Reagent needle and sample analyzer

Abstract

The utility model is applicable to the technical field of medical instruments, and provides a reagent needle and a sample analyzer, the reagent needle comprises a liquid taking needle, the liquid taking needle is provided with a reagent accommodating cavity and is used for sucking reagent liquid and temporarily storing the reagent liquid in the reagent accommodating cavity; the sleeve layer is sleeved on the periphery of the liquid taking needle; the heating layer is arranged between the liquid taking needle and the sleeve layer and used for being electrically connected with an external heating circuit and providing heat for the reagent liquid temporarily stored in the reagent containing cavity; the shielding layer is arranged between the liquid taking needle and the heating layer; the liquid taking needle is used for being electrically connected with an external liquid level detection circuit, so that the liquid level detection circuit detects liquid level information of the reagent liquid in the reagent accommodating cavity through the liquid taking needle; the shielding layer is used for being electrically connected with a grounding wire of the liquid level detection circuit so that the liquid taking needle and the shielding layer can be connected in a common-ground mode. The influence of PWM pulse waves on liquid level detection during heating of the heating layer is shielded through the shielding layer, heating and liquid level detection can be carried out at the same time, and the accuracy of liquid level detection can be guaranteed.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the medical instrument technical field especially relates to a reagent needle and sample analyzer. BACKGROUND

[0002] Sample analyzer is a kind of equipment commonly used in medical laboratory, and it detects certain specific chemical components in sample by mixing sample and reagent reaction.In sample analysis, sample usually refers to the blood, urine or other body fluids of the person to be detected, and reagent is the chemical for realizing chemical reaction and analysis test.

[0003] Sample analyzer usually includes automatic reagent adding function, that is, reagent is sucked from reagent storage device, and then reagent is added to reaction vessel to react with sample in reaction vessel.Because reagent is usually stored in low-temperature environment, reagent needle needs to heat the reagent liquid sucked to reduce or even eliminate the influence of low-temperature reagent on sample.Reagent needle usually includes steel needle layer, heating layer and steel sleeve layer distributed from inside to outside, and steel needle layer is hollow tube that can suck reagent.

[0004] When sucking reagent, liquid level detection needs to be carried out, but because heating layer is connected to external control panel, the capacitance signal between steel needle layer and steel sleeve layer is affected, and when reagent needle carries out liquid level detection under heating condition, because heating signal is pulse wave controlled by PWM, the influence on the capacitance signal between steel needle layer and steel sleeve layer is further increased, leading to abnormal liquid level detection.In addition, temperature sensor also exists between steel needle layer and steel sleeve layer, and when temperature is measured, a voltage needs to be applied to temperature sensor, which also affects the capacitance signal between steel needle layer and steel sleeve layer when detecting liquid level, and further leads to abnormal liquid level detection. SUMMARY

[0005] The utility model embodiment provides a kind of reagent needle, to solve the problem of inaccurate liquid level detection of existing reagent needle.

[0006] The utility model embodiment is realized as follows, a kind of reagent needle, comprising:

[0007] Liquid taking needle, liquid taking needle has reagent containing cavity, for sucking reagent liquid and temporarily storing in reagent containing cavity;

[0008] Sleeve layer is sleeved on the outer periphery of liquid taking needle;

[0009] Heating layer is arranged between liquid taking needle and sleeve layer, and heating layer is used to be electrically connected with external heating circuit, and provides heat for the reagent liquid temporarily stored in reagent containing cavity;And

[0010] Shielding layer is arranged between liquid taking needle and heating layer;

[0011] The liquid taking needle is electrically connected with an external liquid level detection circuit to enable the liquid level detection circuit to detect the liquid level information of the reagent liquid in the reagent accommodating cavity through the liquid taking needle.

[0012] The shielding layer is electrically connected with a grounding wire of the liquid level detection circuit to enable the liquid taking needle and the shielding layer to be connected to the ground.

[0013] Further, the reagent needle further comprises a temperature sensor, which is arranged in close contact with the heating layer and between the sleeve layer and the shielding layer.

