Fixing device for mouse blood pressure measurement

By designing a mouse blood pressure measurement and fixation device, the problem of inconvenient mouse fixation was solved, enabling non-invasive, convenient, and accurate blood pressure measurement, thus improving the welfare of laboratory animals and the quality of research.

CN223601567UActive Publication Date: 2025-11-28FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA
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Patent Information

Application Number
CN202422777653.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Priority Date
2024-10-17
Filing Date
2024-11-14
Publication Date
2025-11-28
Estimated Expiration
2034-11-14

AI Technical Summary

Technical Problem

In traditional non-invasive blood pressure measurement techniques, mouse fixation is inconvenient, affecting the accuracy of the measurement and animal welfare.

Method used

A mouse blood pressure measurement and fixation device was designed, including a fixing cylinder, a cylinder cover, a mouse tail outlet, and a pressing component. The mouse tail is fixed by the cooperation of these components. The design of the vent and heating tube ensures the convenience and accuracy of the measurement.

Benefits of technology

This method achieves convenience and accuracy in non-invasive blood pressure measurement in mice, reduces animal suffering and infection risks, and improves the reliability and practicality of experiments.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a mouse blood pressure measurement fixing device, which belongs to the technical field of medical experiment equipment and comprises a base, a measuring component is arranged at one end of the top of the base, a fixing cylinder is arranged at the other end of the top of the base, a plurality of groups of air holes are formed in one end of the fixing cylinder, and a cylinder cover is arranged at the other end of the fixing cylinder. A mouse tail outlet hole is formed in one side of the barrel cover, pressing assemblies are arranged on the two sides of the mouse tail outlet hole, two sets of heating pipes are fixedly installed on the two sides of the fixing barrel, and an installation mechanism is arranged on the surface of the fixing barrel; the fixing cylinder, the cylinder cover, the mouse tail outlet hole and the pressing assembly are used in cooperation, the mouse tail can be conveniently fixed, researchers can conveniently conduct non-invasive blood pressure measurement on a mouse, operation is easy, convenient and rapid, powerful technical support can be provided for research of cardiovascular diseases, and the practicability of the device is improved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to medical experiment equipment technical field, concretely is a mouse blood pressure measurement fixing device. BACKGROUND

[0002] In the research and drug development process of cardiovascular diseases, accurate measurement of the blood pressure of experimental animals is crucial. Although the traditional invasive blood pressure measurement method has high accuracy, it requires surgery on the animals, which not only causes pain to the animals but also may cause infection and inflammation, affecting the experimental results. Therefore, developing a non-invasive, accurate and continuous blood pressure monitoring method is of great significance for improving research quality and animal welfare.

[0003] At present, the tail cuff method of non-invasive blood pressure measurement technology has the problem of inconvenient fixation of mice, so we need to propose a mouse blood pressure measurement fixing device. UTILITY MODEL CONTENT

[0004] The utility model aims at providing a mouse blood pressure measurement fixing device, which has the structure of fixing the mouse conveniently, to solve the problems in the background art.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical scheme: a mouse blood pressure measurement fixing device, comprising a base, one end of the top of the base is provided with a measurement assembly for measuring the blood pressure of mice, the other end of the top of the base is provided with a fixing cylinder, a plurality of groups of air holes are uniformly arranged on one end of the fixing cylinder, the other end of the fixing cylinder is provided with a cylinder cover in matching manner, the inner wall of one end of the cylinder cover is threadedly connected with one end of the surface of the fixing cylinder, a mouse tail outlet hole is formed in one side of the cylinder cover, a pressing assembly for pressing the mouse tail is arranged on the two sides of the mouse tail outlet hole and located on one side of the cylinder cover, two groups of heating pipes are fixedly installed on the two sides of the fixing cylinder, and an installation mechanism is arranged below the two groups of heating pipes and located on the surface of the fixing cylinder, and the fixing cylinder is fixedly installed on the top of the base through the installation mechanism.

[0006] Preferably, the pressing assembly comprises two groups of arc-shaped blocks arranged on the two sides of the mouse tail outlet hole and located on one side of the cylinder cover, and rubber pads are fixedly installed on the inner sides of the two groups of arc-shaped blocks.

