Biological sample transfer culture device
By utilizing a biosample transfer and culture device between the operating room and the embryology laboratory, and employing a transmission disc and positioning block design, errors in the biosample transfer process have been resolved. This has enabled stable and accurate transfer of culture dishes of different sizes, improving compatibility and safety.
Patent Information
- Application Number
- CN202422727197.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-08
- Publication Date
- 2025-12-23
- Estimated Expiration
- 2034-11-08
AI Technical Summary
In assisted reproductive technology, errors in the transfer of biological samples between the operating room and the embryology laboratory can occur due to the operation of personnel from different departments, and the poor compatibility of culture dishes of different sizes can also affect the accuracy of the transfer.
A biological sample transfer and culture device is designed, which uses a storage box installed on the cabinet and a rotating transmission plate inside. The installation slots correspond one-to-one with the pick-up and put-out ports. The transmission plate is rotated by the host computer to realize the accurate placement and removal of biological sample culture dishes. Through the cooperation of elastic elements and positioning blocks, it can adapt to culture dishes of different sizes to ensure stable clamping and transfer.
It improves the accuracy and adaptability of biological sample transfer, avoids handover errors caused by human factors, ensures stable transfer of culture dishes of different sizes, and can hold multiple culture dishes at the same time but remove one at a time, thus ensuring the stability and safety of the transfer process.
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Figure CN223705604U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to biological sample experiment equipment technical field especially, relates to a biological sample transfer culture device. BACKGROUND
[0002] In the surgical process of assisted reproductive medical treatment, the ovum of the patient is often obtained in the operating room, and the obtained ovum is delivered to the embryo laboratory for fertilization and culture. After the culture and fertilization are completed in the embryo laboratory, the patient's embryo is delivered to the operating room for embryo transplantation for pregnancy.
[0003] In the related art, a window for embryo delivery is usually arranged between the operating room and the embryo laboratory. After the ovum is obtained, the operating room personnel places the culture dish with a label at the window, and the embryo laboratory personnel obtains the culture dish and performs the subsequent process of embryo development and artificial insemination according to the label information.
[0004] In the related art, the biological sample transfer method is adopted, and the ovum culture dish needs to be manually taken and information confirmed by the embryo laboratory personnel during the delivery process. Since the personnel in the operating room and the embryo laboratory belong to different departments and teams, there is often a time difference between the storage and taking process of the embryo, and according to the different biological samples, the specifications of the culture dishes used for storage are also different. During the taking process of the embryo laboratory personnel, there is a transfer error caused by human factors, resulting in a medical accident. UTILITY MODEL CONTENT
[0005] In order to make up for the above shortcomings, the utility model provides a biological sample transfer culture device, which can solve the handover error problem of biological samples in the handover process caused by human factors in the related art, and can adapt to different specifications of the container of the biological sample container, improve the adaptability and transfer accuracy.
[0006] In order to achieve the above purpose, the utility model adopts the following technical scheme:
[0007] The utility model embodiment provides a biological sample transfer culture device, including the cabinet, the storage box is arranged on the cabinet, both ends of the storage box are located at opposite sides of the cabinet and the top is provided with the taking and placing opening respectively, the transmission disc is rotationally arranged in the storage box, a plurality of installation grooves matched with the taking and placing opening are arranged on the top of the transmission disc and spaced apart in the circumferential direction, two positioning blocks are oppositely arranged in the installation groove, the opposite sides of the two positioning blocks are connected with the side wall of the installation groove through the elastic piece, and the transmission disc is configured to rotate in the storage box to move the installation groove between the two taking and placing openings.
[0008] Optionally, the positioning block is arc-shaped, and the concave surfaces of the two positioning blocks are oppositely arranged.
[0009] Optionally, a plurality of positioning protrusions are uniformly arranged on the circular-arc concave surface of the positioning block.
[0010] Optionally, the positioning block and the positioning protrusions are rubber structural members.
[0011] Optionally, a circular-arc chamfered surface is arranged on the top of the positioning block.