[0014] Further, the shielding layer has a circular or C-shaped cross section.

[0015] Further, the shielding layer comprises at least one of copper, aluminum and silver.

[0016] Further, the liquid taking needle, the shielding layer, the heating layer and the sleeve layer are electrically isolated by filling an insulating and heat-insulating material.

[0017] Further, the insulating and heat-insulating material comprises at least one of Teflon, perfluoroalkoxy resin, fluorinated ethylene propylene copolymer, polyvinylidene fluoride, expanded polytetrafluoroethylene and phenolic resin.

[0018] Further, the reagent needle further comprises a wiring connector assembly, which is provided with a vent hole in communication with the reagent accommodating cavity of the liquid taking needle, and the vent hole is used to be connected with an external air pressure device.

[0019] Further, the wiring connector assembly is electrically connected with the liquid taking needle, and the wiring connector assembly is used to be electrically connected with the liquid level detection circuit.

[0020] Further, the reagent needle further comprises a first wire, a second wire and a third wire.

[0021] The first end of the first wire is electrically connected with the heating layer, and the second end of the first wire is used to be electrically connected with a heating circuit.

[0022] The first end of the second wire is electrically connected with the shielding layer, and the second end of the second wire is used to be electrically connected with a grounding wire of the liquid level detection circuit.

[0023] The first end of the third wire is electrically connected with the temperature sensor, and the second end of the third wire is used to be electrically connected with a temperature detection circuit.

[0024] In a second aspect, the application further provides a sample analyzer, comprising:

[0025] a controller;

[0026] a driving device electrically connected with the controller;

[0027] a fixing member connected with the driving device;

[0028] a circuit module electrically connected with the controller, the circuit module comprising a heating circuit, a liquid level detection circuit and a temperature detection circuit, and

[0029] the reagent needle as above;

[0030] the fixing member is connected with the reagent needle and used to drive the reagent needle to move within a preset range under the driving of the driving device;

[0031] the reagent needle is electrically connected with the heating circuit, the liquid level detection circuit and the temperature detection circuit respectively, and when the controller controls the pulse signal of the heating circuit to heat and / or detects the voltage signal of the temperature detection circuit, the detection signal of the liquid level detection circuit is detected synchronously to determine the liquid level information of the reagent liquid in the reagent accommodating cavity.

[0032] The reagent needle provided by the application comprises a liquid taking needle, a sleeve layer arranged outside the liquid taking needle, a heating layer arranged between the liquid taking needle and the sleeve layer, and a shielding layer arranged between the liquid taking needle and the heating layer. The liquid taking needle is used to be electrically connected with an external liquid level detection circuit, so that the liquid level detection circuit detects the liquid level information of the reagent liquid in the reagent accommodating cavity through the liquid taking needle. The shielding layer is used to be electrically connected with the grounding wire of the liquid level detection circuit, so that the liquid taking needle and the shielding layer are connected in common. By arranging the shielding layer between the liquid taking needle and the heating layer and electrically connecting the shielding layer with the grounding wire of the liquid level detection circuit, the shielding layer serves as a reference surface for liquid level detection. For example, the liquid level detection adopts a detection capacitor mode, so that the capacitance value of the reagent liquid level detection is the capacitance between the liquid taking needle and the shielding layer. Thus, the influence of the PWM pulse wave of the heating layer on the liquid level detection is shielded, the heating and the liquid level detection can be performed simultaneously, and the accuracy of the liquid level detection can be ensured. BRIEF DESCRIPTION OF DRAWINGS

[0033] Figure 1 is a structural schematic diagram of one embodiment of the reagent needle provided by the application;

[0034] Figure 2 is a structural schematic diagram of one embodiment of the reagent needle provided by the application without a fixing member;

[0035] Figure 3 is Figure 2 is an enlarged schematic diagram of A1 in FIG. 1;

[0036] Figure 4 is a front view schematic diagram of one embodiment of the reagent needle provided by the application;

[0037] Figure 5 is a sectional view along Figure 4A-A line of the cross-sectional view schematic diagram;

[0038] Figure 6 is Figure 5 A2 part of the enlarged schematic diagram;

[0039] Figure 7 is an embodiment of the reagent needle heating circuit provided by the present application Circuit structure schematic diagram of circuit structure;

[0040] Figure 8 is an embodiment of the reagent needle temperature detection circuit provided by the present application Circuit structure schematic diagram of circuit structure;

[0041] Figure 9 is another embodiment of the reagent needle temperature detection circuit provided by the present application Circuit structure schematic diagram of circuit structure.

