Universal sample adding indicator

Abstract

The utility model relates to a universal sample adding indicator. The universal sample adding indicator comprises a base; the material plate comprises a base plate and at least three overturning plates, the base plate is rotationally connected to the base, the multiple overturning plates are circumferentially distributed on the base plate, and the overturning plates and the base plate within the surrounding range of the overturning plates form a material carrying part. The material plate can be loaded with a pore plate for sample adding, and the material plate can rotate relative to the base, so that the angle of the pore plate on the material plate is adjusted, the distance difference between each pore position of the pore plate and an operator is reduced, the operator is clear in sight during sample adding, visual fatigue is relieved, and the conditions of wrong adding and missing adding can be avoided.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of medical devices, in particular to a universal sample adding indicator. BACKGROUND

[0002] In the field of sample adding technology, a 96-well plate is commonly used in laboratory detection. In order to improve the accuracy of sample adding, an auxiliary indicator needs to be used due to the large number of sample adding holes on the same plate. In the existing auxiliary indicator scheme, the light signal of an LED lamp group is used as an indicator for distinguishing the positions of the sample adding holes.

[0003] However, in the process of use, in order to ensure the safety of the operator and prevent the operator from being threatened by infectious samples, the sample adding operation needs to be strictly required to be performed in a biological safety cabinet or a super-clean bench, which results in that the operator needs to operate through the glass, so that the plate is at a certain distance from the operator, and due to the visual angle problem, multiple LED lamps are arranged in a gradually away from the operator manner in front of the operator. Due to the arrangement manner and the imaging of the eyes, it is difficult to distinguish the positions of the sample adding holes according to the LED lamps in the face of the dense LED lamps. CONTENT OF THE UTILITY MODEL

[0004] In order to solve the above technical problems, the present application provides the following technical solutions:

[0005] A universal sample adding indicator, comprising:

[0006] a base; and

[0007] a material plate, the material plate comprising a base plate and at least three turnover plates, the base plate being rotationally connected to the base, and the plurality of turnover plates being circumferentially distributed on the base plate, and the turnover plate and the base plate within the surrounding range of the turnover plate forming a material loading part.

[0008] In one embodiment, the material plate can be rotated to a first working position or a second working position relative to the base;

[0009] When the material plate is in the first working position, the material plate is attached to the base;

[0010] When the material plate is in the second working position, the material plate is inclined relative to the base.

[0011] In one embodiment, a damper is provided between the material plate and the base.

[0012] In one embodiment, a support column is rotationally connected to the material plate, and when the material plate is in the second working position, the support column is supported between the material plate and the base.

[0013] In one embodiment, a plurality of clamping grooves are formed on the base at intervals, and one end of the support column is inserted into any clamping groove.

[0014] In one of the embodiments, a top surface of the base is provided with a receiving groove matched with the sample plate, and the sample plate is embedded in the receiving groove when the sample plate is in the first working position.

[0015] In one of the embodiments, the base plate is provided with a clearance groove matched with the turnover plate, and the turnover plate is pivotally connected to the inner wall of the clearance groove.

[0016] In one of the embodiments, the turnover plate can be turned to a storage position and a stop position relative to the base plate.

[0017] When the turnover plate is in the storage position, the highest surface of the turnover plate is flush with the upper surface of the base plate.

[0018] When the turnover plate is in the stop position, the turnover plate protrudes from the upper surface of the base plate.

[0019] In one of the embodiments, the adjacent two turnover plates are provided with indicator lights.

[0020] When the turnover plate is in the storage position, the indicator light faces the inner wall of the clearance groove.

[0021] When the turnover plate is in the stop position, the indicator light faces upward.

[0022] In one of the embodiments, the base is further provided with a plurality of display modules.

[0023] In one of the embodiments, a spacer plate with the same size as the sample loading part and different height is provided, when a low 96-hole plate (low thickness) is used, the spacer plate can be placed on the sample loading part, and the height of the hole plate is raised to the height of the sample loading part, so that the height of the hole plate and the indicator is equivalent, and the adaptability of the indicator to various 96-hole plates is increased.

