Dissolution instrument
By designing a dissolution apparatus that includes a constant temperature chamber, dissolution cups, a drive device, and a slide plate, the problem of measurement deviation caused by differences in the order of tablet or capsule dispensing was solved. This invention enables simultaneous drug dispensing in multiple dissolution cups and automatic timed dispensing, thereby improving experimental accuracy and efficiency.
Patent Information
- Application Number
- CN202423137457.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-19
- Publication Date
- 2025-12-16
- Estimated Expiration
- 2034-12-19
AI Technical Summary
Existing dissolution apparatuses suffer from measurement deviations due to differences in the order of tablet or capsule dispensing, and are also inconvenient to operate.
A dissolution apparatus was designed, comprising a constant temperature chamber, a dissolution cup, a drive device, a cover plate, and a slide plate. The slide plate is driven by a cylinder to align the drug dispensing hole with the drug injection hole, enabling the simultaneous injection of multiple drugs. It is also equipped with a drug storage box for automatic timed injection.
It enables simultaneous drug dispensing from multiple dissolution vessels, reducing experimental errors, and improves operational efficiency and accuracy through an automated control system.
Smart Images
Figure CN223679160U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to medicine experiment equipment technical field more specifically, relate to a kind of dissolution tester. BACKGROUND
[0002] Drug dissolution tester is a kind of under certain conditions, determine the speed and the extent of dissolution from tablet or capsule etc. Solid preparation, drug dissolution degree directly influences drug in vivo absorption and utilization, is an internal index of evaluating drug quality, can effectively distinguish the difference of the same kind of drug bioavailability, so it is one of the necessary inspection items of drug quality control, dissolution tester needs to be dosed during testing process, needs to be dosed into dissolution cup in order by human tablet or capsule, this dosing mode makes tablet or capsule enter different several dissolution cups and produce sequence, lead to measurement result deviation, also bring great inconvenience to work, thus need a kind of technical scheme to solve the above problems. UTILITY MODEL CONTENT
[0003] The utility model aims at overcoming the deficiency of prior art, can simultaneously dose medicine into each dissolution cup, and provides a kind of dissolution tester.
[0004] In order to achieve the above object, the utility model adopts the following technical scheme:
[0005] The utility model discloses a kind of dissolution tester, including thermostat, dissolution cup, drive device, cover plate, sliding plate, the dissolution cup at least part is located in the thermostat, the drive device includes stirring rod, the lower end of the stirring rod is inserted into the dissolution cup, the cover plate is between the drive device and the dissolution cup, the sliding plate is slidably installed on the upper end surface of the cover plate, the cover plate is equipped with through-hole, the stirring rod passes through the through-hole, the cover plate is equipped with dosing hole, the sliding plate is equipped with medicine taking hole, the sliding plate sliding can be connected or staggered the dosing hole and the medicine taking hole.
[0006] Further, the sliding plate is equipped with first waist-shaped hole, the stirring rod passes through the first waist-shaped hole, the extension direction of the first waist-shaped hole is consistent with the sliding direction of the sliding plate.
[0007] Further, the upper end surface of the cover plate is equipped with strip-shaped groove, sliding rail is installed in the strip-shaped groove, the sliding rail is installed sliding block, the sliding block can slide along the sliding rail, the sliding block is fixedly connected with the sliding plate, the upper end surface of the sliding block is flush with the upper end surface of the cover plate.
[0008] Further, the cover plate is installed air cylinder, the air cylinder drives the sliding plate to slide, when the dosing hole and the medicine taking hole position stagger, the medicine taking hole is located on the side of the dosing hole close to the air cylinder.
[0009] Further, the medicine feeding hole comprises a slope, the slope is located at one side surface of the medicine feeding hole close to the air cylinder, and the upper end of the slope is inclined towards the direction close to the air cylinder.
[0010] Further, the medicine storage box is capable of storing medicines, the medicine taking hole is aligned with the medicine storage box when the medicine feeding hole and the medicine taking hole are staggered, and the medicine taking hole takes one medicine from the medicine storage box and feeds the medicine into the medicine feeding hole each time.
[0011] Further, the medicine storage box comprises a connecting column and a medicine storage tube, the connecting column is fixedly installed on the upper end surface of the cover plate, the sliding plate is provided with a second waist-shaped hole, the connecting column passes through the second waist-shaped hole, and the medicine storage tube is located above the medicine taking hole when the medicine feeding hole and the medicine taking hole are staggered.
[0012] The utility model discloses the beneficial effects are:
[0013] 1. The utility model discloses can place multiple medicines in each medicine taking hole, the air cylinder promotes the sliding plate to make the medicine taking hole and the medicine feeding hole align, and the medicines in each medicine taking hole can fall into corresponding multiple dissolution cups simultaneously, so that the medicines are put into multiple dissolution cups simultaneously, and the error of experiment is reduced.