[0042] Figure legend: 100-liquid taking needle, 200-sleeve layer, 300-heating layer, 400-shielding layer, 500-temperature sensor, 600-wiring connector assembly, 610-vent hole, 700-fixing piece. DETAILED DESCRIPTION

[0043] In order to make the purpose, technical scheme and advantages of the utility model clearer and more apparent, the utility model will be further described in detail below in combination with the drawings and examples. The examples of the examples are shown in the drawings, wherein the same or similar reference numerals represent the same or similar elements or elements with the same or similar functions throughout. The examples described below by referring to the drawings are exemplary and are only used to explain the utility model, and cannot be understood as limiting the utility model. In addition, it should be understood that the specific examples described herein are only used to explain the utility model and cannot be used to limit the utility model.

[0044] In the description of the utility model, it should be understood that the terms "length", "width", "upper", "lower", "left", "right", "horizontal", "top", "bottom" and the like indicate the orientation or positional relationship shown in the drawings, which is only for the convenience of describing the utility model and simplifying the description, and does not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, therefore it cannot be understood as limiting the utility model.

[0045] In addition, the terms "first", "second" are only for the purpose of description, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features limited by "first", "second" can explicitly or implicitly include one or more features. In the description of the utility model, the meaning of "multiple" is two or more than two, unless otherwise specifically limited.

[0046] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection, an electrical connection, or a connection that allows for communication; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0047] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0048] The following disclosure provides numerous different embodiments or examples for implementing various structures of the present invention. To simplify the disclosure, specific examples of components and arrangements are described below. These are merely examples and are not intended to limit the scope of the invention. Furthermore, reference values ​​and / or reference letters may be repeated in different examples; such repetition is for simplification and clarity and does not in itself indicate a relationship between the various embodiments and / or arrangements discussed. In addition, examples of various specific processes and materials are provided in this invention, but those skilled in the art will recognize the application of other processes and / or the use of other materials.

[0049] The reagent needle provided by the application comprises a liquid taking needle, the liquid taking needle has a reagent accommodating cavity, is used for sucking and temporarily storing reagent liquid in the reagent accommodating cavity, a sleeve layer is sleeved on the outer periphery of the liquid taking needle, a heating layer is arranged between the liquid taking needle and the sleeve layer, the heating layer is used for being electrically connected with an external heating circuit and providing heat for the reagent liquid temporarily stored in the reagent accommodating cavity, and a shielding layer is arranged between the liquid taking needle and the heating layer; the liquid taking needle is used for being electrically connected with an external liquid level detection circuit, so that the liquid level detection circuit detects the liquid level information of the reagent liquid in the reagent accommodating cavity through the liquid taking needle; and the shielding layer is used for being electrically connected with the grounding wire of the liquid level detection circuit, so that the liquid taking needle and the shielding layer are commonly grounded. By arranging the shielding layer between the liquid taking needle and the heating layer and electrically connecting the shielding layer with the grounding wire of the liquid level detection circuit, the shielding layer serves as a reference surface for liquid level detection, for example, the liquid level detection adopts a detection capacitance mode, so that the capacitance value of the reagent liquid level detection is the capacitance between the liquid taking needle and the shielding layer, thereby shielding the influence of the PWM pulse wave of the heating layer on the liquid level detection during heating, and the heating and the liquid level detection can be simultaneously performed and the accuracy of the liquid level detection can be ensured.