[0024] The present application has at least the following beneficial effects:

[0025] In the present application, the hole plate can be loaded on the sample plate, and the sample plate can be rotated relative to the base, so that the angle of the hole plate on the sample plate is adjusted, the distance difference between the holes of the hole plate and the operator is reduced, the operator's vision is clear during sample loading, visual fatigue is reduced, and the situation of wrong or missed sample loading can be avoided. BRIEF DESCRIPTION OF DRAWINGS

[0026] Figure 1 FIG. 1 is a perspective view of a sample loading indicator provided by Embodiment One of the present application, in which the sample plate is in the first working position and the turnover plate is in the storage position.

[0027] Figure 2 FIG. 2 is a perspective view of the sample loading indicator provided by Embodiment One of the present application, in which the sample plate is in the second working position and the turnover plate is in the stop position. FIG. 3 is a perspective view of the sample loading indicator provided by Embodiment Two of the present application, in which the sample plate is in the first working position and the turnover plate is in the storage position.

[0028] Figure 3 The perspective view of the sample plate of the sample adding indicator provided in Embodiment One of the present application is in the first working position and the turnover plate is in the storage position.

[0029] Figure 4 The perspective view of the sample plate of the sample adding indicator provided in Embodiment One of the present application is in the first working position and the turnover plate is in the stop position.

[0030] Figure 5 The distribution of the turnover plate provided in Embodiment One of the present application.

[0031] Figure 6 The perspective view of the sample adding indicator provided in Embodiment Two of the present application.

[0032] Figure 7 The exploded view of the sample adding indicator provided in Embodiment Two of the present application.

[0033] Reference signs:

[0034] 11, sample plate; 12, base; 13, display module; 14, sample loading part; 15, pad plate;

[0035] 111, base plate; 112, turnover plate; 113, support column;

[0036] 1111, upper surface; 1112, accommodation groove;

[0037] 1121, first side surface; 1122, second side surface; 1123, indicator lamp;

[0038] 121, top surface; 122, accommodation groove; 123, clamping groove; 124, slope. DETAILED DESCRIPTION

[0039] In order to make the purpose, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be described clearly and completely below in combination with the drawings of the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, rather than all the embodiments. Based on the described embodiments of the present application, all other embodiments obtained by those skilled in the art belong to the scope of protection of the present application.

[0040] Unless otherwise defined, technical terms or scientific terms used in the present application shall have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. Unless otherwise defined, the technical terms or scientific terms used in the present application shall have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terms "first", "second", and similar terms are not intended to denote any order, quantity, or importance, but are used to distinguish different components. Similarly, the terms "one" or "a" or similar terms do not denote a quantity limitation, but denote the presence of at least one. The terms "connected" or "connected" or similar terms are not limited to physical or mechanical connections, but can include electrical connections, whether direct or indirect. The terms "up", "down", "left", "right", and the like are used only to represent relative positional relationships, and when the absolute positions of the described objects are changed, the relative positional relationships are also changed accordingly.

[0041] The embodiments of the present application will be described in detail below with reference to the accompanying drawings.

[0042] Reference Figures 1-4 As shown, the embodiments of the present application provide a general-purpose sample adding indicator, which comprises a base 12 and a plate 11, and the base 12 and the plate 11 are rotationally connected. Wherein, the plate 11 comprises a base plate 111 and at least three turnover plates 112, the base plate 111 is rotationally connected to the base 12, and a plurality of turnover plates 112 are circumferentially distributed on the base plate 111, and the turnover plate 112 and the base plate 111 within the surrounding range of the turnover plate 112 form a loading part 14. The loading part 14 is used to load a hole plate, and the position of the hole plate is limited by the turnover plate 112. Specifically, the hole plate is placed on the upper surface 1111 of the base plate 111, and the turnover plate 112 is located on the upper surface 1111. For example, the hole plate is rectangular, and the number of turnover plates 112 is four, and the four turnover plates 112 correspond to the four sides of the hole plate one by one.

[0043] In the present scheme, the plate 11 can rotate relative to the base 12, so that the hole plate loaded on the plate 11 can be adjusted relative to the base 12. Since the position of the base 12 is relatively unchanged, the hole plate view angle changes in the eyes of the operator. The sample adding holes on the hole plate that are far away from the operator will be reduced in the field of view of the operator, and due to the angle of view, multiple hole positions in the same horizontal plane will cause the operator to visually fatigue and affect the accuracy of sample adding. The change of the hole plate view angle reduces the distance difference between each hole position of the hole plate and the operator, the base 12 is always located on the horizontal plane, and the rotating plate 11 gradually approaches the vertical plane, at this time, the distance between each point of the plate 11 and the operator tends to be consistent. Further, when sample adding, the operator's line of sight is clear, which reduces visual fatigue and can avoid the situation of wrong or missed sample adding.

