Portable manual cell purification and separation magnetic frame

Abstract

The utility model provides a portable manual cell purification and separation magnetic frame, which relates to the field of cell purification and separation magnetic frames and comprises a frame provided with a first fixing structure and a second fixing structure below the first fixing structure. The magnetic attraction part is restrained by a first fixing structure, and the test tube rack is restrained by a second fixing structure; the magnetic attraction part is provided with a plurality of channels, the test tube rack is provided with two rows of through holes, and at least one row of through holes and the plurality of channels of the magnetic attraction part are overlapped one by one in an overlooking view angle and are used for aligning the liquid outlet position of the magnetic separation column to the through holes overlapped with the channels after the channels restrain the magnetic separation column. The magnetic suction part is positioned and restrained to prevent the magnetic suction part from moving, the test tube rack system is arranged to position the test tubes, the operation time is effectively saved, and the problem of solution spilling caused by manual mistaken touch can be prevented.

Description

TECHNICAL FIELD

[0001] The utility model relates to cell purification separation magnetic force frame field especially, a portable manual cell purification separation magnetic force frame is provided. BACKGROUND

[0002] Cell purification separation magnetic force frame is constituted by metal support, magnetic separation column and multichannel magnet device, can collect separation cell solution component A and cell solution component B. Feedback, the multichannel magnet device carried by cell purification separation magnetic force frame does not have corresponding limiting structure to be positioned, and it is easy to skew during use, in addition, the collection area does not have the container fixing structure of special use, and the container needs to be aligned with the liquid outlet position of magnetic separation column one by one to carry out collection, in addition to this, the container is not fixed with the support, when the container is touched by mistake, the container is also easy to deviate from the liquid outlet position, and there are many limitations on the use level, for this, this paper proposes a portable manual cell purification separation magnetic force frame. SUMMARY

[0003] The utility model discloses a portable manual cell purification separation magnetic force frame, which is used to solve the above technical problems.

[0004] The utility model discloses a portable manual cell purification separation magnetic force frame, which is used to solve the above technical problems.

[0005] A portable manual cell purification separation magnetic force frame, comprising a frame, the frame has a first fixing structure, and a second fixing structure is arranged below the first fixing structure.

[0006] The utility model also comprises a magnetic attraction part constrained by the first fixing structure and a test tube rack constrained by the second fixing structure.

[0007] The magnetic attraction part has multiple channels, and the test tube rack has two rows of through holes, wherein at least one row of through holes coincides with the multiple channels of the magnetic attraction part from the top view, and the liquid outlet position of the magnetic separation column is aligned with the through hole coinciding with the channel after the channel constrains the magnetic separation column.

[0008] Preferably, the first fixing structure is a frame sleeve provided with a groove, and the magnetic attraction part enters the frame sleeve from the groove.

[0009] Preferably, the magnetic attraction part in the frame sleeve protrudes outward relative to the frame sleeve, and the outward protruding part is the setting area of the multiple channels.

[0010] Preferably, the second fixing structure is a limiting block arranged on the frame, and the number of limiting blocks corresponds to the number of corner of the bottom of the test tube rack.

[0011] Preferably, the multiple limiting blocks form a constraint area at the bottom of the test tube rack.

[0012] Preferably, the test tube rack has two layers, each layer having two rows of through holes.

[0013] The utility model discloses the beneficial effect is:

[0014] 1. The utility model discloses the positioning constraint of magnetic attraction part, prevent its appearance removal, still set up test tube rack system and position test tube, effective operation time is saved, still can prevent the solution spilling problem caused by artificial error touch later.

[0015] 2. The utility model discloses the magnetic attraction part is fixed by frame cover, after adopting this fixed mode, the frame can change into for example lightweight material such as plastics. DRAWINGS

[0016] Figure 1 It is a portable hand -made cell purification separation magnetic frame structure schematic view;

[0017] Figure 2 It is Figure 1 The structure schematic view of removing test tube rack and multichannel magnetic attraction part shown in the structure;

[0018] Figure 3 It is Figure 1 The side view of the structure shown in the structure;

[0019] Reference signs: 1, first board;2, second board;3, third board;4, frame cover;5, magnetic attraction part;6, channel;7, limit block;8, test tube rack;9, through hole. DETAILED DESCRIPTION

[0020] In order to facilitate understanding of the utility model, the utility model will be described more comprehensively below with reference to the relevant drawings. The preferred embodiments of the utility model are shown in the drawings. However, the utility model can be realized in many different forms, and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the understanding of the disclosure of the utility model more thorough and comprehensive.

[0021] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the utility model belongs. The terms used in the specification of the utility model herein are only for the purpose of describing specific embodiments and are not intended to limit the utility model.

[0022] The specific embodiments of the utility model will be described below with reference to the drawings.

