Nucleic acid extraction device for nucleic acid extractor

Abstract

The utility model discloses a nucleic acid extraction device for a nucleic acid extractor, which comprises an extraction device control main body, the upper end of the inner side of the extraction device control main body is movably connected with an extraction mixer, and the inner side of the extraction device control main body is movably connected with a magnetic bar sleeve frame. According to the nucleic acid extraction device for the nucleic acid extraction instrument, the deep hole plate positioning mechanism is arranged, so that the nucleic acid extraction device can be compatible with deep hole plates of various sizes, the universality and the flexibility of equipment are improved, the requirements of different experiments are met, clamping and positioning can be adjusted according to the deep hole plates of different sizes within a certain range, and the practicability is high. The whole device does not need to be replaced or adjusted, the device can adapt to deep hole plates of different sizes only by adjusting the deep hole plate positioning mechanism, time and labor cost are saved, the accurate positioning structure can ensure that the deep hole plate is kept stable in the nucleic acid extraction process, experimental errors caused by position deviation are reduced, and the accuracy of nucleic acid extraction is improved. And the reliability and repeatability of experimental results are improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of nucleic acid extraction device, specifically is a nucleic acid extraction device for nucleic acid extraction instrument. BACKGROUND

[0002] Nucleic acid extraction device is a kind of instrument specially used to extract nucleic acid (DNA or RNA) from various biological samples (such as blood, tissue, cell, etc.), these devices are usually based on magnetic bead method, centrifugal column method or other chemical and physical methods to realize the efficient extraction and purification of nucleic acid, and have wide application in medical diagnosis, gene research, environmental monitoring and other fields.

[0003] In the nucleic acid extraction process, deep well plate can be displaced due to mechanical operation or vibration, which can cause the position of deep well plate in the experimental process to be inaccurate, affect the reliability of experimental results, and the size of deep well plate is different, and the structure of the prior art cannot be adjusted according to the size of different deep well plates, cannot be compatible with deep well plates of multiple sizes, and brings certain adverse effects to the use process of people, therefore, we provide a nucleic acid extraction device for nucleic acid extraction instrument. UTILITY MODEL CONTENT

[0004] The technical problem solved is that, in view of the deficiencies of the prior art, the utility model provides a nucleic acid extraction device for nucleic acid extraction instrument, which has the advantages of adjusting positioning, improving operation precision, and being adjustable within a certain range according to deep well plates of different sizes, a deep well plate positioning mechanism is arranged, multiple sizes of deep well plates can be compatible, the versatility and flexibility of the equipment are improved, the needs of different experiments are met, the entire device does not need to be replaced or adjusted, only the deep well plate positioning mechanism needs to be adjusted to adapt to deep well plates of different sizes, time and labor cost are saved, the accurate positioning structure can ensure that deep well plate remains stable in the nucleic acid extraction process, reduces experimental errors caused by position deviation, improves the reliability and repeatability of experimental results, and can effectively solve the problems in the background art.

[0005] Technical scheme: in order to achieve the above object, the utility model takes the technical scheme that a nucleic acid extraction device for nucleic acid extraction instrument, including extraction device control main part, the upper end of the inner side of extraction device control main part is movably connected with extraction mixing device, the inner side of extraction device control main part is movably connected with magnetic bar sleeve frame, the inner side of magnetic bar sleeve frame is movably connected with magnetic bar sleeve, the lower end of the inner side of extraction device control main part is positioned and installed with deep well plate positioning mechanism, the inner side of deep well plate positioning mechanism is movably connected with deep well plate, the deep well plate positioning mechanism includes motor protection groove, adjusting connecting groove, control motor, through rotating rod, adjusting rod, center boundary plate, through connecting hole, L type clamping block, moving block and through threaded hole.

[0006] Preferably, the motor protection groove and the adjusting connecting groove are arranged on the two sides of the lower end of the inside of the extraction device control body, the adjusting connecting groove is located on one side of the motor protection groove, and the control motor is located on the inside of the motor protection groove.

[0007] Preferably, the through rotating rod is located at one end of the control motor and on the inner wall of the extraction device control body, the adjusting rod is located on the inside of the adjusting connecting groove, and the center partition plate is located in the middle of the inner wall of the adjusting connecting groove.