[0007] Preferably, one side of one group of the arc-shaped blocks is fixedly installed on one side of the cylinder cover, and an elastic mechanism is arranged between the other group of the arc-shaped blocks and one side of the cylinder cover, and the arc-shaped blocks are slidingly connected to one side of the cylinder cover through the elastic mechanism.

[0008] Preferably, the elastic mechanism comprises a fixed block fixedly installed at the upper end of one side of the barrel cover, a fixed rod slidably connected in the fixed block, one end of the fixed rod penetrating through the fixed block and extending below the fixed block and being fixedly connected with the arc-shaped block, and the other end of the fixed rod penetrating through the fixed block and extending above the fixed block and being fixedly installed with a pull ring.

[0009] Preferably, a fixed plate is fixedly connected to the surface of the fixed rod and located in the fixed block, and an extension spring is arranged between the inner wall of one end of the fixed block and the surface of the fixed rod.

[0010] Preferably, the measuring assembly comprises a pressure sensor arranged at one end of the top of the base, and the pressure sensor is provided with a tail sleeve electrically connected with the pressure sensor.

[0011] Preferably, the mounting mechanism comprises a mounting block fixedly installed on the surface of the fixed barrel and a mounting groove opened at one end of the top of the base, the mounting block and the mounting groove are arranged in a matching mode, and the mounting block is slidably connected to the inner wall of the mounting groove.

[0012] Preferably, the mounting mechanism further comprises a first magnet block embedded in the bottom of the mounting block and a second magnet block embedded in the inner wall of the mounting groove, the first magnet block and the second magnet block are arranged in a corresponding mode, and the first magnet block and the second magnet block are magnetically attracted to each other.

[0013] Compared with the prior art, the utility model has the advantages that:

[0014] The fixed barrel, the barrel cover, the mouse tail hole and the pressing assembly are used in cooperation, so that the mouse tail can be fixed, the researchers can conveniently perform non-invasive blood pressure measurement on the mouse, the operation is simple, convenient and fast, and thus strong technical support can be provided for the research of cardiovascular diseases, and the practicality of the device is improved.

[0015] Other features and advantages of the present application will be described in the following description, and some will become apparent from the description, or will be understood from the practice of the present application. The purpose and other advantages of the present application can be achieved and obtained by the structure indicated in the specification and the drawings. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 It is a structural schematic view of the utility model;

[0017] Figure 2 It is a structural schematic view of the barrel cover of the utility model;

[0018] Figure 3It is a structure schematic view of the mounting mechanism of the utility model.

[0019] Figure 4 It is a structure schematic view of the elastic mechanism of the utility model.

[0020] In the drawing: 1, base; 2, fixed cylinder; 3, air hole; 4, cylinder cover; 5, mouse tail outlet hole; 6, heating pipe; 7, mounting mechanism; 701, mounting block; 702, mounting groove; 703, first magnet block; 704, second magnet block; 8, arc block; 9, elastic mechanism; 901, fixed block; 902, fixed rod; 903, pull ring; 904, fixed plate; 905, telescopic spring; 10, rubber pad; 11, pressure sensor; 12, tail sleeve. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.

[0022] Please refer to Figures 1-4 The utility model provides a mouse blood pressure measurement fixing device, including base 1, measurement subassembly, fixed cylinder 2, air hole 3, cylinder cover 4, mouse tail outlet hole 5, pressing subassembly, heating pipe 6 and mounting mechanism 7.

[0023] The top of base 1 is provided with measurement subassembly for measuring mouse blood pressure, and the other end of the top of base 1 is provided with fixed cylinder 2, and the one end of fixed cylinder 2 is uniformly provided with several groups of air hole 3, and the other end of fixed cylinder 2 is provided with cylinder cover 4, and the inner wall of one end of cylinder cover 4 is threadedly connected with the one end of the surface of fixed cylinder 2, and the mouse tail outlet hole 5 is formed in one side of cylinder cover 4, and the pressing subassembly for pressing mouse tail is arranged on both sides of mouse tail outlet hole 5 and one side of cylinder cover 4, and two groups of heating pipes 6 are fixedly installed on both sides of fixed cylinder 2, and the mounting mechanism 7 is arranged below two groups of heating pipes 6 and on the surface of fixed cylinder 2, and fixed cylinder 2 is fixedly installed on the top of base 1 through mounting mechanism 7.

