Microscopic observation system for cell factory

Abstract

The utility model discloses a microscopic observation system for a cell factory. The microscopic observation system comprises a main body frame, a front-back translation mechanism, a lifting mechanism, a focusing movement mechanism and a microscope observation module, a front-back translation mechanism and a lifting mechanism are arranged in the main frame from bottom to top, the lifting mechanism penetrates through the top surface of the main frame, a supporting platform is arranged at the top of the lifting mechanism, and the cell factory is arranged on the supporting platform; focusing moving mechanisms are arranged on the top surface of the main body frame and located on the left side and the right side of the supporting platform respectively, and microscope observation modules are installed above the focusing moving mechanisms; the system further comprises a display control module. And the display control module is electrically connected with the lifting mechanism, the front-back translation mechanism, the focusing movement mechanism and the microscope observation module. According to the utility model, automatic up-and-down and front-and-back movement of the cell factory and left-and-right movement of the microscope observation module are realized for observation operation, culture, growth cultivation and lesion microscope observation of the cell factory are realized, the automation degree is high, the overall integration degree is high, and the occupied volume is small.

Description

TECHNICAL FIELD

[0001] The utility model relates to biological technology research equipment technical field, concretely relates to a cell factory microscopic observation system. BACKGROUND

[0002] In cell biology research and cell product production, it is crucial to accurately observe the growth state of cells in the cell factory. At present, the existing cell observation means has many deficiencies. For example, relying on manual observation by flashlight, only the observation results can be analyzed by experience, and it is difficult to obtain growth condition judgment basis pictures, which requires very high experience; some traditional microscopic observation methods are complicated to operate, and it is difficult to realize continuous and real-time monitoring. At the same time, the existing observation equipment often cannot provide comprehensive cell growth information, which cannot meet the needs of scientific research and production for efficient and accurate observation of the cell factory. UTILITY MODEL CONTENT

[0003] In order to solve the above-mentioned deficiencies in the prior art, the utility model provides a cell factory microscopic observation system, which automatically controls the up-down, front-back positions of the cell factory and the distance between the cell factory and the microscopic observation module for focusing fine adjustment, can provide high-resolution cell images, and is helpful for researchers to more accurately observe cell morphology and growth state.

[0004] In order to achieve the above technical purpose, the utility model adopts the technical scheme of:

[0005] A cell factory microscopic observation system, comprising a main frame, a front-back translation mechanism, a lifting mechanism, a focusing movement mechanism and a microscope observation module; the main frame is provided with the front-back translation mechanism and the lifting mechanism from bottom to top, the lifting mechanism penetrates the top surface of the main frame, the top of the lifting mechanism is provided with a support platform, and the cell factory is placed on the support platform; the main frame top surface is provided with the focusing movement mechanism on the left and right sides of the support platform, and the microscope observation module is installed above the focusing movement mechanism; further comprising a display control module; the display control module is electrically connected with the lifting mechanism, the front-back translation mechanism, the focusing movement mechanism and the microscope observation module, used for adjusting and controlling the front-back, up-down positions of the cell factory and the left-right position of the microscope observation module, and displaying and storing the data shot by the microscope observation module.

[0006] Further, the microscope observation module comprises a camera, a microscope and a light source, the camera is arranged at the rear end of the microscope, and the light source is arranged at the front end of the microscope.

[0007] Further, the focusing movement mechanism comprises a bottom plate and a guide rail module, the bottom plate is installed on the top surface of the main frame, the guide rail module is installed on the bottom plate, a support plate base is installed on the guide rail module, a support connecting plate is connected to the support plate base, a support plate is arranged on the support connecting plate, and the support plate is used for installing the microscope observation module.

[0008] Further, the front-back translation mechanism comprises a front-back translation module, which is installed on a fixed plate arranged in the main frame, and a lifting mechanism is installed above the front-back translation module.

[0009] Further, the lifting mechanism comprises a lifter, a lifter fixing plate is installed above the front-back translation module, the lower end of the lifter is installed on the lifter fixing plate through a lower connecting plate, and the top of the lifter is installed on the support platform through an upper connecting plate.

[0010] Further, the lifting mechanism further comprises a lifter outer cover and a lifter inner cover, the lifter inner cover is sleeved on the outer periphery of the lifter and is connected to the lower connecting plate at the bottom, the outer periphery of the lifter outer cover is fixedly connected to the main frame, a gap is arranged between the lifter outer cover and the lifter inner cover in the front-back direction, the lifter and the lifter inner cover can move in the front-back direction in the lifter outer cover, and an organ case is arranged on both sides of the lifter in the front-back direction.

[0011] Further, at least one corner of the support platform is provided with a positioning block.

[0012] Preferably, the at least one positioning block is in an "L" shape.

