Device applied to continuous flow photochemical reaction

Abstract

The utility model discloses a continuous flow photochemical reaction device which comprises a feeding tank, a photochemical reactor, a receiving tank and a first lifting device, the feeding tank is provided with a first feeding port, a first air pressure balance port and a first discharging port, and the photochemical reactor is provided with a reaction liquid inlet and a reaction liquid outlet which are both lower than the first discharging port. The reaction liquid inlet is connected with the first discharging port, the receiving tank is provided with a second feeding port, a second air pressure balancing port and a second discharging port, the second feeding port is connected with the reaction liquid outlet, the second discharging port is connected with the first feeding port, the second air pressure balancing port is connected with the first air pressure balancing port, and the first lifting device is connected with the bottom end of the receiving tank. The device is used for periodically enabling the receiving tank to move between the first height and the second height, and the technical problems that in the prior art, due to the fact that circulation is achieved through a peristaltic pump, reaction liquid corrodes all parts of the peristaltic pump, the equipment cost is high, adverse effects are caused to photochemical reactions, and even the photochemical reactions are forced to be interrupted are solved.

Description

TECHNICAL FIELD

[0001] The utility model belongs to optical synthetic technique field, especially relate to a kind of applied to continuous flow photochemical reaction device. BACKGROUND

[0002] Continuous flow reaction technology is used more and more widely in pharmaceutical and fine chemical production process, especially continuous flow photochemical reaction technology.In many continuous flow photochemical reactions, reaction liquid often needs to flow through reactor multiple times to obtain the expected raw material conversion rate, such as synthesis of various vitamin D drugs and synthesis of progesterone raw material drug, and the most critical photochemical reaction in its process often needs to flow through photochemical reactor multiple times to obtain satisfactory conversion rate.For this kind of reaction, currently, peristaltic pump is mainly used to realize continuous circulation of reaction liquid.

[0003] However, in continuous flow photochemical reaction, peristaltic pump is used to realize continuous circulation of reaction liquid, which not only increases equipment cost, but also causes corrosion of reaction liquid to each component of peristaltic pump, resulting in failure or even damage of peristaltic pump, and further causing adverse effects on reaction or forcing reaction to be interrupted. UTILITY MODEL CONTENT

[0004] The utility model aims at providing a kind of applied to continuous flow photochemical reaction device, to overcome the technical problem that, in continuous flow photochemical reaction, peristaltic pump is used to realize continuous circulation of reaction liquid, which not only increases equipment cost, but also causes corrosion of reaction liquid to each component of peristaltic pump, resulting in failure or even damage of peristaltic pump, and further causing adverse effects on reaction or forcing reaction to be interrupted.The specific technical scheme is as follows:

[0005] A kind of applied to continuous flow photochemical reaction device, including feed tank, photochemical reactor, receiving tank, first lifting device and control device;

[0006] The top of the feed tank is provided with a first feed inlet and a first gas pressure balance port, and the bottom is provided with a first discharge port;

[0007] The photochemical reactor is provided with a reaction liquid inlet and a reaction liquid outlet, the height of the reaction liquid inlet and the reaction liquid outlet is lower than the height of the first discharge port, and the reaction liquid inlet is connected with the first discharge port by a liquid inlet pipe;

[0008] The top of the receiving tank is provided with a second feed inlet and a second gas pressure balance port, and the bottom is provided with a second discharge port, the second feed inlet is connected with the reaction liquid outlet by a liquid outlet pipe, the second discharge port is connected with the first feed inlet by a material transfer pipe, and the second gas pressure balance port is connected with the first gas pressure balance port by a gas pressure balance pipe;

[0009] The first lifting device is connected with the bottom end of the receiving tank and is electrically connected with the control device, and the first lifting device is used for periodically moving the receiving tank between a first height and a second height, when the receiving tank is located at the first height, the height of the second feeding port is lower than the height of the reaction outflow port, and when the receiving tank is located at the second height, the height of the second discharging port is higher than the height of the first feeding port.

[0010] Preferably, the liquid inlet pipe, the liquid outlet pipe, the material transfer pipe and the air pressure balance pipe are soft corrosion-resistant pipes.

[0011] Preferably, the feeding tank and the receiving tank are both provided with liquid level meters, and the liquid level meters are electrically connected with the control device.

[0012] Preferably, the height of the reaction liquid inlet port is lower than the height of the reaction liquid outlet port.

[0013] Preferably, the bottom of the feeding tank is provided with a second lifting device, and the second lifting device is electrically connected with the control device and is used for changing the height of the feeding tank.

