Sample analyzer
By designing the glycated blood glucose detection and routine blood test devices to be set at intervals in the sample analyzer, and by using the first and second power components in combination, the problems of slow sampling speed and inaccurate blood volume in the prior art are solved, and efficient and low-cost sample testing is achieved.
Patent Information
- Application Number
- CN202422926118.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-28
- Publication Date
- 2026-01-02
- Estimated Expiration
- 2034-11-28
AI Technical Summary
Existing integrated blood cell and glycated hemoglobin analyzers cannot balance instrument cost and testing efficiency, resulting in problems such as low sampling speed and inaccurate blood volume.
Design a sample analyzer that uses a glycation detection device and a blood routine detection device set alternately, and connects a sampling device with a sampling power device. Through the cooperation of the first and second power components, it can achieve efficient sample absorption and accurate distribution, reduce instrument cost and improve detection efficiency.
It improves the sampling efficiency and detection accuracy of the sample analyzer, reduces instrument costs, and enhances the user experience.
Smart Images

Figure CN223756752U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of blood detection, in particular to a sample analyzer. BACKGROUND
[0002] Glycated hemoglobin is relatively stable in structure and is commonly used as a monitoring index for diabetes control in clinical practice. At present, some manufacturers provide a pipeline including a blood cell analyzer and a glycated hemoglobin analyzer, a double-instrument device for blood cell analysis and glycated hemoglobin analysis, and further provide an all-in-one machine for blood cell and glycated hemoglobin detection to meet the demand for combined detection of blood routine and glycated hemoglobin. However, the existing all-in-one machine for blood cells and glycated hemoglobin often cannot balance the instrument cost and detection efficiency. CONTENT OF THE UTILITY MODEL
[0003] In order to solve the above technical problems, the present application provides a sample analyzer. The sample analyzer comprises a glycated hemoglobin detection device, a blood routine detection device, a sampling device and a sampling power device.
[0004] The glycated hemoglobin detection device and the blood routine detection device are arranged at intervals, the sampling device is connected with the sampling power device, and the sampling device and the sampling power device are arranged at intervals from the glycated hemoglobin detection device and the blood routine detection device.
[0005] The sampling device is used to provide a sample to be tested to the blood routine detection device and the glycated hemoglobin detection device.
[0006] The sampling power device comprises a first valve, a first power assembly and a second power assembly. The first power assembly is connected with the sampling device. The second power assembly is connected or disconnected with the first power assembly through the first valve.
[0007] When the first power assembly is connected with the second power assembly, the second power assembly is used to provide power for the sampling device to suck the sample to be tested.
[0008] When the first power assembly is disconnected with the second power assembly, the first power assembly is used to provide power for the sampling device to distribute the sample to be tested.
[0009] The capacity of the second power assembly is greater than or equal to the capacity of the first power assembly.
[0010] The sample analyzer further comprises a blood sedimentation detection device, and the blood sedimentation detection device is arranged on a connecting pipeline between the sampling device and the first power assembly.
[0011] The first valve is switched to make the first power assembly and the second power assembly communicate when the sample to be tested needs to be detected by the blood sedimentation detection device, and the second power assembly provides power to make the sample to be tested reach the corresponding pipeline section of the blood sedimentation detection device.
[0012] The capacity of the second power assembly is greater than or equal to 10 times the capacity of the first power assembly.
[0013] The capacity of the first power assembly is less than or equal to 250 μL, and the capacity of the second power assembly is less than or equal to 10 mL.
[0014] The glycation detection device comprises a glycation reaction pool, a glycation reagent assembly, a glycation power assembly, a second valve and a glycation detection assembly connected in sequence.
[0015] The glycation reaction pool is connected with the second valve through a first pipeline and is used to receive the sample to be tested injected by the sampling device.
[0016] The glycation power assembly is used to deliver the glycation hemolytic agent provided by the glycation reagent assembly to the glycation reaction pool through the second valve and the first pipeline, and deliver the sample to be tested and the glycation hemolytic agent after reaction to the glycation detection assembly through the first pipeline and the second valve.
[0017] The sample analyzer further comprises a third valve and a fourth valve.
[0018] The first end of the third valve is connected with the sampling device, and the second end of the third valve is connected with the sampling power device.
[0019] The first end of the fourth valve is connected with the glycation reaction pool, the second end of the fourth valve is connected with the second valve through the first pipeline, and the third end of the fourth valve is connected with the third end of the third valve.
[0020] The glycation power assembly is further used to deliver the sample to be tested to the glycation detection assembly through the third valve, the fourth valve and the second valve when the sample to be tested sucked by the sampling device is the sample to be tested after hemolysis reaction.
[0021] The glycation power assembly is further used to deliver the glycation hemolytic agent provided by the glycation reagent assembly to the sampling device through the second valve, the fourth valve and the third valve.
[0022] The sample analyzer further comprises a fifth valve, the first end of the fifth valve is connected with the glycation reaction pool, and the second end of the fifth valve is connected with the first end of the second valve through the first pipeline.
[0023] To solve the above technical problems, the application further provides another sample analyzer, which comprises a glycated hemoglobin detection device, a blood routine detection device, a specific protein detection device, a blood sedimentation detection device, a sampling device and a sampling power device;
[0024] The glycated hemoglobin detection device, the blood routine detection device, the specific protein detection device and the blood sedimentation detection device are arranged at intervals, the sampling device is connected with the sampling power device and arranged at intervals with the glycated hemoglobin detection device, the blood routine detection device, the specific protein detection device and the blood sedimentation detection device;
[0025] The sampling power device is used to provide power for the sampling device to suck and discharge the sample to be tested; the sampling device is used to provide the sample to be tested to the glycated hemoglobin detection device, the blood routine detection device, the specific protein detection device and the blood sedimentation detection device.
[0026] To solve the above technical problems, the application further provides a sample analyzer, which comprises a glycated hemoglobin detection device, a blood routine detection device and a sampling device; the sampling device, the glycated hemoglobin detection device and the blood routine detection device are arranged at intervals;
[0027] The sampling device is used to provide the sample to be tested to the reaction pool of the blood routine detection device and the glycated hemoglobin detection device;
[0028] The glycated hemoglobin detection device comprises a glycated hemoglobin reaction pool, a glycated hemoglobin reagent assembly, a glycated hemoglobin power assembly, a second valve and a glycated hemoglobin detection assembly connected in sequence; the glycated hemoglobin reaction pool is connected with the second valve through a first pipeline;
[0029] The glycated hemoglobin power assembly is used to transport the glycated hemolysis agent provided by the glycated hemoglobin reagent assembly to the glycated hemoglobin reaction pool through the first pipeline, and transport the sample to be tested and the glycated hemolysis agent after reaction to the glycated hemoglobin detection assembly through the first pipeline and the second valve.