[0012] Optionally, a sliding hole is radially arranged on the side wall of the mounting slot, a sliding column is protrusively arranged on the circular-arc convex surface of the positioning block, one end of the sliding column is slidably inserted into the sliding hole, the elastic member is an extrusion spring, and two ends of the extrusion spring are respectively connected with the bottom end of the sliding hole and the end of the sliding column.
[0013] Optionally, a sealing cover is rotatably arranged at the taking and placing opening, an extension column is arranged at one end of the sealing cover away from the rotating connection, a clamping block is arranged at the end of the extension column, and a limiting hole matched with the clamping block is arranged at one end of the taking and placing opening close to the edge of the storage box.
[0014] Optionally, a torque spring is fixedly connected at both sides of the top of the sealing cover, and the other end of the torque spring is fixedly connected on the side wall of the cabinet.
[0015] Optionally, a temperature control device and a gas supply device are further included, a heating plate is arranged at the bottom of the mounting slot, the heating plate is electrically connected with the temperature control device, and a gas supply channel is further arranged on the side wall of the mounting slot, and the gas supply channel is communicated with the gas supply device.
[0016] Optionally, a control panel is fixedly connected on the side wall of the cabinet, and the transmission disc, the temperature control device and the gas supply device are electrically connected with the control panel.
[0017] Compared with the prior art, the embodiments of the utility model have at least the following advantages:
[0018] The biological sample transfer culture device provided by the embodiment of the utility model, through the storage box which is arranged on the cabinet between two isolation spaces, the end of the storage box on both sides of the cabinet is respectively provided with a taking and placing opening to correspond to different positions of the biological sample which needs to be transferred. The transmission disc inside the storage box is rotatable, the mounting groove on the transmission disc is in one-to-one correspondence with the taking and placing opening, the biological sample culture dish is accurately placed, and the upper computer is used for controlling the accurate rotation to the taking and placing opening on the other side, so that the staff on the other side can accurately obtain the biological sample culture dish which needs to be transferred. Through the special structure design of the mounting groove, the adjustable interval is arranged oppositely, and the positioning block connected with the side wall of the mounting groove through the elastic element, different specifications of the culture dish can be stably clamped in the mounting groove, the adaptability and transfer stability are guaranteed, and the culture dish is prevented from being damaged. The plurality of mounting grooves arranged in the circumferential direction of the disc-shaped transmission disc can realize the simultaneous loading of the plurality of culture dishes, but only one culture dish can be taken out at a time and transported to the taking and placing opening on the other side after being positioned and recognized by the upper computer. The delivery error problem of the biological sample caused by human factors in the related art can be effectively solved, the container of the biological sample container of different specifications can be adapted, and the adaptability and transfer accuracy are improved. BRIEF DESCRIPTION OF DRAWINGS
[0019] Figure 1 A three-dimensional schematic view of a biological sample transfer culture device is provided in the utility model.
[0020] Figure 2 A structure schematic view of a storage box is provided in the utility model.
[0021] Figure 3 A structure schematic view of a transmission disc is provided in the utility model.
[0022] Figure 4 A top view structure schematic view of a storage box is provided in the utility model.
[0023] Figure 5 An internal control structure block diagram of a biological sample transfer culture device is provided in the utility model.
[0024] LEGEND:
[0025] 1, cabinet; 2, control panel; 3, storage box; 4, transmission disc; 5, mounting groove; 6, sliding column; 7, positioning block; 8, positioning protrusion; 11, elastic element; 12, sealing cover; 13, extension column; 14, clamping block; 16, torque spring; 31, taking and placing opening; 32, temperature control device; 33, gas supply device; 34, heating plate, 35, gas supply path; 51, sliding counterbore; 71, circular arc chamfer surface. DETAILED DESCRIPTION
[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0027] Figure 1 A three-dimensional schematic diagram of a biological sample transfer and culture device provided by this utility model; Figure 2 A schematic diagram of the structure of the storage box provided by this utility model; Figure 3 A schematic diagram of the structure of the transmission disc provided by this utility model; Figure 4 A top view of the storage box provided by this utility model; Figure 5 This is a block diagram of the internal control structure of the biological sample transfer and culture device provided by this utility model. Figures 1 to 5 As shown, this utility model embodiment provides a biological sample transfer and culture device, including a cabinet 1, a storage box 3 passing through the cabinet 1, the two ends of the storage box being located on opposite sides of the cabinet 1 and each having a pick-up and put-out port 31 on its top, a transmission disk 4 being rotatably arranged inside the storage box, the top of the transmission disk 4 having a plurality of mounting grooves 5 spaced apart along the circumference to match the pick-up and put-out ports 31, two positioning blocks 7 being arranged opposite each other in the mounting grooves 5, the opposite sides of the two positioning blocks 7 being connected to the side wall of the mounting grooves 5 through elastic members 11, the transmission disk 4 being configured to rotate within the storage box 3 so that the mounting grooves 5 move between the two pick-up and put-out ports 31.
