Automatic pipetting device for radionuclides and liquid medicine

Abstract

The utility model provides an automatic pipetting device for radionuclide and liquid medicine. The automatic pipetting device comprises a transmission assembly, a fixing assembly and a gun head assembly from top to bottom, wherein the fixing assembly comprises a limiting baffle, a piston cylinder body and a fixing seat; the device is controlled by programs, the material quantity can be accurately calculated, and the accuracy of the production process is improved; the pipetting device is used in cooperation with an automatic pipetting mechanism, manual operation is not needed in the whole process, the whole pipetting process is carried out in a closed environment, aerosol leakage is avoided, and the radiation risk of technicians is reduced.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical instrument technical field, in particular to a kind of automatic pipetting device for radionuclide and liquid medicine. BACKGROUND

[0002] Pipetting device is a kind of for quantitative transfer liquid appliance, usually through control module realizes the function of automatic replacement gun head, while combining mobile mechanism to quantitatively suck and transfer liquid. Automatic gun head replacement technology improves experimental efficiency, also significantly improves the safety and accuracy of experiment, reduces the safety risk of laboratory personnel, and helps laboratory to achieve higher safety standards. This design is especially suitable for the process of radionuclide and liquid medicine. UTILITY MODEL CONTENT

[0003] The utility model provides a novel device for radionuclide and liquid medicine automatic pipetting.

[0004] To achieve the above object, the utility model provides the following technical scheme:

[0005] A kind of automatic pipetting device for radionuclide and liquid medicine, from top to bottom including transmission assembly, fixed component and gun head assembly;The fixed component includes limit baffle, piston cylinder and fixed seat;

[0006] Further, the fixed seat is fixed to the outer side of the piston cylinder;The gun head assembly is connected with the limit baffle by guide shaft, and the guide shaft penetrates the fixed seat up and down;The gun head assembly is set on the outer side of the piston cylinder.

[0007] Further, the transmission assembly includes lead screw, motor and piston rod;The upper part of the lead screw is built into the motor, and the lower end of the lead screw is fixed with the piston rod;The piston rod penetrates the limit baffle, and the lower part is located in the cavity of the piston cylinder.

[0008] More further, the top end of the piston rod is platform-shaped, located above the limit baffle;The middle part of the piston rod is provided with recess, and is clamped in the through hole in the center of the limit baffle;The lower part of the piston rod is cylindrical.

[0009] Specifically, the lower part of the piston rod is also provided with rubber ring.

[0010] Preferably, the limit baffle is composed of upper and lower two parts, and the lower part is annular, and the upper part is horseshoe-shaped.

[0011] More preferably, a plurality of guide shaft holes are opened on the limit baffle, which penetrate the upper and lower ends;The hollow structure of the horseshoe-shaped part is matched with the shape and size of the recess in the middle part of the piston rod, and the inner diameter of the annular part is greater than the outer diameter of the cylindrical part of the piston rod;

[0012] Further, the fixed seat is internally provided with a plurality of guide shaft grooves, spring grooves are additionally formed at the top opening of the guide shaft grooves, spring assemblies are installed in the spring grooves, the top end of the spring assemblies is fixed to the bottom of the limiting baffle, and the bottom end of the spring assemblies is arranged at the bottom of the spring grooves.

[0013] Further, the piston cylinder is internally provided with two cavities, the upper cavity is matched with the lower cylindrical structure of the piston rod, and the lower cavity is in an elongated structure and is provided with a clamping groove for installing a pipette gun head at the bottom end.

[0014] Specifically, the outer diameter of the clamping groove is matched with the inner diameter of the pipette gun head.

[0015] Further, a support frame is additionally arranged between the motor and the fixed seat.

[0016] Further, a sensor is additionally installed at the top end position of the lead screw.

[0017] Specifically, the automatic pipetting device is controlled by PLC and is driven by a motor.

[0018] The beneficial effects of the utility model lie in that: 1. the automatic pipetting device for radionuclides and liquid medicine is program-controlled, can accurately calculate the material quantity, and improves the accuracy of the production process; 2. the pipetting device is used in combination with an automatic pipetting mechanism, manual operation is not needed throughout the whole process, and the whole pipetting process is carried out in a closed environment, aerosol leakage is avoided, and the radiation risk of technical personnel is reduced. BRIEF DESCRIPTION OF DRAWINGS

[0019] Fig. 1 It is a structural schematic view of the utility model;

[0020] Fig. 2 It is a structural schematic view of the piston rod of the utility model.

[0021] Among them, the reference signs are:

[0022] 1-lead screw; 2-motor; 3-piston rod; 4-limiting baffle; 5-guide shaft; 6-gun head assembly; 7-piston cylinder; 8-fixed seat; 9-support frame; 10-spring assembly; 11-guide shaft groove; 12-spring groove; 13-sealing ring; 14-pipette gun head. DETAILED DESCRIPTION

[0023] The structural features of the utility model will be further described below in combination with the drawings and examples, so that those skilled in the art can implement them according to the description. The preferred embodiments in the following description are only as examples, and other obvious modifications can be thought of by those skilled in the art.

[0024] AsFigs. 1-2 As shown in the drawings, the automatic liquid transfer device for radionuclide and liquid medicine comprises a transmission assembly, a fixing assembly and a gun head assembly 6 from top to bottom; the fixing assembly comprises a limiting baffle 4, a piston cylinder 7 and a fixing seat 8;

[0025] The fixing seat 8 is fixed to the outer side of the piston cylinder 7; the gun head assembly 6 is connected with the limiting baffle 4 through a guide shaft 5, the guide shaft 5 penetrates the fixing seat 8 from top to bottom; the gun head assembly 6 is sleeved on the outer side of the piston cylinder 7.