[0030] The beneficial effects of the present application: different from the prior art, the sample analyzer provided by the present application comprises a glycosylation detection device, a routine blood detection device, a sampling device and a sampling power device, the glycosylation detection device and the routine blood detection device are arranged at intervals, the sampling device is connected with the sampling power device and arranged at intervals with the glycosylation detection device and the routine blood detection device, and the sampling device is used to provide the routine blood detection device and the glycosylation detection device with a sample to be tested, thereby improving the practicability of the sampling device. The sampling power device comprises a first valve, a first power assembly and a second power assembly, the first power assembly is connected with the sampling device, the second power assembly is connected with the first power assembly through the first valve or disconnected; when the first power assembly is connected with the second power assembly, the second power assembly is used to provide power for the sampling device to suck the sample to be tested; when the first power assembly is disconnected from the second power assembly, the first power assembly is used to provide power for the sampling device to distribute the sample to be tested, wherein the capacity of the second power assembly is greater than or equal to the capacity of the first power assembly. Through the cooperation of the first power assembly and the second power assembly, the sampling efficiency of the sampling device on the sample to be tested can be improved while reducing the cost of the instrument, the accuracy of the sampling device in distributing the sample to be tested to the routine blood detection device and the glycosylation detection device can be improved, and the practicability of the sample analyzer can be improved. BRIEF DESCRIPTION OF DRAWINGS
[0031] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed in the embodiment description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.
[0032] Among them:
[0033] Figure 1 is a structural schematic diagram of the first embodiment of the sample analyzer of the present application;
[0034] Figure 2 is a structural schematic diagram of an embodiment of the sampling power device of the present application;
[0035] Figure 3 is a structural schematic diagram of an embodiment of the glycosylation detection device of the present application;
[0036] Figure 4 is a structural schematic diagram of the second embodiment of the sample analyzer of the present application;
[0037] Figure 5 is a structural schematic diagram of the third embodiment of the sample analyzer of the present application;
[0038] Figure 6 is a structural schematic diagram of another embodiment of the glycosylation detection device of the present application;
[0039] Figure 7 This is a schematic diagram of the fourth embodiment of the sample analyzer of this application.
[0040] Reference numerals in the figures: Sample analyzer 1; Glycation detection device 11; Glycation reaction tank 111; Glycation reagent assembly 112; Glycation power assembly 113; Second valve 114; Glycation detection assembly 115; First pipeline 116; High pressure build-up assembly 117; Complete blood count device 12; Sampling device 13; Sampling power unit 14; First valve 141; First power assembly 142; Second power assembly 143; Erythrocyte sedimentation rate (ESR) detection device 15; Third valve 16; Fourth valve 17; Fifth valve 18; Specific protein detection device 19. Detailed Implementation
[0041] The embodiments of this application will now be described in detail with reference to the accompanying drawings.
[0042] In the following description, specific details such as particular system architectures, interfaces, and technologies are presented for illustrative purposes rather than for limiting purposes, in order to provide a thorough understanding of this application.
[0043] In this application, the reference to "embodiment" means that a specific feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this application. The appearance of this phrase in various places throughout the specification does not necessarily refer to the same embodiment, nor is it a separate or alternative embodiment mutually exclusive with other embodiments. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.
[0044] In this application, the term "and / or" is merely a description of the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent three cases: A alone, A and B simultaneously, and B alone. Additionally, the character " / " generally indicates that the preceding and following related objects are in an "or" relationship. Furthermore, "many" in this application means two or more. Moreover, the term "at least one" in this application means any combination of at least two of any one or more of a plurality of objects. For example, including at least one of A, B, and C can mean including any one or more elements selected from the set consisting of A, B, and C. Furthermore, the terms "first," "second," and "third" in this application are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features.
[0045] Please see Figure 1 , Figure 1is a structural schematic diagram of a first embodiment of a sample analyzer of the present application. The sample analyzer 1 provided in the embodiment of the present application comprises a glycation detection device 11, a blood routine detection device 12, a sampling device 13, and a sampling power device 14. The glycation detection device 11 can perform glycation detection on a sample to be tested, and is used to detect glycosylated hemoglobin in the sample to be tested, so as to reflect the blood glucose level of the sample to be tested. The blood routine detection device 12 can perform blood routine detection on the sample to be tested, and is used to detect red blood cells, white blood cells, and platelet systems, and detect cells in the sample to be tested.
[0046] The glycation detection device 11 is arranged apart from the blood routine detection device 12. The sampling device 13 is connected to the sampling power device 14 and arranged apart from the glycation detection device 11 and the blood routine detection device 12. The sampling device 13 is used to provide the sample to be tested to the blood routine detection device 12 and the glycation detection device 11. The glycation detection device 11 and the blood routine detection device 12 receive the sample to be tested distributed by the sampling device 13, and can use the sample to be tested to perform corresponding detection, thereby improving the detection efficiency of the sample analyzer 1.
[0047] The sample to be tested can be a blood sample, a body fluid sample (such as cerebrospinal fluid, pleural fluid, and ascites), or the like.
[0048] Further, please continue to refer to Figure 2 , Figure 2 is a structural schematic diagram of an embodiment of a sampling power device of the present application. The sampling power device 14 provided in the embodiment comprises a first valve 141, a first power assembly 142, and a second power assembly 143.
[0049] The first power assembly 142 is connected to the sampling device 13. The second power assembly 143 is connected to or disconnected from the first power assembly 142 through the first valve 141. The capacity of the second power assembly 143 is greater than or equal to the capacity of the first power assembly 142. The first power assembly 142 and the second power assembly 143 can be syringes with different capacities.
[0050] Specifically, when the first power assembly 142 and the second power assembly 143 are connected, the second power assembly 143 is used to provide power for the sampling device 13 to suck the sample to be tested. When the first power assembly 142 and the second power assembly 143 are disconnected, the first power assembly 142 is used to provide power for the sampling device 13 to distribute the sample to be tested.
[0051] The sampling device 13 can provide the blood routine detection device 12 and the glycation detection device 11 with the sample to be detected, that is, the sampling device 13 can suck the sample to be detected in a one-time manner when collecting the sample to be detected, and then move to the glycation detection device 11 and the blood routine detection device 12 to distribute the corresponding sample to be detected. Therefore, during the process of sucking the sample to be detected by the sampling device 13, the second power assembly 143 with a larger capacity can be used to provide power, so as to improve the sucking efficiency of the sampling device 13 on the sample to be detected. When the sampling device 13 distributes the sample to be detected to the glycation detection device 11 and the blood routine detection device 12, since the amount of the sample to be detected injected into the glycation detection device 11 and the blood routine detection device 12 needs to be accurate, the first power assembly 142 with a smaller capacity is used to provide power for the sampling device 13 to distribute the sample to be detected, so as to improve the accuracy of the sampling device. The technical scheme provided in the embodiment of the application can solve the problems of low blood sampling speed and inaccurate blood distribution caused by using the same sampling needle and syringe to collect blood routine samples and glycation samples in the blood cell and glycosylated hemoglobin integrated machine, or the problems of high cost and complex instrument control caused by using two sets of sampling needles and syringes to collect blood routine samples and glycation samples in the blood cell and glycosylated hemoglobin integrated machine; the sucking efficiency of the sampling device on the sample to be detected can be improved while reducing the cost of the instrument, and the accuracy of the sampling device in distributing the sample to be detected to the blood routine detection device and the glycation detection device can be improved, thereby improving the practicability of the sample analyzer.