[0050] As shown in Figures 1 to 2 , one embodiment of the application provides a reagent needle, comprising:

[0051] a liquid taking needle 100, the liquid taking needle 100 has a reagent accommodating cavity, is used for sucking and temporarily storing reagent liquid in the reagent accommodating cavity;

[0052] a sleeve layer 200 sleeved on the outer periphery of the liquid taking needle 100;

[0053] a heating layer 300 arranged between the liquid taking needle 100 and the sleeve layer 200, the heating layer 300 is used for being electrically connected with an external heating circuit and providing heat for the reagent liquid temporarily stored in the reagent accommodating cavity; and

[0054] a shielding layer 400 arranged between the liquid taking needle 100 and the heating layer 300;

[0055] the liquid taking needle 100 is used for being electrically connected with an external liquid level detection circuit (not shown in the figure), so that the liquid level detection circuit detects the liquid level information of the reagent liquid in the reagent accommodating cavity through the liquid taking needle 100;

[0056] the shielding layer 400 is used for being electrically connected with the grounding wire of the liquid level detection circuit, so that the liquid taking needle 100 and the shielding layer 400 are commonly grounded.

[0057] In implementation, the liquid taking needle 100 is in a hollow tubular structure, and the hollow tube of the liquid taking needle 100 is a reagent accommodating cavity, so that the liquid taking needle 100 can suck the reagent liquid and temporarily store the sucked reagent liquid in the reagent accommodating cavity. In subsequent process, the liquid taking needle 100 can carry the temporarily stored reagent liquid to a designated position, for example, after sucking the reagent liquid, the liquid taking needle 100 moves above the test tube, and then sprays the reagent liquid into the test tube, so that the reagent liquid reacts with the sample in the test tube to realize the sample detection function.

[0058] The shielding layer 400, the heating layer 300 and the sleeve layer 200 are sequentially sleeved on the outer periphery of the liquid taking needle 100, that is, the liquid taking needle 100, the shielding layer 400, the heating layer 300 and the sleeve layer 200 are sequentially distributed from inside to outside, and the sleeve layer 200 can be regarded as a shell of the reagent needle and plays a role of supporting and protecting the internal structure.

[0059] The heating layer 300 can generate heat under the control of the heating circuit, so as to provide heat for the reagent liquid temporarily stored in the reagent accommodating cavity, so as to heat the low-temperature stored reagent liquid to a preset temperature, for example, the same temperature as the sample, so as to ensure that the sample is not affected by the low-temperature reagent liquid after the reagent liquid and the sample are mixed, and ensure the accuracy of sample detection.

[0060] Optionally, the heating layer 300 can adopt an electric heating wire, a resistance sheet or other components with heating function, which is not limited.

[0061] For example, the liquid level detection adopts a detection capacitor, the shielding layer 400 is arranged between the liquid taking needle 100 and the heating layer 300, that is, the liquid taking needle 100 and the heating layer 300 are isolated by the shielding layer 400, and the shielding layer 400 is also electrically connected with the ground wire of the heating circuit, so that when the liquid level detection circuit detects the liquid level information of the reagent liquid in the reagent accommodating cavity through the liquid taking needle 100, the shielding layer 400 is used as a reference surface for liquid level detection, and therefore the actual liquid level detection capacitor value is the capacitor between the liquid taking needle 100 and the shielding layer 400. The influence of the PWM pulse wave output by the heating circuit to the heating layer 300 to control the heating of the heating layer 300 on the liquid level detection can be shielded, so as to avoid the case that the liquid level detection fails due to the heating of the reagent needle at the same time.

[0062] It should be noted that the liquid level detection adopting the detection capacitor is an example of one embodiment of the present application, and is not a specific limitation on the present application. In other embodiments, the liquid level detection can also adopt other ways, which are not specifically limited.

[0063] Optionally, the shielding layer 400 can adopt a hollow tubular structure, that is, the cross section of the shielding layer 400 is circular.

[0064] It should be noted that the cross section of the shielding layer 400 can be a circle or an ellipse, and is not limited to a specific shape.

[0065] Alternatively, the shielding layer 400 can also have an arc-shaped sheet structure, i.e., the cross section of the shielding layer 400 is C-shaped.