[0028] In the embodiment of the utility model, the cabinet 1 of the biological sample transfer culture device can be installed in two different rooms isolated from each other, for example, between two laboratories needing to transfer biological sample culture dishes, and then the two ends of the storage box 3 are arranged in the two rooms respectively and correspond to the two rooms through the two taking and placing openings 31, thereby replacing the traditional window design. In use, the staff in one side room puts the culture dish to be transferred into the corresponding mounting groove 5 on the transmission disc 4 through the taking and placing opening 31 on one side. During this placing process, the information reading mechanism integrated on the cabinet 1 or the storage box 3 can scan and obtain the label information of the culture dish and upload it to the host computer for identification and recording. The host computer can locate the position of the culture dish to be transferred based on the data in the label information, including but not limited to using a preset computer program or manually operating the host computer. The control mechanism on the host computer or the cabinet 1 is used for distribution control to drive the transmission disc 4 to rotate so that the mounting groove 5 loaded with the culture dish rotates to the taking and placing opening 31 on the other side, and the staff in the other room can accurately take out the biological sample culture dish to be transferred from the taking and placing opening 31 on the other side. After the biological sample in the culture dish is subjected to a surgical test, the same process can be used for reverse operation to transfer the culture dish back to the initial room through the storage box 3 for further test operation.
[0029] The biological sample transfer culture device provided by the embodiment of the utility model is used for setting the storage box 3 on the cabinet 1 between two isolated spaces, and the taking and placing openings 31 are arranged on the ends of the storage box 3 on both sides of the cabinet 1 to correspond to different positions where the biological sample needs to be transferred. The rotatable transmission disc 4 is arranged in the storage box 3, the mounting grooves 5 are arranged on the transmission disc 4 in a circumferential direction and correspond to the taking and placing openings 31 one by one, the biological sample culture dish is accurately placed, and the transmission disc 4 is accurately rotated to the taking and placing opening 31 on the other side through the control of the host computer, so that the staff on the other side can accurately obtain the biological sample culture dish to be transferred. Through the special structure design of the mounting groove 5, the opposite mounting grooves 5 can be adjusted in distance, and the positioning block 7 connected to the side wall of the mounting groove 5 through the elastic member can stably clamp the culture dishes of different specifications in the mounting groove 5, so as to ensure the adaptability and transfer stability and avoid damage to the culture dishes. The plurality of mounting grooves 5 arranged in a circumferential direction on the disc-shaped transmission disc 4 can simultaneously accommodate a plurality of culture dishes, but only one culture dish can be taken out at a time after being identified and positioned by the host computer and transported to the taking and placing opening 31 on the other side. The problem of transfer error caused by human factors in the transfer process of biological samples in the related art can be effectively solved, different specifications of biological sample containers can be adapted, and the adaptability and transfer accuracy can be improved.