[0014] Preferably, the first lifting device and the second lifting device are both scissor-type hydraulic lifting devices.

[0015] Preferably, the reaction liquid inlet port is provided with a flow meter, and the flow meter is electrically connected with the control device.

[0016] Preferably, the bottom end of the feeding tank and the receiving tank are both provided with a circular table structure, and the first discharging port and the second discharging port are both arranged at one end with a small area of the circular table structure.

[0017] Preferably, the reaction liquid inlet port is provided with a liquid inlet valve, and the reaction liquid outlet port is provided with a liquid outlet valve, and the liquid inlet valve and the liquid outlet valve are both electrically connected with the control device.

[0018] Compared with the prior art, the present application has the following beneficial effects:

[0019] According to the technical scheme, the continuous flow photochemical reaction device is provided, the height of the reaction liquid inlet and the height of the reaction liquid outlet are lower than the height of the first liquid outlet, the feeding tank and the receiving tank are connected by the air pressure balance pipe, the height of the receiving tank is changed periodically between the first height and the second height by the first lifting device, when the receiving tank is at the first height, the height of the second feeding port is lower than the height of the reaction liquid outlet, at this time, the reaction liquid flows from the feeding tank to the receiving tank through the photochemical reactor, when the receiving tank is at the second height, the height of the second feeding port is higher than the height of the first feeding port, at this time, the reaction liquid flows back to the feeding tank from the receiving tank, and the next cycle is performed, the liquid level difference between the feeding tank and the receiving tank is changed, the continuous circulation of the reaction liquid is realized, and the technical problem that the peristaltic pump is used to realize the continuous circulation of the reaction liquid in the continuous flow photochemical reaction, the equipment cost is increased, the peristaltic pump is corroded due to the corrosion of the reaction liquid, the peristaltic pump is damaged, and the reaction is adversely affected or even forced to be interrupted in the prior art is solved. BRIEF DESCRIPTION OF DRAWINGS

[0020] In order to more clearly illustrate the technical scheme of the embodiments of the present application, the following will briefly introduce the drawings needed in the embodiment description. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, the elements or parts are not necessarily drawn according to the actual scale.

[0021] Figure 1 is a structure schematic view of the present application at the first height.

[0022] Figure 2 is a structure schematic view of the present application at the second height.

[0023] Main drawing mark explanation:

[0024] 10-feeding tank, 11-first feeding port, 12-first air pressure balance port, 13-first discharge port, 14-second lifting device, 20-photochemical reactor, 21-reaction liquid inlet, 22-reaction liquid outlet, 30-receiving tank, 31-second feeding port, 32-second air pressure balance port, 33-second discharge port, 40-first lifting device, 50-liquid inlet pipe, 60-liquid outlet pipe, 70-material transfer pipe, 80-air pressure balance pipe, 90-liquid level meter, 91-flow rate meter, 92-liquid inlet valve, 93-liquid outlet valve. DETAILED DESCRIPTION

[0025] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments of the present application, all the other embodiments obtained by those skilled in the art without creative work fall within the scope of the present application.

[0026] In the description of the present application, it should be noted that the directions or positional relationships indicated by the terms "center", "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "top", "bottom", "top surface", "bottom surface", "inner", "outer", "inner side", "outer side" are based on the directions or positional relationships shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and therefore cannot be understood as indicating or implying that the devices or elements indicated must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the present application.

[0027] In the description of the present application, the meaning of several is one or more, and the meaning of multiple is two or more. Greater than, less than, more than, etc. are understood as not including the number, and above, below, etc. are understood as including the number. If the terms "first", "second", "third" are described, they are only for the purpose of description and distinguishing technical features, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features or the sequence of indicated technical features.

[0028] In the description of the present application, it should be noted that, unless otherwise explicitly specified and limited, the terms "mounting", "connection", "connection", "setting" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the communication between two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances. The embodiments of the present application will be described below according to the overall structure of the present application.

[0029] As shown in Figure 1 and Figure 2 The present application provides a continuous flow photochemical reaction device, which comprises a feed tank 10, a photochemical reactor 20, a receiving tank 30, a first lifting device 40 and a control device.

[0030] The control device can be a PLC controller.