[0066] As a possible implementation, the shielding layer 400 includes at least one of copper, aluminum, and silver, and can achieve the shielding function, and is not limited to a specific material.

[0067] The reagent needle provided in the application includes a liquid taking needle 100, the liquid taking needle 100 has a reagent accommodating cavity for absorbing and temporarily storing reagent liquid in the reagent accommodating cavity; a sleeve layer 200 sleeved on the outer periphery of the liquid taking needle 100; a heating layer 300 arranged between the liquid taking needle 100 and the sleeve layer 200, the heating layer 300 is used for electrically connecting with an external heating circuit and providing heat for the reagent liquid temporarily stored in the reagent accommodating cavity; and a shielding layer 400 arranged between the liquid taking needle 100 and the heating layer 300; the liquid taking needle 100 is used for electrically connecting with an external liquid level detection circuit, so that the liquid level detection circuit detects the liquid level information of the reagent liquid in the reagent accommodating cavity through the liquid taking needle 100; and the shielding layer 400 is used for electrically connecting with the ground wire of the liquid level detection circuit, so that the liquid taking needle 100 and the shielding layer 400 are connected in common. By arranging the shielding layer 400 between the liquid taking needle 100 and the heating layer 300, and electrically connecting the shielding layer 400 with the electrical connection wire of the liquid level detection circuit, when the liquid taking needle 100 performs liquid level detection, the shielding layer 400 serves as a reference surface for liquid level detection, for example, the liquid level detection adopts a detection capacitor mode, so that the capacitance value of the reagent liquid level detection is the capacitance between the liquid taking needle 100 and the shielding layer 400, thereby shielding the influence of the PWM pulse wave of the heating layer 300 on the liquid level detection when heating, and the heating and liquid level detection can be performed simultaneously, and the accuracy of the liquid level detection can be ensured.

[0068] In some possible embodiments, the circuit structure of the heating circuit is as shown in Figure 7 As shown in FIG. 11, the heating circuit includes a switch tube Q11, a switch tube Q12, a resistor R121, a resistor R124, a resistor R125, a resistor R128, and a temperature protection switch J19, wherein the switch tube Q11 is a p-gate MOS tube, the switch tube Q12 is an n-gate MOS tube, J20 can be seen as the heating layer 300 or a port for connecting the heating layer 300, TIM1_CH1 represents a connection controller, and the specific circuit structure can be referred to in FIG. 12. Figure 7When heating is needed, the controller outputs a signal to switch tube Q12 through TIM1_CH1, switch tube Q12 is turned on, and then switch tube Q11 is turned on, power supply VDD is supplied to J20 through switch tube Q11, and the heating layer 300 generates heat, while the liquid level detection circuit detects the liquid level information of the reagent liquid in the reagent storage cavity through the liquid taking needle 100. The process of liquid level detection does not need to stop heating, so as to better maintain the temperature in the predetermined range.

[0069] In some optional embodiments, the reagent needle provided by the application further comprises a temperature sensor 500, which is arranged in close contact with the heating layer 300 and between the sleeve layer 200 and the shielding layer 400.

[0070] The temperature sensor 500 is used to detect the temperature of the reagent needle, so as to ensure that the heating layer 300 heats the reagent liquid stored in the reagent storage cavity to a predetermined temperature range, and improve the test accuracy.

[0071] Since the temperature sensor 500 needs to be applied with a voltage by an external temperature detection circuit when working, by arranging the temperature sensor 500 between the sleeve layer 200 and the shielding layer 400, the temperature sensor 500 is located at the outer periphery of the shielding layer 400, so that the shielding layer 400 can shield the influence of the temperature sensor 500 on the liquid level detection when working. When detecting the liquid level, the temperature detection does not need to be turned off, which ensures that the temperature of the reagent liquid stored in the reagent storage cavity is in the set range while ensuring the accuracy of the liquid level detection.

