Online sampling and detecting device for anti-cancer drug additive

Abstract

The utility model discloses an anti-cancer drug assistant on-line sampling detection device which comprises a pretreatment tank, a tank cover is fixedly connected above the pretreatment tank, a servo motor is mounted above the tank cover, a bearing plate is mounted below the tank cover, driving teeth are mounted below the bearing plate, a rotating rod is rotationally connected to the other end of the lower portion of the bearing plate, and the rotating rod is rotationally connected to the other end of the lower portion of the bearing plate. One end of the rotating rod is fixedly connected with driven teeth, and the other end of the rotating rod is fixedly connected with a stirring paddle; the filter plates made of three different materials are inserted into the insertion grooves formed in the upper portion of the filter box and respectively contain polyester fibers, polyether sulfone and polyvinylidene fluoride, the filter plates have different pore sizes and filter efficiency, medicine auxiliaries can be filtered step by step, impurities can be effectively removed, and protein can be effectively separated. The quality and the purity of the sample are ensured, and the problem that an existing on-line sampling and detecting device for the anti-cancer drug additive cannot quickly filter out internal protein in the pretreatment process is solved.

Description

TECHNICAL FIELD

[0001] The utility model relates to sampling detection equipment technical field, concretely is an anticancer drug adjuvant on -line sampling detection device. BACKGROUND

[0002] The anticancer drug adjuvant on -line sampling detection device is a kind of equipment specially used in the production process of drug, carries out real-time, on -line sampling and detection to anticancer drug adjuvant, its main function is to ensure the quality stability and safety of drug adjuvant in the production process, and improve the efficiency and accuracy of drug production

[0003] The existing anticancer drug adjuvant on -line sampling detection device cannot quickly filter out internal protein in the pretreatment process, which can cause the subsequent detection process to be interfered by protein, thereby affecting the accuracy and sensitivity of detection, protein is an important component in vivo, but in the detection of anticancer drug adjuvant, they are often regarded as interfering substances, because they can mask or interfere with the signal of target drug, secondly, since protein cannot be quickly filtered, the entire pretreatment process can become lengthy and complex, which is not conducive to realizing rapid, efficient on -line detection, in the modern drug research and production process, time is a very valuable resource, therefore, a device that can quickly and accurately complete pretreatment and detection is essential to improve production efficiency. SUMMARY

[0004] The utility model aims at: in order to solve the above-mentioned problem, provide a kind of anticancer drug adjuvant on -line sampling detection device.

[0005] To achieve the above object, the utility model provides the following technical scheme: a kind of anticancer drug adjuvant on -line sampling detection device, comprising: pretreatment tank, the pretreatment tank upper side is fixedly connected with tank cover, the tank cover upper side is installed with servo motor, the tank cover lower side is installed with receiving plate, the receiving plate lower side is installed with driving tooth, the receiving plate lower side another end is connected with rotating rod, the rotating rod one end is fixedly connected with driven tooth, the rotating rod another end is fixedly connected with stirring paddle, the pretreatment tank inside is fixedly connected with broken paddle, the receiving plate side is fixedly connected with scraping edge plate, the scraping edge plate side is fixedly connected with soft rubber scraper, the pretreatment tank lower side is fixedly connected with hopper.

[0006] As a further scheme of the utility model: the hopper lower side is fixedly connected with filter box, the filter box upper side is provided with slot, the slot inside is inserted with filter plate, the slot and the filter plate number are all provided with three groups, and three groups of filter plate inside are respectively provided with polyester fiber, polyether sulfone and polyvinylidene fluoride.

[0007] As a further scheme of the utility model: the fixed sleeve below is fixedly connected with supporting legs, and the tank cover is provided with a feeding opening above.

[0008] As a further scheme of the utility model: the servo motor is connected with the receiving plate and the driving tooth, the driving tooth is matched with the driven tooth, and the rotating rod, the driven tooth, the stirring paddle and the scraping plate are all provided with three groups.

[0009] As a further scheme of the utility model: the filter box is provided with a valve at one end of the pipeline connected with the discharge hopper.

[0010] As a further scheme of the utility model: the supporting legs are provided with three groups, which are symmetrically arranged at three ends below the fixed sleeve, and the feeding opening penetrates the tank cover.

[0011] Compared with the prior art, the utility model has the beneficial effects that:

[0012] In the utility model, three kinds of filter plates with different materials are inserted into the slots arranged above the filter box, which respectively contain polyester fiber, polyether sulfone and polyvinylidene fluoride, and the filter plates have different pore sizes and filtering efficiencies, can filter the drug adjuvant step by step, effectively remove impurities and separate proteins, ensure the quality and purity of the sample, and improve the problem that the existing online sampling detection device for anticancer drug adjuvant cannot quickly filter the internal proteins in the pretreatment process. BRIEF DESCRIPTION OF DRAWINGS

[0013] Figure 1 is the overall structure schematic view of the online sampling detection device for anticancer drug adjuvant.