[0044] In the scheme, the material plate 11 can be rotated to a first working position or a second working position relative to the base 12. Specifically, when the material plate 11 is in the first working position, the material plate 11 is attached to the base 12, at this time, the material plate 11 is located on the horizontal plane; when the material plate 11 is in the second working position, the material plate 11 is inclined relative to the base 12, and the material plate 11 forms an angle with the horizontal plane.

[0045] In a specific embodiment, the material plate 11 is connected with a support column 113, when the material plate 11 is in the second working position, the support column 113 is supported between the material plate 11 and the base 12. The support column 113 forms a triangular structure with the surface of the material plate 11 and the base 12, thereby ensuring the stability of the material plate 11 in the second working position. In the scheme, the material plate 11 is rotatably connected with the support column 113, specifically, one end of the support column 113 is pivoted to the material plate 11, so that the support column 113 can be attached to the material plate 11, thereby reducing the storage area of the material plate 11.

[0046] Further, the base 12 is provided with a plurality of spaced-apart clamping grooves 123, and the other end of the support column 113 is inserted into any clamping groove 123. In the scheme, the arrangement direction of the clamping grooves 123 is perpendicular to the rotation axis of the material plate 11. By the support column 113 and any clamping groove 123, the angle between the material plate 11 and the base 12 can be adjusted.

[0047] It can be understood that the way to keep the angle between the material plate 11 and the base 12 fixed includes but is not limited to supporting and fixing by the support column 113. The way to keep the angle between the material plate 11 and the base 12 fixed can also be provided with a damper between the material plate 11 and the base 12. By the friction force of the damper, the material plate 11 can be kept hovering at any angle when it is inclined relative to the base 12.

[0048] Further, the top surface 121 of the base 12 is provided with a receiving groove 122 matched with the material plate 11, and the material plate 11 is pivoted to the inner wall of the receiving groove 122. When the material plate 11 is in the first working position, the material plate 11 is embedded in the receiving groove 122. Specifically, when the material plate 11 is in the first working position, the upper surface 1111 is flush with the top surface 121 of the base 12, so that the sample adding indicator is more beautiful. At the same time, the clamping grooves 123 are provided on the groove bottom surface of the receiving groove 122. The base 12 is built-in with a high-sensitivity gravity sensor, which is used to detect the overall gravity change of the material plate 11.

[0049] In some embodiments of the present application, the flip plate 112 is rotatably connected to the base plate 111. Specifically, the base plate 111 is provided with a clearance slot 1112 matched with the flip plate 112, and the flip plate 112 is pivotally connected to the inner wall of the clearance slot 1112. The flip plate 112 can be flipped relative to the base plate 111 to a storage position and a stop position, and the flip plate 112 has a first side 1121. When the flip plate 112 is located at the storage position, the highest surface of the flip plate 112 is flush with the upper surface 1111 of the base plate 111, i.e., the first side 1121 is flush with the upper surface 1111. When the flip plate 112 is located at the stop position, the flip plate 112 protrudes from the upper surface 1111 of the base plate 111, i.e., the first side 1121 is arranged perpendicularly to the upper surface 1111.

[0050] In the present scheme, the flip plate 112 can be turned into the clearance slot 1112, so that the flip plate 112 forms an integral with the base plate 111. More specifically, the two adjacent flip plates 112 are provided with indicator lights 1123, which are used as indicators for identifying the positions of the sample wells. When the flip plate 112 is located at the storage position, the indicator light 1123 faces the inner wall of the clearance slot 1112. When the flip plate 112 is located at the stop position, the indicator light 1123 faces upward.

[0051] The flip plate 112 also has a second side 1122 adjacent to the first side 1121. When the flip plate 112 is located at the storage position, the first side 1121 is arranged upward. When the flip plate 112 is located at the stop position, the second side 1122 is arranged upward. The indicator light 1123 is arranged on the second side 1122. When the flip plate 112 is located at the storage position, the indicator light 1123 is hidden, thereby protecting the indicator light 1123 when not in use.