[0072] Exemplarily, the temperature detection circuit comprises J3, chip U3, chip U6, chip U7, resistor R94, resistor R98, resistor R103, capacitor C36, capacitor C58, capacitor C81, capacitor C85, capacitor C86, capacitor C88, capacitor C90, capacitor C91, capacitor C92, capacitor C93, capacitor C94, capacitor C95, capacitor C99 and capacitor C100. The circuit structure of the temperature detection circuit can be referred to Figure 8 The above is not repeated.

[0073] In implementation, J3 of the temperature detection circuit is used to connect the temperature sensor 500, that is, J3 can be regarded as a temperature detection channel, J3 is connected to chip U3 and chip U7, chip U3 is connected to chip U6, and chip U3, chip U7 and chip U6 are connected to the controller, for example, the controller is connected to chip U3 through MUX1_A0, MUX1_A1 and MUX1_EN, the controller is connected to chip U7 through MUX2_A0, MUX2_A1 and MUX2_EN, and the controller is connected to chip U6 through ADC_MISO, ADC_MOSI and ADC_SCK. When temperature detection is performed, the controller outputs a control signal to chip U3, chip U7 and chip U6, chip U6 cooperates with chip U3 and chip U7 to control the temperature sensor 500 to work, and the detection signal of the temperature sensor 500 is fed back to the controller, so as to realize the temperature detection function.

[0074] It should be noted that the temperature detection circuit can also include a plurality of temperature detection channels, for example, the temperature detection circuit can also include four temperature detection channels, as shown in Figure 9 J3 represents temperature detection channel 1, J4 represents temperature detection channel 2, J5 represents temperature detection channel 3, and J6 represents temperature detection channel 4. Each temperature detection channel can connect one temperature sensor 500, and multiple points can collect temperature information to improve detection accuracy.

[0075] In some embodiments, the reagent needle provided by the application further includes a first lead wire (not shown in the figure), a second lead wire (not shown in the figure) and a third lead wire (not shown in the figure);

[0076] The first end of the first lead wire is electrically connected to the heating layer 300, and the second end of the first lead wire is used to be electrically connected to the heating circuit;

[0077] The first end of the second lead wire is electrically connected to the shielding layer 400, and the second end of the second lead wire is used to be electrically connected to the ground wire of the liquid level detection circuit;

[0078] The first end of the third lead wire is electrically connected to the temperature sensor 500, and the second end of the third lead wire is used to be electrically connected to the temperature detection circuit.

[0079] In some optional embodiments, the liquid taking needle 100, the shielding layer 400, the heating layer 300 and the sleeve layer 200 are thermally and electrically isolated by filling insulating and heat insulating materials.

[0080] Optionally, the insulating and heat insulating material includes at least one of Teflon, perfluoroalkoxy resin, fluorinated ethylene propylene copolymer, polyvinylidene fluoride, expanded polytetrafluoroethylene and phenolic resin.

[0081] In some optional embodiments, the reagent needle provided by the application further comprises a connecting pipe assembly 600, which is provided with a vent hole 610 in communication with the reagent accommodating cavity of the reagent needle 100, and the vent hole 610 is used to connect with an external air pressure device.

[0082] The air pressure device is used to provide negative pressure or positive pressure for the reagent needle 100, so that the reagent accommodating cavity in the reagent needle 100 is in negative pressure to suck the reagent liquid, or the reagent accommodating cavity in the reagent needle 100 is in positive pressure to spray the reagent liquid temporarily stored in the reagent accommodating cavity to a designated position.

[0083] Optionally, the connecting pipe assembly 600 has electrical conductivity, and the reagent needle 100 is electrically connected with the liquid level detection circuit through the connecting pipe assembly 600, so that the liquid level detection circuit can detect the liquid level information of the reagent liquid in the reagent accommodating cavity through the connecting pipe assembly 600 and the reagent needle 100. The connecting pipe assembly 600 realizes the electrical connection function between the reagent needle 100 and the liquid level detection circuit while realizing the communication function of the reagent needle 100 and the air pressure device, reduces the hardware investment, and reduces the product cost.