[0014] Figure 2 is the internal structure schematic view of the online sampling detection device for anticancer drug adjuvant.

[0015] Figure 3 is the structure schematic view of the separation mechanism in the online sampling detection device for anticancer drug adjuvant.

[0016] Figure 4 is the structure schematic view of the filter box in the online sampling detection device for anticancer drug adjuvant.

[0017] In the figure: 1, pre-treatment tank; 2, tank cover; 3, servo motor; 4, receiving plate; 5, driving tooth; 6, rotating rod; 7, driven tooth; 8, stirring paddle; 9, crushing paddle; 10, edge scraping plate; 11, soft glue scraper; 12, discharge hopper; 13, filter box; 14, insertion slot; 15, filter plate; 16, polyester fiber; 17, polyether sulfone; 18, polyvinylidene fluoride; 19, fixing sleeve; 20, supporting leg; 21, feeding port. DETAILED DESCRIPTION

[0018] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.

[0019] With reference to Figures 1 to 4 In the embodiments of the utility model, an online sampling and detecting device for anticancer drug adjuvant comprises a pre-treatment tank 1, a tank cover 2 is fixedly connected above the pre-treatment tank 1, a servo motor 3 is installed above the tank cover 2, a receiving plate 4 is installed below the tank cover 2, a driving tooth 5 is installed below the receiving plate 4, a rotating rod 6 is connected to the other end below the receiving plate 4, a driven tooth 7 is fixedly connected to one end of the rotating rod 6, a stirring paddle 8 is fixedly connected to the other end of the rotating rod 6, a crushing paddle 9 is fixedly connected inside the pre-treatment tank 1, an edge scraping plate 10 is fixedly connected to the side of the receiving plate 4, a soft glue scraper 11 is fixedly connected to the side of the edge scraping plate 10, a discharge hopper 12 is fixedly connected below the pre-treatment tank 1, the servo motor 3 is connected with the receiving plate 4 and the driving tooth 5, the driving tooth 5 is adapted to the driven tooth 7, the number of the rotating rod 6, the driven tooth 7, the stirring paddle 8 and the edge scraping plate 10 is all set to three groups, the anticancer drug adjuvant is put into the pre-treatment tank 1 through the feeding port 21 above the tank cover 2, after the servo motor 3 is started, the driving tooth 5 is driven to rotate through the connecting device, the driving tooth 5 is engaged with the driven tooth 7, thereby driving the rotating rod 6 and the stirring paddle 8 at the end of the rotating rod 6 to rotate, the rotation of the stirring paddle 8 promotes the uniform mixing of the drug adjuvant in the pre-treatment tank 1, at the same time, the crushing paddle 9 fixedly connected inside the pre-treatment tank 1 preliminarily crushes the large solid in the adjuvant, ensuring the smoothness of the subsequent processing, then the receiving plate 4 is rotated, the edge scraping plate 10 fixedly connected to the side of the receiving plate 4 and the soft glue scraper 11 thereon are driven, with the rotation of the receiving plate 4, the adjuvant adhered to the inner wall of the pre-treatment tank 1 is scraped and cleaned, preventing the uneven processing caused by the residue of the material.

[0020] With reference to Figure 1 And Figure 4The lower part of the hopper 12 is fixedly connected with a filter box 13, the upper part of the filter box 13 is provided with a slot 14, the slot 14 is inserted with a filter plate 15, the number of the slot 14 and the filter plate 15 is three groups, and the three groups of filter plates 15 are respectively provided with polyester fiber 16, polyether sulfone 17 and polyvinylidene fluoride 18, one end of the pipeline connected with the filter box 13 and the lower hopper 12 is provided with a valve, the slot 14 provided on the upper part of the filter box 13 is inserted with three kinds of filter plates 15 of different materials, which respectively contain polyester fiber 16, polyether sulfone 17 and polyvinylidene fluoride 18, these filter plates 15 have different pore sizes and filtering efficiency, which can filter the drug adjuvant step by step, effectively remove impurities and separate proteins, ensure the quality and purity of the sample, according to the specific characteristics and detection requirements of anticancer drug adjuvant, different materials and filtering levels of filter plates 15 can be selected, the design of the slot 14 facilitates the quick replacement or adjustment of the filter plate 15, improves the flexibility and applicability of the device.

[0021] With reference to Figures 1 to 2 The side of the pretreatment tank 1 is fixedly connected with a fixed sleeve 19, the lower part of the fixed sleeve 19 is fixedly connected with a support leg 20, the upper part of the tank cover 2 is provided with a feeding port 21, the number of the support leg 20 is three groups, which are symmetrically arranged at the three ends below the fixed sleeve 19, and the feeding port 21 penetrates the tank cover 2, the fixed sleeve 19 fixedly connected with the side of the pretreatment tank 1 and the support leg 20 below it jointly constitute the stable support structure of the device, which ensures the stable operation of the device during stirring, crushing and filtering, and the three groups of support legs 20 are symmetrically arranged at the three ends below the fixed sleeve 19, which enhances the overall balance and stability.

