NK cell immunodetection kit

Abstract

The utility model belongs to the technical field of detection kits, and particularly relates to an NK (Natural Killer) cell immunodetection kit, aiming at the problem that the existing reagent tube clamping efficiency is lower, the following scheme is provided: the NK cell immunodetection kit comprises a kit body, a cover plate is movably connected to one side of the outer wall of the kit body, and a partition plate is fixedly arranged in the kit body; a reagent tube is inserted into the cylindrical air bag through the limiting hole and penetrates through the bearing block for preliminary limiting, the situation of collision during transportation is avoided through the rubber gasket, and when the box body and the cover plate are closed, the abutting block is inserted into the containing cavity and presses the stress air bag tightly, so that the reagent tube is separated from the bearing block. Gas is conveyed through the conveying gas bag and is filled into the cylindrical gas bag, so that the reagent tubes are supported and limited, mutual collision is avoided, the protection effect is achieved, meanwhile, the trouble that manual multiple adjustment and clamping are troublesome is avoided, and the kit body can be directly closed after the reagent tubes are rapidly placed; the clamping time is saved, and the influence of temperature and oxidation due to excessive exposure time of the reagent tube and air is avoided.

Description

TECHNICAL FIELD

[0001] The utility model relates to a detection kit, specifically NK cell immunity detection kit belongs to detection kit technical field. BACKGROUND

[0002] NK cell immunity detection kit is used for detecting natural killer cell (NK cell) related index a kind of kit, utilize flow cytometer to analyze cell one by one, through specific antibody marking NK cell surface marker, such as CD3-CD16+CD56+, to identify and detect NK cell, is used for the immune function evaluation of tumor patient, immunodeficiency disease patient etc. in clinic;It is used for studying the change and mechanism of action of NK cell in the development process of various diseases in scientific research.

[0003] In the prior art, such as the NK cell immunity detection kit with good sealing property disclosed in the announcement No. CN219313385U, the user can clamp and fix the NK cell immunity detection reagent tube after sampling through the test tube clamp, so as to facilitate the user to place the test tube and facilitate use.

[0004] However, in the implementation of the related technology, it is found that the above-mentioned NK cell immunity detection kit with good sealing property has the following problems: although the prior art can achieve good sealing property, during use, especially when the reagent tube after sampling is clamped and fixed, this fixing method needs to be clamped or disassembled one by one by the staff, thereby affecting the actual placement time, which may cause the reagent kit and reagent to be exposed to air too much, which will be affected by temperature and oxidation, and at the same time, it will also affect the convenience of actual taking. In view of this, an NK cell immunity detection kit is provided to overcome the above-mentioned defects. UTILITY MODEL CONTENTS

[0005] The utility model provides an NK cell immunity detection kit to solve the problem that the above-mentioned fixing method needs to be clamped or disassembled one by one by the staff, thereby affecting the actual placement time, which may cause the reagent kit and reagent to be exposed to air too much, which will be affected by temperature and oxidation, and at the same time, it will also affect the convenience of actual taking.

[0006] The utility model realizes the above-mentioned purpose through the following technical scheme: an NK cell immunity detection kit, comprising a box body, a cover plate movably connected to one side of the outer wall of the box body, a partition plate fixedly installed inside the box body, a reagent cavity provided on one side of the partition plate, and a storage mechanism provided on the other side of the partition plate.

[0007] The accommodating mechanism comprises a placement cavity arranged on the other side of the partition plate, a stress air bag embedded in the placement cavity, a conveying air bag connected to one end of the stress air bag penetrating into the reagent cavity, and a cylindrical air bag connected to one end of the conveying air bag, and a resisting block fixedly installed on the outer wall of the cover plate corresponding to the position of the placement cavity, and a limiting hole is formed in the cylindrical air bag.

[0008] As a further scheme of the utility model, a bearing block is fixedly installed inside the reagent cavity, and a rubber gasket is connected to the inside of the bearing block.

[0009] As a further scheme of the utility model, the stress air bag is communicated with the conveying air bag, and the conveying air bag is communicated with the cylindrical air bag.

[0010] As a further scheme of the utility model, grooves are formed in both sides of the inside of the reagent cavity, and an isolation plate is slidably connected to the inside of the grooves.

[0011] As a further scheme of the utility model, a resisting mechanism is arranged on one side of the cover plate, the resisting mechanism comprises a penetrating plate penetrating out of the outer wall of the cover plate, a fixed rod is rotatably connected to the inside of the penetrating plate, and a sleeve is arranged on the end of the fixed rod away from the penetrating plate.

[0012] As a further scheme of the utility model, a damping spring is embedded on the other side of the outer wall of the penetrating plate, and a rubber plate is fixed to one end of the damping spring.

[0013] As a further scheme of the utility model, the sleeve is threadedly connected with the cover plate, and a sliding structure is formed between the cover plate and the penetrating plate.