[0030] Optionally, the positioning blocks 7 are arc-shaped, and the arc concave surfaces of the two positioning blocks 7 are oppositely arranged. Illustratively, in the embodiment of the present application, for the most circular culture dish form, in the mounting groove 5 provided by the embodiment of the present application, the positioning blocks 7 used for providing clamping function from both sides are arranged as arc-shaped rubber structural members. When the culture dish is placed into the mounting groove 5, the two positioning blocks 7 are first pried apart, and at the same time, the elastic member 11 located between the positioning block 7 and the side wall of the mounting groove 5 is extruded and shrunk. When the culture dish is placed between the two positioning blocks 7, the two positioning blocks 7 will fasten and clamp the culture dish therebetween under the elastic force of the elastic member 11. At the same time of clamping, the positioning blocks contact the arc side of the culture dish which is also circular through the arc concave surfaces, which can effectively improve the contact area and ensure the clamping stability. The elastic positioning blocks 7 supported by the rubber structural members can adaptively deform based on the arc side of the culture dish of different specifications, so that the arc concave surfaces can be fully matched with the culture surface, and the clamping stability is further improved.
[0031] Optionally, a plurality of positioning protrusions 8 are uniformly and spacedly arranged on the arc concave surface of the positioning block 7. Illustratively, in the embodiment of the present application, the arc-shaped positioning protrusions 8 are arranged on the arc concave surface of the positioning block 7 for contacting the culture dish, which can improve the friction coefficient between the positioning block 7 and the culture dish, and further improve the clamping stability.
[0032] Optionally, a circular arc chamfer surface 71 is arranged on the top of the positioning block 7. Illustratively, in the embodiment of the present application, the circular arc chamfer surface 71 is arranged on the top of the positioning block 7. When the culture dish is placed between the two positioning blocks 7, the circular arc chamfer surface 71 can be used for limiting and guiding, so that the two positioning blocks 7 can be smoothly pried apart and lowered into the two positioning blocks 7, the assembly smoothness is improved, and scratching damage is avoided.
[0033] Optionally, a sliding counterbore 51 is radially arranged on the side wall of the mounting groove 5, a sliding column 6 is protrusively arranged on the arc convex surface of the positioning block 7, one end of the sliding column 6 is slidably inserted into the sliding counterbore 51, the elastic member 11 is an extrusion spring, and the two ends of the elastic member 11 are respectively connected with the bottom end of the sliding counterbore 51 and the end of the sliding column 6.
[0034] Optionally, the sealing cover 12 is rotatably arranged at the taking and placing opening 31, and the end of the sealing cover 12 away from the rotating connection is provided with an extension column 13, and the end of the extension column 13 is provided with a clamping block 14; the end of the taking and placing opening 31 close to the edge of the storage box 3 is provided with a limiting hole 15 matched with the clamping block 14. In the embodiment of the utility model, during the transfer of the biological sample, after the culture dishes are placed in the plurality of installation grooves 5 on the transmission disc 4, the sealing cover 12 at the taking and placing opening 31 can be pressed and closed during the process that the staff on the other side has not carried out the taking operation, so as to realize the closure of the taking and placing opening 31. At this time, the internal space of the storage box 3 is sealed as a whole, the heating plate 34 can be controlled to work through the temperature control device 32 integrated in the cabinet 1, so as to realize the constant temperature control of the culture dishes sealed and stored in the installation groove 5, and ensure the activity of the biological sample in the culture dishes during the transfer and static storage in the storage box 3. Meanwhile, the gas supply device 33 can be used to introduce the gas with specified components and concentration into the installation groove 5 through the gas supply gas path 35, so as to maintain the constant gas concentration level required by the biological sample for culture and development, and further ensure the activity of the biological sample during the transfer and storage and taking and placing. When the closing operation is carried out, the end clamping block 14 of the extension column 13 on the sealing cover 12 is clamped into the corresponding limiting hole 15, the clamping connection of the buckle structure is realized, the closing stability and sealing property are ensured, the sealing cover 12 can be made of high-temperature-resistant silica gel material, and the internal environment gas leakage is effectively prevented.
[0035] Optionally, the top of the sealing cover 12 is fixedly connected with a torque spring 16 on both sides, and the other end of the torque spring 16 is fixedly connected to the side wall of the cabinet 1. In the embodiment of the utility model, the torque spring 16 can provide sufficient elastic force for the sealing cover 12, so that the sealing cover 12 can be in the vertical opening position in the opening and non-operation state, the sample storage of the operator is facilitated, and the practicability is effectively improved.
