11 is fixedly connected to a filter tank 12. Multiple evenly distributed fixing plates 13 are fixedly connected to the inner side wall of the filter tank 12. Filter plates 14 are slidably connected to adjacent sides of the multiple fixing plates 13. A heating component 9 is provided at the bottom of the decolorizing tank 3. A sealing plate 15 is hinged to the top of the filter tank 12. A discharge pipe 16 is connected to the right end of the filter tank 12. A data display 21 is fixedly connected to the front end of the outer insulation shell 2. A control panel 22 is fixedly connected to the middle of the front end of the outer insulation shell 2.

[0028] Specifically: The data display 21 fixed at the front end of the outer insulation shell 2 can display the heating temperature inside the decolorization tank 3 in real time. At the same time, the operating parameters of the equipment can be adjusted through the control panel 22 fixed at the middle of the front end of the outer insulation shell 2, so as to achieve precise control of the equipment.

[0029] Reference Figure 2 The heating component 9 includes a heating plate 901, which is located at the bottom of the decolorization tank 3. Two ceramic fixing rings 903 are provided at the top of the heating plate 901. Multiple evenly distributed heat-conducting rods 902 are fixedly connected to the middle of the two ceramic fixing rings 903. The bottom ends of the multiple heat-conducting rods 902 all pass through the middle of the ceramic fixing rings 903 and are fixedly connected to the outer side of the top middle of the heating plate 901.

[0030] Specifically: By installing multiple evenly distributed heat-conducting rods 902 on the heating plate 901, the decolorizing tank 3 can be heated evenly, thereby accelerating the decolorization speed. The ceramic fixing rings 903 installed on the heat-conducting rods 902 can limit the heat-conducting rods 902 and prevent them from colliding with each other and causing damage.

[0031] Referring to Figure 1 The middle part of the flow guide pipe 11 is fixedly connected with a flow limiting valve 17, and the middle part of the left end of the tank cover 4 is fixedly connected with a feeding hopper 18; the inner side wall of the feeding hopper 18 is fixedly connected with a support plate 19, and the top end of the support plate 19 is provided with ion exchange resin 20.

[0032] Specifically, the ion exchange resin 20 arranged at the top end of the support plate 19 fixedly connected with the inner side wall of the feeding hopper 18 can preliminarily filter the valaciclovir hydrochloride solution and remove large-particle impurities.

[0033] Working principle: when the user needs to use the device, the valaciclovir hydrochloride solution is added into the decolorizing tank 3 through the feeding hopper 18 fixedly connected with the middle part of the left end of the tank cover 4, and the ion exchange resin 20 arranged at the top end of the support plate 19 fixedly connected with the inner side wall of the feeding hopper 18 can preliminarily filter the valaciclovir hydrochloride solution and remove large-particle impurities, then the activated carbon powder is put into the decolorizing tank 3 through the carbon powder feeding pipe 10, and the valaciclovir hydrochloride solution in the decolorizing tank 3 is fully stirred by the stirring motor 5 driving the stirring blade 7, so that the valaciclovir hydrochloride solution fully contacts with the activated carbon powder, thereby promoting the impurities to be adsorbed by the activated carbon powder and improving the decolorizing effect, and the scraper 8 installed on the rotating rod 6 can scrape the solution on the tank wall, so as to guarantee the completeness of the valaciclovir hydrochloride solution participating in the decolorizing, and the carbon liquid separation of the solution after the decolorizing can be carried out through the multiple filter plates 14 installed in the filter tank 12, so that the relatively clear valaciclovir hydrochloride solution can be obtained.

[0034] Meanwhile, the heating disc 901 is installed at the bottom end of the decolorizing tank 3, and the heat-conducting rod 902 is installed around the decolorizing tank 3, so that the heat-conducting rod 902 can uniformly heat the decolorizing tank 3, thereby improving the speed of the valaciclovir hydrochloride solution decolorizing and effectively accelerating the production efficiency.

[0035] Finally, it should be noted that the above description is only preferred embodiments of the present application and is not intended to limit the present application, although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments or equivalently replace some technical features, and any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.

Claims

1. A device for decolorizing valaciclovir hydrochloride comprising a fixed base (1) and a decolorizing tank (3), characterized in that: The inner side wall of the fixed seat (1) is provided with an external thermal insulation shell (2), the top end of the external thermal insulation shell (2) is fixedly connected with a tank cover (4), the top end of the tank cover (4) is fixedly connected with a stirring motor (5), the output end of the stirring motor (5) is fixedly connected with a rotating rod (6), the middle part of the rotating rod (6) is fixedly connected with a plurality of uniformly distributed stirring blades (7), the middle part of the rotating rod (6) is fixedly connected with a scraper (8), the middle right end of the tank cover (4) is fixedly connected with a carbon powder feeding pipe (10), the right side bottom end of the decolorizing tank (3) is communicated with a flow guide pipe (11), the other end of the flow guide pipe (11) is fixedly connected with a filter tank (12), the inner side wall of the filter tank (12) is fixedly connected with a plurality of uniformly distributed fixed clamping plates (13), the adjacent side of the plurality of fixed clamping plates (13) is slidably connected with a filter plate (14), and the bottom end of the decolorizing tank (3) is provided with a heating assembly (9).

2. A device for decolorizing valaciclovir hydrochloride according to claim 1, characterized in that: The heating assembly (9) comprises a heating disc (901), the heating disc (901) is arranged at the bottom end of the decolorizing tank (3), the top end of the heating disc (901) is provided with two ceramic fixing rings (903), the middle part of the two ceramic fixing rings (903) is fixedly connected with a plurality of uniformly distributed heat conducting rods (902), and the bottom end of the plurality of heat conducting rods (902) is fixedly connected to the top end of the heating disc (901) outside the middle part of the ceramic fixing ring (903).

3. A device for decolorizing valaciclovir hydrochloride according to claim 1, characterized in that: The top end of the filter tank (12) is hingedly connected with a sealing plate (15), and the right end of the filter tank (12) is communicated with a discharge pipe (16).

4. A device for decolorizing valaciclovir hydrochloride according to claim 1, characterized in that: The middle part of the flow guide pipe (11) is fixedly connected with a flow limiting valve (17), and the middle left end of the tank cover (4) is fixedly connected with a feeding hopper (18).

5. A device for decolorizing valaciclovir hydrochloride according to claim 4, characterized in that: The inner side wall of the feeding hopper (18) is fixedly connected with a support plate (19), and the top end of the support plate (19) is provided with ion exchange resin (20).

6. A device for decolorizing valaciclovir hydrochloride according to claim 1, characterized in that: The front end of the external thermal insulation shell (2) is fixedly connected with a data display (21), and the front end of the external thermal insulation shell (2) is fixedly connected with a control panel (22).

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