[0052] Since the sample wells on the hole plate are arranged in an array. For example, the use method of the indicator light 1123 is that the indicator light 1123 on one flip plate 112 indicates the horizontal position, and the indicator light 1123 on the other flip plate 112 indicates the vertical position. Through the indicator lights 1123 on the two flip plates 112, the position of a specified hole on the hole plate can be located.

[0053] Compared with the existing method of using LED light groups to indicate at the bottom of each sample well by light signals, the indicator light 1123 in the present scheme can be compatible with more sample extraction reagents. Many extraction reagents have been integrated into 96-well sample plates, such as the most commonly used magnetic bead method. The magnetic beads are pre-installed in the sample plate, and the black hole bottom cannot transmit light. The existing LED light group cannot be applied to the bottom of each sample well. In the present application, since the indicator light 1123 is arranged on the flip plate 112 for positioning the hole plate, the compatibility of the sample indicator is better.

[0054] Further, referring to Figure 5 As shown in the drawings, the flip plate 112 is provided with markings, and the indicator lights 1123 are arranged on the same side of the flip plate 112, and the indicator lights 1123 are arranged one by one corresponding to the markings. For example, the indicator lights 1123 matched with the upper row of the sample plate are marked with numbers 1-12, and the indicator lights 1123 matched with the upper column of the sample plate are marked with letters A-H.

[0055] In some embodiments of the present application, the base 12 is further provided with a plurality of display modules 13. Specifically, the display module 13 includes two display screens, one display screen is used to select the sample adding mode and display the sample adding position, specifically, the display screen can select the working mode (manual sample adding / automatic sample adding). The other display screen is used to select the sample adding mode, specifically, the display screen can select the sample adding mode (horizontal single hole, horizontal single row, vertical single hole, vertical single column). The display screen can select the mode can adopt a touch screen, or a display screen and an option button.

[0056] In the present scheme, the base 12 is further provided with a slope 124, the slope surface is inclined relative to the top surface 121, and the display module 13 is installed on the slope 124, so that the inclination angle of the display module 13 is convenient for the operator to view.

[0057] Further, the slope 124 is close to the side of the sample plate 11 and the pivot joint of the base 12. Specifically, the high side of the slope 124 is close to the side of the sample plate 11 and the pivot joint of the base 12. For example, when the sample plate 11 is in the second working position, the slope surface is approximately parallel to the sample plate 11, so that the operator can conveniently observe the display module 13 and the hole plate at the same time.

[0058] In some embodiments of the present application, the sample adding indicator positioning mode, the indicator lights 1123 on the adjacent two flip plates 112 are matched with the row and column of the sample plate, that is, the indicator lights 1123 on one flip plate 112 are arranged one by one corresponding to the hole position of the row, and the indicator lights 1123 on the other flip plate 112 are arranged one by one corresponding to the hole position of the column, and the working mode of the sample adding indicator is specifically:

[0059] Manual sample adding mode: due to the sensitivity of gravity sensing, it is recommended to select this mode when the sample amount to be added is below 100ul or when manual sample adding is habitual. Specifically, each time a sample is added, the sample adding position is displayed by manually pressing a button to indicate that the sample adding is completed, and the specific indicator lights 1123 on the adjacent two flip plates 112 are turned on to indicate the next sample adding position.

[0060] Automatic sample adding mode: in view of the sensitivity of gravity sensor, it is suggested that the sample amount added is more than 100ul, and the mode is used, specifically, the gravity sensor at the bottom of the indicator senses the stable increase of the gravity of the whole sample adding plate, indicating the completion of one-time adding, the display screen shows the adding position, and the specific indicator light 1123 on the adjacent two flip plates 112 is turned on to indicate the next adding position.

[0061] Horizontal single-hole mode: the adding sequence is A1, A2, A3, A4...A12; B1, B2...B12, the display sequence of the position on the display screen is as shown above, and the turning-on sequence of the indicator light 1123 on the adjacent two flip plates 112 is the same.

[0062] Horizontal single-row mode: when using the row gun to add samples to a row of sample holes horizontally, the display sequence of the position on the display screen is A, B, C, D...H, and the turning-on sequence of the indicator light 1123 on the adjacent two flip plates 112 is that all the 1-12 are turned on first and then all the adding is completed, the A hole light is turned on before the first adding, the B hole light is turned on when the adding is completed and the second adding is entered, the C hole light is turned on when the adding is completed and the third adding is entered, and so on until the H light is turned on.