[0084] In use, the reagent liquid is usually stored in a low-temperature environment. The heating circuit outputs a PWM pulse signal to the heating layer 300 to control the heating layer 300 to heat, so as to provide heat for the reagent liquid temporarily stored in the reagent accommodating cavity. The temperature detection circuit detects the temperature of the reagent needle through the temperature sensor 500. Since the heating layer 300 and the temperature sensor 500 are located outside the periphery of the shielding layer 400, the shielding layer 400 can shield the influence of the heating layer 300 and the temperature sensor 500 on the liquid level detection when working, so that the liquid level detection circuit can detect the liquid level information of the reagent liquid in the reagent accommodating cavity at the same time, and ensure the accuracy of the liquid level detection.

[0085] In some optional embodiments, the application further provides a sample analyzer, comprising:

[0086] a controller (not shown in the figure);

[0087] a driving device (not shown in the figure) electrically connected with the controller;

[0088] a fixing member 700 connected with the driving device;

[0089] a circuit module electrically connected with the controller, the circuit module comprising a heating circuit, a liquid level detection circuit and a temperature detection circuit, and

[0090] a reagent needle as described above;

[0091] The fixing member 700 is connected with the reagent needle, and is used to drive the reagent needle to move in a predetermined range under the driving of the driving device;

[0092] The reagent needle is electrically connected with the heating circuit, the liquid level detection circuit and the temperature detection circuit respectively, and when the controller controls the pulse signal of the heating circuit to heat and / or detects the voltage signal of the temperature detection circuit, the detection signal of the liquid level detection circuit is detected synchronously to determine the liquid level information of the reagent liquid in the reagent accommodating cavity.

[0093] The sample analyzer includes but is not limited to a reagent area, a sample area and a reaction area, etc., which are not limited. The reagent area is used to store reagents of different types and different purposes, the sample area is used to temporarily store a plurality of samples, and the reaction area can provide an environment required for testing, such as a specific temperature, humidity or rotation speed, etc., which are not limited.

[0094] During the testing process, the sample is transported to the reaction area. For example, the sample analyzer is provided with a mechanical hand, and the mechanical hand is electrically connected with the controller, so that the controller can control the mechanical hand to clamp a sample test tube containing the sample, and then move the sample test tube to the reaction area to pour into a designated reaction vessel. Then the controller controls the driving device to move the reagent needle to the reagent area to suck the reagent liquid. In this process, the controller controls the heating layer 300 to heat through the heating circuit to provide heat for the reagent liquid temporarily stored in the reagent accommodating cavity. The controller obtains the temperature of the reagent needle in real time through the temperature detection circuit of the temperature sensor 500. At the same time, the controller detects the liquid level information of the reagent liquid in the reagent accommodating cavity through the liquid level detection circuit to ensure the accuracy of the liquid level detection. Then the controller controls the driving device to move the reagent needle to the reaction area, and then outputs the reagent liquid to the designated reaction vessel to mix and react with the sample.

[0095] Those skilled in the art can clearly understand that, for the convenience and brevity of description, the structure and implementation principle of the reagent needle in the sample analyzer described above can refer to the structure and implementation principle of the reagent needle in the foregoing embodiments, which will not be repeated here.

[0096] The reagent needle provided by the application comprises a liquid taking needle 100, the liquid taking needle 100 has a reagent accommodating cavity, and is used for sucking and temporarily storing reagent liquid in the reagent accommodating cavity; a sleeve layer 200 is arranged on the outer periphery of the liquid taking needle 100; a heating layer 300 is arranged between the liquid taking needle 100 and the sleeve layer 200, the heating layer 300 is used for being electrically connected with an external heating circuit, and provides heat for the reagent liquid temporarily stored in the reagent accommodating cavity; and a shielding layer 400 is arranged between the liquid taking needle 100 and the heating layer 300; the liquid taking needle 100 is used for being electrically connected with an external liquid level detection circuit, so that the liquid level detection circuit detects liquid level information of the reagent liquid in the reagent accommodating cavity through the liquid taking needle 100; and the shielding layer 400 is used for being electrically connected with a grounding wire of the liquid level detection circuit, so that the liquid taking needle 100 and the shielding layer 400 are connected in common. By arranging the shielding layer 400 between the liquid taking needle 100 and the heating layer 300, and electrically connecting the shielding layer 400 with the grounding wire of the liquid level detection circuit, when the liquid taking needle 100 performs liquid level detection, the shielding layer 400 serves as a reference surface of the liquid level detection, for example, the liquid level detection adopts a detection capacitance mode, so that a capacitance value of the reagent liquid level detection is a capacitance between the liquid taking needle 100 and the shielding layer 400, thereby shielding the influence of the PWM pulse wave of the heating layer 300 on the liquid level detection when the heating layer 300 is heated, and the heating and the liquid level detection can be simultaneously performed, and the accuracy of the liquid level detection can be ensured.