[0026] The transmission assembly comprises a lead screw 1, a motor 2 and a piston rod 3; the upper part of the lead screw 1 is arranged in the motor 2, the lower end of the lead screw 1 is fixed with the piston rod 3; the piston rod 3 penetrates the limiting baffle 4 and the lower part is located in the cavity of the piston cylinder 7.

[0027] The top end of the piston rod 3 is in the form of a platform and is located above the limiting baffle 4; the middle part of the piston rod 3 is provided with a groove and is clamped in the through hole in the center of the limiting baffle 4; the lower part of the piston rod 3 is in the form of a cylinder.

[0028] The fixing seat 8 is internally provided with a plurality of guide shaft grooves 11, the top opening of the guide shaft groove 11 is further provided with a spring groove 12, a spring assembly 10 is arranged in the spring groove 12, the top end of the spring assembly 10 is fixed to the bottom of the limiting baffle 4, and the bottom end of the spring assembly 10 is located at the bottom of the spring groove 12.

[0029] The piston cylinder 7 is internally provided with two cavities from top to bottom, the inner diameter of the upper cavity is matched with the cylindrical structure of the lower part of the piston rod, the lower cavity is in the form of an elongated structure and is provided with a clamping groove for mounting a liquid transfer device gun head 14 at the bottom end.

[0030] The motor 2 and the fixing seat 8 are further provided with a support frame 9.

[0031] The top end position of the lead screw 1 is further provided with a sensor.

[0032] The automatic liquid transfer device for radionuclide and liquid medicine is used in cooperation with an automatic liquid transfer mechanism, the liquid transfer device is fixed on the automatic liquid transfer mechanism, corresponding programs are set according to process requirements, and the automatic liquid transfer process can be realized by controlling program operation.

[0033] The working principle of the liquid transfer device is as follows:

[0034] The sensor detects the top end of the lead screw 1, the site is recorded as the starting position of the movement of the lead screw 1; the system sends a command, the lead screw 1 moves downward by a specified stroke under the action of the motor, at this time, the site reached by the top end of the lead screw 1 is recorded as a liquid transfer position; the lead screw 1 continues to move downward by a specified stroke, the top end reaches a site recorded as a gun head removal position. The starting position, the liquid transfer position and the gun head removal position of the lead screw 1 are respectively marked as position a, position b and position c.

[0035] (1) The pipette device is fixed on the automatic pipetting mechanism, and after the gun head is installed according to the instruction, the "liquid suction" instruction is executed. The motor 2 rotates clockwise, the lead screw 1 moves downward from position a to position b, and the air in the cavity is discharged. The motor 2 stops rotating.

[0036] (2) The gun head 14 of the pipette device is inserted below the liquid level, the motor 2 rotates counterclockwise, the lead screw 1 moves upward to position a, the motor 2 stops rotating, and the solution is sucked into the cavity of the piston cylinder 7.

[0037] (3) The pipette device moves to the specified liquid discharge position, and the "liquid discharge" instruction is executed. The motor 2 rotates clockwise, the lead screw 1 moves downward to position b, and the liquid is completely moved to the specified container. The motor 2 rotates counterclockwise, and the lead screw 1 moves upward to position a. The pipetting process is completed.

[0038] (4) The pipette device executes the "gun head removal" instruction. The pipette device moves to the specified gun head removal position, the motor 2 rotates clockwise, the lead screw 1 moves downward to position c, the upper part of the piston rod 3 moves downward to press the limiting baffle 4, the limiting baffle 4 drives the guide shaft 5 and the gun head assembly 6 to downwardly act, and the gun head 14 is ejected.

[0039] (5) Finally, the motor 2 rotates counterclockwise, the lead screw 1 moves upward to position a, and the gun head removal operation is completed.

[0040] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and deformations can be made to these embodiments without departing from the principles and spirits of the utility model, and the scope of the utility model is defined by the appended claims and their equivalents.

Claims

1. An automated pipetting device for radionuclides and pharmaceutical solutions, comprising, from top to bottom, a transmission assembly, a fixing assembly, and a pipette tip assembly; characterized in that, The fixing assembly includes a limiting baffle, a piston cylinder, and a fixing seat; The fixed base is fixed to the outside of the piston cylinder; the gun head assembly is connected to the limiting baffle through a guide shaft, which passes through the fixed base vertically; the gun head assembly is sleeved on the outside of the piston cylinder.

2. The automated pipetting device according to claim 1, characterized in that, The transmission assembly includes a lead screw, a motor, and a piston rod; the upper part of the lead screw is built into the motor, and the lower end of the lead screw is fixed to the piston rod; the piston rod passes through the limiting baffle, and its lower part is located in the cavity of the piston cylinder.

3. The automated pipetting device according to claim 2, characterized in that, The piston rod has a platform-shaped top end, located above the limiting baffle; the piston rod has a groove in the middle, which engages with the through hole in the center of the limiting baffle; the lower part of the piston rod is cylindrical.

4. The automated pipetting device according to claim 1, characterized in that, The fixed base has several guide shaft grooves inside, and a spring groove is opened at the top of the guide shaft groove. A spring assembly is installed in the spring groove. The top end of the spring assembly is fixed to the bottom of the limiting baffle, and the bottom end of the spring assembly is placed at the bottom of the spring groove.

5. The automated pipetting device according to claim 1, characterized in that, The piston cylinder has two cavities inside, an upper cavity and a lower cavity. The inner diameter of the upper cavity matches the cylindrical structure of the lower part of the piston rod, while the lower cavity has a slender structure and a slot at the bottom for installing a pipette tip.

6. The automated pipetting device according to claim 2, characterized in that, A support frame is also provided between the motor and the fixed base.

7. The automated pipetting device according to claim 2, characterized in that, A sensor is also installed at the top of the lead screw.

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