[0031] The feeding tank 10 is provided with a first feeding port 11 and a first air pressure balance port 12 at the top and a first discharging port 13 at the bottom, the photochemical reactor 20 is provided with a reaction liquid inlet 21 and a reaction liquid outlet 22, the heights of the reaction liquid inlet 21 and the reaction liquid outlet 22 are lower than the height of the first discharging port 13, the height of the reaction liquid inlet 21 is lower than the height of the reaction liquid outlet 22, the reaction liquid inlet 21 is connected with the first discharging port 13 through a liquid inlet pipe 50, at this time, the reaction liquid flows from the feeding tank 10 into the photochemical reactor 20, the receiving tank 30 is provided with a second feeding port 31 and a second air pressure balance port 32 at the top and a second discharging port 33 at the bottom, the second feeding port 31 is connected with the reaction liquid outlet 22 through a liquid outlet pipe 60, the second discharging port 33 is connected with the first feeding port 11 through a material transfer pipe 70, the second air pressure balance port 32 is connected with the first air pressure balance port 12 through an air pressure balance pipe 80, the first lifting device 40 is connected with the bottom end of the receiving tank 30 and is electrically connected with the control device, the control device is used for controlling the lifting of the first lifting device 40, the first lifting device 40 is used for periodically changing the height of the receiving tank 30 between a first height and a second height, when the receiving tank 30 is located at the first height, the height of the second feeding port 31 is lower than the height of the reaction liquid outlet 22, at this time, the reaction liquid flows from the photochemical reactor 20 into the receiving tank 30, when the receiving tank 30 is located at the second height, the height of the second discharging port 33 is higher than the height of the first feeding port 11, at this time, the reaction liquid flows from the receiving tank 30 back to the feeding tank 10 through the material transfer pipe 70 for the next cycle.

[0032] Specifically, the liquid inlet pipe 50, the liquid outlet pipe 60, the material transfer pipe 70 and the air pressure balance pipe 80 are all soft corrosion-resistant pipes, which can be polytetrafluoroethylene hoses, ethylene-propylene rubber hoses or polyurethane hoses, the first lifting device 40 is a scissor-type hydraulic lifting device, in order to facilitate the flow of the reaction liquid from the feeding tank 10 or the receiving tank 30, the bottom end of the feeding tank 10 and the receiving tank 30 is designed as a circular truncated cone structure, the end with a larger area of the circular truncated cone structure is located above the end with a smaller area, the first discharging port 13 and the second discharging port 33 are arranged at the end with a smaller area of the corresponding circular truncated cone structure.

[0033] In some preferred embodiments, a liquid level meter 90 is arranged in the feeding tank 10 and the receiving tank 30, and the liquid level meter 90 is electrically connected with the control device.

[0034] The liquid level in the feed tank 10 and the receiving tank 30 can be monitored in real time by arranging a liquid level gauge 90 in the feed tank 10 and the receiving tank 30, so that the first lifting device 40 is controlled by the control device to lift to move the receiving tank 30 between the first height and the second height, realizing the automatic circulation of the reaction liquid.

[0035] In some preferred embodiments, the bottom of the feed tank 10 is provided with a second lifting device 14, and the reaction liquid inlet 21 is provided with a flow rate meter 91, both of which are electrically connected to the control device. The second lifting device 14 is used to change the height of the feed tank 10, and the flow rate meter 91 is used to measure the flow rate of the reaction liquid flowing into the photochemical reactor 20.

[0036] The flow rate of the reaction liquid is monitored by the flow rate meter 91 and fed back to the control device, and the control device changes the height of the feed tank 10 according to the received flow rate information, so as to change the liquid level difference between the feed tank 10 and the photochemical reactor 20, thereby adjusting the flow rate of the reaction liquid into the photochemical reactor 20. In this embodiment, the second lifting device 14 is also a scissor-type hydraulic lifting device.

[0037] In some preferred embodiments, the reaction liquid inlet 21 is provided with a liquid inlet valve 92, and the reaction liquid outlet 22 is provided with a liquid outlet valve 93, both of which are electrically connected to the control device.

[0038] The flow rate of the reaction liquid flowing into the photochemical reactor 20 can be further adjusted downward by arranging the liquid inlet valve 92, and the on-off between the photochemical reactor 20 and the receiving tank 30 can be controlled by arranging the liquid outlet valve 93, thereby controlling the reaction time of the photochemical reaction.