[0052] In an embodiment, if the first power assembly 142 is used to provide power for the sampling device 13 to suck the sample to be detected, since the capacity of the first power assembly 142 is small, the collection efficiency of the sampling device 13 on the sample to be detected is reduced, and the running efficiency of the sample analyzer 1 is affected. During the process of distributing the sample to be detected by the sampling device 13, if the second power assembly 143 is used to provide power, since the capacity of the second power assembly 143 is large, the sampling device 13 may inject an excessive amount of the sample to be detected into the glycation detection device 11 and the blood routine detection device 12, which affects the detection efficiency of the glycation detection device 11 and the blood routine detection device 12 on the sample to be detected, and reduces the detection efficiency of the sample analyzer 1.
[0053] In another embodiment, during the process of sucking the sample to be detected by the sampling device 13, the first power assembly 142 and the second power assembly 143 can be used to provide power for the sampling device 13 at the same time, so as to further improve the sucking efficiency of the sampling device 13 on the sample to be detected.
[0054] Optionally, as shown in FIG. 6, the first power assembly 142 and the second power assembly 143 can be arranged in the sampling device 13 in a staggered manner. Figure 1 and Figure 2As shown, the sample analyzer 1 can further include a blood sedimentation detection device 15 arranged on the connecting pipeline between the sampling device 13 and the first power assembly 142. The blood sedimentation detection device 15 can perform blood sedimentation detection on the sample to be tested, for detecting the erythrocyte sedimentation rate in the blood sample.
[0055] Specifically, when the sample to be tested needs to be subjected to blood sedimentation detection, the first valve 141 is switched to enable the first power assembly 142 and the second power assembly 143 to communicate, and the second power assembly 143 provides power to enable the sample to be tested to reach the pipeline segment corresponding to the blood sedimentation detection device 15.
[0056] Since the blood sedimentation detection device 15 is arranged on the connecting pipeline between the sampling device 13 and the first power assembly 142, that is, when the sample to be tested needs to be subjected to blood sedimentation detection, the sample to be tested needs to be sucked to the pipeline segment corresponding to the blood sedimentation detection device 15. As described above, the capacity of the second power assembly 143 is greater than that of the first power assembly 142, and therefore, the first valve 141 can be switched to enable the first power assembly 142 and the second power assembly 143 to communicate. The second power assembly 143 can communicate with the pipeline segment corresponding to the blood sedimentation detection device 15 through the first valve 141 and the first power assembly 142, and can provide power to the sampling device 13 to accelerate the efficiency of the sample to be tested being sucked to the pipeline segment corresponding to the blood sedimentation detection device 15, and to effectively disperse the blood sedimentation sample through greater power to improve the accuracy of blood sedimentation detection.
[0057] In an embodiment, after the first valve 141 is switched to enable the first power assembly 142 and the second power assembly 143 to communicate, the first power assembly 142 and the second power assembly 143 can simultaneously provide power to the sampling device 13 to further improve the efficiency of the sample to be tested being sucked.
[0058] In summary, by arranging the first valve 141, the first power assembly 142 and the second power assembly 143, the efficiency of the sample to be tested being sucked by the sampling device 13 can be improved, and the accuracy and efficiency of the sample to be tested being distributed by the sampling device 13 can be improved, the operation efficiency and practicability of the sample analyzer 1 can be improved, and the user experience of the sample analyzer 1 can be improved.
[0059] In the case that the sample to be tested needs to be detected for glycosylation, blood routine examination and blood sedimentation, since the time required for blood sedimentation of the sample to be tested is relatively long, in order to further improve the detection efficiency of the sample analyzer 1, the sampling device 13 can first sample the sample to be tested at the glycosylation detection device 11 and the blood routine examination device 12, and then use the remaining sample to be tested in the pipeline between the sampling device 13 and the first power assembly 142 for blood sedimentation detection, so as to avoid waiting for the blood sedimentation detection of the sample to be tested to be completed before the glycosylation detection and blood routine examination in the sample analyzer 1, thereby improving the detection efficiency of the sample analyzer 1.
[0060] It can be understood that, compared to first performing blood sedimentation detection and then performing other item detection, more sample to be tested is required for first performing other item detection and then performing blood sedimentation detection, that is, if blood sedimentation detection is performed first and then other item detection is performed, the sample to be tested after blood sedimentation detection can be sampled by the sampling device 13 to other detection devices for other item detection; and if other item detection is performed first and then blood sedimentation detection is performed, the sampling device 13 needs to collect enough sample to be tested (at least including the total of the amount of sample to be tested required for glycosylation detection, the amount of sample to be tested required for blood routine examination, and the amount of sample to be tested required for blood sedimentation detection), so as to ensure that there is still sufficient sample to be tested in the pipeline between the sampling device 13 and the first power assembly 142 for blood sedimentation detection after sampling the sample to be tested to the glycosylation detection device 11 and the blood routine examination device 12. The specific detection sequence can be set by the user, and the present application does not limit this.
[0061] In other embodiments, the detection time period of the sample analyzer 1 for glycosylation detection and blood routine examination of the sample to be tested can be partially overlapped or not overlapped. For example but not limited to, the glycosylation detection device 11 and the blood routine examination device 12 are arranged in sequence away from the sampling device 13, then after the sampling device 13 collects the sample to be tested, it is first moved to the glycosylation detection device 11 for sampling, after the glycosylation detection device 11 receives the sample to be tested, it starts to detect the sample to be tested for glycosylation; then the sampling device 13 moves to the blood routine examination device 12 for sampling, after the blood routine examination device 12 receives the sample to be tested, it performs blood routine examination, if the glycosylation detection in the glycosylation detection device 11 is not completed at this time, the detection time period of the glycosylation detection and the blood routine examination of the sample to be tested is partially overlapped; and if the glycosylation detection in the glycosylation detection device 11 is completed at this time, the detection time period of the glycosylation detection and the blood routine examination of the sample to be tested is not overlapped.
[0062] It can be understood that whether the detection time period of each item detection of the sample to be tested in the sample analyzer 1 is overlapped or not can depend on the detection duration of each detection device for the sample to be tested, and the time sequence of the sampling device 13 for sampling the sample to be tested, which is not limited by the present application.
[0063] Optionally, the capacity of the second power component 143 is greater than or equal to 10 times the capacity of the first power component 142, so as to further accelerate the sampling efficiency of the sampling device 13 on the sample to be tested, and improve the accuracy of the sampling device 13 in dispensing the sample to be tested.