[0008] Preferably, the through connecting hole is arranged on the center partition plate, the moving block is located at the lower end of the L-shaped clamping block, and the through threaded hole is arranged on the moving block.

[0009] Preferably, the lower end of the control motor is fixedly connected to the inside of the motor protection groove, one end of the through rotating rod penetrates the inner wall of the extraction device control body and is connected to the control motor, and the other end of the through rotating rod penetrates the inner wall of the adjusting connecting groove and is fixedly connected to one end of the adjusting rod.

[0010] Preferably, the outer wall of the center partition plate is fixedly connected to the middle of the inner wall of the adjusting connecting groove, the center partition plate is sleeved on the outer wall of the adjusting rod through the through connecting hole, the lower end of the L-shaped clamping block is fixedly connected to the upper end of the moving block, and the moving block is sleeved on the two ends of the outer wall of the adjusting rod through the through threaded hole.

[0011] Beneficial effects: Compared with the prior art, the nucleic acid extraction device for a nucleic acid extractor has the following beneficial effects: the nucleic acid extraction device for a nucleic acid extractor has the following beneficial effects: the deep well plate positioning mechanism is provided, the moving block is sleeved on the two ends of the outer wall of the adjusting rod through the through threaded hole, the control motor in the motor protection groove drives the through rotating rod to drive the adjusting rod to rotate in the inside of the adjusting connecting groove, the moving block moves on the outer wall of the adjusting rod, the L-shaped clamping block on the upper end of the moving block can clamp and position the four corners of the deep well plate, a plurality of sizes of deep well plates can be compatible, the versatility and flexibility of the equipment are improved, the needs of different experiments are met, the deep well plate can be adjusted and clamped and positioned according to different sizes of deep well plates within a certain range, the entire device does not need to be replaced or adjusted, and only the deep well plate positioning mechanism needs to be adjusted to adapt to deep well plates of different sizes, time and labor cost are saved, the accurate positioning structure can ensure that the deep well plate remains stable during the nucleic acid extraction process, experimental errors caused by position deviation are reduced, and the reliability and repeatability of experimental results are improved. BRIEF DESCRIPTION OF DRAWINGS

[0012] Figure 1 It is a whole structure schematic view of the nucleic acid extraction device for a nucleic acid extractor.

[0013] Figure 2The utility model relates to a part structure schematic diagram of extraction device control main part and reagent box positioning mechanism in nucleic acid extraction device for nucleic acid extraction instrument.

[0014] Figure 3 The utility model relates to a part structure exploded schematic diagram of reagent box positioning mechanism in nucleic acid extraction device for nucleic acid extraction instrument.

[0015] Figure 4 The utility model relates to a part structure plan of reagent box positioning mechanism in nucleic acid extraction device for nucleic acid extraction instrument.

[0016] In the drawing: 1, extraction device control main part;2, extraction mixing ware;3, deep hole plate positioning mechanism;4, deep hole plate;5, magnetic bar sleeve frame;6, magnetic bar sleeve 301, motor protection groove;302, adjusting connecting groove;303, control motor;304, through rotating rod;305, adjusting rod;306, center boundary plate;307, through connecting hole;308, L type clamping block;309, moving block;310, through screw hole. Specific implementation

[0017] In order to make the technical means, creation features, purposes and effects of the utility model easy to understand, the utility model is further described below in combination with specific implementation.