[0039] In summary, the utility model discloses an embodiment provides a kind of applied to continuous flow photochemical reaction device, by setting the height of reaction liquid inlet and reaction liquid outlet is lower than the height of first liquid outlet, using air pressure balance pipe to connect feed tank and receiving tank, using first lifting device periodically makes the height of receiving tank between first height and second height change, when receiving tank is located first height, the height of second feed port is lower than the height of reaction liquid outlet, at this time, reaction liquid flows into receiving tank from feed tank through photochemical reactor, when receiving tank is located second height, the height of second discharge port is higher than the height of first feed port, at this time, reaction liquid flows back into feed tank from receiving tank, to be carried out next cycle, by changing the liquid level difference between feed tank and receiving tank, the continuous circulation of reaction liquid is realized, solve the technical problem in the prior art due to in continuous flow photochemical reaction using peristaltic pump to realize the continuous circulation of reaction liquid, not only increase equipment cost, and because reaction liquid usually has corrosive, can cause corrosion to each component of peristaltic pump, lead to peristaltic pump failure even damage, and then cause adverse effects on reaction even make reaction be forced to interrupt.

[0040] The foregoing description of specific exemplary embodiments of the present application is intended to be illustrative only and is not intended to be limiting as to the scope of the present application. It is apparent that various modifications and changes can be made to the specific embodiments described above without departing from the true spirit of the present application. Accordingly, it is intended that all such modifications and changes be included within the scope of the present application as set forth in the following claims.

Claims

1. A device for use in a continuous flow photochemical reaction apparatus, characterized in that, The device comprises a feeding tank (10), a photochemical reactor (20), a receiving tank (30), a first lifting device (40) and a control device; The feeding tank (10) is provided with a first feeding port (11) and a first air pressure balance port (12) on the top and a first discharging port (13) on the bottom; The photochemical reactor (20) is provided with a reaction liquid inlet (21) and a reaction liquid outlet (22), the height of the reaction liquid inlet (21) and the reaction liquid outlet (22) is lower than the height of the first discharging port (13), and the reaction liquid inlet (21) is connected with the first discharging port (13) through a liquid inlet pipe (50); The receiving tank (30) is provided with a second feeding port (31) and a second air pressure balance port (32) on the top and a second discharging port (33) on the bottom, the second feeding port (31) is connected with the reaction liquid outlet (22) through a liquid outlet pipe (60), the second discharging port (33) is connected with the first feeding port (11) through a material transfer pipe (70), and the second air pressure balance port (32) is connected with the first air pressure balance port (12) through an air pressure balance pipe (80); The first lifting device (40) is connected with the bottom end of the receiving tank (30) and is electrically connected with the control device, the first lifting device (40) is used for periodically moving the receiving tank (30) between a first height and a second height, when the receiving tank (30) is located at the first height, the height of the second feeding port (31) is lower than the height of the reaction liquid outlet (22), and when the receiving tank (30) is located at the second height, the height of the second discharging port (33) is higher than the height of the first feeding port (11).

2. The apparatus for continuous flow photochemical reaction according to claim 1, wherein The liquid inlet pipe (50), the liquid outlet pipe (60), the material transfer pipe (70) and the air pressure balance pipe (80) are soft corrosion-resistant pipes.

3. The apparatus for continuous flow photochemical reaction according to claim 1, wherein The feeding tank (10) and the receiving tank (30) are both provided with a liquid level meter (90), and the liquid level meter (90) is electrically connected with the control device.

4. The apparatus for continuous flow photochemical reaction according to claim 1, wherein The height of the reaction liquid inlet (21) is lower than the height of the reaction liquid outlet (22).

5. The apparatus for continuous flow photochemical reaction according to claim 1, wherein The bottom of the feeding tank (10) is provided with a second lifting device (14), the second lifting device (14) is electrically connected with the control device, and is used for changing the height of the feeding tank (10).

6. The apparatus for continuous flow photochemical reactions according to claim 5, wherein The first lifting device (40) and the second lifting device (14) are both scissor-type hydraulic lifting devices.

7. The apparatus for continuous flow photochemical reactions according to claim 5, wherein The reaction liquid inlet (21) is provided with a flowmeter (91), and the flowmeter (91) is electrically connected with the control device.

8. The apparatus for continuous flow photochemical reactions according to claim 1, wherein The bottom end of the feeding tank (10) and the receiving tank (30) is provided with a circular truncated cone structure, and the first discharging port (13) and the second discharging port (33) are both arranged at the end with a small area of the circular truncated cone structure.

9. The apparatus for continuous flow photochemical reactions according to claim 1, wherein The reaction liquid inlet (21) is provided with a liquid inlet valve (92), and the reaction liquid outlet (22) is provided with a liquid outlet valve (93), and the liquid inlet valve (92) and the liquid outlet valve (93) are both electrically connected with the control device.

Images