[0064] In an embodiment, the volume of the first power component 142 is less than or equal to 250 μL, such as 100 μL, 125 μL, 200 μL, 250 μL, etc.; and the capacity of the second power component 143 is less than or equal to 10 mL, such as 1 mL, 2.5 mL, 5 mL, 7 mL, 10 mL, etc.
[0065] In another embodiment, the specific capacity of the first power component 142 and the second power component 143 can also be set according to the amount of sample to be tested required by the sugar detection device 11, the blood routine detection device 12, the blood sedimentation detection device 15 and other detection devices, which is not limited in the present application.
[0066] Optionally, the volume of the connecting pipeline between the sampling device 13 and the first power component 142 is less than or equal to 1.5 mL, and the inner diameter of the pipeline is less than 1.2 mm.
[0067] In the above, the blood sedimentation detection device 15 is arranged on the connecting pipeline between the sampling device 13 and the first power component 142. The detection principle of the blood sedimentation detection device 15 is that the light beam emitted by the blood sedimentation detection device 15 is incident on a fixed section of the connecting pipeline between the sampling device 13 and the first power component 142, so as to irradiate the sample to be tested in the pipeline. Then the blood sedimentation detection device 15 recovers the light beam, and obtains the erythrocyte sedimentation rate in the sample to be tested, i.e. the blood sedimentation detection result of the cell to be tested, by analyzing the information of the light beam.
[0068] Therefore, the present application limits the volume of the connecting pipeline between the sampling device 13 and the first power component 142 to be less than or equal to 1.5 mL, and limits the inner diameter of the pipeline to be less than 1.2 mm, so as to reduce the use amount of the sample to be tested in the blood sedimentation detection process of the blood sedimentation detection device 15, reduce the reagent cost, and reduce the negative pressure of the end of the sampling device 13 away from the sampling power device 14 during sampling, thereby improving the safety of the sample analyzer 1.
[0069] Understandably, given the limited volume of the connecting pipe between the sampling device 13 and the sampling power device 14, if the total amount of sample to be tested in the glycated glucose detection device 11 and the complete blood count detection device 12 is less than 1.5 mL, the sampling device 13 can aspirate a sufficient amount of sample at once and transport it sequentially to the glycated glucose detection device 11 and the complete blood count detection device 12. However, if the total amount of sample to be tested in the glycated glucose detection device 11 and the complete blood count detection device 12 is greater than 1.5 mL, the sampling device 13 can deliver the sample to the glycated glucose detection device 11 and the complete blood count detection device 12 in multiple batches. That is, this application does not limit the number of times the sampling device 13 samples the glycated glucose detection device 11 and the complete blood count detection device 12; this number can be determined by the user's settings, the volume of the connecting pipe, and the amount of sample required by the device.
[0070] In one embodiment, before the sampling device 13 picks up the sample to be tested, the connecting pipe between the sampling device 13 and the sampling power device 14 is filled with a liquid such as a diluent to keep the pipe moist and prevent it from drying out and causing damage. For example, Figure 2 As shown, the third end of the first valve 141 can be connected to a diluent supply component, thereby the first valve 141 can switch the connection between the first power component 142 and the diluent supply component, and the first power component 142 fills the connection pipeline between the first power component 142 and the sampling device 13 with the diluent in the diluent supply component.
[0071] Before the sampling device 13 absorbs the sample to be tested, an air section can be drawn first, and then the sample to be tested can be drawn. The air section can isolate the sample to be tested from the diluent in the original pipeline, avoid the diluent from contacting the sample to be tested, avoid reagent contamination, and improve the safety and operating efficiency of the sample analyzer 1.
[0072] Optionally, such as Figure 3 As shown, Figure 3 This is a schematic diagram of the structure of an embodiment of the saccharification detection device of this application. The saccharification detection device 11 provided in this application includes a saccharification reaction tank 111, a saccharification reagent assembly 112, a saccharification power assembly 113, a second valve 114, and a saccharification detection assembly 115 connected in sequence.
[0073] The glycation reaction tank 111 is connected to the second valve 114 via the first pipeline 116 and is used to receive the sample to be tested injected by the sampling device 13. The glycation power unit 113 is used to transport the glycation lysing agent provided by the glycation reagent unit 112 to the glycation reaction tank 111 via the second valve 114 and the first pipeline 116, and to transport the test solution obtained after the reaction of the sample to be tested and the glycation lysing agent to the glycation detection unit 115 via the first pipeline 116 and the second valve.
[0074] Specifically, the second valve 114 can be a three-way valve. After the saccharification reaction pool 111 receives the sample to be tested injected by the sampling device 13, the second valve 114 can be switched to connect the saccharification reagent assembly 112 and the saccharification reaction pool 111. Then, the saccharification hemolysin in the saccharification reagent assembly 112 will enter the saccharification reaction pool 111 through the second valve 114 and the first pipeline 116 under the action of the saccharification power assembly 113, and mix with the sample to be tested in the saccharification reaction pool 111 to form the test solution.
[0075] Furthermore, the second valve 114 can also be switched to connect the saccharification reaction tank 111 and the saccharification detection component 115. The test liquid in the saccharification reaction tank 111 then enters the saccharification detection component 115 for saccharification detection via the first pipeline 116 and the second valve 114.
[0076] In one embodiment, such as Figure 4 As shown, Figure 4 This is a schematic diagram of the structure of the sample analyzer of the present application in the second embodiment. The glycation detection component 115 may include a chromatography column and a detector. The chromatography column is used to separate glycated hemoglobin from hemoglobin in the test solution to obtain a test sample containing glycated hemoglobin. The detector is used to detect glycated hemoglobin in the test sample to perform glycation detection on the test solution.
[0077] By coordinating the saccharification power unit and the second valve 114, the saccharification lysing agent and the test solution can flow in the first pipeline 116. There is no need to set up an additional power unit or liquid pipeline to inject the saccharification lysing agent into the saccharification reaction pool 111 or to move the test solution in the saccharification reaction pool 111 to the saccharification detection unit 115. This simplifies the device setup of the saccharification detection device 11, simplifies the pipeline structure, reduces costs, and improves the transport efficiency of reagents in the saccharification detection device 11.
[0078] Optionally, such as Figure 4 As shown, the second valve 114 can also be a six-way valve. The saccharification reaction tank 111 is connected to the first end of the six-way valve. The saccharification reagent assembly 112 is connected to the second end of the six-way valve through the saccharification power assembly 113. The saccharification power assembly 113 is also connected to the third end of the six-way valve. The saccharification detection assembly 115 is connected to the fourth end of the six-way valve.
[0079] For clarity, Figure 4 The first end of the six-way valve is marked "1", the second end is marked "2", the third end is marked "3", and the fourth end is marked "4".