[0097] The above is only a preferred embodiment of the utility model, and is not used to limit the utility model, and any modification, equivalent replacement and improvement within the spirit and principle of the utility model should be included in the protection scope of the utility model.

Claims

1. A reagent needle, characterized by, The reagent needle comprises: a liquid taking needle having a reagent accommodating cavity for sucking and temporarily storing reagent liquid in the reagent accommodating cavity; a sleeve layer sleeved on the outer periphery of the liquid taking needle; a heating layer arranged between the liquid taking needle and the sleeve layer, the heating layer being used for electrically connecting with an external heating circuit and providing heat for the reagent liquid temporarily stored in the reagent accommodating cavity; and a shielding layer arranged between the liquid taking needle and the heating layer; the liquid taking needle is used for electrically connecting with an external liquid level detection circuit, so that the liquid level detection circuit detects liquid level information of the reagent liquid in the reagent accommodating cavity through the liquid taking needle; the shielding layer is used for electrically connecting with a ground wire of the liquid level detection circuit, so that the liquid taking needle and the shielding layer are connected in common.

2. The reagent needle of claim 1, wherein The reagent needle further comprises a temperature sensor, which is arranged in close contact with the heating layer and between the sleeve layer and the shielding layer.

3. The reagent needle of claim 1, wherein The shielding layer has a circular or C-shaped cross section.

4. The reagent needle of claim 1 or 3, wherein The shielding layer comprises at least one of copper, aluminum and silver.

5. The reagent needle of claim 1, wherein The liquid taking needle, the shielding layer, the heating layer and the sleeve layer are electrically isolated by filling insulating and heat insulating materials.

6. The reagent needle of claim 1, wherein The reagent needle further comprises a wiring connector assembly, which is provided with a vent hole in communication with the reagent accommodating cavity of the liquid taking needle, and the vent hole is used for connecting with an external air pressure device.

7. The reagent needle of claim 6, wherein The wiring connector assembly is electrically connected with the liquid taking needle, and is used for electrically connecting with the liquid level detection circuit.

8. The reagent needle of claim 2, wherein The reagent needle further comprises a first lead wire, a second lead wire and a third lead wire; a first end of the first lead wire is electrically connected with the heating layer, and a second end of the first lead wire is used for electrically connecting with the heating circuit; a first end of the second lead wire is electrically connected with the shielding layer, and a second end of the second lead wire is used for electrically connecting with a ground wire of the liquid level detection circuit; a first end of the third lead wire is electrically connected with the temperature sensor, and a second end of the third lead wire is used for electrically connecting with a temperature detection circuit.

9. A sample analyzer characterized by, The reagent needle comprises: a controller; a driving device electrically connected with the controller; a fixing member connected with the driving device; a circuit module electrically connected with the controller, the circuit module comprising a heating circuit, a liquid level detection circuit and a temperature detection circuit, and the reagent needle according to any one of claims 1 to 8; the fixing member is connected with the reagent needle, and is used for driving the reagent needle to move in a preset range under the driving of the driving device; the reagent needle is electrically connected with the heating circuit, the liquid level detection circuit and the temperature detection circuit respectively, and when the controller controls the pulse signal of the heating circuit to heat and / or detects the voltage signal of the temperature detection circuit, the detection signal of the liquid level detection circuit is synchronously detected to determine the liquid level information of the reagent liquid in the reagent accommodating cavity.

Images