[0063] Vertical single-hole mode: the adding sequence is A1, B1, C1...H1; A2, B2,..., H12,..., the display sequence of the position on the display screen is as shown above, and the turning-on sequence of the indicator light 1123 on the adjacent two flip plates 112 is the same.

[0064] Vertical single-column mode: when using the row gun to add samples to a column of sample holes vertically, the display sequence of the position on the display screen is 1, 2, 3, 4...12, and the turning-on sequence of the indicator light 1123 on the adjacent two flip plates 112 is that all the A-H are turned on first and then all the adding is completed, the 1 hole light is turned on before the first adding, the 2 hole light is turned on when the adding is completed and the second adding is entered, the 3 hole light is turned on when the adding is completed and the third adding is entered, and so on until the 12 hole light is turned on.

[0065] Because the thicknesses of different types of 96-hole plates are different, when the 96-hole plates of different thicknesses are loaded into the loading part, the distances from the hole plates to the surface where the turned-on indicator light 1123 is located are also different, which affects the position correspondence between the indicator light 1123 and the 96-hole plate. In the present scheme, as shown in FIGS. 1 and 2, a spacer plate 15 with the same size as the loading part 14 and different heights is provided, when a low 96-hole plate (low thickness) is used, the spacer plate can be placed in the loading part 14, and the height of the spacer plate is higher than that of the loading part 14, so that the distance from the surface where the 96-hole plate is located to the indicator light 1123 is kept consistent, and the adaptability of the indicator to various 96-hole plates is increased. Figure 6 、 7

[0066] ​The above examples are used to further illustrate the present application, but do not limit the present application to these specific embodiments. Any modification, equivalent replacement and improvement made within the spirit and principle of the present application should be understood as within the protection scope of the present application.

Claims

1. A universal sample application indicator, comprising: The utility model relates to a material loading platform, which comprises: a base (12); and a material plate (11) comprising a base plate (111) pivotally connected to the base (12) and at least three turnover plates (112) circumferentially distributed on the base plate (111), the turnover plates (112) and the base plate (111) within the range of the turnover plates (112) forming a material loading part (14).

2. The sample application indicator of claim 1, wherein The material plate (11) can be rotated to a first working position or a second working position relative to the base (12); when the material plate (11) is in the first working position, the material plate (11) is attached to the base (12); when the material plate (11) is in the second working position, the material plate (11) is inclined relative to the base (12).

3. The sample application indicator of claim 2, wherein, A damper is arranged between the material plate (11) and the base (12).

4. The sample application indicator of claim 2, wherein, A support column (113) is pivotally connected to the material plate (11), and when the material plate (11) is in the second working position, the support column (113) is supported between the material plate (11) and the base (12).

5. The sample application indicator of claim 4, wherein, A plurality of clamping grooves (123) are arranged on the base (12), and one end of the support column (113) is inserted into any clamping groove (123).

6. The sample application indicator of any one of claims 2-5, wherein, A receiving groove (122) compatible with the material plate (11) is arranged on the top surface (121) of the base (12), and when the material plate (11) is in the first working position, the material plate (11) is embedded in the receiving groove (122).

7. The sample application indicator of any one of claims 1-5, wherein, A clearance groove (1112) compatible with the turnover plate (112) is arranged on the base plate (111), and the turnover plate (112) is pivotally connected to the inner wall of the clearance groove (1112).

8. The sample application indicator of claim 7, wherein, The turnover plate (112) can be flipped to a storage position and a stop position relative to the base plate (111); when the turnover plate (112) is in the storage position, the highest surface of the turnover plate (112) is flush with the upper surface (1111) of the base plate (111); when the turnover plate (112) is in the stop position, the turnover plate (112) protrudes from the upper surface (1111) of the base plate (111).

9. The sample application indicator of claim 8, wherein, Adjacent two turnover plates (112) are provided with indicator lights (1123); when the turnover plate (112) is in the storage position, the indicator light (1123) faces the inner wall of the clearance groove (1112); when the turnover plate (112) is in the stop position, the indicator light (1123) faces upward.

10. The sample application indicator of any one of claims 1-5, wherein, The base (12) is further provided with a plurality of display modules (13).

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