[0014] 2. The utility model discloses including medicine storage box can temporarily store medicines, and the sliding plate takes one medicine from the medicine storage box and feeds the medicine into the medicine feeding hole each time when sliding through the medicine taking hole, so that the medicines in the medicine storage box are prepared to be placed, and the medicines are put into the medicine feeding hole automatically and regularly by controlling the control system. DRAWINGS
[0015] Figure 1 It is a schematic view of the embodiment.
[0016] Figure 2 It is a schematic view of the cover plate and the sliding plate in the embodiment.
[0017] Figure 3 It is a sectional view of the cover plate and the ring plate in the embodiment.
[0018] Figure 4 It is a schematic view of the cover plate in the embodiment.
[0019] Figure 5 It is a schematic view of the sliding plate in the embodiment.
[0020] Marked: 1, thermostat; 2, dissolution cup; 3, drive device; 31, stirring rod; 4, cover plate; 41, through hole; 42, dosing hole; 421, inclined surface; 43, strip groove; 431, sliding rail; 432, sliding block; 44, air cylinder; 5, sliding plate; 51, first waist-shaped hole; 52, medicine taking hole; 53, second waist-shaped hole; 6, medicine storage box; 61, connecting column; 62, medicine storage tube. DETAILED DESCRIPTION
[0021] The technical solutions in the embodiments will be described clearly and completely below in conjunction with the drawings in the embodiments. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the present application.
[0022] As shown in Figure 1 , the present embodiment discloses a dissolution instrument, comprising a thermostat 1, a dissolution cup 2, a drive device 3, a cover plate 4 and a sliding plate 5. The thermostat 1 is used for simulating the ambient temperature. The dissolution cup 2 is at least partially located in the thermostat 1. The drive device 3 comprises a stirring rod 31. The lower end of the stirring rod 31 extends into the dissolution cup 2. The stirring rod 31 rotates to agitate the dissolution medium in the dissolution cup 2, so that the medicine in the medium is dissolved.
[0023] As shown in Figure 4 , Figure 5 , the cover plate 4 is located between the drive device 3 and the dissolution cup 2. The cover plate 4 can be close to or away from the upper end opening of the dissolution cup 2 through the lifting device. When the cover plate 4 is at the lowest point, it can cover the upper end opening of the dissolution cup 2. The cover plate 4 is provided with a through hole 41, and the stirring rod 31 passes through the through hole 41. The sliding plate 5 is slidingly installed on the upper end surface of the cover plate 4. The upper end surface of the cover plate 4 is provided with a strip groove 43. The strip groove 43 is installed with a sliding rail 431. The sliding rail 431 is installed with a sliding block 432. The sliding block 432 can slide along the sliding rail 431. The sliding block 432 is fixedly connected with the sliding plate 5. The upper end surface of the sliding block 432 is flush with the upper end surface of the cover plate 4. The sliding plate 5 can slide along the sliding rail 431 on the upper end of the cover plate 4.
[0024] The sliding plate 5 is provided with a first waist-shaped hole 51. The stirring rod 31 passes through the first waist-shaped hole 51. The extension direction of the first waist-shaped hole 51 is consistent with the sliding direction of the sliding plate 5. The first waist-shaped hole 51 prevents the sliding plate 5 from interfering with the stirring rod 31 when sliding.
[0025] As shown in Figure 2 , Figure 3As shown, the cover plate 4 is provided with a medicine feeding hole 42, and the sliding plate 5 is provided with a medicine taking hole 52, and the sliding plate 5 is capable of connecting or staggering the medicine feeding hole 42 and the medicine taking hole 52 by sliding, the medicine taking hole 52 and the medicine feeding hole 42 are staggered when the cylinder 44 is retracted, the lower end surface of the sliding plate 5 closes the upper end surface of the medicine feeding hole 42, which can prevent dust and the like from entering the dissolution cup 2, and the upper end surface of the cover plate 4 forms a plane for preventing medicine in the medicine taking hole 52, at this time, the medicine can be placed in the medicine taking hole 52, when the cylinder 44 is extended, the medicine taking hole 52 and the medicine feeding hole 42 are connected, and the medicine in the medicine taking hole 52 is fed into the dissolution cup 2 through the medicine feeding hole 42, and the medicine in the plurality of medicine taking holes 52 can fall into the corresponding dissolution cup 2 at the same time, thereby reducing the error of experiments in each dissolution cup 2.
[0026] When the medicine feeding hole 42 and the medicine taking hole 52 are staggered, the medicine taking hole 52 is located on the side of the medicine feeding hole 42 close to the cylinder 44, the medicine feeding hole 42 comprises an inclined surface 421, the inclined surface 421 is a side surface of the medicine feeding hole 42 close to the cylinder 44, the upper end of the inclined surface 421 is inclined toward the direction close to the cylinder 44, the inclined surface 421 can expand the upper end surface of the medicine feeding hole 42, prevent the medicine from being stuck, and guide the medicine entering the medicine feeding hole 42 from one side of the inclined surface 421, so that the medicine can more smoothly slide into the medicine feeding hole 42.