[0018] As Figures 1-4 Shown, a nucleic acid extraction device for nucleic acid extraction instrument, including extraction device control main part 1, the upper end of the inside of extraction device control main part 1 is movably connected with extraction mixing ware 2, the inside of extraction device control main part 1 is movably connected with magnetic bar sleeve frame 5, the inside of magnetic bar sleeve frame 5 is movably connected with magnetic bar sleeve 6, the lower end of the inside of extraction device control main part 1 is positioned and installed with deep hole plate positioning mechanism 3, the inside of deep hole plate positioning mechanism 3 is movably connected with deep hole plate 4, and deep hole plate positioning mechanism 3 includes motor protection groove 301, adjusting connecting groove 302, control motor 303, through rotating rod 304, adjusting rod 305, center boundary plate 306, through connecting hole 307, L type clamping block 308, moving block 309 and through screw hole 310, through deep hole plate positioning mechanism 3, multiple sizes of deep hole plates can be compatible, the versatility and flexibility of the equipment are improved, the needs of different experiments are met, in a certain range, different sizes of deep hole plates can be adjusted and clamped and positioned, the entire device need not be replaced or adjusted, only the deep hole plate positioning mechanism can be adjusted to adapt to deep hole plates of different sizes, time and manpower cost are saved, and the accurate positioning structure can ensure that the deep hole plate remains stable during nucleic acid extraction, reduces experimental errors caused by position deviation, and improves the reliability and repeatability of experimental results.

[0019] Further, the motor protection groove 301 and the adjusting connecting groove 302 are both arranged on the two sides of the lower end of the inside of the extraction device control body 1, the adjusting connecting groove 302 is located on one side of the motor protection groove 301, the control motor 303 is located on the inside of the motor protection groove 301, and plays a role of adjusting control.

[0020] Further, the penetrating rotating rod 304 is located on one end of the control motor 303 and on the inner wall of the extraction device control body 1, the adjusting rod 305 is located on the inside of the adjusting connecting groove 302, the center partition plate 306 is located in the middle of the inner wall of the adjusting connecting groove 302, and plays a role of limiting and separating.

[0021] Further, the penetrating connecting hole 307 is arranged on the center partition plate 306, the moving block 309 is located on the lower end of the L-shaped clamping block 308, the penetrating threaded hole 310 is arranged on the moving block 309, and the penetrating threaded hole 310 and the adjusting rod 305 are matched with each other.

[0022] Further, the lower end of the control motor 303 is fixedly connected with the inside of the motor protection groove 301, one end of the penetrating rotating rod 304 penetrates the inner wall of the extraction device control body 1 and is connected with the control motor 303, the other end of the penetrating rotating rod 304 penetrates the inner wall of the adjusting connecting groove 302 and is fixedly connected with one end of the adjusting rod 305, and the control motor 303 drives the penetrating rotating rod 304 to drive the adjusting rod 305 to rotate together.

[0023] Further, the outer wall of the center partition plate 306 is fixedly connected with the middle of the inner wall of the adjusting connecting groove 302, the center partition plate 306 is sleeved on the outer wall of the adjusting rod 305 through the penetrating connecting hole 307, the lower end of the L-shaped clamping block 308 is fixedly connected with the upper end of the moving block 309, and the moving block 309 is sleeved on both ends of the outer wall of the adjusting rod 305 through the penetrating threaded hole 310, and when the adjusting rod 305 rotates, the moving block 309 can move oppositely on the outer wall thereof.

[0024] Working principle: a nucleic acid extraction device for a nucleic acid extractor, comprising an extraction device control body 1, an extraction mixing device 2, a reagent box positioning mechanism 3, a deep well plate 4, a magnetic rod sleeve frame 5 and a magnetic rod sleeve 6, in use, the deep well plate 4 can be placed at the lower end of the inside of the extraction device control body 1, and positioned by the reagent box positioning mechanism 3, the extraction device control body 1 can drive the extraction mixing device 2 to lift to the inside of the magnetic rod sleeve 6, the magnetic rod sleeve frame 5 can drive the magnetic rod sleeve 6 and the extraction mixing device 2 to move synchronously to the inside of the deep well plate 4 for extraction and mixing operation, through the reagent box positioning mechanism 3, the moving block 309 is sleeved on the outer wall of the adjusting rod 305 at both ends through the through screw hole 310, the control motor 303 in the motor protection groove 301 drives the through rotating rod 304 to drive the adjusting rod 305 to rotate in the inside of the adjusting connecting groove 302, so that the moving block 309 moves oppositely on the outer wall of the adjusting rod 305, and the L-shaped clamping block 308 on the upper end of the moving block 309 can clamp and position the four corners of the deep well plate 4, which can be compatible with deep well plates of various sizes, improve the versatility and flexibility of the equipment, meet the needs of different experiments, and can be adjusted and clamped and positioned according to deep well plates of different sizes within a certain range, without the need to replace or adjust the whole device, only the deep well plate positioning mechanism needs to be adjusted to adapt to deep well plates of different sizes, saving time and labor cost, and the accurate positioning structure can ensure that the deep well plate remains stable during nucleic acid extraction, reduces experimental errors caused by position deviation, and improves the reliability and repeatability of experimental results.