[0013] Further, the display control module is arranged on the top surface of the main frame and comprises a human-computer interaction control unit and a computer display unit, the human-computer interaction control unit is an HMI touch screen and is used for running and adjusting the system parameters of the human-computer interaction control system, and the computer display unit is connected to the data interface of the camera through a USB interface.

[0014] Further, an electric appliance control chamber is arranged in the main frame, the electric appliance control chamber is arranged below the display control module, and support legs and universal casters are arranged at the four corners of the bottom of the main frame.

[0015] The cell factory microscopic observation system has the following advantages:

[0016] The cell factory microscopic observation system can realize the culture, growth cultivation and pathological microscopic observation of the cell factory through the display control module to control the automatic up-down, front-back movement of the cell factory and the left-right movement of the microscopic observation module, and the system has high automation, high operation efficiency, low labor intensity, high overall integration and small occupied volume.

[0017] The cell factory microscopic observation system of the utility model provides high-resolution cell images, helps scientific researchers to more accurately observe cell morphology and growth state, is convenient for image storage backup, changes the previous traditional microscope observation mode, improves work efficiency, can realize cell factory liquid-free and liquid observation, and makes the observation effect clearer. BRIEF DESCRIPTION OF DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following will briefly introduce the drawings needed to be used in the embodiments, and it should be understood that the following drawings only show some embodiments of the present application, and therefore should not be regarded as a limitation to the scope, and for those skilled in the art, other related drawings can also be obtained without creative labor on the basis of these drawings.

[0019] Figure 1 is the front observation isometric view of the utility model embodiment;

[0020] Figure 2 is the back observation isometric view of the utility model embodiment;

[0021] Figure 3 is the explosion isometric view of the focusing movement mechanism and the microscope observation module;

[0022] Figure 4 is the isometric view of the front and back translation mechanism and the lifting mechanism;

[0023] Figure 5 is the explosion isometric view of Figure 4 ;

[0024] Figure 6 is the front and back contrast isometric view of the microscope observation module;

[0025] Figure 7 is the front and back contrast isometric view of the front and back translation mechanism;

[0026] Figure 8 is the isometric view of the cell factory upper part liquid-free area observation when the lifting mechanism is in the initial state;

[0027] Figure 9 is the isometric view of the cell factory lower part liquid area observation after the lifting mechanism is lifted.

[0028] Reference numerals: 1-Main frame, 2-Front-back translation mechanism, 3-Lifting mechanism, 4-Focusing movement mechanism, 5-Microscope observation module, 6-Cell factory, 7-Display control module; 11-Supporting foot, 12-Universal caster, 13-Electrical control room, 21-Front-back translation module, 22-Fixed plate, 31-Supporting platform, 311-Positioning block, 32-Lifter, 33-Lifter fixed plate, 34-Lower connecting part, 35-Lifter cover outer sleeve, 36-Lifter cover inner sleeve, 37-Bell bellows cover, 38-Upper connecting plate, 41-Base plate, 42-Guide rail module, 43-Support plate base, 44-Support connecting plate, 45-Support plate, 51-Camera, 52-Microscope, 53-Light source, 71-Human-machine interaction control unit, 72-Computer display unit, 73-Power switch, 74-Light source adjustment switch, 75-Emergency stop button. Detailed Implementation

[0029] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. The components of the embodiments of this application described and shown in the accompanying drawings can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of this application provided in the accompanying drawings is not intended to limit the scope of the claimed application, but merely represents selected embodiments of this application. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the scope of protection of this application.

[0030] A cell factory microscopic observation system, such as Figures 1-5 As shown, the system includes a main frame 1, a front-to-back translation mechanism 2, a lifting mechanism 3, a focusing and moving mechanism 4, and a microscope observation module 5. The main frame 1 contains the front-to-back translation mechanism 2 and the lifting mechanism 3 from bottom to top. The lifting mechanism 3 extends through the top surface of the main frame 1, and a support platform 31 is located at the top of the lifting mechanism 3. The cell factory 6 is placed on the support platform 31. The top surface of the main frame 1 has focusing and moving mechanisms 4 located on the left and right sides of the support platform 31, respectively. The microscope observation module 5 is installed above the focusing and moving mechanisms 4. The system also includes a display control module 7. The display control module 7 is electrically connected to the lifting mechanism 3, the front-to-back translation mechanism 2, the focusing and moving mechanism 4, and the microscope observation module 5. It is used to adjust the front-to-back and vertical positions of the cell factory 6 and the horizontal positions of the microscope observation module 5, and to display and store images and / or video data captured by the microscope observation module 5.

[0031] Preferably, the microscope observation module 5 is as follows: Figure 3As shown, including camera 51, microscope 52 and light source 53, the camera 51 is provided at the rear end of the microscope 52, the light source 53 is provided at the front end of the microscope 52; camera 51 for cell factory inside the cell observation and photography, microscope 52 for cell factory inside the cell observation and adjustment magnification, light source 53 for microscope image observation when light illumination brightness adjustment.