[0023] Embodiment 1

[0024] In this embodiment, a portable hand -made cell purification separation magnetic frame is proposed, please refer to Figures 1-3The portable manual cell purification and separation magnetic frame comprises a frame, a first fixing structure arranged on the frame, and a second fixing structure below the first fixing structure.

[0025] In the embodiment, the frame comprises a first plate 1, a second plate 2 and a third plate 3, wherein the first plate 1 is at an angle with the second plate 2, and the third plate 3 is an extension structure of the second plate 2. Further, the first fixing structure is located outside the third plate 3, and the second fixing structure is located above the first plate 1. Further, the first fixing structure is a frame sleeve 4 provided with a slot, and the second fixing structure is four limiting blocks 7 arranged above the first plate 1.

[0026] In the embodiment, the magnetic attraction part 5 is arranged in the frame sleeve 4, wherein the magnetic attraction part 5 arranged in the frame sleeve 4 protrudes outward relative to the frame sleeve 4, and eight channels 6 are arranged on the outward protruding part. It should be noted that the channels 6 are used to constrain the magnetic separation column.

[0027] In the embodiment, the test tube rack 8 is positioned by the four limiting blocks 7. It should be noted that the test tube rack 8 has two rows of through holes 9, wherein the first row of through holes 9 is identified as region A in Figure 1 , and the second row of through holes 9 is identified as region B in Figure 1 . Further, the number of a row of through holes 9 is eight. Further, the first row of through holes 9 and the eight channels 6 at the magnetic attraction part 5 coincide under the top view angle. In this way, when the channels 6 constrain the magnetic separation column, the liquid outlet position of the magnetic separation column can be aligned with the through holes 9.

[0028] The working process of the portable manual cell purification and separation magnetic frame is as follows:

[0029] First, the magnetic attraction part 5 with eight channels 6 is positioned in the frame sleeve 4, and then eight magnetic separation columns are inserted into the channels 6 one by one for fixation;

[0030] Second, eight test tubes for collecting cell solution component A are placed in the first row of through holes 9 of the test tube rack 8, and the tube opening of the test tube is adjusted to the liquid outlet position of the magnetic separation column;

[0031] Third, the cell solution to be separated is added to the magnetic separation column, and the cell solution flows down naturally by gravity, and the cell solution component A flowing down is caught by the test tube located in region A, and then an appropriate amount of cleaning solution is added, and the test tube continues to catch the remaining cell solution component A;

[0032] Fourthly, the eight test tubes for collecting the cell solution component B are put into the second row of through holes 9 of the test tube rack 8, then the eight magnetic separation columns are separated from the channel 6 and inserted into the second row of through holes 9 one by one (the magnetic separation column extends into the test tube), next, an appropriate amount of elution solution is added, a plug is inserted into the magnetic separation column, and the cell solution component B is punched into the test tube based on pressure.

[0033] The technical features of the above-described embodiments can be combined in any manner. For the sake of brevity, not all possible combinations of the technical features in the above-described embodiments are described, however, as long as the combination of the technical features does not result in a contradiction, it should be considered within the scope of the present disclosure.

[0034] The above-described embodiments only express several implementation manners of the present application, the description is relatively specific and detailed, but it should not be understood as a limitation on the scope of the present application. It should be pointed out that, for those skilled in the art, without departing from the concept of the present application, a number of modifications and improvements can be made, which are all within the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the appended claims.

Claims

1. A convenient manual magnetic rack for cell purification and separation, characterized in that: It includes a frame, which has a first fixed structure and a second fixed structure below the first fixed structure; It also includes a magnetic suction part constrained by a first fixing structure and a test tube rack constrained by a second fixing structure; the magnetic suction part has multiple channels and the test tube rack has two rows of through holes, wherein at least one row of through holes coincides with multiple channels of the magnetic suction part in a top view, which is used to align the liquid outlet position of the magnetic separation column with the through hole that coincides with the channel after the channel constrains the magnetic separation column.

2. The convenient manual cell purification and separation magnetic rack according to claim 1, characterized in that: The first fixing structure is a frame sleeve with a groove, and the magnetic part enters the frame sleeve through the groove.

3. The convenient manual cell purification and separation magnetic rack according to claim 2, characterized in that: The magnetic part located inside the frame extends outward relative to the frame, and the outwardly extended part is the setting area of ​​the multiple channels.

4. The convenient manual cell purification and separation magnetic rack according to claim 1, characterized in that: The second fixing structure is a limiting block set on the frame, wherein the number of limiting blocks corresponds to the number of corners at the bottom of the test tube rack.

5. A convenient manual cell purification and separation magnetic rack according to claim 4, characterized in that: Multiple limiting blocks form a constraint area at the bottom of the test tube rack.

6. The convenient manual cell purification and separation magnetic rack according to claim 1, characterized in that: The test tube rack has two layers, and each layer has two rows of through holes.

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