[0027] As shown in the drawings, Figure 2 , Figure 3 The embodiment further comprises a medicine storage box 6, the medicine storage box 6 comprises a connecting column 61 and a medicine storage pipe 62, the connecting column 61 is fixedly installed on the upper end surface of the cover plate 4, the sliding plate 5 is provided with a second waist-shaped hole 53, the connecting column 61 passes through the second waist-shaped hole 53, and the sliding plate 5 is prevented from interfering with the connecting column 61 by sliding, the medicine storage box 6 can store medicine, the upper end opening of the medicine storage pipe 62 can put the medicine, the medicine can be temporarily stored in the medicine storage pipe 62, and the required medicine can be placed in sequence from top to bottom, when the medicine feeding hole 42 and the medicine taking hole 52 are staggered, the medicine taking hole 52 is aligned with the medicine storage pipe 62, the medicine storage pipe 62 is located above the medicine taking hole 52, and the lowest medicine in the medicine storage pipe 62 falls into the medicine taking hole 52, when the medicine taking hole 52 is away from below the medicine storage pipe 62, the upper end surface of the sliding plate 5 seals the lower end opening of the medicine storage pipe 62, and the sliding plate 5 takes one medicine from the medicine storage box 6 through the medicine taking hole 52 each time and feeds the medicine into the medicine feeding hole 42, and the control system controls the cylinder 44 to drive at a fixed time to automatically feed the medicine at a fixed time.
[0028] The preferred embodiments of the present application have been described above, the protection scope of the present application is not limited to the above-mentioned embodiments, any technical scheme falling within the idea of the present application belongs to the protection scope of the present application. It should be noted that, for ordinary skilled in the art, some improvements and decorations without departing from the principle of the present application can also be considered as the protection scope of the present application.
Claims
1. A dissolution apparatus characterized in that, The dissolution test device comprises a thermostat (1), a dissolution cup (2), a driving device (3), a cover plate (4), and a sliding plate (5), the dissolution cup (2) is at least partially located in the thermostat (1), the driving device (3) comprises a stirring rod (31), the lower end of the stirring rod (31) extends into the dissolution cup (2), the cover plate (4) is located between the driving device (3) and the dissolution cup (2), the sliding plate (5) is slidingly installed on the upper end surface of the cover plate (4), the cover plate (4) is provided with a through hole (41), the stirring rod (31) passes through the through hole (41), the cover plate (4) is provided with a medicine feeding hole (42), the sliding plate (5) is provided with a medicine taking hole (52), and the sliding plate (5) can slidingly communicate or stagger the medicine feeding hole (42) and the medicine taking hole (52).
2. The dissolution apparatus of claim 1, wherein, The sliding plate (5) is provided with a first waist-shaped hole (51), the stirring rod (31) passes through the first waist-shaped hole (51), and the extension direction of the first waist-shaped hole (51) is consistent with the sliding direction of the sliding plate (5).
3. The dissolution apparatus of claim 1, wherein, The upper end surface of the cover plate (4) is provided with a strip-shaped groove (43), a sliding rail (431) is installed in the strip-shaped groove (43), the sliding rail (431) is installed with a sliding block (432), the sliding block (432) can slide along the sliding rail (431), the sliding block (432) is fixedly connected with the sliding plate (5), and the upper end surface of the sliding block (432) is flush with the upper end surface of the cover plate (4).
4. The dissolution apparatus of claim 1, wherein, The cover plate (4) is installed with a gas cylinder (44), the gas cylinder (44) drives the sliding plate (5) to slide, when the medicine feeding hole (42) and the medicine taking hole (52) are staggered, the medicine taking hole (52) is located on the side of the medicine feeding hole (42) close to the gas cylinder (44).
5. The dissolution apparatus of claim 4 wherein, The medicine feeding hole (42) comprises an inclined surface (421), the inclined surface (421) is the side surface of the side of the medicine feeding hole (42) close to the gas cylinder (44), and the upper end of the inclined surface (421) is inclined towards the direction close to the gas cylinder (44).
6. The dissolution apparatus of claim 1, wherein, The device comprises a medicine storage box (6), the medicine storage box (6) can store medicines, when the medicine feeding hole (42) and the medicine taking hole (52) are staggered, the medicine taking hole (52) is aligned with the medicine storage box (6), and the medicine taking hole (52) takes one medicine from the medicine storage box (6) each time and feeds the medicine into the medicine feeding hole (42).
7. The dissolution apparatus of claim 6 wherein, The medicine storage box (6) comprises a connecting column (61) and a medicine storage pipe (62), the connecting column (61) is fixedly installed on the upper end surface of the cover plate (4), the sliding plate (5) is provided with a second waist-shaped hole (53), the connecting column (61) passes through the second waist-shaped hole (53), and when the medicine feeding hole (42) and the medicine taking hole (52) are staggered, the medicine storage pipe (62) is located above the medicine taking hole (52).