[0024] Specifically, through the cooperation of the fixing cylinder 2, the cylinder cover 4, the mouse tail outlet hole 5 and the pressing assembly, when it is necessary to measure the blood pressure of the mouse, the cylinder cover 4 is first detached from one end of the fixing cylinder 2, then the mouse is inserted into the inside of the fixing cylinder 2, then the mouse tail is taken out from the mouse tail outlet hole 5, then the cylinder cover 4 is installed at one end of the fixing cylinder 2, and then the mouse tail is pressed by the pressing assembly, so that the mouse tail can be conveniently fixed, the researchers can conveniently measure the non-invasive blood pressure of the mouse, the operation is simple and convenient, and thus strong technical support can be provided for the research of cardiovascular diseases, and the practicality of the device is increased.

[0025] The pressing assembly comprises: two groups of arc-shaped blocks 8, rubber pads 10 and elastic mechanisms 9, the two groups of arc-shaped blocks 8 are arranged on the two sides of the mouse tail outlet hole 5 and located at one side of the cylinder cover 4, the inner sides of the two groups of arc-shaped blocks 8 are fixedly installed with the rubber pads 10, one side of one group of arc-shaped blocks 8 is fixedly installed at one side of the cylinder cover 4, and the other group of arc-shaped blocks 8 is provided with the elastic mechanism 9 between one side of the cylinder cover 4, and the arc-shaped block 8 is slidably connected to one side of the cylinder cover 4 through the elastic mechanism 9.

[0026] Through the cooperation of the arc-shaped block 8, the rubber pad 10 and the elastic mechanism 9, the mouse tail can be conveniently fixed, the influence of the movement of the mouse tail on the measurement is avoided, and the accuracy and reliability of the measurement result are ensured.

[0027] The elastic mechanism 9 comprises: a fixed block 901, a fixed rod 902, a pull ring 903, a fixed plate 904 and a telescopic spring 905, the fixed block 901 is fixedly installed at the upper end of one side of the cylinder cover 4, the fixed rod 902 is slidably connected in the fixed block 901, one end of the fixed rod 902 penetrates through the fixed block 901 and extends below the fixed block 901 and is fixedly connected with the arc-shaped block 8, the other end of the fixed rod 902 penetrates through the fixed block 901 and extends above the fixed block 901 and is fixedly installed with the pull ring 903, the fixed plate 904 is fixedly connected to the surface of the fixed rod 902 and located in the inside of the fixed block 901, and the telescopic spring 905 is arranged between one side of the fixed plate 904 and the inner wall of one end of the fixed block 901 and located on the surface of the fixed rod 902.

[0028] Specifically, through the cooperation of the fixed block 901, the fixed rod 902, the pull ring 903, the fixed plate 904 and the telescopic spring 905, the distance between the two groups of arc-shaped blocks 8 can be conveniently controlled, and the mouse tail can be conveniently fixed or taken out.

[0029] The measuring assembly comprises: a pressure sensor 11 and a tail sleeve 12, the pressure sensor 11 is arranged at one end of the top of the base 1, the tail sleeve 12 is arranged at one end of the pressure sensor 11, and the tail sleeve 12 and the pressure sensor 11 are electrically connected together, and through the cooperation of the pressure sensor 11 and the tail sleeve 12, the blood pressure of the mouse tail can be conveniently measured.

[0030] The mounting mechanism 7 comprises a mounting block 701, a mounting groove 702, a first magnet block 703 and a second magnet block 704, the mounting block 701 is fixedly mounted on the surface of the fixed cylinder 2, the mounting groove 702 is arranged at one end of the top of the base 1, the mounting block 701 is matched with the mounting groove 702, and the mounting block 701 is slidably connected to the inner wall of the mounting groove 702, the first magnet block 703 is embedded in the bottom of the mounting block 701, the second magnet block 704 is embedded in the inner wall of the mounting groove 702, the first magnet block 703 is correspondingly arranged with the second magnet block 704, and the first magnet block 703 and the second magnet block 704 are magnetically attracted to each other.