[0036] Optionally, the side wall of the cabinet 1 is fixedly connected with a control panel 2, and the transmission disc 4, the temperature control device 32 and the gas supply device 33 are electrically connected with the control panel 2. In the embodiment of the utility model, the biological sample transfer and culture device can be provided with the control panel 2 on the side wall of the cabinet 1, which can observe and control the state in the storage box 3, for example, a touch control panel integrating display and operation. The start and stop of the transmission disc 4 can be controlled through the control panel 2, and the working state of the temperature control device 32 and the gas supply device 33, and the content contained in the label information of the biological sample to be transferred can be observed and confirmed, so that the transfer accuracy of the biological sample transfer and culture device is further improved.
[0037] Finally, it should be noted that: the above only for the preferred embodiments of the present application, and is not intended to limit the present application, although the foregoing embodiments of the present application has been described in detail, for the skilled in the art, it still can be modified, or for part of the technical features of the equivalent replacement, the spirit and principles of the present application, made any modification, equivalent replacement, improvement, etc., should be included within the scope of the present application.
Claims
1. A biological sample transfer culture device, characterized by, The utility model provides a kind of storage box, including cabinet (1), the storage box of being provided with on the cabinet (1) is placed, the two ends of the storage box are located at the opposite sides of the cabinet (1) and top are provided with respectively and take out and put in mouth (31), transmission disc (4) is rotatably arranged inside the storage box, the top of transmission disc (4) is provided with multiple installation slot (5) with the matching of the take out and put in mouth (31) along the circumference interval, two positioning blocks (7) are oppositely provided in the installation slot (5), the opposite side of the two positioning blocks (7) is connected with the side wall of the installation slot (5) by elastic element (11), and the transmission disc (4) is configured to rotate in the storage box (3), so that the installation slot (5) moves between the two take out and put in mouth (31).
2. The biological sample transfer culture device according to claim 1, wherein The positioning block (7) is arc-shaped, and the concave surfaces of the circular arcs of the two positioning blocks (7) are oppositely arranged.
3. The biological sample transfer culture device according to claim 2, wherein The concave surfaces of the circular arcs of the positioning blocks (7) are uniformly spaced to be provided with multiple positioning protrusions (8).
4. The biological sample transfer culture device according to claim 3, wherein The positioning block (7) and the positioning protrusion (8) are rubber structural members.
5. The biological sample transfer culture device according to claim 2, wherein The top of the positioning block (7) is provided with a circular arc chamfered surface (71).
6. The biological sample transfer culture device according to claim 2, wherein The side wall of the installation slot (5) is provided with a sliding counterbore (51) in the radial direction, and the convex surface of the positioning block (7) is provided with a sliding column (6) protruding therefrom. One end of the sliding column (6) is slidably inserted into the sliding counterbore (51), and the elastic element (11) is a compression spring. The two ends of the elastic element (11) are connected to the bottom end of the sliding counterbore (51) and the distal end of the sliding column (6), respectively.
7. The biological sample transfer culture device according to any one of claims 1 to 6, wherein It also includes a sealing cover (12) rotatably arranged at the take out and put in mouth (31). One end of the sealing cover (12) away from the rotating connection is provided with an extension column (13), and the distal end of the extension column (13) is provided with a clamping block (14). One end of the take out and put in mouth (31) close to the edge of the storage box (3) is provided with a limiting hole (15) matched with the clamping block (14).
8. The biological sample transfer culture device according to claim 7, wherein The top of the sealing cover (12) is fixedly connected with a torque spring (16) on both sides. The other end of the torque spring (16) is fixedly connected to the side wall of the cabinet (1).
9. The biological sample transfer culture device according to any one of claims 1 to 6, wherein It also includes a temperature control device (32) and a gas supply device (33). The bottom of the installation slot (5) is provided with a heating plate (34), and the heating plate (34) is electrically connected to the temperature control device (32). The side wall of the installation slot (5) is also provided with a gas supply channel (35), and the gas supply channel (35) is in communication with the gas supply device (33).
10. The biological sample transfer culture device according to claim 9, wherein The side wall of the cabinet (1) is fixedly connected with a control panel (2), and the transmission disc (4), the temperature control device (32) and the gas supply device (33) are electrically connected to the control panel (2).