[0032] The focusing movement mechanism 4 as shown Figure 3 As shown, including the bottom plate 41, guide rail module 42, bottom plate 41 installed in the top surface of the main frame 1, guide rail module 42 is installed on the bottom plate 41, guide rail module 42 on the installation of support plate base 43, support plate base 43 is connected to the support connecting plate 44, support connecting plate 44 is provided with support plate 45, support plate 45 for installing microscope observation module 5. Guide rail module 42 drive microscope observation module 5 left and right movement, realize the adjustment of the magnification of the microscope, complete the microscope focusing.

[0033] Further, the front and rear translation mechanism 2 as shown Figure 4 , Figure 5 As shown, including front and rear translation module 21, front and rear translation module 21 is installed on the fixed plate 22 provided in the main frame, the upper of front and rear translation module 21 installation lifting mechanism 3, lifting mechanism 3 includes lifter 32, the upper of front and rear translation module 21 is installed with lifter fixed plate 33, the lower end of lifter 32 is installed on the lifter fixed plate 33 through the lower connecting plate 34, the top of lifter 32 is installed through the upper connecting plate 38 support platform 31. Front and rear translation module 21 drive lifting mechanism 3 as a whole to do front and rear translation movement, in turn drive the cell factory on the support platform 31 front and rear translation movement, lifting mechanism 3 drive cell factory up and down movement. Further, the lifting mechanism 3 also includes lifter shroud outer sleeve 35, lifter shroud inner sleeve 36, the lifter shroud inner sleeve 36 is provided on the outer periphery of the lifter 32, the bottom is connected to the lower connecting plate 34, the outer periphery of the lifter shroud outer sleeve 35 is fixedly connected with the main frame 1, the gap is provided between the lifter shroud outer sleeve 35 and the lifter shroud inner sleeve 36, the lifter 32 and the lifter shroud inner sleeve 36 can move forward and backward in the lifter shroud outer sleeve 35; also includes the concertina cover 37, the concertina cover 37 is two pieces, respectively provided on both sides of the lifter 32, the concertina cover 37 is provided in the lower part of the lifter shroud outer sleeve 35, one end of the concertina cover 37 is connected with the outer wall of the lifter shroud inner sleeve 36, the other end is connected with the inner wall of the main frame 1, used to block the front and rear translation module 21 from the top, when the front and rear translation module 21 drive lifter 32 together to do front and rear linear movement, the concertina cover 37 is stretched or compressed, so that the front and rear translation module 21 is always covered, to avoid dust falling into the front and rear translation module. Preferably, at least one corner of the support platform 31 is provided with a positioning block 311, the positioning block 311 is preferably "L" type, used to limit the placement position of the cell factory.

[0034] Further, the display control module 7 is arranged on the top surface of the main frame 1, and comprises a human-computer interaction control unit 71 and a computer display unit 72; the human-computer interaction control unit 71 is preferably an HMI touch screen, and is used for human-computer interaction control of the operation of the device and the adjustment of system parameters; the human-computer interaction control unit 71 further comprises a power switch 73, a light source adjustment switch 74, an emergency stop button 75 and the like, and is used for the power on and off of the system; the computer display unit 72 is preferably a notebook computer, and is connected with the data interface of the camera 51 of the microscope observation module 5 through a USB interface; the computer display unit 72 is integrated with an observation software, and the internal observation of the cell factory and the photographing or video shooting of the observation image are realized through the observation software.

[0035] Further, as shown in Figure 1 , the main frame 1 is provided with an electrical control chamber 13, and the electrical control chamber 13 is arranged at the lower part of the display control module 7; the electrical control chamber 13 is integrated with the core electrical control of the system; preferably, the main frame 1 is provided with supporting legs 11 at the four corners of the bottom, and is further provided with universal casters 12, so as to facilitate the overall movement.

[0036] The cell factory microscopic observation system of the utility model, the front and back translation mechanism drives the cell factory to move forward and backward to realize observation of different parts, and the contrastive diagram of the front and back translation mechanism moving forward and backward is as shown in Figure 7 ; the cell factory can be moved up and down through the lifting mechanism, the upper layer liquid-free area observation and the lower layer liquid area observation of the cell factory can be realized, and the contrastive diagram is as shown in Figure 8 , Figure 9 ; the focusing movement mechanism drives the microscope observation module to move to the observation layer, fine focusing is realized through the focusing movement mechanism, clear images can be seen on the observation software of the computer display unit, and photographing or video shooting is realized for internal data storage backup; meanwhile, the light source can be turned on, the light brightness is adjusted, the photographing reaches clear images, and the contrastive diagram of the microscope observation module moving forward and backward is as shown in Figure 6 . The user can view the cell image through the computer display unit, and can adjust parameters and operate according to the observation needs. For example, when the cell growth is found to be abnormal, the environmental parameters can be adjusted in time or other measures can be taken.