[0031] Specifically, through the cooperation of the mounting block 701, the mounting groove 702, the first magnet block 703 and the second magnet block 704, the fixed cylinder 2 can be conveniently mounted or dismounted, and the inside of the fixed cylinder 2 can be conveniently cleaned.

[0032] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and spirits of the utility model, and the scope of the utility model is defined by the appended claims and their equivalents.

Claims

1. A mouse blood pressure measurement fixture, characterized by: The utility model provides a mouse tail pressurization device, including base (1), one end of top of base (1) is provided with the measuring assembly for measuring mouse blood pressure, the other end of top of base (1) is provided with fixed cylinder (2), one end of fixed cylinder (2) is evenly provided with a plurality of groups of breathable hole (3), the other end of fixed cylinder (2) is provided with cylinder cover (4) in the compatible arrangement, the inner wall of one end of cylinder cover (4) is screwed with one end of fixed cylinder (2) surface, the one side of cylinder cover (4) is opened through mouse tail outlet hole (5), the both sides of mouse tail outlet hole (5) and located one side of cylinder cover (4) are provided with the pressing assembly for pressing mouse tail, both sides of fixed cylinder (2) are fixedly installed with two groups of heating pipe (6), and the surface of fixed cylinder (2) below two groups of heating pipe (6) is provided with mounting mechanism (7), and fixed cylinder (2) is fixedly installed on the top of base (1) through mounting mechanism (7).

2. The mouse blood pressure measurement fixation device according to claim 1, wherein: The pressing assembly includes two sets of arc-shaped blocks (8) disposed on both sides of the mouse tail outlet hole (5) and located on one side of the cylinder cover (4), and rubber pads (10) are fixedly installed on the inner sides of the two sets of arc-shaped blocks (8).

3. The mouse blood pressure measurement fixation device of claim 2, wherein: One side of one set of the arc-shaped blocks (8) is fixedly installed on one side of the cylinder cover (4), and an elastic mechanism (9) is provided between the other set of the arc-shaped blocks (8) and one side of the cylinder cover (4), and the arc-shaped blocks (8) are slidingly connected to one side of the cylinder cover (4) through the elastic mechanism (9).

4. The mouse blood pressure measurement fixation device of claim 3, wherein: The elastic mechanism (9) includes a fixed block (901) fixedly installed on the upper end of one side of the cylinder cover (4), a fixed rod (902) slidingly connected in the fixed block (901), one end of the fixed rod (902) penetrating through the fixed block (901) and extending below the fixed block (901) and fixedly connected with the arc-shaped block (8), and a pull ring (903) fixedly installed on the other end of the fixed rod (902) and extending above the fixed block (901).

5. The mouse blood pressure measurement fixation device of claim 4, wherein: A fixed plate (904) is fixedly connected to the surface of the fixed rod (902) and located in the fixed block (901), and a telescopic spring (905) is arranged between one side of the fixed plate (904) and the inner wall of one end of the fixed block (901) and located on the surface of the fixed rod (902).

6. The mouse blood pressure measurement fixation device of claim 1, wherein: The measuring assembly includes a pressure sensor (11) disposed on one end of the top of the base (1), and a tail sleeve (12) is arranged on one end of the pressure sensor (11) and electrically connected with the pressure sensor (11).

7. The mouse blood pressure measurement fixation device of claim 1, wherein: The mounting mechanism (7) includes a mounting block (701) fixedly installed on the surface of the fixed cylinder (2) and a mounting groove (702) opened on one end of the top of the base (1), the mounting block (701) is arranged in the compatible arrangement with the mounting groove (702), and the mounting block (701) is slidingly connected to the inner wall of the mounting groove (702).

8. The mouse blood pressure measurement fixation device of claim 7, wherein: The mounting mechanism (7) further comprises a first magnet block (703) embedded in the bottom of the mounting block (701) and a second magnet block (704) embedded in the inner wall of the mounting groove (702), the first magnet block (703) and the second magnet block (704) are correspondingly arranged, and the first magnet block (703) and the second magnet block (704) are magnetically attracted to each other.