[0080] Specifically, the six-way valve includes a metering ring, with its two ends connected to the fifth end of the six-way valve. Figure 4 The middle mark "5") and the sixth end of the six-way valve (Figure 4 The six-way valve is configured to have a first state and a second state, connected by the "6" mark in the middle.
[0081] like Figure 4 As shown, when the six-way valve is in its first state, the first end of the six-way valve is connected to the second end, the fourth end to the fifth end, and the third end to the sixth end. At this time, the third and fourth ends of the six-way valve are connected to the metering ring. When the six-way valve is in its second state, the first end is connected to the fifth end, the second end to the sixth end, and the third end to the fourth end. At this time, the metering ring is connected to both the first and second ends of the six-way valve.
[0082] When the six-way valve is in its first state, the glycated hemolysin in the glycated reagent assembly 112 can be injected into the glycated reaction chamber 111 through the glycated power assembly 113 and the six-way valve. The sample to be tested in the glycated reaction chamber 111 can be mixed with the glycated hemolysin to obtain the test solution, which can then fill the tubing between the first and second ends of the six-way valve. When the six-way valve is switched to its second state, the first and second ends of the six-way valve are connected to the metering loop, meaning that the test solution in the tubing between the first and second ends of the six-way valve can fill the metering loop. In this step, the glycated power assembly 113 can provide power to the second end of the six-way valve to assist the test solution in the tubing between the first and second ends of the six-way valve into the metering loop.
[0083] After the test solution is filled into the quantitative loop, the six-way valve switches back to the first state. At this time, the third and fourth ends of the six-way valve are connected to the quantitative loop. The saccharification power assembly 113 can provide power to the third end of the six-way valve so that the test solution in the quantitative loop enters the saccharification detection assembly 115 through the fourth end of the six-way valve for saccharification detection.
[0084] In other embodiments, the second valve 114 may also be a valve with other specific structures, which is not limited in this application.
[0085] Alternatively, please continue reading Figure 4 The sample analyzer 1 also includes a third valve 16 and a fourth valve 17. The first end of the third valve 16 is connected to the sampling device 13, and the second end of the third valve 16 is connected to the sampling power device 14; the first end of the fourth valve 17 is connected to the saccharification reaction tank 111, the second end of the fourth valve 17 is connected to the second valve 114 through the first pipeline 116, and the third end of the fourth valve 17 is connected to the third end of the third valve 16.
[0086] Further, when the sample to be tested injected into the saccharification reaction pool 111 by the sampling device 13 is the sample to be tested after the hemolysis reaction is completed, the saccharification power assembly 113 is further configured to deliver the sample to be tested to the saccharification detection assembly 115 through the third valve 16, the fourth valve 17 and the second valve 114.
[0087] When the sample to be tested injected into the saccharification reaction pool 111 by the sampling device 13 is the sample to be tested before the hemolysis reaction is completed, the saccharification power assembly 113 is further configured to deliver the saccharification hemolysis agent provided by the saccharification reagent assembly 112 to the sampling device 13 through the second valve 114, the fourth valve 17 and the third valve 16.
[0088] Specifically, as shown in FIG. 2, the second valve 114 is a six-way valve, and the sample to be tested collected by the sampling device 13 is the sample to be tested before the hemolysis reaction is completed. The saccharification detection device 11 performs saccharification detection on the sample to be tested as follows: Figure 5
[0089] The first end and the second end of the third valve 16 are communicated, the sampling power device 14 provides negative pressure to the sampling device 13, the sampling device 13 samples the sample to be tested, and then the sampling device 13 moves to the saccharification reaction pool 111, the sampling power device 14 provides positive pressure to the sampling device 13, so that the sample to be tested in the sampling device 13 enters the saccharification reaction pool 111.
[0090] After the sample to be tested is injected into the saccharification reaction pool 111, the first end and the third end of the fourth valve 17 are communicated, the six-way valve is switched to the first state, the first end and the third end of the third valve 16 are communicated, and at this time, under the action of the saccharification power assembly 113, the saccharification hemolysis agent in the saccharification reagent assembly 112 enters the saccharification reaction pool 111 through the second end of the six-way valve-the first end of the six-way valve-the first end of the fourth valve 17-the third end of the fourth valve 17-the third end of the third valve 16-the first end of the third valve 16-the sampling device 13. At this time, the sample to be tested and the saccharification hemolysis agent in the saccharification mixing pool 111 are mixed to form the sample to be tested.
[0091] In an embodiment, the first end and the second end of the fourth valve 17 are communicated, the six-way valve is switched to the first state, and further, under the action of the saccharification power assembly 113, the saccharification hemolysis agent in the saccharification reagent assembly 112 enters the saccharification reaction pool 111 through the second end of the six-way valve-the first end of the six-way valve-the first end of the fourth valve 17-the second end of the fourth valve 17.
[0092] In another embodiment, the sample analyzer 1 further comprises a mixing assembly (not shown in the figure) which can be arranged separately from the saccharification reaction pool 111 to mix the sample to be tested and the saccharification lysing agent in the saccharification reaction pool 111. In other embodiments, the sampling device 13 can be moved to the saccharification reaction pool 111 at one end, the third valve 16 is switched to connect the first end and the second end, and then the sampling power device 14 provides a force to the sampling device 13 to repeatedly suck and spit the mixed liquid of the sample to be tested and the saccharification lysing agent, so as to mix the sample to be tested and the saccharification lysing agent to form the sample to be tested. The mixing operation of the sample to be tested and the saccharification lysing agent in the saccharification reaction pool 111 is not limited in the present application. In the embodiment of the present application, the saccharification power assembly can also be used to suck and spit the mixed liquid in the reaction pool 111 to obtain the sample to be tested.
[0093] After obtaining the sample to be tested in the saccharification reaction pool 111, the third valve 16 can be switched to connect the third end and the first end, the fourth valve 17 is switched to connect the first end and the third end, the sampling device 13 is moved into the saccharification reaction pool 111, and the post-saccharification power assembly 113 provides negative pressure to the second end of the six-way valve to inject the sample to be tested in the saccharification reaction pool 111 into the pipeline between the first end and the second end of the six-way valve through the sampling device 13-the first end of the third valve 16-the third end of the third valve 16-the third end of the fourth valve 17-the first end of the fourth valve 17-the first end of the six-way valve.
[0094] In an embodiment, the fourth valve 17 can be switched to connect the first end and the second end, and the post-saccharification power assembly 113 provides negative pressure to the second end of the six-way valve to inject the sample to be tested in the saccharification reaction pool 111 into the pipeline between the first end and the second end of the six-way valve through the second end of the fourth valve 17-the first end of the fourth valve 17-the first end of the six-way valve.
[0095] Then the six-way valve is switched to the second state, and the sample to be tested in the pipeline between the first end and the second end of the six-way valve is filled into the metering ring. After the sample to be tested is filled in the metering ring, the six-way valve is switched to the first state again, and the saccharification power assembly 113 provides positive pressure to the third end of the six-way valve. Under the action of the positive pressure, the sample to be tested in the metering ring enters the saccharification detection assembly 115 through the fourth end of the six-way valve for saccharification detection.