[0037] Of course, the utility model also has other various embodiments, and the skilled in the art can make various corresponding changes and modifications according to the utility model without departing from the spirit and essence of the utility model; however, these corresponding changes and modifications should all belong to the protection scope of the claims attached to the utility model.

Claims

1. A cell factory microscopic observation system characterized by comprising: The utility model relates to a cell factory observation device, including main body frame (1), front and back translation mechanism (2), lifting mechanism (3), focus movement mechanism (4), microscope observation module (5), the main body frame (1) inside is equipped with front and back translation mechanism (2) from below and upwards, lifting mechanism (3), lifting mechanism (3) penetrates the top surface of main body frame (1), and the top of lifting mechanism (3) is equipped with support platform (31), and cell factory (6) is placed on support platform (31), and the top surface of main body frame (1) is located support platform (31) left and right sides and is equipped with focus movement mechanism (4) respectively, and the upper installation microscope observation module (5) of focus movement mechanism (4), still include display control module (7), display control module (7) electric connection lifting mechanism (3), front and back translation mechanism (2), focus movement mechanism (4) and microscope observation module (5) are used for the regulation and control cell factory (6) front and back, upper and lower positions and the left and right positions of microscope observation module (5) to the display storage data of microscope observation module (5) shooting.

2. The cell factory microscopic observation system according to claim 1, characterized by: The microscope observation module (5) includes a camera (51), a microscope (52) and a light source (53), the camera (51) is arranged at the rear end of the microscope (52), and the light source (53) is arranged at the front end of the microscope (52).

3. The cell- factory microscopic observation system according to claim 1, characterized by: The focus movement mechanism (4) includes a bottom plate (41) and a guide rail module (42), the bottom plate (41) is installed on the top surface of the main body frame (1), the guide rail module (42) is installed on the bottom plate (41), the guide rail module (42) is installed on the support plate base (43), the support plate base (43) is connected to the support connecting plate (44), the support connecting plate (44) is provided with a support plate (45), and the support plate (45) is used for installing the microscope observation module (5).

4. The cell- factory microscopic observation system according to claim 1, characterized by: The front and back translation mechanism (2) includes a front and back translation module (21), the front and back translation module (21) is installed on the fixed plate (22) arranged in the main body frame, and the lifting mechanism (3) is installed above the front and back translation module (21).

5. The cell factory microscopic observation system according to claim 4, characterized by: The lifting mechanism (3) includes a lifter (32), the front and back translation module (21) is provided with a lifter fixing plate (33) above, the lower end of the lifter (32) is installed on the lifter fixing plate (33) through the lower connecting plate (34), and the support platform (31) is installed on the top of the lifter (32) through the upper connecting plate (38).

6. The cell factory microscopic observation system according to claim 5, characterized by: The lifting mechanism (3) further comprises a lifter shroud outer sleeve (35) and a lifter shroud inner sleeve (36), the lifter shroud inner sleeve (36) is sleeved on the outer periphery of the lifter (32) and is connected to the lower connecting plate (34) at the bottom, the lifter shroud outer sleeve (35) is fixedly connected to the outer periphery of the main body frame (1), a gap is provided between the lifter shroud outer sleeve (35) and the lifter shroud inner sleeve (36) in front and back, and the lifter (32) and the lifter shroud inner sleeve (36) can move forward and backward in the lifter shroud outer sleeve (35); the organ case (37) is further provided, the organ case (37) is two pieces and is provided on the front and back sides of the lifter (32), the organ case (37) is provided at the lower part of the lifter shroud outer sleeve (35), one end of the organ case (37) is connected to the outer wall of the lifter shroud inner sleeve (36), and the other end is connected to the inner wall of the main body frame (1).

7. The cell- factory microscopic observation system according to claim 1, characterized by: At least one corner of the support platform (31) is provided with a positioning block (311).

8. The cell factory microscopic observation system according to claim 7, characterized by: At least one of the positioning blocks (311) is in the shape of "L".

9. The cell- factory microscopic observation system according to claim 1, characterized by: The display control module (7) is arranged on the top surface of the main body frame (1) and comprises a human-computer interaction control unit (71) and a computer display unit (72), the human-computer interaction control unit (71) is an HMI touch screen and is used for human-computer interaction control of the operation of the system and the setting and adjustment of system parameters; and the computer display unit (72) is connected to the data interface of the microscope observation module (5) through a USB interface.

10. The cell factory microscopic observation system according to claim 9, characterized by: An electric appliance control chamber (13) is arranged in the main body frame (1), the electric appliance control chamber (13) is arranged below the display control module (7), and support legs (11) and universal casters (12) are arranged at the four corners of the bottom of the main body frame (1).

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