[0022] Meanwhile, the contents not described in detail in the specification all belong to the existing technology known to those skilled in the art.

[0023] The working principle of the utility model is: firstly, anticancer drug adjuvant is put into the pretreatment tank 1 through the feeding port 21 on the tank cover 2, after the servo motor 3 is started, the driving gear 5 is driven to rotate through the connecting device, the driving gear 5 is engaged with the driven gear 7, thereby driving the rotating rod 6 and the stirring paddle 8 at the end thereof to rotate, the rotation of the stirring paddle 8 promotes the uniform mixing of the drug adjuvant in the pretreatment tank 1, at the same time, the crushing paddle 9 fixedly connected in the pretreatment tank 1 preliminarily crushes the large solid in the adjuvant, ensures the smoothness of subsequent processing, then the rotary receiving plate 4 is rotated, the scraping edge plate 10 and the soft rubber scraper 11 thereon fixedly connected on the side surface thereof are driven, with the rotation of the receiving plate 4, the adjuvant adhered to the inner wall of the pretreatment tank 1 is scraped and cleaned, prevents uneven processing caused by material residue, after the pretreatment is completed, the drug adjuvant is guided to the filter box 13 through the discharge hopper 12 below the pretreatment tank 1, a valve is installed on the pipeline between the discharge hopper 12 and the filter box 13, is used for controlling the flow and opportunity of discharging, the insertion slot 14 is formed in the upper portion of the filter box 13, three different material filter plates 15 are inserted therein, containing polyester fiber 16, polyether sulfone 17 and polyvinylidene fluoride 18 respectively, these filter plates 15 have different pore sizes and filtering efficiencies, can filter the drug adjuvant gradually, effectively removes impurities and separates proteins, ensures the quality and purity of the sample, according to the specific characteristics and detection requirements of the anticancer drug adjuvant, different material and filtering level filter plates 15 can be selected and used, the insertion slot 14 is designed to facilitate the quick replacement or adjustment of the filter plate 15, improves the flexibility and applicability of the device, the fixing sleeve 19 fixedly connected on the side surface of the pretreatment tank 1 and the support leg 20 below jointly constitute the stable support structure of the device, ensures the stable operation of the device during stirring, crushing and filtering, three groups of support legs 20 are symmetrically arranged at three ends below the fixing sleeve 19, enhance the balance and stability of the whole.

[0024] The above is only the preferred specific embodiment of the utility model, but the protection scope of the utility model is not limited to this, any skilled person in the art can make equivalent replacement or change according to the technical scheme and the utility model concept of the utility model within the technical range disclosed by the utility model, all should be covered in the protection scope of the utility model.

Claims

1. An anticancer drug aid online sampling detection device, characterized by, Include: Preprocessing tank (1), the preprocessing tank (1) is fixedly connected with the tank cover (2) above, the tank cover (2) is installed with servo motor (3) above, the tank cover (2) is installed with the receiving plate (4) below, the receiving plate (4) is installed with the driving gear (5) below, the receiving plate (4) is connected with the rotating rod (6) on the other end below, the rotating rod (6) one end is fixedly connected with the driven gear (7), the rotating rod (6) the other end is fixedly connected with the stirring paddle (8), the preprocessing tank (1) is fixedly connected with the crushing paddle (9) inside, the receiving plate (4) side is fixedly connected with the scraping edge plate (10), the scraping edge plate (10) side is fixedly connected with the soft rubber scraper (11), the preprocessing tank (1) is fixedly connected with the lower hopper (12) below; The lower hopper (12) is fixedly connected with the filter box (13) below, the filter box (13) is provided with the slot (14) above, the slot (14) is inserted with the filter plate (15), the slot (14) and the filter plate (15) are provided with three groups, and three groups of the filter plate (15) are respectively provided with polyester fiber (16), polyether sulfone (17) and polyvinylidene fluoride (18).

2. The online sampling and detecting device for an anticancer drug adjuvant according to claim 1, characterized in that, The preprocessing tank (1) side is fixedly connected with the fixed sleeve (19), the fixed sleeve (19) is fixedly connected with the supporting leg (20) below, the tank cover (2) is provided with the feeding port (21) above.

3. The online sampling and detecting device for an anticancer drug adjuvant according to claim 1, characterized in that, The servo motor (3) is connected with the receiving plate (4) and the driving gear (5), the driving gear (5) is matched with the driven gear (7), the rotating rod (6), the driven gear (7), the stirring paddle (8) and the scraping edge plate (10) are provided with three groups.

4. The online sampling and detecting device for an anticancer drug adjuvant according to claim 1, characterized in that, The pipeline, which is connected with the filter box (13) and the lower hopper (12), is provided with a valve at one end.

5. The online sampling and detecting device for an anticancer drug adjuvant according to claim 2, characterized in that, The supporting leg (20) is provided with three groups, which are symmetrically arranged below the fixed sleeve (19), and the feeding port (21) penetrates the tank cover (2).

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