[0014] The utility model has the advantages that first, the reagent tube is inserted into the cylindrical air bag through the limiting hole, and is preliminarily limited by penetrating into the bearing block, and the rubber gasket is used to avoid the bumping during conveying, when the box body and the cover plate are closed, the resisting block is inserted into the placement cavity and presses the stress air bag, the gas is conveyed through the conveying air bag and filled into the cylindrical air bag, so that the reagent tube is supported and limited, the protection effect is achieved, and the manual multiple adjustment and clamping are avoided, the reagent tube can be quickly placed, the box body can be directly closed, the clamping time is saved, the reagent tube and the air are prevented from being exposed for too long to be affected by the temperature and oxidation.

[0015] The isolation plate is inserted through the sliding groove, the through hole is sleeved outside the reagent tube, and the tube opening is higher than the isolation plate, which can play a preliminary limiting effect before the reagent tube is inserted into the cylindrical cavity, and after the box body and the cover plate are closed, the rubber plate is pressed against the tube opening of the reagent tube under the driving of the penetrating plate and through the damping spring, so that the clamping effect is achieved in cooperation with the rubber gasket, the excessive shaking in the transportation process is avoided, the sleeve is rotated, the fixed rod and the penetrating plate are rotationally clamped, the position of the penetrating plate can be adjusted, and the applicability is improved according to reagent tubes with different lengths. BRIEF DESCRIPTION OF DRAWINGS

[0016] Fig. 1 It is a whole structure schematic view of the utility model;

[0017] Fig. 2 It is a limiting hole structure schematic view of the utility model;

[0018] Fig. 3 It is a bearing block structure schematic view of the utility model;

[0019] Fig. 4 It is a fixed rod structure schematic view of the utility model.

[0020] In the drawing: 1, box body; 2, cover plate; 3, partition plate; 4, reagent cavity; 5, storage mechanism; 501, accommodation cavity; 502, stress air bag; 503, conveying air bag; 504, cylindrical air bag; 505, abutting block; 506, limiting hole; 507, bearing block; 508, rubber gasket; 6, sliding groove; 7, isolation plate; 8, abutting mechanism; 801, penetrating plate; 802, fixed rod; 803, sleeve; 804, damping spring; 805, rubber plate. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.

[0022] Embodiment one

[0023] As Figs. 1 to 4As shown, an NK cell immune detection kit includes a box body 1, one side of the outer wall of the box body 1 is movably connected with a cover plate 2, a partition plate 3 is fixedly installed inside the box body 1, a reagent cavity 4 is arranged on one side of the partition plate 3, and a storage mechanism 5 is arranged on the other side of the partition plate 3; the storage mechanism 5 includes a placement cavity 501 arranged on the other side of the partition plate 3, a stress air bag 502 embedded inside the placement cavity 501, a conveying air bag 503 connected to one end of the stress air bag 502 penetrating into the reagent cavity 4, a cylindrical air bag 504 connected to one end of the conveying air bag 503, a contact block 505 fixedly installed on the outer wall of the cover plate 2 corresponding to the position of the placement cavity 501, a limiting hole 506 opened inside the cylindrical air bag 504, a bearing block 507 fixedly installed below the inside of the reagent cavity 4, a rubber gasket 508 connected inside the bearing block 507, the stress air bag 502 communicates with the conveying air bag 503, and the conveying air bag 503 communicates with the cylindrical air bag 504; first, the reagent tube is inserted into the cylindrical air bag 504 through the limiting hole 506 and is preliminarily limited by penetrating into the bearing block 507, and the rubber gasket 508 is used to avoid the bumping during conveying, after the box body 1 and the cover plate 2 are closed, the contact block 505 is inserted into the placement cavity 501 and presses the stress air bag 502, the gas is conveyed through the conveying air bag 503 and filled into the cylindrical air bag 504, so that the reagent tube is supported and limited, the protection effect is achieved, and the manual multiple adjustment clamping is avoided, the reagent tube can be quickly placed, then the box body 1 is directly closed, the clamping time is saved, the reagent tube and air are avoided from being exposed for too long to be affected by temperature and oxidation.