[0096] When the six-way valve is switched to the first state for the second time, the sixth end of the six-way valve is in communication with the third end of the six-way valve, the fifth end of the six-way valve is in communication with the fourth end of the six-way valve, that is, the first end of the six-way valve and the second end of the six-way valve are irrelevant to the subsequent saccharification detection process. At this time, the saccharification lysing agent in the saccharification reagent assembly 112 can enter the sampling device 13 under the action of the saccharification power assembly 113, through the second end of the six-way valve-the first end of the six-way valve-the first end of the fourth valve 17-the third end of the fourth valve 17-the third end of the third valve 16-the first end of the third valve 16, to clean the inner wall of the sampling device 13. That is, the sampling device 13 can be cleaned during the detection of the sample liquid by the saccharification detection assembly 115, avoiding the contamination of the sampling device 13 by the reagent, and improving the operation efficiency of the combined detection equipment A.
[0097] Further, the sampling device 13 can be moved to the waste liquid pool. After the saccharification lysing agent cleans the inner wall of the sampling device 13, it can directly enter the waste liquid pool. In another embodiment, the sampling device 13 can still stay in the saccharification reaction pool 111 after absorbing the sample liquid. After the saccharification lysing agent cleans the inner wall of the sampling device 13, it can enter the saccharification reaction pool 111 to clean the saccharification reaction pool 111.
[0098] In other embodiments, the cleaning of the inner wall of the sampling device 13 can also be performed after the saccharification detection assembly 115 completes the detection of the sample liquid. The sample analyzer 1 can clean the saccharification detection device 11 and the sampling device 13 uniformly.
[0099] In another embodiment, the second valve 114 is a six-way valve, and the sample collected by the sampling device 13 is a sample liquid that has completed the hemolysis reaction. The saccharification detection process of the saccharification detection device 11 on the sample is as follows:
[0100] When the sample to be tested needs to be detected for glycation, the first end and the third end of the fourth valve 17 are communicated, the six-way valve is switched to the first state, the first end and the third end of the third valve 16 are communicated, at this time, under the action of the glycation power assembly 113, the glycation lysing agent in the glycation reagent assembly 112 reaches the sampling device 13 through the second end of the six-way valve-the first end of the six-way valve-the first end of the fourth valve 17-the third end of the fourth valve 17-the third end of the third valve 16-the first end of the third valve 16, and at this time the sampling device 13 can be moved outside the sample analyzer 1, that is, the glycation lysing agent inside the sample analyzer 1 can be transported outside the machine to mix with the sample to be tested outside the machine to form a sample to be tested after the hemolysis reaction. When receiving the sample to be tested after the hemolysis reaction, the sampling device 13 can be lowered to the sample tube to collect the sample to be tested after the hemolysis reaction, and under the power provided by the glycation power assembly 113, the sample to be tested after the hemolysis reaction is transported to the glycation detection assembly 115 through the third valve 16, the fourth valve 17 and the second valve 114 for glycation detection. By transporting the glycation lysing agent outside the machine to mix with the sample to be tested, the mixing efficiency of the glycation lysing agent and the sample to be tested can be ensured, and the detection efficiency of the glycation detection device 11 can be improved.
[0101] Optionally, please refer to Figure 5 , Figure 6 is a structural schematic diagram of the third embodiment of the sample analyzer. The sample analyzer 1 further comprises a fifth valve 18, the first end of the fifth valve 18 is connected with the glycation reaction pool 111, and the second end of the fifth valve 18 is connected with the first end of the second valve 114 through the first pipeline 116.
[0102] Specifically, taking the second valve 114 as a six-way valve as an example, the second end of the fifth valve 18 is connected with the first end of the six-way valve through the first pipeline 116. The detection process of the glycation detection device 11 on the sample to be tested is as follows:
[0103] Under the action of the sampling power device 14, the sampling device 13 collects the sample to be tested and injects the sample to be tested into the glycation reaction pool 111.
[0104] Then the first end and the second end of the fifth valve 18 are communicated, the six-way valve is switched to the first state, the saccharifying reagent in the saccharifying reagent assembly 112 is under the action of the saccharifying power assembly 113, enters the saccharifying reaction tank 111 through the second end of the six-way valve-the first end of the six-way valve-the second end of the fifth valve 18-the first end of the fifth valve 18, is mixed with the sample in the saccharifying reaction tank 111, and the sample is obtained. After the sample is obtained in the saccharifying reaction tank 111, the saccharifying power assembly 113 can apply negative pressure to the second end of the six-way valve, and then the sample in the saccharifying reaction tank 111 enters the pipeline between the first end and the second end of the six-way valve through the first end of the fifth valve 18-the second end of the fifth valve 18-the first end of the six-way valve.
[0105] The six-way valve is switched to the second state, and the sample in the pipeline between the first end and the second end of the six-way valve is filled into the quantitative ring. After the quantitative ring is filled with the sample, the six-way valve is switched to the first state again, and under the action of the saccharifying power assembly 113, the sample in the quantitative ring enters the saccharifying detection assembly 115 through the fourth end of the six-way valve for saccharifying detection.
[0106] When the six-way valve is switched to the first state for the second time, since the sixth end of the six-way valve is communicated with the third end of the six-way valve, and the fifth end of the six-way valve is communicated with the fourth end of the six-way valve, that is, the first end of the six-way valve and the second end of the six-way valve are irrelevant to the subsequent process of saccharifying detection, at this time, the saccharifying reagent in the saccharifying reagent assembly 112 can enter the saccharifying reaction tank 111 under the action of the saccharifying power assembly 113 through the second end of the six-way valve-the first end of the six-way valve-the second end of the fifth valve 18-the first end of the fifth valve 18. And one end of the sampling device 13 moves into the saccharifying reaction tank 111, under the action of the sampling power device 14, the sampling device 13 can suck the saccharifying reagent in the saccharifying reaction tank 111 to clean the inner wall of the sampling device 13.
[0107] It can be understood that the cleaning of the inner wall of the sampling device 13 can also be after the saccharifying detection assembly 115 completes the detection of the sample, the sample analyzer 1 uniformly cleans the saccharifying detection device 11 and the sampling device 13.
[0108] Compared with the embodiment that the sample analyzer 1 includes the third valve 16 and the fourth valve 17, the embodiment that the sample analyzer 1 only includes the fifth valve 18 can reduce the participation rate of the sampling device 13 in the saccharifying detection process of the saccharifying detection device to the sample, so as to reduce the loss of the sampling device 13 and improve the operation efficiency of the sample analyzer 1.