[0025] It should be noted that the relational terms herein such as first and second (one and two) and the like are used solely to distinguish one from another entity or action, without necessarily requiring or implying any such actual relationship or order between such entities or actions. Moreover, the terms "comprises", "comprising", or any other variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but can include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by an "including a" does not exclude the existence of additional identical elements in the process, method, article, or apparatus that includes the element.

[0026] The basic principle and main features of the present application and the advantages of the present application are shown and described above. Those skilled in the art should understand that the present application is not limited by the above examples, and the above examples and descriptions in the specification are only to illustrate the principles of the present application. Without departing from the spirit and scope of the present application, various changes and improvements can be made to the present application, and these changes and improvements all fall within the scope of the claimed present application. The scope of protection of the present application is defined by the appended claims and their equivalents.

Claims

1. A nucleic acid extraction apparatus for a nucleic acid extractor comprising an extraction apparatus control main body (1), characterized by: The upper end of the inside of the extraction device control body (1) is movably connected with an extraction mixing device (2), the inside of the extraction device control body (1) is movably connected with a magnetic rod sleeve frame (5), the inside of the magnetic rod sleeve frame (5) is movably connected with a magnetic rod sleeve (6), the lower end of the inside of the extraction device control body (1) is positioned and installed with a deep hole plate positioning mechanism (3), the inside of the deep hole plate positioning mechanism (3) is movably connected with a deep hole plate (4), the deep hole plate positioning mechanism (3) comprises a motor protection groove (301), an adjusting connecting groove (302), a control motor (303), a penetrating rotating rod (304), an adjusting rod (305), a center partition plate (306), a penetrating connecting hole (307), an L-shaped clamping block (308), a moving block (309) and a penetrating threaded hole (310).

2. The nucleic acid extraction apparatus for a nucleic acid extractor according to claim 1, characterized by: The motor protection groove (301) and the adjusting connecting groove (302) are both formed on the two sides of the lower end of the inside of the extraction device control body (1), the adjusting connecting groove (302) is located on one side of the motor protection groove (301), and the control motor (303) is located on the inside of the motor protection groove (301).

3. The nucleic acid extraction apparatus for a nucleic acid extractor according to claim 2, characterized by: The penetrating rotating rod (304) is located at one end of the control motor (303) and on the inner wall of the extraction device control body (1), the adjusting rod (305) is located on the inside of the adjusting connecting groove (302), and the center partition plate (306) is located at the middle of the inner wall of the adjusting connecting groove (302).

4. The nucleic acid extraction apparatus for a nucleic acid extractor according to claim 3, characterized by: The penetrating connecting hole (307) is formed on the center partition plate (306), the moving block (309) is located at the lower end of the L-shaped clamping block (308), and the penetrating threaded hole (310) is formed on the moving block (309).

5. The nucleic acid extraction apparatus for a nucleic acid extractor according to claim 4, characterized by: The lower end of the control motor (303) is fixedly connected with the inside of the motor protection groove (301), one end of the penetrating rotating rod (304) penetrates the inner wall of the extraction device control body (1) and is connected with the control motor (303), and the other end of the penetrating rotating rod (304) penetrates the inner wall of the adjusting connecting groove (302) and is fixedly connected with one end of the adjusting rod (305).

6. The nucleic acid extraction apparatus for a nucleic acid extractor according to claim 5, characterized by: The outer wall of the center partition plate (306) is fixedly connected with the middle of the inner wall of the adjusting connecting groove (302), the center partition plate (306) is sleeved on the outer wall of the adjusting rod (305) through the penetrating connecting hole (307), the lower end of the L-shaped clamping block (308) is fixedly connected with the upper end of the moving block (309), and the moving block (309) is sleeved on the two ends of the outer wall of the adjusting rod (305) through the penetrating threaded hole (310).

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