[0024] Example two

[0025] In addition to comprising all the technical features in embodiment one, the embodiment comprises: the inside of the reagent cavity 4 is provided with a sliding groove 6 on both sides, the inside of the sliding groove 6 is slidably connected with a partition plate 7, one side of the cover plate 2 is provided with a resisting mechanism 8, the resisting mechanism 8 comprises a penetrating plate 801 penetrating out of the outer wall of the cover plate 2, the inside of the penetrating plate 801 is rotatably connected with a fixed rod 802, the end of the fixed rod 802 away from the penetrating plate 801 is sleeved with a sleeve 803, the outer wall of the penetrating plate 801 is embedded with a damping spring 804 on the other side, one end of the damping spring 804 is fixed with a rubber plate 805, the sleeve 803 is threadedly connected with the cover plate 2, and the cover plate 2 and the penetrating plate 801 form a sliding structure; the partition plate 7 penetrating through the sliding groove 6 is sleeved with a through hole on the outside of the reagent tube, and the tube opening is higher than the partition plate 7, which can play a preliminary limiting effect before the reagent tube is inserted into the cylindrical cavity 50, and after the box body 1 and the cover plate 2 are closed, the rubber plate 805 is pressed against the tube opening of the reagent tube under the driving of the penetrating plate 801 through the damping spring 804, so as to play a clamping effect in cooperation with the rubber gasket 508, and avoid excessive shaking during transportation. By rotating the sleeve 803, the penetrating plate 801 can be adjusted in position through the rotation of the fixed rod 802 and the penetrating plate 801, so as to press the reagent tube of different lengths to improve the applicability.

[0026] Working principle: first, insert the reagent tube into the limiting hole 506 of the cylindrical air bag 504 inside the reagent cavity 4, then the reagent tube penetrates the bearing block 507 to resist the rubber gasket 508, then place the partition plate 7 through the sliding groove 6 to sleeve the reagent tube, and the position is lower than the tube opening of the reagent tube, the cylindrical air bag 504 and the bearing block 507 are fixed to avoid misalignment, then the box body 1 and the cover plate 2 are closed, the resisting block 505 is inserted into the accommodating cavity 501 on one side of the partition plate 3, so as to drive the gas in the stressed air bag 502 to enter the conveying air bag 503 and the cylindrical air bag 504, so as to quickly limit and support the reagent tube. At this time, the rubber plate 805 is elastically pushed by the penetrating plate 801 and the damping spring 804, and is pressed on the tube opening of the reagent tube to be pressed tightly, and the fixed rod 802 and the penetrating plate 801 are rotationally engaged. When loosening occurs, rotate the sleeve 803 and the cover plate 2 into the threaded connection to push the penetrating plate 801 to press the reagent tube to improve the pressing force of the reagent tube.

[0027] It is obvious for those skilled in the art that the present application is not limited to the details of the above exemplary embodiments, and can be implemented in other specific forms without departing from the spirit or essential characteristics of the present application. Therefore, from any point of view, the embodiments should be regarded as exemplary and non-limiting, and the scope of the present application is defined by the appended claims rather than the above description, and therefore all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be included in the present application. Any reference signs in the claims should not be regarded as limiting the claims involved.

[0028] Furthermore, it should be understood that although the specification is described in terms of embodiments, not every embodiment includes only one independent technical solution, and the specification is described in this way only for the sake of clarity, and those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that those skilled in the art can understand.

Claims

1. An NK cell immunoassay kit, comprising a housing (1), characterized in that: A cover plate (2) is movably connected to one side of the outer wall of the box (1), and a partition plate (3) is fixedly installed inside the box (1). A reagent chamber (4) is provided on one side of the partition plate (3), and a storage mechanism (5) is provided on the other side of the partition plate (3). The storage mechanism (5) includes a placement cavity (501), which is located on the other side of the partition (3). A force-bearing airbag (502) is embedded inside the placement cavity (501). One end of the force-bearing airbag (502) that penetrates into the reagent cavity (4) is connected to a delivery airbag (503), and one end of the delivery airbag (503) is connected to a cylindrical airbag (504). An abutment block (505) is fixedly installed on the outer wall of the cover plate (2) at the position corresponding to the placement cavity (501). A limit hole (506) is opened inside the cylindrical airbag (504).

2. The NK cell immunoassay kit according to claim 1, characterized in that: A support block (507) is fixedly installed at the bottom of the reagent chamber (4), and a rubber gasket (508) is connected inside the support block (507).

3. The NK cell immunoassay kit according to claim 1, characterized in that: The force-bearing airbag (502) is connected to the delivery airbag (503), and the delivery airbag (503) is connected to the cylindrical airbag (504).

4. The NK cell immunoassay kit according to claim 1, characterized in that: The reagent chamber (4) has grooves (6) on both sides inside, and a partition plate (7) is slidably connected inside the grooves (6).

5. The NK cell immunoassay kit according to claim 1, characterized in that: A contact mechanism (8) is provided on one side of the cover plate (2). The contact mechanism (8) includes a through plate (801). The through plate (801) extends through one side of the outer wall of the cover plate (2), and a fixing rod (802) is rotatably connected inside the through plate (801). A sleeve (803) is sleeved on one end of the fixing rod (802) away from the through plate (801).

6. The NK cell immunoassay kit according to claim 5, characterized in that: A damping spring (804) is embedded on the other side of the outer wall of the through plate (801), and a rubber plate (805) is fixed to one end of the damping spring (804).

7. The NK cell immunoassay kit according to claim 5, characterized in that: The sleeve (803) is threadedly connected to the cover plate (2), and the cover plate (2) and the through plate (801) form a sliding structure.

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