[0109] Optionally, the saccharification reaction tank 111 is connected with the fourth valve 17 or the connection of the fifth valve 18 can be arranged at the bottom of the saccharification reaction tank 111, so as to reduce the difficulty of the sample liquid entering the first pipeline 116 and the pipeline between the first end and the second end of the six-way valve, and reduce the residual amount of the sample liquid in the saccharification reaction tank 111, and reduce the reagent cost.
[0110] Optionally, as shown in Figure 6 Figure 7 is a structural schematic diagram of another embodiment of the saccharification detection device of the application. The saccharification detection device 11 can further include a high-pressure establishing assembly 117, one end of the high-pressure establishing assembly 117 is connected with the saccharification power assembly 113, and the other end is connected with the second valve 114. In turn, the saccharification power assembly 113 is further used to provide the eluent provided by the saccharification reagent assembly 112 to the high-pressure establishing assembly 117, so that the saccharification detection assembly 115 maintains a high-pressure state under the power of the high-pressure establishing assembly 117.
[0111] The eluent can be a diluent or other auxiliary reagents for saccharification detection, etc. The eluent can fill the internal pipeline of the saccharification detection device 11. Under the high-pressure environment established by the high-pressure establishing assembly 117, the eluent in the pipeline will be consumed. Therefore, the saccharification power assembly 113 can transport the eluent in the saccharification reagent assembly 112 to the high-pressure establishing assembly 117 to supplement the eluent consumed by the high-pressure establishing assembly 117. In addition, the high-pressure establishing assembly 117 can also provide power to the saccharification detection assembly 115 to maintain the high-pressure state of the saccharification detection assembly 115, thereby improving the detection efficiency of the saccharification detection assembly 115 on the sample liquid.
[0112] In summary, the sample analyzer 1 provided by the application includes a saccharification detection device 11, a blood routine detection device 12, a blood sedimentation detection device 15, a sampling device 13 and a sampling power device 14. The sampling device 13 is used to provide the sample to be tested to the blood routine detection device 12, the saccharification detection device 11 and the blood sedimentation detection device 15, thereby improving the practicability of the sampling device 13 and improving the operation efficiency of the sample analyzer 1.
[0113] In addition, the sampling power device 14 includes a first valve 141, a first power assembly 142 and a second power assembly 143. The capacity of the second power assembly 143 is greater than or equal to the capacity of the first power assembly 142. Through the cooperation of the first power assembly 142 and the second power assembly 143, the sampling device 13 can realize the suction efficiency of the sample to be tested, and at the same time, the accuracy of the sampling device 13 in distributing the sample to be tested to the blood routine detection device 12 and the saccharification detection device 11 can be improved, thereby improving the practicability of the sample analyzer 1.
[0114] In one embodiment, the control device (not shown) within the sample analyzer 1 can independently control the glycation detection device 11, the routine blood test device 12, and the erythrocyte sedimentation rate (ESR) test device 15. That is, when the sample to be tested does not require glycation detection, the control device can control the glycation detection device 11 to stop operating, while the routine blood test device 12 and the ESR test device 15 continue to operate. By controlling multiple detection devices individually, the practicality of the sample analyzer 1 is improved.
[0115] Furthermore, when the saccharification detection device 11 is stopped from operation, the chromatography column in the saccharification detection component 115 can be moved to an environment of 2-8°C for cold storage to avoid instrument failure due to prolonged non-use of saccharification detection and improve the safety of the sample analyzer 1.
[0116] This application also provides another sample analyzer, such as Figure 7 The above, This is a schematic diagram of the fourth embodiment of the sample analyzer of this application. The sample analyzer 1 provided in this embodiment includes a glycation detection device 11, a routine blood test device 12, a specific protein detection device 19, an erythrocyte sedimentation rate (ESR) detection device 15, a sampling device 13, and a sampling power device 14. Among them, the specific protein detection device 19 can perform specific protein detection on the sample to be tested, and is used to detect specific functional proteins in serum.
[0117] Glycation detection device 11, blood routine detection device 12, specific protein detection device 19, and erythrocyte sedimentation rate (ESR) detection device 15 are arranged at intervals. Sampling device 13 and sampling power device 14 are connected and arranged at intervals with glycosylation detection device 11, blood routine detection device 12, specific protein detection device 19, and ESR detection device 15. Sampling power device 14 is used to provide power for sampling device 13 to aspirate and expel the sample to be tested. Sampling device 13 is used to provide the sample to be tested to glycosylation detection device 11, blood routine detection device 12, specific protein detection device 19, and ESR detection device 15.
[0118] The sample analyzer 1 provided in this application includes a glycation detection device 11, a complete blood count (CBC) detection device 12, a specific protein detection device 19, and an erythrocyte sedimentation rate (ESR) detection device 15. It enables the sample analyzer 1 to perform glycation detection, CBC detection, specific protein detection, and ESR detection on the sample to be tested, thus improving the practicality of the sample analyzer 1. Simultaneously, the sampling device 13 can provide the sample to be tested for the glycation detection device 11, CBC detection device 12, specific protein detection device 19, and ESR detection device 15, improving the practicality of the sampling device 13, reducing the component cost in the sample analyzer 1, further enhancing the practicality of the sample analyzer 1, and improving the user experience of the sample analyzer 1.
[0119] Further, the sampling power device 14 provided by the embodiment includes a first valve, a first power component and a second power component.
[0120] The first power component is connected with the sampling device, and the second power component is connected or disconnected with the first power component through the first valve, and the capacity of the second power component is greater than or equal to the capacity of the first power component. The first power component and the second power component can be syringes with different capacities.
[0121] Specifically, when the first power component and the second power component are connected, the second power component is used to provide power for the sampling device to suck the sample to be tested; when the first power component and the second power component are disconnected, the first power component is used to provide power for the sampling device to distribute the sample to be tested.
[0122] The sampling device 13 can provide the sample to be tested for the blood routine detection device 12, the glycation detection device 11, the blood sedimentation detection device 15 and the specific protein detection device 19, that is, the sampling device 13 can suck the sample to be tested required by the blood routine detection device 12, the glycation detection device 11, the blood sedimentation detection device 15 and the specific protein detection device 19 at one time, and then move to the blood routine detection device 12, the glycation detection device 11, the blood sedimentation detection device 15 and the specific protein detection device 19 to distribute the corresponding sample to be tested. Therefore, during the process of sucking the sample to be tested by the sampling device 13, the second power component with a larger capacity can be used to provide power, so as to improve the sucking efficiency of the sampling device 13 on the sample to be tested. When the sampling device 13 distributes the sample to be tested to the blood routine detection device 12, the glycation detection device 11 and the specific protein detection device 19, since the amount of the sample to be tested injected into the glycation detection device 11, the blood routine detection device 12 and the specific protein detection device 19 is required to be accurate, the first power component with a smaller capacity is used to provide power for the sampling device 13 to distribute the sample to be tested, so as to improve the accuracy of sampling of the sampling device 13.
[0123] Further, when the sample to be tested needs to be detected by blood sedimentation, the first valve is switched to make the first power component and the second power component communicate, and the second power component provides power to make the sample to be tested reach the corresponding pipeline section of the blood sedimentation detection device 15. The second power component with a larger capacity can accelerate the efficiency of sucking the sample to be tested to the corresponding pipeline section of the blood sedimentation detection device 15, realize effective disaggregation of the sample to be tested by blood sedimentation, and improve the accuracy of blood sedimentation detection.
[0124] The application also provides another sample analyzer 1, which includes a glycation detection device 11, a blood routine detection device 12 and a sampling device 13.
[0125] The sampling device 13, the glycated detection device 11 and the blood routine detection device 12 are arranged at intervals, and the sampling device 13 is used to provide the sample to be detected to the reaction pool of the blood routine detection device 12 and the glycated detection device 11.
[0126] The glycated detection device 11 can include a glycated reaction pool 111, a glycated reagent assembly 112, a glycated power assembly 113, a second valve 114 and a glycated detection assembly 115 connected in sequence. The glycated reaction pool 111 is connected with the second valve 114 through a first pipeline 116. The glycated power assembly 113 is used to deliver the glycated hemolytic agent provided by the glycated reagent assembly 112 to the glycated reaction pool 111 through the first pipeline 116, and deliver the sample to be detected and the glycated hemolytic agent to the glycated detection assembly 115 through the first pipeline 116 and the second valve 114 for glycated detection.
[0127] Through the arrangement of the internal devices of the glycated detection device 11, the glycated hemolytic agent and the sample to be detected can flow in the first pipeline 116. The glycated hemolytic agent does not need to be injected into the glycated reaction pool 111 by an additional sampling assembly, and the sample to be detected in the glycated reaction pool 111 does not need to be moved to the glycated detection assembly 115 by an additional sampling assembly. The device arrangement of the glycated detection device 11 is simplified, the pipeline structure is simplified, the transportation efficiency of the reagent in the glycated detection device 11 is improved, and the operation efficiency of the sample analyzer 1 is improved while the cost is reduced.
[0128] The above is only the embodiment of the present application, and does not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation using the content of the specification and the drawings, or direct or indirect application in other related technical fields, is also included in the patent protection scope of the present application.
Claims
1. A sample analyzer characterized by, The sample analyzer comprises a glycosylation detection device, a blood routine detection device, a sampling device and a sampling power device; The glycosylation detection device is arranged apart from the blood routine detection device, the sampling device is connected with the sampling power device and arranged apart from the glycosylation detection device and the blood routine detection device; The sampling device is used for providing the blood routine detection device and the glycosylation detection device with a sample to be detected; The sampling power device comprises a first valve, a first power assembly and a second power assembly; the first power assembly is connected with the sampling device; the second power assembly is connected or disconnected with the first power assembly through the first valve; When the first power assembly is connected with the second power assembly, the second power assembly is used for providing power for the sampling device to suck the sample to be detected; When the first power assembly is disconnected with the second power assembly, the first power assembly is used for providing power for the sampling device to distribute the sample to be detected; The capacity of the second power assembly is greater than or equal to the capacity of the first power assembly.
2. The sample analyzer of claim 1, wherein, The sample analyzer further comprises a blood sedimentation detection device arranged on a connecting pipeline between the sampling device and the first power assembly; When the sample to be detected needs to be detected by the blood sedimentation detection device, the first valve is switched to make the first power assembly and the second power assembly communicate, and the second power assembly provides power to make the sample to be detected reach a pipeline segment corresponding to the blood sedimentation detection device.
3. The sample analyzer of claim 1 or 2, wherein, The capacity of the second power assembly is greater than or equal to 10 times the capacity of the first power assembly; The capacity of the first power assembly is less than or equal to 250 μL, and the capacity of the second power assembly is less than or equal to 10 mL.
4. The sample analyzer of claim 1, wherein, The glycosylation detection device comprises a glycosylation reaction pool, a glycosylation reagent assembly, a glycosylation power assembly, a second valve and a glycosylation detection assembly connected in sequence; The glycosylation reaction pool is connected with the second valve through a first pipeline and used for receiving the sample to be detected injected by the sampling device; The glycosylation power assembly is used for conveying a glycosylation hemolytic agent provided by the glycosylation reagent assembly to the glycosylation reaction pool through the second valve and the first pipeline, and conveying a sample to be detected obtained by reacting the sample to be detected and the glycosylation hemolytic agent to the glycosylation detection assembly through the first pipeline and the second valve.
5. The sample analyzer of claim 4, wherein, The sample analyzer further comprises a third valve and a fourth valve; A first end of the third valve is connected with the sampling device, and a second end of the third valve is connected with the sampling power device; A first end of the fourth valve is connected with the glycosylation reaction pool, a second end of the fourth valve is connected with the second valve through the first pipeline, and a third end of the fourth valve is connected with a third end of the third valve.
6. The sample analyzer of claim 5, wherein, When the sample to be detected sucked by the sampling device is a sample to be detected after a hemolysis reaction is completed, the glycosylation power assembly is used for conveying the sample to be detected to the glycosylation detection assembly through the third valve, the fourth valve and the second valve.
7. The sample analyzer of claim 5, wherein, The saccharification power assembly is also used for conveying the saccharification lysing agent provided by the saccharification reagent assembly to the sampling device via the second valve, the fourth valve and the third valve.
8. The sample analyzer of claim 4, wherein, The sample analyzer further comprises a fifth valve, a first end of the fifth valve being connected with the saccharification reaction tank, and a second end of the fifth valve being connected with the first end of the second valve through the first pipeline.
9. A sample analyzer characterized by, The sample analyzer comprises a saccharification detection device, a routine blood detection device, a specific protein detection device, a blood sedimentation detection device, a sampling device and a sampling power device. The saccharification detection device, the routine blood detection device, the specific protein detection device and the blood sedimentation detection device are arranged at intervals, the sampling device is connected with the sampling power device and arranged at intervals with the saccharification detection device, the routine blood detection device, the specific protein detection device and the blood sedimentation detection device. The sampling power device is used for providing power for the sampling device to suck and discharge the sample to be detected, and the sampling device is used for providing the sample to be detected to the saccharification detection device, the routine blood detection device, the specific protein detection device and the blood sedimentation detection device.
10. A sample analyzer characterized by, The sample analyzer comprises a saccharification detection device, a routine blood detection device and a sampling device. The sampling device is used for providing the sample to be detected to the reaction tank of the routine blood detection device and the saccharification detection device. The saccharification detection device comprises a saccharification reaction tank, a saccharification reagent assembly, a saccharification power assembly, a second valve and a saccharification detection assembly which are connected in sequence. The saccharification power assembly is used for conveying the saccharification lysing agent provided by the saccharification reagent assembly to the saccharification reaction tank through the first pipeline, and conveying the sample to be detected and the saccharification lysing agent after reaction to the saccharification detection assembly through the first pipeline and the second valve.